dbPTM

GLYM_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GLYM_HUMAN
UniProt AC	P34897
Protein Name	Serine hydroxymethyltransferase, mitochondrial
Gene Name	SHMT2 {ECO:0000312\|HGNC:HGNC:10852}
Organism	Homo sapiens (Human).
Sequence Length	504
Subcellular Localization	Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid . Mitochondrion inner membrane . Cytoplasm . Nucleus . Mainly localizes in the mitochondrion. Also found in the cytoplasm and nucleus as part of the BRISC complex (PubMed:24075985).
Protein Description	Catalyzes the cleavage of serine to glycine accompanied with the production of 5,10-methylenetetrahydrofolate, an essential intermediate for purine biosynthesis. [PubMed: 24075985]
Protein Sequence	MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDEH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MLYFSLFWAA -----CCHHHHHHHH	6.99	-
44	Phosphorylation	GEANRGWTGQESLSD CCCCCCCCCCCCCCC	31.63	28857561
48	Phosphorylation	RGWTGQESLSDSDPE CCCCCCCCCCCCCHH	25.86	28857561
50	Phosphorylation	WTGQESLSDSDPEMW CCCCCCCCCCCHHHH	44.33	29507054
52	Phosphorylation	GQESLSDSDPEMWEL CCCCCCCCCHHHHHH	52.25	27251275
74	Ubiquitination	QCRGLELIASENFCS HCCCHHHHHCCCCHH	2.64	21890473
90	Phosphorylation	AALEALGSCLNNKYS HHHHHHHHHHHCCCC	19.11	28152594
95	2-Hydroxyisobutyrylation	LGSCLNNKYSEGYPG HHHHHHCCCCCCCCC	49.43	-
95	Acetylation	LGSCLNNKYSEGYPG HHHHHHCCCCCCCCC	49.43	25953088
95	Ubiquitination	LGSCLNNKYSEGYPG HHHHHHCCCCCCCCC	49.43	21890473
95	Ubiquitination	LGSCLNNKYSEGYPG HHHHHHCCCCCCCCC	49.43	21890473
96	Phosphorylation	GSCLNNKYSEGYPGK HHHHHCCCCCCCCCC	17.68	28152594
97	Phosphorylation	SCLNNKYSEGYPGKR HHHHCCCCCCCCCCC	26.59	28152594
100	Phosphorylation	NNKYSEGYPGKRYYG HCCCCCCCCCCCCCC	12.54	28152594
103	2-Hydroxyisobutyrylation	YSEGYPGKRYYGGAE CCCCCCCCCCCCCHH	32.49	-
103	Acetylation	YSEGYPGKRYYGGAE CCCCCCCCCCCCCHH	32.49	19608861
103	Malonylation	YSEGYPGKRYYGGAE CCCCCCCCCCCCCHH	32.49	26320211
103	Ubiquitination	YSEGYPGKRYYGGAE CCCCCCCCCCCCCHH	32.49	19608861
144	Phosphorylation	NVQPYSGSPANLAVY CCCCCCCCCHHHHHH	18.20	25627689
173	Phosphorylation	LPDGGHLTHGYMSDV CCCCCCCCCCCHHCC	13.95	21406692
176	Phosphorylation	GGHLTHGYMSDVKRI CCCCCCCCHHCCEEE	5.95	21406692
178	Phosphorylation	HLTHGYMSDVKRISA CCCCCCHHCCEEEEE	30.67	20068231
179	Ubiquitination	LTHGYMSDVKRISAT CCCCCHHCCEEEEEE	33.17	21890473
181	Acetylation	HGYMSDVKRISATSI CCCHHCCEEEEEEEE	49.34	19608861
181	Malonylation	HGYMSDVKRISATSI CCCHHCCEEEEEEEE	49.34	26320211
181	Ubiquitination	HGYMSDVKRISATSI CCCHHCCEEEEEEEE	49.34	21906983
184	Phosphorylation	MSDVKRISATSIFFE HHCCEEEEEEEEEEE	29.53	28348404
186	Phosphorylation	DVKRISATSIFFESM CCEEEEEEEEEEECC	18.63	28857561
