UBP2L_HUMAN - dbPTM
UBP2L_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID UBP2L_HUMAN
UniProt AC Q14157
Protein Name Ubiquitin-associated protein 2-like
Gene Name UBAP2L
Organism Homo sapiens (Human).
Sequence Length 1087
Subcellular Localization
Protein Description Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs)..
Protein Sequence MMTSVGTNRARGNWEQPQNQNQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDGGQTESNEEGKENRDRDRDYSRRRGGPPRRGRGASRGREFRGQENGLDGTKSGGPSGRGTERGRRGRGRGRGGSGRRGGRFSAQGMGTFNPADYAEPANTDDNYGNSSGNTWNNTGHFEPDDGTSAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTPSTMENDSSNLDPSQAPSLAQPLVFSNSKQTAISQPASGNTFSHHSMVSMLGKGFGDVGEAKGGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLKNPSDSAVHSPFTKRQAFTPSSTMMEVFLQEKSPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQKLKQQKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLSDYESTPTTSASSSQAPSSLYTSTASESSSTISSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTSSIPPLNETVSAASLLTTTNQHSSSLGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQQNQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHSGTPAASFNLPSALGSGGPINPATAAAYPPAPFMHILTPHQQPHSQILHHHLQQDGQTGSGQRSQTSSIPQKPQTNKSAYNSYSWGAN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
1Acetylation-------MMTSVGTN
-------CCCCCCCC		31.3022814378
7Phosphorylation-MMTSVGTNRARGNW
-CCCCCCCCCCCCCC		21.26-
11MethylationSVGTNRARGNWEQPQ
CCCCCCCCCCCCCCC		35.4282797045
26 (in isoform 1)Ubiquitination-37.88-
41SulfoxidationEQIRLAQMISDHNDA
HHHHHHHHHHHCCCC		2.3521406390
43PhosphorylationIRLAQMISDHNDADF
HHHHHHHHHCCCCCH		27.7229978859
53AcetylationNDADFEEKVKQLIDI
CCCCHHHHHHHHHHH		47.7526051181
63AcetylationQLIDITGKNQDECVI
HHHHHCCCCCCCEEE		42.6726051181
93PhosphorylationLLEGNPDTHSWEMVG
HHCCCCCCCCEEECC		21.0428450419
95PhosphorylationEGNPDTHSWEMVGKK
CCCCCCCCEEECCEE		27.1628450419
98SulfoxidationPDTHSWEMVGKKKGV
CCCCCEEECCEECCC		3.8130846556
101AcetylationHSWEMVGKKKGVSGQ
CCEEECCEECCCCCC		39.6425953088
101UbiquitinationHSWEMVGKKKGVSGQ
CCEEECCEECCCCCC		39.64-
105UbiquitinationMVGKKKGVSGQKDGG
ECCEECCCCCCCCCC		8.8021890473
106PhosphorylationVGKKKGVSGQKDGGQ
CCEECCCCCCCCCCC		44.1423403867
109UbiquitinationKKGVSGQKDGGQTES
ECCCCCCCCCCCCCC		62.96-
114PhosphorylationGQKDGGQTESNEEGK
CCCCCCCCCCCCCCC		44.6623403867
116PhosphorylationKDGGQTESNEEGKEN
CCCCCCCCCCCCCCC		53.5923401153
121UbiquitinationTESNEEGKENRDRDR
CCCCCCCCCCHHHHH		55.91-
130PhosphorylationNRDRDRDYSRRRGGP
CHHHHHHHHHHCCCC		12.64-
131PhosphorylationRDRDRDYSRRRGGPP
HHHHHHHHHHCCCCC		24.49-
151MethylationASRGREFRGQENGLD
CCCCCCCCCCCCCCC		40.9282954813
168MethylationKSGGPSGRGTERGRR
CCCCCCCCCCCCCCC		53.8830760501
172MethylationPSGRGTERGRRGRGR
CCCCCCCCCCCCCCC		43.7030760507
174MethylationGRGTERGRRGRGRGR
CCCCCCCCCCCCCCC		44.0783364655
184PhosphorylationRGRGRGGSGRRGGRF
CCCCCCCCCCCCCCC		31.76-
187Asymmetric dimethylarginineGRGGSGRRGGRFSAQ
CCCCCCCCCCCCCCC		56.28-
187MethylationGRGGSGRRGGRFSAQ
CCCCCCCCCCCCCCC		56.2824129315
190Asymmetric dimethylarginineGSGRRGGRFSAQGMG
CCCCCCCCCCCCCCC		25.77-
190MethylationGSGRRGGRFSAQGMG
CCCCCCCCCCCCCCC		25.7724129315
204PhosphorylationGTFNPADYAEPANTD
CCCCHHHCCCCCCCC		18.25-
214PhosphorylationPANTDDNYGNSSGNT
CCCCCCCCCCCCCCC		25.36-
225PhosphorylationSGNTWNNTGHFEPDD
CCCCCCCCCCCCCCC		28.90-
