dbPTM

CAMP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CAMP2_HUMAN
UniProt AC	Q08AD1
Protein Name	Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305}
Gene Name	CAMSAP2 {ECO:0000312\|HGNC:HGNC:29188}
Organism	Homo sapiens (Human).
Sequence Length	1489
Subcellular Localization	Cytoplasm, cytoskeleton . Golgi apparatus . Associated with the minus-end of microtubules and also detected at the centrosomes (PubMed:23169647, PubMed:24486153, PubMed:24908486, PubMed:24706919, PubMed:27666745, PubMed:28814570). Decorates the minus
Protein Description	Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. [PubMed: 23169647]
Protein Sequence	MGDAADPREMRKTFIVPAIKPFDHYDFSRAKIACNLAWLVAKAFGTENVPEELQEPFYTDQYDQEHIKPPVVNLLLSAELYCRAGSLILKSDAAKPLLGHDAVIQALAQKGLYVTDQEKLVTERDLHKKPIQMSAHLAMIDTLMMAYTVEMVSIEKVIACAQQYSAFFQATDLPYDIEDAVMYWINKVNEHLKDIMEQEQKLKEHHTVEAPGGQKSPSKWFWKLVPARYRKEQTLLKQLPCIPLVENLLKDGTDGCALAALIHFYCPDVVRLEDICLKETMSLADSLYNLQLIQEFCQEYLNQCCHFTLEDMLYAASSIKSNYLVFMAELFWWFEVVKPSFVQPRVVRPQGAEPVKDMPSIPVLNAAKRNVLDSSSDFPSSGEGATFTQSHHHLPSRYSRPQAHSSASGGIRRSSSMSYVDGFIGTWPKEKRSSVHGVSFDISFDKEDSVQRSTPNRGITRSISNEGLTLNNSHVSKHIRKNLSFKPINGEEEAESIEEELNIDSHSDLKSCVPLNTNELNSNENIHYKLPNGALQNRILLDEFGNQIETPSIEEALQIIHDTEKSPHTPQPDQIANGFFLHSQEMSILNSNIKLNQSSPDNVTDTKGALSPITDNTEVDTGIHVPSEDIPETMDEDSSLRDYTVSLDSDMDDASKFLQDYDIRTGNTREALSPCPSTVSTKSQPGSSASSSSGVKMTSFAEQKFRKLNHTDGKSSGSSSQKTTPEGSELNIPHVVAWAQIPEETGLPQGRDTTQLLASEMVHLRMKLEEKRRAIEAQKKKMEAAFTKQRQKMGRTAFLTVVKKKGDGISPLREEAAGAEDEKVYTDRAKEKESQKTDGQRSKSLADIKESMENPQAKWLKSPTTPIDPEKQWNLASPSEETLNEGEILEYTKSIEKLNSSLHFLQQEMQRLSLQQEMLMQMREQQSWVISPPQPSPQKQIRDFKPSKQAGLSSAIAPFSSDSPRPTHPSPQSSNRKSASFSVKSQRTPRPNELKITPLNRTLTPPRSVDSLPRLRRFSPSQVPIQTRSFVCFGDDGEPQLKESKPKEEVKKEELESKGTLEQRGHNPEEKEIKPFESTVSEVLSLPVTETVCLTPNEDQLNQPTEPPPKPVFPPTAPKNVNLIEVSLSDLKPPEKADVPVEKYDGESDKEQFDDDQKVCCGFFFKDDQKAENDMAMKRAALLEKRLRREKETQLRKQQLEAEMEHKKEETRRKTEEERQKKEDERARREFIRQEYMRRKQLKLMEDMDTVIKPRPQVVKQKKQRPKSIHRDHIESPKTPIKGPPVSSLSLASLNTGDNESVHSGKRTPRSESVEGFLSPSRCGSRNGEKDWENASTTSSVASGTEYTGPKLYKEPSAKSNKHIIQNALAHCCLAGKVNEGQKKKILEEMEKSDANNFLILFRDSGCQFRSLYTYCPETEEINKLTGIGPKSITKKMIEGLYKYNSDRKQFSHIPAKTLSASVDAITIHSHLWQTKRPVTPKKLLPTKA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Acetylation	ADPREMRKTFIVPAI CCHHHHHHHEEEEEC	46.61	7410041
