SNX14_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SNX14_HUMAN
• UniProt AC: Q9Y5W7
• Protein Name: Sorting nexin-14
• Gene Name: SNX14
• Organism: Homo sapiens (Human).
• Sequence Length: 946
• Subcellular Localization: Lysosome membrane ; Multi-pass membrane protein . Late endosome membrane ; Multi-pass membrane protein . Cell projection, dendrite .
• Protein Description: Plays a role in maintaining normal neuronal excitability and synaptic transmission. May be involved in several stages of intracellular trafficking (By similarity). Required for autophagosome clearance, possibly by mediating the fusion of lysosomes with autophagosomes (Probable). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), a key component of late endosomes/lysosomes. [PubMed: 25848753 Does not bind phosphatidylinositol 3-phosphate (PtdIns(3P))]
• Protein Sequence: MVPWVRTMGQKLKQRLRLDVGREICRQYPLFCFLLLCLSAASLLLNRYIHILMIFWSFVAGVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLENYQPWLDLKISSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLIRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEFLQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKLNRGSLSLDDFRNTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTERKQNQNYFMEVMTVEGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEVTSVTSWM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Ubiquitination	WVRTMGQKLKQRLRL HHHCHHHHHHHHHHH	52.50	-
75	Ubiquitination	SLGPDSLLPNIFFTI HCCCCHHCCCEEEEE	3.36	21963094
76	Ubiquitination	LGPDSLLPNIFFTIK CCCCHHCCCEEEEEE	36.84	21963094
95	Ubiquitination	QLGLQELFPQGHSCA HCCCHHHCCCCCCCE	4.11	22817900
96	Ubiquitination	LGLQELFPQGHSCAV CCCHHHCCCCCCCEE	52.44	22817900
97	Ubiquitination	GLQELFPQGHSCAVC CCHHHCCCCCCCEEC	55.70	22817900
99	Ubiquitination	QELFPQGHSCAVCGK HHHCCCCCCCEECCC	17.92	22817900
100	Ubiquitination	ELFPQGHSCAVCGKV HHCCCCCCCEECCCE	15.59	22817900
110	Ubiquitination	VCGKVKCKRHRPSLL ECCCEEECCCCCCEE	45.59	23503661
111	Ubiquitination	CGKVKCKRHRPSLLL CCCEEECCCCCCEEE	40.28	23503661
114	Ubiquitination	VKCKRHRPSLLLENY EEECCCCCCEEECCC	24.17	23503661
115	Phosphorylation	KCKRHRPSLLLENYQ EECCCCCCEEECCCC	31.44	28122231
115	Ubiquitination	KCKRHRPSLLLENYQ EECCCCCCEEECCCC	31.44	23503661
116	Ubiquitination	CKRHRPSLLLENYQP ECCCCCCEEECCCCC	7.58	23503661
117	Ubiquitination	KRHRPSLLLENYQPW CCCCCCEEECCCCCC	7.09	23503661
