dbPTM

RBM10_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RBM10_HUMAN
UniProt AC	P98175
Protein Name	RNA-binding protein 10 {ECO:0000305}
Gene Name	RBM10 {ECO:0000312\|HGNC:HGNC:9896}
Organism	Homo sapiens (Human).
Sequence Length	930
Subcellular Localization	Nucleus . In the extranucleolar nucleoplasm constitutes hundreds of nuclear domains, which dynamically change their structures in a reversible manner. Upon globally reducing RNA polymerase II transcription, the nuclear bodies enlarge and decrease in
Protein Description	May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). May bind to specific miRNA hairpins. [PubMed: 28431233]
Protein Sequence	MEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEDSYEASPGSETQRRRRRRHRHSPTGPPGFPRDGDYRDQDYRTEQGEEEEEEEDEEEEEKASNIVMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIVEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGDPTGAGPEASLEPGADSVSMQAFSRAQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAVLKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MEYERRGGR ------CCCCCCCCC	56.98	23090842
2	Phosphorylation	------MEYERRGGR ------CCCCCCCCC	56.98	23090842
2 (in isoform 5)	Acetylation	-	56.98	21406692
2 (in isoform 5)	Phosphorylation	-	56.98	23663014
4	Phosphorylation	----MEYERRGGRGD ----CCCCCCCCCCC	23.69	23090842
4	Phosphorylation	----MEYERRGGRGD ----CCCCCCCCCCC	23.69	20068231
4 (in isoform 5)	Phosphorylation	-	23.69	28355574
6	Phosphorylation	--MEYERRGGRGDRT --CCCCCCCCCCCCC	39.72	22199227
6	Phosphorylation	--MEYERRGGRGDRT --CCCCCCCCCCCCC	39.72	22199227
6 (in isoform 5)	Phosphorylation	-	39.72	23663014
8	Phosphorylation	MEYERRGGRGDRTGR CCCCCCCCCCCCCCC	28.69	27251275
8 (in isoform 5)	Phosphorylation	-	28.69	27251275
15	Phosphorylation	GRGDRTGRYGATDRS CCCCCCCCCCCCCCC	26.54	27251275
15 (in isoform 5)	Phosphorylation	-	26.54	27251275
16	Phosphorylation	RGDRTGRYGATDRSQ CCCCCCCCCCCCCCC	16.68	22817900
19	Phosphorylation	RTGRYGATDRSQDDG CCCCCCCCCCCCCCC	27.81	29496963
22	Phosphorylation	RYGATDRSQDDGGEN CCCCCCCCCCCCCCC	40.55	25159151
25	Phosphorylation	ATDRSQDDGGENRSR CCCCCCCCCCCCCCC	60.40	-
25	Phosphorylation	ATDRSQDDGGENRSR CCCCCCCCCCCCCCC	60.40	-
25 (in isoform 5)	Phosphorylation	-	60.40	29978859
30	Phosphorylation	QDDGGENRSRDHDYR CCCCCCCCCCCCCCC	28.85	22199227
30	Phosphorylation	QDDGGENRSRDHDYR CCCCCCCCCCCCCCC	28.85	22199227
30 (in isoform 5)	Phosphorylation	-	28.85	21955146
31	Phosphorylation	DDGGENRSRDHDYRD CCCCCCCCCCCCCCC	54.35	22817900
36	Phosphorylation	NRSRDHDYRDMDYRS CCCCCCCCCCCCCCC	12.70	22817900
38	Phosphorylation	SRDHDYRDMDYRSYP CCCCCCCCCCCCCCC	28.24	20068231
