dbPTM

YTDC2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YTDC2_HUMAN
UniProt AC	Q9H6S0
Protein Name	3'-5' RNA helicase YTHDC2 {ECO:0000305}
Gene Name	YTHDC2 {ECO:0000303\|PubMed:29033321, ECO:0000312\|HGNC:HGNC:24721}
Organism	Homo sapiens (Human).
Sequence Length	1430
Subcellular Localization	Cytoplasm .
Protein Description	3'-5' RNA helicase that plays a key role in the male and female germline by promoting transition from mitotic to meiotic divisions in stem cells. [PubMed: 26318451]
Protein Sequence	MSRPSSVSPRQPAPGGGGGGGPSPCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGDQREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQIPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQEEKQQTTLTEWYSAQENSFKPESQRQRTVLNVTDEYDLLDDGGDAVFSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDIDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSATLEFGNLDESSLVQTNGSDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRAPSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSSADTEFSDECTTAERVLMKSPSPALHPPQKYKDRGILHPKRGTEDRSDQSSLKSTDSSSYPSPCASPSPPSSGKGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQELEPLVGEQLLQLWERLPLGEKNTTD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSRPSSVSP ------CCCCCCCCC	65.29	30206219
3	Methylation	-----MSRPSSVSPR -----CCCCCCCCCC	47.15	115388733
5	Phosphorylation	---MSRPSSVSPRQP ---CCCCCCCCCCCC	42.11	30206219
6	Phosphorylation	--MSRPSSVSPRQPA --CCCCCCCCCCCCC	29.33	20873877
8	Phosphorylation	MSRPSSVSPRQPAPG CCCCCCCCCCCCCCC	19.13	25159151
10	Dimethylation	RPSSVSPRQPAPGGG CCCCCCCCCCCCCCC	47.83	-
10	Methylation	RPSSVSPRQPAPGGG CCCCCCCCCCCCCCC	47.83	30763533
18	Ubiquitination	QPAPGGGGGGGPSPC CCCCCCCCCCCCCCC	34.54	22817900
23	Phosphorylation	GGGGGGPSPCGPGGG CCCCCCCCCCCCCCC	35.78	25159151
32	Methylation	CGPGGGGRAKGLKDI CCCCCCCCCCCCCCC	36.08	115388741
34	Methylation	PGGGGRAKGLKDIRI CCCCCCCCCCCCCCC	64.51	116253789
36	Ubiquitination	GGGRAKGLKDIRIDE CCCCCCCCCCCCCCH	4.43	29967540
42	Ubiquitination	GLKDIRIDEEVKIAV CCCCCCCCHHHHHHH	35.83	29967540
60	Ubiquitination	LERFRYGDQREMEFP HHHHCCCCCCCCCCC	35.11	22817900
72	Phosphorylation	EFPSSLTSTERAFIH CCCCCCCHHHHHHHH	33.30	28555341
82	Phosphorylation	RAFIHRLSQSLGLVS HHHHHHHHHHHCCCC	20.06	28555341
84	Phosphorylation	FIHRLSQSLGLVSKS HHHHHHHHHCCCCCC	22.49	28555341
90	Ubiquitination	QSLGLVSKSKGKGAN HHHCCCCCCCCCCCC	49.02	29967540
92	Ubiquitination	LGLVSKSKGKGANRY HCCCCCCCCCCCCCE	69.27	29967540
106	Ubiquitination	YLTVKKKDGSETAHA EEEEEECCCCHHEEE	74.79	29967540
116	Phosphorylation	ETAHAMMTCNLTHNT HHEEEEEEECCCCCH	5.78	-
120	Phosphorylation	AMMTCNLTHNTKHAV EEEEECCCCCHHHHH	10.09	-