239PhosphorylationDGTSAWRTATEEWGT
CCCCCCCHHHHHHCC		27.5128857561
241PhosphorylationTSAWRTATEEWGTED
CCCCCHHHHHHCCCC		33.5528857561
246PhosphorylationTATEEWGTEDWNEDL
HHHHHHCCCCCCCCC		31.6628857561
254PhosphorylationEDWNEDLSETKIFTA
CCCCCCCCCCEEEEE		56.3921815630
256PhosphorylationWNEDLSETKIFTASN
CCCCCCCCEEEEECC		26.5128857561
257UbiquitinationNEDLSETKIFTASNV
CCCCCCCEEEEECCC		31.60-
260O-linked_GlycosylationLSETKIFTASNVSSV
CCCCEEEEECCCCCC		32.4232574038
260PhosphorylationLSETKIFTASNVSSV
CCCCEEEEECCCCCC		32.4228348404
262O-linked_GlycosylationETKIFTASNVSSVPL
CCEEEEECCCCCCCC		34.4132574038
262PhosphorylationETKIFTASNVSSVPL
CCEEEEECCCCCCCC		34.4128348404
265PhosphorylationIFTASNVSSVPLPAE
EEEECCCCCCCCCCC		29.8425159151
266PhosphorylationFTASNVSSVPLPAEN
EEECCCCCCCCCCCC		24.3825159151
277O-linked_GlycosylationPAENVTITAGQRIDL
CCCCCEEECCCEEEE		18.5032574038
290UbiquitinationDLAVLLGKTPSTMEN
EEEHHHCCCCCCCCC		58.18-
290 (in isoform 1)Ubiquitination-58.18-
291PhosphorylationLAVLLGKTPSTMEND
EEHHHCCCCCCCCCC		22.2225159151
293PhosphorylationVLLGKTPSTMENDSS
HHHCCCCCCCCCCCC		45.6925159151
294PhosphorylationLLGKTPSTMENDSSN
HHCCCCCCCCCCCCC		29.7025159151
299PhosphorylationPSTMENDSSNLDPSQ
CCCCCCCCCCCCHHH		32.4827251275
300PhosphorylationSTMENDSSNLDPSQA
CCCCCCCCCCCHHHC		44.2523917254
309PhosphorylationLDPSQAPSLAQPLVF
CCHHHCCCCCCCEEE		39.0828450419
317O-linked_GlycosylationLAQPLVFSNSKQTAI
CCCCEEECCCCCEEE		32.4932574038
317PhosphorylationLAQPLVFSNSKQTAI
CCCCEEECCCCCEEE		32.4928450419
319O-linked_GlycosylationQPLVFSNSKQTAISQ
CCEEECCCCCEEECC		25.5832574038
319PhosphorylationQPLVFSNSKQTAISQ
CCEEECCCCCEEECC		25.5828450419
322O-linked_GlycosylationVFSNSKQTAISQPAS
EECCCCCEEECCCCC		29.6932574038
322PhosphorylationVFSNSKQTAISQPAS
EECCCCCEEECCCCC		29.6927080861
325O-linked_GlycosylationNSKQTAISQPASGNT
CCCCEEECCCCCCCC		27.8732574038
325PhosphorylationNSKQTAISQPASGNT
CCCCEEECCCCCCCC		27.8726356563
329O-linked_GlycosylationTAISQPASGNTFSHH
EEECCCCCCCCCCHH		38.9832574038
329PhosphorylationTAISQPASGNTFSHH
EEECCCCCCCCCCHH		38.9826356563
332O-linked_GlycosylationSQPASGNTFSHHSMV
CCCCCCCCCCHHHHH		30.0032574038
332PhosphorylationSQPASGNTFSHHSMV
CCCCCCCCCCHHHHH		30.0026356563
334O-linked_GlycosylationPASGNTFSHHSMVSM
CCCCCCCCHHHHHHH		20.4632574038
334PhosphorylationPASGNTFSHHSMVSM
CCCCCCCCHHHHHHH		20.4626356563
337PhosphorylationGNTFSHHSMVSMLGK
CCCCCHHHHHHHHCC		18.5626356563
340O-linked_GlycosylationFSHHSMVSMLGKGFG
CCHHHHHHHHCCCCC		10.3132574038
340PhosphorylationFSHHSMVSMLGKGFG
CCHHHHHHHHCCCCC		10.3126356563
344AcetylationSMVSMLGKGFGDVGE
HHHHHHCCCCCCCCC		47.2926051181
344 (in isoform 1)Ubiquitination-47.29-
353AcetylationFGDVGEAKGGSTTGS
CCCCCCCCCCCCCHH		60.5526051181
353UbiquitinationFGDVGEAKGGSTTGS
CCCCCCCCCCCCCHH		60.5521906983
353 (in isoform 1)Ubiquitination-60.55-
353 (in isoform 2)Ubiquitination-60.5521890473
353 (in isoform 3)Ubiquitination-60.5521890473
356PhosphorylationVGEAKGGSTTGSQFL
CCCCCCCCCCHHHHH		31.3125159151
357O-linked_GlycosylationGEAKGGSTTGSQFLE
CCCCCCCCCHHHHHH		38.1532574038
357PhosphorylationGEAKGGSTTGSQFLE
CCCCCCCCCHHHHHH		38.1525159151
358O-linked_GlycosylationEAKGGSTTGSQFLEQ
CCCCCCCCHHHHHHH		36.2132574038
358PhosphorylationEAKGGSTTGSQFLEQ
CCCCCCCCHHHHHHH		36.2123403867
360PhosphorylationKGGSTTGSQFLEQFK
