SZT2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SZT2_HUMAN
• UniProt AC: Q5T011
• Protein Name: KICSTOR complex protein SZT2 {ECO:0000305}
• Gene Name: SZT2 {ECO:0000312|HGNC:HGNC:29040}
• Organism: Homo sapiens (Human).
• Sequence Length: 3432
• Subcellular Localization: Lysosome membrane . Peroxisome . Localization to lysosomes is amino acid-independent.
• Protein Description: As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose. [PubMed: 28199306]
• Protein Sequence: MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLSHLHQTVQATPQEMLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSQREVFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSGDLLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRVEVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGSTTPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPIPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPNSFYMVRIISKAPCMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQSKEPTPKVKRKGLGGAGGGSSPSKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLLSILTEVRLSEGFHFACSGEGIINMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQALHPRDAACIGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQMFFLLLAREPEGVPFAEGSCPANDMVLCLLHSCLGQELSDREIPLTPVDQAAFLSEVLRRTCHVPGAEGPLLGVHGIPKEQAVGSTQATGDSAFTSLSVGLPETLKPLISAQPPQWRCYARLVNPQHVFLTFLPATFSDVQRLAACGLEGPPQEETKPKFGDWSGAPSLKDLGGTGIKATKSHVPVLSVTLASDNAQNQGELSPPFRRDLQAYAGRQASQTESADGPRTRCPVYIYSCSLEALREQMVGMQPPQAPRDLIFRTQFLDHPSPSSAWMEPRYKEAANHCALLQEHAQRCYVRGLFRSLQQAQSVTSQDLLTAVDACEELLQEIDITPFLLALCGHTWGLPHAPPSPGPLSPGPFSSSMEEGAEPRERAILASESSIETEDLSEPEFQSTRVPGIPDPGPEISLTDVCQLRGEAHGALHSVIQEKFLEISRLHFRTVPSNPHYFFYCPPSSRREDEGPRDTVDRKISDLEFSEAELMGEEGDTSACCVVTESDPELEVEYRESRESDLGPAGLDSASLSDVDTVNPDEDSFSILGGDSPTGPESFLHDLPPLFLHLTCSVRLRGQHSSVPVCSLPTCLGQVLSSLEGPPVGGRVPLRDLSVTLDVFMLTLPLEVELPTASDPQHHRSTSESSASFPRSPGQPSSLRSDDGLGPPLPPPEEERHPGLSNLATPHRLAIETTMNEIRWLLEDEMVGALRRGGIPQSPALHRAAAHIHSSPGRSTCLRQTLPLSFVFGPERSLTQFKEEFRRLHLPGHVLLEDPDSGFFFVAAGQQPGGSHGEPSSAAWAWHSHEDRAEGIEGETLTASPQAPGSPEDSEGVPLISLPRVPQGGSQPGPSRGLSLMSSQGSVDSDHLGYDGGSSGSDSEGPNDTLGEKAPFTLRTPPGPAPPQPSLSGLPGPCLPDFWLIVRVLQDRVEVYAHARSLIREDGGPGTECRHLQQLLVRRVGEICREVNQRLLLQDLHDSHVCNSLLVAESEEDLWRSETPFHSRQRAPLPSDDYAADESCAPRGYLAATMQFVPGHFSCDVVWGTVIRVHSRLKMGPSMGVSRAIQALRSVLNAFSVVNRKNMFVYQERATKAVYYLRLLETSCSDRPWKGDALPPSLALSRSQEPIYSEEASGPRSPLDMVSSRSSDAARPVGQVDRHIQLLVHGVGQAGPEITDELVRVLCRRLDEATLDVITVMLVRNCKLTPADVEFIQPPGSLPSEVLHLALPTSCRPWLPALAWYLRQNLLIFLHSPKYTDSNSRNHFQHPLPPQGGLPDLDIYLYNKPGGQGTGGKGVACITLAFVDEGGAPLSLALWPPSSPGPPDPLREEEFEQLTQVIRCPVVVDSSSAQNGAPRLRLDVWEKGNISIVQLEEKLRGAARQALADAIIELQLLPASLCTEDTPTGSLRNGSLETKSSAGRASTFPPAPVPGEPVTPPSKAGRRSFWDMLSKTECGDLGSPKTTDDIVLDRPEDTRGRRRHKTESVRTPGGAERAPGSDSGAQRQKRRTTQLEEGEVGTLHPVFARVAQRWMEFMVQIGCASVSRSSAHMVSRFLLPSILSEFTALVTSMAGDTSVRIFEQHLGSEPEIFGPCSPGQLGPSPRPAAERHLLLLGRNFLQWRRPTQQAAKAMQRFEPGGDGSSGRNAPRQRLLLLEVVDKKLQLLTYNWAPDLGAALGRALVRLVQWQNARAHLIFCLLSQKLGLFHHYGQLDFPVRDEKEPNPFLLPTMEVETLIRSASPPLSREQGRLSGSSRGGGPLPLDTFPFDEALRDITAARPSSVLGPVPRPPDPVTYHGQQFLEIKMAERRELERQMKMENLFVTWQQRSTPATMPISAGELETLKQSSRLVHYCATAMLFDPAAWLHGPPETSGPPDGQRRHRPESGSGSREAPTSCESLDVSPPGAREEPWLKELSLAFLQQYVQYLQSIGFVLVPLRPPSPARSTSRPRAMAILGTEGRGSFSCPKTKTDGSPKSTSSPVTTYHLQRALPGGIILMELAFQGCYFCVKQFALECSRIPMGQAVNSQLSMLFTEECDKVRDLMHVHSFSYDFHLRLVHQHVLGAHLVLRHGYHLTTFLRHFLAHHPDGPHFGRNHIYQGTLELPTPLIAAHQLYNYVADHASSYHMKPLRMARPGGPEHNEYALVSAWHSSGSYLDSEGLRHQDDFDVSLLVCHCAAPFEEQGEAERHVLRLQFFVVLTSQRELFPRLTADMRRFRKPPRLPPEPEAPGSSAGSPGEASGLILAPGPAPLFPPLAAEVGMARARLAQLVRLAGGHCRRDTLWKRLFLLEPPGPDRLRLGGRLALAELEELLEAVHAKSIGDIDPQLDCFLSMTVSWYQSLIKVLLSRFPQSCRHFQSPDLGTQYLVVLNQKFTDCFVLVFLDSHLGKTSLTVVFREPFPVQPQDSESPPAQLVSTYHHLESVINTACFTLWTRLL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MASERPEPEV -----CCCCCCCCHH	46.10	29507054
27	Phosphorylation	MKKDYRISRNVRLAW EECCCCCCHHHHHHH	14.59	24505115
205	Phosphorylation	ATMLQQQYDPQSQAE HHHHHHHCCCCHHHC	25.83	27732954
209	Phosphorylation	QQQYDPQSQAEDQSP HHHCCCCHHHCCCCC	36.42	27732954
215	Phosphorylation	QSQAEDQSPDSGDLL CHHHCCCCCCCCCCC	42.89	25159151
218	Phosphorylation	AEDQSPDSGDLLGRK HCCCCCCCCCCCCHH	37.28	27732954
229	Phosphorylation	LGRKVGVSMVTADLG CCHHHCCCHHHCCHH	11.12	22617229
286	Phosphorylation	LNQLRSGTVACSFVQ HHHHHCCCEEEEEEE	13.23	22798277
401	Phosphorylation	EVPADLVSTVSVRLR CCCHHHEEEEEEEEC	30.32	-
457	Phosphorylation	EPEGPRVTRVEVTME CCCCCCEEEEEEEEE	30.21	24719451
619	Phosphorylation	ISHSSLTSLLRDWSS ECHHHHHHHHCCCCC	30.60	24719451
699	Phosphorylation	RFPHRVQSKEPTPKV HCCCCCCCCCCCCCC	35.81	24719451
703	Phosphorylation	RVQSKEPTPKVKRKG CCCCCCCCCCCCCCC	36.51	24719451
718	Phosphorylation	LGGAGGGSSPSKSPP CCCCCCCCCCCCCCC	42.21	29255136
719	Phosphorylation	GGAGGGSSPSKSPPV CCCCCCCCCCCCCCC	36.15	29255136
721	Phosphorylation	AGGGSSPSKSPPVLG CCCCCCCCCCCCCCC	47.95	29255136
723	Phosphorylation	GGSSPSKSPPVLGPQ CCCCCCCCCCCCCCC	38.48	25159151
755	Acetylation	KLLIRYEKLPLDYRA HHHHHHHCCCCCCCC	46.61	27452117
755	Ubiquitination	KLLIRYEKLPLDYRA HHHHHHHCCCCCCCC	46.61	-
760	Phosphorylation	YEKLPLDYRAPFLLT HHCCCCCCCCCEEEE	19.16	-
