F110A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F110A_HUMAN
• UniProt AC: Q9BQ89
• Protein Name: Protein FAM110A
• Gene Name: FAM110A
• Organism: Homo sapiens (Human).
• Sequence Length: 295
• Subcellular Localization: Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Distributed throughout the cytoplasm during mitosis, accumulating at spindle poles.
• Protein Sequence: MPVHTLSPGAPSAPALPCRLRTRVPGYLLRGPADGGARKPSAVERLEADKAKYVKSLHVANTRQEPVQPLLSKQPLFSPETRRTVLTPSRRALPGPCRRPQLDLDILSSLIDLCDSPVSPAEASRTPGRAEGAGRPPPATPPRPPPSTSAVRRVDVRPLPASPARPCPSPGPAAASSPARPPGLQRSKSDLSERFSRAAADLERFFNFCGLDPEEARGLGVAHLARASSDIVSLAGPSAGPGSSEGGCSRRSSVTVEERARERVPYGVSVVERNARVIKWLYGLRQARESPAAEG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MPVHTLSPGAPS ---CCCCCCCCCCCC	29.21	22199227
7	Phosphorylation	-MPVHTLSPGAPSAP -CCCCCCCCCCCCCC	23.57	25849741
12	Phosphorylation	TLSPGAPSAPALPCR CCCCCCCCCCCCCCE	46.48	23186163
27	Phosphorylation	LRTRVPGYLLRGPAD EECCCCCEEEECCCC	9.11	-
41	Phosphorylation	DGGARKPSAVERLEA CCCCCCCHHHHHHHH	48.24	-
55	Ubiquitination	ADKAKYVKSLHVANT HHHHHHHHHHHCCCC	44.18	29967540
78	Phosphorylation	LSKQPLFSPETRRTV HHCCCCCCHHHCCEE	29.52	30266825
81	Phosphorylation	QPLFSPETRRTVLTP CCCCCHHHCCEEECC	28.92	30266825
84	Phosphorylation	FSPETRRTVLTPSRR CCHHHCCEEECCCCC	19.31	-
87	Phosphorylation	ETRRTVLTPSRRALP HHCCEEECCCCCCCC	18.19	23898821
108	Phosphorylation	QLDLDILSSLIDLCD CCCHHHHHHHHHHHC	24.35	28102081
109	Phosphorylation	LDLDILSSLIDLCDS CCHHHHHHHHHHHCC	26.37	28102081
116	Phosphorylation	SLIDLCDSPVSPAEA HHHHHHCCCCCHHHH	26.63	28102081
119	Phosphorylation	DLCDSPVSPAEASRT HHHCCCCCHHHHCCC	23.06	22617229
124	Phosphorylation	PVSPAEASRTPGRAE CCCHHHHCCCCCCCC	28.35	28102081
140	Phosphorylation	AGRPPPATPPRPPPS CCCCCCCCCCCCCCC	39.33	26657352
147	Phosphorylation	TPPRPPPSTSAVRRV CCCCCCCCCCCCCEE	40.54	23312004
148	Phosphorylation	PPRPPPSTSAVRRVD CCCCCCCCCCCCEEE	26.86	27251275
149	Phosphorylation	PRPPPSTSAVRRVDV CCCCCCCCCCCEEEC	29.16	23312004
162	Phosphorylation	DVRPLPASPARPCPS ECCCCCCCCCCCCCC	19.70	23312004
169	Phosphorylation	SPARPCPSPGPAAAS CCCCCCCCCCCCCCC	49.56	23312004
176	Phosphorylation	SPGPAAASSPARPPG CCCCCCCCCCCCCCC	31.93	23312004
177	Phosphorylation	PGPAAASSPARPPGL CCCCCCCCCCCCCCC	20.18	28348404
187	Phosphorylation	RPPGLQRSKSDLSER CCCCCCCCHHHHHHH	24.45	26699800
189	Phosphorylation	PGLQRSKSDLSERFS CCCCCCHHHHHHHHH	45.06	22617229
192	Phosphorylation	QRSKSDLSERFSRAA CCCHHHHHHHHHHHH	31.55	22617229
228	Phosphorylation	VAHLARASSDIVSLA HHHHHHHHCCCCHHC	24.00	28450419
229	Phosphorylation	AHLARASSDIVSLAG HHHHHHHCCCCHHCC	30.30	25849741
233	Phosphorylation	RASSDIVSLAGPSAG HHHCCCCHHCCCCCC	16.91	28450419
238	Phosphorylation	IVSLAGPSAGPGSSE CCHHCCCCCCCCCCC	44.96	28450419
243	Phosphorylation	GPSAGPGSSEGGCSR CCCCCCCCCCCCCCC	28.49	22115753
244	Phosphorylation	PSAGPGSSEGGCSRR CCCCCCCCCCCCCCC	46.29	22115753
249	Phosphorylation	GSSEGGCSRRSSVTV CCCCCCCCCCCCCCH	33.72	28450419
252	Phosphorylation	EGGCSRRSSVTVEER CCCCCCCCCCCHHHH	28.22	25849741
253	Phosphorylation	GGCSRRSSVTVEERA CCCCCCCCCCHHHHH	21.72	25849741
255	Phosphorylation	CSRRSSVTVEERARE CCCCCCCCHHHHHHH	24.93	28985074
266	Phosphorylation	RARERVPYGVSVVER HHHHHCCCCCCHHHH	27.57	28985074

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F110A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F110A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F110A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
USBP1_HUMAN	USHBP1	physical	25416956
TRI69_HUMAN	TRIM69	physical	25416956
F110B_HUMAN	FAM110B	physical	27173435
SYDE1_HUMAN	SYDE1	physical	27173435
MAGI1_HUMAN	MAGI1	physical	27173435

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.