ZN572_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN572_HUMAN
• UniProt AC: Q7Z3I7
• Protein Name: Zinc finger protein 572
• Gene Name: ZNF572
• Organism: Homo sapiens (Human).
• Sequence Length: 529
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MEQEKKLLVSDSNSFMERESLKSPFTGDTSMNNLETVHHNNSKADKLKEKPSEWSKRHRPQHYKHEDAKEMPLTWVQDEIWCHDSYESDGKSENWGNFIAKEEEKPNHQEWDSGEHTNACVQQNSSFVDRPYKCSECWKSFSNSSHLRTHQRTHSGEKPYKCSECAKCFCNSSHLIQHLRMHTGEKPYQCGECGKSFSNTSHLIIHERTHTGEKPYKCPECGKRFSSSSHLIQHHRSHTGEKPYECSVCGKGFSHSYVLIEHQRTHTGEKPYKCPDCGKSFSQSSSLIRHQRTHTGEKPYKCLECEKSFGCNSTLIKHQRIHTGEKPYQCPECGKNFSRSSNLITHQKMHTGEKSYESSEYEESLGQNCNVIEECRIQLGEKPYRCCECGKSFGLSSHLIRHQRTHTGEKPYRCSECWKTFSQSSTLVIHQRTHTGEKPYKCPDCGESFSQSFNLIRHRRTHIGEKPYKCTSCEKCFSRSAYLSQHRKIHVEKPFESPDVGDFPHEWTWKNCSGEMPFISSFSVSNSSS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Sumoylation	---MEQEKKLLVSDS ---CHHHHCEEECCC	48.71	28112733
6	Sumoylation	--MEQEKKLLVSDSN --CHHHHCEEECCCC	46.42	28112733
10	Phosphorylation	QEKKLLVSDSNSFME HHHCEEECCCCCHHC	34.98	22964224
144	Phosphorylation	CWKSFSNSSHLRTHQ HHHHHCCCHHHEEEC	20.24	-
145	Phosphorylation	WKSFSNSSHLRTHQR HHHHCCCHHHEEECC	30.69	-
158	Ubiquitination	QRTHSGEKPYKCSEC CCCCCCCCCCCHHHH	58.11	-
172	Phosphorylation	CAKCFCNSSHLIQHL HHHHHHCHHHHHHHH	21.95	-
173	Phosphorylation	AKCFCNSSHLIQHLR HHHHHCHHHHHHHHH	14.34	-
209	Phosphorylation	HLIIHERTHTGEKPY EEEEEECCCCCCCCC	22.32	28348404
211	Phosphorylation	IIHERTHTGEKPYKC EEEECCCCCCCCCCC	46.56	26270265
214	Ubiquitination	ERTHTGEKPYKCPEC ECCCCCCCCCCCCCC	55.80	-
216	Phosphorylation	THTGEKPYKCPECGK CCCCCCCCCCCCCCC	35.97	29438985
265	Phosphorylation	VLIEHQRTHTGEKPY EEEEECCCCCCCCCC	19.74	28348404
267	Phosphorylation	IEHQRTHTGEKPYKC EEECCCCCCCCCCCC	46.56	26270265
270	Ubiquitination	QRTHTGEKPYKCPDC CCCCCCCCCCCCCCC	55.80	-
285	Phosphorylation	GKSFSQSSSLIRHQR CCCCCCCHHHHHCCC	22.87	24719451
286	Phosphorylation	KSFSQSSSLIRHQRT CCCCCCHHHHHCCCC	32.82	24719451
293	Phosphorylation	SLIRHQRTHTGEKPY HHHHCCCCCCCCCCE	19.74	28348404
295	Phosphorylation	IRHQRTHTGEKPYKC HHCCCCCCCCCCEEE	46.56	24719451
298	Ubiquitination	QRTHTGEKPYKCLEC CCCCCCCCCEEEEEE	55.80	-
313	Phosphorylation	EKSFGCNSTLIKHQR HHHHCCCCEEEECCC	28.77	-
317	Ubiquitination	GCNSTLIKHQRIHTG CCCCEEEECCCCCCC	36.48	-
323	Phosphorylation	IKHQRIHTGEKPYQC EECCCCCCCCCCCCC	44.67	28111955
405	Phosphorylation	HLIRHQRTHTGEKPY HHHHCCCCCCCCCCE	19.74	-
407	Phosphorylation	IRHQRTHTGEKPYRC HHCCCCCCCCCCEEC	46.56	24719451
410	Acetylation	QRTHTGEKPYRCSEC CCCCCCCCCEECHHH	49.01	30593787
433	Phosphorylation	TLVIHQRTHTGEKPY EEEEEEECCCCCCCC	19.74	28348404
435	Phosphorylation	VIHQRTHTGEKPYKC EEEEECCCCCCCCCC	46.56	26270265
438	Ubiquitination	QRTHTGEKPYKCPDC EECCCCCCCCCCCCC	55.80	-
438	Acetylation	QRTHTGEKPYKCPDC EECCCCCCCCCCCCC	55.80	7428817
461	O-linked_Glycosylation	NLIRHRRTHIGEKPY HHHHCCCCCCCCCCC	20.15	30379171
461	Phosphorylation	NLIRHRRTHIGEKPY HHHHCCCCCCCCCCC	20.15	-
466	Sumoylation	RRTHIGEKPYKCTSC CCCCCCCCCCCCCCH	48.73	-
466	Sumoylation	RRTHIGEKPYKCTSC CCCCCCCCCCCCCCH	48.73	-
513	Phosphorylation	EWTWKNCSGEMPFIS CEECCCCCCCCCEEE	47.37	21118733
520	Phosphorylation	SGEMPFISSFSVSNS CCCCCEEEEEEECCC	26.22	21118733
523	Phosphorylation	MPFISSFSVSNSSS- CCEEEEEEECCCCC-	26.95	21118733
525	Phosphorylation	FISSFSVSNSSS--- EEEEEEECCCCC---	29.78	21118733
527	Phosphorylation	SSFSVSNSSS----- EEEEECCCCC-----	25.18	21118733
528	Phosphorylation	SFSVSNSSS------ EEEECCCCC------	44.30	21118733
529	Phosphorylation	FSVSNSSS------- EEECCCCC-------	44.02	21118733

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN572_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN572_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN572_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KLC3_HUMAN	KLC3	physical	25416956
DEUP1_HUMAN	CCDC67	physical	25416956
KR107_HUMAN	KRTAP10-7	physical	25416956
KR109_HUMAN	KRTAP10-9	physical	25416956
KR101_HUMAN	KRTAP10-1	physical	25416956
KR108_HUMAN	KRTAP10-8	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.