dbPTM

SPD2A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SPD2A_HUMAN	Jmol._Canvas2D (Jmol) "myJmol"[x]
UniProt AC	Q5TCZ1
Protein Name	SH3 and PX domain-containing protein 2A
Gene Name	SH3PXD2A
Organism	Homo sapiens (Human).
Sequence Length	1133
Subcellular Localization	Cytoplasm. Cell projection, podosome. Cytoplasmic in normal cells and localizes to podosomes in SRC-transformed cells.
Protein Description	Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide..
Protein Sequence	MLAYCVQDATVVDVEKRRNPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRFFEARPEDVNPPKEDYGSSKRKSVWLSSWAESPKKDVTGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEVSKRRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKKNLAGPVEIIGNIMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLAQGSPAVARIAPQRAQISSPNLRTRPPPRRESSLGFQLPKPPEPPSVEVEYYTIAEFQSCISDGISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASYIDKRKKPNLSRRTSTLTRPKVPPPAPPSKPKEAEEGPTGASESQDSPRKLKYEEPEYDIPAFGFDSEPELSEEPVEDRASGERRPAQPHRPSPASSLQRARFKVGESSEDVALEEETIYENEGFRPYAEDTLSARGSSGDSDSPGSSSLSLTRKNSPKSGSPKSSSLLKLKAEKNAQAEMGKNHSSASFSSSITINTTCCSSSSSSSSSLSKTSGDLKPRSASDAGIRGTPKVRAKKDADANAGLTSCPRAKPSVRPKPFLNRAESQSQEKMDISTLRRQLRPTGQLRGGLKGSKSEDSELPPQTASEAPSEGSRRSSSDLITLPATTPPCPTKKEWEGPATSYMTCSAYQKVQDSEISFPAGVEVQVLEKQESGWWYVRFGELEGWAPSHYLVLDENEQPDPSGKELDTVPAKGRQNEGKSDSLEKIERRVQALNTVNQSKKATPPIPSKPPGGFGKTSGTPAVKMRNGVRQVAVRPQSVFVSPPPKDNNLSCALRRNESLTATDGLRGVRRNSSFSTARSAAAEAKGRLAERAASQGSDSPLLPAQRNSIPVSPVRPKPIEKSQFIHNNLKDVYVSIADYEGDEETAGFQEGVSMEVLERNPNGWWYCQILDGVKPFKGWVPSNYLEKKN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MLAYCVQDATV ----CCEEEECCCEE	13.04	23663014
10	Phosphorylation	AYCVQDATVVDVEKR EEEECCCEEEEHHHH	29.38	23663014
78	Ubiquitination	IIPFLPGKILFRRSH EECCCCCCEEEECHH	34.01	21890473
78 (in isoform 1)	Ubiquitination	-	34.01	21890473
84	Phosphorylation	GKILFRRSHIRDVAV CCEEEECHHHHHHHH	21.00	24719451
84 (in isoform 3)	Phosphorylation	-	21.00	24719451
89 (in isoform 2)	Ubiquitination	-	4.78	21906983
135	Phosphorylation	VNPPKEDYGSSKRKS CCCCHHHCCCCCCCE	21.72	26074081
137	Phosphorylation	PPKEDYGSSKRKSVW CCHHHCCCCCCCEEE	26.85	26074081
138	Phosphorylation	PKEDYGSSKRKSVWL CHHHCCCCCCCEEEE	31.92	26074081
142	Phosphorylation	YGSSKRKSVWLSSWA CCCCCCCEEEECCCC	23.66	30301811
146	Phosphorylation	KRKSVWLSSWAESPK CCCEEEECCCCCCCC	14.23	30301811
147	Phosphorylation	RKSVWLSSWAESPKK CCEEEECCCCCCCCC	28.30	30301811
151	Phosphorylation	WLSSWAESPKKDVTG EECCCCCCCCCCCCC	33.98	27732954
183	Phosphorylation	NYKKQENSELSLQAG CCCCCCCCEEEEECC	38.88	30266825
186	Phosphorylation	KQENSELSLQAGEVV CCCCCEEEEECCCEE	17.87	30266825
