dbPTM

TANC2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TANC2_HUMAN
UniProt AC	Q9HCD6
Protein Name	Protein TANC2
Gene Name	TANC2
Organism	Homo sapiens (Human).
Sequence Length	1990
Subcellular Localization
Protein Description
Protein Sequence	MFRNSLKMLLTGGKSSRKNRSSDGGSEEPPDRRQSSVDSRQSRSGQGGISTESDCAFEPDYAVPPLPVSEGDAEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGDQYSMEVQDENQTSAITQRISPCSTLTSSTASPPASSPCSTLPPISTNATAKDCSYGAVTSPTSTLESRDSGIIATLTSYSENVERTKYAGESSKELGSGGNIKPWQSQKSSMDSCLYRVDENMTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSMGGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNASVNQGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQPPSAHSSITSGSCPGTPEMRRRQEEAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQLTAYREQLLREPHLQSMLSLRSCVQDPMASFRRGVLEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLIVTVRTSLQEITKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGSIEGTLEWEDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQMQQPQQPPPPPQPQQQLPEEAEPEPQHEDIYSVQDIFEEEYLEQDVENVSIGLQTEARPSQGLPVIQSPPSSPPHRDSAYISSSPLGSHQVFDFRSSSSVGSPTRQTYQSTSPALSPTHQNSHYRPSPPHTSPAHQGGSYRFSPPPVGGQGKEYPSPPPSPLRRGPQYRASPPAESMSVYRSQSGSPVRYQQETSVSQLPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSPAVHSSTVIPTGAYGQVAHSMASKYQSSQGDIGVSQSRLVYQGSIGGIVGDGRPVQHVQASLSAGAICQHGGLTKEDLPQRPSSAYRGGVRYSQTPQIGRSQSASYYPVCHSKLDLERSSSQLGSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPTFRPSSSIQQMEIPLKPAYERSCDELSPVSPTQGGYPSEPTRSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVLSPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEDDYYSPHGMLANGSRGDLLERVSQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MFRNSLKMLLTG ---CCHHHHHHHHHC	25.72	29514088
11	Phosphorylation	NSLKMLLTGGKSSRK HHHHHHHHCCCCCCC	39.67	24532841
21	Phosphorylation	KSSRKNRSSDGGSEE CCCCCCCCCCCCCCC	42.02	28355574
22	Phosphorylation	SSRKNRSSDGGSEEP CCCCCCCCCCCCCCC	36.72	21815630
26	Phosphorylation	NRSSDGGSEEPPDRR CCCCCCCCCCCCCCC	44.29	30576142
35	Phosphorylation	EPPDRRQSSVDSRQS CCCCCCCCCCCCCCC	30.44	-
112	Phosphorylation	VQPGDQYSMEVQDEN ECCCCCCEEEECCCC	11.66	28555341
129	Phosphorylation	SAITQRISPCSTLTS HHCCEEECCCCCCCC	23.26	25159151
132	Phosphorylation	TQRISPCSTLTSSTA CEEECCCCCCCCCCC	29.81	24719451
133	Phosphorylation	QRISPCSTLTSSTAS EEECCCCCCCCCCCC	40.55	24719451
135	Phosphorylation	ISPCSTLTSSTASPP ECCCCCCCCCCCCCC	22.25	24719451
136	Phosphorylation	SPCSTLTSSTASPPA CCCCCCCCCCCCCCC	28.89	29449344
137	Phosphorylation	PCSTLTSSTASPPAS CCCCCCCCCCCCCCC	23.82	29449344
