dbPTM

CSN5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CSN5_HUMAN
UniProt AC	Q92905
Protein Name	COP9 signalosome complex subunit 5
Gene Name	COPS5
Organism	Homo sapiens (Human).
Sequence Length	334
Subcellular Localization	Cytoplasm, cytosol . Nucleus . Cytoplasm, perinuclear region . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle . Nuclear localization is diminished in the presence of IFIT3.
Protein Description	Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. It however has no metalloprotease activity by itself and requires the other subunits of the CSN complex. Interacts directly with a large number of proteins that are regulated by the CSN complex, confirming a key role in the complex. Promotes the proteasomal degradation of BRSK2..
Protein Sequence	MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKLAKATRDSCKTTIEAIHGLMSQVIKDKLFNQINIS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAASGSGMA ------CCCCCCCHH	15.44	18850735
4	Phosphorylation	----MAASGSGMAQK ----CCCCCCCHHHH	24.77	-
11	Ubiquitination	SGSGMAQKTWELANN CCCCHHHHHHHHHHH	46.17	21906983
24	Phosphorylation	NNMQEAQSIDEIYKY HHHHHHHHHHHHHCC	38.77	24719451
30	Ubiquitination	QSIDEIYKYDKKQQQ HHHHHHHCCCHHHHH	53.27	21906983
33	Ubiquitination	DEIYKYDKKQQQEIL HHHHCCCHHHHHHHH	49.76	21906983
34	Ubiquitination	EIYKYDKKQQQEILA HHHCCCHHHHHHHHH	50.90	21906983
43	Ubiquitination	QQEILAAKPWTKDHH HHHHHHCCCCCCCCH	35.17	21906983
47	Acetylation	LAAKPWTKDHHYFKY HHCCCCCCCCHHHHH	51.72	19608861
47	Ubiquitination	LAAKPWTKDHHYFKY HHCCCCCCCCHHHHH	51.72	21906983
53	Ubiquitination	TKDHHYFKYCKISAL CCCCHHHHHHHHHHH	42.44	-
53	Acetylation	TKDHHYFKYCKISAL CCCCHHHHHHHHHHH	42.44	26051181
54	Phosphorylation	KDHHYFKYCKISALA CCCHHHHHHHHHHHH	6.78	-
56	Ubiquitination	HHYFKYCKISALALL CHHHHHHHHHHHHHH	36.28	21906983
58	Phosphorylation	YFKYCKISALALLKM HHHHHHHHHHHHHHH	11.61	-
71	Phosphorylation	KMVMHARSGGNLEVM HHHHHHHCCCCCEEE	52.41	21712546
114	Phosphorylation	VNAQAAAYEYMAAYI HHHHHHHHHHHHHHH	11.67	27642862
120	Phosphorylation	AYEYMAAYIENAKQV HHHHHHHHHHHHHHH	10.14	18669648
125	Ubiquitination	AAYIENAKQVGRLEN HHHHHHHHHHCCHHH	58.03	21906983
180	Ubiquitination	TRTISAGKVNLGAFR CCEEECCCCCCCEEC	27.89	-
191	Ubiquitination	GAFRTYPKGYKPPDE CEECCCCCCCCCCCC	65.54	21890473
194	Ubiquitination	RTYPKGYKPPDEGPS CCCCCCCCCCCCCCC	59.76	21906983
194	Acetylation	RTYPKGYKPPDEGPS CCCCCCCCCCCCCCC	59.76	25953088
201	Phosphorylation	KPPDEGPSEYQTIPL CCCCCCCCCCCCEEH	60.85	28796482
203	Phosphorylation	PDEGPSEYQTIPLNK CCCCCCCCCCEEHHH	18.46	28796482
205	Phosphorylation	EGPSEYQTIPLNKIE CCCCCCCCEEHHHCC	24.54	28796482
210	Ubiquitination	YQTIPLNKIEDFGVH CCCEEHHHCCCCCCC	55.97	-
210	Acetylation	YQTIPLNKIEDFGVH CCCEEHHHCCCCCCC	55.97	26051181
236	Ubiquitination	FKSSLDRKLLELLWN HCHHHHHHHHHHHHH	58.03	21906983
261	Phosphorylation	SLLTNADYTTGQVFD CCCCCCCCCCCCCEE	12.09	20068231
262	Phosphorylation	LLTNADYTTGQVFDL CCCCCCCCCCCCEEH	25.62	20068231
263	Phosphorylation	LTNADYTTGQVFDLS CCCCCCCCCCCEEHH	21.27	20068231
270	Phosphorylation	TGQVFDLSEKLEQSE CCCCEEHHHHHHHHH	34.23	20068231
276	Phosphorylation	LSEKLEQSEAQLGRG HHHHHHHHHHHHCCC	26.06	20068231
282	Methylation	QSEAQLGRGSFMLGL HHHHHHCCCCHHHCC	46.29	-
284	Phosphorylation	EAQLGRGSFMLGLET HHHHCCCCHHHCCCC	13.21	30108239
286	Sulfoxidation	QLGRGSFMLGLETHD HHCCCCHHHCCCCCC	2.88	21406390
291	Phosphorylation	SFMLGLETHDRKSED CHHHCCCCCCCCCHH	33.83	-
294	Methylation	LGLETHDRKSEDKLA HCCCCCCCCCHHHHH	36.47	-
295	Methylation	GLETHDRKSEDKLAK CCCCCCCCCHHHHHH	65.34	-
304	Phosphorylation	EDKLAKATRDSCKTT HHHHHHHHHHHHHHH	34.01	-
307	Phosphorylation	LAKATRDSCKTTIEA HHHHHHHHHHHHHHH	17.77	-
309	Ubiquitination	KATRDSCKTTIEAIH HHHHHHHHHHHHHHH	53.29	-
310	Phosphorylation	ATRDSCKTTIEAIHG HHHHHHHHHHHHHHH	37.02	-
320	Phosphorylation	EAIHGLMSQVIKDKL HHHHHHHHHHHHHHH	26.74	-
324	Ubiquitination	GLMSQVIKDKLFNQI HHHHHHHHHHHHHCC	50.37	-
326	Ubiquitination	MSQVIKDKLFNQINI HHHHHHHHHHHCCCC	50.40	-
326	Acetylation	MSQVIKDKLFNQINI HHHHHHHHHHHCCCC	50.40	87811
334	Phosphorylation	LFNQINIS------- HHHCCCCC-------	29.67	28348404

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
201	S	Phosphorylation	Kinase	IKKA	O15111	PSP
201	S	Phosphorylation	Kinase	IKKB	O14920	PSP
205	T	Phosphorylation	Kinase	IKKA	O15111	PSP
205	T	Phosphorylation	Kinase	IKKB	O14920	PSP
320	S	Phosphorylation	Kinase	ATM	Q13315	PSP
-	K	Ubiquitination	E3 ubiquitin ligase	DDB1	Q16531	PMID:23357576

