ZN764_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN764_HUMAN
• UniProt AC: Q96H86
• Protein Name: Zinc finger protein 764
• Gene Name: ZNF764
• Organism: Homo sapiens (Human).
• Sequence Length: 408
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAPPLAPLPPRDPNGAGPEWREPGAVSFADVAVYFCREEWGCLRPAQRALYRDVMRETYGHLSALGIGGNKPALISWVEEEAELWGPAAQDPEVAKCQTQTDPADSRNKKKERQREGTGALEKPDPVAAGSPGLKSPQAPSAGPPYGWEQLSKAPHRGRPSLCAHPPVPRADQRHGCYVCGKSFAWRSTLVEHVYSHTGEKPFHCTDCGKGFGHASSLSKHRAIHRGERPHRCLECGRAFTQRSALTSHLRVHTGEKPYGCADCGRRFSQSSALYQHRRVHSGETPFPCPDCGRAFAYPSDLRRHVRTHTGEKPYPCPDCGRCFRQSSEMAAHRRTHSGEKPYPCPQCGRRFGQKSAVAKHQWVHRPGAGGHRGRVAGRLSVTLTPGHGDLDPPVGFQLYPEIFQECG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
118	Phosphorylation	KERQREGTGALEKPD HHHHHHCCCCCCCCC	17.96	23312004
131	Phosphorylation	PDPVAAGSPGLKSPQ CCCCCCCCCCCCCCC	15.86	23401153
136	Phosphorylation	AGSPGLKSPQAPSAG CCCCCCCCCCCCCCC	27.56	25159151
216	Phosphorylation	GKGFGHASSLSKHRA CCCCCCCHHHHHCCH	26.57	25159151
217	Phosphorylation	KGFGHASSLSKHRAI CCCCCCHHHHHCCHH	37.13	28555341
254	Phosphorylation	TSHLRVHTGEKPYGC HHCEEEECCCCCCCC	44.15	29214152
269	Phosphorylation	ADCGRRFSQSSALYQ CCCCCCCCCCHHHHH	27.60	28555341
272	Phosphorylation	GRRFSQSSALYQHRR CCCCCCCHHHHHCCC	18.04	19413330
282	Phosphorylation	YQHRRVHSGETPFPC HHCCCCCCCCCCCCC	35.15	28555341
308	Phosphorylation	DLRRHVRTHTGEKPY HHHHHHHHCCCCCCC	23.77	-
310	Phosphorylation	RRHVRTHTGEKPYPC HHHHHHCCCCCCCCC	46.56	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN764_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN764_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN764_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SPD2A_HUMAN	SH3PXD2A	physical	28514442
NEBL_HUMAN	NEBL	physical	28514442
SUFU_HUMAN	SUFU	physical	28514442
SPD2B_HUMAN	SH3PXD2B	physical	28514442
TRI39_HUMAN	TRIM39	physical	28514442
UBP34_HUMAN	USP34	physical	28514442
GLCNE_HUMAN	GNE	physical	28514442
SMRCD_HUMAN	SMARCAD1	physical	28514442
TIF1B_HUMAN	TRIM28	physical	28514442
MYO1E_HUMAN	MYO1E	physical	28514442
RS27A_HUMAN	RPS27A	physical	28514442
LASP1_HUMAN	LASP1	physical	28514442
TRI41_HUMAN	TRIM41	physical	28514442
ERBIN_HUMAN	ERBB2IP	physical	28514442
SH3K1_HUMAN	SH3KBP1	physical	28514442
TIF1A_HUMAN	TRIM24	physical	28514442
SNX18_HUMAN	SNX18	physical	28514442
ZN316_HUMAN	ZNF316	physical	28514442
TF3C2_HUMAN	GTF3C2	physical	28514442
PP2AA_HUMAN	PPP2CA	physical	28514442
CBX5_HUMAN	CBX5	physical	28514442
OBSL1_HUMAN	OBSL1	physical	28514442
TF3C3_HUMAN	GTF3C3	physical	28514442
TRI27_HUMAN	TRIM27	physical	28514442
CP24A_HUMAN	CYP24A1	physical	28514442
MDM2_HUMAN	MDM2	physical	28514442
TF3C1_HUMAN	GTF3C1	physical	28514442
TRAF7_HUMAN	TRAF7	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-131, AND MASSSPECTROMETRY.
PubMed: 19413330