138	Phosphorylation	CSTLTSSTASPPASS CCCCCCCCCCCCCCC	30.81	29449344
140	Phosphorylation	TLTSSTASPPASSPC CCCCCCCCCCCCCCC	31.35	25159151
144	Phosphorylation	STASPPASSPCSTLP CCCCCCCCCCCCCCC	40.35	25159151
145	Phosphorylation	TASPPASSPCSTLPP CCCCCCCCCCCCCCC	31.84	25159151
148	Phosphorylation	PPASSPCSTLPPIST CCCCCCCCCCCCCCC	36.04	29449344
149	Phosphorylation	PASSPCSTLPPISTN CCCCCCCCCCCCCCC	50.42	29449344
163	Phosphorylation	NATAKDCSYGAVTSP CCCCCCCCCCCCCCC	36.41	23403867
164	Phosphorylation	ATAKDCSYGAVTSPT CCCCCCCCCCCCCCC	18.55	23403867
168	Phosphorylation	DCSYGAVTSPTSTLE CCCCCCCCCCCCCHH	28.58	30266825
169	Phosphorylation	CSYGAVTSPTSTLES CCCCCCCCCCCCHHC	21.41	29255136
171	Phosphorylation	YGAVTSPTSTLESRD CCCCCCCCCCHHCCC	33.83	30266825
172	Phosphorylation	GAVTSPTSTLESRDS CCCCCCCCCHHCCCC	34.09	30266825
173	Phosphorylation	AVTSPTSTLESRDSG CCCCCCCCHHCCCCC	36.70	30266825
176	Phosphorylation	SPTSTLESRDSGIIA CCCCCHHCCCCCEEE	44.49	23927012
179	Phosphorylation	STLESRDSGIIATLT CCHHCCCCCEEEEEE	30.68	30576142
184	Phosphorylation	RDSGIIATLTSYSEN CCCCEEEEEEECCCC	21.84	27080861
187	Phosphorylation	GIIATLTSYSENVER CEEEEEEECCCCHHH	29.76	30576142
188	Phosphorylation	IIATLTSYSENVERT EEEEEEECCCCHHHC	18.12	30576142
197	Phosphorylation	ENVERTKYAGESSKE CCHHHCCCCCCCCCC	21.16	29396449
201	Phosphorylation	RTKYAGESSKELGSG HCCCCCCCCCCCCCC	45.88	29396449
202	Phosphorylation	TKYAGESSKELGSGG CCCCCCCCCCCCCCC	26.33	29396449
203	Ubiquitination	KYAGESSKELGSGGN CCCCCCCCCCCCCCC	67.26	29967540
207	Phosphorylation	ESSKELGSGGNIKPW CCCCCCCCCCCCCCC	57.03	29396449
212	Acetylation	LGSGGNIKPWQSQKS CCCCCCCCCCHHCCC	44.17	7467705
216	Phosphorylation	GNIKPWQSQKSSMDS CCCCCCHHCCCCHHH	35.39	29396449
218	Ubiquitination	IKPWQSQKSSMDSCL CCCCHHCCCCHHHCE	50.15	29967540
220	Phosphorylation	PWQSQKSSMDSCLYR CCHHCCCCHHHCEEE	33.37	28348404
233	Phosphorylation	YRVDENMTASTYSLN EEECCCCCCCCCCCC	29.10	21945579
235	Phosphorylation	VDENMTASTYSLNKI ECCCCCCCCCCCCCC	20.79	21945579
236	Phosphorylation	DENMTASTYSLNKIP CCCCCCCCCCCCCCC	18.05	25849741
237	Phosphorylation	ENMTASTYSLNKIPE CCCCCCCCCCCCCCC	14.52	21945579
238	Phosphorylation	NMTASTYSLNKIPER CCCCCCCCCCCCCCC	26.09	21945579
249	Phosphorylation	IPERNLETVLSQSVQ CCCCCHHHHHHHCCC	29.88	30183078
252	O-linked_Glycosylation	RNLETVLSQSVQSIP CCHHHHHHHCCCCCC	18.97	31373491
252	Phosphorylation	RNLETVLSQSVQSIP CCHHHHHHHCCCCCC	18.97	25850435
254	O-linked_Glycosylation	LETVLSQSVQSIPLY HHHHHHHCCCCCCEE	20.81	31373491