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CSN5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CSN5_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
S10A7_HUMAN	S100A7	physical	12702588
UCHL1_HUMAN	UCHL1	physical	12082530
CDN1B_HUMAN	CDKN1B	physical	12082530
JUN_HUMAN	JUN	physical	8837781
SMAD4_HUMAN	SMAD4	physical	11818334
ALR_HUMAN	GFER	physical	11709497
SP130_HUMAN	SAP130	physical	18173839
P53_HUMAN	TP53	physical	17879958
MDM2_HUMAN	MDM2	physical	17879958
ERCC8_HUMAN	ERCC8	physical	19615732
DDB2_HUMAN	DDB2	physical	19615732
CSN1_HUMAN	GPS1	physical	19615732
NEDD8_HUMAN	NEDD8	physical	19615732
SKP2_HUMAN	SKP2	physical	19615732
UCHL3_HUMAN	UCHL3	physical	19615732
CUL4B_HUMAN	CUL4B	physical	19615732
CUL4A_HUMAN	CUL4A	physical	19615732
CUL3_HUMAN	CUL3	physical	19615732
CUL2_HUMAN	CUL2	physical	19615732
CUL1_HUMAN	CUL1	physical	19615732
CSN3_HUMAN	COPS3	physical	19615732
CSN2_HUMAN	COPS2	physical	19615732
LRC14_HUMAN	LRRC14	physical	19615732
DCAF1_HUMAN	VPRBP	physical	19615732
CSN8_HUMAN	COPS8	physical	19615732
CSN6_HUMAN	COPS6	physical	19615732
KLH18_HUMAN	KLHL18	physical	19615732
DCAF4_HUMAN	DCAF4	physical	19615732
FBX22_HUMAN	FBXO22	physical	19615732
CSN7A_HUMAN	COPS7A	physical	19615732
CSN4_HUMAN	COPS4	physical	19615732
KLH24_HUMAN	KLHL24	physical	19615732
BTBD2_HUMAN	BTBD2	physical	19615732
KLHL9_HUMAN	KLHL9	physical	19615732
CSN7B_HUMAN	COPS7B	physical	19615732
FBX11_HUMAN	FBXO11	physical	19615732
KLH15_HUMAN	KLHL15	physical	19615732
DCA11_HUMAN	DCAF11	physical	19615732
KLH22_HUMAN	KLHL22	physical	19615732
KLH13_HUMAN	KLHL13	physical	19615732
FBX17_HUMAN	FBXO17	physical	19615732
LLR1_HUMAN	LRR1	physical	19615732
ALR_HUMAN	GFER	physical	14500725
CDN1B_HUMAN	CDKN1B	physical	16951171
TRAF2_HUMAN	TRAF2	physical	16936264
P53_HUMAN	TP53	physical	16936264
TOIP2_HUMAN	TOR1AIP2	physical	19615732
IFG15_HUMAN	TOR1AIP2	physical	19615732
CUL1_HUMAN	CUL1	physical	16036220
BABA2_HUMAN	BRE	physical	19214193
BRCC3_HUMAN	BRCC3	physical	19214193
TERA_HUMAN	VCP	physical	19826004
EDNRA_HUMAN	EDNRA	physical	20034471
CASA1_HUMAN	CSN1S1	physical	18850735
CSN2_HUMAN	COPS2	physical	18850735
CSN3_HUMAN	COPS3	physical	18850735
CSN4_HUMAN	COPS4	physical	18850735
CSN6_HUMAN	COPS6	physical	18850735
CSN7A_HUMAN	COPS7A	physical	18850735
CSN7B_HUMAN	COPS7B	physical	18850735
CSN8_HUMAN	COPS8	physical	18850735
ABCA1_HUMAN	ABCA1	physical	19268428
CAR11_HUMAN	CARD11	physical	19444310
RACK1_HUMAN	GNB2L1	physical	18624398
MP2K2_HUMAN	MAP2K2	physical	18624398
ATRN_HUMAN	ATRN	physical	18624398
PLAC8_HUMAN	PLAC8	physical	18624398
PPOX_HUMAN	PPOX	physical	18624398
SHSA5_HUMAN	SHISA5	physical	18624398
UBP14_HUMAN	USP14	physical	18624398
VTNC_HUMAN	VTN	physical	18624398
GSK3B_HUMAN	GSK3B	physical	19576224
APC_HUMAN	APC	physical	19576224
KC1A_HUMAN	CSNK1A1	physical	19576224
MIS_HUMAN	AMH	physical	17951406
CDN1B_HUMAN	CDKN1B	physical	17951406
BRSK2_HUMAN	BRSK2	physical	22609399
CAND1_HUMAN	CAND1	physical	16861300
DDB2_HUMAN	DDB2	physical	17079684
CDT1_HUMAN	CDT1	physical	17079684
P53_HUMAN	TP53	physical	11285227
CSN6_HUMAN	COPS6	physical	19141280
HIF1A_HUMAN	HIF1A	physical	15082527
VHL_HUMAN	VHL	physical	15082527
CUL1_HUMAN	CUL1	physical	22767593
CUL1_HUMAN	CUL1	physical	22013077
ABCAA_HUMAN	ABCA10	physical	21145461
ABCF1_HUMAN	ABCF1	physical	21145461
ABTB2_HUMAN	ABTB2	physical	21145461
THIL_HUMAN	ACAT1	physical	21145461
PPAC_HUMAN	ACP1	physical	21145461
ACBG2_HUMAN	ACSBG2	physical	21145461
ACTA_HUMAN	ACTA2	physical	21145461
ACTB_HUMAN	ACTB	physical	21145461
ACTBL_HUMAN	ACTBL2	physical	21145461
ACTZ_HUMAN	ACTR1A	physical	21145461
GDE_HUMAN	AGL	physical	21145461
SAHH_HUMAN	AHCY	physical	21145461
AIFM1_HUMAN	AIFM1	physical	21145461
AIMP1_HUMAN	AIMP1	physical	21145461
AKAP8_HUMAN	AKAP8	physical	21145461
ALDOC_HUMAN	ALDOC	physical	21145461
AMRA1_HUMAN	AMBRA1	physical	21145461
AMPD1_HUMAN	AMPD1	physical	21145461
ANC2_HUMAN	ANAPC2	physical	21145461
APC7_HUMAN	ANAPC7	physical	21145461
ANR12_HUMAN	ANKRD12	physical	21145461
AP1B1_HUMAN	AP1B1	physical	21145461
TINAL_HUMAN	TINAGL1	physical	21145461
ASB6_HUMAN	ASB6	physical	21145461
ASNS_HUMAN	ASNS	physical	21145461
GDNF_HUMAN	GDNF	physical	21145461
AT1A4_HUMAN	ATP1A4	physical	21145461
BAG4_HUMAN	BAG4	physical	21145461
BLM_HUMAN	BLM	physical	21145461
BLMH_HUMAN	BLMH	physical	21145461
BRWD1_HUMAN	BRWD1	physical	21145461
BTBD1_HUMAN	BTBD1	physical	21145461
BTBD2_HUMAN	BTBD2	physical	21145461
BTBD9_HUMAN	BTBD9	physical	21145461
BUB3_HUMAN	BUB3	physical	21145461