127	Ubiquitination	NYQPWLDLKISSKVD CCCCCCCCCCCCCCC	5.07	21963094
128	Ubiquitination	YQPWLDLKISSKVDA CCCCCCCCCCCCCCC	39.96	21963094
132	Ubiquitination	LDLKISSKVDASLSE CCCCCCCCCCCHHHH	37.03	29967540
136 (in isoform 2)	Phosphorylation	-	28.15	25247763
139	Ubiquitination	KVDASLSEVLELVLE CCCCHHHHHHHHHHH	57.31	22817900
140	Ubiquitination	VDASLSEVLELVLEN CCCHHHHHHHHHHHH	4.53	22817900
141	Ubiquitination	DASLSEVLELVLENF CCHHHHHHHHHHHHC	3.55	22817900
143	Ubiquitination	SLSEVLELVLENFVY HHHHHHHHHHHHCCC	4.69	22817900
144	Ubiquitination	LSEVLELVLENFVYP HHHHHHHHHHHCCCC	4.62	22817900
147	Ubiquitination	VLELVLENFVYPWYR HHHHHHHHCCCCCCC	27.76	22817900
147 (in isoform 2)	Phosphorylation	-	27.76	25247763
148	Ubiquitination	LELVLENFVYPWYRD HHHHHHHCCCCCCCC	3.98	22817900
148 (in isoform 2)	Ubiquitination	-	3.98	-
149	Ubiquitination	ELVLENFVYPWYRDV HHHHHHCCCCCCCCC	9.40	22817900
150	Ubiquitination	LVLENFVYPWYRDVT HHHHHCCCCCCCCCC	5.50	22817900
151	Ubiquitination	VLENFVYPWYRDVTD HHHHCCCCCCCCCCC	19.13	22817900
152	Ubiquitination	LENFVYPWYRDVTDD HHHCCCCCCCCCCCC	5.32	22817900
154	Ubiquitination	NFVYPWYRDVTDDES HCCCCCCCCCCCCHH	28.23	23503661
155	Ubiquitination	FVYPWYRDVTDDESF CCCCCCCCCCCCHHH	31.78	23503661
158	Ubiquitination	PWYRDVTDDESFVDE CCCCCCCCCHHHHHH	58.49	23503661
159	Ubiquitination	WYRDVTDDESFVDEL CCCCCCCCHHHHHHH	44.04	23503661
160	Ubiquitination	YRDVTDDESFVDELR CCCCCCCHHHHHHHH	49.22	23503661
161	Ubiquitination	RDVTDDESFVDELRI CCCCCCHHHHHHHHH	37.25	23503661
162	Ubiquitination	DVTDDESFVDELRIT CCCCCHHHHHHHHHH	8.26	23503661
163	Ubiquitination	VTDDESFVDELRITL CCCCHHHHHHHHHHH	8.55	23503661
166	Ubiquitination	DESFVDELRITLRFF CHHHHHHHHHHHHHH	4.09	23503661
167	Ubiquitination	ESFVDELRITLRFFA HHHHHHHHHHHHHHH	20.14	23503661
168	Ubiquitination	SFVDELRITLRFFAS HHHHHHHHHHHHHHH	7.13	23503661
169	Ubiquitination	FVDELRITLRFFASV HHHHHHHHHHHHHHH	12.87	23503661
169 (in isoform 2)	Ubiquitination	-	12.87	-
188	Phosphorylation	IHKVDIPSIITKKLL HHCCCCCHHHHHHHH	27.27	29255136
190	Ubiquitination	KVDIPSIITKKLLKA CCCCCHHHHHHHHHH	5.61	29901268
191	Phosphorylation	VDIPSIITKKLLKAA CCCCHHHHHHHHHHH	22.06	29255136
191	Ubiquitination	VDIPSIITKKLLKAA CCCCHHHHHHHHHHH	22.06	22817900
192	Ubiquitination	DIPSIITKKLLKAAM CCCHHHHHHHHHHHH	30.89	21906983
193	Ubiquitination	IPSIITKKLLKAAMK CCHHHHHHHHHHHHH	50.86	22817900