123	Phosphorylation	TCNLTHNTKHAVRSL EECCCCCHHHHHHHH	19.32	-
123	Ubiquitination	TCNLTHNTKHAVRSL EECCCCCHHHHHHHH	19.32	29967540
142	Phosphorylation	PVTNKERTELLPKTE CCCCHHHHCCCCCCC	31.88	24719451
156	Ubiquitination	ERGNVFAVEAENREM CCCCEEEEEECCHHH	4.94	29967540
164	Phosphorylation	EAENREMSKTSGRLN EECCHHHHCCCCCCC	28.20	24719451
180	Ubiquitination	GIPQIPVKRGESEFD CCCCCCCCCCCCHHH	49.70	21906983
184	Phosphorylation	IPVKRGESEFDSFRQ CCCCCCCCHHHHHHH	46.52	20873877
188	Phosphorylation	RGESEFDSFRQSLPV CCCCHHHHHHHHCCC	27.87	20873877
198	Ubiquitination	QSLPVFEKQEEIVKI HHCCCCCCHHHHHHH	52.09	29967540
204	Ubiquitination	EKQEEIVKIIKENKV CCHHHHHHHHHHCCE	44.36	29967540
222	Ubiquitination	VGETGSGKTTQIPQF EECCCCCCCCCCCHH	50.53	22817900
230	Ubiquitination	TTQIPQFLLDDCFKN CCCCCHHHHHHHHHC	4.28	29967540
236	Ubiquitination	FLLDDCFKNGIPCRI HHHHHHHHCCCCEEE	61.67	-
244	Ubiquitination	NGIPCRIFCTQPRRL CCCCEEEEECCHHHH	1.58	29967540
261	Ubiquitination	IAVAERVAAERRERI HHHHHHHHHHHHHHH	15.15	29967540
271	Phosphorylation	RRERIGQTIGYQIRL HHHHHCCHHCHHHCC	15.91	24719451
274	Phosphorylation	RIGQTIGYQIRLESR HHCCHHCHHHCCCCC	9.27	24719451
280	Phosphorylation	GYQIRLESRVSPKTL CHHHCCCCCCCCHHH	42.44	24719451
285	Ubiquitination	LESRVSPKTLLTFCT CCCCCCCHHHHHHHC	44.28	-
293	Ubiquitination	TLLTFCTNGVLLRTL HHHHHHCCCHHHHHH	39.49	29967540
294	Ubiquitination	LLTFCTNGVLLRTLM HHHHHCCCHHHHHHH	8.03	29967540
333	Phosphorylation	DFLLTKLRDLLQKHP HHHHHHHHHHHHHCC	33.80	15302935
347	Phosphorylation	PTLKLILSSAALDVN CCHHHHHHHHCCCHH	15.78	20068231
375	Ubiquitination	IQGRPFEVKEMFLED ECCCEEEHHHHHHHH	6.96	29967540
390	Phosphorylation	ILRTTGYTNKEMLKY HHHHHCCCCHHHHHH	40.95	26714015
392	Ubiquitination	RTTGYTNKEMLKYKK HHHCCCCHHHHHHHH	36.38	29967540
392	Acetylation	RTTGYTNKEMLKYKK HHHCCCCHHHHHHHH	36.38	26051181
399	Acetylation	KEMLKYKKEKQQEEK HHHHHHHHHHHHHHH	68.03	20167786
406	Acetylation	KEKQQEEKQQTTLTE HHHHHHHHHHHHHHH	47.13	20167786
406	Ubiquitination	KEKQQEEKQQTTLTE HHHHHHHHHHHHHHH	47.13	29967540
409	Phosphorylation	QQEEKQQTTLTEWYS HHHHHHHHHHHHHHH	22.68	22210691
410	Phosphorylation	QEEKQQTTLTEWYSA HHHHHHHHHHHHHHH	27.61	29978859
412	Phosphorylation	EKQQTTLTEWYSAQE HHHHHHHHHHHHHHC	23.52	29978859
415	Phosphorylation	QTTLTEWYSAQENSF HHHHHHHHHHHCCCC	6.46	29978859
416	Phosphorylation	TTLTEWYSAQENSFK HHHHHHHHHHCCCCC	25.25	29978859
421	Phosphorylation	WYSAQENSFKPESQR HHHHHCCCCCCHHHH	33.62	29978859
423	Ubiquitination	SAQENSFKPESQRQR HHHCCCCCCHHHHCC	47.93	29967540
431	Phosphorylation	PESQRQRTVLNVTDE CHHHHCCEEEEECCC	22.47	-
431	Ubiquitination	PESQRQRTVLNVTDE CHHHHCCEEEEECCC	22.47	29967540