254	Phosphorylation	LETVLSQSVQSIPLY HHHHHHHCCCCCCEE	20.81	25849741
257	Phosphorylation	VLSQSVQSIPLYLMP HHHHCCCCCCEEECC	24.82	27732954
268	Phosphorylation	YLMPRPNSVAATSSA EECCCCCCEECCCCC	18.80	25849741
272	Phosphorylation	RPNSVAATSSAHLED CCCCEECCCCCHHHH	17.30	27732954
273	Phosphorylation	PNSVAATSSAHLEDL CCCEECCCCCHHHHH	22.32	27732954
274	Phosphorylation	NSVAATSSAHLEDLA CCEECCCCCHHHHHH	18.49	27732954
282	Phosphorylation	AHLEDLAYLDEQRHT CHHHHHHHCCCCCCC	23.22	27732954
289	Phosphorylation	YLDEQRHTPLRTSLR HCCCCCCCCCHHHCC	26.63	26699800
293	Phosphorylation	QRHTPLRTSLRMPRQ CCCCCCHHHCCCCCC	39.53	23403867
294	Phosphorylation	RHTPLRTSLRMPRQS CCCCCHHHCCCCCCC	13.93	23403867
301	Phosphorylation	SLRMPRQSMGGARTQ HCCCCCCCCCCCCCH	22.22	26074081
324	Phosphorylation	PYRPPDISLKPLLFE CCCCCCCCCCEEEEE	37.41	20068231
381	Phosphorylation	FGKTAIISRLVALSC CCHHHHHHHHHHHHC	17.28	28348404
387	Phosphorylation	ISRLVALSCHGTRMR HHHHHHHHCCCHHHH	8.37	28348404
391	Phosphorylation	VALSCHGTRMRQIAS HHHHCCCHHHHHHHC	9.53	27251275
398	Phosphorylation	TRMRQIASDSPHASP HHHHHHHCCCCCCCC	40.00	29255136
400	Phosphorylation	MRQIASDSPHASPKH HHHHHCCCCCCCCCC	18.98	18388127
404	Phosphorylation	ASDSPHASPKHVDAN HCCCCCCCCCCCCCC	31.29	18388127
417	Phosphorylation	ANRELPLTQPPSAHS CCCCCCCCCCCCCCC	36.77	28450419
421	Phosphorylation	LPLTQPPSAHSSITS CCCCCCCCCCCCCCC	45.34	23898821
424	Phosphorylation	TQPPSAHSSITSGSC CCCCCCCCCCCCCCC	24.13	21712546
425	Phosphorylation	QPPSAHSSITSGSCP CCCCCCCCCCCCCCC	21.73	23898821
427	Phosphorylation	PSAHSSITSGSCPGT CCCCCCCCCCCCCCC	29.05	21712546
428	Phosphorylation	SAHSSITSGSCPGTP CCCCCCCCCCCCCCH	27.34	21712546
430	Phosphorylation	HSSITSGSCPGTPEM CCCCCCCCCCCCHHH	19.53	22617229
434	Phosphorylation	TSGSCPGTPEMRRRQ CCCCCCCCHHHHHHH	10.96	23401153
578	Phosphorylation	SWLKLIVTVRTSLQE HHHHHHHHHHHHHHH	9.40	20068231
587	Phosphorylation	RTSLQEITKLLPFHR HHHHHHHHHHHHHHH	18.19	22210691
637	Phosphorylation	LNGKMDNTTFGKLSS CCCCCCCCCHHHHHH	21.16	28851738
638	Phosphorylation	NGKMDNTTFGKLSSH CCCCCCCCHHHHHHH	36.32	28851738
641	Ubiquitination	MDNTTFGKLSSHLKT CCCCCHHHHHHHHHH	40.79	29967540
643	Phosphorylation	NTTFGKLSSHLKTLS CCCHHHHHHHHHHHC	21.14	28851738
644	Phosphorylation	TTFGKLSSHLKTLSQ CCHHHHHHHHHHHCC	43.19	19651622
673	Phosphorylation	KGYLVLKSSSYKVVP CCEEEEECCCCEEEE	21.98	30576142
674	Phosphorylation	GYLVLKSSSYKVVPV CEEEEECCCCEEEEE	35.78	23898821
675	Phosphorylation	YLVLKSSSYKVVPVS EEEEECCCCEEEEEC	35.74	23898821
676	Phosphorylation	LVLKSSSYKVVPVSL EEEECCCCEEEEECH	15.11	30576142