86	Phosphorylation	ELYCRAGSLILKSDA HHHHHHCCEEECCCC	15.97	-
95	Ubiquitination	ILKSDAAKPLLGHDA EECCCCCCHHCCCHH	37.61	-
134	Phosphorylation	HKKPIQMSAHLAMID HCCCCCHHHHHHHHH	9.00	28634298
142	Phosphorylation	AHLAMIDTLMMAYTV HHHHHHHHHHHHHHH	12.96	28634298
147	Phosphorylation	IDTLMMAYTVEMVSI HHHHHHHHHHEECCH	8.07	28634298
148	Phosphorylation	DTLMMAYTVEMVSIE HHHHHHHHHEECCHH	10.64	28634298
153	Phosphorylation	AYTVEMVSIEKVIAC HHHHEECCHHHHHHH	24.58	28634298
216	Phosphorylation	EAPGGQKSPSKWFWK CCCCCCCCCCCCHHH	26.90	27732954
218	Phosphorylation	PGGQKSPSKWFWKLV CCCCCCCCCCHHHHH	50.00	27732954
360	Phosphorylation	EPVKDMPSIPVLNAA CCCCCCCCCCCCCHH	32.65	20068231
364 (in isoform 2)	Phosphorylation	-	2.79	21815630
365 (in isoform 2)	Phosphorylation	-	37.78	21712546
368	Methylation	IPVLNAAKRNVLDSS CCCCCHHHCCCCCCC	41.94	-
376	Phosphorylation	RNVLDSSSDFPSSGE CCCCCCCCCCCCCCC	47.42	29214152
379 (in isoform 2)	Phosphorylation	-	32.35	25159151
381 (in isoform 2)	Phosphorylation	-	40.89	25159151
398	Phosphorylation	HHHLPSRYSRPQAHS CCCCCCCCCCCCCCC	17.23	-
405	Phosphorylation	YSRPQAHSSASGGIR CCCCCCCCCCCCCCC	30.52	22210691
406	Phosphorylation	SRPQAHSSASGGIRR CCCCCCCCCCCCCCC	19.31	22210691
408	Phosphorylation	PQAHSSASGGIRRSS CCCCCCCCCCCCCCC	39.23	28555341
414	Phosphorylation	ASGGIRRSSSMSYVD CCCCCCCCCCCCEEC	19.54	23927012
415	Phosphorylation	SGGIRRSSSMSYVDG CCCCCCCCCCCEECC	28.40	23927012
416	Phosphorylation	GGIRRSSSMSYVDGF CCCCCCCCCCEECCC	17.00	23927012
418	Phosphorylation	IRRSSSMSYVDGFIG CCCCCCCCEECCCCC	24.77	23927012
419	Phosphorylation	RRSSSMSYVDGFIGT CCCCCCCEECCCCCC	8.23	23927012
426	Phosphorylation	YVDGFIGTWPKEKRS EECCCCCCCCHHHCC	33.50	23927012
433	Phosphorylation	TWPKEKRSSVHGVSF CCCHHHCCCCCEEEE	48.02	23927012
434	Phosphorylation	WPKEKRSSVHGVSFD CCHHHCCCCCEEEEE	23.36	30576142
439	Phosphorylation	RSSVHGVSFDISFDK CCCCCEEEEEEEECC	23.07	23927012
443	Phosphorylation	HGVSFDISFDKEDSV CEEEEEEEECCHHCC	29.27	25159151
453	Phosphorylation	KEDSVQRSTPNRGIT CHHCCCCCCCCCCCC	31.00	19691289
454	Phosphorylation	EDSVQRSTPNRGITR HHCCCCCCCCCCCCC	27.11	25159151
462	Phosphorylation	PNRGITRSISNEGLT CCCCCCCEECCCCCE	23.01	22167270
464	Phosphorylation	RGITRSISNEGLTLN CCCCCEECCCCCEEC	30.03	29255136
469	Phosphorylation	SISNEGLTLNNSHVS EECCCCCEECCHHHH	37.99	30266825
473	Phosphorylation	EGLTLNNSHVSKHIR CCCEECCHHHHHHHH	24.96	23927012
