dbPTM

CUL5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CUL5_HUMAN
UniProt AC	Q93034
Protein Name	Cullin-5
Gene Name	CUL5
Organism	Homo sapiens (Human).
Sequence Length	780
Subcellular Localization
Protein Description	Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor..
Protein Sequence	MATSNLLKNKGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLMGKQGSNKKSNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Ubiquitination	MATSNLLKNKGSLQF CCCCHHHCCCCCCCC	60.83	33845483
10	Ubiquitination	TSNLLKNKGSLQFED CCHHHCCCCCCCCCC	48.57	29967540
12	Phosphorylation	NLLKNKGSLQFEDKW HHHCCCCCCCCCCCH	22.17	22985185
34	Phosphorylation	LKLLRQESVTKQQWF HHHHHCCCCCHHHHH	27.09	29507054
36	Phosphorylation	LLRQESVTKQQWFDL HHHCCCCCHHHHHHH	32.20	28450419
74	Ubiquitination	EDILEFIKQAQARVL HHHHHHHHHHHHHHH	44.92	29967540
82	Phosphorylation	QAQARVLSHQDDTAL HHHHHHHCCCCCHHH	19.08	29449344
87	Phosphorylation	VLSHQDDTALLKAYI HHCCCCCHHHHHHHH	27.74	29449344
123	Ubiquitination	ITLMGKQGSNKKSNV EEEECCCCCCCCCCH	36.35	21890473
124	Phosphorylation	TLMGKQGSNKKSNVE EEECCCCCCCCCCHH	42.87	-
128	Phosphorylation	KQGSNKKSNVEDSIV CCCCCCCCCHHHHHH	47.95	-
183	Phosphorylation	LVIGVRESYVNLCSN EEEEEEHHHHHCCCC	24.66	29083192
184	Phosphorylation	VIGVRESYVNLCSNP EEEEEHHHHHCCCCH	6.65	29083192
189	Phosphorylation	ESYVNLCSNPEDKLQ HHHHHCCCCHHHHHH	59.59	29083192
194	Ubiquitination	LCSNPEDKLQIYRDN CCCCHHHHHHHHHHH	40.40	29967540
210	Phosphorylation	EKAYLDSTERFYRTQ HHHHHHCCCHHHHCC	30.74	18669648
231	Ubiquitination	QNGVQNYMKYADAKL HCCHHHHHHHHHHHC	3.34	24816145
232	Ubiquitination	NGVQNYMKYADAKLK CCHHHHHHHHHHHCH	27.25	32015554
237	Ubiquitination	YMKYADAKLKEEEKR HHHHHHHHCHHHHHH	61.72	29967540
268	Ubiquitination	LMECCVNALVTSFKE HHHHHHHHHHHHHHH	5.30	21890473
286	Acetylation	AECQGMIKRNETEKL HHHHHHHHCCCHHHH	40.03	30587963
325	Ubiquitination	IISAGLADMVAAAET HHHHHHHHHHHHHHH	36.81	21890473
346	Phosphorylation	KYVEQLLTLFNRFSK HHHHHHHHHHHHHHH	37.58	20068231
356	Ubiquitination	NRFSKLVKEAFQDDP HHHHHHHHHHHCCCC	54.48	29967540
373	Phosphorylation	LTARDKAYKAVVNDA CCHHHHHHHHHHCCC	12.76	16497976
384	Ubiquitination	VNDATIFKLELPLKQ HCCCEEEEEEECCCC	36.88	21890473
397	Ubiquitination	KQKGVGLKTQPESKC CCCCCCCCCCCHHHC	38.90	29967540
433	Ubiquitination	TSEEIEAKLKEVLLV CHHHHHHHHHHHHHH	47.50	24816145
447	Acetylation	VLKYVQNKDVFMRYH HHHHHCCCCHHHHHH	37.87	24468231
455	Acetylation	DVFMRYHKAHLTRRL CHHHHHHHHHHHHHH	28.68	24468241
463	Ubiquitination	AHLTRRLILDISADS HHHHHHHHEECCCCC	2.85	23000965
466	Ubiquitination	TRRLILDISADSEIE HHHHHEECCCCCHHH	3.07	23000965
467	Ubiquitination	RRLILDISADSEIEE HHHHEECCCCCHHHH	26.20	23000965
470	Ubiquitination	ILDISADSEIEENMV HEECCCCCHHHHHHH	39.94	21890473