682	Phosphorylation	SYKVVPVSLSEVYLL CCEEEEECHHHEEEE	21.80	23898821
684	Phosphorylation	KVVPVSLSEVYLLQC EEEEECHHHEEEEEC	19.94	30576142
687	Phosphorylation	PVSLSEVYLLQCNMK EECHHHEEEEECCCC	9.53	28387310
697	Phosphorylation	QCNMKFPTQSSFDRV ECCCCCCCCCCHHHH	44.19	23898821
699	Phosphorylation	NMKFPTQSSFDRVMP CCCCCCCCCHHHHHH	35.14	23898821
700	Phosphorylation	MKFPTQSSFDRVMPL CCCCCCCCHHHHHHH	22.73	23898821
749	Phosphorylation	QQRMENLSMFLIKRR HHHHHCCCCHHHHCC	21.04	20068231
759	Phosphorylation	LIKRRDMTRMFVHPS HHHCCCCHHEECCHH	24.22	30387612
823	Ubiquitination	ILKAHIFKGLSKKVG HHHHHHHHCHHCHHC	59.34	-
854	Phosphorylation	GLSMALASLRNLYTP HHHHHHHHHHCCCCC	28.81	24719451
859	Phosphorylation	LASLRNLYTPNIKVS HHHHHCCCCCCCCEE	24.57	18083107
866	Phosphorylation	YTPNIKVSRLLILGG CCCCCCEEEEEEECC	16.53	22210691
1028	Phosphorylation	VERAQINSFDSLWGE HHHHHHHCHHHHHHH	31.87	20873877
1031	Phosphorylation	AQINSFDSLWGETAL HHHHCHHHHHHHHHH	24.82	20873877
1036	Phosphorylation	FDSLWGETALTAAAG HHHHHHHHHHHHHHC	24.03	20873877
1039	Phosphorylation	LWGETALTAAAGRGK HHHHHHHHHHHCCCH	16.28	20873877
1147	Phosphorylation	ACLKGHLSVVRSLVD HHHHCCHHHHHHHHH	16.94	20068231
1151	Phosphorylation	GHLSVVRSLVDNGAA CCHHHHHHHHHCCCC	22.57	20068231
1159	Phosphorylation	LVDNGAATDHADKNG HHHCCCCCCCCCCCC	27.99	20068231
1213	Phosphorylation	AVGCRNTSVVVTLLK HCCCCCCHHHHEEEC	19.23	28555341
1245	Phosphorylation	DIMIILLSKLMEEGD CHHHHHHHHHHHHCC	21.94	20068231
1284	Ubiquitination	EGFGEDLKTFRELKV CCCCCCHHHHHHHHH	58.92	29967540
1316	Acetylation	MAEEFATKALELKPK CHHHHHHHHHHCCCC	47.77	18604379
1434	Phosphorylation	LQTEARPSQGLPVIQ ECCCCCCCCCCCCCC	31.18	30266825
1442	Phosphorylation	QGLPVIQSPPSSPPH CCCCCCCCCCCCCCC	27.88	23401153
1445	Phosphorylation	PVIQSPPSSPPHRDS CCCCCCCCCCCCCCC	59.88	23401153
1446	Phosphorylation	VIQSPPSSPPHRDSA CCCCCCCCCCCCCCC	48.50	30266825
1452	Phosphorylation	SSPPHRDSAYISSSP CCCCCCCCCCEECCC	23.95	28464451
1454	Phosphorylation	PPHRDSAYISSSPLG CCCCCCCCEECCCCC	12.80	29255136
1456	Phosphorylation	HRDSAYISSSPLGSH CCCCCCEECCCCCCC	16.46	30266825
1457	Phosphorylation	RDSAYISSSPLGSHQ CCCCCEECCCCCCCC	26.81	25463755
1458	Phosphorylation	DSAYISSSPLGSHQV CCCCEECCCCCCCCE	19.84	29255136
1462	Phosphorylation	ISSSPLGSHQVFDFR EECCCCCCCCEEECC	20.59	22167270
1470	Phosphorylation	HQVFDFRSSSSVGSP CCEEECCCCCCCCCC	34.27	29396449
1471	Phosphorylation	QVFDFRSSSSVGSPT CEEECCCCCCCCCCC	23.52	29396449
1472	Phosphorylation	VFDFRSSSSVGSPTR EEECCCCCCCCCCCC	30.23	29396449
