F133A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F133A_HUMAN
• UniProt AC: Q8N9E0
• Protein Name: Protein FAM133A
• Gene Name: FAM133A
• Organism: Homo sapiens (Human).
• Sequence Length: 248
• Protein Sequence: MGKRDNRVAYMNPIAMARWRGPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	KRDNRVAYMNPIAMA CCCCCCEECCHHHHH	8.45	28796482
18	Methylation	MNPIAMARWRGPTQS CCHHHHHHCCCCCCC	15.56	-
52	Acetylation	KKQLENKKTGSKALA HHHHHCCCCCHHHHH	70.47	7696067
56	Acetylation	ENKKTGSKALAEFEE HCCCCCHHHHHHHHH	49.08	7696075
56	Ubiquitination	ENKKTGSKALAEFEE HCCCCCHHHHHHHHH	49.08	-
82	Phosphorylation	KSREKLLSGNESSSK HHHHHHHCCCCCHHH	50.43	30266825
86	Phosphorylation	KLLSGNESSSKKRER HHHCCCCCHHHHHHH	43.86	29396449
87	Phosphorylation	LLSGNESSSKKRERK HHCCCCCHHHHHHHH	39.74	27251275
88	Phosphorylation	LSGNESSSKKRERKK HCCCCCHHHHHHHHH	52.02	27251275
101	Phosphorylation	KKKRKKKSCRSSSSS HHHHHHHHHCCCCCC	24.52	30576142
104	Phosphorylation	RKKKSCRSSSSSSSS HHHHHHCCCCCCCCC	38.61	30576142
106	Phosphorylation	KKSCRSSSSSSSSDS HHHHCCCCCCCCCCC	35.17	30576142
107	Phosphorylation	KSCRSSSSSSSSDSS HHHCCCCCCCCCCCC	35.87	30576142
108	Phosphorylation	SCRSSSSSSSSDSSS HHCCCCCCCCCCCCC	35.87	-
111	Phosphorylation	SSSSSSSSDSSSSSS CCCCCCCCCCCCCCC	43.38	30576142
113	Phosphorylation	SSSSSSDSSSSSSDS CCCCCCCCCCCCCCC	33.78	-
115	Phosphorylation	SSSSDSSSSSSDSED CCCCCCCCCCCCCHH	37.89	-
116	Phosphorylation	SSSDSSSSSSDSEDE CCCCCCCCCCCCHHH	35.49	30576142
117	Phosphorylation	SSDSSSSSSDSEDEE CCCCCCCCCCCHHHH	39.86	30576142
118	Phosphorylation	SDSSSSSSDSEDEEK CCCCCCCCCCHHHHH	47.29	30576142
120	Phosphorylation	SSSSSSDSEDEEKKQ CCCCCCCCHHHHHHH	49.23	30576142
151	Phosphorylation	SSTHESESESKESVK CCCCCCHHHHHHHHH	57.35	28176443
153	Phosphorylation	THESESESKESVKKK CCCCHHHHHHHHHHH	51.51	28176443
162	Acetylation	ESVKKKKKSKDETEK HHHHHHHCCCHHHHH	72.17	164443
175	Phosphorylation	EKEKDVRSLSKKRKK HHHHHHHHHHHHHHH	36.52	-
177	Phosphorylation	EKDVRSLSKKRKKSY HHHHHHHHHHHHHCC	37.06	-
184	Phosphorylation	SKKRKKSYPDDKPLS HHHHHHCCCCCCCCC	21.40	-
191	Phosphorylation	YPDDKPLSSESSSES CCCCCCCCCCCCCCC	40.36	-
192	Phosphorylation	PDDKPLSSESSSESD CCCCCCCCCCCCCCH	49.53	30631047
198	Phosphorylation	SSESSSESDYEEDVQ CCCCCCCCHHHHHHH	47.65	30631047
223	Acetylation	EQAKEKVKKKKKKQH HHHHHHHHHHHHHHH	70.69	164149
225	Acetylation	AKEKVKKKKKKQHKK HHHHHHHHHHHHHHH	65.20	164151
226	Acetylation	KEKVKKKKKKQHKKH HHHHHHHHHHHHHHH	74.26	164153
227	Acetylation	EKVKKKKKKQHKKHS HHHHHHHHHHHHHHH	67.55	164155
247	Phosphorylation	KSGSSHKSR------ CCCCCCCCC------	37.49	25954137

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F133A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F133A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F133A_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of F133A_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.