| UniProt ID | CSRN2_HUMAN | |
|---|---|---|
| UniProt AC | Q9H175 | |
| Protein Name | Cysteine/serine-rich nuclear protein 2 | |
| Gene Name | CSRNP2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 543 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity (By similarity). May play a role in apoptosis.. | |
| Protein Sequence | MDAFTGSGLKRKFDDVDVGSSVSNSDDEISSSDSADSCDSLNPPTTASFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPAAPDEEPSPTASCSLTGAQGSETQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSSIESLGVCILEEPLAVPEELCPGLTAPILIQAQLPPGSSVLCFTENSDHPTASTVNSPSYLNSGPLVYYQVEQRPVLGVKGEPGTEEGSASFPKEKDLNVFSLPVTSLVACSSTDPAALCKSEVGKTPTLEALLPEDCNPEEPENEDFHPSWSPSSLPFRTDNEEGCGMVKTSQQNEDRPPEDSSLELPLAV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MDAFTGSG -------CCCCCCCC | 8.28 | 22814378 | |
| 45 | Phosphorylation | CDSLNPPTTASFTPT CCCCCCCCCCCCCHH | 35.93 | 30576142 | |
| 48 | Phosphorylation | LNPPTTASFTPTSIL CCCCCCCCCCHHHHH | 27.79 | 30576142 | |
| 53 | Phosphorylation | TASFTPTSILKRQKQ CCCCCHHHHHHHHHH | 27.42 | 24719451 | |
| 72 | O-linked_Glycosylation | NVRFDQVTVYYFARR CCCHHHHHHHEEEEC | 9.35 | 29351928 | |
| 91 | Phosphorylation | SVPSQGGSSLGMAQR CCCCCCCCHHHHHHH | 29.25 | - | |
| 200 | Ubiquitination | HRIDAEEKQELRAIR CCCCHHHHHHHHHHH | 40.35 | - | |
| 234 | Ubiquitination | ACSQAGIKCQVDRMS HHCCCCCEECEECCC | 20.07 | - | |
| 267 | Phosphorylation | FNPIRVRTHYLHTIM CCCEEEEHHHHHHHH | 16.41 | 29449344 | |
| 269 | Phosphorylation | PIRVRTHYLHTIMKL CEEEEHHHHHHHHHH | 10.28 | 28122231 | |
| 272 | Phosphorylation | VRTHYLHTIMKLELE EEHHHHHHHHHHHHH | 21.85 | 29449344 | |
| 280 | Phosphorylation | IMKLELESKRQVSRP HHHHHHHHCCCCCCC | 45.84 | 28122231 | |
| 281 | Ubiquitination | MKLELESKRQVSRPA HHHHHHHCCCCCCCC | 37.16 | - | |
| 472 | Acetylation | TDPAALCKSEVGKTP CCHHHHCCCCCCCCC | 50.96 | 18525597 | |
| 477 | Acetylation | LCKSEVGKTPTLEAL HCCCCCCCCCCHHHH | 57.41 | 18525605 | |
| 502 | Phosphorylation | ENEDFHPSWSPSSLP CCCCCCCCCCCCCCC | 31.45 | 26074081 | |
| 504 | Phosphorylation | EDFHPSWSPSSLPFR CCCCCCCCCCCCCCC | 21.17 | 26074081 | |
| 506 | Phosphorylation | FHPSWSPSSLPFRTD CCCCCCCCCCCCCCC | 38.70 | 26074081 | |
| 507 | Phosphorylation | HPSWSPSSLPFRTDN CCCCCCCCCCCCCCC | 43.37 | 26074081 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CSRN2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CSRN2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CSRN2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of CSRN2_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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