GLB1L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GLB1L_HUMAN
• UniProt AC: Q6UWU2
• Protein Name: Beta-galactosidase-1-like protein
• Gene Name: GLB1L
• Organism: Homo sapiens (Human).
• Sequence Length: 654
• Subcellular Localization: Secreted .
• Protein Description: Probable glycosyl hydrolase..
• Protein Sequence: MAPKKLSCLRSLLLPLSLTLLLPQADTRSFVVDRGHDRFLLDGAPFRYVSGSLHYFRVPRVLWADRLLKMRWSGLNAIQFYVPWNYHEPQPGVYNFNGSRDLIAFLNEAALANLLVILRPGPYICAEWEMGGLPSWLLRKPEIHLRTSDPDFLAAVDSWFKVLLPKIYPWLYHNGGNIISIQVENEYGSYRACDFSYMRHLAGLFRALLGEKILLFTTDGPEGLKCGSLRGLYTTVDFGPADNMTKIFTLLRKYEPHGPLVNSEYYTGWLDYWGQNHSTRSVSAVTKGLENMLKLGASVNMYMFHGGTNFGYWNGADKKGRFLPITTSYDYDAPISEAGDPTPKLFALRDVISKFQEVPLGPLPPPSPKMMLGPVTLHLVGHLLAFLDLLCPRGPIHSILPMTFEAVKQDHGFMLYRTYMTHTIFEPTPFWVPNNGVHDRAYVMVDGVFQGVVERNMRDKLFLTGKLGSKLDILVENMGRLSFGSNSSDFKGLLKPPILGQTILTQWMMFPLKIDNLVKWWFPLQLPKWPYPQAPSGPTFYSKTFPILGSVGDTFLYLPGWTKGQVWINGFNLGRYWTKQGPQQTLYVPRFLLFPRGALNKITLLELEDVPLQPQVQFLDKPILNSTSTLHRTHINSLSADTLSASEPMELSGH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MAPKKLSCLRSLLL -CCCHHHHHHHHHHH	21.71	24719451
27	Phosphorylation	LLLPQADTRSFVVDR EECCCCCCCEEEEEC	31.09	22210691
97	N-linked_Glycosylation	QPGVYNFNGSRDLIA CCCEECCCCCHHHHH	43.84	UniProtKB CARBOHYD
147	Phosphorylation	KPEIHLRTSDPDFLA CCEEEECCCCHHHHH	43.79	26074081
148	Phosphorylation	PEIHLRTSDPDFLAA CEEEECCCCHHHHHH	40.49	26074081
225	Acetylation	TDGPEGLKCGSLRGL CCCCCCCCCCCCCCC	47.62	25038526
234	Phosphorylation	GSLRGLYTTVDFGPA CCCCCCEEEEECCCC	25.94	-
235	Phosphorylation	SLRGLYTTVDFGPAD CCCCCEEEEECCCCH	12.43	-
243	N-linked_Glycosylation	VDFGPADNMTKIFTL EECCCCHHHHHHHHH	41.97	UniProtKB CARBOHYD
249	Phosphorylation	DNMTKIFTLLRKYEP HHHHHHHHHHHHCCC	28.49	24260401
398	Phosphorylation	CPRGPIHSILPMTFE CCCCCHHHHCCCCHH	26.92	22210691
403	Phosphorylation	IHSILPMTFEAVKQD HHHHCCCCHHHHHCC	19.18	22210691
417	Dimethylation	DHGFMLYRTYMTHTI CCCEEEEEEEEECCC	18.54	-
469	Phosphorylation	FLTGKLGSKLDILVE EEECCCHHHHHHHHC	40.25	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GLB1L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GLB1L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GLB1L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.