dbPTM

NU205_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NU205_HUMAN
UniProt AC	Q92621
Protein Name	Nuclear pore complex protein Nup205
Gene Name	NUP205
Organism	Homo sapiens (Human).
Sequence Length	2012
Subcellular Localization	Nucleus membrane Peripheral membrane protein . Nucleus, nuclear pore complex . Localized near the center, on both the cytoplasmic and nuclear side, of the NPC core structure.
Protein Description	Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. [PubMed: 9348540 May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC]
Protein Sequence	MATPLAVNSAASLWGPYKDIWHKVGNALWRRQPEAVHLLDKILKKHKPDFISLFKNPPKNVQQHEKVQKASTEGVAIQGQQGTRLLPEQLIKEAFILSDLFDIGELAAVELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCIANSLKALIQSRRGKTWTLELSPELASMTTRFTDELMEQGLTYKVLTLVSQIDVNNEFEKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSPLGKEDTLLLIGHLERVTVEANGSLDAVNLALLMALLYCFDISFIEQSTEERDDMIHQLPLLTEKQYIATIHSRLQDSQLWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAMAELAIADNVFLFLMESVVVSEYFYQEEFYIRRVHNLITDFLALMPMKVKQLRNRADEDARMIHMSMQMGNEPPISLRRDLEHLMLLIGELYKKNPFHLELALEYWCPTEPLQTPTIMGSYLGVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSSHVENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAFLQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLKTLAAFGKSPEIAASLWQSLEYTQILQTVRIPSQRQAIGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFPSNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQLEDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKKHLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVCPLEQLLQGINPRTKKADNVVNIARYLYHGNTNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSISQKLMAGFVECLDCEDAEEFVRLEEGSELEKKLVAIRHETRIHILNLLITSLECNPPNLALYLLGFELKKPVSTTNLQDPGVLGCPRTCLHAILNILEKGTEGRTGPVAVRESPQLAELCYQVIYQLCACSDTSGPTMRYLRTSQDFLFSQLQYLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLLHLLLDDMPVKPYSDGEGGIEDENRSVSGFLHFDTATKVRRKILNILDSIDFSQEIPEPLQLDFFDRAQIEQVIANCEHKNLRGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEISTVLQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQDLIQAEDRQLIIRDILQDVHDKILDDEAAQELMPVVAGAVFTLTAHLSQAVLTEQKETSVLGPAEAHYAFMLDSCFTSPPPEENPLVGFASIGDSSLYIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDTLEAAKKTMWERLTAPEDVFSKLQRENIAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLVEDDRTLQSLLTPQPPLLKALYTYESKMAFLTRVAKIQQGALELLRSGVIVRLAQCQVYDMRPETDPQSMFGMRDPPMFIPTPVDRYRQILLPALQLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSAGSLQELALLTGIISKAALPGILSELDVDVNEGSLMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKFQDDNVEGDKVSKKDEIELAMQQICANVMEYCQSLMLQSSPTFQHAVCLFTPSLSETVNRDGPRQDTQAPVVPYWRLPGLGIIIYLLKQSANDFFSYYDSHRQSVSKLQNVEQLPPDEIKELCQSVMPAGVDKISTAQKYVLARRRLVKVINNRAKLLSLCSFIIETCLFILWRHLEYYLLHCMPTDSQDSLFASRTLFKSRRLQDSFASETNLDFRSGLAIVSQHDLDQLQADAINAFGESLQKKLLDIEGLYSKVRSRYSFIQALVRRIRGLLRISRN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MATPLAVNS ------CCCCCCCCH	29.27	22223895
3	Phosphorylation	-----MATPLAVNSA -----CCCCCCCCHH	30.60	28348404
9	Phosphorylation	ATPLAVNSAASLWGP CCCCCCCHHHHHHCC	20.72	27732954
12	Phosphorylation	LAVNSAASLWGPYKD CCCCHHHHHHCCHHH	25.11	27732954
17	Phosphorylation	AASLWGPYKDIWHKV HHHHHCCHHHHHHHH	19.84	27732954
18	Ubiquitination	ASLWGPYKDIWHKVG HHHHCCHHHHHHHHH	45.96	22817900
23	Ubiquitination	PYKDIWHKVGNALWR CHHHHHHHHHHHHHH	36.52	21890473
23	Ubiquitination	PYKDIWHKVGNALWR CHHHHHHHHHHHHHH	36.52	21906983
41	Ubiquitination	EAVHLLDKILKKHKP HHHHHHHHHHHHHCC	50.32	21890473
41	Acetylation	EAVHLLDKILKKHKP HHHHHHHHHHHHHCC	50.32	19608861
41	Ubiquitination	EAVHLLDKILKKHKP HHHHHHHHHHHHHCC	50.32	23000965
44	Ubiquitination	HLLDKILKKHKPDFI HHHHHHHHHHCCCHH	57.20	23000965
45	Ubiquitination	LLDKILKKHKPDFIS HHHHHHHHHCCCHHH	54.11	23000965
47	Acetylation	DKILKKHKPDFISLF HHHHHHHCCCHHHHC	55.98	26051181
47	Ubiquitination	DKILKKHKPDFISLF HHHHHHHCCCHHHHC	55.98	23000965
52	Phosphorylation	KHKPDFISLFKNPPK HHCCCHHHHCCCCCC	27.96	24719451
55	Acetylation	PDFISLFKNPPKNVQ CCHHHHCCCCCCCHH	74.06	26051181
55	Ubiquitination	PDFISLFKNPPKNVQ CCHHHHCCCCCCCHH	74.06	23000965
59	Ubiquitination	SLFKNPPKNVQQHEK HHCCCCCCCHHHHHH	71.64	23000965
66	Ubiquitination	KNVQQHEKVQKASTE CCHHHHHHHHHHHCC	48.09	23000965
69	Ubiquitination	QQHEKVQKASTEGVA HHHHHHHHHHCCCCE	47.49	23000965
72	Phosphorylation	EKVQKASTEGVAIQG HHHHHHHCCCCEECC	41.43	21712546
93	Ubiquitination	LPEQLIKEAFILSDL CHHHHHHHHHHHHCC	41.64	33845483
94	Ubiquitination	PEQLIKEAFILSDLF HHHHHHHHHHHHCCC	7.56	23503661
135	Phosphorylation	GLVAVLLYWDGKRCI HHHHHHHHCCCHHHH	9.40	30631047
138	Ubiquitination	AVLLYWDGKRCIANS HHHHHCCCHHHHHHH	12.74	27667366
139	Sumoylation	VLLYWDGKRCIANSL HHHHCCCHHHHHHHH	41.44	-
147	Sumoylation	RCIANSLKALIQSRR HHHHHHHHHHHHCCC	40.75	-
147	Ubiquitination	RCIANSLKALIQSRR HHHHHHHHHHHHCCC	40.75	21963094
156	Ubiquitination	LIQSRRGKTWTLELS HHHCCCCCCEEEEEC	38.79	21890473
156	Ubiquitination	LIQSRRGKTWTLELS HHHCCCCCCEEEEEC	38.79	21963094
157	Phosphorylation	IQSRRGKTWTLELSP HHCCCCCCEEEEECH	26.89	30576142
163	Phosphorylation	KTWTLELSPELASMT CCEEEEECHHHHHCC	13.62	17192257