194	Ubiquitination	PSIITKKLLKAAMKH CHHHHHHHHHHHHHH	6.72	22817900
195	Ubiquitination	SIITKKLLKAAMKHI HHHHHHHHHHHHHHH	4.94	22817900
196	Ubiquitination	IITKKLLKAAMKHIE HHHHHHHHHHHHHHH	44.53	21906983
201	Ubiquitination	LLKAAMKHIEVIVKA HHHHHHHHHHHHHHH	14.35	22817900
202	Ubiquitination	LKAAMKHIEVIVKAR HHHHHHHHHHHHHHH	3.64	22817900
206	Ubiquitination	MKHIEVIVKARQKVK HHHHHHHHHHHHHHC	4.85	23503661
207	Ubiquitination	KHIEVIVKARQKVKN HHHHHHHHHHHHHCC	27.08	23503661
210	Ubiquitination	EVIVKARQKVKNTEF HHHHHHHHHHCCCHH	60.81	23503661
211	Ubiquitination	VIVKARQKVKNTEFL HHHHHHHHHCCCHHH	50.01	23503661
212	Ubiquitination	IVKARQKVKNTEFLQ HHHHHHHHCCCHHHH	4.35	23503661
213	Ubiquitination	VKARQKVKNTEFLQQ HHHHHHHCCCHHHHH	66.25	21906983
224	Ubiquitination	FLQQAALEEYGPELH HHHHHHHHHHCCHHH	44.43	23503661
225	Ubiquitination	LQQAALEEYGPELHV HHHHHHHHHCCHHHH	57.55	23503661
238	Ubiquitination	HVALRSRRDELHYLR HHHHHCCCHHHHHHH	42.90	29901268
241	Ubiquitination	LRSRRDELHYLRKLT HHCCCHHHHHHHHHH	3.64	29901268
242	Ubiquitination	RSRRDELHYLRKLTE HCCCHHHHHHHHHHH	19.96	29901268
245	Ubiquitination	RDELHYLRKLTELLF CHHHHHHHHHHHHHH	25.44	22817900
246	Ubiquitination	DELHYLRKLTELLFP HHHHHHHHHHHHHHC	58.11	22817900
268	Ubiquitination	TDCRSLTLLIREILS CCCHHHHHHHHHHHC	4.55	23503661
269	Ubiquitination	DCRSLTLLIREILSG CCHHHHHHHHHHHCC	2.67	23503661
276	Ubiquitination	LIREILSGSVFLPSL HHHHHHCCCCCCCCC	25.12	23503661
277	Ubiquitination	IREILSGSVFLPSLD HHHHHCCCCCCCCCC	13.30	23503661
277 (in isoform 2)	Ubiquitination	-	13.30	-
282	Ubiquitination	SGSVFLPSLDFLADP CCCCCCCCCCCCCCC	42.59	29967540
285	Ubiquitination	VFLPSLDFLADPDTV CCCCCCCCCCCCCCC	8.00	29901268
286	Ubiquitination	FLPSLDFLADPDTVN CCCCCCCCCCCCCCC	5.43	29901268
290	Ubiquitination	LDFLADPDTVNHLLI CCCCCCCCCCCEEEE	64.93	29901268
293	Ubiquitination	LADPDTVNHLLIIFI CCCCCCCCEEEEEEE	23.37	29901268
294	Ubiquitination	ADPDTVNHLLIIFID CCCCCCCEEEEEEEC	20.06	29901268
313	Phosphorylation	EKATEPASPLVPFLQ HHCCCCCCCCHHHHH	29.49	27050516
320	Ubiquitination	SPLVPFLQKFAEPRN CCCHHHHHHHCCCCC	38.92	23503661
321	Ubiquitination	PLVPFLQKFAEPRNK CCHHHHHHHCCCCCC	49.00	21906983
334	Ubiquitination	NKKPSVLKLELKQIR CCCCCHHHHHHHHHH	37.45	29967540
337	Ubiquitination	PSVLKLELKQIREQQ CCHHHHHHHHHHHHH	7.78	29901268
338	Ubiquitination	SVLKLELKQIREQQD CHHHHHHHHHHHHHH	34.01	29901268