187	Phosphorylation	VKRISATSIFFESMP CEEEEEEEEEEECCC	19.67	28857561
192	Phosphorylation	ATSIFFESMPYKLNP EEEEEEECCCCCCCC	21.65	28857561
196	Acetylation	FFESMPYKLNPKTGL EEECCCCCCCCCCCC	35.60	19608861
196	Ubiquitination	FFESMPYKLNPKTGL EEECCCCCCCCCCCC	35.60	-
200	2-Hydroxyisobutyrylation	MPYKLNPKTGLIDYN CCCCCCCCCCCCCHH	54.90	-
200	Acetylation	MPYKLNPKTGLIDYN CCCCCCCCCCCCCHH	54.90	23954790
200	Malonylation	MPYKLNPKTGLIDYN CCCCCCCCCCCCCHH	54.90	26320211
200	Ubiquitination	MPYKLNPKTGLIDYN CCCCCCCCCCCCCHH	54.90	21890473
201	Phosphorylation	PYKLNPKTGLIDYNQ CCCCCCCCCCCCHHH	38.18	28152594
206	Phosphorylation	PKTGLIDYNQLALTA CCCCCCCHHHHHHHH	9.60	28152594
212	Phosphorylation	DYNQLALTARLFRPR CHHHHHHHHHHHCCC	12.25	28152594
225	Phosphorylation	PRLIIAGTSAYARLI CCEEEECCHHHHHHH	10.93	28152594
226	Phosphorylation	RLIIAGTSAYARLID CEEEECCHHHHHHHH	20.54	28152594
228	Phosphorylation	IIAGTSAYARLIDYA EEECCHHHHHHHHHH	7.63	28152594
230	Methylation	AGTSAYARLIDYARM ECCHHHHHHHHHHHH	21.35	115916929
236	Methylation	ARLIDYARMREVCDE HHHHHHHHHHHHHHH	20.61	115916933
245	Acetylation	REVCDEVKAHLLADM HHHHHHHHHHHHHHH	28.21	25825284
259	Acetylation	MAHISGLVAAKVIPS HHHHHHHHHHHHCCC	5.78	19608861
262	Ubiquitination	ISGLVAAKVIPSPFK HHHHHHHHHCCCCCC	30.84	-
266	Phosphorylation	VAAKVIPSPFKHADI HHHHHCCCCCCCCCE	31.67	30266825
269	Acetylation	KVIPSPFKHADIVTT HHCCCCCCCCCEEEE	41.07	23954790
269	Malonylation	KVIPSPFKHADIVTT HHCCCCCCCCCEEEE	41.07	26320211
269	Methylation	KVIPSPFKHADIVTT HHCCCCCCCCCEEEE	41.07	22634763
269	Succinylation	KVIPSPFKHADIVTT HHCCCCCCCCCEEEE	41.07	27452117
269	Ubiquitination	KVIPSPFKHADIVTT HHCCCCCCCCCEEEE	41.07	19608861
275	Phosphorylation	FKHADIVTTTTHKTL CCCCCEEEECCCHHH	20.82	28152594
276	Phosphorylation	KHADIVTTTTHKTLR CCCCEEEECCCHHHH	20.85	28152594
277	Phosphorylation	HADIVTTTTHKTLRG CCCEEEECCCHHHHC	19.96	28152594
278	Phosphorylation	ADIVTTTTHKTLRGA CCEEEECCCHHHHCC	21.20	28152594
280	N6-(pyridoxal phosphate)lysine	IVTTTTHKTLRGARS EEEECCCHHHHCCCC	47.35	-
280	2-Hydroxyisobutyrylation	IVTTTTHKTLRGARS EEEECCCHHHHCCCC	47.35	-
280	Acetylation	IVTTTTHKTLRGARS EEEECCCHHHHCCCC	47.35	26051181
280	Malonylation	IVTTTTHKTLRGARS EEEECCCHHHHCCCC	47.35	26320211
280	Other	IVTTTTHKTLRGARS EEEECCCHHHHCCCC	47.35	29364879
280	Succinylation	IVTTTTHKTLRGARS EEEECCCHHHHCCCC	47.35	29180469
280	Ubiquitination	IVTTTTHKTLRGARS EEEECCCHHHHCCCC	47.35	21906983
287	Acetylation	KTLRGARSGLIFYRK HHHHCCCCEEEEEEC	37.10	19608861
297	Acetylation	IFYRKGVKAVDPKTG EEEECCCCEECCCCC	51.89	19608861
297	Ubiquitination	IFYRKGVKAVDPKTG EEEECCCCEECCCCC	51.89	19608861
302	Acetylation	GVKAVDPKTGREIPY CCCEECCCCCCCCCC	60.18	23749302