BYST_HUMAN	BYSL	physical	21145461
CJ055_HUMAN	C10orf55	physical	21145461
CK070_HUMAN	C11orf70	physical	21145461
CN166_HUMAN	C14orf166	physical	21145461
C1QBP_HUMAN	C1QBP	physical	21145461
TRM1L_HUMAN	TRMT1L	physical	21145461
RTCB_HUMAN	RTCB	physical	21145461
UNC80_HUMAN	UNC80	physical	21145461
DCA16_HUMAN	DCAF16	physical	21145461
YAED1_HUMAN	YAE1D1	physical	21145461
CG050_HUMAN	C7orf50	physical	21145461
DFFB_HUMAN	DFFB	physical	21145461
CALL5_HUMAN	CALML5	physical	21145461
CAMKV_HUMAN	CAMKV	physical	21145461
CAND1_HUMAN	CAND1	physical	21145461
CAPR1_HUMAN	CAPRIN1	physical	21145461
CARM1_HUMAN	CARM1	physical	21145461
CBR1_HUMAN	CBR1	physical	21145461
KAT3_HUMAN	CCBL2	physical	21145461
CFA58_HUMAN	CFAP58	physical	21145461
CCD47_HUMAN	CCDC47	physical	21145461
CCNA1_HUMAN	CCNA1	physical	21145461
CCNA2_HUMAN	CCNA2	physical	21145461
CCPG1_HUMAN	CCPG1	physical	21145461
TCPB_HUMAN	CCT2	physical	21145461
TCPQ_HUMAN	CCT8	physical	21145461
DPOD1_HUMAN	POLD1	physical	21145461
CDC20_HUMAN	CDC20	physical	21145461
CDK2_HUMAN	CDK2	physical	21145461
CDK3_HUMAN	CDK3	physical	21145461
CDK4_HUMAN	CDK4	physical	21145461
CDN2A_HUMAN	CDKN2A	physical	21145461
ARF_HUMAN	CDKN2A	physical	21145461
CHK1_HUMAN	CHEK1	physical	21145461
CIRBP_HUMAN	CIRBP	physical	21145461
CKAP4_HUMAN	CKAP4	physical	21145461
CKS1_HUMAN	CKS1B	physical	21145461
CLCA_HUMAN	CLTA	physical	21145461
CLH1_HUMAN	CLTC	physical	21145461
CLH2_HUMAN	CLTCL1	physical	21145461
CNTN4_HUMAN	CNTN4	physical	21145461
CSN2_HUMAN	COPS2	physical	21145461
CSN3_HUMAN	COPS3	physical	21145461
CSN4_HUMAN	COPS4	physical	21145461
CSN5_HUMAN	COPS5	physical	21145461
CSN6_HUMAN	COPS6	physical	21145461
CSN7A_HUMAN	COPS7A	physical	21145461
CSN7B_HUMAN	COPS7B	physical	21145461
CSN8_HUMAN	COPS8	physical	21145461
CPNE2_HUMAN	CPNE2	physical	21145461
CPNE7_HUMAN	CPNE7	physical	21145461
CRBN_HUMAN	CRBN	physical	21145461
LC7L3_HUMAN	LUC7L3	physical	21145461
YBOX3_HUMAN	YBX3	physical	21145461
CSDE1_HUMAN	CSDE1	physical	21145461
CTNA1_HUMAN	CTNNA1	physical	21145461
PYRG1_HUMAN	CTPS1	physical	21145461
CUL1_HUMAN	CUL1	physical	21145461
CUL2_HUMAN	CUL2	physical	21145461
CUL3_HUMAN	CUL3	physical	21145461
CUL4A_HUMAN	CUL4A	physical	21145461
CUL4B_HUMAN	CUL4B	physical	21145461
CUL5_HUMAN	CUL5	physical	21145461
CXCL2_HUMAN	CXCL2	physical	21145461
DLGP3_HUMAN	DLGAP3	physical	21145461
DAZP1_HUMAN	DAZAP1	physical	21145461
DCD_HUMAN	DCD	physical	21145461
PCD23_HUMAN	DCHS2	physical	21145461
DDA1_HUMAN	DDA1	physical	21145461
DDB1_HUMAN	DDB1	physical	21145461
DDB2_HUMAN	DDB2	physical	21145461
DDX1_HUMAN	DDX1	physical	21145461
DDX17_HUMAN	DDX17	physical	21145461
DDX18_HUMAN	DDX18	physical	21145461
DD19B_HUMAN	DDX19B	physical	21145461
DDX20_HUMAN	DDX20	physical	21145461
DDX56_HUMAN	DDX56	physical	21145461
DDX3X_HUMAN	DDX3X	physical	21145461
DDX5_HUMAN	DDX5	physical	21145461
DDX52_HUMAN	DDX52	physical	21145461
DDX6_HUMAN	DDX6	physical	21145461
DB127_HUMAN	DEFB127	physical	21145461
DEK_HUMAN	DEK	physical	21145461
DHX15_HUMAN	DHX15	physical	21145461
DHX29_HUMAN	DHX29	physical	21145461
DHX30_HUMAN	DHX30	physical	21145461
DHX36_HUMAN	DHX36	physical	21145461
DHX57_HUMAN	DHX57	physical	21145461
DHX9_HUMAN	DHX9	physical	21145461
ODP2_HUMAN	DLAT	physical	21145461
DYH2_HUMAN	DNAH2	physical	21145461
DNJA1_HUMAN	DNAJA1	physical	21145461
DNJA2_HUMAN	DNAJA2	physical	21145461
DJC10_HUMAN	DNAJC10	physical	21145461
DNJC9_HUMAN	DNAJC9	physical	21145461
DNM1L_HUMAN	DNM1L	physical	21145461
REQU_HUMAN	DPF2	physical	21145461
DSG1_HUMAN	DSG1	physical	21145461
DESP_HUMAN	DSP	physical	21145461
DTL_HUMAN	DTL	physical	21145461
PTPM1_HUMAN	PTPMT1	physical	21145461
DYHC1_HUMAN	DYNC1H1	physical	21145461
EBP2_HUMAN	EBNA1BP2	physical	21145461
ECSCR_HUMAN	ECSCR	physical	21145461
EF1A1_HUMAN	EEF1A1	physical	21145461
EF1A2_HUMAN	EEF1A2	physical	21145461
EF1G_HUMAN	EEF1G	physical	21145461
EF2_HUMAN	EEF2	physical	21145461
MICU2_HUMAN	MICU2	physical	21145461
U5S1_HUMAN	EFTUD2	physical	21145461
EHBP1_HUMAN	EHBP1	physical	21145461
AGO1_HUMAN	AGO1	physical	21145461
AGO2_HUMAN	AGO2	physical	21145461
IF2A_HUMAN	EIF2S1	physical	21145461
IF4A1_HUMAN	EIF4A1	physical	21145461
IF5A1_HUMAN	EIF5A	physical	21145461
RNZ2_HUMAN	ELAC2	physical	21145461
ELAV1_HUMAN	ELAVL1	physical	21145461
ENOA_HUMAN	ENO1	physical	21145461
SYEP_HUMAN	EPRS	physical	21145461
ERCC8_HUMAN	ERCC8	physical	21145461
EWS_HUMAN	EWSR1	physical	21145461
EXOS9_HUMAN	EXOSC9	physical	21145461
RAM_HUMAN	FAM103A1	physical	21145461
