ANR40_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ANR40_HUMAN
• UniProt AC: Q6AI12
• Protein Name: Ankyrin repeat domain-containing protein 40
• Gene Name: ANKRD40
• Organism: Homo sapiens (Human).
• Sequence Length: 368
• Protein Sequence: MNALLEQKEQQERLREAAALGDIREVQKLVESGVDVNSQNEVNGWTCLHWACKRNHGQVVSYLLKSGADKEILTTKGEMPVQLTSRREIRKIMGVEEEDDDDDDDDNLPQLKKESELPFVPNYLANPAFPFIYTPTAEDSAQMQNGGPSTPPASPPADGSPPLLPPGEPPLLGTFPRDHTSLALVQNGDVSAPSAILRTPESTKPGPVCQPPVSQSRSLFSSVPSKPPMSLEPQNGTYAGPAPAFQPFFFTGAFPFNMQELVLKVRIQNPSLRENDFIEIELDRQELTYQELLRVCCCELGVNPDQVEKIRKLPNTLLRKDKDVARLQDFQELELVLMISENNFLFRNAASTLTERPCYNRRASKLTY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MNALLEQK -------CCHHHHHH	6.29	22223895
61	Phosphorylation	RNHGQVVSYLLKSGA CCCHHHHHHHHHCCC	15.94	24719451
62	Phosphorylation	NHGQVVSYLLKSGAD CCHHHHHHHHHCCCC	12.39	24719451
65	Ubiquitination	QVVSYLLKSGADKEI HHHHHHHHCCCCCEE	44.22	-
84	Phosphorylation	GEMPVQLTSRREIRK CCCCCEECCHHHHHH	11.78	46164277
91	Ubiquitination	TSRREIRKIMGVEEE CCHHHHHHHHCCCCC	42.58	-
112	Ubiquitination	DDNLPQLKKESELPF CCCHHHHHHHHCCCC	49.61	21906983
160	Phosphorylation	ASPPADGSPPLLPPG CCCCCCCCCCCCCCC	24.72	26074081
180	Phosphorylation	GTFPRDHTSLALVQN CCCCCCCCCEEEEEC	29.71	27251275
181	Phosphorylation	TFPRDHTSLALVQNG CCCCCCCCEEEEECC	14.28	27251275
191	Phosphorylation	LVQNGDVSAPSAILR EEECCCCCCCCEEEC	38.92	29978859
194	Phosphorylation	NGDVSAPSAILRTPE CCCCCCCCEEECCCC	27.88	29978859
199	Phosphorylation	APSAILRTPESTKPG CCCEEECCCCCCCCC	28.15	28985074
202	Phosphorylation	AILRTPESTKPGPVC EEECCCCCCCCCCCC	42.82	29978859
203	Phosphorylation	ILRTPESTKPGPVCQ EECCCCCCCCCCCCC	39.33	29978859
204	Ubiquitination	LRTPESTKPGPVCQP ECCCCCCCCCCCCCC	58.20	-
214	O-linked_Glycosylation	PVCQPPVSQSRSLFS CCCCCCCCCCCCHHH	28.36	29237092
214	Phosphorylation	PVCQPPVSQSRSLFS CCCCCCCCCCCCHHH	28.36	72261199
216	Phosphorylation	CQPPVSQSRSLFSSV CCCCCCCCCCHHHCC	19.14	29978859
289	Phosphorylation	LDRQELTYQELLRVC ECHHHCCHHHHHHHH	16.77	22817900
309	Ubiquitination	VNPDQVEKIRKLPNT CCHHHHHHHHHCCCC	49.29	-
316	Phosphorylation	KIRKLPNTLLRKDKD HHHHCCCCHHHCCCC	25.82	24260401
320	Ubiquitination	LPNTLLRKDKDVARL CCCCHHHCCCCHHHH	69.93	-
364	Phosphorylation	PCYNRRASKLTY--- CCCCCCHHCCCC---	26.79	28857561

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ANR40_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ANR40_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ANR40_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ANR40_HUMAN	ANKRD40	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.