168	Phosphorylation	ELSPELASMTTRFTD EECHHHHHCCHHCCH	29.32	30576142
184	Phosphorylation	LMEQGLTYKVLTLVS HHHCCCHHHHHHHHH	12.25	30576142
188	Phosphorylation	GLTYKVLTLVSQIDV CCHHHHHHHHHHCCC	28.27	30622161
191	Phosphorylation	YKVLTLVSQIDVNNE HHHHHHHHHCCCCCH	25.24	30622161
201	Ubiquitination	DVNNEFEKLQRERGL CCCCHHHHHHHHCCC	56.06	29967540
212	2-Hydroxyisobutyrylation	ERGLGSEKHRKEVSD HCCCCCHHHHHHHHH	50.86	-
212	Ubiquitination	ERGLGSEKHRKEVSD HCCCCCHHHHHHHHH	50.86	-
213	Ubiquitination	RGLGSEKHRKEVSDL CCCCCHHHHHHHHHH	41.83	21890473
215	Ubiquitination	LGSEKHRKEVSDLIK CCCHHHHHHHHHHHH	63.29	24816145
218	Phosphorylation	EKHRKEVSDLIKECR HHHHHHHHHHHHHHH	27.99	20873877
222	Acetylation	KEVSDLIKECRQSLA HHHHHHHHHHHHHHH	59.04	26051181
222	Ubiquitination	KEVSDLIKECRQSLA HHHHHHHHHHHHHHH	59.04	-
285	Ubiquitination	CFDISFIEQSTEERD HHHHHHHCCCHHHCC	36.15	22817900
290	Ubiquitination	FIEQSTEERDDMIHQ HHCCCHHHCCHHHHH	62.59	21890473
304	Ubiquitination	QLPLLTEKQYIATIH HHHCCCCHHHHHHHH	43.07	21890473
304	Ubiquitination	QLPLLTEKQYIATIH HHHCCCCHHHHHHHH	43.07	23000965
321	Ubiquitination	LQDSQLWKLPGLQAT CCCHHHHCCCCHHHH	54.09	21890473
321	Ubiquitination	LQDSQLWKLPGLQAT CCCHHHHCCCCHHHH	54.09	23000965
328	Phosphorylation	KLPGLQATVRLAWAL CCCCHHHHHHHHHHH	8.00	20068231
434	Phosphorylation	MGNEPPISLRRDLEH CCCCCCCCHHHHHHH	22.92	-
450	Phosphorylation	MLLIGELYKKNPFHL HHHHHHHHHHCCCCH	18.67	-
451	Ubiquitination	LLIGELYKKNPFHLE HHHHHHHHHCCCCHH	59.71	33845483
452	Ubiquitination	LIGELYKKNPFHLEL HHHHHHHHCCCCHHH	57.19	23503661
495	Phosphorylation	PQRQVVLSKFVRQMG CHHHHHHHHHHHHHH	16.67	23909892
496	Ubiquitination	QRQVVLSKFVRQMGD HHHHHHHHHHHHHHH	43.66	21890473
496	Acetylation	QRQVVLSKFVRQMGD HHHHHHHHHHHHHHH	43.66	25953088
496	Ubiquitination	QRQVVLSKFVRQMGD HHHHHHHHHHHHHHH	43.66	27667366
532	Phosphorylation	QCAHYCFSLLKVNGS HHHHHHHHHEEECCC	29.27	24719451
533	Ubiquitination	CAHYCFSLLKVNGSS HHHHHHHHEEECCCC	2.41	24816145
534	Ubiquitination	AHYCFSLLKVNGSSH HHHHHHHEEECCCCC	5.88	33845483
560	Ubiquitination	VSWEHFFHSLMLYHE CCHHHHHHHHHHHHH	21.05	32015554
571	Ubiquitination	LYHEHLRKDLPSADS HHHHHHHHCCCCCCC	70.72	21890473
571	Ubiquitination	LYHEHLRKDLPSADS HHHHHHHHCCCCCCC	70.72	21906983
575	Phosphorylation	HLRKDLPSADSVQYR HHHHCCCCCCCCCEE	52.59	21945579
578	Phosphorylation	KDLPSADSVQYRHLP HCCCCCCCCCEECCC	15.73	21945579
581	Phosphorylation	PSADSVQYRHLPSRG CCCCCCCEECCCCCC	9.61	21945579
586	Phosphorylation	VQYRHLPSRGITQKE CCEECCCCCCCCHHH	49.88	29449344
617	Ubiquitination	WSENARLALCEHPQW ECCCCHHHHCCCCCC	12.47	24816145