F1142_HUMAN	FAM114A2	physical	21145461
FA83H_HUMAN	FAM83H	physical	21145461
FA98A_HUMAN	FAM98A	physical	21145461
FA98B_HUMAN	FAM98B	physical	21145461
UBIM_HUMAN	FAU	physical	21145461
FBRL_HUMAN	FBL	physical	21145461
FXL14_HUMAN	FBXL14	physical	21145461
FXL18_HUMAN	FBXL18	physical	21145461
FBXL5_HUMAN	FBXL5	physical	21145461
FBX10_HUMAN	FBXO10	physical	21145461
FBX11_HUMAN	FBXO11	physical	21145461
FBX17_HUMAN	FBXO17	physical	21145461
FBX21_HUMAN	FBXO21	physical	21145461
FBX22_HUMAN	FBXO22	physical	21145461
FBX3_HUMAN	FBXO3	physical	21145461
FBX31_HUMAN	FBXO31	physical	21145461
FBX44_HUMAN	FBXO44	physical	21145461
FBX46_HUMAN	FBXO46	physical	21145461
FBX7_HUMAN	FBXO7	physical	21145461
FBX9_HUMAN	FBXO9	physical	21145461
FBW1B_HUMAN	FBXW11	physical	21145461
FBXW9_HUMAN	FBXW9	physical	21145461
HEMH_HUMAN	FECH	physical	21145461
FEM1B_HUMAN	FEM1B	physical	21145461
FEM1C_HUMAN	FEM1C	physical	21145461
FIGN_HUMAN	FIGN	physical	21145461
FIP1_HUMAN	FIP1L1	physical	21145461
FILA2_HUMAN	FLG2	physical	21145461
SPB1_HUMAN	FTSJ3	physical	21145461
FUBP1_HUMAN	FUBP1	physical	21145461
FUBP3_HUMAN	FUBP3	physical	21145461
FUS_HUMAN	FUS	physical	21145461
FXR1_HUMAN	FXR1	physical	21145461
G3BP1_HUMAN	G3BP1	physical	21145461
G3BP2_HUMAN	G3BP2	physical	21145461
G45IP_HUMAN	GADD45GIP1	physical	21145461
GLT13_HUMAN	GALNT13	physical	21145461
G3P_HUMAN	GAPDH	physical	21145461
GGH_HUMAN	GGH	physical	21145461
RACK1_HUMAN	GNB2L1	physical	21145461
GNL3_HUMAN	GNL3	physical	21145461
CSN1_HUMAN	GPS1	physical	21145461
GRWD1_HUMAN	GRWD1	physical	21145461
GSTP1_HUMAN	GSTP1	physical	21145461
GTPB1_HUMAN	GTPBP1	physical	21145461
NOG1_HUMAN	GTPBP4	physical	21145461
GYS1_HUMAN	GYS1	physical	21145461
HAT1_HUMAN	HAT1	physical	21145461
VIGLN_HUMAN	HDLBP	physical	21145461
H12_HUMAN	HIST1H1C	physical	21145461
H2B2E_HUMAN	HIST2H2BE	physical	21145461
ROA0_HUMAN	HNRNPA0	physical	21145461
ROA1_HUMAN	HNRNPA1	physical	21145461
ROA2_HUMAN	HNRNPA2B1	physical	21145461
ROA3_HUMAN	HNRNPA3	physical	21145461
ROAA_HUMAN	HNRNPAB	physical	21145461
HNRPC_HUMAN	HNRNPC	physical	21145461
HNRC1_HUMAN	HNRNPCL1	physical	21145461
HNRPD_HUMAN	HNRNPD	physical	21145461
HNRPF_HUMAN	HNRNPF	physical	21145461
HNRH1_HUMAN	HNRNPH1	physical	21145461
HNRH3_HUMAN	HNRNPH3	physical	21145461
HNRPK_HUMAN	HNRNPK	physical	21145461
HNRPL_HUMAN	HNRNPL	physical	21145461
HNRPM_HUMAN	HNRNPM	physical	21145461
HNRPR_HUMAN	HNRNPR	physical	21145461
HNRPU_HUMAN	HNRNPU	physical	21145461
HNRL1_HUMAN	HNRNPUL1	physical	21145461
HNRL2_HUMAN	HNRNPUL2	physical	21145461
HNRDL_HUMAN	HNRNPDL	physical	21145461
HXA10_HUMAN	HOXA10	physical	21145461
HORN_HUMAN	HRNR	physical	21145461
DHI1L_HUMAN	HSD11B1L	physical	21145461
HCD2_HUMAN	HSD17B10	physical	21145461
HS90A_HUMAN	HSP90AA1	physical	21145461
ENPL_HUMAN	HSP90B1	physical	21145461
HS71L_HUMAN	HSPA1L	physical	21145461
HSP74_HUMAN	HSPA4	physical	21145461
GRP78_HUMAN	HSPA5	physical	21145461
HSP76_HUMAN	HSPA6	physical	21145461
HSP7C_HUMAN	HSPA8	physical	21145461
GRP75_HUMAN	HSPA9	physical	21145461
HSPB1_HUMAN	HSPB1	physical	21145461
CH60_HUMAN	HSPD1	physical	21145461
SYIC_HUMAN	IARS	physical	21145461
TOIP2_HUMAN	TOR1AIP2	physical	21145461
IFG15_HUMAN	TOR1AIP2	physical	21145461
IF2B1_HUMAN	IGF2BP1	physical	21145461
IF2B3_HUMAN	IGF2BP3	physical	21145461
ILF2_HUMAN	ILF2	physical	21145461
ILF3_HUMAN	ILF3	physical	21145461
ILK_HUMAN	ILK	physical	21145461
TCPD_HUMAN	CCT4	physical	21145461
IMDH2_HUMAN	IMPDH2	physical	21145461
IRS4_HUMAN	IRS4	physical	21145461
ISL1_HUMAN	ISL1	physical	21145461
ISL2_HUMAN	ISL2	physical	21145461
JUND_HUMAN	JUND	physical	21145461
PLAK_HUMAN	JUP	physical	21145461
SYK_HUMAN	KARS	physical	21145461
KBTB4_HUMAN	KBTBD4	physical	21145461
KBTB6_HUMAN	KBTBD6	physical	21145461
BACD3_HUMAN	KCTD10	physical	21145461
KCD18_HUMAN	KCTD18	physical	21145461
KCTD3_HUMAN	KCTD3	physical	21145461
KCTD6_HUMAN	KCTD6	physical	21145461
KHK_HUMAN	KHK	physical	21145461
FUBP2_HUMAN	KHSRP	physical	21145461
CIPC_HUMAN	CIPC	physical	21145461
CCAR2_HUMAN	CCAR2	physical	21145461
KLH42_HUMAN	KLHL42	physical	21145461
KLH12_HUMAN	KLHL12	physical	21145461
KLH13_HUMAN	KLHL13	physical	21145461
KLH15_HUMAN	KLHL15	physical	21145461
KLH18_HUMAN	KLHL18	physical	21145461
KLH21_HUMAN	KLHL21	physical	21145461
KLH22_HUMAN	KLHL22	physical	21145461
KLH23_HUMAN	KLHL23	physical	21145461
KLH24_HUMAN	KLHL24	physical	21145461
KLH26_HUMAN	KLHL26	physical	21145461
KLH36_HUMAN	KLHL36	physical	21145461
KLHL8_HUMAN	KLHL8	physical	21145461