346	Ubiquitination	QIREQQDLLFRFMNF HHHHHHHHHHHHHHH	4.18	29967540
354	Ubiquitination	LFRFMNFLKQEGAVH HHHHHHHHHHCCCCH	4.80	29967540
356	Ubiquitination	RFMNFLKQEGAVHVL HHHHHHHHCCCCHHH	57.41	29967540
359	Ubiquitination	NFLKQEGAVHVLQFC HHHHHCCCCHHHHHH	6.36	29901268
361	Ubiquitination	LKQEGAVHVLQFCLT HHHCCCCHHHHHHEE	17.65	22817900
362	Ubiquitination	KQEGAVHVLQFCLTV HHCCCCHHHHHHEEH	3.45	21890473
364	Ubiquitination	EGAVHVLQFCLTVEE CCCCHHHHHHEEHHH	26.39	29967540
369	Ubiquitination	VLQFCLTVEEFNDRI HHHHHEEHHHHCHHH	4.24	23000965
370	Ubiquitination	LQFCLTVEEFNDRIL HHHHEEHHHHCHHHC	52.19	22817900
371	Ubiquitination	QFCLTVEEFNDRILR HHHEEHHHHCHHHCC	45.47	21890473
378	Ubiquitination	EFNDRILRPELSNDE HHCHHHCCHHCCCHH	21.92	23000965
397	Phosphorylation	HEELQKIYKTYCLDE HHHHHHHHHHHHCCC	12.33	-
398	Ubiquitination	EELQKIYKTYCLDES HHHHHHHHHHHCCCC	36.17	29967540
405	Ubiquitination	KTYCLDESIDKIRFD HHHHCCCCCCHHCCC	35.44	22817900
406	Ubiquitination	TYCLDESIDKIRFDP HHHCCCCCCHHCCCH	6.18	21890473
408	Ubiquitination	CLDESIDKIRFDPFI HCCCCCCHHCCCHHH	33.83	29967540
413	Ubiquitination	IDKIRFDPFIVEEIQ CCHHCCCHHHHHHHH	20.39	23000965
432	Ubiquitination	GPYIDVVKLQTMRCL CCCEEEEEHHHHHHH	34.42	21906983
435	Phosphorylation	IDVVKLQTMRCLFEA EEEEEHHHHHHHHHH	19.61	24719451
474	Phosphorylation	QLLRGAESPTRNSKL HHHCCCCCCCCCCCC	30.91	28102081
474	Ubiquitination	QLLRGAESPTRNSKL HHHCCCCCCCCCCCC	30.91	23503661
476	Phosphorylation	LRGAESPTRNSKLNR HCCCCCCCCCCCCCC	52.33	28102081
476	Ubiquitination	LRGAESPTRNSKLNR HCCCCCCCCCCCCCC	52.33	23503661
479	Ubiquitination	AESPTRNSKLNRGSL CCCCCCCCCCCCCCC	34.92	23503661
483	Ubiquitination	TRNSKLNRGSLSLDD CCCCCCCCCCCCHHH	46.65	23503661
485	Phosphorylation	NSKLNRGSLSLDDFR CCCCCCCCCCHHHHH	16.14	22617229
485	Ubiquitination	NSKLNRGSLSLDDFR CCCCCCCCCCHHHHH	16.14	23503661
487	Phosphorylation	KLNRGSLSLDDFRNT CCCCCCCCHHHHHHH	31.30	22617229
488	Ubiquitination	LNRGSLSLDDFRNTQ CCCCCCCHHHHHHHH	9.93	23503661
496	Methylation	DDFRNTQKRGESFGI HHHHHHHHHHHHCCC	61.40	115980771
500	Phosphorylation	NTQKRGESFGISRIG HHHHHHHHCCCCCCH	31.43	27251275
504	Phosphorylation	RGESFGISRIGSKIK HHHHCCCCCCHHHHC	20.44	29514088
508	Phosphorylation	FGISRIGSKIKGVFK CCCCCCHHHHCEEEE	28.92	24719451
518	Ubiquitination	KGVFKSTTMEGAMLP CEEEECCCCCCCCCC	21.95	23503661
520	Ubiquitination	VFKSTTMEGAMLPNY EEECCCCCCCCCCCC	41.53	23503661