CCCCCCHHHHHHHHH		18.7017525332
368PhosphorylationQFLEQFKTAQALAQL
HHHHHHHHHHHHHHH		25.8720068231
380O-linked_GlycosylationAQLAAQHSQSGSTTT
HHHHHHHCCCCCCCC		17.6032574038
380PhosphorylationAQLAAQHSQSGSTTT
HHHHHHHCCCCCCCC		17.6020068231
382O-linked_GlycosylationLAAQHSQSGSTTTSS
HHHHHCCCCCCCCCC		37.4132574038
382PhosphorylationLAAQHSQSGSTTTSS
HHHHHCCCCCCCCCC		37.4120068231
384PhosphorylationAQHSQSGSTTTSSWD
HHHCCCCCCCCCCCC		28.0329978859
385PhosphorylationQHSQSGSTTTSSWDM
HHCCCCCCCCCCCCC		37.3029978859
386PhosphorylationHSQSGSTTTSSWDMG
HCCCCCCCCCCCCCC		26.7829978859
387PhosphorylationSQSGSTTTSSWDMGS
CCCCCCCCCCCCCCC		22.3529978859
388O-linked_GlycosylationQSGSTTTSSWDMGST
CCCCCCCCCCCCCCC		27.6032574038
388PhosphorylationQSGSTTTSSWDMGST
CCCCCCCCCCCCCCC		27.6029978859
389PhosphorylationSGSTTTSSWDMGSTT
CCCCCCCCCCCCCCC		25.6320068231
394O-linked_GlycosylationTSSWDMGSTTQSPSL
CCCCCCCCCCCCCCE		22.9532574038
394PhosphorylationTSSWDMGSTTQSPSL
CCCCCCCCCCCCCCE		22.9522199227
395O-linked_GlycosylationSSWDMGSTTQSPSLV
CCCCCCCCCCCCCEE		24.1132574038
395PhosphorylationSSWDMGSTTQSPSLV
CCCCCCCCCCCCCEE		24.1122199227
396O-linked_GlycosylationSWDMGSTTQSPSLVQ
CCCCCCCCCCCCEEE		28.8432574038
396PhosphorylationSWDMGSTTQSPSLVQ
CCCCCCCCCCCCEEE		28.8422199227
398PhosphorylationDMGSTTQSPSLVQYD
CCCCCCCCCCEEEEE		17.8629496963
400PhosphorylationGSTTQSPSLVQYDLK
CCCCCCCCEEEEECC		46.5530576142
404PhosphorylationQSPSLVQYDLKNPSD
CCCCEEEEECCCCCC		18.7622199227
410PhosphorylationQYDLKNPSDSAVHSP
EEECCCCCCCCCCCC		54.3020044836
412PhosphorylationDLKNPSDSAVHSPFT
ECCCCCCCCCCCCCC		36.2125159151
416PhosphorylationPSDSAVHSPFTKRQA
CCCCCCCCCCCCCCC		18.3429255136
419PhosphorylationSAVHSPFTKRQAFTP
CCCCCCCCCCCCCCC		28.8022167270
420MethylationAVHSPFTKRQAFTPS
CCCCCCCCCCCCCCC		42.7842359913
420UbiquitinationAVHSPFTKRQAFTPS
CCCCCCCCCCCCCCC		42.7821906983
420 (in isoform 1)Ubiquitination-42.78-
420 (in isoform 2)Ubiquitination-42.7821890473
420 (in isoform 3)Ubiquitination-42.7821890473
425O-linked_GlycosylationFTKRQAFTPSSTMME
CCCCCCCCCCCHHHH		25.8532574038
425PhosphorylationFTKRQAFTPSSTMME
CCCCCCCCCCCHHHH		25.8529255136
427O-linked_GlycosylationKRQAFTPSSTMMEVF
CCCCCCCCCHHHHHH		35.0732574038
427PhosphorylationKRQAFTPSSTMMEVF
CCCCCCCCCHHHHHH		35.0729255136
428O-linked_GlycosylationRQAFTPSSTMMEVFL
CCCCCCCCHHHHHHH		22.8632574038
428PhosphorylationRQAFTPSSTMMEVFL
CCCCCCCCHHHHHHH		22.8629255136
429O-linked_GlycosylationQAFTPSSTMMEVFLQ
CCCCCCCHHHHHHHC		25.5232574038
429PhosphorylationQAFTPSSTMMEVFLQ
CCCCCCCHHHHHHHC		25.5229255136
439O-linked_GlycosylationEVFLQEKSPAVATST
HHHHCCCCCCEEECC		19.8332574038
439PhosphorylationEVFLQEKSPAVATST
HHHHCCCCCCEEECC		19.8329255136
444O-linked_GlycosylationEKSPAVATSTAAPPP
CCCCCEEECCCCCCC		21.7332574038
444PhosphorylationEKSPAVATSTAAPPP
CCCCCEEECCCCCCC		21.7323927012
445O-linked_GlycosylationKSPAVATSTAAPPPP
CCCCEEECCCCCCCC		13.3032574038
445PhosphorylationKSPAVATSTAAPPPP
CCCCEEECCCCCCCC		13.3023927012
446O-linked_GlycosylationSPAVATSTAAPPPPS
CCCEEECCCCCCCCC		23.6032574038
446PhosphorylationSPAVATSTAAPPPPS
CCCEEECCCCCCCCC		23.6023927012
453O-linked_GlycosylationTAAPPPPSSPLPSKS
CCCCCCCCCCCCCCC		50.8132574038
453PhosphorylationTAAPPPPSSPLPSKS
CCCCCCCCCCCCCCC		50.8129255136
454O-linked_GlycosylationAAPPPPSSPLPSKST
