RL32_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL32_HUMAN
• UniProt AC: P62910
• Protein Name: 60S ribosomal protein L32
• Gene Name: RPL32
• Organism: Homo sapiens (Human).
• Sequence Length: 135
• Protein Sequence: MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNPNARLRSEENE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Sumoylation	AALRPLVKPKIVKKR CCCCCCCCHHHHCHH	48.56	28112733
9	Ubiquitination	AALRPLVKPKIVKKR CCCCCCCCHHHHCHH	48.56	-
22	Methylation	KRTKKFIRHQSDRYV HHHHHHHHHCCCCEE	25.56	115492073
25	Phosphorylation	KKFIRHQSDRYVKIK HHHHHHCCCCEEEEC	20.24	29514088
27	Methylation	FIRHQSDRYVKIKRN HHHHCCCCEEEECCC	43.31	115492089
37	Sumoylation	KIKRNWRKPRGIDNR EECCCCCCCCCCCHH	30.59	-
50	Succinylation	NRVRRRFKGQILMPN HHHHHHHCCCEECCC	48.36	-
50	Ubiquitination	NRVRRRFKGQILMPN HHHHHHHCCCEECCC	48.36	-
50	Acetylation	NRVRRRFKGQILMPN HHHHHHHCCCEECCC	48.36	25953088
50	Ubiquitination	NRVRRRFKGQILMPN HHHHHHHCCCEECCC	48.36	21890473
50	Succinylation	NRVRRRFKGQILMPN HHHHHHHCCCEECCC	48.36	21890473
50	2-Hydroxyisobutyrylation	NRVRRRFKGQILMPN HHHHHHHCCCEECCC	48.36	-
55	Sulfoxidation	RFKGQILMPNIGYGS HHCCCEECCCCCCCC	2.26	30846556
60	Phosphorylation	ILMPNIGYGSNKKTK EECCCCCCCCCCCCC	17.37	28555341
62	Phosphorylation	MPNIGYGSNKKTKHM CCCCCCCCCCCCCCC	36.67	25159151
62	O-linked_Glycosylation	MPNIGYGSNKKTKHM CCCCCCCCCCCCCCC	36.67	28510447
64	Acetylation	NIGYGSNKKTKHMLP CCCCCCCCCCCCCCC	64.61	25953088
66	Phosphorylation	GYGSNKKTKHMLPSG CCCCCCCCCCCCCCH	28.00	20068231
67	2-Hydroxyisobutyrylation	YGSNKKTKHMLPSGF CCCCCCCCCCCCCHH	35.58	-
67	Acetylation	YGSNKKTKHMLPSGF CCCCCCCCCCCCCHH	35.58	26051181
67	Ubiquitination	YGSNKKTKHMLPSGF CCCCCCCCCCCCCHH	35.58	-
69	Sulfoxidation	SNKKTKHMLPSGFRK CCCCCCCCCCCHHHH	6.66	28183972
72	Phosphorylation	KTKHMLPSGFRKFLV CCCCCCCCHHHHHHH	46.75	20068231
75	Methylation	HMLPSGFRKFLVHNV CCCCCHHHHHHHCCH	32.13	115492081
76	Ubiquitination	MLPSGFRKFLVHNVK CCCCHHHHHHHCCHH	40.57	-
76	2-Hydroxyisobutyrylation	MLPSGFRKFLVHNVK CCCCHHHHHHHCCHH	40.57	-
76	Acetylation	MLPSGFRKFLVHNVK CCCCHHHHHHHCCHH	40.57	25825284
83	Methylation	KFLVHNVKELEVLLM HHHHCCHHHHHHHHH	63.00	30993909
83	Ubiquitination	KFLVHNVKELEVLLM HHHHCCHHHHHHHHH	63.00	-
83	Acetylation	KFLVHNVKELEVLLM HHHHCCHHHHHHHHH	63.00	26051181
91	S-nitrosocysteine	ELEVLLMCNKSYCAE HHHHHHHCCCHHHHH	6.14	-
91	Glutathionylation	ELEVLLMCNKSYCAE HHHHHHHCCCHHHHH	6.14	22555962
91	S-nitrosylation	ELEVLLMCNKSYCAE HHHHHHHCCCHHHHH	6.14	19483679
93	2-Hydroxyisobutyrylation	EVLLMCNKSYCAEIA HHHHHCCCHHHHHHH	37.56	-
93	Acetylation	EVLLMCNKSYCAEIA HHHHHCCCHHHHHHH	37.56	26051181