492	Ubiquitination	MPADYVNKLARMFQD CCHHHHHHHHHHHHH	33.22	24816145
529	Ubiquitination	PADSVNIKILNAGAW CCCCCCEEEECCCCC	35.62	21890473
537	Phosphorylation	ILNAGAWSRSSEKVF EECCCCCCCCCCCEE	23.04	29514088
539	Phosphorylation	NAGAWSRSSEKVFVS CCCCCCCCCCCEEEE	37.02	29514088
540	Phosphorylation	AGAWSRSSEKVFVSL CCCCCCCCCCEEEEC	40.08	29514088
620	Ubiquitination	KISFENLKLATELPD HCCHHHHHHHHCCCC	47.89	-
631	Methylation	ELPDAELRRTLWSLV CCCCHHHHHHHHHHH	22.50	-
633	Phosphorylation	PDAELRRTLWSLVAF CCHHHHHHHHHHHHC	26.58	24670416
656	Phosphorylation	LYEPQVNSPKDFTEG EECCCCCCCCCCCCC	34.17	-
665	Ubiquitination	KDFTEGTLFSVNQEF CCCCCCCCEEECHHH	4.41	23000965
668	Ubiquitination	TEGTLFSVNQEFSLI CCCCCEEECHHHHHH	7.21	23000965
669	Ubiquitination	EGTLFSVNQEFSLIK CCCCEEECHHHHHHH	34.17	23000965
673	Phosphorylation	FSVNQEFSLIKNAKV EEECHHHHHHHCCCC	28.56	24719451
695	Phosphorylation	LIGRLQLTTERMREE EEEEEECCHHHHHHH	17.41	21722762
696	Phosphorylation	IGRLQLTTERMREEE EEEEECCHHHHHHHH	30.13	21722762
724	Neddylation	EAIIQIMKMRKKISN HHHHHHHHHHHHCCC	36.86	10092517
724	Ubiquitination	EAIIQIMKMRKKISN HHHHHHHHHHHHCCC	36.86	23000965
727	Ubiquitination	IQIMKMRKKISNAQL HHHHHHHHHCCCHHH	51.46	23000965
728	Ubiquitination	QIMKMRKKISNAQLQ HHHHHHHHCCCHHHH	40.79	23000965
730	Phosphorylation	MKMRKKISNAQLQTE HHHHHHCCCHHHHHH	34.69	19917606
765	Phosphorylation	EWLIEHKYIRRDESD HHHHHCCCCCCCHHH	11.10	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
730	S	Phosphorylation	Kinase	PRKACA	P17612	GPS
730	S	Phosphorylation	Kinase	PKA-FAMILY	-	GPS
730	S	Phosphorylation	Kinase	PKA_GROUP	-	PhosphoELM

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CUL5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CUL5_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ELOB_HUMAN	TCEB2	physical	11384984
ELOC_HUMAN	TCEB1	physical	11384984
LRC41_MOUSE	Lrrc41	physical	11384984
RBX1_MOUSE	Rbx1	physical	11384984
VHL_HUMAN	VHL	physical	11384984
SOCS1_MOUSE	Socs1	physical	11384984
WSB1_MOUSE	Wsb1	physical	11384984
RBX1_HUMAN	RBX1	physical	18805092
RBX1_HUMAN	RBX1	physical	11861641
VIF_HV1B1	vif	physical	16636053
VIF_HV1BR	vif	physical	16636053
VIF_HV1H2	vif	physical	16636053
HS90A_HUMAN	HSP90AA1	physical	19933325
HSP74_HUMAN	HSPA4	physical	19933325
COMD1_HUMAN	COMMD1	physical	21778237
ASB2_HUMAN	ASB2	physical	21119685
ELOB_RAT	Tceb2	physical	19037258
RBX2_MOUSE	Rnf7	physical	19037258
VIF_HV1B1	vif	physical	20532212
VIF_HV1BR	vif	physical	20532212
VIF_HV1H2	vif	physical	20532212
CAND1_HUMAN	CAND1	physical	21249194
RBX1_MOUSE	Rbx1	physical	19037258
ELOC_RAT	Tceb1	physical	19037258
VIF_HV1B1	vif	physical	15574592
VIF_HV1BR	vif	physical	15574592
VIF_HV1H2	vif	physical	15574592
RBX1_HUMAN	RBX1	physical	22405651