302	Succinylation	GVKAVDPKTGREIPY CCCEECCCCCCCCCC	60.18	27452117
346	Acetylation	LKQACTPMFREYSLQ HHHHCCHHHHHHHHH	2.39	19608861
346	Ubiquitination	LKQACTPMFREYSLQ HHHHCCHHHHHHHHH	2.39	19608861
350	Phosphorylation	CTPMFREYSLQVLKN CCHHHHHHHHHHHHH	15.49	28152594
351	Phosphorylation	TPMFREYSLQVLKNA CHHHHHHHHHHHHHH	13.94	28152594
356	2-Hydroxyisobutyrylation	EYSLQVLKNARAMAD HHHHHHHHHHHHHHH	50.10	-
356	Acetylation	EYSLQVLKNARAMAD HHHHHHHHHHHHHHH	50.10	19608861
356	Malonylation	EYSLQVLKNARAMAD HHHHHHHHHHHHHHH	50.10	26320211
356	Ubiquitination	EYSLQVLKNARAMAD HHHHHHHHHHHHHHH	50.10	19608861
361	Sulfoxidation	VLKNARAMADALLER HHHHHHHHHHHHHHC	2.64	21406390
368	Methylation	MADALLERGYSLVSG HHHHHHHCCCEEECC	49.68	115916937
370	Phosphorylation	DALLERGYSLVSGGT HHHHHCCCEEECCCC	12.68	28152594
371	Phosphorylation	ALLERGYSLVSGGTD HHHHCCCEEECCCCC	25.72	28152594
389	2-Hydroxyisobutyrylation	VLVDLRPKGLDGARA EEEECCCCCCCHHHH	66.72	-
389	Acetylation	VLVDLRPKGLDGARA EEEECCCCCCCHHHH	66.72	27452117
389	Ubiquitination	VLVDLRPKGLDGARA EEEECCCCCCCHHHH	66.72	-
404	Phosphorylation	ERVLELVSITANKNT HHHHHHEEEECCCCC	27.18	21712546
406	Phosphorylation	VLELVSITANKNTCP HHHHEEEECCCCCCC	19.37	28851738
409	2-Hydroxyisobutyrylation	LVSITANKNTCPGDR HEEEECCCCCCCCCC	51.69	-
409	Acetylation	LVSITANKNTCPGDR HEEEECCCCCCCCCC	51.69	25953088
409	Malonylation	LVSITANKNTCPGDR HEEEECCCCCCCCCC	51.69	26320211
409	Ubiquitination	LVSITANKNTCPGDR HEEEECCCCCCCCCC	51.69	-
416	Methylation	KNTCPGDRSAITPGG CCCCCCCCCCCCCCC	33.62	115916941
417	Phosphorylation	NTCPGDRSAITPGGL CCCCCCCCCCCCCCE	28.85	30266825
420	Phosphorylation	PGDRSAITPGGLRLG CCCCCCCCCCCEECC	18.65	30266825
442	Methylation	QFREDDFRRVVDFID CCCCCHHHHHHHHHH	37.16	115916945
448	Ubiquitination	FRRVVDFIDEGVNIG HHHHHHHHHHCCCEE	4.00	21890473
453	Ubiquitination	DFIDEGVNIGLEVKS HHHHHCCCEECEECC	33.20	21890473
454	Acetylation	FIDEGVNIGLEVKSK HHHHCCCEECEECCC	6.56	19608861
459	2-Hydroxyisobutyrylation	VNIGLEVKSKTAKLQ CCEECEECCCCCCHH	36.54	-
459	Acetylation	VNIGLEVKSKTAKLQ CCEECEECCCCCCHH	36.54	19608861
459	Ubiquitination	VNIGLEVKSKTAKLQ CCEECEECCCCCCHH	36.54	19608861
459	Ubiquitination	VNIGLEVKSKTAKLQ CCEECEECCCCCCHH	36.54	21890473
464	2-Hydroxyisobutyrylation	EVKSKTAKLQDFKSF EECCCCCCHHHHHHH	52.49	-
464	Acetylation	EVKSKTAKLQDFKSF EECCCCCCHHHHHHH	52.49	19608861
464	Malonylation	EVKSKTAKLQDFKSF EECCCCCCHHHHHHH	52.49	26320211
464	Ubiquitination	EVKSKTAKLQDFKSF EECCCCCCHHHHHHH	52.49	19608861
464	Ubiquitination	EVKSKTAKLQDFKSF EECCCCCCHHHHHHH	52.49	21890473
469	"N6,N6-dimethyllysine"	TAKLQDFKSFLLKDS CCCHHHHHHHHHCCC	48.89	-
469	2-Hydroxyisobutyrylation	TAKLQDFKSFLLKDS CCCHHHHHHHHHCCC	48.89	-
469	Acetylation	TAKLQDFKSFLLKDS CCCHHHHHHHHHCCC	48.89	19608861