476	Phosphorylation	TLNNSHVSKHIRKNL EECCHHHHHHHHHCC	17.06	23927012
484	Phosphorylation	KHIRKNLSFKPINGE HHHHHCCCCCCCCCH	40.39	24719451
496	Phosphorylation	NGEEEAESIEEELNI CCHHHHHHHHHHHCC	42.20	25159151
505	Phosphorylation	EEELNIDSHSDLKSC HHHHCCCCCCCHHHC	22.54	23090842
507	Phosphorylation	ELNIDSHSDLKSCVP HHCCCCCCCHHHCCC	48.90	23090842
511	Phosphorylation	DSHSDLKSCVPLNTN CCCCCHHHCCCCCCC	27.87	28555341
517	Phosphorylation	KSCVPLNTNELNSNE HHCCCCCCCCCCCCC	37.44	27732954
522	Phosphorylation	LNTNELNSNENIHYK CCCCCCCCCCCCCCC	59.13	25849741
528	Phosphorylation	NSNENIHYKLPNGAL CCCCCCCCCCCCHHH	15.49	25159151
529	Ubiquitination	SNENIHYKLPNGALQ CCCCCCCCCCCHHHH	43.22	-
566	Phosphorylation	IIHDTEKSPHTPQPD HHHCCCCCCCCCCCH	18.71	25849741
569	Phosphorylation	DTEKSPHTPQPDQIA CCCCCCCCCCCHHHC	27.31	22617229
587	Phosphorylation	FLHSQEMSILNSNIK ECHHHHHHHHHCCCC	24.15	20068231
598	Phosphorylation	SNIKLNQSSPDNVTD CCCCCCCCCCCCCCC	42.64	29255136
599	Phosphorylation	NIKLNQSSPDNVTDT CCCCCCCCCCCCCCC	26.89	19664994
604	Phosphorylation	QSSPDNVTDTKGALS CCCCCCCCCCCCCCC	44.18	23403867
606	Phosphorylation	SPDNVTDTKGALSPI CCCCCCCCCCCCCCC	23.24	22167270
611	Phosphorylation	TDTKGALSPITDNTE CCCCCCCCCCCCCCC	17.45	30266825
614	Phosphorylation	KGALSPITDNTEVDT CCCCCCCCCCCCCCC	26.95	23663014
617	Phosphorylation	LSPITDNTEVDTGIH CCCCCCCCCCCCCCC	39.95	30266825
621	Phosphorylation	TDNTEVDTGIHVPSE CCCCCCCCCCCCCHH	43.12	30266825
627	Phosphorylation	DTGIHVPSEDIPETM CCCCCCCHHHCCCCC	46.97	30266825
633	Phosphorylation	PSEDIPETMDEDSSL CHHHCCCCCCCCCCC	25.27	27251275
638	Phosphorylation	PETMDEDSSLRDYTV CCCCCCCCCCCCEEE	29.26	27732954
639	Phosphorylation	ETMDEDSSLRDYTVS CCCCCCCCCCCEEEE	39.48	27732954
643	Phosphorylation	EDSSLRDYTVSLDSD CCCCCCCEEEECCCC	11.56	27251275
644	Phosphorylation	DSSLRDYTVSLDSDM CCCCCCEEEECCCCC	14.12	29978859
646	Phosphorylation	SLRDYTVSLDSDMDD CCCCEEEECCCCCCH	20.75	29978859
649	Phosphorylation	DYTVSLDSDMDDASK CEEEECCCCCCHHHH	39.88	29978859
655	Phosphorylation	DSDMDDASKFLQDYD CCCCCHHHHHHHHCC	30.82	29978859
661	Phosphorylation	ASKFLQDYDIRTGNT HHHHHHHCCCCCCCC	10.58	27642862
665	Phosphorylation	LQDYDIRTGNTREAL HHHCCCCCCCCCHHC	34.81	28555341
673	Phosphorylation	GNTREALSPCPSTVS CCCCHHCCCCCCCCC	31.35	29255136
677	Phosphorylation	EALSPCPSTVSTKSQ HHCCCCCCCCCCCCC	48.43	23403867