CCCCCCCCCCCCCCC		35.9132574038
454PhosphorylationAAPPPPSSPLPSKST
CCCCCCCCCCCCCCC		35.9119664994
458O-linked_GlycosylationPPSSPLPSKSTSAPQ
CCCCCCCCCCCCCCC		47.0932574038
458PhosphorylationPPSSPLPSKSTSAPQ
CCCCCCCCCCCCCCC		47.0929255136
460PhosphorylationSSPLPSKSTSAPQMS
CCCCCCCCCCCCCCC		31.7522167270
461PhosphorylationSPLPSKSTSAPQMSP
CCCCCCCCCCCCCCC		32.4222167270
462PhosphorylationPLPSKSTSAPQMSPG
CCCCCCCCCCCCCCC		45.0722167270
466SulfoxidationKSTSAPQMSPGSSDN
CCCCCCCCCCCCCCC		5.2021406390
467PhosphorylationSTSAPQMSPGSSDNQ
CCCCCCCCCCCCCCC		22.3622167270
470PhosphorylationAPQMSPGSSDNQSSS
CCCCCCCCCCCCCCC		37.5919664994
471PhosphorylationPQMSPGSSDNQSSSP
CCCCCCCCCCCCCCC		46.6322167270
475PhosphorylationPGSSDNQSSSPQPAQ
CCCCCCCCCCCHHHH		38.7522167270
476O-linked_GlycosylationGSSDNQSSSPQPAQQ
CCCCCCCCCCHHHHH		35.9532574038
476PhosphorylationGSSDNQSSSPQPAQQ
CCCCCCCCCCHHHHH		35.9522167270
477O-linked_GlycosylationSSDNQSSSPQPAQQK
CCCCCCCCCHHHHHH		32.5732574038
477PhosphorylationSSDNQSSSPQPAQQK
CCCCCCCCCHHHHHH		32.5719664994
484AcetylationSPQPAQQKLKQQKKK
CCHHHHHHHHHHHHH		45.6426051181
493PhosphorylationKQQKKKASLTSKIPA
HHHHHHHHHCCCCCC		40.8526055452
495PhosphorylationQKKKASLTSKIPALA
HHHHHHHCCCCCCEE		26.0220068231
496PhosphorylationKKKASLTSKIPALAV
HHHHHHCCCCCCEEE		33.6028102081
569PhosphorylationSSNQSQESGYQSGPI
CCCCCCCCCCCCCCC		34.8526074081
571PhosphorylationNQSQESGYQSGPIQS
CCCCCCCCCCCCCCC		14.5826074081
573PhosphorylationSQESGYQSGPIQSTT
CCCCCCCCCCCCCCE		37.7426074081
581PhosphorylationGPIQSTTYTSQNNAQ
CCCCCCEECCCCCCC		12.4122817900
592PhosphorylationNNAQGPLYEQRSTQT
CCCCCCCEECCCCCC		17.1025884760
597PhosphorylationPLYEQRSTQTRRYPS
CCEECCCCCCCCCCC		35.8326074081
599PhosphorylationYEQRSTQTRRYPSSI
EECCCCCCCCCCCCC		19.7326074081
602PhosphorylationRSTQTRRYPSSISSS
CCCCCCCCCCCCCCC		12.2723927012
604PhosphorylationTQTRRYPSSISSSPQ
CCCCCCCCCCCCCCC		31.2226846344
605O-linked_GlycosylationQTRRYPSSISSSPQK
CCCCCCCCCCCCCCH		23.2232574038
605PhosphorylationQTRRYPSSISSSPQK
CCCCCCCCCCCCCCH		23.2222167270
607PhosphorylationRRYPSSISSSPQKDL
CCCCCCCCCCCCHHH		27.0622167270
608PhosphorylationRYPSSISSSPQKDLT
CCCCCCCCCCCHHHH		44.3522167270
609PhosphorylationYPSSISSSPQKDLTQ
CCCCCCCCCCHHHHH		25.2619664994
612AcetylationSISSSPQKDLTQAKN
CCCCCCCHHHHHHHH		59.0826051181
615PhosphorylationSSPQKDLTQAKNGFS
CCCCHHHHHHHHCCC		36.2923927012
618AcetylationQKDLTQAKNGFSSVQ
CHHHHHHHHCCCHHE		48.0326051181
622PhosphorylationTQAKNGFSSVQATQL
HHHHHCCCHHEEEEE		30.8827174698
623PhosphorylationQAKNGFSSVQATQLQ
HHHHCCCHHEEEEEE		18.9129514088
627PhosphorylationGFSSVQATQLQTTQS
CCCHHEEEEEEEECC		16.8428450419
631PhosphorylationVQATQLQTTQSVEGA
HEEEEEEEECCCCCC		35.0828450419
632O-linked_GlycosylationQATQLQTTQSVEGAT
EEEEEEEECCCCCCC		13.0932574038
632PhosphorylationQATQLQTTQSVEGAT
EEEEEEEECCCCCCC		13.0928450419
634PhosphorylationTQLQTTQSVEGATGS
EEEEEECCCCCCCCC		21.7528450419
639PhosphorylationTQSVEGATGSAVKSD
ECCCCCCCCCCCCCC		42.3929514088
641PhosphorylationSVEGATGSAVKSDSP
CCCCCCCCCCCCCCC		26.0728450419
645PhosphorylationATGSAVKSDSPSTSS
CCCCCCCCCCCCCCC		36.4026074081
647PhosphorylationGSAVKSDSPSTSSIP
CCCCCCCCCCCCCCC		28.0426074081
649PhosphorylationAVKSDSPSTSSIPPL
CCCCCCCCCCCCCCC		44.8926074081
650PhosphorylationVKSDSPSTSSIPPLN