643	Ubiquitination	CSIPPVLKAELLKTL CCCCHHHHHHHHHHH	39.80	22817900
648	Ubiquitination	VLKAELLKTLAAFGK HHHHHHHHHHHHHCC	54.86	21890473
648	Ubiquitination	VLKAELLKTLAAFGK HHHHHHHHHHHHHCC	54.86	22817900
649	Phosphorylation	LKAELLKTLAAFGKS HHHHHHHHHHHHCCC	22.92	-
655	Ubiquitination	KTLAAFGKSPEIAAS HHHHHHCCCHHHHHH	57.28	16196087
680	Phosphorylation	LQTVRIPSQRQAIGI HHHCCCCCHHHHEEE	35.31	24719451
684	Ubiquitination	RIPSQRQAIGIEVEL CCCCHHHHEEEEEEH	12.26	21963094
742	Phosphorylation	YLQFLRDSVFLRFRT HHHHHHHHHHHHHHH	14.34	20068231
792	Ubiquitination	DQFVELQGEEIIAYK HHHHHHCCCEEEEEC	47.32	21963094
807	Phosphorylation	PPGFSLMYHLLNESP CCCCHHHHHHHCCCH	8.46	32142685
819	Ubiquitination	ESPMLELALSLLEEG CCHHHHHHHHHHHHH	5.92	33845483
823	Ubiquitination	LELALSLLEEGVKQL HHHHHHHHHHHHHHC	5.17	22817900
833	Phosphorylation	GVKQLDTYAPFPGKK HHHHCCCCCCCCCHH	16.37	-
839	2-Hydroxyisobutyrylation	TYAPFPGKKHLEKAV CCCCCCCHHHHHHHH	36.94	-
839	Ubiquitination	TYAPFPGKKHLEKAV CCCCCCCHHHHHHHH	36.94	-
861	Ubiquitination	NLTLQKENLFMDLLR HHHHCCCCHHHHHHH	45.69	21963094
864	Sulfoxidation	LQKENLFMDLLRESQ HCCCCHHHHHHHHCH	3.90	21406390
890	Phosphorylation	LQGINPRTKKADNVV HCCCCCCCCCCCCHH	37.85	20860994
891	Ubiquitination	QGINPRTKKADNVVN CCCCCCCCCCCCHHC	47.44	24816145
892	Ubiquitination	GINPRTKKADNVVNI CCCCCCCCCCCHHCH	61.43	33845483
902	Phosphorylation	NVVNIARYLYHGNTN CHHCHHHHHHCCCCC	11.55	-
904	Phosphorylation	VNIARYLYHGNTNPE HCHHHHHHCCCCCHH	9.95	25599653
908	Phosphorylation	RYLYHGNTNPELAFE HHHHCCCCCHHHHHC	57.66	-
918	Ubiquitination	ELAFESAKILCCISC HHHHCCCCEEEEEEC	45.55	32015554
942	Phosphorylation	GDFTHDQSISQKLMA ECCCCCCHHHHHHHC	30.20	25159151
970	Phosphorylation	FVRLEEGSELEKKLV HHCCCCCCHHHHHHH	42.14	-
974	Ubiquitination	EEGSELEKKLVAIRH CCCCHHHHHHHHHHH	65.12	-
975	Ubiquitination	EGSELEKKLVAIRHE CCCHHHHHHHHHHHH	38.53	24816145
1013	Ubiquitination	LLGFELKKPVSTTNL HHHCEECCCCCCCCC	64.38	16196087
1016	Phosphorylation	FELKKPVSTTNLQDP CEECCCCCCCCCCCC	37.73	25693802
1017	Phosphorylation	ELKKPVSTTNLQDPG EECCCCCCCCCCCCC	21.67	25693802
1018	Phosphorylation	LKKPVSTTNLQDPGV ECCCCCCCCCCCCCC	26.82	25693802
1042	Acetylation	AILNILEKGTEGRTG HHHHHHHHCCCCCCC	68.63	26051181
1042	Ubiquitination	AILNILEKGTEGRTG HHHHHHHHCCCCCCC	68.63	21963094
1044	Phosphorylation	LNILEKGTEGRTGPV HHHHHHCCCCCCCCC	46.46	25367160
1048	Phosphorylation	EKGTEGRTGPVAVRE HHCCCCCCCCCCCCC	57.61	25367160
1103	Ubiquitination	QYLPFSNKEYEISML CCCCCCCCHHHHHHH	61.55	23000965
1105	Phosphorylation	LPFSNKEYEISMLNQ CCCCCCHHHHHHHHH	21.85	21406692
