NP1L3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NP1L3_HUMAN
• UniProt AC: Q99457
• Protein Name: Nucleosome assembly protein 1-like 3
• Gene Name: NAP1L3
• Organism: Homo sapiens (Human).
• Sequence Length: 506
• Subcellular Localization: Nucleus.
• Protein Sequence: MAEADFKMVSEPVAHGVAEEEMASSTSDSGEESDSSSSSSSTSDSSSSSSTSGSSSGSGSSSSSSGSTSSRSRLYRKKRVPEPSRRARRAPLGTNFVDRLPQAVRNRVQALRNIQDECDKVDTLFLKAIHDLERKYAELNKPLYDRRFQIINAEYEPTEEECEWNSEDEEFSSDEEVQDNTPSEMPPLEGEEEENPKENPEVKAEEKEVPKEIPEVKDEEKEVPKEIPEVKAEEKADSKDCMEATPEVKEDPKEVPQVKADDKEQPKATEAKARAAVRETHKRVPEERLQDSVDLKRARKGKPKREDPKGIPDYWLIVLKNVDKLGPMIQKYDEPILKFLSDVSLKFSKPGQPVSYTFEFHFLPNPYFRNEVLVKTYIIKAKPDHNDPFFSWGWEIEDCKGCKIDWRRGKDVTVTTTQSRTTATGEIEIQPRVVPNASFFNFFSPPEIPMIGKLEPREDAILDEDFEIGQILHDNVILKSIYYYTGEVNGTYYQFGKHYGNKKYRK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
39	Phosphorylation	ESDSSSSSSSTSDSS CCCCCCCCCCCCCCC	30.20	-
41	Phosphorylation	DSSSSSSSTSDSSSS CCCCCCCCCCCCCCC	33.60	-
42	Phosphorylation	SSSSSSSTSDSSSSS CCCCCCCCCCCCCCC	38.20	-
45	Phosphorylation	SSSSTSDSSSSSSTS CCCCCCCCCCCCCCC	31.70	-
46	Phosphorylation	SSSTSDSSSSSSTSG CCCCCCCCCCCCCCC	38.95	-
47	Phosphorylation	SSTSDSSSSSSTSGS CCCCCCCCCCCCCCC	37.89	-
50	Phosphorylation	SDSSSSSSTSGSSSG CCCCCCCCCCCCCCC	28.65	-
52	Phosphorylation	SSSSSSTSGSSSGSG CCCCCCCCCCCCCCC	38.33	-
54	Phosphorylation	SSSSTSGSSSGSGSS CCCCCCCCCCCCCCC	22.54	-
55	Phosphorylation	SSSTSGSSSGSGSSS CCCCCCCCCCCCCCC	42.09	-
61	Phosphorylation	SSSGSGSSSSSSGST CCCCCCCCCCCCCCC	37.45	-
64	Phosphorylation	GSGSSSSSSGSTSSR CCCCCCCCCCCCCCC	40.44	-
68	Phosphorylation	SSSSSGSTSSRSRLY CCCCCCCCCCCHHHH	33.96	-
70	Phosphorylation	SSSGSTSSRSRLYRK CCCCCCCCCHHHHHC	34.07	-
144	Phosphorylation	AELNKPLYDRRFQII HHHCCCHHHHCEEEE	18.87	30576142
245	Phosphorylation	SKDCMEATPEVKEDP CCCHHHHCCCCCCCC	13.48	-
296	Ubiquitination	LQDSVDLKRARKGKP HHHHHHHHHHHCCCC	39.28	-
331	Ubiquitination	KLGPMIQKYDEPILK HHHHHHHHCCHHHHH	43.68	-
413	Phosphorylation	WRRGKDVTVTTTQSR EECCCCEEEEEECCC	23.44	23403867
415	Phosphorylation	RGKDVTVTTTQSRTT CCCCEEEEEECCCCC	18.11	23403867
416	Phosphorylation	GKDVTVTTTQSRTTA CCCEEEEEECCCCCC	20.64	23403867
417	Phosphorylation	KDVTVTTTQSRTTAT CCEEEEEECCCCCCC	18.38	23403867

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NP1L3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NP1L3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NP1L3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TSYL4_HUMAN	TSPYL4	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.