678	Phosphorylation	ALSPCPSTVSTKSQP HCCCCCCCCCCCCCC	12.01	23403867
680	Phosphorylation	SPCPSTVSTKSQPGS CCCCCCCCCCCCCCC	30.15	23403867
681	O-linked_Glycosylation	PCPSTVSTKSQPGSS CCCCCCCCCCCCCCC	30.31	28657654
681	Phosphorylation	PCPSTVSTKSQPGSS CCCCCCCCCCCCCCC	30.31	23403867
683	Phosphorylation	PSTVSTKSQPGSSAS CCCCCCCCCCCCCCC	41.52	27251275
687	Phosphorylation	STKSQPGSSASSSSG CCCCCCCCCCCCCCC	29.43	22468782
690	Phosphorylation	SQPGSSASSSSGVKM CCCCCCCCCCCCCCC	32.47	25627689
691	Phosphorylation	QPGSSASSSSGVKMT CCCCCCCCCCCCCCC	28.39	25627689
692	Phosphorylation	PGSSASSSSGVKMTS CCCCCCCCCCCCCCH	28.72	25627689
693	Phosphorylation	GSSASSSSGVKMTSF CCCCCCCCCCCCCHH	49.94	25159151
698	Phosphorylation	SSSGVKMTSFAEQKF CCCCCCCCHHHHHHH	18.25	27732954
699	Phosphorylation	SSGVKMTSFAEQKFR CCCCCCCHHHHHHHH	20.97	27732954
711	Phosphorylation	KFRKLNHTDGKSSGS HHHHCCCCCCCCCCC	45.43	18452278
720	Phosphorylation	GKSSGSSSQKTTPEG CCCCCCCCCCCCCCC	37.08	-
723	Phosphorylation	SGSSSQKTTPEGSEL CCCCCCCCCCCCCCC	39.69	25159151
724	Phosphorylation	GSSSQKTTPEGSELN CCCCCCCCCCCCCCC	26.78	25159151
728	Phosphorylation	QKTTPEGSELNIPHV CCCCCCCCCCCCCEE	36.93	27732954
759	Phosphorylation	DTTQLLASEMVHLRM CHHHHHHHHHHHHHH	26.62	28555341
810	Phosphorylation	KKKGDGISPLREEAA EECCCCCCHHHHHHC	24.34	29255136
825	Phosphorylation	GAEDEKVYTDRAKEK CCCCCCCCHHHHHHH	17.62	29978859
826	Phosphorylation	AEDEKVYTDRAKEKE CCCCCCCHHHHHHHH	23.23	29978859
834	Phosphorylation	DRAKEKESQKTDGQR HHHHHHHHHCCCCCC	48.31	30576142
837	Phosphorylation	KEKESQKTDGQRSKS HHHHHHCCCCCCCHH	37.41	30576142
842	Phosphorylation	QKTDGQRSKSLADIK HCCCCCCCHHHHHHH	20.78	23927012
844	Phosphorylation	TDGQRSKSLADIKES CCCCCCHHHHHHHHH	30.00	23927012
851	Phosphorylation	SLADIKESMENPQAK HHHHHHHHHHCCCCC	26.79	19691289
861	Methylation	NPQAKWLKSPTTPID CCCCCCCCCCCCCCC	53.96	-
862	Phosphorylation	PQAKWLKSPTTPIDP CCCCCCCCCCCCCCH	25.88	30266825
864	Phosphorylation	AKWLKSPTTPIDPEK CCCCCCCCCCCCHHH	52.90	30266825
865	Phosphorylation	KWLKSPTTPIDPEKQ CCCCCCCCCCCHHHC	22.94	30266825
877	Phosphorylation	EKQWNLASPSEETLN HHCCCCCCCCHHCCC	31.93	22199227
879	Phosphorylation	QWNLASPSEETLNEG CCCCCCCCHHCCCHH	45.64	22199227
882	Phosphorylation	LASPSEETLNEGEIL CCCCCHHCCCHHHHH	30.72	27732954
900	Phosphorylation	KSIEKLNSSLHFLQQ HHHHHHHHHHHHHHH	44.72	25159151