CCCCCCCCCCCCCCC		29.8526074081
651PhosphorylationKSDSPSTSSIPPLNE
CCCCCCCCCCCCCCC		30.5226074081
652PhosphorylationSDSPSTSSIPPLNET
CCCCCCCCCCCCCCC		38.9226074081
680O-linked_GlycosylationSSSLGGLSHSEEIPN
CCCCCCCCCCCCCCC		28.3932574038
682O-linked_GlycosylationSLGGLSHSEEIPNTT
CCCCCCCCCCCCCCC		33.2832574038
688O-linked_GlycosylationHSEEIPNTTTTQHSS
CCCCCCCCCCCCCCC		21.8432574038
689O-linked_GlycosylationSEEIPNTTTTQHSST
CCCCCCCCCCCCCCC		34.1932574038
690O-linked_GlycosylationEEIPNTTTTQHSSTL
CCCCCCCCCCCCCCC		23.5532574038
691O-linked_GlycosylationEIPNTTTTQHSSTLS
CCCCCCCCCCCCCCC		23.3832574038
694O-linked_GlycosylationNTTTTQHSSTLSTQQ
CCCCCCCCCCCCCCC		18.3932574038
696O-linked_GlycosylationTTTQHSSTLSTQQNT
CCCCCCCCCCCCCCE		27.9532574038
705O-linked_GlycosylationSTQQNTLSSSTSSGR
CCCCCEECCCCCCCC		21.8732574038
706O-linked_GlycosylationTQQNTLSSSTSSGRT
CCCCEECCCCCCCCC		40.5232574038
709O-linked_GlycosylationNTLSSSTSSGRTSTS
CEECCCCCCCCCCCC		32.5132574038
710O-linked_GlycosylationTLSSSTSSGRTSTST
EECCCCCCCCCCCCE		32.1732574038
713O-linked_GlycosylationSSTSSGRTSTSTLLH
CCCCCCCCCCCEEEE		39.6232574038
713PhosphorylationSSTSSGRTSTSTLLH
CCCCCCCCCCCEEEE		39.62-
714O-linked_GlycosylationSTSSGRTSTSTLLHT
CCCCCCCCCCEEEEE		20.9932574038
714PhosphorylationSTSSGRTSTSTLLHT
CCCCCCCCCCEEEEE		20.9924275569
715O-linked_GlycosylationTSSGRTSTSTLLHTS
CCCCCCCCCEEEEEE		25.7232574038
716O-linked_GlycosylationSSGRTSTSTLLHTSV
CCCCCCCCEEEEEEE		19.4732574038
721O-linked_GlycosylationSTSTLLHTSVESEAN
CCCEEEEEEECCCCC		34.1432574038
722O-linked_GlycosylationTSTLLHTSVESEANL
CCEEEEEEECCCCCC		17.0932574038
722PhosphorylationTSTLLHTSVESEANL
CCEEEEEEECCCCCC		17.0924275569
725O-linked_GlycosylationLLHTSVESEANLHSS
EEEEEECCCCCCCCC		39.5932574038
731O-linked_GlycosylationESEANLHSSSSTFST
CCCCCCCCCCCCEEC		34.7732574038
732O-linked_GlycosylationSEANLHSSSSTFSTT
CCCCCCCCCCCEECC		19.9832574038
732PhosphorylationSEANLHSSSSTFSTT
CCCCCCCCCCCEECC		19.98-
733O-linked_GlycosylationEANLHSSSSTFSTTS
CCCCCCCCCCEECCC		36.0932574038
734O-linked_GlycosylationANLHSSSSTFSTTSS
CCCCCCCCCEECCCC		35.1132574038
735O-linked_GlycosylationNLHSSSSTFSTTSST
CCCCCCCCEECCCCC		24.4532574038
740PhosphorylationSSTFSTTSSTVSAPP
CCCEECCCCCCCCCC		24.89-
770O-linked_GlycosylationGLSLGSNSTVTASTR
CEEECCCCEEEEECC		26.4232574038
776O-linked_GlycosylationNSTVTASTRSSVATT
CCEEEEECCCCCEEC		31.9132574038
778O-linked_GlycosylationTVTASTRSSVATTSG
EEEEECCCCCEECCC		29.2932574038
782O-linked_GlycosylationSTRSSVATTSGKAPP
ECCCCCEECCCCCCC		21.2432574038
782O-linked_GlycosylationSTRSSVATTSGKAPP
ECCCCCEECCCCCCC		21.2420068230
783O-linked_GlycosylationTRSSVATTSGKAPPN
CCCCCEECCCCCCCC		26.2432574038
783O-linked_GlycosylationTRSSVATTSGKAPPN
CCCCCEECCCCCCCC		26.2420068230
803PhosphorylationPPLLPNPYIMAPGLL
CCCCCCCCEECCCHH		15.23-
813PhosphorylationAPGLLHAYPPQVYGY
CCCHHHCCCCCCCCC		12.51-
820PhosphorylationYPPQVYGYDDLQMLQ
CCCCCCCCCHHHHHH		6.65-
829MethylationDLQMLQTRFPLDYYS
HHHHHHHCCCCCEEC		20.4454557657
834PhosphorylationQTRFPLDYYSIPFPT
HHCCCCCEECCCCCC		13.5428176443
835PhosphorylationTRFPLDYYSIPFPTP
HCCCCCEECCCCCCC		10.3728176443
836PhosphorylationRFPLDYYSIPFPTPT
CCCCCEECCCCCCCC		19.9828796482
841O-linked_GlycosylationYYSIPFPTPTTPLTG
EECCCCCCCCCCCCC		33.3832574038
841PhosphorylationYYSIPFPTPTTPLTG