783	Phosphorylation	LVSGRSASSSLASLS CCCCCCCCHHHHHHH	23.00	30576142
785	Phosphorylation	SGRSASSSLASLSRY CCCCCCHHHHHHHHH	26.01	30576142
788	Phosphorylation	SASSSLASLSRYLYH CCCHHHHHHHHHHHH	31.97	27174698
790	Phosphorylation	SSSLASLSRYLYHQR CHHHHHHHHHHHHHH	19.18	27174698
1117	Phosphorylation	TLKPLISAQPPQWRC CHHHHHHCCCCCEEE	20.93	27251275
1119	Ubiquitination	KPLISAQPPQWRCYA HHHHHCCCCCEEEEE	23.83	29967540
1127	Ubiquitination	PQWRCYARLVNPQHV CCEEEEEEECCHHHH	16.82	29967540
1152	Phosphorylation	DVQRLAACGLEGPPQ HHHHHHHCCCCCCCC	5.48	24719451
1163	Ubiquitination	GPPQEETKPKFGDWS CCCCHHCCCCCCCCC	49.87	-
1168	Phosphorylation	ETKPKFGDWSGAPSL HCCCCCCCCCCCCCH	39.23	33259812
1174	Phosphorylation	GDWSGAPSLKDLGGT CCCCCCCCHHHHCCC	47.74	28555341
1185	Phosphorylation	LGGTGIKATKSHVPV HCCCCCCCCCCCCCE	20.52	24719451
1188	Phosphorylation	TGIKATKSHVPVLSV CCCCCCCCCCCEEEE	25.93	24719451
1196	Phosphorylation	HVPVLSVTLASDNAQ CCCEEEEEEECCCCC	17.15	-
1199	Phosphorylation	VLSVTLASDNAQNQG EEEEEEECCCCCCCC	34.21	27732954
1209	Phosphorylation	AQNQGELSPPFRRDL CCCCCCCCCCHHHHH	26.65	29507054
1219	Phosphorylation	FRRDLQAYAGRQASQ HHHHHHHHCCCCCCC	9.16	27251275
1225	Phosphorylation	AYAGRQASQTESADG HHCCCCCCCCCCCCC	29.33	28857561
1227	Phosphorylation	AGRQASQTESADGPR CCCCCCCCCCCCCCC	29.43	25262027
1229	Phosphorylation	RQASQTESADGPRTR CCCCCCCCCCCCCCC	34.74	24114839
1242	Phosphorylation	TRCPVYIYSCSLEAL CCCCEEEEECCHHHH	5.97	24719451
1245	Phosphorylation	PVYIYSCSLEALREQ CEEEEECCHHHHHHH	24.25	24719451
1269	Phosphorylation	PRDLIFRTQFLDHPS CHHHHEEECCCCCCC	16.96	27732954
1276	Phosphorylation	TQFLDHPSPSSAWME ECCCCCCCCCHHCCC	33.71	27732954
1278	Phosphorylation	FLDHPSPSSAWMEPR CCCCCCCCHHCCCHH	36.71	27732954
1279	Phosphorylation	LDHPSPSSAWMEPRY CCCCCCCHHCCCHHH	29.36	27732954
1331	Phosphorylation	LTAVDACEELLQEID HHHHHHHHHHHHHCC	54.09	24719451
1332	Phosphorylation	TAVDACEELLQEIDI HHHHHHHHHHHHCCC	55.45	27251275
1339	Phosphorylation	ELLQEIDITPFLLAL HHHHHCCCHHHHHHH	6.91	27251275
1359	Phosphorylation	GLPHAPPSPGPLSPG CCCCCCCCCCCCCCC	41.24	26074081
1364	Phosphorylation	PPSPGPLSPGPFSSS CCCCCCCCCCCCCCC	30.83	26074081
1388	Phosphorylation	RAILASESSIETEDL HHHHHHCCCCCCCCC	33.83	24719451
1389	Phosphorylation	AILASESSIETEDLS HHHHHCCCCCCCCCC	22.01	26657352
1392	Phosphorylation	ASESSIETEDLSEPE HHCCCCCCCCCCCCC	32.88	27251275
1396	Phosphorylation	SIETEDLSEPEFQST CCCCCCCCCCCHHHC	64.52	26657352
1402	Phosphorylation	LSEPEFQSTRVPGIP CCCCCHHHCCCCCCC	24.41	24719451
1403	Phosphorylation	SEPEFQSTRVPGIPD CCCCHHHCCCCCCCC	25.54	27251275