236	Ubiquitination	DSDINTSKTGEVSKR CCCCCCCCCCCHHHH	59.52	-
256	Phosphorylation	RRLDRRWTLGGMVNR HHHHHHCHHHHCCCC	17.45	22617229
266	Phosphorylation	GMVNRQHSREEKYVT HCCCCCCCCCCCEEE	32.80	28270605
271	Phosphorylation	QHSREEKYVTVQPYT CCCCCCCEEEEECCC	12.48	29496907
273	Phosphorylation	SREEKYVTVQPYTSQ CCCCCEEEEECCCCC	15.44	28270605
278	Phosphorylation	YVTVQPYTSQSKDEI EEEEECCCCCCCHHH	27.29	29496907
282	Ubiquitination	QPYTSQSKDEIGFEK ECCCCCCCHHHCCCC	52.31	2190698
282 (in isoform 1)	Ubiquitination	-	52.31	21890473
305	Phosphorylation	KNLEGWWYIRYLGKE HHCCCEEEEEECCCC	2.96	22817900
308	Phosphorylation	EGWWYIRYLGKEGWA CCEEEEEECCCCCCC	15.39	22817900
319	Phosphorylation	EGWAPASYLKKAKDD CCCCCHHHHHHHHHC	25.33	22817900
348	Phosphorylation	IGNIMEISNLLNKKA HHHHHHHHHHHCHHC	14.23	22210691
351 (in isoform 3)	Phosphorylation	-	11.76	27251275
356	Phosphorylation	NLLNKKASGDKETPP HHHCHHCCCCCCCCC	57.30	23312004
361	Phosphorylation	KASGDKETPPAEGEG HCCCCCCCCCCCCCC	40.07	23312004
378	Phosphorylation	APIAKKEISLPILCN CCCCCCEECCCEEEE	7.61	19007248
378 (in isoform 3)	Phosphorylation	-	7.61	24719451
379	Phosphorylation	PIAKKEISLPILCNA CCCCCEECCCEEEEC	29.23	26657352
387	Phosphorylation	LPILCNASNGSAVGV CCEEEECCCCCCCCC	27.94	27251275
392 (in isoform 3)	Phosphorylation	-	9.46	24719451
393	Phosphorylation	ASNGSAVGVPDRTVS CCCCCCCCCCHHHHH	25.59	19664994
393 (in isoform 3)	Phosphorylation	-	25.59	27251275
406	Phosphorylation	VSRLAQGSPAVARIA HHHHHCCCHHHHHHC	9.52	29255136
420	Phosphorylation	APQRAQISSPNLRTR CCCCCCCCCCCCCCC	27.88	30266825
421	Phosphorylation	PQRAQISSPNLRTRP CCCCCCCCCCCCCCC	21.31	19664994
434	Phosphorylation	RPPPRRESSLGFQLP CCCCCCCCCCCCCCC	29.11	22468782
440	Phosphorylation	ESSLGFQLPKPPEPP CCCCCCCCCCCCCCC	5.71	20058876
453	Phosphorylation	PPSVEVEYYTIAEFQ CCCEEEEEEEHHHHH	15.87	-
468	Phosphorylation	SCISDGISFRGGQKA HHHCCCCCCCCCCEE	17.89	20058876
488 (in isoform 3)	Phosphorylation	-	1.78	27251275
514	Phosphorylation	KPNLSRRTSTLTRPK CCCCCCCCCCCCCCC	25.59	30266825
515	Phosphorylation	PNLSRRTSTLTRPKV CCCCCCCCCCCCCCC	21.43	30266825
516	Phosphorylation	NLSRRTSTLTRPKVP CCCCCCCCCCCCCCC	31.38	30266825
518	Phosphorylation	SRRTSTLTRPKVPPP CCCCCCCCCCCCCCC	45.04	30266825
519	Phosphorylation	RRTSTLTRPKVPPPA CCCCCCCCCCCCCCC	31.96	20068231
519 (in isoform 3)	Phosphorylation	-	31.96	24719451
539	Phosphorylation	KEAEEGPTGASESQD CCCCCCCCCCCCCCC	57.12	23927012
539 (in isoform 3)	Phosphorylation	-	57.12	24719451
542	Phosphorylation	EEGPTGASESQDSPR CCCCCCCCCCCCCCC	38.84	30266825
544	Phosphorylation	GPTGASESQDSPRKL CCCCCCCCCCCCCCC	36.47	30266825
547	Phosphorylation	GASESQDSPRKLKYE CCCCCCCCCCCCCCC	20.97	29255136