1108	Phosphorylation	SNKEYEISMLNQMSW CCCHHHHHHHHHHHH	12.79	21406692
1114	Phosphorylation	ISMLNQMSWLMKTAS HHHHHHHHHHHHHCC	13.80	21406692
1121	Phosphorylation	SWLMKTASIELRVTS HHHHHHCCCEEEHHH	23.10	22798277
1150	Acetylation	LLDDMPVKPYSDGEG HHCCCCCCCCCCCCC	32.16	26051181
1150	Ubiquitination	LLDDMPVKPYSDGEG HHCCCCCCCCCCCCC	32.16	21906983
1152	Phosphorylation	DDMPVKPYSDGEGGI CCCCCCCCCCCCCCC	17.42	30631047
1153	Phosphorylation	DMPVKPYSDGEGGIE CCCCCCCCCCCCCCC	47.90	25159151
1165	Phosphorylation	GIEDENRSVSGFLHF CCCCCCCCCCCCCCC	32.01	29255136
1167	Phosphorylation	EDENRSVSGFLHFDT CCCCCCCCCCCCCHH	25.69	30266825
1174	Phosphorylation	SGFLHFDTATKVRRK CCCCCCHHHHHHHHH	34.97	23927012
1176	Phosphorylation	FLHFDTATKVRRKIL CCCCHHHHHHHHHHH	31.97	23927012
1177	Ubiquitination	LHFDTATKVRRKILN CCCHHHHHHHHHHHH	31.14	21890473
1177	Ubiquitination	LHFDTATKVRRKILN CCCHHHHHHHHHHHH	31.14	22817900
1181	Ubiquitination	TATKVRRKILNILDS HHHHHHHHHHHHHHH	40.77	22817900
1190	Ubiquitination	LNILDSIDFSQEIPE HHHHHHCCCCCCCCC	40.89	20639865
1207	Ubiquitination	QLDFFDRAQIEQVIA CCCCCCHHHHHHHHH	19.29	23000965
1219	Ubiquitination	VIANCEHKNLRGQTV HHHHCCCCCCCCCCC	35.07	21890473
1219	Acetylation	VIANCEHKNLRGQTV HHHHCCCCCCCCCCC	35.07	26051181
1219	Ubiquitination	VIANCEHKNLRGQTV HHHHCCCCCCCCCCC	35.07	21906983
1225	Phosphorylation	HKNLRGQTVCNVKLL CCCCCCCCCCCHHHH	29.83	25159151
1230	Acetylation	GQTVCNVKLLHRVLV CCCCCCHHHHHHHHH	31.19	25953088
1230	Ubiquitination	GQTVCNVKLLHRVLV CCCCCCHHHHHHHHH	31.19	-
1271	2-Hydroxyisobutyrylation	QYVVGRNKLLQCLHA HHHHCCCHHHHHHHH	49.57	-
1271	Ubiquitination	QYVVGRNKLLQCLHA HHHHCCCHHHHHHHH	49.57	-
1279	2-Hydroxyisobutyrylation	LLQCLHAKRHALESW HHHHHHHHHHHHHHH	33.69	-
1279	Ubiquitination	LLQCLHAKRHALESW HHHHHHHHHHHHHHH	33.69	-
1373	Phosphorylation	HYAFMLDSCFTSPPP HHEEHHHHHCCCCCC	13.73	26074081
1374	Ubiquitination	YAFMLDSCFTSPPPE HEEHHHHHCCCCCCC	4.27	21890473
1376	Phosphorylation	FMLDSCFTSPPPEEN EHHHHHCCCCCCCCC	44.65	26074081
1377	Phosphorylation	MLDSCFTSPPPEENP HHHHHCCCCCCCCCC	18.37	26074081
1384	Ubiquitination	SPPPEENPLVGFASI CCCCCCCCCCCEEEC	31.53	33845483
1387	Ubiquitination	PEENPLVGFASIGDS CCCCCCCCEEECCCH	21.78	22817900
1388	Ubiquitination	EENPLVGFASIGDSS CCCCCCCEEECCCHH	3.62	22817900
1409	Ubiquitination	KLLDFILKTGGGFQR HHHHHHHHHCCCHHH	40.06	-
1446	Ubiquitination	DTLEAAKKTMWERLT CHHHHHHHHHHHHCC	38.60	-
1461	Ubiquitination	APEDVFSKLQRENIA CCHHHHHHHHHHCCH	36.86	21890473
1461	2-Hydroxyisobutyrylation	APEDVFSKLQRENIA CCHHHHHHHHHHCCH	36.86	-