469	Methylation	TAKLQDFKSFLLKDS CCCHHHHHHHHHCCC	48.89	-
469	Ubiquitination	TAKLQDFKSFLLKDS CCCHHHHHHHHHCCC	48.89	21890473
470	Phosphorylation	AKLQDFKSFLLKDSE CCHHHHHHHHHCCCH	22.56	23312004
474	Acetylation	DFKSFLLKDSETSQR HHHHHHHCCCHHHHH	62.45	19608861
474	Malonylation	DFKSFLLKDSETSQR HHHHHHHCCCHHHHH	62.45	26320211
474	Ubiquitination	DFKSFLLKDSETSQR HHHHHHHCCCHHHHH	62.45	21890473

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GLYM_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
280	K	Succinylation		29180469
Succinylation at Lys-280 inhibits the hydroxymethyltransferase activity.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GLYM_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
ACPH_HUMAN	APEH	physical	22863883
CAND1_HUMAN	CAND1	physical	22863883
SRC8_HUMAN	CTTN	physical	22863883
ERF3B_HUMAN	GSPT2	physical	22863883
IDE_HUMAN	IDE	physical	22863883
NASP_HUMAN	NASP	physical	22863883
SNX6_HUMAN	SNX6	physical	22863883
AR6P1_HUMAN	ARL6IP1	physical	25416956
CKLF5_HUMAN	CMTM5	physical	25416956
NOC2L_HUMAN	NOC2L	physical	22658674
HES4_HUMAN	HES4	physical	22658674
MTOR_HUMAN	MTOR	physical	22658674
UBR4_HUMAN	UBR4	physical	22658674
HP1B3_HUMAN	HP1BP3	physical	22658674
E2F2_HUMAN	E2F2	physical	22658674
RSRP1_HUMAN	RSRP1	physical	22658674
ARI1A_HUMAN	ARID1A	physical	22658674
M3K6_HUMAN	MAP3K6	physical	22658674
RCC1_HUMAN	RCC1	physical	22658674
ARCH_HUMAN	ZBTB8OS	physical	22658674
SYYC_HUMAN	YARS	physical	22658674
K0754_HUMAN	KIAA0754	physical	22658674
BMP8B_HUMAN	BMP8B	physical	22658674
SZT2_HUMAN	SZT2	physical	22658674
LRC42_HUMAN	LRRC42	physical	22658674
RM37_HUMAN	MRPL37	physical	22658674
DNJB4_HUMAN	DNAJB4	physical	22658674
KAT3_HUMAN	CCBL2	physical	22658674
FBP1L_HUMAN	FNBP1L	physical	22658674
PALMD_HUMAN	PALMD	physical	22658674
STRP1_HUMAN	STRIP1	physical	22658674
NT2NL_HUMAN	NOTCH2NL	physical	22658674
RT21_HUMAN	MRPS21	physical	22658674
GLP3L_HUMAN	GOLPH3L	physical	22658674
PRUN1_HUMAN	PRUNE	physical	22658674
S10AB_HUMAN	S100A11	physical	22658674
TPM3_HUMAN	TPM3	physical	22658674
BLOM7_HUMAN	KIAA0907	physical	22658674
LMNA_HUMAN	LMNA	physical	22658674
MEF2D_HUMAN	MEF2D	physical	22658674
COPA_HUMAN	COPA	physical	22658674
NDUS2_HUMAN	NDUFS2	physical	22658674
RBG10_HUMAN	RABGAP1L	physical	22658674
RBG1L_HUMAN	RABGAP1L	physical	22658674
CA021_HUMAN	C1orf21	physical	22658674
LIN9_HUMAN	LIN9	physical	22658674
PARP1_HUMAN	PARP1	physical	22658674
ELYS_HUMAN	AHCTF1	physical	22658674
F110C_HUMAN	FAM110C	physical	22658674
PTRD1_HUMAN	PTRHD1	physical	22658674
GPT11_HUMAN	GPATCH11	physical	22658674
LPPRC_HUMAN	LRPPRC	physical	22658674
CMKMT_HUMAN	CAMKMT	physical	22658674