553	Phosphorylation	DSPRKLKYEEPEYDI CCCCCCCCCCCCCCC	35.64	28796482
558	Phosphorylation	LKYEEPEYDIPAFGF CCCCCCCCCCCCCCC	29.86	28796482
565	Phosphorylation	YDIPAFGFDSEPELS CCCCCCCCCCCCCCC	8.25	18669648
565 (in isoform 3)	Phosphorylation	-	8.25	24719451
567	Phosphorylation	IPAFGFDSEPELSEE CCCCCCCCCCCCCCC	53.44	28176443
568	Phosphorylation	PAFGFDSEPELSEEP CCCCCCCCCCCCCCC	44.64	17081983
568 (in isoform 3)	Phosphorylation	-	44.64	24719451
569	Phosphorylation	AFGFDSEPELSEEPV CCCCCCCCCCCCCCC	52.35	17081983
569 (in isoform 3)	Phosphorylation	-	52.35	24719451
572	Phosphorylation	FDSEPELSEEPVEDR CCCCCCCCCCCCCCC	37.95	28796482
580 (in isoform 3)	Phosphorylation	-	33.92	27251275
581	Phosphorylation	EPVEDRASGERRPAQ CCCCCCCCCCCCCCC	41.92	27642862
593	Phosphorylation	PAQPHRPSPASSLQR CCCCCCCCCHHHHHH	32.81	30266825
596	Phosphorylation	PHRPSPASSLQRARF CCCCCCHHHHHHHHE	34.66	30266825
597	Phosphorylation	HRPSPASSLQRARFK CCCCCHHHHHHHHEE	30.54	30266825
608	Phosphorylation	ARFKVGESSEDVALE HHEECCCCCHHCCCC	32.85	30576142
609	Phosphorylation	RFKVGESSEDVALEE HEECCCCCHHCCCCE	33.25	23090842
616	Phosphorylation	SEDVALEEETIYENE CHHCCCCEEEEECCC	62.38	20068231
616 (in isoform 3)	Phosphorylation	-	62.38	24719451
620	Phosphorylation	ALEEETIYENEGFRP CCCEEEEECCCCCCC	21.81	27642862
620 (in isoform 3)	Phosphorylation	-	21.81	27251275
621 (in isoform 3)	Phosphorylation	-	44.98	24719451
632	Phosphorylation	FRPYAEDTLSARGSS CCCCCCCCCCCCCCC	17.70	27642862
634	Phosphorylation	PYAEDTLSARGSSGD CCCCCCCCCCCCCCC	20.29	27642862
634 (in isoform 3)	Phosphorylation	-	20.29	24719451
638	Phosphorylation	DTLSARGSSGDSDSP CCCCCCCCCCCCCCC	26.12	30576142
639	Phosphorylation	TLSARGSSGDSDSPG CCCCCCCCCCCCCCC	49.82	30576142
639 (in isoform 3)	Phosphorylation	-	49.82	24719451
642	Phosphorylation	ARGSSGDSDSPGSSS CCCCCCCCCCCCCCC	43.44	30266825
644	Phosphorylation	GSSGDSDSPGSSSLS CCCCCCCCCCCCCCE	34.80	30266825
647	Phosphorylation	GDSDSPGSSSLSLTR CCCCCCCCCCCEEEC	21.82	30266825
648	Phosphorylation	DSDSPGSSSLSLTRK CCCCCCCCCCEEECC	41.01	30266825
649	Phosphorylation	SDSPGSSSLSLTRKN CCCCCCCCCEEECCC	24.55	30266825
651	Phosphorylation	SPGSSSLSLTRKNSP CCCCCCCEEECCCCC	29.64	30266825
653	Phosphorylation	GSSSLSLTRKNSPKS CCCCCEEECCCCCCC	35.90	30266825
657	Phosphorylation	LSLTRKNSPKSGSPK CEEECCCCCCCCCCC	36.42	27134283
660	Phosphorylation	TRKNSPKSGSPKSSS ECCCCCCCCCCCCHH	48.14	23532336
662	Phosphorylation	KNSPKSGSPKSSSLL CCCCCCCCCCCHHHH	35.92	23312004
665	Phosphorylation	PKSGSPKSSSLLKLK CCCCCCCCHHHHHHH	28.66	23312004
666	Phosphorylation	KSGSPKSSSLLKLKA CCCCCCCHHHHHHHH	31.00	20166139
667	Phosphorylation	SGSPKSSSLLKLKAE CCCCCCHHHHHHHHH	44.82	24719451