901	Phosphorylation	SIEKLNSSLHFLQQE HHHHHHHHHHHHHHH	25.45	25159151
913	Phosphorylation	QQEMQRLSLQQEMLM HHHHHHHHHHHHHHH	26.73	28555341
927	Phosphorylation	MQMREQQSWVISPPQ HHHHHHCCCEECCCC	24.01	23186163
931	Phosphorylation	EQQSWVISPPQPSPQ HHCCCEECCCCCCCC	22.40	22167270
936	Phosphorylation	VISPPQPSPQKQIRD EECCCCCCCCHHHCC	34.41	22167270
953	Phosphorylation	PSKQAGLSSAIAPFS HHHHCCCCCCCCCCC	19.46	20873877
954	Phosphorylation	SKQAGLSSAIAPFSS HHHCCCCCCCCCCCC	28.83	20873877
960	Phosphorylation	SSAIAPFSSDSPRPT CCCCCCCCCCCCCCC	31.98	25849741
961	Phosphorylation	SAIAPFSSDSPRPTH CCCCCCCCCCCCCCC	42.35	22167270
963	Phosphorylation	IAPFSSDSPRPTHPS CCCCCCCCCCCCCCC	25.42	22167270
967	Phosphorylation	SSDSPRPTHPSPQSS CCCCCCCCCCCCCCC	47.93	22167270
970	Phosphorylation	SPRPTHPSPQSSNRK CCCCCCCCCCCCCCC	28.15	22167270
973	Phosphorylation	PTHPSPQSSNRKSAS CCCCCCCCCCCCCCC	32.72	22167270
974	Phosphorylation	THPSPQSSNRKSASF CCCCCCCCCCCCCCE	35.09	22167270
977	Acetylation	SPQSSNRKSASFSVK CCCCCCCCCCCEEEC	55.41	7306255
977	Methylation	SPQSSNRKSASFSVK CCCCCCCCCCCEEEC	55.41	-
978	Phosphorylation	PQSSNRKSASFSVKS CCCCCCCCCCEEECC	26.38	29496963
980	Phosphorylation	SSNRKSASFSVKSQR CCCCCCCCEEECCCC	25.75	29743597
982	Phosphorylation	NRKSASFSVKSQRTP CCCCCCEEECCCCCC	26.58	23312004
984	Methylation	KSASFSVKSQRTPRP CCCCEEECCCCCCCC	39.41	-
985	Phosphorylation	SASFSVKSQRTPRPN CCCEEECCCCCCCCC	23.80	25159151
988	Phosphorylation	FSVKSQRTPRPNELK EEECCCCCCCCCCCE	18.93	18669648
997	Phosphorylation	RPNELKITPLNRTLT CCCCCEEECCCCCCC	21.82	21815630
1002	Phosphorylation	KITPLNRTLTPPRSV EEECCCCCCCCCCCC	33.63	25159151
1004	Phosphorylation	TPLNRTLTPPRSVDS ECCCCCCCCCCCCCC	30.54	25159151
1008	Phosphorylation	RTLTPPRSVDSLPRL CCCCCCCCCCCCCCH	35.73	25159151
1011	Phosphorylation	TPPRSVDSLPRLRRF CCCCCCCCCCCHHCC	37.81	21815630
1014	Methylation	RSVDSLPRLRRFSPS CCCCCCCCHHCCCCC	46.23	-
1019	Phosphorylation	LPRLRRFSPSQVPIQ CCCHHCCCCCCCCCC	23.10	29255136
1021	Phosphorylation	RLRRFSPSQVPIQTR CHHCCCCCCCCCCCC	42.48	30266825
1027	Phosphorylation	PSQVPIQTRSFVCFG CCCCCCCCCEEEEEC	29.06	20068231
1029	Phosphorylation	QVPIQTRSFVCFGDD CCCCCCCEEEEECCC	25.97	18669648
1057	Phosphorylation	VKKEELESKGTLEQR HCHHHHHHHCCHHHC	49.35	29514088
1060	Phosphorylation	EELESKGTLEQRGHN HHHHHHCCHHHCCCC	30.75	29514088