EECCCCCCCCCCCCC		33.3828796482
843PhosphorylationSIPFPTPTTPLTGRD
CCCCCCCCCCCCCCC		43.4528176443
844PhosphorylationIPFPTPTTPLTGRDG
CCCCCCCCCCCCCCC		19.9428176443
844 (in isoform 1)Phosphorylation-19.9418220336
847PhosphorylationPTPTTPLTGRDGSLA
CCCCCCCCCCCCCCC		31.2328176443
852O-linked_GlycosylationPLTGRDGSLASNPYS
CCCCCCCCCCCCCCC		25.6732574038
852PhosphorylationPLTGRDGSLASNPYS
CCCCCCCCCCCCCCC		25.6721945579
855PhosphorylationGRDGSLASNPYSGDL
CCCCCCCCCCCCCCC		43.5621945579
857 (in isoform 4)Ubiquitination-23.3621890473
858PhosphorylationGSLASNPYSGDLTKF
CCCCCCCCCCCCCCC		29.5421945579
859O-linked_GlycosylationSLASNPYSGDLTKFG
CCCCCCCCCCCCCCC		27.3932574038
859PhosphorylationSLASNPYSGDLTKFG
CCCCCCCCCCCCCCC		27.3925159151
863O-linked_GlycosylationNPYSGDLTKFGRGDA
CCCCCCCCCCCCCCC		29.1232574038
863PhosphorylationNPYSGDLTKFGRGDA
CCCCCCCCCCCCCCC		29.1221945579
864AcetylationPYSGDLTKFGRGDAS
CCCCCCCCCCCCCCC		53.7926051181
864UbiquitinationPYSGDLTKFGRGDAS
CCCCCCCCCCCCCCC		53.7921890473
864 (in isoform 1)Ubiquitination-53.7921890473
864 (in isoform 2)Ubiquitination-53.7921890473
864 (in isoform 3)Ubiquitination-53.7921890473
864 (in isoform 5)Ubiquitination-53.79-
871O-linked_GlycosylationKFGRGDASSPAPATT
CCCCCCCCCCCCCCC		41.4132574038
871PhosphorylationKFGRGDASSPAPATT
CCCCCCCCCCCCCCC		41.4126074081
872O-linked_GlycosylationFGRGDASSPAPATTL
CCCCCCCCCCCCCCC		27.1432574038
872PhosphorylationFGRGDASSPAPATTL
CCCCCCCCCCCCCCC		27.1426074081
877O-linked_GlycosylationASSPAPATTLAQPQQ
CCCCCCCCCCCCCCC		22.6832574038
878O-linked_GlycosylationSSPAPATTLAQPQQN
CCCCCCCCCCCCCCC		23.3932574038
887O-linked_GlycosylationAQPQQNQTQTHHTTQ
CCCCCCCCCCCCCCC		42.8832574038
889O-linked_GlycosylationPQQNQTQTHHTTQQT
CCCCCCCCCCCCCCC		21.0032574038
893O-linked_GlycosylationQTQTHHTTQQTFLNP
CCCCCCCCCCCCCCC		17.8332574038
896O-linked_GlycosylationTHHTTQQTFLNPALP
CCCCCCCCCCCCCCC		21.9232574038
907O-linked_GlycosylationPALPPGYSYTSLPYY
CCCCCCCCCCCCCCC		28.0532574038
909O-linked_GlycosylationLPPGYSYTSLPYYTG
CCCCCCCCCCCCCCC		20.1832574038
922O-linked_GlycosylationTGVPGLPSTFQYGPA
CCCCCCCCCCCCCCE		47.0732574038
923O-linked_GlycosylationGVPGLPSTFQYGPAV
CCCCCCCCCCCCCEE		16.9032574038
936O-linked_GlycosylationAVFPVAPTSSKQHGV
EEEEECCCCCCCCCC		35.5832574038
938O-linked_GlycosylationFPVAPTSSKQHGVNV
EEECCCCCCCCCCEE		38.5232574038
946O-linked_GlycosylationKQHGVNVSVNASATP
CCCCCEEEECCCCCC		12.4032574038
950O-linked_GlycosylationVNVSVNASATPFQQP
CEEEECCCCCCCCCC		27.7232574038
951 (in isoform 4)Phosphorylation-19.5125159151
952O-linked_GlycosylationVSVNASATPFQQPSG
EEECCCCCCCCCCCC		23.3432574038
955 (in isoform 4)Phosphorylation-56.3225159151
958 (in isoform 1)Phosphorylation-40.0725159151
958 (in isoform 4)Phosphorylation-40.07-
960PhosphorylationPFQQPSGYGSHGYNT
CCCCCCCCCCCCCCC		21.57-
960 (in isoform 4)Phosphorylation-21.5725159151
962O-linked_GlycosylationQQPSGYGSHGYNTGV
CCCCCCCCCCCCCCE		12.7832574038
962 (in isoform 1)Phosphorylation-12.7825159151
962 (in isoform 4)Methylation-12.7824129315
964 (in isoform 4)Phosphorylation-21.05-
965PhosphorylationSGYGSHGYNTGVSVT
CCCCCCCCCCCEEEE		12.25-
965 (in isoform 1)Phosphorylation-12.25-
967O-linked_GlycosylationYGSHGYNTGVSVTSS
CCCCCCCCCEEEEEC		30.4032574038
967PhosphorylationYGSHGYNTGVSVTSS
