CC85B_HUMAN - dbPTM
CC85B_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CC85B_HUMAN
UniProt AC Q15834
Protein Name Coiled-coil domain-containing protein 85B
Gene Name CCDC85B
Organism Homo sapiens (Human).
Sequence Length 202
Subcellular Localization Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
Protein Description Functions as a transcriptional repressor. [PubMed: 17014843 May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth]
Protein Sequence MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQEELLRENLALKELCLALGEEWGPRGGPSGAGGSGAGPAPELALPPCGPRDLGDGSSSTGSVGSPDQLPLACSPDD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
1Acetylation-------MEAEAGGL
-------CCCCCCCH		11.2622814378
119UbiquitinationDLGGCWQKLAELEGR
HHCHHHHHHHHHCCH		25.7630230243
138UbiquitinationLRENLALKELCLALG
HHHHHHHHHHHHHHC		42.9330230243
184PhosphorylationDLGDGSSSTGSVGSP
CCCCCCCCCCCCCCC		38.1825627689
185PhosphorylationLGDGSSSTGSVGSPD
CCCCCCCCCCCCCCH		35.1125627689
187PhosphorylationDGSSSTGSVGSPDQL
CCCCCCCCCCCCHHC		24.3228985074
190PhosphorylationSSTGSVGSPDQLPLA
CCCCCCCCCHHCCCC		24.1328985074
199PhosphorylationDQLPLACSPDD----
HHCCCCCCCCC----		26.2528985074
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CC85B_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CC85B_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CC85B_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ZN250_HUMANZNF250physical
16189514
KANL1_HUMANKANSL1physical
16189514
PBIP1_HUMANPBXIP1physical
16189514
ZN821_HUMANZNF821physical
16189514
NIF3L_HUMANNIF3L1physical
16189514
ZN337_HUMANZNF337physical
16189514
C2CD6_HUMANALS2CR11physical
16189514
BEX3_HUMANNGFRAP1physical
16189514
TEANC_HUMANTCEANCphysical
16189514
TSYL4_HUMANTSPYL4physical
16189514
CFA53_HUMANCFAP53physical
16189514
GCP4_HUMANTUBGCP4physical
16189514
K1C20_HUMANKRT20physical
16189514
CSN4_HUMANCOPS4physical
16189514
FBF1_HUMANFBF1physical
16189514
THAP7_HUMANTHAP7physical
16189514
EAF6_HUMANMEAF6physical
16189514
ZN417_HUMANZNF417physical
16189514
CC112_HUMANCCDC112physical
16189514
BEX2_HUMANBEX2physical
16189514
MIC19_HUMANCHCHD3physical
16189514
SYT17_HUMANSYT17physical
16189514
ZN426_HUMANZNF426physical
16189514
F214B_HUMANFAM214Bphysical
16189514
F208B_HUMANFAM208Bphysical
16189514
CCD33_HUMANCCDC33physical
16189514
LNX1_HUMANLNX1physical
16189514
CWC25_HUMANCWC25physical
16189514
LZTS2_HUMANLZTS2physical
16189514
IKZF5_HUMANIKZF5physical
16189514
CC185_HUMANCCDC185physical
16189514
SETD5_HUMANSETD5physical
16189514
FA50B_HUMANFAM50Bphysical
16189514
SYTL4_HUMANSYTL4physical
16189514
MOAP1_HUMANMOAP1physical
16189514
FAKD5_HUMANFASTKD5physical
16189514
RBM41_HUMANRBM41physical
16189514
CC120_HUMANCCDC120physical
16189514
DEPP_HUMANC10orf10physical
16189514
AKIR2_HUMANAKIRIN2physical
16189514
AGGF1_HUMANAGGF1physical
16189514
MCM10_HUMANMCM10physical
16189514
CC116_HUMANCCDC116physical
16189514
TCHP_HUMANTCHPphysical
16189514
DEUP1_HUMANCCDC67physical
16189514
DOK5_HUMANDOK5physical
16189514
LMO3_HUMANLMO3physical
16189514
MBIP1_HUMANMBIPphysical
16189514
RIBC2_HUMANRIBC2physical
16189514
EXOC7_HUMANEXOC7physical
16189514
ZN638_HUMANZNF638physical
16189514
CS025_HUMANC19orf25physical
16189514
GCC1_HUMANGCC1physical
16189514
RALYL_HUMANRALYLphysical
16189514
TTC14_HUMANTTC14physical
16189514
SCNM1_HUMANSCNM1physical
16189514
DS13A_HUMANDUSP13physical
16189514
DS13B_HUMANDUSP13physical
16189514
SPT46_HUMANC1orf111physical
16189514
EXOC8_HUMANEXOC8physical
16189514
ENKD1_HUMANENKD1physical
16189514
CEP70_HUMANCEP70physical
16189514
APEX2_HUMANAPEX2physical
16189514
LDOC1_HUMANLDOC1physical
16189514
PKHF2_HUMANPLEKHF2physical
16189514
FA13C_HUMANFAM13Cphysical
16189514
CARD9_HUMANCARD9physical
16189514
F107A_HUMANFAM107Aphysical
16189514
ZC21C_HUMANZC2HC1Cphysical
16189514
ZN764_HUMANZNF764physical
16189514
CG050_HUMANC7orf50physical
16189514
MOB1A_HUMANMOB1Aphysical
16189514
PIDD1_HUMANPIDD1physical
16189514
FND11_HUMANC20orf195physical
16189514
EURL_HUMANC21orf91physical
16189514
PHOCN_HUMANMOB4physical
16189514
CH048_HUMANC8orf48physical
16189514
ZC3H1_HUMANZFC3H1physical
16189514
F124B_HUMANFAM124Bphysical
16189514
UTP6_HUMANUTP6physical
16189514
NUP54_HUMANNUP54physical
16189514
MCRS1_HUMANMCRS1physical
17014843
TTC25_HUMANTTC25physical
25416956
ZN564_HUMANZNF564physical
25416956
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CC85B_HUMAN

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Related Literatures of Post-Translational Modification

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