38	Phosphorylation	SRDHDYRDMDYRSYP CCCCCCCCCCCCCCC	28.24	24719451
38 (in isoform 5)	Phosphorylation	-	28.24	20068231
39	Phosphorylation	RDHDYRDMDYRSYPR CCCCCCCCCCCCCCH	3.45	27251275
39 (in isoform 5)	Phosphorylation	-	3.45	28348404
40	Phosphorylation	DHDYRDMDYRSYPRE CCCCCCCCCCCCCHH	39.73	21857030
40	Phosphorylation	DHDYRDMDYRSYPRE CCCCCCCCCCCCCHH	39.73	21857030
40 (in isoform 5)	Phosphorylation	-	39.73	20068231
41	Phosphorylation	HDYRDMDYRSYPREY CCCCCCCCCCCCHHH	8.53	22817900
43	Phosphorylation	YRDMDYRSYPREYGS CCCCCCCCCCHHHCC	33.01	23090842
44	Phosphorylation	RDMDYRSYPREYGSQ CCCCCCCCCHHHCCC	9.41	30576142
48	Phosphorylation	YRSYPREYGSQEGKH CCCCCHHHCCCCCCC	24.29	25137130
48 (in isoform 3)	Phosphorylation	-	24.29	28450419
48 (in isoform 4)	Phosphorylation	-	24.29	28450419
50	Phosphorylation	SYPREYGSQEGKHDY CCCHHHCCCCCCCCC	24.94	17525332
50 (in isoform 3)	Phosphorylation	-	24.94	24719451
50 (in isoform 4)	Phosphorylation	-	24.94	24719451
57	Phosphorylation	SQEGKHDYDDSSEEQ CCCCCCCCCCCCCHH	22.75	23401153
57 (in isoform 3)	Phosphorylation	-	22.75	28450419
57 (in isoform 4)	Phosphorylation	-	22.75	28450419
57 (in isoform 5)	Phosphorylation	-	22.75	28176443
58	Phosphorylation	QEGKHDYDDSSEEQS CCCCCCCCCCCCHHC	56.21	24719451
58 (in isoform 5)	Phosphorylation	-	56.21	28176443
60	Phosphorylation	GKHDYDDSSEEQSAE CCCCCCCCCCHHCHH	36.43	17525332
60 (in isoform 3)	Phosphorylation	-	36.43	25849741
60 (in isoform 4)	Phosphorylation	-	36.43	25849741
61	Phosphorylation	KHDYDDSSEEQSAED CCCCCCCCCHHCHHH	52.74	23927012
61 (in isoform 3)	Phosphorylation	-	52.74	23663014
61 (in isoform 4)	Phosphorylation	-	52.74	23663014
63 (in isoform 5)	Phosphorylation	-	52.35	28102081
65	Phosphorylation	DDSSEEQSAEDSYEA CCCCCHHCHHHHCCC	36.58	23927012
65 (in isoform 3)	Phosphorylation	-	36.58	30108239
65 (in isoform 4)	Phosphorylation	-	36.58	30108239
68	Phosphorylation	SEEQSAEDSYEASPG CCHHCHHHHCCCCCC	57.12	-
68	Phosphorylation	SEEQSAEDSYEASPG CCHHCHHHHCCCCCC	57.12	-
68 (in isoform 5)	Phosphorylation	-	57.12	-
69	Phosphorylation	EEQSAEDSYEASPGS CHHCHHHHCCCCCCC	19.17	23927012
70	Phosphorylation	EQSAEDSYEASPGSE HHCHHHHCCCCCCCH	28.03	23927012
73	Phosphorylation	AEDSYEASPGSETQR HHHHCCCCCCCHHHH	20.18	23927012
76	Phosphorylation	SYEASPGSETQRRRR HCCCCCCCHHHHHHH	40.63	23927012
78	Phosphorylation	EASPGSETQRRRRRR CCCCCCHHHHHHHHH	29.13	30576142
87	Phosphorylation	RRRRRRHRHSPTGPP HHHHHHHCCCCCCCC	30.12	24719451
89	Phosphorylation	RRRRHRHSPTGPPGF HHHHHCCCCCCCCCC	24.90	29255136
91	Phosphorylation	RRHRHSPTGPPGFPR HHHCCCCCCCCCCCC	66.39	22167270
102	Phosphorylation	GFPRDGDYRDQDYRT CCCCCCCCCCCCCCC	22.94	27642862
