| UniProt ID | CC112_HUMAN | |
|---|---|---|
| UniProt AC | Q8NEF3 | |
| Protein Name | Coiled-coil domain-containing protein 112 | |
| Gene Name | CCDC112 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 446 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIGPTGSGPLLHIPHRAIPTWRQGIQRRV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Ubiquitination | ---MEKDKHSHFYNQ ---CCCCCCCCCCCC | 59.06 | 29967540 | |
| 13 | Ubiquitination | HSHFYNQKSDFRIEH CCCCCCCCCCHHCCH | 48.64 | 29967540 | |
| 29 | Ubiquitination | MLEELENKLIHSRKT HHHHHHHHHHHCCHH | 39.17 | 29967540 | |
| 47 | Ubiquitination | KIQQQLAKIHNNVKK HHHHHHHHHHHHHHH | 53.76 | 29967540 | |
| 63 | Ubiquitination | QHQLKDVKPTPDFVE HHHHCCCCCCHHHHH | 53.99 | 29967540 | |
| 71 | Ubiquitination | PTPDFVEKLREMMEE CCHHHHHHHHHHHHH | 47.76 | 29967540 | |
| 78 (in isoform 2) | Ubiquitination | - | 37.39 | - | |
| 88 | Ubiquitination | NAINTFKEEQRLIYE HHHHHCHHHHHHHHH | 55.99 | 29967540 | |
| 94 | Phosphorylation | KEEQRLIYEELIKEE HHHHHHHHHHHHHHH | 14.14 | 25884760 | |
| 96 (in isoform 2) | Ubiquitination | - | 38.53 | - | |
| 96 | Ubiquitination | EQRLIYEELIKEEKT HHHHHHHHHHHHHCC | 38.53 | 29967540 | |
| 102 | Acetylation | EELIKEEKTTNNELS HHHHHHHCCCHHHHH | 62.84 | 19827645 | |
| 104 | Phosphorylation | LIKEEKTTNNELSAI HHHHHCCCHHHHHHH | 47.30 | 19835603 | |
| 112 | Ubiquitination | NNELSAISRKIDTWA HHHHHHHHHHHCCHH | 27.51 | 29967540 | |
| 112 (in isoform 2) | Ubiquitination | - | 27.51 | - | |
| 112 | Phosphorylation | NNELSAISRKIDTWA HHHHHHHHHHHCCHH | 27.51 | 19835603 | |
| 114 | Ubiquitination | ELSAISRKIDTWALG HHHHHHHHHCCHHCC | 37.84 | 29967540 | |
| 127 | Ubiquitination | LGNSETEKAFRAISS CCCHHHHHHHHHHHC | 61.31 | 29967540 | |
| 130 | Ubiquitination | SETEKAFRAISSKVP HHHHHHHHHHHCCCC | 35.55 | 29967540 | |
| 140 | Ubiquitination | SSKVPVDKVTPSTLP HCCCCCCCCCCCCCC | 48.52 | - | |
| 142 | Phosphorylation | KVPVDKVTPSTLPEE CCCCCCCCCCCCCHH | 19.77 | 27050516 | |
| 144 | O-linked_Glycosylation | PVDKVTPSTLPEEVL CCCCCCCCCCCHHHH | 32.96 | OGP | |
| 146 | Ubiquitination | DKVTPSTLPEEVLDF CCCCCCCCCHHHHCH | 6.20 | 29967540 | |
| 154 | Ubiquitination | PEEVLDFEKFLQQTG CHHHHCHHHHHHHHC | 42.43 | 29967540 | |
| 155 | Ubiquitination | EEVLDFEKFLQQTGG HHHHCHHHHHHHHCC | 51.90 | 29967540 | |
| 177 | Ubiquitination | YDHQNFVKVRNKHKG CCCCCCHHHCCCCCC | 31.19 | 29967540 | |
| 177 | Phosphorylation | YDHQNFVKVRNKHKG CCCCCCHHHCCCCCC | 31.19 | 27642862 | |
| 197 (in isoform 2) | Ubiquitination | - | 44.11 | - | |
| 197 | Ubiquitination | EEVLEHLPGKTQDEV HHHHHHCCCCCHHHH | 44.11 | 29967540 | |
| 199 | Ubiquitination | VLEHLPGKTQDEVQQ HHHHCCCCCHHHHHH | 40.86 | 29967540 | |
| 209 | Ubiquitination | DEVQQHEKWYQKFLA HHHHHHHHHHHHHHH | 49.42 | 29967540 | |
| 210 | Ubiquitination | EVQQHEKWYQKFLAL HHHHHHHHHHHHHHH | 9.60 | 29967540 | |
| 223 (in isoform 2) | Ubiquitination | - | 56.99 | - | |
| 238 | Ubiquitination | KKQQKREEIFKLKEK HHHHHHHHHHHHHHH | 58.73 | 29967540 | |
| 260 | Ubiquitination | FHNKQEDNQKQKEEQ CCCHHHHHHHHHHHH | 50.63 | 29967540 | |
| 260 (in isoform 2) | Ubiquitination | - | 50.63 | - | |
| 282 | Ubiquitination | VEAWKKQKSIEMSMK HHHHHHHHHHHHHHH | 63.38 | 29967540 | |
| 283 | Phosphorylation | EAWKKQKSIEMSMKC HHHHHHHHHHHHHHH | 22.68 | 27251275 | |
| 287 | Phosphorylation | KQKSIEMSMKCASQL HHHHHHHHHHHHHHH | 11.42 | 24719451 | |
| 292 | Ubiquitination | EMSMKCASQLKEEEE HHHHHHHHHHHHHHH | 45.58 | 29967540 | |
| 292 | Phosphorylation | EMSMKCASQLKEEEE HHHHHHHHHHHHHHH | 45.58 | 29449344 | |
| 336 | Ubiquitination | EEFLRLEKEIREKAE HHHHHHHHHHHHHHH | 64.13 | 29967540 | |
| 347 | Acetylation | EKAEKAEKRKNAADE HHHHHHHHHHHHHHH | 73.80 | 18585251 | |
| 366 | Phosphorylation | QERDLHKLELKILDR HHHHHHHHHHHHHHH | 6.93 | 27251275 | |
| 408 (in isoform 2) | Ubiquitination | - | 26.28 | - | |
| 409 | O-linked_Glycosylation | PSRLYKPTKGWEERT HHHCCCCCCCHHHHH | 37.73 | 55834759 | |
| 419 | Ubiquitination | WEERTKKIGPTGSGP HHHHHCCCCCCCCCC | 9.47 | 29967540 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CC112_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CC112_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CC112_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| TEX9_HUMAN | TEX9 | physical | 16189514 | |
| LURA1_HUMAN | LURAP1 | physical | 16189514 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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