FBLN3_HUMAN	EFEMP1	physical	22658674
MEIS1_HUMAN	MEIS1	physical	22658674
RPA1_HUMAN	POLR1A	physical	22658674
COX5B_HUMAN	COX5B	physical	22658674
PDCL3_HUMAN	PDCL3	physical	22658674
NPAS2_HUMAN	NPAS2	physical	22658674
BIN1_HUMAN	BIN1	physical	22658674
IWS1_HUMAN	IWS1	physical	22658674
NAB1_HUMAN	NAB1	physical	22658674
F117B_HUMAN	FAM117B	physical	22658674
ABI2_HUMAN	ABI2	physical	22658674
CO4A3_HUMAN	COL4A3	physical	22658674
HJURP_HUMAN	HJURP	physical	22658674
ATG4B_HUMAN	ATG4B	physical	22658674
ZN860_HUMAN	ZNF860	physical	22658674
RBM6_HUMAN	RBM6	physical	22658674
ARHG3_HUMAN	ARHGEF3	physical	22658674
THOC7_HUMAN	THOC7	physical	22658674
CCD58_HUMAN	CCDC58	physical	22658674
ISY1_HUMAN	ISY1	physical	22658674
MBD4_HUMAN	MBD4	physical	22658674
RYK_HUMAN	RYK	physical	22658674
RT22_HUMAN	MRPS22	physical	22658674
ACL6A_HUMAN	ACTL6A	physical	22658674
MRP5_HUMAN	ABCC5	physical	22658674
XXLT1_HUMAN	XXYLT1	physical	22658674
DGKQ_HUMAN	DGKQ	physical	22658674
EVC_HUMAN	EVC	physical	22658674
GRPE1_HUMAN	GRPEL1	physical	22658674
MED28_HUMAN	MED28	physical	22658674
OCAD1_HUMAN	OCIAD1	physical	22658674
SC31A_HUMAN	SEC31A	physical	22658674
RT18C_HUMAN	MRPS18C	physical	22658674
WDFY3_HUMAN	WDFY3	physical	22658674
HERC3_HUMAN	HERC3	physical	22658674
FAT4_HUMAN	FAT4	physical	22658674
HMGB2_HUMAN	HMGB2	physical	22658674
TFIP8_HUMAN	TNFAIP8	physical	22658674
RPGF6_HUMAN	RAPGEF6	physical	22658674
HSP74_HUMAN	HSPA4	physical	22658674
GRP75_HUMAN	HSPA9	physical	22658674
SYHM_HUMAN	HARS2	physical	22658674
FBX38_HUMAN	FBXO38	physical	22658674
STK10_HUMAN	STK10	physical	22658674
UIMC1_HUMAN	UIMC1	physical	22658674
GRK6_HUMAN	GRK6	physical	22658674
PDLI7_HUMAN	PDLIM7	physical	22658674
DDX41_HUMAN	DDX41	physical	22658674
ROAA_HUMAN	HNRNPAB	physical	22658674
EXOC2_HUMAN	EXOC2	physical	22658674
BPHL_HUMAN	BPHL	physical	22658674
SYFM_HUMAN	FARS2	physical	22658674
TBCD7_HUMAN	TBC1D7	physical	22658674
R144B_HUMAN	RNF144B	physical	22658674
H2A1B_HUMAN	HIST1H2AE	physical	22658674
H4_HUMAN	HIST1H4I	physical	22658674
H2B1O_HUMAN	HIST1H2BO	physical	22658674
PBX2_HUMAN	PBX2	physical	22658674
ZNF76_HUMAN	ZNF76	physical	22658674
NFYA_HUMAN	NFYA	physical	22658674
RT10_HUMAN	MRPS10	physical	22658674
TREF1_HUMAN	TRERF1	physical	22658674
TTK_HUMAN	TTK	physical	22658674
SNX14_HUMAN	SNX14	physical	22658674
ZUFSP_HUMAN	ZUFSP	physical	22658674
INGR1_HUMAN	IFNGR1	physical	22658674
HEBP2_HUMAN	HEBP2	physical	22658674
FBX5_HUMAN	FBXO5	physical	22658674
SCAF8_HUMAN	SCAF8	physical	22658674
TFB1M_HUMAN	TFB1M	physical	22658674
WDR27_HUMAN	WDR27	physical	22658674
SNX8_HUMAN	SNX8	physical	22658674
NOD1_HUMAN	NOD1	physical	22658674