523	Ubiquitination	STTMEGAMLPNYGVA CCCCCCCCCCCCCCC	10.59	23503661
540	Ubiquitination	EDDFIEEGIVVMEDD CCCCCCCCEEEECCC	12.76	23503661
543	Ubiquitination	FIEEGIVVMEDDSPV CCCCCEEEECCCCCC	3.08	23503661
548	Phosphorylation	IVVMEDDSPVEAVST EEEECCCCCCEECCC	43.07	14702039
549	Ubiquitination	VVMEDDSPVEAVSTP EEECCCCCCEECCCC	34.66	23503661
552	Ubiquitination	EDDSPVEAVSTPNTP CCCCCCEECCCCCCC	10.78	23503661
556	Ubiquitination	PVEAVSTPNTPRNLA CCEECCCCCCCCCHH	34.88	33845483
558	Phosphorylation	EAVSTPNTPRNLAAW EECCCCCCCCCHHHH	25.48	-
584	Ubiquitination	DPSSERKEKKERIPV CCCHHHHHHHHCCCE	75.48	23503661
587	Ubiquitination	SERKEKKERIPVFCI HHHHHHHHCCCEEEE	67.90	23503661
589	Ubiquitination	RKEKKERIPVFCIDV HHHHHHCCCEEEEEC	3.42	29967540
590	Ubiquitination	KEKKERIPVFCIDVE HHHHHCCCEEEEECC	21.25	29967540
595	Ubiquitination	RIPVFCIDVERNDRR CCCEEEEECCCCCCC	37.09	29967540
596	Ubiquitination	IPVFCIDVERNDRRA CCEEEEECCCCCCCC	3.64	29967540
601	Ubiquitination	IDVERNDRRAVGHEP EECCCCCCCCCCCCC	31.82	29967540
602	Ubiquitination	DVERNDRRAVGHEPE ECCCCCCCCCCCCCC	36.17	29967540
604	Ubiquitination	ERNDRRAVGHEPEHW CCCCCCCCCCCCCHH	8.35	33845483
607	Ubiquitination	DRRAVGHEPEHWSVY CCCCCCCCCCHHHHH	46.59	33845483
608	Ubiquitination	RRAVGHEPEHWSVYR CCCCCCCCCHHHHHH	32.83	33845483
615	Ubiquitination	PEHWSVYRRYLEFYV CCHHHHHHHHHHHHH	20.72	33845483
633	Ubiquitination	KLTEFHGAFPDAQLP HHCCCCCCCCCCCCC	12.29	29967540
639	Ubiquitination	GAFPDAQLPSKRIIG CCCCCCCCCCCCCCC	5.76	29967540
641	Phosphorylation	FPDAQLPSKRIIGPK CCCCCCCCCCCCCCC	43.06	24719451
642	Ubiquitination	PDAQLPSKRIIGPKN CCCCCCCCCCCCCCC	45.75	21906983
645	Ubiquitination	QLPSKRIIGPKNYEF CCCCCCCCCCCCHHH	10.05	29967540
648	Acetylation	SKRIIGPKNYEFLKS CCCCCCCCCHHHHHH	67.93	7681489
648	Ubiquitination	SKRIIGPKNYEFLKS CCCCCCCCCHHHHHH	67.93	29967540
651	Ubiquitination	IIGPKNYEFLKSKRE CCCCCCHHHHHHHHH	54.63	33845483
652	Ubiquitination	IGPKNYEFLKSKREE CCCCCHHHHHHHHHH	8.00	33845483
654	Acetylation	PKNYEFLKSKREEFQ CCCHHHHHHHHHHHH	60.29	7681499
654	Ubiquitination	PKNYEFLKSKREEFQ CCCHHHHHHHHHHHH	60.29	29967540
655	Ubiquitination	KNYEFLKSKREEFQE CCHHHHHHHHHHHHH	38.81	29967540
656	Acetylation	NYEFLKSKREEFQEY CHHHHHHHHHHHHHH	63.34	7681509
656	Ubiquitination	NYEFLKSKREEFQEY CHHHHHHHHHHHHHH	63.34	33845483
658	Ubiquitination	EFLKSKREEFQEYLQ HHHHHHHHHHHHHHH	67.89	22817900