CAND1_HUMAN	CAND1	physical	22405651
ELOB_HUMAN	TCEB2	physical	14564014
ELOC_HUMAN	TCEB1	physical	14564014
VIF_HV1B1	vif	physical	14564014
VIF_HV1BR	vif	physical	14564014
VIF_HV1H2	vif	physical	14564014
VIF_HV1B1	vif	physical	19109396
VIF_HV1BR	vif	physical	19109396
VIF_HV1H2	vif	physical	19109396
ELOB_HUMAN	TCEB2	physical	16530799
ELOC_HUMAN	TCEB1	physical	16530799
VIF_HV1B1	vif	physical	16530799
VIF_HV1BR	vif	physical	16530799
VIF_HV1H2	vif	physical	16530799
PEBB_HUMAN	CBFB	physical	22479405
ELOB_HUMAN	TCEB2	physical	22479405
ELOC_HUMAN	TCEB1	physical	22479405
VIF_HV1B1	vif	physical	22479405
VIF_HV1BR	vif	physical	22479405
VIF_HV1H2	vif	physical	22479405
VIF_HV1B1	vif	physical	18499212
VIF_HV1BR	vif	physical	18499212
VIF_HV1H2	vif	physical	18499212
ELOB_HUMAN	TCEB2	physical	17351129
ELOC_HUMAN	TCEB1	physical	17351129
ELOB_HUMAN	TCEB2	physical	15574593
ELOC_HUMAN	TCEB1	physical	15574593
RBX1_HUMAN	RBX1	physical	15574593
ACTB_HUMAN	ACTB	physical	21145461
ACTBL_HUMAN	ACTBL2	physical	21145461
GDE_HUMAN	AGL	physical	21145461
AHSA1_HUMAN	AHSA1	physical	21145461
AIFM1_HUMAN	AIFM1	physical	21145461
ANXA1_HUMAN	ANXA1	physical	21145461
ANX11_HUMAN	ANXA11	physical	21145461
ANXA6_HUMAN	ANXA6	physical	21145461
ANXA7_HUMAN	ANXA7	physical	21145461
ASB1_HUMAN	ASB1	physical	21145461
ASB13_HUMAN	ASB13	physical	21145461
ASB3_HUMAN	ASB3	physical	21145461
ASB6_HUMAN	ASB6	physical	21145461
ASB7_HUMAN	ASB7	physical	21145461
ATD3B_HUMAN	ATAD3B	physical	21145461
ATPA_HUMAN	ATP5A1	physical	21145461
BAG4_HUMAN	BAG4	physical	21145461
BTBD1_HUMAN	BTBD1	physical	21145461
CC184_HUMAN	CCDC184	physical	21145461
CN166_HUMAN	C14orf166	physical	21145461
C1QBP_HUMAN	C1QBP	physical	21145461
TEX35_HUMAN	TEX35	physical	21145461
RTCB_HUMAN	RTCB	physical	21145461
DFFB_HUMAN	DFFB	physical	21145461
CAND1_HUMAN	CAND1	physical	21145461
CARM1_HUMAN	CARM1	physical	21145461
CIRBP_HUMAN	CIRBP	physical	21145461
CLH1_HUMAN	CLTC	physical	21145461
CSN2_HUMAN	COPS2	physical	21145461
CSN3_HUMAN	COPS3	physical	21145461
CSN4_HUMAN	COPS4	physical	21145461
CSN5_HUMAN	COPS5	physical	21145461
CSN6_HUMAN	COPS6	physical	21145461
CSN7A_HUMAN	COPS7A	physical	21145461
CSN7B_HUMAN	COPS7B	physical	21145461
CSN8_HUMAN	COPS8	physical	21145461
YBOX3_HUMAN	YBX3	physical	21145461
PYRG1_HUMAN	CTPS1	physical	21145461
CATD_HUMAN	CTSD	physical	21145461
CUL1_HUMAN	CUL1	physical	21145461
CUL2_HUMAN	CUL2	physical	21145461
CUL3_HUMAN	CUL3	physical	21145461
CUL4A_HUMAN	CUL4A	physical	21145461
CUL4B_HUMAN	CUL4B	physical	21145461
SYDC_HUMAN	DARS	physical	21145461
DAZP1_HUMAN	DAZAP1	physical	21145461
DCTP1_HUMAN	DCTPP1	physical	21145461
DCNL1_HUMAN	DCUN1D1	physical	21145461
DDB1_HUMAN	DDB1	physical	21145461