KLHL9_HUMAN	KLHL9	physical	21145461
IMA5_HUMAN	KPNA1	physical	21145461
IMA1_HUMAN	KPNA2	physical	21145461
IMB1_HUMAN	KPNB1	physical	21145461
K2C1_HUMAN	KRT1	physical	21145461
K1C10_HUMAN	KRT10	physical	21145461
K1C13_HUMAN	KRT13	physical	21145461
K1C14_HUMAN	KRT14	physical	21145461
K1C16_HUMAN	KRT16	physical	21145461
K1C17_HUMAN	KRT17	physical	21145461
K22E_HUMAN	KRT2	physical	21145461
K1C24_HUMAN	KRT24	physical	21145461
K2C3_HUMAN	KRT3	physical	21145461
K2C5_HUMAN	KRT5	physical	21145461
K2C6A_HUMAN	KRT6A	physical	21145461
K2C6B_HUMAN	KRT6B	physical	21145461
K2C6C_HUMAN	KRT6C	physical	21145461
K2C71_HUMAN	KRT71	physical	21145461
K2C75_HUMAN	KRT75	physical	21145461
K22O_HUMAN	KRT76	physical	21145461
K2C78_HUMAN	KRT78	physical	21145461
K2C80_HUMAN	KRT80	physical	21145461
K1C9_HUMAN	KRT9	physical	21145461
LARP1_HUMAN	LARP1	physical	21145461
LAR4B_HUMAN	LARP4B	physical	21145461
LDHB_HUMAN	LDHB	physical	21145461
LG3BP_HUMAN	LGALS3BP	physical	21145461
LEG7_HUMAN	LGALS7	physical	21145461
LN28B_HUMAN	LIN28B	physical	21145461
LRCH2_HUMAN	LRCH2	physical	21145461
LRC14_HUMAN	LRRC14	physical	21145461
LRC47_HUMAN	LRRC47	physical	21145461
LSM12_HUMAN	LSM12	physical	21145461
LC7L2_HUMAN	LUC7L2	physical	21145461
LYAR_HUMAN	LYAR	physical	21145461
MAGD2_HUMAN	MAGED2	physical	21145461
M4K1_HUMAN	MAP4K1	physical	21145461
MAPK2_HUMAN	MAPKAPK2	physical	21145461
METK2_HUMAN	MAT2A	physical	21145461
MATR3_HUMAN	MATR3	physical	21145461
MCM3_HUMAN	MCM3	physical	21145461
MCM7_HUMAN	MCM7	physical	21145461
MDHM_HUMAN	MDH2	physical	21145461
MNX1_HUMAN	MNX1	physical	21145461
MOV10_HUMAN	MOV10	physical	21145461
RM11_HUMAN	MRPL11	physical	21145461
RM15_HUMAN	MRPL15	physical	21145461
RM43_HUMAN	MRPL43	physical	21145461
RM49_HUMAN	MRPL49	physical	21145461
RT11_HUMAN	MRPS11	physical	21145461
RT15_HUMAN	MRPS15	physical	21145461
RT22_HUMAN	MRPS22	physical	21145461
RT23_HUMAN	MRPS23	physical	21145461
RT25_HUMAN	MRPS25	physical	21145461
RT27_HUMAN	MRPS27	physical	21145461
C1TM_HUMAN	MTHFD1L	physical	21145461
MBB1A_HUMAN	MYBBP1A	physical	21145461
CSN9_HUMAN	MYEOV2	physical	21145461
MYLK4_HUMAN	MYLK4	physical	21145461
MYNN_HUMAN	MYNN	physical	21145461
MYOZ1_HUMAN	MYOZ1	physical	21145461
NP1L1_HUMAN	NAP1L1	physical	21145461
NCBP1_HUMAN	NCBP1	physical	21145461
NUCL_HUMAN	NCL	physical	21145461
NDUV1_HUMAN	NDUFV1	physical	21145461
NEDD8_HUMAN	NEDD8	physical	21145461
NFKB1_HUMAN	NFKB1	physical	21145461
NKRF_HUMAN	NKRF	physical	21145461
NONO_HUMAN	NONO	physical	21145461
NOP16_HUMAN	NOP16	physical	21145461
NOP2_HUMAN	NOP2	physical	21145461
NOP56_HUMAN	NOP56	physical	21145461
NPM_HUMAN	NPM1	physical	21145461
NQO2_HUMAN	NQO2	physical	21145461
NSUN2_HUMAN	NSUN2	physical	21145461
8ODP_HUMAN	NUDT1	physical	21145461
TIRR_HUMAN	NUDT16L1	physical	21145461
NUFP2_HUMAN	NUFIP2	physical	21145461
NU155_HUMAN	NUP155	physical	21145461
NUPL2_HUMAN	NUPL2	physical	21145461
NXF1_HUMAN	NXF1	physical	21145461
PABP1_HUMAN	PABPC1	physical	21145461
PABP4_HUMAN	PABPC4	physical	21145461
PABP2_HUMAN	PABPN1	physical	21145461
PARP1_HUMAN	PARP1	physical	21145461
PHS_HUMAN	PCBD1	physical	21145461
PCBP1_HUMAN	PCBP1	physical	21145461
PCBP2_HUMAN	PCBP2	physical	21145461
PIMT_HUMAN	PCMT1	physical	21145461
PDE12_HUMAN	PDE12	physical	21145461
PDE6D_HUMAN	PDE6D	physical	21145461
ODPAT_HUMAN	PDHA2	physical	21145461
PDIA6_HUMAN	PDIA6	physical	21145461
PDXK_HUMAN	PDXK	physical	21145461
PFKAP_HUMAN	PFKP	physical	21145461
PGAM5_HUMAN	PGAM5	physical	21145461
PGK1_HUMAN	PGK1	physical	21145461
PGRC1_HUMAN	PGRMC1	physical	21145461
PHRF1_HUMAN	PHRF1	physical	21145461
KPYM_HUMAN	PKM	physical	21145461
PLK1_HUMAN	PLK1	physical	21145461
PLOD1_HUMAN	PLOD1	physical	21145461
POF1B_HUMAN	POF1B	physical	21145461
RPB3_HUMAN	POLR2C	physical	21145461
RPAB1_HUMAN	POLR2E	physical	21145461
POP1_HUMAN	POP1	physical	21145461
PPIA_HUMAN	PPIA	physical	21145461
LLR1_HUMAN	LRR1	physical	21145461
PP1G_HUMAN	PPP1CC	physical	21145461
PR15A_HUMAN	PPP1R15A	physical	21145461
PRDX1_HUMAN	PRDX1	physical	21145461
PRDX3_HUMAN	PRDX3	physical	21145461
PRKDC_HUMAN	PRKDC	physical	21145461
PRP19_HUMAN	PRPF19	physical	21145461
PRP31_HUMAN	PRPF31	physical	21145461
PRP39_HUMAN	PRPF39	physical	21145461
PR40A_HUMAN	PRPF40A	physical	21145461
PRPS3_HUMAN	PRPS1L1	physical	21145461
KPRA_HUMAN	PRPSAP1	physical	21145461
KPRB_HUMAN	PRPSAP2	physical	21145461
PSA7_HUMAN	PSMA7	physical	21145461
PSME4_HUMAN	PSME4	physical	21145461
PTBP1_HUMAN	PTBP1	physical	21145461