659	Ubiquitination	FLKSKREEFQEYLQK HHHHHHHHHHHHHHH	57.58	21890473
660	Ubiquitination	LKSKREEFQEYLQKL HHHHHHHHHHHHHHH	5.99	21890473
663	Ubiquitination	KREEFQEYLQKLLQH HHHHHHHHHHHHHCC	12.03	33845483
666	Ubiquitination	EFQEYLQKLLQHPEL HHHHHHHHHHCCHHH	48.87	23000965
667	Ubiquitination	FQEYLQKLLQHPELS HHHHHHHHHCCHHHC	3.43	23000965
694	Ubiquitination	GGETQFLDKILPDVN CCCCHHHHHHCCCCC	36.92	33845483
695	Ubiquitination	GETQFLDKILPDVNL CCCHHHHHHCCCCCH	48.57	33845483
698	Ubiquitination	QFLDKILPDVNLGKI HHHHHHCCCCCHHHH	47.15	29967540
702	Ubiquitination	KILPDVNLGKIIKSV HHCCCCCHHHHHHCC	8.10	22817900
703	Ubiquitination	ILPDVNLGKIIKSVP HCCCCCHHHHHHCCC	17.57	21890473
703 (in isoform 2)	Ubiquitination	-	17.57	21890473
704	Ubiquitination	LPDVNLGKIIKSVPG CCCCCHHHHHHCCCC	44.41	21890473
704 (in isoform 3)	Ubiquitination	-	44.41	21890473
707	Ubiquitination	VNLGKIIKSVPGKLM CCHHHHHHCCCCHHH	49.20	29967540
710	Ubiquitination	GKIIKSVPGKLMKEK HHHHHCCCCHHHHHC	41.09	23000965
710 (in isoform 2)	Ubiquitination	-	41.09	-
711	Ubiquitination	KIIKSVPGKLMKEKG HHHHCCCCHHHHHCC	33.31	23000965
712	Ubiquitination	IIKSVPGKLMKEKGQ HHHCCCCHHHHHCCC	39.06	21890473
715	Ubiquitination	SVPGKLMKEKGQHLE CCCCHHHHHCCCCCH	67.71	33845483
718	Ubiquitination	GKLMKEKGQHLEPFI CHHHHHCCCCCHHHH	22.64	23000965
719	Ubiquitination	KLMKEKGQHLEPFIM HHHHHCCCCCHHHHH	49.40	23000965
725	Ubiquitination	GQHLEPFIMNFINSC CCCCHHHHHHHHHHC	3.01	33845483
731	Phosphorylation	FIMNFINSCESPKPK HHHHHHHHCCCCCCC	17.91	25627689
734	Phosphorylation	NFINSCESPKPKPSR HHHHHCCCCCCCCCC	42.42	25159151
745	Phosphorylation	KPSRPELTILSPTSE CCCCCCCEEECCCCC	20.43	23312004
745	Ubiquitination	KPSRPELTILSPTSE CCCCCCCEEECCCCC	20.43	22817900
746	Ubiquitination	PSRPELTILSPTSEN CCCCCCEEECCCCCC	5.84	21890473
747	Ubiquitination	SRPELTILSPTSENN CCCCCEEECCCCCCH	4.17	21890473
747 (in isoform 4)	Ubiquitination	-	4.17	21890473
748	Phosphorylation	RPELTILSPTSENNK CCCCEEECCCCCCHH	23.45	22199227
750	Phosphorylation	ELTILSPTSENNKKL CCEEECCCCCCHHHH	45.34	29523821
751	Phosphorylation	LTILSPTSENNKKLF CEEECCCCCCHHHHH	41.53	29523821
753	Ubiquitination	ILSPTSENNKKLFND EECCCCCCHHHHHHH	66.44	23000965
754	Ubiquitination	LSPTSENNKKLFNDL ECCCCCCHHHHHHHH	38.49	23000965
755	Ubiquitination	SPTSENNKKLFNDLF CCCCCCHHHHHHHHH	63.54	21890473
756	Ubiquitination	PTSENNKKLFNDLFK CCCCCHHHHHHHHHH	61.51	21906983