107	Phosphorylation	GDYRDQDYRTEQGEE CCCCCCCCCCCCCCH	17.50	30576142
109	Phosphorylation	YRDQDYRTEQGEEEE CCCCCCCCCCCCHHH	26.82	30576142
125	Phosphorylation	EEDEEEEEKASNIVM HCCHHHHHHHHHHHH	58.14	27251275
126	Phosphorylation	EDEEEEEKASNIVML CCHHHHHHHHHHHHE	61.47	24719451
126	Sumoylation	EDEEEEEKASNIVML CCHHHHHHHHHHHHE	61.47	-
128	Phosphorylation	EEEEEKASNIVMLRM HHHHHHHHHHHHEEE	37.85	30576142
130	Phosphorylation	EEEKASNIVMLRMLP HHHHHHHHHHEEECC	1.46	27251275
134	Methylation	ASNIVMLRMLPQAAT HHHHHHEEECCCCCC	13.39	115490479
135	Phosphorylation	SNIVMLRMLPQAATE HHHHHEEECCCCCCC	5.88	27251275
135	Sulfoxidation	SNIVMLRMLPQAATE HHHHHEEECCCCCCC	5.88	21406390
138	Phosphorylation	VMLRMLPQAATEDDI HHEEECCCCCCCCHH	39.40	27251275
141	Phosphorylation	RMLPQAATEDDIRGQ EECCCCCCCCHHHHH	42.85	30576142
146	Methylation	AATEDDIRGQLQSHG CCCCCHHHHHHHHCC	33.52	115490483
154	Phosphorylation	GQLQSHGVQAREVRL HHHHHCCCCHHEEEE	3.17	24719451
166	Phosphorylation	VRLMRNKSSGQSRGF EEEECCCCCCCCCCE	43.16	-
171	Methylation	NKSSGQSRGFAFVEF CCCCCCCCCEEEEEE	36.04	115490491
194	Phosphorylation	WMEANQHSLNILGQK HHHHHHHHHHHHCCE	17.22	25159151
203	Phosphorylation	NILGQKVSMHYSDPK HHHCCEEECCCCCCC	13.58	25599653
206	Phosphorylation	GQKVSMHYSDPKPKI CCEEECCCCCCCCCC	13.21	30631047
207	Phosphorylation	QKVSMHYSDPKPKIN CEEECCCCCCCCCCC	32.53	25159151
228	Acetylation	KCGVQNFKRREKCFK HHCCCCHHHHHHHHH	59.08	25953088
246	Sumoylation	PKSEAEQKLPLGTRL CHHHHHHHCCCCCCC	43.51	-
246	Sumoylation	PKSEAEQKLPLGTRL CHHHHHHHCCCCCCC	43.51	-
246	Ubiquitination	PKSEAEQKLPLGTRL CHHHHHHHCCCCCCC	43.51	-
257	Phosphorylation	GTRLDQQTLPLGGRE CCCCCCCCCCCCCCC	25.39	28555341
266	Phosphorylation	PLGGRELSQGLLPLP CCCCCCHHCCCCCCC	19.90	27251275
276	Phosphorylation	LLPLPQPYQAQGVLA CCCCCCCCCHHHHHH	15.95	-
288	Phosphorylation	VLASQALSQGSEPSS HHHHHHHHCCCCCCC	35.20	17525332
312	Phosphorylation	RNLNPHSTMDSILGA ECCCCCCCHHHHHHH	23.20	-
331	Phosphorylation	AVLSSSNVRVIKDKQ HHHCCCCEEEECCCC	5.81	27251275
337	2-Hydroxyisobutyrylation	NVRVIKDKQTQLNRG CEEEECCCCCHHHCC	50.68	-
382	Acetylation	KTINVEFAKGSKRDM EEEEEEECCCCHHHC	11.20	19608861
383	Acetylation	TINVEFAKGSKRDMA EEEEEECCCCHHHCC	69.87	19608861
383	Malonylation	TINVEFAKGSKRDMA EEEEEECCCCHHHCC	69.87	26320211
383	Ubiquitination	TINVEFAKGSKRDMA EEEEEECCCCHHHCC	69.87	19608861
435	Phosphorylation	SEEPPVDYSYYQQDE CCCCCCCCCEEECCC	9.98	-
447	Phosphorylation	QDEGYGNSQGTESSL CCCCCCCCCCCCCCH	26.14	-
469	Phosphorylation	GTKGPGITGTKGDPT CCCCCCCCCCCCCCC	44.72	-
471	Phosphorylation	KGPGITGTKGDPTGA CCCCCCCCCCCCCCC	24.17	-
472	Acetylation	GPGITGTKGDPTGAG CCCCCCCCCCCCCCC	63.76	26051181
476	Phosphorylation	TGTKGDPTGAGPEAS CCCCCCCCCCCCCCC	44.39	-