696	Phosphorylation	SFSSSITINTTCCSS CCCCCEEEECEECCC	4.04	18669648
696 (in isoform 3)	Phosphorylation	-	4.04	24719451
703	Phosphorylation	INTTCCSSSSSSSSS EECEECCCCCCCCCC	21.96	18669648
703 (in isoform 3)	Phosphorylation	-	21.96	24719451
704	Phosphorylation	NTTCCSSSSSSSSSL ECEECCCCCCCCCCC	20.25	-
705	Phosphorylation	TTCCSSSSSSSSSLS CEECCCCCCCCCCCC	35.87	-
706	Phosphorylation	TCCSSSSSSSSSLSK EECCCCCCCCCCCCC	35.87	-
707	Phosphorylation	CCSSSSSSSSSLSKT ECCCCCCCCCCCCCC	35.87	-
722	Phosphorylation	SGDLKPRSASDAGIR CCCCCCCCHHHCCCC	40.42	21815630
724	Phosphorylation	DLKPRSASDAGIRGT CCCCCCHHHCCCCCC	29.28	29255136
731	Phosphorylation	SDAGIRGTPKVRAKK HHCCCCCCCCCCCCC	15.30	26055452
739	Phosphorylation	PKVRAKKDADANAGL CCCCCCCCCCCCCCC	49.31	20068231
739 (in isoform 3)	Phosphorylation	-	49.31	24719451
741	Phosphorylation	VRAKKDADANAGLTS CCCCCCCCCCCCCCC	50.95	17525332
741 (in isoform 3)	Phosphorylation	-	50.95	24719451
747	O-linked_Glycosylation	ADANAGLTSCPRAKP CCCCCCCCCCCCCCC	27.62	29237092
748	Phosphorylation	DANAGLTSCPRAKPS CCCCCCCCCCCCCCC	27.45	30576142
767	Phosphorylation	PFLNRAESQSQEKMD HHCCHHHHHCHHHCC	33.86	30576142
769	Phosphorylation	LNRAESQSQEKMDIS CCHHHHHCHHHCCHH	49.97	17525332
769 (in isoform 3)	Phosphorylation	-	49.97	24719451
776	Phosphorylation	SQEKMDISTLRRQLR CHHHCCHHHHHHHHC	19.68	20068231
777	Phosphorylation	QEKMDISTLRRQLRP HHHCCHHHHHHHHCC	25.31	20068231
785	Phosphorylation	LRRQLRPTGQLRGGL HHHHHCCCCCCCCCC	31.00	-
789	Methylation	LRPTGQLRGGLKGSK HCCCCCCCCCCCCCC	29.28	18958349
792 (in isoform 3)	Phosphorylation	-	6.72	24719451
795	Phosphorylation	LRGGLKGSKSEDSEL CCCCCCCCCCCCCCC	31.27	23401153
797	Phosphorylation	GGLKGSKSEDSELPP CCCCCCCCCCCCCCC	48.62	23911959
800	Phosphorylation	KGSKSEDSELPPQTA CCCCCCCCCCCCCCC	36.66	29507054
800 (in isoform 3)	Phosphorylation	-	36.66	24719451
818	Phosphorylation	PSEGSRRSSSDLITL CCCCCCCCCCCCEEE	32.84	30266825
819	Phosphorylation	SEGSRRSSSDLITLP CCCCCCCCCCCEEEC	26.51	30266825
820	Phosphorylation	EGSRRSSSDLITLPA CCCCCCCCCCEEECC	37.37	30266825
824	Phosphorylation	RSSSDLITLPATTPP CCCCCCEEECCCCCC	33.70	30266825
828	Phosphorylation	DLITLPATTPPCPTK CCEEECCCCCCCCCC	37.58	20363803
829	Phosphorylation	LITLPATTPPCPTKK CEEECCCCCCCCCCC	27.60	20363803
834	Phosphorylation	ATTPPCPTKKEWEGP CCCCCCCCCCCCCCC	62.56	23090842
857	Phosphorylation	AYQKVQDSEISFPAG HHHHHCCCCCCCCCC	21.53	24667141
897	Phosphorylation	PSHYLVLDENEQPDP CCEEEEECCCCCCCC	49.55	18669648
897 (in isoform 3)	Phosphorylation	-	49.55	24719451
915	Acetylation	ELDTVPAKGRQNEGK CCCCCCCCCCCCCCC	48.86	20167786
918 (in isoform 3)	Phosphorylation	-	62.08	24719451