RPC9_HUMAN	CRCP	physical	22658674
GATD1_HUMAN	GATAD1	physical	22658674
SAMD9_HUMAN	SAMD9	physical	22658674
PTCD1_HUMAN	PTCD1	physical	22658674
TRIP6_HUMAN	TRIP6	physical	22658674
MPPB_HUMAN	PMPCB	physical	22658674
PRS7_HUMAN	PSMC2	physical	22658674
COPG2_HUMAN	COPG2	physical	22658674
NU205_HUMAN	NUP205	physical	22658674
ABCF2_HUMAN	ABCF2	physical	22658674
DEMA_HUMAN	DMTN	physical	22658674
BIN3_HUMAN	BIN3	physical	22658674
T2EB_HUMAN	GTF2E2	physical	22658674
MTFR1_HUMAN	MTFR1	physical	22658674
STAU2_HUMAN	STAU2	physical	22658674
GDAP1_HUMAN	GDAP1	physical	22658674
RIPK2_HUMAN	RIPK2	physical	22658674
DECR_HUMAN	DECR1	physical	22658674
PKHF2_HUMAN	PLEKHF2	physical	22658674
1433Z_HUMAN	YWHAZ	physical	22658674
UTP23_HUMAN	UTP23	physical	22658674
ZN623_HUMAN	ZNF623	physical	22658674
SCRIB_HUMAN	SCRIB	physical	22658674
KANK1_HUMAN	KANK1	physical	22658674
PUM3_HUMAN	KIAA0020	physical	22658674
KDM4C_HUMAN	KDM4C	physical	22658674
MPDZ_HUMAN	MPDZ	physical	22658674
ACOC_HUMAN	ACO1	physical	22658674
NFX1_HUMAN	NFX1	physical	22658674
UBAP1_HUMAN	UBAP1	physical	22658674
TLN1_HUMAN	TLN1	physical	22658674
CREB3_HUMAN	CREB3	physical	22658674
HINT2_HUMAN	HINT2	physical	22658674
CI040_HUMAN	C9orf40	physical	22658674
NOL8_HUMAN	NOL8	physical	22658674
SIAS_HUMAN	NANS	physical	22658674
CP110_HUMAN	CCP110	physical	22658674
TTL11_HUMAN	TTLL11	physical	22658674
GRP78_HUMAN	HSPA5	physical	22658674
KAT1_HUMAN	CCBL1	physical	22658674
FNBP1_HUMAN	FNBP1	physical	22658674
DPH7_HUMAN	DPH7	physical	22658674
US6NL_HUMAN	USP6NL	physical	22658674
SKT_HUMAN	KIAA1217	physical	22658674
CUL2_HUMAN	CUL2	physical	22658674
BMS1_HUMAN	BMS1	physical	22658674
HERC4_HUMAN	HERC4	physical	22658674
DNA2_HUMAN	DNA2	physical	22658674
AGA11_HUMAN	AGAP11	physical	22658674
P5CS_HUMAN	ALDH18A1	physical	22658674
AATC_HUMAN	GOT1	physical	22658674
CJ076_HUMAN	C10orf76	physical	22658674
BBIP1_HUMAN	BBIP1	physical	22658674
DNHD1_HUMAN	DNHD1	physical	22658674
ILK_HUMAN	ILK	physical	22658674
ZN215_HUMAN	ZNF215	physical	22658674
COPB_HUMAN	COPB1	physical	22658674
ELP4_HUMAN	ELP4	physical	22658674
MADD_HUMAN	MADD	physical	22658674
PRS6A_HUMAN	PSMC3	physical	22658674
NDUS3_HUMAN	NDUFS3	physical	22658674
CPSF7_HUMAN	CPSF7	physical	22658674
FEN1_HUMAN	FEN1	physical	22658674
SSH3_HUMAN	SSH3	physical	22658674
TR19L_HUMAN	RELT	physical	22658674
ANR49_HUMAN	ANKRD49	physical	22658674
AMOL1_HUMAN	AMOTL1	physical	22658674
ENDD1_HUMAN	ENDOD1	physical	22658674
IL18_HUMAN	IL18	physical	22658674
CE164_HUMAN	CEP164	physical	22658674
VPS11_HUMAN	VPS11	physical	22658674
HINFP_HUMAN	HINFP	physical	22658674
FXRD1_HUMAN	FOXRED1	physical	22658674
CPNE8_HUMAN	CPNE8	physical	22658674