1461	Ubiquitination	APEDVFSKLQRENIA CCHHHHHHHHHHCCH	36.86	23000965
1481	Ubiquitination	GAALMEVVCRDACDG HHHHHHHHHHHCCCC	1.09	29967540
1505	Phosphorylation	ALLDRIVSVDKQQQW HHHHHHCCCCHHHCH	23.40	22817900
1507	Ubiquitination	LDRIVSVDKQQQWLL HHHHCCCCHHHCHHH	35.22	29901268
1508	Acetylation	DRIVSVDKQQQWLLY HHHCCCCHHHCHHHH	48.10	26051181
1508	Ubiquitination	DRIVSVDKQQQWLLY HHHCCCCHHHCHHHH	48.10	-
1513	Ubiquitination	VDKQQQWLLYLSNSG CCHHHCHHHHHCCCC	1.64	21963094
1523	Ubiquitination	LSNSGYLKVLVDSLV HCCCCHHHHHHHHHC	25.66	22817900
1538	Phosphorylation	EDDRTLQSLLTPQPP CCCCHHHHHCCCCCC	28.58	22210691
1541	Phosphorylation	RTLQSLLTPQPPLLK CHHHHHCCCCCCHHH	25.77	22210691
1548	Ubiquitination	TPQPPLLKALYTYES CCCCCHHHHHHCHHH	43.99	22817900
1552	Phosphorylation	PLLKALYTYESKMAF CHHHHHHCHHHHHHH	22.97	30631047
1555	Phosphorylation	KALYTYESKMAFLTR HHHHCHHHHHHHHHH	19.81	22210691
1556	Ubiquitination	ALYTYESKMAFLTRV HHHCHHHHHHHHHHH	23.47	-
1561	Phosphorylation	ESKMAFLTRVAKIQQ HHHHHHHHHHHHHHH	19.35	30631047
1565	2-Hydroxyisobutyrylation	AFLTRVAKIQQGALE HHHHHHHHHHHHHHH	37.88	-
1565	Ubiquitination	AFLTRVAKIQQGALE HHHHHHHHHHHHHHH	37.88	23000965
1574	Ubiquitination	QQGALELLRSGVIVR HHHHHHHHHCCCEEE	2.75	27667366
1584	Phosphorylation	GVIVRLAQCQVYDMR CCEEEEEECEEEECC	23.83	32142685
1607	Sulfoxidation	FGMRDPPMFIPTPVD CCCCCCCCCCCCCHH	6.06	21406390
1619	Ubiquitination	PVDRYRQILLPALQL CHHHHHHHHHHHHHH	2.93	21963094
1620	Ubiquitination	VDRYRQILLPALQLC HHHHHHHHHHHHHHH	3.38	22817900
1630	Ubiquitination	ALQLCQVILTSSMAQ HHHHHHHHHCHHHHH	1.11	23000965
1662	Glutathionylation	TIQAILRCQDVSAGS HHHHHHCCCCCCCCC	3.48	22555962
1666	Phosphorylation	ILRCQDVSAGSLQEL HHCCCCCCCCCHHHH	34.89	20071362
1669	Phosphorylation	CQDVSAGSLQELALL CCCCCCCCHHHHHHH	26.96	20071362
1677	Phosphorylation	LQELALLTGIISKAA HHHHHHHHHHHHHHH	27.47	20071362
1681	Phosphorylation	ALLTGIISKAALPGI HHHHHHHHHHHCCCH	17.83	24719451
1732	Ubiquitination	SDRLRQFKFQDDNVE CHHHHCCCCCCCCCC	33.50	21890473
1732	Ubiquitination	SDRLRQFKFQDDNVE CHHHHCCCCCCCCCC	33.50	27667366
1742	Acetylation	DDNVEGDKVSKKDEI CCCCCCCCCCHHHHH	60.30	26051181
1742	Ubiquitination	DDNVEGDKVSKKDEI CCCCCCCCCCHHHHH	60.30	21906983
1745	Ubiquitination	VEGDKVSKKDEIELA CCCCCCCHHHHHHHH	68.20	22817900
1746	Ubiquitination	EGDKVSKKDEIELAM CCCCCCHHHHHHHHH	53.76	22817900
1799	Phosphorylation	RDGPRQDTQAPVVPY CCCCCCCCCCCCCCC	20.49	20068231
1806	Phosphorylation	TQAPVVPYWRLPGLG CCCCCCCCCCCCCHH	7.49	20068231
1839	Ubiquitination	SHRQSVSKLQNVEQL HHHHHHHHHCCHHHC	52.52	29967540