DDB2_HUMAN	DDB2	physical	21145461
DDX1_HUMAN	DDX1	physical	21145461
DDX56_HUMAN	DDX56	physical	21145461
DDX3X_HUMAN	DDX3X	physical	21145461
DDX5_HUMAN	DDX5	physical	21145461
DHX15_HUMAN	DHX15	physical	21145461
DHX30_HUMAN	DHX30	physical	21145461
DHX9_HUMAN	DHX9	physical	21145461
RRP44_HUMAN	DIS3	physical	21145461
LDHD_HUMAN	LDHD	physical	21145461
DNJA1_HUMAN	DNAJA1	physical	21145461
DNJA3_HUMAN	DNAJA3	physical	21145461
DJC10_HUMAN	DNAJC10	physical	21145461
D19L4_HUMAN	DPY19L4	physical	21145461
EF1A1_HUMAN	EEF1A1	physical	21145461
EF1A2_HUMAN	EEF1A2	physical	21145461
EF1B_HUMAN	EEF1B2	physical	21145461
EF1D_HUMAN	EEF1D	physical	21145461
EF2_HUMAN	EEF2	physical	21145461
U5S1_HUMAN	EFTUD2	physical	21145461
AGO2_HUMAN	AGO2	physical	21145461
AGO3_HUMAN	AGO3	physical	21145461
ELAV1_HUMAN	ELAVL1	physical	21145461
ENOA_HUMAN	ENO1	physical	21145461
ERCC8_HUMAN	ERCC8	physical	21145461
EWS_HUMAN	EWSR1	physical	21145461
FA98A_HUMAN	FAM98A	physical	21145461
FACR1_HUMAN	FAR1	physical	21145461
FBX17_HUMAN	FBXO17	physical	21145461
FBW10_HUMAN	FBXW10	physical	21145461
FCHO1_HUMAN	FCHO1	physical	21145461
FEM1B_HUMAN	FEM1B	physical	21145461
FUS_HUMAN	FUS	physical	21145461
GARS_HUMAN	GARS	physical	21145461
PUR2_HUMAN	GART	physical	21145461
GDIA_HUMAN	GDI1	physical	21145461
GEMI5_HUMAN	GEMIN5	physical	21145461
GLSK_HUMAN	GLS	physical	21145461
GPN1_HUMAN	GPN1	physical	21145461
GPN3_HUMAN	GPN3	physical	21145461
CSN1_HUMAN	GPS1	physical	21145461
GRSF1_HUMAN	GRSF1	physical	21145461
H12_HUMAN	HIST1H1C	physical	21145461
H2B2E_HUMAN	HIST2H2BE	physical	21145461
ROA0_HUMAN	HNRNPA0	physical	21145461
ROA1_HUMAN	HNRNPA1	physical	21145461
ROA2_HUMAN	HNRNPA2B1	physical	21145461
ROA3_HUMAN	HNRNPA3	physical	21145461
ROAA_HUMAN	HNRNPAB	physical	21145461
HNRPC_HUMAN	HNRNPC	physical	21145461
HNRC1_HUMAN	HNRNPCL1	physical	21145461
HNRPD_HUMAN	HNRNPD	physical	21145461
HNRPF_HUMAN	HNRNPF	physical	21145461
HNRH1_HUMAN	HNRNPH1	physical	21145461
HNRH3_HUMAN	HNRNPH3	physical	21145461
HNRPK_HUMAN	HNRNPK	physical	21145461
HNRPR_HUMAN	HNRNPR	physical	21145461
HNRPU_HUMAN	HNRNPU	physical	21145461
HNRL1_HUMAN	HNRNPUL1	physical	21145461
HNRDL_HUMAN	HNRNPDL	physical	21145461
HP1B3_HUMAN	HP1BP3	physical	21145461
HPRT_HUMAN	HPRT1	physical	21145461
HCD2_HUMAN	HSD17B10	physical	21145461
HS90A_HUMAN	HSP90AA1	physical	21145461
HS90B_HUMAN	HSP90AB1	physical	21145461
ENPL_HUMAN	HSP90B1	physical	21145461
HS71L_HUMAN	HSPA1L	physical	21145461
HSP74_HUMAN	HSPA4	physical	21145461
GRP78_HUMAN	HSPA5	physical	21145461
HSP7C_HUMAN	HSPA8	physical	21145461
GRP75_HUMAN	HSPA9	physical	21145461
TOIP2_HUMAN	TOR1AIP2	physical	21145461
IFG15_HUMAN	TOR1AIP2	physical	21145461