756 (in isoform 1)	Ubiquitination	-	61.51	21890473
762	Ubiquitination	KKLFNDLFKNNANRA HHHHHHHHHHCCCHH	9.92	23000965
763	Ubiquitination	KLFNDLFKNNANRAE HHHHHHHHHCCCHHH	57.50	23000965
771	Ubiquitination	NNANRAENTERKQNQ HCCCHHHHHHHHHHH	46.37	23503661
772	Ubiquitination	NANRAENTERKQNQN CCCHHHHHHHHHHHC	28.77	23503661
773	Ubiquitination	ANRAENTERKQNQNY CCHHHHHHHHHHHCC	70.26	23503661
774	Ubiquitination	NRAENTERKQNQNYF CHHHHHHHHHHHCCE	43.77	23503661
776	Ubiquitination	AENTERKQNQNYFME HHHHHHHHHHCCEEE	64.06	23503661
777	Ubiquitination	ENTERKQNQNYFMEV HHHHHHHHHCCEEEE	34.79	23503661
784	Ubiquitination	NQNYFMEVMTVEGVY HHCCEEEEEEEHHHH	2.34	33845483
815	Ubiquitination	LHHLLMGTRILFKNT HHHHHHHCHHHHHHH	10.69	23503661
816	Ubiquitination	HHLLMGTRILFKNTL HHHHHHCHHHHHHHH	20.20	23503661
817	Ubiquitination	HLLMGTRILFKNTLE HHHHHCHHHHHHHHH	5.50	23503661
818	Ubiquitination	LLMGTRILFKNTLEM HHHHCHHHHHHHHHH	4.51	23503661
820	Ubiquitination	MGTRILFKNTLEMYT HHCHHHHHHHHHHHH	45.65	23503661
820 (in isoform 2)	Ubiquitination	-	45.65	-
821	Ubiquitination	GTRILFKNTLEMYTD HCHHHHHHHHHHHHH	42.43	23503661
823	Ubiquitination	RILFKNTLEMYTDYY HHHHHHHHHHHHHHH	5.07	23503661
824	Ubiquitination	ILFKNTLEMYTDYYL HHHHHHHHHHHHHHH	28.27	23503661
825	Ubiquitination	LFKNTLEMYTDYYLQ HHHHHHHHHHHHHHH	4.99	23503661
826	Ubiquitination	FKNTLEMYTDYYLQC HHHHHHHHHHHHHHH	6.26	23503661
828	Ubiquitination	NTLEMYTDYYLQCKL HHHHHHHHHHHHHHH	16.76	23503661
829	Ubiquitination	TLEMYTDYYLQCKLE HHHHHHHHHHHHHHH	9.77	23503661
837	Ubiquitination	YLQCKLEQLFQEHRL HHHHHHHHHHHHHHH	59.00	23503661
838	Ubiquitination	LQCKLEQLFQEHRLV HHHHHHHHHHHHHHH	3.32	23503661
840	Ubiquitination	CKLEQLFQEHRLVSL HHHHHHHHHHHHHHH	54.93	23503661
841	Ubiquitination	KLEQLFQEHRLVSLI HHHHHHHHHHHHHHH	24.52	23503661
843	Ubiquitination	EQLFQEHRLVSLITL HHHHHHHHHHHHHHH	35.71	29967540
844	Ubiquitination	QLFQEHRLVSLITLL HHHHHHHHHHHHHHH	3.11	29967540
858	Ubiquitination	LRDAIFCENTEPRSL HHHHHHCCCCCCCCH	57.34	23503661
859	Ubiquitination	RDAIFCENTEPRSLQ HHHHHCCCCCCCCHH	51.42	23503661
860	Ubiquitination	DAIFCENTEPRSLQD HHHHCCCCCCCCHHH	25.69	23503661
861	Ubiquitination	AIFCENTEPRSLQDK HHHCCCCCCCCHHHH	50.74	23503661
863	Ubiquitination	FCENTEPRSLQDKQK HCCCCCCCCHHHHHH	43.71	23503661
864	Ubiquitination	CENTEPRSLQDKQKG CCCCCCCCHHHHHHH	40.89	23503661
867	Ubiquitination	TEPRSLQDKQKGAKQ CCCCCHHHHHHHHHH	61.72	23503661
