UniProt ID | PALMD_HUMAN | |
---|---|---|
UniProt AC | Q9NP74 | |
Protein Name | Palmdelphin | |
Gene Name | PALMD | |
Organism | Homo sapiens (Human). | |
Sequence Length | 551 | |
Subcellular Localization | Cytoplasm . Cell projection, dendrite . Cell projection, dendritic spine. | |
Protein Description | ||
Protein Sequence | MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIGVNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAKPTPLPRKRSEASPHENTNHKSPHKNSISLKEQEESLGSPVHHSPFDAQTTGDGTEDPSLTALRMRMAKLGKKVI | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
1 | Acetylation | -------MEEAELVK -------CHHHHHHH | 10.68 | 22814378 | |
56 | Phosphorylation | KWLLDGISSGKEQEE HHHHHHHCCHHHHHH | 38.27 | - | |
81 | Phosphorylation | QIQVLEQSILRLEKE HHHHHHHHHHHHHHH | 17.76 | 20068231 | |
112 | Phosphorylation | AILKKLKSIERTTED HHHHHHHHCCCCHHH | 39.87 | 25159151 | |
125 | Sumoylation | EDIIRSVKVEREERA HHHHHHHHHHHHHHH | 39.36 | 28112733 | |
135 | Phosphorylation | REERAEESIEDIYAN HHHHHHHHHHHHHHC | 23.84 | 21712546 | |
140 | Phosphorylation | EESIEDIYANIPDLP HHHHHHHHHCCCCCC | 13.10 | 25884760 | |
153 | Phosphorylation | LPKSYIPSRLRKEIN CCHHHCCHHHHHHHH | 34.10 | - | |
174 | Phosphorylation | EQNRKALYAMEIKVE HHHHHHHHHHEEEEE | 14.57 | 25159151 | |
179 | Sumoylation | ALYAMEIKVEKDLKT HHHHHEEEEEECCCC | 30.91 | - | |
179 | Sumoylation | ALYAMEIKVEKDLKT HHHHHEEEEEECCCC | 30.91 | 25114211 | |
193 | Phosphorylation | TGESTVLSSIPLPSD CCCCEEEECCCCCCC | 23.14 | 27251275 | |
194 | Phosphorylation | GESTVLSSIPLPSDD CCCEEEECCCCCCCC | 24.86 | 27251275 | |
210 | Phosphorylation | KGTGIKVYDDGQKSV CCCCEEEEECCCCEE | 11.87 | - | |
218 | Phosphorylation | DDGQKSVYAVSSNHS ECCCCEEEEEECCCC | 14.37 | 22817900 | |
221 | Phosphorylation | QKSVYAVSSNHSAAY CCEEEEEECCCCCCC | 19.76 | 30576142 | |
228 | Phosphorylation | SSNHSAAYNGTDGLA ECCCCCCCCCCCCCC | 17.53 | 30576142 | |
231 | Phosphorylation | HSAAYNGTDGLAPVE CCCCCCCCCCCCCHH | 24.21 | 30576142 | |
247 | Phosphorylation | EELLRQASERNSKSP HHHHHHHHHHCCCCC | 28.84 | - | |
251 | Phosphorylation | RQASERNSKSPTEYH HHHHHHCCCCCCCCC | 40.51 | 26055452 | |
253 | Phosphorylation | ASERNSKSPTEYHEP HHHHCCCCCCCCCCC | 36.55 | 21945579 | |
255 | Phosphorylation | ERNSKSPTEYHEPVY HHCCCCCCCCCCCCC | 57.16 | 21945579 | |
257 | Phosphorylation | NSKSPTEYHEPVYAN CCCCCCCCCCCCCCC | 17.60 | 21945579 | |
262 | Phosphorylation | TEYHEPVYANPFYRP CCCCCCCCCCCCCCC | 16.04 | 21945579 | |
267 | Phosphorylation | PVYANPFYRPTTPQR CCCCCCCCCCCCCCC | 19.55 | 21945579 | |
270 | Phosphorylation | ANPFYRPTTPQRETV CCCCCCCCCCCCCCC | 41.95 | 21945579 | |
271 | Phosphorylation | NPFYRPTTPQRETVT CCCCCCCCCCCCCCC | 21.80 | 21945579 | |
276 | Phosphorylation | PTTPQRETVTPGPNF CCCCCCCCCCCCCCH | 31.69 | 25159151 | |
278 | Phosphorylation | TPQRETVTPGPNFQE CCCCCCCCCCCCHHH | 29.92 | 21815630 | |
301 | Phosphorylation | LGIGVNESIHNMGNG CCCCCCHHHHCCCCC | 24.76 | 28555341 | |
321 | Phosphorylation | GNNFNHISPIPPVPH CCCCCCCCCCCCCCC | 14.82 | 22167270 | |