PUF60_HUMAN	PUF60	physical	21145461
PWP1_HUMAN	PWP1	physical	21145461
DHPR_HUMAN	QDPR	physical	21145461
QPCT_HUMAN	QPCT	physical	21145461
RBM14_HUMAN	RBM14	physical	21145461
RBM3_HUMAN	RBM3	physical	21145461
RBM39_HUMAN	RBM39	physical	21145461
RBM4_HUMAN	RBM4	physical	21145461
RBM42_HUMAN	RBM42	physical	21145461
RBM5_HUMAN	RBM5	physical	21145461
RMXL2_HUMAN	RBMXL2	physical	21145461
RCBT1_HUMAN	RCBTB1	physical	21145461
RELN_HUMAN	RELN	physical	21145461
RFC2_HUMAN	RFC2	physical	21145461
RHBT1_HUMAN	RHOBTB1	physical	21145461
RN138_HUMAN	RNF138	physical	21145461
MCES_HUMAN	RNMT	physical	21145461
RNPS1_HUMAN	RNPS1	physical	21145461
RL10_HUMAN	RPL10	physical	21145461
RL10A_HUMAN	RPL10A	physical	21145461
RL10L_HUMAN	RPL10L	physical	21145461
RL11_HUMAN	RPL11	physical	21145461
RL12_HUMAN	RPL12	physical	21145461
RL13_HUMAN	RPL13	physical	21145461
RL14_HUMAN	RPL14	physical	21145461
RL15_HUMAN	RPL15	physical	21145461
RL17_HUMAN	RPL17	physical	21145461
RL18_HUMAN	RPL18	physical	21145461
RL18A_HUMAN	RPL18A	physical	21145461
RL19_HUMAN	RPL19	physical	21145461
RL21_HUMAN	RPL21	physical	21145461
RL22_HUMAN	RPL22	physical	21145461
RL23_HUMAN	RPL23	physical	21145461
RL23A_HUMAN	RPL23A	physical	21145461
RL24_HUMAN	RPL24	physical	21145461
RL26L_HUMAN	RPL26L1	physical	21145461
RL27_HUMAN	RPL27	physical	21145461
RL27A_HUMAN	RPL27A	physical	21145461
RL28_HUMAN	RPL28	physical	21145461
RL3_HUMAN	RPL3	physical	21145461
RL30_HUMAN	RPL30	physical	21145461
RL31_HUMAN	RPL31	physical	21145461
RL35_HUMAN	RPL35	physical	21145461
HNRH2_HUMAN	HNRNPH2	physical	21145461
RL37A_HUMAN	RPL37A	physical	21145461
RL38_HUMAN	RPL38	physical	21145461
RL4_HUMAN	RPL4	physical	21145461
RL5_HUMAN	RPL5	physical	21145461
RL6_HUMAN	RPL6	physical	21145461
RL7_HUMAN	RPL7	physical	21145461
RL8_HUMAN	RPL8	physical	21145461
RL9_HUMAN	RPL9	physical	21145461
RLA0_HUMAN	RPLP0	physical	21145461
RLA1_HUMAN	RPLP1	physical	21145461
RLA2_HUMAN	RPLP2	physical	21145461
RPN1_HUMAN	RPN1	physical	21145461
RS10_HUMAN	RPS10	physical	21145461
RS11_HUMAN	RPS11	physical	21145461
RS13_HUMAN	RPS13	physical	21145461
RS14_HUMAN	RPS14	physical	21145461
RS15_HUMAN	RPS15	physical	21145461
RS15A_HUMAN	RPS15A	physical	21145461
RS16_HUMAN	RPS16	physical	21145461
RS17_HUMAN	RPS17	physical	21145461
RS18_HUMAN	RPS18	physical	21145461
RS19_HUMAN	RPS19	physical	21145461
RS2_HUMAN	RPS2	physical	21145461
RS20_HUMAN	RPS20	physical	21145461
RS21_HUMAN	RPS21	physical	21145461
RS23_HUMAN	RPS23	physical	21145461
RS24_HUMAN	RPS24	physical	21145461
RS25_HUMAN	RPS25	physical	21145461
RS27_HUMAN	RPS27	physical	21145461
RS3_HUMAN	RPS3	physical	21145461
RS3A_HUMAN	RPS3A	physical	21145461
RS4X_HUMAN	RPS4X	physical	21145461
RS6_HUMAN	RPS6	physical	21145461
RS7_HUMAN	RPS7	physical	21145461
RS8_HUMAN	RPS8	physical	21145461
RS9_HUMAN	RPS9	physical	21145461
RSSA_HUMAN	RPSA	physical	21145461
RIR1_HUMAN	RRM1	physical	21145461
RRP12_HUMAN	RRP12	physical	21145461
RRP15_HUMAN	RRP15	physical	21145461
RL1D1_HUMAN	RSL1D1	physical	21145461
RUVB1_HUMAN	RUVBL1	physical	21145461
S10A8_HUMAN	S100A8	physical	21145461
S10A9_HUMAN	S100A9	physical	21145461
SAFB2_HUMAN	SAFB2	physical	21145461
SDHA_HUMAN	SDHA	physical	21145461
SDHB_HUMAN	SDHB	physical	21145461
SEH1_HUMAN	SEH1L	physical	21145461
SENP6_HUMAN	SENP6	physical	21145461
SPB3_HUMAN	SERPINB3	physical	21145461
SPB4_HUMAN	SERPINB4	physical	21145461
SF3A3_HUMAN	SF3A3	physical	21145461
SF3B1_HUMAN	SF3B1	physical	21145461
SF3B3_HUMAN	SF3B3	physical	21145461
SF3B4_HUMAN	SF3B4	physical	21145461
SFPQ_HUMAN	SFPQ	physical	21145461
SRSF1_HUMAN	SRSF1	physical	21145461
SRSF2_HUMAN	SRSF2	physical	21145461
SRSF3_HUMAN	SRSF3	physical	21145461
SRSF5_HUMAN	SRSF5	physical	21145461
SRSF6_HUMAN	SRSF6	physical	21145461
SRSF7_HUMAN	SRSF7	physical	21145461
SHKB1_HUMAN	SHKBP1	physical	21145461
SK2L2_HUMAN	SKIV2L2	physical	21145461
SKP1_HUMAN	SKP1	physical	21145461
SKP2_HUMAN	SKP2	physical	21145461
MPCP_HUMAN	SLC25A3	physical	21145461
ADT1_HUMAN	SLC25A4	physical	21145461
ADT2_HUMAN	SLC25A5	physical	21145461
ADT3_HUMAN	SLC25A6	physical	21145461
SN12L_HUMAN	SLFN12L	physical	21145461
SMCA4_HUMAN	SMARCA4	physical	21145461
SNF5_HUMAN	SMARCB1	physical	21145461
SMC3_HUMAN	SMC3	physical	21145461
RL32_HUMAN	RPL32	physical	21145461
U520_HUMAN	SNRNP200	physical	21145461
RU17_HUMAN	SNRNP70	physical	21145461
SNRPA_HUMAN	SNRPA	physical	21145461
RSMB_HUMAN	SNRPB	physical	21145461
RU1C_HUMAN	SNRPC	physical	21145461
SMD1_HUMAN	SNRPD1	physical	21145461