439	Phosphorylation	VLNVTDEYDLLDDGG EEEECCCCHHCCCCC	18.07	-
441	Ubiquitination	NVTDEYDLLDDGGDA EECCCCHHCCCCCCC	5.75	27667366
456	Ubiquitination	VFSQLTEKDVNCLEP HHHHCCHHCCCCCHH	62.84	29967540
504	Phosphorylation	VSVDYRHSETSATAL CCCCCCCCCCHHHHH	33.30	29457462
506	Phosphorylation	VDYRHSETSATALMV CCCCCCCCHHHHHHH	27.03	30177828
507	Phosphorylation	DYRHSETSATALMVA CCCCCCCHHHHHHHH	21.41	30177828
509	Phosphorylation	RHSETSATALMVAAG CCCCCHHHHHHHHCC	21.79	30177828
510	Phosphorylation	HSETSATALMVAAGR CCCCHHHHHHHHCCC	8.06	15302935
513	Ubiquitination	TSATALMVAAGRGFA CHHHHHHHHCCCCHH	3.25	29967540
521	Phosphorylation	AAGRGFASQVEQLIS HCCCCHHHHHHHHHH	32.28	29052541
535	Phosphorylation	SMGANVHSKASNGWM HCCCCCCCCCCCCCC	26.15	29457462
593	Ubiquitination	AEDRELLKAYHHSFD HHHHHHHHHHHHCCC	60.57	29967540
609	Ubiquitination	EKVDLDLIMHLLYNI CCCCHHHHHHHHHHH	1.31	27667366
647	Ubiquitination	DRILFDDKRFADSTH CCEECCCHHHCCCCC	51.78	-
675	Ubiquitination	SDQKKVLKNPPAGVR CCCHHHHCCCCCCHH	71.09	29967540
697	Ubiquitination	IAETSITVNDVVFVI CCCCEEEECCEEEEE	5.69	29967540
715	Ubiquitination	KVKEKSFDALNFVTM CCCCCCCHHHHHHHH	58.18	29967540
732	Ubiquitination	MVWISKASAIQRKGR HHHHHHHHHHHHCCC	29.64	24816145
736	Methylation	SKASAIQRKGRAGRC HHHHHHHHCCCCCCC	36.96	18583727
739	Methylation	SAIQRKGRAGRCRPG HHHHHCCCCCCCCCC	36.58	18583735
747	Ubiquitination	AGRCRPGICFRLFSR CCCCCCCHHHHHHHH	1.91	27667366
821	Phosphorylation	KTIDAMDTWEDLTEL HHHCCCCCHHHHHHH	20.05	29759185
835	Ubiquitination	LGYHLADLPVEPHLG HHHHHHCCCCCCCHH	4.21	29967540
839	Ubiquitination	LADLPVEPHLGKMVL HHCCCCCCCHHHHHH	28.39	21890473
853	Ubiquitination	LCAVVLKCLDPILTI HHHHHHHHHHHHHHH	4.57	29967540
874	Phosphorylation	RDPFVLPTQASQKRA CCCCCCCCHHHHHHH	32.38	20873877
877	Phosphorylation	FVLPTQASQKRAAML CCCCCHHHHHHHHHH	26.81	20873877
900	Ubiquitination	AFSDHMALLRAFQAW CCHHHHHHHHHHHHH	2.30	24816145
909	Ubiquitination	RAFQAWQKARSDGWE HHHHHHHHHHCCCHH	34.76	27667366
909	Acetylation	RAFQAWQKARSDGWE HHHHHHHHHHCCCHH	34.76	26051181
920	Ubiquitination	DGWERAFCEKNFLSQ CCHHHHHHHHHHHHH	7.70	29967540
921	Phosphorylation	GWERAFCEKNFLSQA CHHHHHHHHHHHHHH	44.58	32142685
947	Phosphorylation	LLGQLRASGFVRARG HHHHHHHCCCCCCCC	26.74	-
967	Phosphorylation	DVNTNSENWAVVKAA CCCCCCCCHHHHHHH	31.65	33259812
994	Phosphorylation	DRENLVLTGPKEKKV CCHHCEEECCCCCCE	43.91	21406692
997	Ubiquitination	NLVLTGPKEKKVRFH HCEEECCCCCCEECC	81.27	29967540
1007	Phosphorylation	KVRFHPASVLSQPQY CEECCCCHHCCCCCC	28.21	20873877
1007	Ubiquitination	KVRFHPASVLSQPQY CEECCCCHHCCCCCC	28.21	21890473
1010	Phosphorylation	FHPASVLSQPQYKKI CCCCHHCCCCCCCCC	37.34	20873877