922	Acetylation	KGRQNEGKSDSLEKI CCCCCCCCCCHHHHH	44.93	30592981
923	Phosphorylation	GRQNEGKSDSLEKIE CCCCCCCCCHHHHHH	43.20	28857561
925	Phosphorylation	QNEGKSDSLEKIERR CCCCCCCHHHHHHHH	45.58	30576142
928	Ubiquitination	GKSDSLEKIERRVQA CCCCHHHHHHHHHHH	55.98	-
946	Phosphorylation	VNQSKKATPPIPSKP HCCCCCCCCCCCCCC	38.18	30576142
951	Phosphorylation	KATPPIPSKPPGGFG CCCCCCCCCCCCCCC	59.52	24719451
953 (in isoform 3)	Phosphorylation	-	36.79	27251275
957	Phosphorylation	PSKPPGGFGKTSGTP CCCCCCCCCCCCCCC	12.90	20068231
959	Methylation	KPPGGFGKTSGTPAV CCCCCCCCCCCCCCC	36.94	115979915
963	Phosphorylation	GFGKTSGTPAVKMRN CCCCCCCCCCCEECC	14.08	29396449
974	Phosphorylation	KMRNGVRQVAVRPQS EECCCEEEEEECCCE	25.72	20068231
974 (in isoform 3)	Phosphorylation	-	25.72	24719451
981	Phosphorylation	QVAVRPQSVFVSPPP EEEECCCEEEECCCC	21.87	23312004
985	Phosphorylation	RPQSVFVSPPPKDNN CCCEEEECCCCCCCC	21.89	20068231
988	Phosphorylation	SVFVSPPPKDNNLSC EEEECCCCCCCCCCH	61.08	18669648
988 (in isoform 3)	Phosphorylation	-	61.08	27251275
989	Phosphorylation	VFVSPPPKDNNLSCA EEECCCCCCCCCCHH	78.01	18669648
989 (in isoform 3)	Phosphorylation	-	78.01	24719451
1002	Phosphorylation	CALRRNESLTATDGL HHHHCCCCCCCCCCC	34.27	29255136
1004	Phosphorylation	LRRNESLTATDGLRG HHCCCCCCCCCCCCC	36.47	22167270
1006	Phosphorylation	RNESLTATDGLRGVR CCCCCCCCCCCCCHH	25.93	23403867
1010	Methylation	LTATDGLRGVRRNSS CCCCCCCCCHHCCCC	47.27	58860123
1010	Phosphorylation	LTATDGLRGVRRNSS CCCCCCCCCHHCCCC	47.27	17525332
1010 (in isoform 3)	Phosphorylation	-	47.27	24719451
1015 (in isoform 3)	Phosphorylation	-	31.29	24719451
1016	Phosphorylation	LRGVRRNSSFSTARS CCCHHCCCCHHHHHH	30.83	29255136
1017	Phosphorylation	RGVRRNSSFSTARSA CCHHCCCCHHHHHHH	27.11	29255136
1019	Phosphorylation	VRRNSSFSTARSAAA HHCCCCHHHHHHHHH	24.09	25850435
1020	Phosphorylation	RRNSSFSTARSAAAE HCCCCHHHHHHHHHH	24.87	30576142
1024 (in isoform 3)	Phosphorylation	-	12.72	27251275
1028	Phosphorylation	ARSAAAEAKGRLAER HHHHHHHHHHHHHHH	18.18	20068231
1028 (in isoform 3)	Phosphorylation	-	18.18	24719451
1038	Phosphorylation	RLAERAASQGSDSPL HHHHHHHHCCCCCCC	33.80	17525332
1041	Phosphorylation	ERAASQGSDSPLLPA HHHHHCCCCCCCCCC	27.55	30266825
1043	Phosphorylation	AASQGSDSPLLPAQR HHHCCCCCCCCCCCC	21.10	30266825
1052	Phosphorylation	LLPAQRNSIPVSPVR CCCCCCCCCCCCCCC	30.38	23403867
1056	Phosphorylation	QRNSIPVSPVRPKPI CCCCCCCCCCCCCCC	16.60	29255136
1126	Phosphorylation	PFKGWVPSNYLEKKN CCCCCCCHHHHHCCC	28.61	30619164
1128	Phosphorylation	KGWVPSNYLEKKN-- CCCCCHHHHHCCC--	22.15	30619164

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SPD2A_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SPD2A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SPD2A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KCTD3_HUMAN	KCTD3	physical	27173435