KI21A_HUMAN	KIF21A	physical	22658674
PPHLN_HUMAN	PPHLN1	physical	22658674
HDAC7_HUMAN	HDAC7	physical	22658674
LIMA1_HUMAN	LIMA1	physical	22658674
RAB5B_HUMAN	RAB5B	physical	22658674
SMRC2_HUMAN	SMARCC2	physical	22658674
CISY_HUMAN	CS	physical	22658674
SPRY4_HUMAN	SPRYD4	physical	22658674
INHBE_HUMAN	INHBE	physical	22658674
RASF9_HUMAN	RASSF9	physical	22658674
NET4_HUMAN	NTN4	physical	22658674
APAF_HUMAN	APAF1	physical	22658674
PAXI_HUMAN	PXN	physical	22658674
RNF10_HUMAN	RNF10	physical	22658674
USPL1_HUMAN	USPL1	physical	22658674
INT6_HUMAN	INTS6	physical	22658674
PIBF1_HUMAN	PIBF1	physical	22658674
RAP2A_HUMAN	RAP2A	physical	22658674
GCP3_HUMAN	TUBGCP3	physical	22658674
PCID2_HUMAN	PCID2	physical	22658674
MLH3_HUMAN	MLH3	physical	22658674
FLVC2_HUMAN	FLVCR2	physical	22658674
TF2AA_HUMAN	GTF2A1	physical	22658674
DDX24_HUMAN	DDX24	physical	22658674
BTBD6_HUMAN	BTBD6	physical	22658674
AQR_HUMAN	AQR	physical	22658674
SKAP_HUMAN	KNSTRN	physical	22658674
CHP1_HUMAN	CHP1	physical	22658674
ADAL_HUMAN	ADAL	physical	22658674
TP53B_HUMAN	TP53BP1	physical	22658674
TMOD2_HUMAN	TMOD2	physical	22658674
HTF4_HUMAN	TCF12	physical	22658674
MYO1E_HUMAN	MYO1E	physical	22658674
HM20A_HUMAN	HMG20A	physical	22658674
RHDF1_HUMAN	RHBDF1	physical	22658674
CLUA1_HUMAN	CLUAP1	physical	22658674
LEUK_HUMAN	SPN	physical	22658674
CC189_HUMAN	C16orf93	physical	22658674
FTM_HUMAN	RPGRIP1L	physical	22658674
AR2BP_HUMAN	ARL2BP	physical	22658674
NTF2_HUMAN	NUTF2	physical	22658674
EDC4_HUMAN	EDC4	physical	22658674
NFAC3_HUMAN	NFATC3	physical	22658674
PDPR_HUMAN	PDPR	physical	22658674
PRP16_HUMAN	DHX38	physical	22658674
OSGI1_HUMAN	OSGIN1	physical	22658674
KLDC4_HUMAN	KLHDC4	physical	22658674
PRP8_HUMAN	PRPF8	physical	22658674
WDR81_HUMAN	WDR81	physical	22658674
CHD3_HUMAN	CHD3	physical	22658674
PUR4_HUMAN	PFAS	physical	22658674
PDIP2_HUMAN	POLDIP2	physical	22658674
ALDOC_HUMAN	ALDOC	physical	22658674
MY18A_HUMAN	MYO18A	physical	22658674
COPRS_HUMAN	COPRS	physical	22658674
ZN207_HUMAN	ZNF207	physical	22658674
RPGFL_HUMAN	RAPGEFL1	physical	22658674
5NT3B_HUMAN	NT5C3B	physical	22658674
STAT3_HUMAN	STAT3	physical	22658674
AOC2_HUMAN	AOC2	physical	22658674
DHX8_HUMAN	DHX8	physical	22658674
HEXI1_HUMAN	HEXIM1	physical	22658674
LC7L3_HUMAN	LUC7L3	physical	22658674
SRSF1_HUMAN	SRSF1	physical	22658674
MKS1_HUMAN	MKS1	physical	22658674
MET2A_HUMAN	METTL2A	physical	22658674
STRAA_HUMAN	STRADA	physical	22658674
S30BP_HUMAN	SAP30BP	physical	22658674
EXOC7_HUMAN	EXOC7	physical	22658674
JMJD6_HUMAN	JMJD6	physical	22658674
TBC16_HUMAN	TBC1D16	physical	22658674
HGS_HUMAN	HGS	physical	22658674
NDC80_HUMAN	NDC80	physical	22658674
