DEN4C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DEN4C_HUMAN
• UniProt AC: Q5VZ89
• Protein Name: DENN domain-containing protein 4C
• Gene Name: DENND4C
• Organism: Homo sapiens (Human).
• Sequence Length: 1909
• Subcellular Localization: Cytoplasmic vesicle membrane. Cell membrane. Cytoplasm, cytosol. Associates with SLC2A4/GLUT4 storage vesicles.
• Protein Description: Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin..
• Protein Sequence: MIEDKGPRVTDYFVVAGLTDTSTLLDQEINRLDTKSTGPKAPITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCEVILATPYGRCANVNNSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDYESFPLSESDVPLFCLPMGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTNKCICLLSHWPFFEAFRKFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAEDTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLAKRCYTNPPQWAKCLFSHCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTARIKPNAITYGYYNKVVLESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISGGQSDQGYGSKDELIKDDAEIHVPEEQAARELITKTKMQTEEVCDASAIVAKHSQPSPEPHSPTEPPAWGSSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNGDRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDSNSSEMAIMMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWNPEHRSSPVPEMLEESQELLEPVVDDVPKTTATVDTYESLLSDSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATECTGGKTPDSEDKLFSPVIARNLADEIESYMNLKSPLGSKSSSMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAVSRSKTFTGRFKQQTPSRTHKERSTSLSALVRSSPHGSLGSVVNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDEEETNRDYSFPAGLEDHILGENISPNTSISGLVPSELTQSNTSLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLEHKPVSSLAEPDLINFMDFPKHNQIITEETGSAVEPSDEIKRASGDVQTMKISSVPNSLSKRNVSLTRSHSVGGPLQNIDFTQRPFHGISTVSLPNSLQEVVDPLGKRPNPPPVSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNEGVQLPLSSLSQDSKLVYIQLLWDNINLHQEPREPLYVSWRNFNSEKKSSLLSEEQQETSTLVETIRQSIQHNNVLKPINLLSQQMKPGMKRQRSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSSEILERLQKIDAPPSASVEWCRKCFGAPLI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
34	Phosphorylation	QEINRLDTKSTGPKA HHHHHCCCCCCCCCC	16.12	30206219
36	Phosphorylation	INRLDTKSTGPKAPI HHHCCCCCCCCCCCC	7.55	30206219
37	Phosphorylation	NRLDTKSTGPKAPIT HHCCCCCCCCCCCCC	2.63	30206219
44	Phosphorylation	TGPKAPITDIAIIIK CCCCCCCCEEEEEEE	29.96	30206219
51	Ubiquitination	TDIAIIIKSAGETVP CEEEEEEECCCCCCC	45.41	21963094
51 (in isoform 1)	Ubiquitination	-	45.41	21890473
51 (in isoform 5)	Ubiquitination	-	45.41	21890473
60	Phosphorylation	AGETVPEGYTCVEAT CCCCCCCCEEEEECC	30.26	24719451
79	Phosphorylation	QANLNYGSLKSPELF HHHCCCCCCCCCEEE	2.52	28060719
154	Phosphorylation	PPVRPQNSLAVTDIC CCCCCCCCCEEEEEE	32.02	30631047
158	Phosphorylation	PQNSLAVTDICVIVT CCCCCEEEEEEEEEE	20.25	30631047
250	Phosphorylation	CWDPETKYPLPVFST EECCCCCCCCCEEEE	1.69	32142685