1473	Phosphorylation	FDFRSSSSVGSPTRQ EECCCCCCCCCCCCC	32.23	29396449
1476	Phosphorylation	RSSSSVGSPTRQTYQ CCCCCCCCCCCCCEE	22.42	26055452
1478	Phosphorylation	SSSVGSPTRQTYQST CCCCCCCCCCCEECC	36.79	25849741
1481	Phosphorylation	VGSPTRQTYQSTSPA CCCCCCCCEECCCCC	21.90	27732954
1482	Phosphorylation	GSPTRQTYQSTSPAL CCCCCCCEECCCCCC	7.66	27732954
1484	Phosphorylation	PTRQTYQSTSPALSP CCCCCEECCCCCCCC	22.05	27732954
1485	Phosphorylation	TRQTYQSTSPALSPT CCCCEECCCCCCCCC	24.17	27732954
1486	Phosphorylation	RQTYQSTSPALSPTH CCCEECCCCCCCCCC	17.27	27732954
1490	Phosphorylation	QSTSPALSPTHQNSH ECCCCCCCCCCCCCC	29.83	25849741
1492	Phosphorylation	TSPALSPTHQNSHYR CCCCCCCCCCCCCCC	32.49	27732954
1496	Phosphorylation	LSPTHQNSHYRPSPP CCCCCCCCCCCCCCC	18.48	27732954
1498	Phosphorylation	PTHQNSHYRPSPPHT CCCCCCCCCCCCCCC	24.84	27732954
1501	Phosphorylation	QNSHYRPSPPHTSPA CCCCCCCCCCCCCCC	41.90	27732954
1505	Phosphorylation	YRPSPPHTSPAHQGG CCCCCCCCCCCCCCC	42.03	27732954
1506	Phosphorylation	RPSPPHTSPAHQGGS CCCCCCCCCCCCCCC	19.63	27732954
1513	Phosphorylation	SPAHQGGSYRFSPPP CCCCCCCCCCCCCCC	21.69	27732954
1514	Phosphorylation	PAHQGGSYRFSPPPV CCCCCCCCCCCCCCC	20.96	23927012
1517	Phosphorylation	QGGSYRFSPPPVGGQ CCCCCCCCCCCCCCC	27.74	28387310
1528	Phosphorylation	VGGQGKEYPSPPPSP CCCCCCCCCCCCCCC	16.70	29255136
1530	Phosphorylation	GQGKEYPSPPPSPLR CCCCCCCCCCCCCCC	49.49	23401153
1534	Phosphorylation	EYPSPPPSPLRRGPQ CCCCCCCCCCCCCCC	42.19	30266825
1542	Phosphorylation	PLRRGPQYRASPPAE CCCCCCCCCCCCCHH	15.98	24245541
1543	Methylation	LRRGPQYRASPPAES CCCCCCCCCCCCHHH	24.28	115918169
1545	Phosphorylation	RGPQYRASPPAESMS CCCCCCCCCCHHHCC	23.55	29255136
1550	Phosphorylation	RASPPAESMSVYRSQ CCCCCHHHCCEEECC	20.61	23927012
1552	Phosphorylation	SPPAESMSVYRSQSG CCCHHHCCEEECCCC	25.85	28102081
1556	Phosphorylation	ESMSVYRSQSGSPVR HHCCEEECCCCCCCE	15.83	30576142
1558	Phosphorylation	MSVYRSQSGSPVRYQ CCEEECCCCCCCEEE	42.35	30576142
1560	Phosphorylation	VYRSQSGSPVRYQQE EEECCCCCCCEEEEE	26.01	23927012
1563	Asymmetric dimethylarginine	SQSGSPVRYQQETSV CCCCCCCEEEEECCH	27.25	-
1563	Methylation	SQSGSPVRYQQETSV CCCCCCCEEEEECCH	27.25	-
1564	Phosphorylation	QSGSPVRYQQETSVS CCCCCCEEEEECCHH	18.12	23403867
1568	Phosphorylation	PVRYQQETSVSQLPG CCEEEEECCHHHCCC	30.05	30266825
1569	Phosphorylation	VRYQQETSVSQLPGR CEEEEECCHHHCCCC	21.01	30266825
1571	Phosphorylation	YQQETSVSQLPGRPK EEEECCHHHCCCCCC	26.26	30266825
1576	Asymmetric dimethylarginine	SVSQLPGRPKSPLSK CHHHCCCCCCCCHHH	33.27	-