1015	Ubiquitination	VLSQPQYKKIPPANG HCCCCCCCCCCCCCC	38.69	29967540
1016	Ubiquitination	LSQPQYKKIPPANGQ CCCCCCCCCCCCCCC	56.35	-
1038	Ubiquitination	PTDWLIYDEMTRAHR CCCEEECCCCCHHHH	32.00	24816145
1056	Phosphorylation	IRCCSAVTPVTILVF CCCCCCCCCEEEEEE	16.26	-
1058	Ubiquitination	CCSAVTPVTILVFCG CCCCCCCEEEEEEEC	3.67	29967540
1059	Phosphorylation	CSAVTPVTILVFCGP CCCCCCEEEEEEECH	15.14	32142685
1071	Phosphorylation	CGPARLASNALQEPS ECHHHHHHCCCCCCC	27.51	26074081
1078	Phosphorylation	SNALQEPSSFRVDGI HCCCCCCCCCCCCCC	41.16	28450419
1079	Phosphorylation	NALQEPSSFRVDGIP CCCCCCCCCCCCCCC	27.99	28450419
1089	Phosphorylation	VDGIPNDSSDSEMED CCCCCCCCCCCHHCC	42.56	29255136
1090	Phosphorylation	DGIPNDSSDSEMEDK CCCCCCCCCCHHCCH	48.28	29255136
1092	Phosphorylation	IPNDSSDSEMEDKTT CCCCCCCCHHCCHHH	40.57	29255136
1098	Phosphorylation	DSEMEDKTTANLAAL CCHHCCHHHHHHHHH	43.38	23927012
1099	Phosphorylation	SEMEDKTTANLAALK CHHCCHHHHHHHHHC	21.20	23927012
1105	Phosphorylation	TTANLAALKLDEWLH HHHHHHHHCHHHHHH	4.75	33259812
1126	Ubiquitination	AASLLLQLRQKWHSL HHHHHHHHHHHHHHH	6.72	33845483
1143	Ubiquitination	RRMRAPSKPWSQVDE HHHCCCCCCHHHCCH	49.82	-
1145	Ubiquitination	MRAPSKPWSQVDEAT HCCCCCCHHHCCHHH	12.72	21890473
1173	Phosphorylation	SAGLQQPSGIGQRPR HCCCCCCCCCCCCCC	38.41	22210691
1183	Phosphorylation	GQRPRPMSSEELPLA CCCCCCCCCCCCCCC	36.96	30108239
1184	Phosphorylation	QRPRPMSSEELPLAS CCCCCCCCCCCCCCC	28.92	25106551
1191	Phosphorylation	SEELPLASSWRSNNS CCCCCCCCHHCCCCC	37.81	23312004
1192	Phosphorylation	EELPLASSWRSNNSR CCCCCCCHHCCCCCC	22.39	23312004
1195	Phosphorylation	PLASSWRSNNSRKSS CCCCHHCCCCCCCCC	33.82	28450419
1198	Phosphorylation	SSWRSNNSRKSSADT CHHCCCCCCCCCCCC	45.39	30576142
1200	Ubiquitination	WRSNNSRKSSADTEF HCCCCCCCCCCCCCC	48.89	24816145
1201	Phosphorylation	RSNNSRKSSADTEFS CCCCCCCCCCCCCCC	29.64	23401153
1202	Phosphorylation	SNNSRKSSADTEFSD CCCCCCCCCCCCCCH	32.95	29255136
1205	Phosphorylation	SRKSSADTEFSDECT CCCCCCCCCCCHHCC	38.35	29255136
1208	Phosphorylation	SSADTEFSDECTTAE CCCCCCCCHHCCHHH	26.68	23927012
1211	Glutathionylation	DTEFSDECTTAERVL CCCCCHHCCHHHHHH	5.00	22555962
1212	Phosphorylation	TEFSDECTTAERVLM CCCCHHCCHHHHHHH	27.30	23663014
1213	Phosphorylation	EFSDECTTAERVLMK CCCHHCCHHHHHHHC	37.87	23663014
1220	Methylation	TAERVLMKSPSPALH HHHHHHHCCCCCCCC	55.86	115978437
1220	Ubiquitination	TAERVLMKSPSPALH HHHHHHHCCCCCCCC	55.86	29967540
1221	Phosphorylation	AERVLMKSPSPALHP HHHHHHCCCCCCCCC	19.35	29255136
1223	Phosphorylation	RVLMKSPSPALHPPQ HHHHCCCCCCCCCCC	29.87	30266825
1231	Methylation	PALHPPQKYKDRGIL CCCCCCCCCCCCCCC	61.10	115978445
1255	Phosphorylation	SDQSSLKSTDSSSYP CCHHHCCCCCCCCCC	42.62	23090842
