BEND7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BEND7_HUMAN
• UniProt AC: Q8N7W2
• Protein Name: BEN domain-containing protein 7
• Gene Name: BEND7
• Organism: Homo sapiens (Human).
• Sequence Length: 519
• Protein Sequence: MEFSERKRSRKSQSFKLVSRDYHHEVYKIPEFSNDVNGEAKETQPIFLGDESMEIKKQITGMRRLLNDSTGRIYQRVGKEGEKLKEEPQDLDLVWPPRLNSSAEAPQSLHPSSRGVWNELPPQSGQFSGQYGTRSRTFQSQPHPTTSSNGELPVVNSSAGSNCCTCNCQSTLQAILQELKTMRKLMQIQAVGTQNRQQPPISLICSQRTAVSRKRNKKKKVPPKTVEPLTVKQKPSGSEMEKKSVVASELSALQAAEHTSPEESRVLGFGIVLESPSSDPEVQLAEGFDVFMPKSQLDSILSNYTRSGSLLFRKLVCAFFDDKTLANSLPNGKRKRGLNDNRKGLDQNIVGAIKVFTEKYCTANHVDKLPGPRDWVQILQDQIKLARRRLKRGSEIADSDERLDGIALPPTGACGGPCTVLPGGSAAVTLVLQSSPQTMSQEKGQMAEPWEEQHLVLLNNLTRDRAETGALSQTSQDFKHHSFLITQVSATLHHQRGIRNFPTPGSAKSLTLHISCLSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	EFSERKRSRKSQSFK CHHHHHHHHHCCCEE	47.28	29978859
12	Phosphorylation	ERKRSRKSQSFKLVS HHHHHHHCCCEEEEE	29.91	29978859
14	Phosphorylation	KRSRKSQSFKLVSRD HHHHHCCCEEEEECC	31.29	29978859
16	Sumoylation	SRKSQSFKLVSRDYH HHHCCCEEEEECCCC	53.91	28112733
56	Sumoylation	GDESMEIKKQITGMR CCCCHHHHHHHHHHH	25.89	28112733
56	Phosphorylation	GDESMEIKKQITGMR CCCCHHHHHHHHHHH	25.89	20068231
60	Phosphorylation	MEIKKQITGMRRLLN HHHHHHHHHHHHHHC	23.56	22210691
85	Sumoylation	GKEGEKLKEEPQDLD CCCCHHHCCCCCCCC	71.72	28112733
101	Phosphorylation	VWPPRLNSSAEAPQS CCCCCCCCCCCCCHH	35.20	20068231
102	Phosphorylation	WPPRLNSSAEAPQSL CCCCCCCCCCCCHHC	29.11	20068231
108	Phosphorylation	SSAEAPQSLHPSSRG CCCCCCHHCCCCCCC	27.82	20068231
112	Phosphorylation	APQSLHPSSRGVWNE CCHHCCCCCCCCCCC	23.17	20068231
113	Phosphorylation	PQSLHPSSRGVWNEL CHHCCCCCCCCCCCC	37.19	20068231
181	Phosphorylation	AILQELKTMRKLMQI HHHHHHHHHHHHHHH	34.53	-
193	Phosphorylation	MQIQAVGTQNRQQPP HHHHHHCCCCCCCCC	18.97	22964224
199	Phosphorylation	GTQNRQQPPISLICS CCCCCCCCCEEEEEC	21.61	27251275
207	Phosphorylation	PISLICSQRTAVSRK CEEEEECCCCHHHHH	42.19	24719451
238	Phosphorylation	VKQKPSGSEMEKKSV EECCCCCCHHHHHHH	37.80	-
242	Acetylation	PSGSEMEKKSVVASE CCCCHHHHHHHHHHH	49.38	30587185
243	Sumoylation	SGSEMEKKSVVASEL CCCHHHHHHHHHHHH	34.87	28112733
244	Phosphorylation	GSEMEKKSVVASELS CCHHHHHHHHHHHHH	32.65	23312004
248	Phosphorylation	EKKSVVASELSALQA HHHHHHHHHHHHHHH	27.71	23312004
250	Phosphorylation	KSVVASELSALQAAE HHHHHHHHHHHHHHC	3.17	18669648
251	Phosphorylation	SVVASELSALQAAEH HHHHHHHHHHHHHCC	23.92	23312004
255	Phosphorylation	SELSALQAAEHTSPE HHHHHHHHHCCCCHH	18.70	18669648
259	Phosphorylation	ALQAAEHTSPEESRV HHHHHCCCCHHHHCE	37.17	30266825
260	Phosphorylation	LQAAEHTSPEESRVL HHHHCCCCHHHHCEE	32.02	30266825
264	Phosphorylation	EHTSPEESRVLGFGI CCCCHHHHCEEEEEE	26.48	30266825
272	Phosphorylation	RVLGFGIVLESPSSD CEEEEEEEEECCCCC	5.06	20068231
276	Phosphorylation	FGIVLESPSSDPEVQ EEEEEECCCCCCCCH	28.60	20068231
302	Phosphorylation	SQLDSILSNYTRSGS HHHHHHHHCCCCCCC	26.56	18669648
307	Phosphorylation	ILSNYTRSGSLLFRK HHHCCCCCCCHHHHH	25.57	18669648
324	Phosphorylation	CAFFDDKTLANSLPN HHHCCCHHHHHHCCC	37.79	20068231
328	Phosphorylation	DDKTLANSLPNGKRK CCHHHHHHCCCCCCC	39.33	28112733
431	Phosphorylation	GSAAVTLVLQSSPQT CCEEEEEEEECCCCC	3.14	20068231
435	Phosphorylation	VTLVLQSSPQTMSQE EEEEEECCCCCCCCC	14.20	20068231
472	Phosphorylation	RAETGALSQTSQDFK HHHHCCCCCCCHHHH	30.77	29116813
474	Phosphorylation	ETGALSQTSQDFKHH HHCCCCCCCHHHHHH	25.61	29116813
482	Phosphorylation	SQDFKHHSFLITQVS CHHHHHHCCEEEHHH	22.82	20068231
486	Phosphorylation	KHHSFLITQVSATLH HHHCCEEEHHHHHHH	25.68	20068231
489	Phosphorylation	SFLITQVSATLHHQR CCEEEHHHHHHHHCC	13.01	20068231
491	Phosphorylation	LITQVSATLHHQRGI EEEHHHHHHHHCCCC	21.08	20068231

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BEND7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BEND7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BEND7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PPR37_HUMAN	PPP1R37	physical	16189514
BEND7_HUMAN	BEND7	physical	25416956
F133A_HUMAN	FAM133A	physical	25416956
TRI27_HUMAN	TRIM27	physical	26186194
C1QBP_HUMAN	C1QBP	physical	26186194
LRP4_HUMAN	LRP4	physical	26186194
NP1L3_HUMAN	NAP1L3	physical	21516116
LYAR_HUMAN	LYAR	physical	21516116
EAF2_HUMAN	EAF2	physical	21516116
EIF1A_HUMAN	EIF1AD	physical	21516116
EAF1_HUMAN	EAF1	physical	21516116
LRP4_HUMAN	LRP4	physical	28514442
C1QBP_HUMAN	C1QBP	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.