483	Phosphorylation	TGAGPEASLEPGADS CCCCCCCCCCCCCCC	31.44	28555341
490	Phosphorylation	SLEPGADSVSMQAFS CCCCCCCCCCHHHHH	18.63	28555341
492	Phosphorylation	EPGADSVSMQAFSRA CCCCCCCCHHHHHHC	14.77	28555341
497	Phosphorylation	SVSMQAFSRAQPGAA CCCHHHHHHCCCCCC	29.71	-
515	Phosphorylation	YQQSAEASSSQGTAA CCCCCHHHCCCCCCC	23.25	28348404
516	Phosphorylation	QQSAEASSSQGTAAN CCCCHHHCCCCCCCC	33.46	27251275
517	Phosphorylation	QSAEASSSQGTAANS CCCHHHCCCCCCCCC	30.08	17525332
520	Phosphorylation	EASSSQGTAANSQSY HHHCCCCCCCCCCCE	18.24	27251275
524	Phosphorylation	SQGTAANSQSYTIMS CCCCCCCCCCEEEEC	18.77	22199227
526	Phosphorylation	GTAANSQSYTIMSPA CCCCCCCCEEEECHH	24.86	30576142
527	Phosphorylation	TAANSQSYTIMSPAV CCCCCCCEEEECHHH	7.83	28634298
528	Phosphorylation	AANSQSYTIMSPAVL CCCCCCEEEECHHHH	18.56	22199227
531	Phosphorylation	SQSYTIMSPAVLKSE CCCEEEECHHHHHHH	13.07	29496963
536	Sumoylation	IMSPAVLKSELQSPT EECHHHHHHHHCCCC	34.97	-
537	Phosphorylation	MSPAVLKSELQSPTH ECHHHHHHHHCCCCC	39.10	26074081
541	Phosphorylation	VLKSELQSPTHPSSA HHHHHHCCCCCCHHC	44.37	26074081
543	Phosphorylation	KSELQSPTHPSSALP HHHHCCCCCCHHCCC	52.22	26074081
546	Phosphorylation	LQSPTHPSSALPPAT HCCCCCCHHCCCCCC	22.19	26074081
547	Phosphorylation	QSPTHPSSALPPATS CCCCCCHHCCCCCCC	37.97	26074081
553	Phosphorylation	SSALPPATSPTAQES HHCCCCCCCCCCCHH	40.80	26074081
554	Phosphorylation	SALPPATSPTAQESY HCCCCCCCCCCCHHH	23.51	26074081
556	Phosphorylation	LPPATSPTAQESYSQ CCCCCCCCCCHHHCC	40.51	25137130
560	Phosphorylation	TSPTAQESYSQYPVP CCCCCCHHHCCCCCC	20.29	26074081
561	Phosphorylation	SPTAQESYSQYPVPD CCCCCHHHCCCCCCC	10.07	26074081
596	Phosphorylation	YYDPNSQYYYNAQSQ EECCCCCEEEEEECC	14.03	27251275
622	Phosphorylation	YVPALEQSADGHKET CCCCEECCCCCCCCC	20.96	25159151
629	Phosphorylation	SADGHKETGAPSKEG CCCCCCCCCCCCCCC	43.37	28555341
633	Phosphorylation	HKETGAPSKEGKEKK CCCCCCCCCCCHHHH	42.69	-
647	Phosphorylation	KEKHKTKTAQQIAKD HHHHHHHHHHHHHHH	34.62	21601212
653	Acetylation	KTAQQIAKDMERWAR HHHHHHHHHHHHHHH	60.27	22990431
661	Phosphorylation	DMERWARSLNKQKEN HHHHHHHHHHHHHHH	28.66	18669648
672	Phosphorylation	QKENFKNSFQPISSL HHHHHHHCCCCHHHC	26.33	21406692
677	Phosphorylation	KNSFQPISSLRDDER HHCCCCHHHCCCHHH	29.97	28258704
678	Phosphorylation	NSFQPISSLRDDERR HCCCCHHHCCCHHHH	28.30	25954137
687	Phosphorylation	RDDERRESATADAGY CCHHHHHHHHHHHHH	29.16	20873877
689	Phosphorylation	DERRESATADAGYAI HHHHHHHHHHHHHHH	34.06	29978859
694	Phosphorylation	SATADAGYAILEKKG HHHHHHHHHHHHHHC	7.68	28796482
709	Phosphorylation	ALAERQHTSMDLPKL HHHHCCCCCCCHHHH	19.87	28450419
710	Phosphorylation	LAERQHTSMDLPKLA HHHCCCCCCCHHHHC	14.26	28450419