SMD2_HUMAN	SNRPD2	physical	21145461
SMD3_HUMAN	SNRPD3	physical	21145461
RUXE_HUMAN	SNRPE	physical	21145461
RUXF_HUMAN	SNRPF	physical	21145461
RUXG_HUMAN	SNRPG	physical	21145461
SNX9_HUMAN	SNX9	physical	21145461
SORL_HUMAN	SORL1	physical	21145461
SPTN1_HUMAN	SPTAN1	physical	21145461
SPTB2_HUMAN	SPTBN1	physical	21145461
SR140_HUMAN	U2SURP	physical	21145461
SRP14_HUMAN	SRP14	physical	21145461
SRPK1_HUMAN	SRPK1	physical	21145461
SRRM2_HUMAN	SRRM2	physical	21145461
LA_HUMAN	SSB	physical	21145461
SSBP_HUMAN	SSBP1	physical	21145461
SSRD_HUMAN	SSR4	physical	21145461
SSRP1_HUMAN	SSRP1	physical	21145461
STAU2_HUMAN	STAU2	physical	21145461
TTC5_HUMAN	TTC5	physical	21145461
STRBP_HUMAN	STRBP	physical	21145461
HNRPQ_HUMAN	SYNCRIP	physical	21145461
RBP56_HUMAN	TAF15	physical	21145461
TBL2_HUMAN	TBL2	physical	21145461
ELOC_HUMAN	TCEB1	physical	21145461
ELOB_HUMAN	TCEB2	physical	21145461
TCPA_HUMAN	TCP1	physical	21145461
TFAM_HUMAN	TFAM	physical	21145461
TFG_HUMAN	TFG	physical	21145461
THOC4_HUMAN	ALYREF	physical	21145461
TIA1_HUMAN	TIA1	physical	21145461
TIAR_HUMAN	TIAL1	physical	21145461
TMC1_HUMAN	TMC1	physical	21145461
TNR6B_HUMAN	TNRC6B	physical	21145461
TOP1_HUMAN	TOP1	physical	21145461
TRA2A_HUMAN	TRA2A	physical	21145461
TRA2B_HUMAN	TRA2B	physical	21145461
TIF1B_HUMAN	TRIM28	physical	21145461
TRM61_HUMAN	TRMT61A	physical	21145461
TP4AP_HUMAN	TRPC4AP	physical	21145461
TTBK2_HUMAN	TTBK2	physical	21145461
TITIN_HUMAN	TTN	physical	21145461
TBA1C_HUMAN	TUBA1C	physical	21145461
TBA4A_HUMAN	TUBA4A	physical	21145461
TBB5_HUMAN	TUBB	physical	21145461
TBB1_HUMAN	TUBB1	physical	21145461
TBB4B_HUMAN	TUBB4B	physical	21145461
EFTU_HUMAN	TUFM	physical	21145461
THIO_HUMAN	TXN	physical	21145461
TYRO3_HUMAN	TYRO3	physical	21145461
U2AF2_HUMAN	U2AF2	physical	21145461
UBA1_HUMAN	UBA1	physical	21145461
UBP2L_HUMAN	UBAP2L	physical	21145461
UBC_HUMAN	UBC	physical	21145461
RENT1_HUMAN	UPF1	physical	21145461
REN3B_HUMAN	UPF3B	physical	21145461
HEM4_HUMAN	UROS	physical	21145461
UBP15_HUMAN	USP15	physical	21145461
UBP7_HUMAN	USP7	physical	21145461
TERA_HUMAN	VCP	physical	21145461
VIME_HUMAN	VIM	physical	21145461
DCAF1_HUMAN	VPRBP	physical	21145461
DCAF4_HUMAN	DCAF4	physical	21145461
DC4L1_HUMAN	DCAF4L1	physical	21145461
DCA11_HUMAN	DCAF11	physical	21145461
DCA12_HUMAN	DCAF12	physical	21145461
DCAF8_HUMAN	DCAF8	physical	21145461
WDR5_HUMAN	WDR5	physical	21145461
WDR61_HUMAN	WDR61	physical	21145461
WIPI2_HUMAN	WIPI2	physical	21145461
XRCC6_HUMAN	XRCC6	physical	21145461
XRN2_HUMAN	XRN2	physical	21145461
YBOX1_HUMAN	YBX1	physical	21145461
YTDC2_HUMAN	YTHDC2	physical	21145461
1433Z_HUMAN	YWHAZ	physical	21145461
ZCCHV_HUMAN	ZC3HAV1	physical	21145461
TUT4_HUMAN	ZCCHC11	physical	21145461
ZFR_HUMAN	ZFR	physical	21145461
ZN185_HUMAN	ZNF185	physical	21145461
ZN302_HUMAN	ZNF302	physical	21145461
ZN554_HUMAN	ZNF554	physical	21145461
ZY11B_HUMAN	ZYG11B	physical	21145461
H2A1B_HUMAN	HIST1H2AE	physical	21145461
H2A1J_HUMAN	HIST1H2AJ	physical	21145461
H2A1_HUMAN	HIST1H2AI	physical	21145461
H4_HUMAN	HIST1H4I	physical	21145461
CSN2_HUMAN	COPS2	physical	10903862
CSN7A_HUMAN	COPS7A	physical	10903862
SMAD7_HUMAN	SMAD7	physical	14993265
SMAD4_HUMAN	SMAD4	physical	14993265
THIO_HUMAN	TXN	physical	15480426
CDN1B_HUMAN	CDKN1B	physical	15480426
CDN1B_HUMAN	CDKN1B	physical	22350412
B2L14_HUMAN	BCL2L14	physical	18006276
MINY3_HUMAN	FAM188A	physical	21499297
ERN1_HUMAN	ERN1	physical	15234121
E2AK3_HUMAN	EIF2AK3	physical	15234121
S10A7_HUMAN	S100A7	physical	15994944
TOP2A_HUMAN	TOP2A	physical	15126503
PRGR_HUMAN	PGR	physical	10722692
NCOA1_HUMAN	NCOA1	physical	10722692
HIF1A_MOUSE	Hif1a	physical	11707426
ESR1_HUMAN	ESR1	physical	15899841
SMAD4_HUMAN	SMAD4	physical	17583730
RAD1_HUMAN	RAD1	physical	17583730
RAD9A_HUMAN	RAD9A	physical	17583730
HUS1_HUMAN	HUS1	physical	17583730
CCDB1_HUMAN	CCNDBP1	physical	15887118
CDN1B_HUMAN	CDKN1B	physical	18285702
TP53B_HUMAN	TP53BP1	physical	16187115
5HT6R_HUMAN	HTR6	physical	20093369
JUN_HUMAN	JUN	physical	20093369
P53_HUMAN	TP53	physical	16624822
CSN1_HUMAN	GPS1	physical	16624822
CSN2_HUMAN	COPS2	physical	16624822
CSN3_HUMAN	COPS3	physical	16624822
CSN4_HUMAN	COPS4	physical	16624822
CSN7B_HUMAN	COPS7B	physical	16624822
RFWD2_HUMAN	RFWD2	physical	19295130
CSN2_HUMAN	COPS2	physical	19295130
CSN3_HUMAN	COPS3	physical	19295130
CSN4_HUMAN	COPS4	physical	19295130
CSN6_HUMAN	COPS6	physical	19295130
CSN7A_HUMAN	COPS7A	physical	19295130