KI13B_HUMAN	KIF13B	physical	27173435
ZBT21_HUMAN	ZBTB21	physical	27173435
GGYF1_HUMAN	GIGYF1	physical	27173435
LRFN1_HUMAN	LRFN1	physical	27173435
DEN1A_HUMAN	DENND1A	physical	27173435
SRGP2_HUMAN	SRGAP2	physical	27173435
SI1L1_HUMAN	SIPA1L1	physical	27173435
RTKN_HUMAN	RTKN	physical	27173435
MAST3_HUMAN	MAST3	physical	27173435
LIMA1_HUMAN	LIMA1	physical	27173435
CING_HUMAN	CGN	physical	27173435
MAGI1_HUMAN	MAGI1	physical	27173435
DEN4C_HUMAN	DENND4C	physical	27173435
TESK2_HUMAN	TESK2	physical	27173435
DCLK1_HUMAN	DCLK1	physical	27173435
PPM1H_HUMAN	PPM1H	physical	27173435
ZN638_HUMAN	ZNF638	physical	27173435
SRS12_HUMAN	SRSF12	physical	27173435
SYDE1_HUMAN	SYDE1	physical	27173435
SIN1_HUMAN	MAPKAP1	physical	27173435
AGAP1_HUMAN	AGAP1	physical	27173435
MPIP2_HUMAN	CDC25B	physical	27173435
CDK16_HUMAN	CDK16	physical	27173435
HDAC4_HUMAN	HDAC4	physical	27173435
F110B_HUMAN	FAM110B	physical	27173435
UBP21_HUMAN	USP21	physical	27173435
AN34A_HUMAN	ANKRD34A	physical	27173435
FA53C_HUMAN	FAM53C	physical	27173435
NF1_HUMAN	NF1	physical	27173435
CBY1_HUMAN	CBY1	physical	27173435
LPIN3_HUMAN	LPIN3	physical	27173435
NADK_HUMAN	NADK	physical	27173435
F110A_HUMAN	FAM110A	physical	27173435
TIAM1_HUMAN	TIAM1	physical	27173435
MPIP3_HUMAN	CDC25C	physical	27173435
M3K21_HUMAN	KIAA1804	physical	27173435
NGAP_HUMAN	RASAL2	physical	27173435
CAMP2_HUMAN	CAMSAP2	physical	27173435
GGYF2_HUMAN	GIGYF2	physical	27173435
PKHA7_HUMAN	PLEKHA7	physical	27173435
MELK_HUMAN	MELK	physical	27173435
GAB2_HUMAN	GAB2	physical	27173435
KIF1C_HUMAN	KIF1C	physical	27173435
TBC25_HUMAN	TBC1D25	physical	27173435
NAV1_HUMAN	NAV1	physical	27173435
RPTOR_HUMAN	RPTOR	physical	27173435
TANC2_HUMAN	TANC2	physical	27173435
PTN13_HUMAN	PTPN13	physical	27173435
RGPS2_HUMAN	RALGPS2	physical	27173435
DEP1B_HUMAN	DEPDC1B	physical	27173435
PTN14_HUMAN	PTPN14	physical	27173435
STA13_HUMAN	STARD13	physical	27173435
OSBL6_HUMAN	OSBPL6	physical	27173435
AFAD_HUMAN	MLLT4	physical	27173435
HDAC7_HUMAN	HDAC7	physical	27173435
PKHA5_HUMAN	PLEKHA5	physical	27173435
LARP1_HUMAN	LARP1	physical	27173435
SH3B4_HUMAN	SH3BP4	physical	27173435
CHK1_HUMAN	CHEK1	physical	27173435
KIF1B_HUMAN	KIF1B	physical	27173435
INP5E_HUMAN	INPP5E	physical	27173435
RAB3I_HUMAN	RAB3IP	physical	27173435

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SPD2A_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1002, AND MASSSPECTROMETRY.	19690332 [Abstract]
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