CC189_HUMAN - dbPTM
CC189_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CC189_HUMAN
UniProt AC A1A4V9
Protein Name Coiled-coil domain-containing protein 189
Gene Name CCDC189
Organism Homo sapiens (Human).
Sequence Length 331
Subcellular Localization
Protein Description
Protein Sequence MLNRKTSHFLGMRVQSELEHLSELRREAGKDRSSVHGSAARTRASVRTQWTTAAAAKADEDPGANLFPPPLPRPRICMWKYLDVHSMHQLEKTTNAEMREVLAELLELGCPEQSLRDAITLDLFCHALIFCRQQGFSLEQTSAACALLQDLHKACIATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALEDYVVNTYFRHFKLYKYVFTPQVRLDLSLTYMGLQPPKLWPESETEKEESKEMEEQAVTPQKEELETVAPPEPEPSHIHVLRAYIKTQVNKELEQLQGLVEERLKASEERLSSKLTALERPFQLPPGKGKSKTK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
34PhosphorylationEAGKDRSSVHGSAAR
HHCCCCCHHCHHHHH
-
38PhosphorylationDRSSVHGSAARTRAS
CCCHHCHHHHHHHHH
-
200PhosphorylationQLLALEDYVVNTYFR
HHHHHHHHHHHHHHH
28270605
204PhosphorylationLEDYVVNTYFRHFKL
HHHHHHHHHHHHCEE
28270605
205PhosphorylationEDYVVNTYFRHFKLY
HHHHHHHHHHHCEEE
28270605
212PhosphorylationYFRHFKLYKYVFTPQ
HHHHCEEEEEEECCC
24719451
214PhosphorylationRHFKLYKYVFTPQVR
HHCEEEEEEECCCEE
24719451
225PhosphorylationPQVRLDLSLTYMGLQ
CCEEEEEEEEECCCC
28509920
227PhosphorylationVRLDLSLTYMGLQPP
EEEEEEEEECCCCCC
-
235UbiquitinationYMGLQPPKLWPESET
ECCCCCCCCCCCCCC
-
240PhosphorylationPPKLWPESETEKEES
CCCCCCCCCCHHHHH
28122231
242PhosphorylationKLWPESETEKEESKE
CCCCCCCCHHHHHHH
28122231
247PhosphorylationSETEKEESKEMEEQA
CCCHHHHHHHHHHHC
29888752
273PhosphorylationAPPEPEPSHIHVLRA
CCCCCCCCHHHHHHH
25693802
288UbiquitinationYIKTQVNKELEQLQG
HHHHHHHHHHHHHHH
-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CC189_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CC189_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CC189_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SG1D2_HUMANSCGB1D2physical
28514442

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CC189_HUMAN

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Related Literatures of Post-Translational Modification

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