1852	Acetylation	QLPPDEIKELCQSVM HCCHHHHHHHHHHHC	42.45	26051181
1865	Acetylation	VMPAGVDKISTAQKY HCCCCCCCHHHHHHH	35.83	26051181
1865	Ubiquitination	VMPAGVDKISTAQKY HCCCCCCCHHHHHHH	35.83	29901268
1868	Phosphorylation	AGVDKISTAQKYVLA CCCCCHHHHHHHHHH	36.26	22817900
1871	Acetylation	DKISTAQKYVLARRR CCHHHHHHHHHHHHH	34.56	25038526
1871	Ubiquitination	DKISTAQKYVLARRR CCHHHHHHHHHHHHH	34.56	21963094
1881	Acetylation	LARRRLVKVINNRAK HHHHHHHHHHCCHHH	41.82	26051181
1881	Ubiquitination	LARRRLVKVINNRAK HHHHHHHHHHCCHHH	41.82	21906983
1932	Methylation	FASRTLFKSRRLQDS HHHHHHHHHCHHHHC	46.28	-
1932	Ubiquitination	FASRTLFKSRRLQDS HHHHHHHHHCHHHHC	46.28	27667366
1933	Phosphorylation	ASRTLFKSRRLQDSF HHHHHHHHCHHHHCC	18.46	24719451
1939	Phosphorylation	KSRRLQDSFASETNL HHCHHHHCCCCCCCC	15.11	25159151
1942	Phosphorylation	RLQDSFASETNLDFR HHHHCCCCCCCCCCC	42.83	29255136
1944	Phosphorylation	QDSFASETNLDFRSG HHCCCCCCCCCCCCC	38.29	30266825
1977	Ubiquitination	AFGESLQKKLLDIEG HHHHHHHHHHHCHHH	51.16	21906983
1978	Ubiquitination	FGESLQKKLLDIEGL HHHHHHHHHHCHHHH	41.12	22817900
1986	Phosphorylation	LLDIEGLYSKVRSRY HHCHHHHHHHHHHHH	19.80	20068231
1987	Phosphorylation	LDIEGLYSKVRSRYS HCHHHHHHHHHHHHH	29.71	21406692
1988	Ubiquitination	DIEGLYSKVRSRYSF CHHHHHHHHHHHHHH	28.27	21890473
1988	2-Hydroxyisobutyrylation	DIEGLYSKVRSRYSF CHHHHHHHHHHHHHH	28.27	-
1988	Acetylation	DIEGLYSKVRSRYSF CHHHHHHHHHHHHHH	28.27	25953088
1988	Ubiquitination	DIEGLYSKVRSRYSF CHHHHHHHHHHHHHH	28.27	23000965

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NU205_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NU205_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
1377	Phosphorylation	1383 (6)	N ⇒ K	rs150498874	Venous thromboembolism adjusted for sickle cell variant rs77121243-T	28203683

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TADA3_HUMAN	TADA3	physical	22939629
NUDC3_HUMAN	NUDCD3	physical	22863883
STOM_HUMAN	STOM	physical	27173435

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NU205_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, AND MASS SPECTROMETRY.	19413330 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1939 AND SER-1942, ANDMASS SPECTROMETRY.	19690332 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-3 AND SER-1939, AND MASSSPECTROMETRY.	18691976 [Abstract]
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis."; Wang B., Malik R., Nigg E.A., Korner R.; Anal. Chem. 80:9526-9533(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1165, AND MASSSPECTROMETRY.	19007248 [Abstract]