868	Ubiquitination	EPRSLQDKQKGAKQT CCCCHHHHHHHHHHH	40.73	23503661
869	Ubiquitination	PRSLQDKQKGAKQTF CCCHHHHHHHHHHHH	58.67	23503661
870	Ubiquitination	RSLQDKQKGAKQTFE CCHHHHHHHHHHHHH	67.58	23503661
872	Ubiquitination	LQDKQKGAKQTFEEM HHHHHHHHHHHHHHH	14.07	23503661
873	Ubiquitination	QDKQKGAKQTFEEMM HHHHHHHHHHHHHHH	59.55	21906983
881	Ubiquitination	QTFEEMMNYIPDLLV HHHHHHHHHCHHHHH	30.21	23503661
882	Ubiquitination	TFEEMMNYIPDLLVK HHHHHHHHCHHHHHH	8.92	23503661
884	Ubiquitination	EEMMNYIPDLLVKCI HHHHHHCHHHHHHHH	18.81	23503661
884 (in isoform 2)	Ubiquitination	-	18.81	-
885	Ubiquitination	EMMNYIPDLLVKCIG HHHHHCHHHHHHHHC	42.97	23503661
887	Ubiquitination	MNYIPDLLVKCIGEE HHHCHHHHHHHHCCC	4.51	29967540
889	Ubiquitination	YIPDLLVKCIGEETK HCHHHHHHHHCCCCC	21.80	23503661
890	Ubiquitination	IPDLLVKCIGEETKY CHHHHHHHHCCCCCH	3.63	23503661
892	Ubiquitination	DLLVKCIGEETKYES HHHHHHHCCCCCHHH	35.84	23503661
893	Ubiquitination	LLVKCIGEETKYESI HHHHHHCCCCCHHHH	42.45	23503661
896	Ubiquitination	KCIGEETKYESIRLL HHHCCCCCHHHHHHH	50.75	29967540
924	Ubiquitination	TYVLLDIVIQELFPE HHHHHHHHHHHHHHH	3.54	23503661
925	Ubiquitination	YVLLDIVIQELFPEL HHHHHHHHHHHHHHH	2.42	23503661
927	Ubiquitination	LLDIVIQELFPELNK HHHHHHHHHHHHHHH	41.05	23503661
928	Ubiquitination	LDIVIQELFPELNKV HHHHHHHHHHHHHHH	5.07	23503661
933	Ubiquitination	QELFPELNKVQKEVT HHHHHHHHHHHHHHH	40.57	23503661
934	Ubiquitination	ELFPELNKVQKEVTS HHHHHHHHHHHHHHH	59.68	23503661
936	Ubiquitination	FPELNKVQKEVTSVT HHHHHHHHHHHHHHH	37.49	23503661
937	Ubiquitination	PELNKVQKEVTSVTS HHHHHHHHHHHHHHC	58.08	2190698

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SNX14_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SNX14_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SNX14_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SNX14_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 616354: Spinocerebellar ataxia, autosomal recessive, 20 (SCAR20)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Ubiquitylation

"Tryptic digestion of ubiquitin standards reveals an improved strategyfor identifying ubiquitinated proteins by mass spectrometry.";
Denis N.J., Vasilescu J., Lambert J.-P., Smith J.C., Figeys D.;
Proteomics 7:868-874(2007).
Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-196, AND MASSSPECTROMETRY.
PubMed: 17370265