1576	Methylation	SVSQLPGRPKSPLSK CHHHCCCCCCCCHHH	33.27	-
1579	Phosphorylation	QLPGRPKSPLSKMAQ HCCCCCCCCHHHHCC	33.48	22167270
1582	Phosphorylation	GRPKSPLSKMAQRPY CCCCCCHHHHCCCCC	24.62	30266825
1583	Acetylation	RPKSPLSKMAQRPYQ CCCCCHHHHCCCCCC	46.03	7493279
1589	Phosphorylation	SKMAQRPYQMPQLPV HHHCCCCCCCCCCCC	21.45	21945579
1609	Ubiquitination	GLRLQPAKAQIVRSN CCCCCCCCHHHHHCC	47.72	29967540
1619	Phosphorylation	IVRSNQPSPAVHSST HHHCCCCCCCCCCCC	18.74	25159151
1644	Phosphorylation	AHSMASKYQSSQGDI HHHHHHHHHCCCCCC	15.90	27732954
1646	Phosphorylation	SMASKYQSSQGDIGV HHHHHHHCCCCCCCC	22.87	27732954
1647	O-linked_Glycosylation	MASKYQSSQGDIGVS HHHHHHCCCCCCCCC	23.74	31373491
1647	Phosphorylation	MASKYQSSQGDIGVS HHHHHHCCCCCCCCC	23.74	29507054
1663	Phosphorylation	SRLVYQGSIGGIVGD HHEEEEECCCCEECC	11.52	28348404
1680	Phosphorylation	PVQHVQASLSAGAIC CCCCHHHHHHCCCHH	13.03	27251275
1682	Phosphorylation	QHVQASLSAGAICQH CCHHHHHHCCCHHHC	23.35	27251275
1700	Methylation	TKEDLPQRPSSAYRG CHHHCCCCCCCCCCC	31.00	115918173
1702	Phosphorylation	EDLPQRPSSAYRGGV HHCCCCCCCCCCCCC	29.77	28555341
1703	Phosphorylation	DLPQRPSSAYRGGVR HCCCCCCCCCCCCCC	31.81	25627689
1705	Phosphorylation	PQRPSSAYRGGVRYS CCCCCCCCCCCCCCC	16.25	28555341
1706	Methylation	QRPSSAYRGGVRYSQ CCCCCCCCCCCCCCC	34.80	54559827
1710	Methylation	SAYRGGVRYSQTPQI CCCCCCCCCCCCCCC	28.76	115918177
1711	Phosphorylation	AYRGGVRYSQTPQIG CCCCCCCCCCCCCCC	11.61	28674419
1712	Phosphorylation	YRGGVRYSQTPQIGR CCCCCCCCCCCCCCC	19.60	28555341
1714	Phosphorylation	GGVRYSQTPQIGRSQ CCCCCCCCCCCCCCC	15.95	27732954
1720	Phosphorylation	QTPQIGRSQSASYYP CCCCCCCCCCCCCCC	24.23	28857561
1722	Phosphorylation	PQIGRSQSASYYPVC CCCCCCCCCCCCCCC	22.04	30183078
1724	Phosphorylation	IGRSQSASYYPVCHS CCCCCCCCCCCCCCC	30.37	23090842
1725	Phosphorylation	GRSQSASYYPVCHSK CCCCCCCCCCCCCCH	16.11	23090842
1726	Phosphorylation	RSQSASYYPVCHSKL CCCCCCCCCCCCCHH	6.16	28985074
1731	Phosphorylation	SYYPVCHSKLDLERS CCCCCCCCHHCHHHC	29.77	23090842
1738	Phosphorylation	SKLDLERSSSQLGSP CHHCHHHCHHCCCCC	25.60	30266825
1739	Phosphorylation	KLDLERSSSQLGSPD HHCHHHCHHCCCCCC	28.46	30266825
1740	Phosphorylation	LDLERSSSQLGSPDV HCHHHCHHCCCCCCH	30.58	23401153
1744	Phosphorylation	RSSSQLGSPDVSHLI HCHHCCCCCCHHHHH	26.90	25159151
1748	Phosphorylation	QLGSPDVSHLIRRPI CCCCCCHHHHHCCCC	21.69	29396449
1770	Methylation	KPHPPTPRPLLHSQS CCCCCCCCCCCCCCC	36.66	115918181
1775	Phosphorylation	TPRPLLHSQSVGLRF CCCCCCCCCCCCEEE	24.91	28270605
1777	Phosphorylation	RPLLHSQSVGLRFSP CCCCCCCCCCEEECC	22.59	23917254