1407	Phosphorylation	FQSTRVPGIPDPGPE HHHCCCCCCCCCCCC	41.00	24719451
1416	Phosphorylation	PDPGPEISLTDVCQL CCCCCCCCHHHHHHH	24.45	27251275
1459	Phosphorylation	SNPHYFFYCPPSSRR CCCCEEEECCCCCCC	8.31	24719451
1464	Phosphorylation	FFYCPPSSRREDEGP EEECCCCCCCCCCCC	40.92	24719451
1480	Phosphorylation	DTVDRKISDLEFSEA CCHHHHHHHCCCCHH	38.90	24275569
1583	Phosphorylation	RGQHSSVPVCSLPTC CCCCCCCCCCCCCCH	24.28	27251275
1584	Phosphorylation	GQHSSVPVCSLPTCL CCCCCCCCCCCCCHH	3.03	24719451
1585	Phosphorylation	QHSSVPVCSLPTCLG CCCCCCCCCCCCHHH	2.57	27251275
1594	Phosphorylation	LPTCLGQVLSSLEGP CCCHHHHHHHHCCCC	5.48	27251275
1615	Phosphorylation	PLRDLSVTLDVFMLT CHHHCEEEEEEEEEE	17.54	-
1633	Phosphorylation	EVELPTASDPQHHRS EEECCCCCCCCCCCC	52.91	-
1640	Phosphorylation	SDPQHHRSTSESSAS CCCCCCCCCCCCCCC	31.74	30266825
1641	Phosphorylation	DPQHHRSTSESSASF CCCCCCCCCCCCCCC	36.15	30266825
1642	Phosphorylation	PQHHRSTSESSASFP CCCCCCCCCCCCCCC	36.41	30266825
1644	Phosphorylation	HHRSTSESSASFPRS CCCCCCCCCCCCCCC	30.85	30266825
1645	Phosphorylation	HRSTSESSASFPRSP CCCCCCCCCCCCCCC	24.71	30266825
1647	Phosphorylation	STSESSASFPRSPGQ CCCCCCCCCCCCCCC	37.42	30108239
1651	Phosphorylation	SSASFPRSPGQPSSL CCCCCCCCCCCCCCC	33.35	9455484
1656	Phosphorylation	PRSPGQPSSLRSDDG CCCCCCCCCCCCCCC	33.83	23927012
1657	Phosphorylation	RSPGQPSSLRSDDGL CCCCCCCCCCCCCCC	34.19	27251275
1660	Phosphorylation	GQPSSLRSDDGLGPP CCCCCCCCCCCCCCC	45.40	27251275
1692	Phosphorylation	PHRLAIETTMNEIRW HHHHHHHHHHHHHHH	25.82	30576142
1693	Phosphorylation	HRLAIETTMNEIRWL HHHHHHHHHHHHHHH	12.76	30576142
1700	Ubiquitination	TMNEIRWLLEDEMVG HHHHHHHHHHHHHHH	2.42	29967540
1717	Phosphorylation	RRGGIPQSPALHRAA HHCCCCCCHHHHHHH	13.54	27067055
1762	Phosphorylation	QFKEEFRRLHLPGHV HHHHHHHHCCCCCCE	31.60	24719451
1768	Phosphorylation	RRLHLPGHVLLEDPD HHCCCCCCEEEECCC	12.71	24719451
1815	Phosphorylation	AEGIEGETLTASPQA CCCCCCCEEEECCCC	40.02	25850435
1817	Phosphorylation	GIEGETLTASPQAPG CCCCCEEEECCCCCC	32.29	29116813
1819	Phosphorylation	EGETLTASPQAPGSP CCCEEEECCCCCCCC	16.59	30278072
1825	Phosphorylation	ASPQAPGSPEDSEGV ECCCCCCCCCCCCCC	24.85	30278072
1829	Phosphorylation	APGSPEDSEGVPLIS CCCCCCCCCCCCCEE	34.29	25850435
1836	Phosphorylation	SEGVPLISLPRVPQG CCCCCCEECCCCCCC	39.75	24719451
1838	Phosphorylation	GVPLISLPRVPQGGS CCCCEECCCCCCCCC	28.56	24719451
1854	Phosphorylation	PGPSRGLSLMSSQGS CCCCCCCCCCCCCCC	25.50	28111955
1857	Phosphorylation	SRGLSLMSSQGSVDS CCCCCCCCCCCCCCC	25.46	28111955
1858	Phosphorylation	RGLSLMSSQGSVDSD CCCCCCCCCCCCCCC	25.29	28111955