CSN7B_HUMAN	COPS7B	physical	19295130
CSN8_HUMAN	COPS8	physical	19295130
RBX1_HUMAN	RBX1	physical	19295130
CUL2_HUMAN	CUL2	physical	19295130
CUL3_HUMAN	CUL3	physical	19295130
BTBD1_HUMAN	BTBD1	physical	19295130
CUL4A_HUMAN	CUL4A	physical	19295130
CUL4B_HUMAN	CUL4B	physical	19295130
DDB1_HUMAN	DDB1	physical	19295130
DCAF1_HUMAN	VPRBP	physical	19295130
DCA11_HUMAN	DCAF11	physical	19295130
DTL_HUMAN	DTL	physical	19295130
A4_HUMAN	APP	physical	21832049
CSN6_HUMAN	COPS6	physical	22939629
CSN7A_HUMAN	COPS7A	physical	22939629
CSN7B_HUMAN	COPS7B	physical	22939629
CSN5_HUMAN	COPS5	physical	23288897
DTL_HUMAN	DTL	physical	23555860
CSN8_HUMAN	COPS8	physical	23636414
CSN3_HUMAN	COPS3	physical	23636414
IKKB_HUMAN	IKBKB	physical	23636414
CSN9_HUMAN	MYEOV2	physical	23776465
CENPT_HUMAN	CENPT	physical	23926101
CENPW_HUMAN	CENPW	physical	23926101
CSN1_HUMAN	GPS1	physical	23926101
CDK2_HUMAN	CDK2	physical	23926101
OXDD_HUMAN	DDO	physical	21988832
NFKB1_HUMAN	NFKB1	physical	21988832
PRDX2_HUMAN	PRDX2	physical	21988832
SHAN3_HUMAN	SHANK3	physical	21988832
TYK2_HUMAN	TYK2	physical	24043623
PDLI7_HUMAN	PDLIM7	physical	24078030
SMAD4_HUMAN	SMAD4	physical	24078030
ICAL_HUMAN	CAST	physical	22863883
CSN2_HUMAN	COPS2	physical	22863883
CSN3_HUMAN	COPS3	physical	22863883
CSN4_HUMAN	COPS4	physical	22863883
CSN6_HUMAN	COPS6	physical	22863883
CUL1_SCHPO	cul1	physical	24421388
CREB3_HUMAN	CREB3	physical	23583719
CSN5_HUMAN	COPS5	physical	23583719
RANB9_HUMAN	RANBP9	physical	23926111
A4_HUMAN	APP	physical	23926111
LRP1_HUMAN	LRP1	physical	23926111
BACE1_HUMAN	BACE1	physical	23926111
CTNB1_HUMAN	CTNNB1	physical	24882689
SIAH1_HUMAN	SIAH1	physical	24882689
PGH2_HUMAN	PTGS2	physical	17429597
CSN6_HUMAN	COPS6	physical	25144743
NEDD8_HUMAN	NEDD8	physical	25144743
CUL1_HUMAN	CUL1	physical	25144743
OPRM_HUMAN	OPRM1	physical	23840749
CUL1_SCHPO	cul1	physical	11337588
CUL1_HUMAN	CUL1	physical	22956996
CUL2_HUMAN	CUL2	physical	22956996
CUL4A_HUMAN	CUL4A	physical	22956996
CDC53_YEAST	CDC53	physical	22956996
CUL4A_HUMAN	CUL4A	physical	12732143
CUL1_HUMAN	CUL1	physical	19141280
CUL1_HUMAN	CUL1	physical	22959436
CSN8_HUMAN	COPS8	physical	26186194
CSN2_HUMAN	COPS2	physical	26186194
FNIP1_HUMAN	FNIP1	physical	26186194
CSN1_HUMAN	GPS1	physical	26186194
ZNT9_HUMAN	SLC30A9	physical	26186194
CUL4B_HUMAN	CUL4B	physical	26186194
CUL4A_HUMAN	CUL4A	physical	26186194
CSN4_HUMAN	COPS4	physical	26186194
CIPC_HUMAN	CIPC	physical	26186194
CSN3_HUMAN	COPS3	physical	26186194
DDB2_HUMAN	DDB2	physical	26186194
CSN7B_HUMAN	COPS7B	physical	26186194
CSN7A_HUMAN	COPS7A	physical	26186194
BTBD1_HUMAN	BTBD1	physical	26186194
BTBD2_HUMAN	BTBD2	physical	26186194
TPD54_HUMAN	TPD52L2	physical	26186194
CSN4_HUMAN	COPS4	physical	24725084
GCYA3_HUMAN	GUCY1A3	physical	24725084
P53_HUMAN	TP53	physical	24725084
CSN3_HUMAN	COPS3	physical	26344197
CSN4_HUMAN	COPS4	physical	26344197
CSN6_HUMAN	COPS6	physical	26344197
EIF3F_HUMAN	EIF3F	physical	26344197
CSN1_HUMAN	GPS1	physical	26344197
LPP_HUMAN	LPP	physical	26344197
TRIP6_HUMAN	TRIP6	physical	26344197
RENT1_HUMAN	UPF1	physical	26344197
CUL1_HUMAN	CUL1	physical	26265931
CUL4A_HUMAN	CUL4A	physical	27029275
CUL1_HUMAN	CUL1	physical	24973710
CDN1C_HUMAN	CDKN1C	physical	26606000
AHR_HUMAN	AHR	physical	27060206
SMAD4_HUMAN	SMAD4	physical	27060206
CUL1_HUMAN	CUL1	physical	27774986
CSN2_HUMAN	COPS2	physical	28514442
CSN3_HUMAN	COPS3	physical	28514442
CIPC_HUMAN	CIPC	physical	28514442
CSN7A_HUMAN	COPS7A	physical	28514442
BTBD1_HUMAN	BTBD1	physical	28514442
FNIP1_HUMAN	FNIP1	physical	28514442
DDB2_HUMAN	DDB2	physical	28514442
CSN4_HUMAN	COPS4	physical	28514442
CSN1_HUMAN	GPS1	physical	28514442
CUL4B_HUMAN	CUL4B	physical	28514442
BTBD2_HUMAN	BTBD2	physical	28514442
CUL3_HUMAN	CUL3	physical	28514442
CUL4A_HUMAN	CUL4A	physical	28514442
CSN7B_HUMAN	COPS7B	physical	27173435
CDN1B_HUMAN	CDKN1B	physical	28919423

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CSN5_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, AND MASS SPECTROMETRY.	19413330 [Abstract]
"Characterization of the human COP9 signalosome complex using affinitypurification and mass spectrometry."; Fang L., Wang X., Yamoah K., Chen P.L., Pan Z.Q., Huang L.; J. Proteome Res. 7:4914-4925(2008). Cited for: IDENTIFICATION IN THE CSN COMPLEX, CLEAVAGE OF INITIATOR METHIONINE,AND ACETYLATION AT ALA-2.	18850735 [Abstract]
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-47, AND MASS SPECTROMETRY.	19608861 [Abstract]