| UniProt ID | RCBT1_HUMAN | |
|---|---|---|
| UniProt AC | Q8NDN9 | |
| Protein Name | RCC1 and BTB domain-containing protein 1 | |
| Gene Name | RCBTB1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 531 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | May be involved in cell cycle regulation by chromatin remodeling.. | |
| Protein Sequence | MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESLKKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPVYRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 20 | Phosphorylation | LSPQEIASIRKACVF CCHHHHHHHHHHHHC | 28.70 | 24719451 | |
| 67 | Ubiquitination | QSTLVPKKLEGLCGK CCCCCCCHHHCCCCC | 45.78 | - | |
| 173 | Ubiquitination | ANQPTPRKVTNCLHI CCCCCCCCCCCCCHH | 55.40 | - | |
| 283 | Ubiquitination | PAHIMVEKERVVEIA HHEEEEECHHHHEHH | 39.13 | 21906983 | |
| 347 | Phosphorylation | AVSWRLLSVEHEDFL CCEEEECCCCCHHHH | 30.01 | 28348404 | |
| 350 (in isoform 2) | Phosphorylation | - | 37.46 | 19690332 | |
| 361 | Ubiquitination | LTVAESLKKEFDSPE HHHHHHHHHHCCCCC | 60.58 | - | |
| 366 | Phosphorylation | SLKKEFDSPETADLK HHHHHCCCCCCCCEE | 29.92 | 21815630 | |
| 373 | Ubiquitination | SPETADLKFRIDGKY CCCCCCEEEEECCEE | 32.89 | - | |
| 379 | Ubiquitination | LKFRIDGKYIHVHKA EEEEECCEEEEEEEE | 36.97 | - | |
| 380 | Phosphorylation | KFRIDGKYIHVHKAV EEEECCEEEEEEEEH | 11.20 | 29083192 | |
| 385 | Ubiquitination | GKYIHVHKAVLKIRC CEEEEEEEEHHHHHH | 38.82 | - | |
| 464 | Ubiquitination | KLCQHIIKRGITVEN HHHHHHHHCCCCHHH | 43.92 | - | |
| 468 | Phosphorylation | HIIKRGITVENAFSL HHHHCCCCHHHHHHH | 25.29 | 24247654 | |
| 474 | Phosphorylation | ITVENAFSLFSAAVR CCHHHHHHHHHHHHC | 26.54 | 24247654 | |
| 477 | Phosphorylation | ENAFSLFSAAVRYDA HHHHHHHHHHHCCCH | 22.17 | 24247654 | |
| 522 | Ubiquitination | LLKEFIAKASKCGAF HHHHHHHHHHHCCCC | 48.66 | 21906983 | |
| 525 | Ubiquitination | EFIAKASKCGAFKN- HHHHHHHHCCCCCC- | 41.36 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RCBT1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RCBT1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RCBT1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CUL3_HUMAN | CUL3 | physical | 19256485 | |
| A4_HUMAN | APP | physical | 21832049 | |
| ANR40_HUMAN | ANKRD40 | physical | 26186194 | |
| HERC3_HUMAN | HERC3 | physical | 26186194 | |
| ANR40_HUMAN | ANKRD40 | physical | 28514442 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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