CCCCCCCCCEEEEEC		30.40-
967 (in isoform 1)Phosphorylation-30.4025159151
969 (in isoform 1)Methylation-3.8124129315
969 (in isoform 4)Acetylation-3.8119608861
969 (in isoform 4)Ubiquitination-3.8121890473
970O-linked_GlycosylationHGYNTGVSVTSSNTG
CCCCCCEEEEECCCC		22.4832574038
970 (in isoform 1)Ubiquitination-22.48-
971 (in isoform 1)Phosphorylation-5.82-
972O-linked_GlycosylationYNTGVSVTSSNTGVP
CCCCEEEEECCCCCC		20.9432574038
973O-linked_GlycosylationNTGVSVTSSNTGVPD
CCCEEEEECCCCCCC		21.3132574038
973 (in isoform 4)Phosphorylation-21.3120068231
974O-linked_GlycosylationTGVSVTSSNTGVPDI
CCEEEEECCCCCCCC		29.1032574038
976O-linked_GlycosylationVSVTSSNTGVPDISG
EEEEECCCCCCCCCC		41.3132574038
976 (in isoform 1)Acetylation-41.3119608861
976 (in isoform 1)Ubiquitination-41.3121890473
976 (in isoform 4)Phosphorylation-41.3128674419
980 (in isoform 1)Phosphorylation-45.3320068231
982O-linked_GlycosylationNTGVPDISGSVYSKT
CCCCCCCCCEEEECC		32.1832574038
983 (in isoform 1)Phosphorylation-22.8228674419
984O-linked_GlycosylationGVPDISGSVYSKTQQ
CCCCCCCEEEECCHH		15.8732574038
989PhosphorylationSGSVYSKTQQSFEKQ
CCEEEECCHHHHHHC		26.3728102081
992PhosphorylationVYSKTQQSFEKQGFH
EEECCHHHHHHCCCC		26.0929514088
1066PhosphorylationSGQRSQTSSIPQKPQ
CCCCCCCCCCCCCCC		20.7330631047
1067PhosphorylationGQRSQTSSIPQKPQT
CCCCCCCCCCCCCCC		41.4930631047
1071AcetylationQTSSIPQKPQTNKSA
CCCCCCCCCCCCCCC		33.4726051181
1071UbiquitinationQTSSIPQKPQTNKSA
CCCCCCCCCCCCCCC		33.47-
1077PhosphorylationQKPQTNKSAYNSYSW
CCCCCCCCCCCCCCC		37.7525348954
1079PhosphorylationPQTNKSAYNSYSWGA
CCCCCCCCCCCCCCC		16.2522817900
1081PhosphorylationTNKSAYNSYSWGAN-
CCCCCCCCCCCCCC-		14.1025348954
1082PhosphorylationNKSAYNSYSWGAN--
CCCCCCCCCCCCC--		12.5725348954
1083O-linked_GlycosylationKSAYNSYSWGAN---
CCCCCCCCCCCC---		20.8932574038
1083PhosphorylationKSAYNSYSWGAN---
CCCCCCCCCCCC---		20.8925348954
1088 (in isoform 5)Ubiquitination--
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
454SPhosphorylationKinaseCDK1P06493
PSP
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of UBP2L_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of UBP2L_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PRC2A_HUMANPRRC2Aphysical
14667819
YBOX1_HUMANYBX1physical
22939629
XRCC1_HUMANXRCC1physical
22939629
VAPA_HUMANVAPAphysical
22939629
VAMP2_HUMANVAMP2physical
22939629
HNRDL_HUMANHNRNPDLphysical
26344197
ANM1_HUMANPRMT1physical
26381755
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of UBP2L_HUMAN

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Related Literatures of Post-Translational Modification
Acetylation
ReferencePubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-439; SER-453; SER-454; SER-458; SER-460;THR-461; SER-462; SER-467; SER-470; SER-471; SER-475; SER-476;SER-477; SER-608 AND SER-609, AND MASS SPECTROMETRY.
Phosphorylation
ReferencePubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-454; SER-470; SER-477;THR-847 AND SER-859, AND MASS SPECTROMETRY.
"Large-scale proteomics analysis of the human kinome.";
Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.;
Mol. Cell. Proteomics 8:1751-1764(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-453; SER-454; SER-467AND SER-470, AND MASS SPECTROMETRY.