IF2B1_HUMAN	IGF2BP1	physical	21145461
ILF2_HUMAN	ILF2	physical	21145461
ILF3_HUMAN	ILF3	physical	21145461
ILK_HUMAN	ILK	physical	21145461
TCPD_HUMAN	CCT4	physical	21145461
FUBP2_HUMAN	KHSRP	physical	21145461
KLDC2_HUMAN	KLHDC2	physical	21145461
KLH42_HUMAN	KLHL42	physical	21145461
KLH15_HUMAN	KLHL15	physical	21145461
KLH18_HUMAN	KLHL18	physical	21145461
K2C1_HUMAN	KRT1	physical	21145461
K1C10_HUMAN	KRT10	physical	21145461
K1C13_HUMAN	KRT13	physical	21145461
K1C14_HUMAN	KRT14	physical	21145461
K22E_HUMAN	KRT2	physical	21145461
K1C24_HUMAN	KRT24	physical	21145461
K2C3_HUMAN	KRT3	physical	21145461
K2C5_HUMAN	KRT5	physical	21145461
K2C6A_HUMAN	KRT6A	physical	21145461
K2C6B_HUMAN	KRT6B	physical	21145461
K2C75_HUMAN	KRT75	physical	21145461
K2C1B_HUMAN	KRT77	physical	21145461
K1C9_HUMAN	KRT9	physical	21145461
LARP1_HUMAN	LARP1	physical	21145461
LDHA_HUMAN	LDHA	physical	21145461
LG3BP_HUMAN	LGALS3BP	physical	21145461
LRC41_HUMAN	LRRC41	physical	21145461
LUZP1_HUMAN	LUZP1	physical	21145461
MA1B1_HUMAN	MAN1B1	physical	21145461
MCM7_HUMAN	MCM7	physical	21145461
RT02_HUMAN	MRPS2	physical	21145461
MUM1_HUMAN	MUM1	physical	21145461
CSN9_HUMAN	MYEOV2	physical	21145461
NAMPT_HUMAN	NAMPT	physical	21145461
NP1L1_HUMAN	NAP1L1	physical	21145461
NP1L4_HUMAN	NAP1L4	physical	21145461
NCBP1_HUMAN	NCBP1	physical	21145461
NUCL_HUMAN	NCL	physical	21145461
NEDD8_HUMAN	NEDD8	physical	21145461
NFKB1_HUMAN	NFKB1	physical	21145461
NKAP_HUMAN	NKAP	physical	21145461
NPM_HUMAN	NPM1	physical	21145461
NSUN2_HUMAN	NSUN2	physical	21145461
NT5D4_HUMAN	NT5DC4	physical	21145461
8ODP_HUMAN	NUDT1	physical	21145461
NUP62_HUMAN	NUP62	physical	21145461
OSMR_HUMAN	OSMR	physical	21145461
PABP1_HUMAN	PABPC1	physical	21145461
PABP4_HUMAN	PABPC4	physical	21145461
PABP2_HUMAN	PABPN1	physical	21145461
PHS_HUMAN	PCBD1	physical	21145461
PCBP1_HUMAN	PCBP1	physical	21145461
PCKGC_HUMAN	PCK1	physical	21145461
PCMD1_HUMAN	PCMTD1	physical	21145461
PCMD2_HUMAN	PCMTD2	physical	21145461
PCNA_HUMAN	PCNA	physical	21145461
PDCD6_HUMAN	PDCD6	physical	21145461
PDIA6_HUMAN	PDIA6	physical	21145461
SERA_HUMAN	PHGDH	physical	21145461
KPYM_HUMAN	PKM	physical	21145461
PLOD1_HUMAN	PLOD1	physical	21145461
PLST_HUMAN	PLS3	physical	21145461
RPB1_HUMAN	POLR2A	physical	21145461
RPB2_HUMAN	POLR2B	physical	21145461
RPB3_HUMAN	POLR2C	physical	21145461
RPB4_HUMAN	POLR2D	physical	21145461
RPB9_HUMAN	POLR2I	physical	21145461
LLR1_HUMAN	LRR1	physical	21145461
PP2AA_HUMAN	PPP2CA	physical	21145461
PRDX1_HUMAN	PRDX1	physical	21145461
PRDX3_HUMAN	PRDX3	physical	21145461
PRKDC_HUMAN	PRKDC	physical	21145461
PRP39_HUMAN	PRPF39	physical	21145461
PTBP1_HUMAN	PTBP1	physical	21145461
QPCT_HUMAN	QPCT	physical	21145461
