F124A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F124A_HUMAN
• UniProt AC: Q86V42
• Protein Name: Protein FAM124A
• Gene Name: FAM124A
• Organism: Homo sapiens (Human).
• Sequence Length: 546
• Protein Sequence: MDPKAGGGGEEDDCVDSGAETGGSDYSHLSSTSSELSVEEAQDPFLVSIHIIADPGESQPLQEAIDNVLAWIHPDLPLFRVSERRASRRRRKPPKGAQPALAVVLFLQEEYGEEQILQLHRTLQQPPWRHHHTEQVHGRFLPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTVYCRYDNYADSLRFYQLILRRSPSQKKADFCIFPIFSNLDVDIQFSLKRLPCDQCPVPTDSSVLEFRVRDIGELVPLLPNPCSPISEGRWQTEDHDGNKILLQAQRVHKKFPKPGRVHHASEKKRHSTPLPSTAVPSHTPGSSQQSPLNSPHPGPIRTGLPPGHQQEFAGRANSTPNPPWSFQRSKSLFCLPTGGPSLASSAEPQWFSNTGAPGHRASEWRHGHLLSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCSTVETPLPSERCSSHWAAHKDSREGPLPTVSRVTTEASWASLPFFTKRSSSSSATARAAPPAPSTSTLTDSSPQLPCDTPKVKQTDGDMPPPPGSAGPGDNDMEEFYI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
173	Methylation	HYGKEIVRFTVYCRY CCCCCEEEEEEEECC	27.46	-
179	Methylation	VRFTVYCRYDNYADS EEEEEEECCCCHHHH	24.93	-
183	Phosphorylation	VYCRYDNYADSLRFY EEECCCCHHHHHHHH	14.64	26503514
190	Phosphorylation	YADSLRFYQLILRRS HHHHHHHHHHHHHCC	8.93	26503514
197	Phosphorylation	YQLILRRSPSQKKAD HHHHHHCCCCCCCCC	23.59	-
199	Phosphorylation	LILRRSPSQKKADFC HHHHCCCCCCCCCEE	56.74	-
212	Phosphorylation	FCIFPIFSNLDVDIQ EEEEECCCCCCEEEC	36.88	-
221	Phosphorylation	LDVDIQFSLKRLPCD CCEEECEECCCCCCC	19.33	-
312	Phosphorylation	LPSTAVPSHTPGSSQ CCCCCCCCCCCCCCC	33.13	27732954
314	Phosphorylation	STAVPSHTPGSSQQS CCCCCCCCCCCCCCC	33.41	27732954
317	Phosphorylation	VPSHTPGSSQQSPLN CCCCCCCCCCCCCCC	26.61	28152594
318	Phosphorylation	PSHTPGSSQQSPLNS CCCCCCCCCCCCCCC	37.85	28152594
321	Phosphorylation	TPGSSQQSPLNSPHP CCCCCCCCCCCCCCC	24.58	28152594
325	Phosphorylation	SQQSPLNSPHPGPIR CCCCCCCCCCCCCCC	32.06	28152594
350	Phosphorylation	FAGRANSTPNPPWSF CCCCCCCCCCCCCCC	27.22	28555341
354	Phosphorylation	ANSTPNPPWSFQRSK CCCCCCCCCCCCCCC	46.08	24719451
360	Phosphorylation	PPWSFQRSKSLFCLP CCCCCCCCCCEEEEC	18.80	24719451
362	Phosphorylation	WSFQRSKSLFCLPTG CCCCCCCCEEEECCC	28.11	27251275
396	Phosphorylation	GHRASEWRHGHLLSI CCCCCCCCCCCEEEH	23.12	24719451
398	Phosphorylation	RASEWRHGHLLSIDD CCCCCCCCCEEEHHH	12.45	27251275
402	Phosphorylation	WRHGHLLSIDDLEGA CCCCCEEEHHHCCCC	30.26	27732954
429	Phosphorylation	SSDLSVVSAYSAPSR CCCCEEEECCCCCCC	21.23	24719451
432	Phosphorylation	LSVVSAYSAPSRFCS CEEEECCCCCCCCCC	33.16	19664994
447	Phosphorylation	TVETPLPSERCSSHW CCCCCCCCHHCHHCH	45.41	24719451
465	Phosphorylation	KDSREGPLPTVSRVT CCCCCCCCCCEEEEE	9.03	24719451
467	Phosphorylation	SREGPLPTVSRVTTE CCCCCCCCEEEEEEC	38.50	22985185
473	O-linked_Glycosylation	PTVSRVTTEASWASL CCEEEEEECCHHHCC	27.05	28657654
487	Phosphorylation	LPFFTKRSSSSSATA CCEEECCCCCCCCCC	35.81	24732914
493	Phosphorylation	RSSSSSATARAAPPA CCCCCCCCCCCCCCC	20.72	24732914

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F124A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F124A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F124A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
STAC3_HUMAN	STAC3	physical	25416956
IN80E_HUMAN	INO80E	physical	25416956
IHO1_HUMAN	CCDC36	physical	25416956
BEND7_HUMAN	BEND7	physical	21516116
CCD33_HUMAN	CCDC33	physical	21516116

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.