1861	Phosphorylation	SLMSSQGSVDSDHLG CCCCCCCCCCCCCCC	18.34	28111955
1864	Phosphorylation	SSQGSVDSDHLGYDG CCCCCCCCCCCCCCC	25.44	28111955
1869	Phosphorylation	VDSDHLGYDGGSSGS CCCCCCCCCCCCCCC	20.13	28111955
1873	Phosphorylation	HLGYDGGSSGSDSEG CCCCCCCCCCCCCCC	36.74	28111955
1874	Phosphorylation	LGYDGGSSGSDSEGP CCCCCCCCCCCCCCC	45.66	28111955
1876	Phosphorylation	YDGGSSGSDSEGPND CCCCCCCCCCCCCCC	39.65	28111955
1878	Phosphorylation	GGSSGSDSEGPNDTL CCCCCCCCCCCCCCC	46.26	28111955
1884	Phosphorylation	DSEGPNDTLGEKAPF CCCCCCCCCCCCCCC	43.21	28111955
1892	Phosphorylation	LGEKAPFTLRTPPGP CCCCCCCEECCCCCC	17.80	24719451
1895	Phosphorylation	KAPFTLRTPPGPAPP CCCCEECCCCCCCCC	36.63	24719451
2010	Phosphorylation	RQRAPLPSDDYAADE CCCCCCCCCCCCCCC	51.28	27642862
2013	Phosphorylation	APLPSDDYAADESCA CCCCCCCCCCCCCCC	14.53	27642862
2065	Phosphorylation	MGVSRAIQALRSVLN CHHHHHHHHHHHHHH	33.10	27251275
2075	Phosphorylation	RSVLNAFSVVNRKNM HHHHHHHHHHCCCCC	23.81	27251275
2120	Phosphorylation	LPPSLALSRSQEPIY CCHHHHCCCCCCCCC	25.03	24719451
2122	Phosphorylation	PSLALSRSQEPIYSE HHHHCCCCCCCCCCC	35.20	21945579
2127	Phosphorylation	SRSQEPIYSEEASGP CCCCCCCCCCCCCCC	22.27	21945579
2128	Phosphorylation	RSQEPIYSEEASGPR CCCCCCCCCCCCCCC	29.67	21945579
2132	Phosphorylation	PIYSEEASGPRSPLD CCCCCCCCCCCCCCH	53.24	26657352
2136	Phosphorylation	EEASGPRSPLDMVSS CCCCCCCCCCHHHCC	32.71	28348404
2142	Phosphorylation	RSPLDMVSSRSSDAA CCCCHHHCCCCCCCC	17.25	28450419
2143	Phosphorylation	SPLDMVSSRSSDAAR CCCHHHCCCCCCCCC	25.44	28450419
2146	Phosphorylation	DMVSSRSSDAARPVG HHHCCCCCCCCCCCC	30.11	16674116
2232	Phosphorylation	ALPTSCRPWLPALAW HCCCCCCCHHHHHHH	41.08	27251275
2279	Phosphorylation	GLPDLDIYLYNKPGG CCCCCEEEEECCCCC	11.64	28348404
2289	Phosphorylation	NKPGGQGTGGKGVAC CCCCCCCCCCCCEEE	34.57	28348404
2346	Phosphorylation	CPVVVDSSSAQNGAP CCEEECCCCCCCCCC	25.81	24114839
2377	Phosphorylation	LEEKLRGAARQALAD HHHHHHHHHHHHHHH	7.95	24719451
2386	Phosphorylation	RQALADAIIELQLLP HHHHHHHHHHHHCCC	2.30	27251275
2401	Phosphorylation	ASLCTEDTPTGSLRN HHHCCCCCCCCCCCC	19.27	27251275
2434	Phosphorylation	PVPGEPVTPPSKAGR CCCCCCCCCCCHHCC	39.95	25850435
2437	Phosphorylation	GEPVTPPSKAGRRSF CCCCCCCCHHCCCCH	36.02	25850435
2443	Phosphorylation	PSKAGRRSFWDMLSK CCHHCCCCHHHHHHC	29.36	28348404
2450	Phosphorylation	SFWDMLSKTECGDLG CHHHHHHCCCCCCCC	44.36	18491316
2451	Phosphorylation	FWDMLSKTECGDLGS HHHHHHCCCCCCCCC	32.88	18491316
2458	Phosphorylation	TECGDLGSPKTTDDI CCCCCCCCCCCCCCC	30.44	21815630