RB40B_HUMAN	RAB40B	physical	21145461
RB40C_HUMAN	RAB40C	physical	21145461
RBM3_HUMAN	RBM3	physical	21145461
RCBT1_HUMAN	RCBTB1	physical	21145461
RECQ5_HUMAN	RECQL5	physical	21145461
RBX2_HUMAN	RNF7	physical	21145461
MCES_HUMAN	RNMT	physical	21145461
RL10A_HUMAN	RPL10A	physical	21145461
RL11_HUMAN	RPL11	physical	21145461
RL12_HUMAN	RPL12	physical	21145461
RL13A_HUMAN	RPL13A	physical	21145461
RL15_HUMAN	RPL15	physical	21145461
RL18_HUMAN	RPL18	physical	21145461
RL19_HUMAN	RPL19	physical	21145461
RL21_HUMAN	RPL21	physical	21145461
RL22_HUMAN	RPL22	physical	21145461
RL23A_HUMAN	RPL23A	physical	21145461
RL24_HUMAN	RPL24	physical	21145461
RL26L_HUMAN	RPL26L1	physical	21145461
RL27_HUMAN	RPL27	physical	21145461
RL27A_HUMAN	RPL27A	physical	21145461
RL3_HUMAN	RPL3	physical	21145461
RL31_HUMAN	RPL31	physical	21145461
RL35_HUMAN	RPL35	physical	21145461
HNRH2_HUMAN	HNRNPH2	physical	21145461
RL38_HUMAN	RPL38	physical	21145461
RL4_HUMAN	RPL4	physical	21145461
RL5_HUMAN	RPL5	physical	21145461
RL6_HUMAN	RPL6	physical	21145461
RL7_HUMAN	RPL7	physical	21145461
RL8_HUMAN	RPL8	physical	21145461
RLA0_HUMAN	RPLP0	physical	21145461
RLA1_HUMAN	RPLP1	physical	21145461
RLA2_HUMAN	RPLP2	physical	21145461
RS10_HUMAN	RPS10	physical	21145461
RS13_HUMAN	RPS13	physical	21145461
RS14_HUMAN	RPS14	physical	21145461
RS15A_HUMAN	RPS15A	physical	21145461
RS16_HUMAN	RPS16	physical	21145461
RS19_HUMAN	RPS19	physical	21145461
RS2_HUMAN	RPS2	physical	21145461
RS20_HUMAN	RPS20	physical	21145461
RS24_HUMAN	RPS24	physical	21145461
RS25_HUMAN	RPS25	physical	21145461
RS28_HUMAN	RPS28	physical	21145461
RS3_HUMAN	RPS3	physical	21145461
RS3A_HUMAN	RPS3A	physical	21145461
RS4X_HUMAN	RPS4X	physical	21145461
RS5_HUMAN	RPS5	physical	21145461
RS6_HUMAN	RPS6	physical	21145461
RS7_HUMAN	RPS7	physical	21145461
RS8_HUMAN	RPS8	physical	21145461
RS9_HUMAN	RPS9	physical	21145461
RWDD4_HUMAN	RWDD4	physical	21145461
S10A7_HUMAN	S100A7	physical	21145461
S10A9_HUMAN	S100A9	physical	21145461
SAMH1_HUMAN	SAMHD1	physical	21145461
SCFD1_HUMAN	SCFD1	physical	21145461
SDHA_HUMAN	SDHA	physical	21145461
SPB4_HUMAN	SERPINB4	physical	21145461
SRSF2_HUMAN	SRSF2	physical	21145461
SRSF3_HUMAN	SRSF3	physical	21145461
SRSF7_HUMAN	SRSF7	physical	21145461
SKP1_HUMAN	SKP1	physical	21145461
SKP2_HUMAN	SKP2	physical	21145461
ADT2_HUMAN	SLC25A5	physical	21145461
SMCA5_HUMAN	SMARCA5	physical	21145461
U520_HUMAN	SNRNP200	physical	21145461
RU17_HUMAN	SNRNP70	physical	21145461
SNRPA_HUMAN	SNRPA	physical	21145461
RSMB_HUMAN	SNRPB	physical	21145461
RU2B_HUMAN	SNRPB2	physical	21145461
RU1C_HUMAN	SNRPC	physical	21145461
SMD1_HUMAN	SNRPD1	physical	21145461
SMD2_HUMAN	SNRPD2	physical	21145461