718	Phosphorylation	MDLPKLASDDRPSPP CCHHHHCCCCCCCCC	50.94	29255136
722	Phosphorylation	KLASDDRPSPPRGLV HHCCCCCCCCCCCEE	59.17	17287340
723	O-linked_Glycosylation	LASDDRPSPPRGLVA HCCCCCCCCCCCEEE	48.72	30379171
723	Phosphorylation	LASDDRPSPPRGLVA HCCCCCCCCCCCEEE	48.72	29255136
732	Phosphorylation	PRGLVAAYSGESDSE CCCEEEEECCCCCCH	13.89	29255136
733	Phosphorylation	RGLVAAYSGESDSEE CCEEEEECCCCCCHH	31.21	29255136
735	Phosphorylation	LVAAYSGESDSEEEQ EEEEECCCCCCHHHH	45.49	15302935
736	Phosphorylation	VAAYSGESDSEEEQE EEEECCCCCCHHHHH	50.38	29255136
737	Phosphorylation	AAYSGESDSEEEQER EEECCCCCCHHHHHH	56.62	15302935
738	Phosphorylation	AYSGESDSEEEQERG EECCCCCCHHHHHHC	57.07	29255136
754	Phosphorylation	PEREEKLTDWQKLAC CHHHHHHCHHHHHHH	46.38	24719451
758	Acetylation	EKLTDWQKLACLLCR HHHCHHHHHHHHHHH	33.52	26051181
771	Acetylation	CRRQFPSKEALIRHQ HHCCCCCHHHHHHHH	47.44	26051181
774	Phosphorylation	QFPSKEALIRHQQLS CCCCHHHHHHHHHHH	3.57	24719451
781	Phosphorylation	LIRHQQLSGLHKQNL HHHHHHHHHHHHHCH	34.66	20068231
788	Phosphorylation	SGLHKQNLEIHRRAH HHHHHHCHHHHHHHC	6.40	24719451
797	Phosphorylation	IHRRAHLSENELEAL HHHHHCCCHHHHHHH	28.63	29255136
798	Phosphorylation	HRRAHLSENELEALE HHHHCCCHHHHHHHH	62.17	24719451
801	Phosphorylation	AHLSENELEALEKND HCCCHHHHHHHHHCC	7.61	24719451
803	Phosphorylation	LSENELEALEKNDME CCHHHHHHHHHCCHH	33.38	24719451
825	Phosphorylation	AAERREKYGIPEPPE HHHHHHHHCCCCCCC	18.61	17192257
838	Phosphorylation	PEPKRRKYGGISTAS CCCCCCCCCCCCCCE	20.83	20873877
842	Phosphorylation	RRKYGGISTASVDFE CCCCCCCCCCEECCC	22.61	20873877
843	Phosphorylation	RKYGGISTASVDFEQ CCCCCCCCCEECCCC	22.49	20873877
845	Phosphorylation	YGGISTASVDFEQPT CCCCCCCEECCCCCC	23.47	21712546
852	Phosphorylation	SVDFEQPTRDGLGSD EECCCCCCCCCCCCC	40.88	26074081
858	Phosphorylation	PTRDGLGSDNIGSRM CCCCCCCCCCHHHHH	32.31	20873877
862	Phosphorylation	GLGSDNIGSRMLQAM CCCCCCHHHHHHHHH	18.56	24719451
872	Acetylation	MLQAMGWKEGSGLGR HHHHHCCCCCCCCCC	46.60	26051181
881	Sumoylation	GSGLGRKKQGIVTPI CCCCCCCCCCEECCC	53.01	-
881	Methylation	GSGLGRKKQGIVTPI CCCCCCCCCCEECCC	53.01	24129315
881	Sumoylation	GSGLGRKKQGIVTPI CCCCCCCCCCEECCC	53.01	-
881	Ubiquitination	GSGLGRKKQGIVTPI CCCCCCCCCCEECCC	53.01	-
886	Phosphorylation	RKKQGIVTPIEAQTR CCCCCEECCCEEECC	19.34	20068231
892	Phosphorylation	VTPIEAQTRVRGSGL ECCCEEECCCCCCCC	37.87	20068231
895	Methylation	IEAQTRVRGSGLGAR CEEECCCCCCCCCCC	30.21	54558535
897	Phosphorylation	AQTRVRGSGLGARGS EECCCCCCCCCCCCC	21.93	28555341
902	Methylation	RGSGLGARGSSYGVT CCCCCCCCCCCCCCC	43.67	24129315
904	Phosphorylation	SGLGARGSSYGVTST CCCCCCCCCCCCCCC	18.16	23401153
905	Phosphorylation	GLGARGSSYGVTSTE CCCCCCCCCCCCCCH	28.82	25159151