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-439; SER-453; SER-454; SER-458; SER-460;THR-461; SER-462; SER-467; SER-470; SER-471; SER-475; SER-476;SER-477; SER-608 AND SER-609, AND MASS SPECTROMETRY.
"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-416; SER-439; SER-454;SER-467; SER-470; SER-471; SER-477; SER-605; SER-608; SER-609; SER-852AND SER-859, AND MASS SPECTROMETRY.
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle.";
Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.;
Mol. Cell 31:438-448(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-416; SER-454; SER-467;SER-477; SER-604; SER-605 AND SER-609, AND MASS SPECTROMETRY.
"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-609, AND MASSSPECTROMETRY.
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis.";
Wang B., Malik R., Nigg E.A., Korner R.;
Anal. Chem. 80:9526-9533(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-416; SER-609 ANDSER-852, AND MASS SPECTROMETRY.
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage.";
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.;
Science 316:1160-1166(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-360, AND MASSSPECTROMETRY.
"Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry.";
Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.;
Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-416 AND THR-419, ANDMASS SPECTROMETRY.
"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-416 AND THR-844, ANDMASS SPECTROMETRY.
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization.";
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
Nat. Biotechnol. 24:1285-1292(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-453 AND SER-454, ANDMASS SPECTROMETRY.
"Global phosphoproteome of HT-29 human colon adenocarcinoma cells.";
Kim J.-E., Tannenbaum S.R., White F.M.;
J. Proteome Res. 4:1339-1346(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-605 AND SER-609, ANDMASS SPECTROMETRY.
"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-454; SER-467 ANDSER-609, AND MASS SPECTROMETRY.
"Robust phosphoproteomic profiling of tyrosine phosphorylation sitesfrom human T cells using immobilized metal affinity chromatography andtandem mass spectrometry.";
Brill L.M., Salomon A.R., Ficarro S.B., Mukherji M., Stettler-Gill M.,Peters E.C.;
Anal. Chem. 76:2763-2772(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-607, AND MASSSPECTROMETRY.
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-844, AND MASSSPECTROMETRY.
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-419, AND MASSSPECTROMETRY.
"Quantitative phosphoproteome analysis using a dendrimer conjugationchemistry and tandem mass spectrometry.";
Tao W.A., Wollscheid B., O'Brien R., Eng J.K., Li X.-J.,Bodenmiller B., Watts J.D., Hood L., Aebersold R.;
Nat. Methods 2:591-598(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-834, AND MASSSPECTROMETRY.
"Immunoaffinity profiling of tyrosine phosphorylation in cancercells.";
Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H.,Zha X.-M., Polakiewicz R.D., Comb M.J.;
Nat. Biotechnol. 23:94-101(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-835, AND MASSSPECTROMETRY.

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