TSYL4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TSYL4_HUMAN
• UniProt AC: Q9UJ04
• Protein Name: Testis-specific Y-encoded-like protein 4
• Gene Name: TSPYL4
• Organism: Homo sapiens (Human).
• Sequence Length: 414
• Protein Sequence: MSGLDGGNKLPLAQTGGLAAPDHASGDPDRDQCQGLREETEATQVMANTGGGSLETVAEGGASQDPVDCGPALRVPVAGSRGGAATKAGQEDAPPSTKGLEAASAAEAADSSQKNGCQLGEPRGPAGQKALEACGAGGLGSQMIPGKKAKEVTTKKRAISAAVEKEGEAGAAMEEKKVVQKEKKVAGGVKEETRPRAPKINNCMDSLEAIDQELSNVNAQADRAFLQLERKFGRMRRLHMQRRSFIIQNIPGFWVTAFRNHPQLSPMISGQDEDMLRYMINLEVEELKHPRAGCKFKFIFQGNPYFRNEGLVKEYERRSSGRVVSLSTPIRWHRGQDPQAHIHRNREGNTIPSFFNWFSDHSLLEFDRIAEIIKGELWPNPLQYYLMGEGPRRGIRGPPRQPVESARSFRFQSG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	Phosphorylation	CQGLREETEATQVMA HHHHHHHHHHHHHHH	26.60	22210691
43	Phosphorylation	LREETEATQVMANTG HHHHHHHHHHHHCCC	18.57	22210691
49	Phosphorylation	ATQVMANTGGGSLET HHHHHHCCCCCCHHH	27.89	24275569
56	Phosphorylation	TGGGSLETVAEGGAS CCCCCHHHHHCCCCC	30.24	24275569
63	Phosphorylation	TVAEGGASQDPVDCG HHHCCCCCCCCCCCC	38.09	22210691
96	Phosphorylation	GQEDAPPSTKGLEAA CCCCCCCCCHHHHHH	41.51	22468782
199	Ubiquitination	ETRPRAPKINNCMDS CCCCCCCCCCCHHHH	58.02	-
206	Phosphorylation	KINNCMDSLEAIDQE CCCCHHHHHHHHHHH	10.96	27499020
244	Phosphorylation	RLHMQRRSFIIQNIP HHHHHHHHHHHHCCC	24.00	24719451
278	Phosphorylation	QDEDMLRYMINLEVE CCHHHHHHHHHHCHH	9.82	19658100
288	Ubiquitination	NLEVEELKHPRAGCK HHCHHHHCCCCCCCE	55.64	23000965
295	Ubiquitination	KHPRAGCKFKFIFQG CCCCCCCEEEEEECC	51.15	23000965
297	Ubiquitination	PRAGCKFKFIFQGNP CCCCCEEEEEECCCC	24.05	23000965
313	Ubiquitination	FRNEGLVKEYERRSS CCCCCHHHEEECCCC	60.67	-
384	Phosphorylation	LWPNPLQYYLMGEGP CCCCHHHEECCCCCC	13.27	18083107
408	Phosphorylation	QPVESARSFRFQSG- CCCCCCCCCCCCCC-	22.08	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TSYL4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TSYL4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TSYL4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TFP11_HUMAN	TFIP11	physical	25416956
CK5P3_HUMAN	CDK5RAP3	physical	25416956
MIPO1_HUMAN	MIPOL1	physical	27173435

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.