CALL3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CALL3_HUMAN
• UniProt AC: P27482
• Protein Name: Calmodulin-like protein 3
• Gene Name: CALML3
• Organism: Homo sapiens (Human).
• Sequence Length: 149
• Protein Description: May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 heavy chain protein. May compete with calmodulin by binding, with different affinities, to cellular substrates..
• Protein Sequence: MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVLVSK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MADQLTEEQVTEF --CCCCCCHHHHHHH	31.66	20068231
11	Phosphorylation	QLTEEQVTEFKEAFS CCCHHHHHHHHHHHH	35.08	20068231
18	Phosphorylation	TEFKEAFSLFDKDGD HHHHHHHHHCCCCCC	34.86	21815630
35	Phosphorylation	ITTRELGTVMRSLGQ EEHHHHHHHHHHCCC	24.61	26437602
38	Methylation	RELGTVMRSLGQNPT HHHHHHHHHCCCCCC	25.13	-
116	Methylation	VMTRLGEKLSDEEVD HHHHHHHCCCHHHHH	52.04	-
118	Phosphorylation	TRLGEKLSDEEVDEM HHHHHCCCHHHHHHH	54.78	25106551
125	Oxidation	SDEEVDEMIRAADTD CHHHHHHHHHHHCCC	1.86	16446289
139	Phosphorylation	DGDGQVNYEEFVRVL CCCCCCCHHHHHHHH	20.27	25106551
148	Phosphorylation	EFVRVLVSK------ HHHHHHHCC------	28.61	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CALL3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CALL3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CALL3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
K1683_HUMAN	KIAA1683	physical	16189514
MK04_HUMAN	MAPK4	physical	21988832
K1683_HUMAN	KIAA1683	physical	25416956
CK065_HUMAN	C11orf65	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.