1781	Methylation	HSQSVGLRFSPSSNS CCCCCCEEECCCCCC	24.86	115918185
1783	Phosphorylation	QSVGLRFSPSSNSIS CCCCEEECCCCCCCC	19.89	27732954
1785	Phosphorylation	VGLRFSPSSNSISST CCEEECCCCCCCCCC	40.74	27732954
1786	Phosphorylation	GLRFSPSSNSISSTS CEEECCCCCCCCCCC	37.67	27732954
1788	Phosphorylation	RFSPSSNSISSTSNL EECCCCCCCCCCCCC	26.29	28270605
1790	Phosphorylation	SPSSNSISSTSNLTP CCCCCCCCCCCCCCC	27.64	28270605
1791	Phosphorylation	PSSNSISSTSNLTPT CCCCCCCCCCCCCCC	33.90	27732954
1792	Phosphorylation	SSNSISSTSNLTPTF CCCCCCCCCCCCCCC	18.16	27732954
1793	Phosphorylation	SNSISSTSNLTPTFR CCCCCCCCCCCCCCC	31.61	27732954
1796	Phosphorylation	ISSTSNLTPTFRPSS CCCCCCCCCCCCCCC	25.24	27732954
1798	Phosphorylation	STSNLTPTFRPSSSI CCCCCCCCCCCCCCC	27.35	27732954
1816	Phosphorylation	EIPLKPAYERSCDEL CCCCCCCCCCCCCCC	22.02	29978859
1819	Phosphorylation	LKPAYERSCDELSPV CCCCCCCCCCCCCCC	17.61	21712546
1824	Phosphorylation	ERSCDELSPVSPTQG CCCCCCCCCCCCCCC	22.62	25159151
1827	Phosphorylation	CDELSPVSPTQGGYP CCCCCCCCCCCCCCC	26.13	25159151
1829	Phosphorylation	ELSPVSPTQGGYPSE CCCCCCCCCCCCCCC	32.13	21712546
1833	Phosphorylation	VSPTQGGYPSEPTRS CCCCCCCCCCCCCCC	15.48	30576142
1835	Phosphorylation	PTQGGYPSEPTRSRT CCCCCCCCCCCCCCC	47.96	28450419
1838	Phosphorylation	GGYPSEPTRSRTTPF CCCCCCCCCCCCCCC	36.91	28450419
1840	Phosphorylation	YPSEPTRSRTTPFMG CCCCCCCCCCCCCCC	36.14	26074081
1842	Phosphorylation	SEPTRSRTTPFMGII CCCCCCCCCCCCCEE	39.81	26074081
1843	Phosphorylation	EPTRSRTTPFMGIID CCCCCCCCCCCCEEE	17.26	26074081
1878	Phosphorylation	SSVDTVLSPTSPGNL EECCEEECCCCCCCC	23.07	28348404
1880	Phosphorylation	VDTVLSPTSPGNLPQ CCEEECCCCCCCCCC	44.15	28348404
1881	Phosphorylation	DTVLSPTSPGNLPQP CEEECCCCCCCCCCC	33.91	28348404
1890	Phosphorylation	GNLPQPESFSPPSSI CCCCCCCCCCCCCCC	37.39	26074081
1892	Phosphorylation	LPQPESFSPPSSISN CCCCCCCCCCCCCEE	45.22	26074081
1895	Phosphorylation	PESFSPPSSISNIAF CCCCCCCCCCEEEEE	43.62	26074081
1896	Phosphorylation	ESFSPPSSISNIAFY CCCCCCCCCEEEEEE	35.49	26074081
1898	Phosphorylation	FSPPSSISNIAFYNK CCCCCCCEEEEEEEC	24.91	26074081
1903	Phosphorylation	SISNIAFYNKTNNAQ CCEEEEEEECCCCCC	13.51	26074081
1906	Phosphorylation	NIAFYNKTNNAQNGH EEEEEECCCCCCCCC	30.02	26074081
1919	Phosphorylation	GHLLEDDYYSPHGML CCCCCCCCCCCCCHH	20.40	27259358
1920	Phosphorylation	HLLEDDYYSPHGMLA CCCCCCCCCCCCHHC	23.79	26356563
1921	Phosphorylation	LLEDDYYSPHGMLAN CCCCCCCCCCCHHCC	12.28	21712546