1256	Phosphorylation	DQSSLKSTDSSSYPS CHHHCCCCCCCCCCC	38.01	23090842
1258	Phosphorylation	SSLKSTDSSSYPSPC HHCCCCCCCCCCCCC	22.67	23090842
1259	Phosphorylation	SLKSTDSSSYPSPCA HCCCCCCCCCCCCCC	36.38	23090842
1260	Phosphorylation	LKSTDSSSYPSPCAS CCCCCCCCCCCCCCC	45.04	25159151
1261	Phosphorylation	KSTDSSSYPSPCASP CCCCCCCCCCCCCCC	15.07	23090842
1263	Phosphorylation	TDSSSYPSPCASPSP CCCCCCCCCCCCCCC	25.12	25159151
1264	Ubiquitination	DSSSYPSPCASPSPP CCCCCCCCCCCCCCC	17.12	33845483
1267	Phosphorylation	SYPSPCASPSPPSSG CCCCCCCCCCCCCCC	32.40	25159151
1269	Phosphorylation	PSPCASPSPPSSGKG CCCCCCCCCCCCCCC	47.12	25159151
1272	Phosphorylation	CASPSPPSSGKGSKS CCCCCCCCCCCCCCC	55.92	22115753
1273	Phosphorylation	ASPSPPSSGKGSKSP CCCCCCCCCCCCCCC	50.74	22617229
1275	Acetylation	PSPPSSGKGSKSPSP CCCCCCCCCCCCCCC	63.06	26051181
1277	Phosphorylation	PPSSGKGSKSPSPRP CCCCCCCCCCCCCCC	33.18	28176443
1279	Phosphorylation	SSGKGSKSPSPRPNM CCCCCCCCCCCCCCC	32.10	30278072
1281	Phosphorylation	GKGSKSPSPRPNMPV CCCCCCCCCCCCCCC	40.40	30278072
1290	Phosphorylation	RPNMPVRYFIMKSSN CCCCCCEEEEEECCC	9.55	21406692
1295	Phosphorylation	VRYFIMKSSNLRNLE CEEEEEECCCCCCCC	13.69	21406692
1296	Phosphorylation	RYFIMKSSNLRNLEI EEEEEECCCCCCCCH	34.07	21406692
1307	Ubiquitination	NLEISQQKGIWSTTP CCCHHHCCCCCCCCC	44.73	22817900
1312	Phosphorylation	QQKGIWSTTPSNERK HCCCCCCCCCCCHHH	27.94	26270265
1313	Phosphorylation	QKGIWSTTPSNERKL CCCCCCCCCCCHHHH	21.14	25159151
1315	Phosphorylation	GIWSTTPSNERKLNR CCCCCCCCCHHHHHH	49.59	26270265
1356	Ubiquitination	SSEIGREKSQDWGSA CCCCCCHHCCCCCCC	52.64	-
1357	Phosphorylation	SEIGREKSQDWGSAG CCCCCHHCCCCCCCC	28.72	20873877
1362	Phosphorylation	EKSQDWGSAGLGGVF HHCCCCCCCCCCCEE	18.21	20873877
1426	Ubiquitination	ERLPLGEKNTTD--- HHCCCCCCCCCC---	58.77	21906983
1428	Phosphorylation	LPLGEKNTTD----- CCCCCCCCCC-----	43.33	23312004
1429	Phosphorylation	PLGEKNTTD------ CCCCCCCCC------	49.45	23312004

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YTDC2_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YTDC2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YTDC2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YTDC2_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YTDC2_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1089 AND SER-1273, ANDMASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1263; SER-1267 ANDSER-1269, AND MASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1279 AND SER-1281, ANDMASS SPECTROMETRY.	18669648 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1089 AND MASSSPECTROMETRY.	17081983 [Abstract]