2486	Phosphorylation	HKTESVRTPGGAERA CCCCCCCCCCCCCCC	24.91	25159151
2488	Phosphorylation	TESVRTPGGAERAPG CCCCCCCCCCCCCCC	47.53	24719451
2507	Phosphorylation	AQRQKRRTTQLEEGE HHHHHCCCCCCCCCC	23.95	18491316
2508	Phosphorylation	QRQKRRTTQLEEGEV HHHHCCCCCCCCCCC	29.37	18491316
2545	Phosphorylation	CASVSRSSAHMVSRF CCCCCHHHHHHHHHH	22.53	24719451
2680	Phosphorylation	ALGRALVRLVQWQNA HHHHHHHHHHHHHHH	29.96	24719451
2735	Phosphorylation	EVETLIRSASPPLSR HHHHHHHHCCCCCCH	26.55	30266825
2737	Phosphorylation	ETLIRSASPPLSREQ HHHHHHCCCCCCHHH	28.44	24719451
2741	Phosphorylation	RSASPPLSREQGRLS HHCCCCCCHHHCCCC	39.27	30266825
2825	Phosphorylation	FVTWQQRSTPATMPI CCEECCCCCCCCCCC	34.11	28270605
2826	Phosphorylation	VTWQQRSTPATMPIS CEECCCCCCCCCCCC	21.09	28270605
2829	Phosphorylation	QQRSTPATMPISAGE CCCCCCCCCCCCHHH	25.36	28270605
2833	Phosphorylation	TPATMPISAGELETL CCCCCCCCHHHHHHH	25.09	28270605
2839	Phosphorylation	ISAGELETLKQSSRL CCHHHHHHHHHHHHH	52.45	28270605
2843	Phosphorylation	ELETLKQSSRLVHYC HHHHHHHHHHHHHHH	18.81	28270605
2844	Phosphorylation	LETLKQSSRLVHYCA HHHHHHHHHHHHHHH	27.43	28270605
2897	Phosphorylation	PTSCESLDVSPPGAR CCCCCCCCCCCCCCC	48.40	24719451
2899	Phosphorylation	SCESLDVSPPGAREE CCCCCCCCCCCCCCC	25.66	21815630
2902	Phosphorylation	SLDVSPPGAREEPWL CCCCCCCCCCCCHHH	40.42	24719451
2944	Phosphorylation	PSPARSTSRPRAMAI CCCCCCCCCCCEEEE	41.35	22210691
2954	Phosphorylation	RAMAILGTEGRGSFS CEEEECCCCCCCCCC	31.64	24719451
2959	Phosphorylation	LGTEGRGSFSCPKTK CCCCCCCCCCCCCCC	16.78	28857561
2961	Phosphorylation	TEGRGSFSCPKTKTD CCCCCCCCCCCCCCC	31.07	28857561
3227	Phosphorylation	PEPEAPGSSAGSPGE CCCCCCCCCCCCCCC	18.89	22210691
3228	Phosphorylation	EPEAPGSSAGSPGEA CCCCCCCCCCCCCCC	42.43	22210691
3231	Phosphorylation	APGSSAGSPGEASGL CCCCCCCCCCCCCCE	29.46	22210691
3236	Phosphorylation	AGSPGEASGLILAPG CCCCCCCCCEEECCC	29.81	22210691
3336	Phosphorylation	MTVSWYQSLIKVLLS HHHHHHHHHHHHHHH	19.16	24719451
3386	Phosphorylation	DSHLGKTSLTVVFRE CCCCCCEEEEEEECC	26.06	-
3402	Phosphorylation	FPVQPQDSESPPAQL CCCCCCCCCCCCHHH	34.42	-
3404	Phosphorylation	VQPQDSESPPAQLVS CCCCCCCCCCHHHHH	39.89	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SZT2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SZT2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SZT2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SZT2_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 615476: Epileptic encephalopathy, early infantile, 18 (EIEE18)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.