906	Phosphorylation	LGARGSSYGVTSTES CCCCCCCCCCCCCHH	19.81	28555341
908	Phosphorylation	ARGSSYGVTSTESYK CCCCCCCCCCCHHHH	2.65	27251275
909	Phosphorylation	RGSSYGVTSTESYKE CCCCCCCCCCHHHHH	26.10	26714015
910	Phosphorylation	GSSYGVTSTESYKET CCCCCCCCCHHHHHH	27.98	24719451
911	O-linked_Glycosylation	SSYGVTSTESYKETL CCCCCCCCHHHHHHH	21.42	30379171
911	Phosphorylation	SSYGVTSTESYKETL CCCCCCCCHHHHHHH	21.42	28555341
913	Phosphorylation	YGVTSTESYKETLHK CCCCCCHHHHHHHHH	41.41	29507054
915	Acetylation	VTSTESYKETLHKTM CCCCHHHHHHHHHHH	54.20	26051181
917	Phosphorylation	STESYKETLHKTMVT CCHHHHHHHHHHHHH	29.97	28152594
920	Acetylation	SYKETLHKTMVTRFN HHHHHHHHHHHHHHH	41.24	25953088
921	Phosphorylation	YKETLHKTMVTRFNE HHHHHHHHHHHHHHH	13.21	28152594
924	Phosphorylation	TLHKTMVTRFNEAQ- HHHHHHHHHHHHCC-	20.79	28152594
951	Phosphorylation	---------------------------- ----------------------------		27251275
969	Phosphorylation	---------------------------------------------- ----------------------------------------------		27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RBM10_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RBM10_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RBM10_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PTBP2_HUMAN	PTBP2	physical	16189514
F124A_HUMAN	FAM124A	physical	16189514
RU1C_HUMAN	SNRPC	physical	22365833
SF3A1_HUMAN	SF3A1	physical	22365833
SF3B4_HUMAN	SF3B4	physical	22365833
DHX15_HUMAN	DHX15	physical	22365833
U2AF2_HUMAN	U2AF2	physical	22365833
U2AF1_HUMAN	U2AF1	physical	22365833
SR140_HUMAN	U2SURP	physical	22365833
CCAR1_HUMAN	CCAR1	physical	22365833
RBM10_HUMAN	RBM10	physical	22365833
SF01_HUMAN	SF1	physical	22365833
SUGP1_HUMAN	SUGP1	physical	22365833
SRSF6_HUMAN	SRSF6	physical	22365833
PRP19_HUMAN	PRPF19	physical	22365833
PRCC_HUMAN	PRCC	physical	22365833
RED_HUMAN	IK	physical	22365833
PRP16_HUMAN	DHX38	physical	22365833
DDX5_HUMAN	DDX5	physical	22365833
HNRPK_HUMAN	HNRNPK	physical	22365833
RBM4_HUMAN	RBM4	physical	22365833
HNRH2_HUMAN	HNRNPH2	physical	22365833
GPKOW_HUMAN	GPKOW	physical	22365833
PTBP1_HUMAN	PTBP1	physical	22365833
PTBP2_HUMAN	PTBP2	physical	22365833
TB22B_HUMAN	TBC1D22B	physical	25416956

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
311900	TARP syndrome (TARPS)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RBM10_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-383, AND MASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-60; SER-61; SER-65;SER-723; SER-733; SER-736; SER-738 AND SER-797, AND MASS SPECTROMETRY.	18669648 [Abstract]
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