SMD3_HUMAN	SNRPD3	physical	21145461
RUXE_HUMAN	SNRPE	physical	21145461
RUXG_HUMAN	SNRPG	physical	21145461
SOCS2_HUMAN	SOCS2	physical	21145461
SOCS4_HUMAN	SOCS4	physical	21145461
SOCS6_HUMAN	SOCS6	physical	21145461
SOCS7_HUMAN	SOCS7	physical	21145461
SPSB3_HUMAN	SPSB3	physical	21145461
SSBP_HUMAN	SSBP1	physical	21145461
SSRD_HUMAN	SSR4	physical	21145461
STK4_HUMAN	STK4	physical	21145461
HNRPQ_HUMAN	SYNCRIP	physical	21145461
RBP56_HUMAN	TAF15	physical	21145461
ELOC_HUMAN	TCEB1	physical	21145461
ELOB_HUMAN	TCEB2	physical	21145461
TFG_HUMAN	TFG	physical	21145461
TIA1_HUMAN	TIA1	physical	21145461
TIAR_HUMAN	TIAL1	physical	21145461
TNKS2_HUMAN	TNKS2	physical	21145461
TOP2A_HUMAN	TOP2A	physical	21145461
TOP2B_HUMAN	TOP2B	physical	21145461
ACD_HUMAN	ACD	physical	21145461
TRA2A_HUMAN	TRA2A	physical	21145461
TRA2B_HUMAN	TRA2B	physical	21145461
TRAP1_HUMAN	TRAP1	physical	21145461
TRI27_HUMAN	TRIM27	physical	21145461
TBA1C_HUMAN	TUBA1C	physical	21145461
TBA4A_HUMAN	TUBA4A	physical	21145461
TBB5_HUMAN	TUBB	physical	21145461
TBB1_HUMAN	TUBB1	physical	21145461
TBB4B_HUMAN	TUBB4B	physical	21145461
TBB4A_HUMAN	TUBB4A	physical	21145461
EFTU_HUMAN	TUFM	physical	21145461
TULP4_HUMAN	TULP4	physical	21145461
U2AF2_HUMAN	U2AF2	physical	21145461
UBC_HUMAN	UBC	physical	21145461
RENT1_HUMAN	UPF1	physical	21145461
REN3B_HUMAN	UPF3B	physical	21145461
DCAF1_HUMAN	VPRBP	physical	21145461
VPS36_HUMAN	VPS36	physical	21145461
DCA11_HUMAN	DCAF11	physical	21145461
DCAF7_HUMAN	DCAF7	physical	21145461
WSB1_HUMAN	WSB1	physical	21145461
WSB2_HUMAN	WSB2	physical	21145461
XPOT_HUMAN	XPOT	physical	21145461
XRCC6_HUMAN	XRCC6	physical	21145461
TUT4_HUMAN	ZCCHC11	physical	21145461
ZN846_HUMAN	ZNF846	physical	21145461
H4_HUMAN	HIST1H4I	physical	21145461
H2A1B_HUMAN	HIST1H2AE	physical	21145461
H2A1J_HUMAN	HIST1H2AJ	physical	21145461
H2A1_HUMAN	HIST1H2AI	physical	21145461
VIF_HV1B1	vif	physical	22379088
VIF_HV1BR	vif	physical	22379088
VIF_HV1H2	vif	physical	22379088
VIF_HV1B1	vif	physical	20592083
VIF_HV1BR	vif	physical	20592083
VIF_HV1H2	vif	physical	20592083
VIF_HV1B1	vif	physical	20220118
VIF_HV1BR	vif	physical	20220118
VIF_HV1H2	vif	physical	20220118
VIF_HV1B1	vif	physical	23098073
VIF_HV1BR	vif	physical	23098073
VIF_HV1H2	vif	physical	23098073
ELOB_HUMAN	TCEB2	physical	23098073
ELOC_HUMAN	TCEB1	physical	23098073
PEBB_HUMAN	CBFB	physical	23098073
SOCS2_HUMAN	SOCS2	physical	23098073
ELOC_HUMAN	TCEB1	physical	23806657
ELOB_HUMAN	TCEB2	physical	23806657
ASB9_HUMAN	ASB9	physical	23806657
SOX30_HUMAN	SOX30	physical	21988832
PTN5_HUMAN	PTPN5	physical	21988832
ARI2_HUMAN	ARIH2	physical	24076655
ELOC_HUMAN	TCEB1	physical	24076655
ELOB_HUMAN	TCEB2	physical	24076655