1089	Phosphorylation	EVLSLPVTETVCLTP HHHCCCCCEEEEECC	24.81	25627689
1091	Phosphorylation	LSLPVTETVCLTPNE HCCCCCEEEEECCCH	13.73	25627689
1095	Phosphorylation	VTETVCLTPNEDQLN CCEEEEECCCHHHCC	20.95	25627689
1127	Phosphorylation	NVNLIEVSLSDLKPP CCEEEEEEHHHCCCC	14.90	24719451
1144	Phosphorylation	ADVPVEKYDGESDKE CCCCCCCCCCCCCHH	18.70	30278072
1148	Phosphorylation	VEKYDGESDKEQFDD CCCCCCCCCHHHCCC	60.56	29255136
1170	Acetylation	FFFKDDQKAENDMAM EEECCCHHHHHHHHH	65.74	12654879
1178	Acetylation	AENDMAMKRAALLEK HHHHHHHHHHHHHHH	29.37	12654891
1250	Phosphorylation	KLMEDMDTVIKPRPQ HHHHCCHHHCCCCHH	19.93	19664994
1268	Phosphorylation	QKKQRPKSIHRDHIE CCCCCCCCCCHHHCC	26.72	23927012
1276	Phosphorylation	IHRDHIESPKTPIKG CCHHHCCCCCCCCCC	30.97	23927012
1279	Phosphorylation	DHIESPKTPIKGPPV HHCCCCCCCCCCCCC	33.36	25159151
1282	Acetylation	ESPKTPIKGPPVSSL CCCCCCCCCCCCCEE	67.57	26051181
1287	Phosphorylation	PIKGPPVSSLSLASL CCCCCCCCEEEEEEC	31.19	29255136
1288	Phosphorylation	IKGPPVSSLSLASLN CCCCCCCEEEEEECC	23.39	29255136
1290	Phosphorylation	GPPVSSLSLASLNTG CCCCCEEEEEECCCC	24.68	29255136
1293	Phosphorylation	VSSLSLASLNTGDNE CCEEEEEECCCCCCC	27.69	29255136
1296	Phosphorylation	LSLASLNTGDNESVH EEEEECCCCCCCCCC	51.73	29255136
1301	Phosphorylation	LNTGDNESVHSGKRT CCCCCCCCCCCCCCC	31.24	25850435
1304	Phosphorylation	GDNESVHSGKRTPRS CCCCCCCCCCCCCCC	43.80	25850435
1308	Phosphorylation	SVHSGKRTPRSESVE CCCCCCCCCCCCCCC	26.92	25159151
1311	Phosphorylation	SGKRTPRSESVEGFL CCCCCCCCCCCCCCC	35.11	29255136
1313	Phosphorylation	KRTPRSESVEGFLSP CCCCCCCCCCCCCCC	27.07	29255136
1319	Phosphorylation	ESVEGFLSPSRCGSR CCCCCCCCCCCCCCC	20.68	19664994
1321	Phosphorylation	VEGFLSPSRCGSRNG CCCCCCCCCCCCCCC	36.51	30266825
1336	Phosphorylation	EKDWENASTTSSVAS CCCHHHCCCCCCCCC	43.74	25159151
1337	Phosphorylation	KDWENASTTSSVASG CCHHHCCCCCCCCCC	28.43	25159151
1338	Phosphorylation	DWENASTTSSVASGT CHHHCCCCCCCCCCC	19.26	25159151
1339	Phosphorylation	WENASTTSSVASGTE HHHCCCCCCCCCCCC	23.93	25159151
1340	Phosphorylation	ENASTTSSVASGTEY HHCCCCCCCCCCCCC	21.43	25159151
1343	Phosphorylation	STTSSVASGTEYTGP CCCCCCCCCCCCCCC	44.06	25159151
1345	Phosphorylation	TSSVASGTEYTGPKL CCCCCCCCCCCCCCC	24.27	23090842
1347	Phosphorylation	SVASGTEYTGPKLYK CCCCCCCCCCCCCCC	19.48	27732954
1348	Phosphorylation	VASGTEYTGPKLYKE CCCCCCCCCCCCCCC	40.55	27732954