1928	N-linked_Glycosylation	SPHGMLANGSRGDLL CCCCHHCCCCHHHHH	45.04	UniProtKB CARBOHYD
1939	O-linked_Glycosylation	GDLLERVSQASSYPD HHHHHHHHHHHCCCC	26.67	31373491
1939	Phosphorylation	GDLLERVSQASSYPD HHHHHHHHHHHCCCC	26.67	22964224
1942	Phosphorylation	LERVSQASSYPDVKV HHHHHHHHCCCCCCH	23.83	28348404
1943	Phosphorylation	ERVSQASSYPDVKVA HHHHHHHCCCCCCHH	43.64	28348404
1948	Ubiquitination	ASSYPDVKVARTLPV HHCCCCCCHHHCCCH	37.24	29967540
1952	O-linked_Glycosylation	PDVKVARTLPVAQAY CCCCHHHCCCHHHHH	26.19	31373491
1952	Phosphorylation	PDVKVARTLPVAQAY CCCCHHHCCCHHHHH	26.19	28555341
1964	Phosphorylation	QAYQDNLYRQLSRDS HHHHHHHHHHHHCCC	11.54	23917254
1968	Phosphorylation	DNLYRQLSRDSRQGQ HHHHHHHHCCCCCCC	26.21	28102081
1971	Phosphorylation	YRQLSRDSRQGQTSP HHHHHCCCCCCCCCC	25.95	28102081
1976	Phosphorylation	RDSRQGQTSPIKPKR CCCCCCCCCCCCCCC	43.21	30266825
1977	Phosphorylation	DSRQGQTSPIKPKRP CCCCCCCCCCCCCCC	19.42	30266825

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TANC2_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TANC2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TANC2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KCTD3_HUMAN	KCTD3	physical	27173435
KI13B_HUMAN	KIF13B	physical	27173435
CING_HUMAN	CGN	physical	27173435
ZBT21_HUMAN	ZBTB21	physical	27173435
GGYF1_HUMAN	GIGYF1	physical	27173435
MARE1_HUMAN	MAPRE1	physical	27173435
LRFN1_HUMAN	LRFN1	physical	27173435
MAST3_HUMAN	MAST3	physical	27173435
SRGP2_HUMAN	SRGAP2	physical	27173435
RGPS2_HUMAN	RALGPS2	physical	27173435
SI1L1_HUMAN	SIPA1L1	physical	27173435
NF1_HUMAN	NF1	physical	27173435
CBY1_HUMAN	CBY1	physical	27173435
GGYF2_HUMAN	GIGYF2	physical	27173435

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TANC2_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1530 AND SER-1534, ANDMASS SPECTROMETRY.	19690332 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1457, AND MASSSPECTROMETRY.	17081983 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-169 AND SER-1827, ANDMASS SPECTROMETRY.	15302935 [Abstract]
"Robust phosphoproteomic profiling of tyrosine phosphorylation sitesfrom human T cells using immobilized metal affinity chromatography andtandem mass spectrometry."; Brill L.M., Salomon A.R., Ficarro S.B., Mukherji M., Stettler-Gill M.,Peters E.C.; Anal. Chem. 76:2763-2772(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1442 AND SER-1446, ANDMASS SPECTROMETRY.	15144186 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-171, AND MASSSPECTROMETRY.	19413330 [Abstract]