RBX2_HUMAN	RNF7	physical	24076655
PDE12_HUMAN	PDE12	physical	22863883
SAE1_HUMAN	SAE1	physical	22863883
GLYM_HUMAN	SHMT2	physical	22863883
TPD54_HUMAN	TPD52L2	physical	22863883
UBQL2_HUMAN	UBQLN2	physical	22863883
UN13D_HUMAN	UNC13D	physical	22863883
WDR4_HUMAN	WDR4	physical	22863883
PEBB_HUMAN	CBFB	physical	24390335
ELOB_HUMAN	TCEB2	physical	24390335
ELOC_HUMAN	TCEB1	physical	24390335
VIF_HV1B1	vif	physical	24390335
VIF_HV1BR	vif	physical	24390335
VIF_HV1H2	vif	physical	24390335
PEBB_HUMAN	CBFB	physical	24390320
ELOB_HUMAN	TCEB2	physical	24390320
ELOC_HUMAN	TCEB1	physical	24390320
VIF_HV1B1	vif	physical	24390320
VIF_HV1BR	vif	physical	24390320
VIF_HV1H2	vif	physical	24390320
PEBB_HUMAN	CBFB	physical	24402281
ELOB_HUMAN	TCEB2	physical	24402281
ELOC_HUMAN	TCEB1	physical	24402281
VIF_HV1B1	vif	physical	24402281
VIF_HV1BR	vif	physical	24402281
VIF_HV1H2	vif	physical	24402281
CUL3_HUMAN	CUL3	physical	22709582
RBX2_HUMAN	RNF7	physical	25416956
CCDB1_HUMAN	CCNDBP1	physical	25416956
LTP_EBVB9	BPLF1	physical	22474075
DPTOR_HUMAN	DEPTOR	physical	25499913
ELOB_HUMAN	TCEB2	physical	25499913
RBX2_HUMAN	RNF7	physical	21516116
GHR_HUMAN	GHR	physical	25505247
RBX2_HUMAN	RNF7	physical	25505247
RBX1_HUMAN	RBX1	physical	25912140
RBX2_HUMAN	RNF7	physical	25912140
SOCS3_HUMAN	SOCS3	physical	24438103
ELOB_HUMAN	TCEB2	physical	24438103
ELOC_HUMAN	TCEB1	physical	24438103
TRAF6_HUMAN	TRAF6	physical	27233966
WSB1_HUMAN	WSB1	physical	28514442
SOCS7_HUMAN	SOCS7	physical	28514442
TULP4_HUMAN	TULP4	physical	28514442
ASB1_HUMAN	ASB1	physical	28514442
RB40C_HUMAN	RAB40C	physical	28514442
TOP2B_HUMAN	TOP2B	physical	28514442
SOCS5_HUMAN	SOCS5	physical	28514442
PCMD1_HUMAN	PCMTD1	physical	28514442
SPSB3_HUMAN	SPSB3	physical	28514442
LRC41_HUMAN	LRRC41	physical	28514442
ASB13_HUMAN	ASB13	physical	28514442
LRC58_HUMAN	LRRC58	physical	28514442
FEM1B_HUMAN	FEM1B	physical	28514442
RN187_HUMAN	RNF187	physical	28514442
FEM1A_HUMAN	FEM1A	physical	28514442
SOCS4_HUMAN	SOCS4	physical	28514442
FEM1C_HUMAN	FEM1C	physical	28514442
PCMD2_HUMAN	PCMTD2	physical	28514442
RBX2_HUMAN	RNF7	physical	28514442
MAP2_HUMAN	METAP2	physical	28514442
ELOC_HUMAN	TCEB1	physical	28514442
SPSB4_HUMAN	SPSB4	physical	28514442
KLDC3_HUMAN	KLHDC3	physical	28514442
NEDD8_HUMAN	NEDD8	physical	28514442
CAND1_HUMAN	CAND1	physical	28514442
FBW1A_HUMAN	BTRC	physical	27910872
RBX2_HUMAN	RNF7	physical	27910872
NEDD8_HUMAN	NEDD8	physical	28522566
RBX2_HUMAN	RNF7	physical	27591266
UBE2F_HUMAN	UBE2F	physical	27591266
APR_HUMAN	PMAIP1	physical	27591266

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CUL5_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-210, AND MASSSPECTROMETRY.	18669648 [Abstract]