1354	Ubiquitination	YTGPKLYKEPSAKSN CCCCCCCCCCCCCCC	73.85	-
1413	Phosphorylation	GCQFRSLYTYCPETE CCCEEEEEECCCCCH	9.26	-
1415	Phosphorylation	QFRSLYTYCPETEEI CEEEEEECCCCCHHH	7.76	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
464	S	Phosphorylation	Kinase	CHEK1	O14757	GPS

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CAMP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CAMP2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KCTD3_HUMAN	KCTD3	physical	27173435
KI13B_HUMAN	KIF13B	physical	27173435
ZBT21_HUMAN	ZBTB21	physical	27173435
CING_HUMAN	CGN	physical	27173435
GGYF1_HUMAN	GIGYF1	physical	27173435
LRFN1_HUMAN	LRFN1	physical	27173435
MAST3_HUMAN	MAST3	physical	27173435
SRGP2_HUMAN	SRGAP2	physical	27173435
SI1L1_HUMAN	SIPA1L1	physical	27173435
RGPS2_HUMAN	RALGPS2	physical	27173435
NF1_HUMAN	NF1	physical	27173435
CBY1_HUMAN	CBY1	physical	27173435
LIMA1_HUMAN	LIMA1	physical	27173435
GGYF2_HUMAN	GIGYF2	physical	27173435
MAGI1_HUMAN	MAGI1	physical	27173435
TESK2_HUMAN	TESK2	physical	27173435
DCLK1_HUMAN	DCLK1	physical	27173435
HDAC4_HUMAN	HDAC4	physical	27173435
ZN638_HUMAN	ZNF638	physical	27173435
NADK_HUMAN	NADK	physical	27173435
LPIN3_HUMAN	LPIN3	physical	27173435
NGAP_HUMAN	RASAL2	physical	27173435
M3K21_HUMAN	KIAA1804	physical	27173435
SRS12_HUMAN	SRSF12	physical	27173435
SYDE1_HUMAN	SYDE1	physical	27173435
TIAM1_HUMAN	TIAM1	physical	27173435
AGAP1_HUMAN	AGAP1	physical	27173435
CDK16_HUMAN	CDK16	physical	27173435
KIF1C_HUMAN	KIF1C	physical	27173435
PKHA7_HUMAN	PLEKHA7	physical	27173435
INP5E_HUMAN	INPP5E	physical	27173435

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CAMP2_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1313 AND SER-1319, ANDMASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-599, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-464; SER-598; SER-599;SER-673; SER-931; SER-936; THR-988; THR-997; THR-1002; THR-1004;SER-1008; SER-1029; SER-1313 AND SER-1319, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-900 AND SER-1319, ANDMASS SPECTROMETRY.	18220336 [Abstract]
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-931; SER-936; SER-1313AND SER-1319, AND MASS SPECTROMETRY.	16964243 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1250, AND MASSSPECTROMETRY.	17081983 [Abstract]