331 | Phosphorylation | PPVPHPRSVIQQAEE CCCCCCHHHHHHHHH | 28.20 | 27251275 | |
339 | Ubiquitination | VIQQAEEKLHTPQKR HHHHHHHHHCCCCHH | 36.75 | - | |
342 | Phosphorylation | QAEEKLHTPQKRLMT HHHHHHCCCCHHCCC | 37.54 | 24732914 | |
354 | Phosphorylation | LMTPWEESNVMQDKD CCCCCHHHCCCCCCC | 24.18 | 22210691 | |
364 | Phosphorylation | MQDKDAPSPKPRLSP CCCCCCCCCCCCCCC | 47.48 | 22167270 | |
370 | Phosphorylation | PSPKPRLSPRETIFG CCCCCCCCCCCCCCC | 24.16 | 25159151 | |
378 | Acetylation | PRETIFGKSEHQNSS CCCCCCCCCCCCCCC | 41.75 | 26051181 | |
379 | Phosphorylation | RETIFGKSEHQNSSP CCCCCCCCCCCCCCC | 40.46 | 22167270 | |
384 | Phosphorylation | GKSEHQNSSPTCQED CCCCCCCCCCCCCCC | 30.99 | 22167270 | |
385 | Phosphorylation | KSEHQNSSPTCQEDE CCCCCCCCCCCCCCH | 31.60 | 25463755 | |
387 | Phosphorylation | EHQNSSPTCQEDEED CCCCCCCCCCCCHHH | 28.86 | 22167270 | |
486 | Phosphorylation | TPLPRKRSEASPHEN CCCCCCCCCCCCCCC | 40.32 | 20068231 | |
489 | Phosphorylation | PRKRSEASPHENTNH CCCCCCCCCCCCCCC | 23.80 | 20068231 | |
494 | Phosphorylation | EASPHENTNHKSPHK CCCCCCCCCCCCCCC | 35.40 | 23403867 | |
498 | Phosphorylation | HENTNHKSPHKNSIS CCCCCCCCCCCCCCC | 25.37 | 26055452 | |
503 | Phosphorylation | HKSPHKNSISLKEQE CCCCCCCCCCHHHHH | 20.54 | 26055452 | |
505 | Phosphorylation | SPHKNSISLKEQEES CCCCCCCCHHHHHHH | 32.96 | 23312004 | |
512 | Phosphorylation | SLKEQEESLGSPVHH CHHHHHHHHCCCCCC | 36.96 | 25159151 | |
515 | Phosphorylation | EQEESLGSPVHHSPF HHHHHHCCCCCCCCC | 29.10 | 25159151 | |
520 | Phosphorylation | LGSPVHHSPFDAQTT HCCCCCCCCCCCCCC | 16.63 | 25159151 | |
526 | Phosphorylation | HSPFDAQTTGDGTED CCCCCCCCCCCCCCC | 34.17 | 30576142 | |
527 | Phosphorylation | SPFDAQTTGDGTEDP CCCCCCCCCCCCCCH | 22.61 | 30576142 | |
531 | Phosphorylation | AQTTGDGTEDPSLTA CCCCCCCCCCHHHHH | 41.79 | 27251275 | |
535 | Phosphorylation | GDGTEDPSLTALRMR CCCCCCHHHHHHHHH | 51.15 | 20068231 | |
537 | Phosphorylation | GTEDPSLTALRMRMA CCCCHHHHHHHHHHH | 28.16 | 20068231 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PALMD_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PALMD_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PALMD_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
Oops, there are no PPI records of PALMD_HUMAN !! |
Kegg Disease | ||||||
---|---|---|---|---|---|---|
There are no disease associations of PTM sites. | ||||||
OMIM Disease | ||||||
There are no disease associations of PTM sites. | ||||||
Kegg Drug | ||||||
There are no disease associations of PTM sites. | ||||||
DrugBank | ||||||
There are no disease associations of PTM sites. |
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Phosphorylation | |
Reference | PubMed |
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-135 AND SER-321, ANDMASS SPECTROMETRY. | |
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-515, AND MASSSPECTROMETRY. | |
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-370, AND MASSSPECTROMETRY. |