FA98B_HUMAN - dbPTM
FA98B_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FA98B_HUMAN
UniProt AC Q52LJ0
Protein Name Protein FAM98B
Gene Name FAM98B
Organism Homo sapiens (Human).
Sequence Length 330
Subcellular Localization Nucleus . Cytoplasm .
Protein Description Positively stimulates PRMT1-induced protein arginine dimethylated arginine methylation. [PubMed: 28040436 Promotes colorectal cancer cell malignancy]
Protein Sequence MRGPEPGPQPTMEGDVLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIKSLCNLEESITSAGRDDLESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFLSTELQASQILQNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTTSDIPHMLNQVESKVKDILSKVQKNHVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFGWSDRAKVKTDDIARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAINKVGVSFSTVENELMISYLMFLQILVYFSFMSW
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
25NitrationDTLEALGYKGPLLEE
HHHHHCCCCCCCHHH		17.39-
95PhosphorylationLKEMACPYSVLISGD
HHHHCCCCEEEECCC		15.9921406692
96PhosphorylationKEMACPYSVLISGDI
HHHCCCCEEEECCCH		8.8021406692
100PhosphorylationCPYSVLISGDIKDRL
CCCEEEECCCHHHHH		26.6721406692
104UbiquitinationVLISGDIKDRLKKKE
EEECCCHHHHHHCHH		41.3532015554
142UbiquitinationHKNSQLDKNSEVYQE
CCCCCCCCCHHHHHH		71.602190698
147PhosphorylationLDKNSEVYQEVQAMF
CCCCHHHHHHHHHHH		8.5627642862
162PhosphorylationDTLGIPKSTTSDIPH
HHHCCCCCCCCCHHH		31.4021406692
163PhosphorylationTLGIPKSTTSDIPHM
HHCCCCCCCCCHHHH		36.1221406692
164PhosphorylationLGIPKSTTSDIPHML
HCCCCCCCCCHHHHH		31.3421406692
165PhosphorylationGIPKSTTSDIPHMLN
CCCCCCCCCHHHHHH		33.3621406692
176PhosphorylationHMLNQVESKVKDILS
HHHHHHHHHHHHHHH		43.8421406692
184UbiquitinationKVKDILSKVQKNHVG
HHHHHHHHHHHCCCC		45.2829967540
184AcetylationKVKDILSKVQKNHVG
HHHHHHHHHHHCCCC		45.2818585729
187UbiquitinationDILSKVQKNHVGKPL
HHHHHHHHCCCCCCC		52.5929967540
192UbiquitinationVQKNHVGKPLLKMDL
HHHCCCCCCCHHCCC		31.2521963094
192AcetylationVQKNHVGKPLLKMDL
HHHCCCCCCCHHCCC		31.2526822725
196UbiquitinationHVGKPLLKMDLNSEQ
CCCCCCHHCCCCHHH		37.7429967540
197SulfoxidationVGKPLLKMDLNSEQA
CCCCCHHCCCCHHHH		7.7521406390
216GlutathionylationRINDALSCEYECRRR
HHHHHHHCHHHHHHH		7.2122555962
227AcetylationCRRRMLMKRLDVTVQ
HHHHHHHHHHCEEEH		45.9430588721
235PhosphorylationRLDVTVQSFGWSDRA
HHCEEEHHHCCCCCC		22.76-
239PhosphorylationTVQSFGWSDRAKVKT
EEHHHCCCCCCCCCH		20.00-
243UbiquitinationFGWSDRAKVKTDDIA
HCCCCCCCCCHHHHH		45.2024816145
245UbiquitinationWSDRAKVKTDDIARI
CCCCCCCCHHHHHHH		45.5927667366
246PhosphorylationSDRAKVKTDDIARIY
CCCCCCCHHHHHHHH		41.7229396449
253PhosphorylationTDDIARIYQPKRYAL
HHHHHHHHCCCCCCC		17.1429396449
256UbiquitinationIARIYQPKRYALSPK
HHHHHCCCCCCCCCC		42.3827667366
258PhosphorylationRIYQPKRYALSPKTT
HHHCCCCCCCCCCCH		20.3023186163
261PhosphorylationQPKRYALSPKTTITM
CCCCCCCCCCCHHHH		19.0421815630
263UbiquitinationKRYALSPKTTITMAH
CCCCCCCCCHHHHHH		55.73-
264PhosphorylationRYALSPKTTITMAHL
CCCCCCCCHHHHHHH		27.1528857561
265PhosphorylationYALSPKTTITMAHLL
CCCCCCCHHHHHHHH		22.1528857561
268SulfoxidationSPKTTITMAHLLAAR
CCCCHHHHHHHHHHH		1.6328183972
279PhosphorylationLAAREDLSKIIRTSS
HHHHHHHHHHHHHCC		33.84-
280UbiquitinationAAREDLSKIIRTSSG
HHHHHHHHHHHHCCC		49.8324816145
280AcetylationAAREDLSKIIRTSSG
HHHHHHHHHHHHCCC		49.8325953088
284PhosphorylationDLSKIIRTSSGTSRE
HHHHHHHHCCCCCHH		19.4820068231
285PhosphorylationLSKIIRTSSGTSREK
HHHHHHHCCCCCHHH		19.5420068231
286PhosphorylationSKIIRTSSGTSREKT
HHHHHHCCCCCHHHH		45.5420068231
288PhosphorylationIIRTSSGTSREKTAC
HHHHCCCCCHHHHHH		26.9320068231
289PhosphorylationIRTSSGTSREKTACA
HHHCCCCCHHHHHHE		41.8020068231
292UbiquitinationSSGTSREKTACAINK
CCCCCHHHHHHEEEC		40.0729967540
293PhosphorylationSGTSREKTACAINKV
CCCCHHHHHHEEECC		23.4020068231
299UbiquitinationKTACAINKVGVSFST
HHHHEEECCCCCHHH		33.9624816145
308MethylationGVSFSTVENELMISY
CCCHHHHCHHHHHHH		45.11-
327UbiquitinationQILVYFSFMSW----
HHHHHHHHHCC----		3.0121963094
335MethylationMSW------------
HCC------------		-
356Methylation---------------------------------
---------------------------------		-
384Dimethylation-------------------------------------------------------------
-------------------------------------------------------------		-
384Methylation-------------------------------------------------------------
-------------------------------------------------------------		-
390Methylation-------------------------------------------------------------------
-------------------------------------------------------------------		-
396Methylation-------------------------------------------------------------------------
-------------------------------------------------------------------------		-
396Dimethylation-------------------------------------------------------------------------
-------------------------------------------------------------------------		-
402Methylation-------------------------------------------------------------------------------
-------------------------------------------------------------------------------		-
402Dimethylation-------------------------------------------------------------------------------
-------------------------------------------------------------------------------		-
408Methylation-------------------------------------------------------------------------------------
-------------------------------------------------------------------------------------		-
408Dimethylation-------------------------------------------------------------------------------------
-------------------------------------------------------------------------------------		-
430Phosphorylation-----------------------------------------------------------------------------------------------------------
-----------------------------------------------------------------------------------------------------------		27642862
431Methylation------------------------------------------------------------------------------------------------------------
------------------------------------------------------------------------------------------------------------		-
432Methylation-------------------------------------------------------------------------------------------------------------
-------------------------------------------------------------------------------------------------------------		-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FA98B_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FA98B_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FA98B_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CN166_HUMANC14orf166physical
26344197
AMPB_HUMANRNPEPphysical
26344197
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FA98B_HUMAN

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Related Literatures of Post-Translational Modification

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