94	Phosphorylation	VLLMCNKSYCAEIAH HHHHCCCHHHHHHHH	16.08	28152594
95	Phosphorylation	LLMCNKSYCAEIAHN HHHCCCHHHHHHHHH	9.40	28152594
95	Nitration	LLMCNKSYCAEIAHN HHHCCCHHHHHHHHH	9.40	-
96	Glutathionylation	LMCNKSYCAEIAHNV HHCCCHHHHHHHHHC	3.37	22555962
96	S-nitrosylation	LMCNKSYCAEIAHNV HHCCCHHHHHHHHHC	3.37	2212679
96	S-palmitoylation	LMCNKSYCAEIAHNV HHCCCHHHHHHHHHC	3.37	26865113
104	Phosphorylation	AEIAHNVSSKNRKAI HHHHHHCCCCCHHHH	40.69	28985074
105	Phosphorylation	EIAHNVSSKNRKAIV HHHHHCCCCCHHHHH	29.66	23312004
106	2-Hydroxyisobutyrylation	IAHNVSSKNRKAIVE HHHHCCCCCHHHHHH	53.95	-
106	Ubiquitination	IAHNVSSKNRKAIVE HHHHCCCCCHHHHHH	53.95	-
106	Acetylation	IAHNVSSKNRKAIVE HHHHCCCCCHHHHHH	53.95	26051181
114	Methylation	NRKAIVERAAQLAIR CHHHHHHHHHHHHHH	25.08	115492065
128	Methylation	RVTNPNARLRSEENE HHCCCCHHHCCCCCC	36.96	115492097
131	Phosphorylation	NPNARLRSEENE--- CCCHHHCCCCCC---	54.58	29743597

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL32_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL32_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL32_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RL5_HUMAN	RPL5	physical	22939629
RL7_HUMAN	RPL7	physical	22939629
RL8_HUMAN	RPL8	physical	22939629
RL9_HUMAN	RPL9	physical	22939629
RS23_HUMAN	RPS23	physical	22939629
RS26_HUMAN	RPS26	physical	22939629
RS2_HUMAN	RPS2	physical	22939629
RS3_HUMAN	RPS3	physical	22939629
RS4X_HUMAN	RPS4X	physical	22939629
RS6_HUMAN	RPS6	physical	22939629
RL7A_HUMAN	RPL7A	physical	22939629
RS8_HUMAN	RPS8	physical	22939629
RL4_HUMAN	RPL4	physical	22939629
RSSA_HUMAN	RPSA	physical	22939629
RS20_HUMAN	RPS20	physical	22939629
RS15A_HUMAN	RPS15A	physical	22939629
RS16_HUMAN	RPS16	physical	22939629
RS3A_HUMAN	RPS3A	physical	22939629
RL3_HUMAN	RPL3	physical	22939629
RL17_HUMAN	RPL17	physical	26344197
RL23A_HUMAN	RPL23A	physical	26344197
RL27A_HUMAN	RPL27A	physical	26344197
RL35A_HUMAN	RPL35A	physical	26344197
RL37A_HUMAN	RPL37A	physical	26344197
RL39_HUMAN	RPL39	physical	26344197
RL4_HUMAN	RPL4	physical	26344197
RL5_HUMAN	RPL5	physical	26344197
RL7_HUMAN	RPL7	physical	26344197
RL7A_HUMAN	RPL7A	physical	26344197
RL9_HUMAN	RPL9	physical	26344197
RS13_HUMAN	RPS13	physical	26344197
RS16_HUMAN	RPS16	physical	26344197
RS4X_HUMAN	RPS4X	physical	26344197
RS6_HUMAN	RPS6	physical	26344197
RL40_HUMAN	UBA52	physical	26344197
THOC4_HUMAN	ALYREF	physical	27173435
UBIM_HUMAN	FAU	physical	27173435
LSM4_HUMAN	LSM4	physical	27173435
LSM8_HUMAN	LSM8	physical	27173435
SART3_HUMAN	SART3	physical	27173435

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.