RASF9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RASF9_HUMAN
• UniProt AC: O75901
• Protein Name: Ras association domain-containing protein 9
• Gene Name: RASSF9
• Organism: Homo sapiens (Human).
• Sequence Length: 435
• Subcellular Localization: Endosome. Accumulates on perinuclear endosomes..
• Protein Description: May play a role in regulating vesicuar trafficking in cells..
• Protein Sequence: MAPFGRNLLKTRHKNRSPTKDMDSEEKEIVVWVCQEEKLVCGLTKRTTSADVIQALLEEHEATFGEKRFLLGKPSDYCIIEKWRGSERVLPPLTRILKLWKAWGDEQPNMQFVLVKADAFLPVPLWRTAEAKLVQNTEKLWELSPANYMKTLPPDKQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINEDAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELLAKEFNSLHISNKDGCQLKENRAKESEVPSSNGEIPPFTQRVFSNYTNDTDSDTGISSNHSQDSETTVGDVVLLST

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	KTRHKNRSPTKDMDS HHCCCCCCCCCCCCH	46.44	26329039
45	Ubiquitination	KLVCGLTKRTTSADV CCCCCCCCCCCHHHH	53.44	29967540
67	Ubiquitination	HEATFGEKRFLLGKP HHCHHCCCCHHCCCC	49.15	29967540
77	Phosphorylation	LLGKPSDYCIIEKWR HCCCCCCCEEEECCC	7.01	22461510
132	Ubiquitination	LWRTAEAKLVQNTEK HHHCHHHHHHHCHHH	40.47	29967540
184	Ubiquitination	SHDRDNMETLVHLII CCCCCCHHHHHHHHH	45.29	22053931
205	Ubiquitination	HQQVKRMKELDLEIE HHHHHHHHHHCHHHH	60.19	22053931
317	Phosphorylation	LESSNLESVKCDLEK HHHCCCCCCCCCHHH	30.00	26074081
325	Phosphorylation	VKCDLEKSMKAGLKI CCCCHHHHHHHCHHH	19.01	26074081
334	Phosphorylation	KAGLKIHSHLSGIQK HHCHHHHHHHHHHHH	29.60	26074081
337	Phosphorylation	LKIHSHLSGIQKEIK HHHHHHHHHHHHHHC	28.55	26074081
345	Phosphorylation	GIQKEIKYSDSLLQM HHHHHHCCCHHHHHH	24.30	26074081
346	Phosphorylation	IQKEIKYSDSLLQMK HHHHHCCCHHHHHHH	18.74	26074081
348	Phosphorylation	KEIKYSDSLLQMKAK HHHCCCHHHHHHHHH	25.66	26074081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RASF9_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RASF9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RASF9_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ASPP1_HUMAN	PPP1R13B	physical	24366813
ASPP2_HUMAN	TP53BP2	physical	24366813
CATD_HUMAN	CTSD	physical	24366813
CC85B_HUMAN	CCDC85B	physical	24366813
CC85C_HUMAN	CCDC85C	physical	24366813
CSK2B_HUMAN	CSNK2B	physical	24366813
CYTA_HUMAN	CSTA	physical	24366813
DDB1_HUMAN	DDB1	physical	24366813
DVL1_HUMAN	DVL1	physical	24366813
DVL2_HUMAN	DVL2	physical	24366813
DVL3_HUMAN	DVL3	physical	24366813
G3BP1_HUMAN	G3BP1	physical	24366813
GGCT_HUMAN	GGCT	physical	24366813
KCMF1_HUMAN	KCMF1	physical	24366813
PARD3_HUMAN	PARD3	physical	24366813
PCBP1_HUMAN	PCBP1	physical	24366813
PP1A_HUMAN	PPP1CA	physical	24366813
PP1B_HUMAN	PPP1CB	physical	24366813
PP1G_HUMAN	PPP1CC	physical	24366813
PRIC3_HUMAN	PRICKLE3	physical	24366813
PTOV1_HUMAN	PTOV1	physical	24366813
RASF7_HUMAN	RASSF7	physical	24366813
RBBP4_HUMAN	RBBP4	physical	24366813
S10A7_HUMAN	S100A7	physical	24366813
SAPC2_HUMAN	SAPCD2	physical	24366813
SPB3_HUMAN	SERPINB3	physical	24366813
SPB4_HUMAN	SERPINB4	physical	24366813
SPR2E_HUMAN	SPRR2E	physical	24366813
TCOF_HUMAN	TCOF1	physical	24366813
VANG1_HUMAN	VANGL1	physical	24366813
ZA2G_HUMAN	AZGP1	physical	24366813

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.