F210A_HUMAN	FAM210A	physical	22658674
TT39C_HUMAN	TTC39C	physical	22658674
ELP2_HUMAN	ELP2	physical	22658674
MBD1_HUMAN	MBD1	physical	22658674
PIGN_HUMAN	PIGN	physical	22658674
ADNP2_HUMAN	ADNP2	physical	22658674
WDR18_HUMAN	WDR18	physical	22658674
GIPC3_HUMAN	GIPC3	physical	22658674
HNRPM_HUMAN	HNRNPM	physical	22658674
TYK2_HUMAN	TYK2	physical	22658674
RNH2A_HUMAN	RNASEH2A	physical	22658674
AKP8L_HUMAN	AKAP8L	physical	22658674
RAB8A_HUMAN	RAB8A	physical	22658674
UN13A_HUMAN	UNC13A	physical	22658674
CRLF1_HUMAN	CRLF1	physical	22658674
COPE_HUMAN	COPE	physical	22658674
RFXK_HUMAN	RFXANK	physical	22658674
ZN792_HUMAN	ZNF792	physical	22658674
SPT5H_HUMAN	SUPT5H	physical	22658674
AT1A3_HUMAN	ATP1A3	physical	22658674
CADM4_HUMAN	CADM4	physical	22658674
PPP5_HUMAN	PPP5C	physical	22658674
STRN4_HUMAN	STRN4	physical	22658674
ANM1_HUMAN	PRMT1	physical	22658674
ZN419_HUMAN	ZNF419	physical	22658674
ZN544_HUMAN	ZNF544	physical	22658674
ZNF8_HUMAN	ZNF8	physical	22658674
A1BG_HUMAN	A1BG	physical	22658674
NOP56_HUMAN	NOP56	physical	22658674
ITPA_HUMAN	ITPA	physical	22658674
XRN2_HUMAN	XRN2	physical	22658674
RALY_HUMAN	RALY	physical	22658674
CP250_HUMAN	CEP250	physical	22658674
ZNFX1_HUMAN	ZNFX1	physical	22658674
GMEB2_HUMAN	GMEB2	physical	22658674
BACH1_HUMAN	BACH1	physical	22658674
QORL1_HUMAN	CRYZL1	physical	22658674
NDUV3_HUMAN	NDUFV3	physical	22658674
NIPS1_HUMAN	NIPSNAP1	physical	22658674
TAB1_HUMAN	TAB1	physical	22658674
ATF4_HUMAN	ATF4	physical	22658674
XRCC6_HUMAN	XRCC6	physical	22658674
CAH5B_HUMAN	CA5B	physical	22658674
DPOLA_HUMAN	POLA1	physical	22658674
RBM10_HUMAN	RBM10	physical	22658674
EBP_HUMAN	EBP	physical	22658674
HDAC6_HUMAN	HDAC6	physical	22658674
SPIN4_HUMAN	SPIN4	physical	22658674
PIN4_HUMAN	PIN4	physical	22658674
MORC4_HUMAN	MORC4	physical	22658674
DHE4_HUMAN	GLUD2	physical	22658674
ENOX2_HUMAN	ENOX2	physical	22658674
MBNL3_HUMAN	MBNL3	physical	22658674
DKC1_HUMAN	DKC1	physical	22658674
FUND2_HUMAN	FUNDC2	physical	22658674
DCTN2_HUMAN	DCTN2	physical	26344197
DDX1_HUMAN	DDX1	physical	26344197
4EBP1_HUMAN	EIF4EBP1	physical	26344197
CH10_HUMAN	HSPE1	physical	26344197
MK12_HUMAN	MAPK12	physical	26344197
PNCB_HUMAN	NAPRT	physical	26344197
SCLY_HUMAN	SCLY	physical	26344197
BRCC3_HUMAN	BRCC3	physical	28514442
ABRX2_HUMAN	FAM175B	physical	24075985
INAR1_HUMAN	IFNAR1	physical	24075985

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
DB00145	Glycine
DB00116	Tetrahydrofolic acid

Regulatory Network of GLYM_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-103; LYS-181; LYS-196;LYS-269; LYS-297; LYS-356; LYS-464; LYS-469 AND LYS-474, AND MASSSPECTROMETRY.	19608861 [Abstract]

show