256	Phosphorylation	KYPLPVFSTFVLTGS CCCCCEEEEEEEECC	20.37	28348404
257	Phosphorylation	YPLPVFSTFVLTGSS CCCCEEEEEEEECCC	2.87	28348404
261	Phosphorylation	VFSTFVLTGSSAKKV EEEEEEEECCCHHHH	26.88	28348404
263	Phosphorylation	STFVLTGSSAKKVYG EEEEEECCCHHHHHE	59.43	28348404
270	Acetylation	SSAKKVYGAAIQFYE CCHHHHHEEEEHHCC	36.63	-
274	Acetylation	KVYGAAIQFYEPYSR HHHEEEEHHCCCCCH	77.32	-
285	Acetylation	PYSRELLSEKQLMHL CCCHHHCCHHHHHHC	40.60	25953088
285	Phosphorylation	PYSRELLSEKQLMHL CCCHHHCCHHHHHHC	40.60	24719451
287	Ubiquitination	SRELLSEKQLMHLGL CHHHCCHHHHHHCCC	7.83	21963094
288	Phosphorylation	RELLSEKQLMHLGLL HHHCCHHHHHHCCCC	9.60	-
292	Phosphorylation	SEKQLMHLGLLTPVE CHHHHHHCCCCCHHH	25.68	-
296	Phosphorylation	LMHLGLLTPVERKMV HHHCCCCCHHHHHHH	48.62	24719451
313	Phosphorylation	SINTNKCICLLSHWP CCCCCCEEHHHCCCH	11.73	32142685
376	Phosphorylation	QLSVHDALILSQPVS EEEECCEEECCCCCC	15.95	-
421	Phosphorylation	LESKILLHSLRPAVL HHHHHHHHHCCHHHH	46.62	32142685
432	Phosphorylation	PAVLTGVAEAVVAMI HHHHHHHHHHHHHHH	33.29	32142685
444	Phosphorylation	AMIFPFQWQCPYIPL HHHCCCCCCCCCCCC	38.89	25627689
457	Phosphorylation	PLCPLSLAAVLSAPL CCCHHHHHHHHCCCC	65.65	32645325
463	Phosphorylation	LAAVLSAPLPFIVGV HHHHHCCCCCEEEEE	32.53	32142685
467	Phosphorylation	LSAPLPFIVGVDSRY HCCCCCEEEEECCCC	29.49	26074081
494	Phosphorylation	IDLDTNMLYVSDEKK EECCCCEEEECHHHC	28.78	24719451
495	Phosphorylation	DLDTNMLYVSDEKKN ECCCCEEEECHHHCC	21.39	32142685
498	Phosphorylation	TNMLYVSDEKKNMNW CCEEEECHHHCCCCH	42.76	20068231
501	Phosphorylation	LYVSDEKKNMNWKQL EEECHHHCCCCHHHC	32.74	20068231
503	Phosphorylation	VSDEKKNMNWKQLPK ECHHHCCCCHHHCCC	25.87	23911959
505	Phosphorylation	DEKKNMNWKQLPKKP HHHCCCCHHHCCCCH	24.09	23911959
506	Acetylation	EKKNMNWKQLPKKPC HHCCCCHHHCCCCHH	27.83	7339589
510	Acetylation	MNWKQLPKKPCKNLL CCHHHCCCCHHHHHH	13.08	90549
519	Phosphorylation	PCKNLLSTLKKLYPQ HHHHHHHHHHHHHHH	39.39	-
520	Phosphorylation	CKNLLSTLKKLYPQL HHHHHHHHHHHHHHH	7.88	32645325
524	Phosphorylation	LSTLKKLYPQLSSVH HHHHHHHHHHHHHHH	11.31	23898821
528	Phosphorylation	KKLYPQLSSVHQKTQ HHHHHHHHHHHHHCC	17.37	23898821
529	Phosphorylation	KLYPQLSSVHQKTQE HHHHHHHHHHHHCCC	44.89	23898821
538	Phosphorylation	HQKTQEGSAIDMTPI HHHCCCCCCCCCCCC	4.93	28857561
543	Phosphorylation	EGSAIDMTPIEADFS CCCCCCCCCCCCCCC	11.02	22210691
550	Phosphorylation	TPIEADFSWQKKMTQ CCCCCCCCHHHHHHH	2.02	22210691
556	Phosphorylation	FSWQKKMTQLEMEIQ CCHHHHHHHHHHHHH	4.38	29083192
572	Phosphorylation	AFLRFMASILKGYRT HHHHHHHHHHCHHHH	3.11	24719451
579	Phosphorylation	SILKGYRTYLRPITE HHHCHHHHHCCCCCC	11.19	32142685
591	Ubiquitination	ITEAPSNKATAADSL CCCCCCCCCCHHHHH	2.00	-
603	Phosphorylation	DSLFDRQGFLKSRDR HHHHHCCCCHHHHHH	6.31	32142685
612	Phosphorylation	LKSRDRAYAKFYTLL HHHHHHHHHHHHHHH	21.62	-
616	Acetylation	DRAYAKFYTLLSKTQ HHHHHHHHHHHHHHH	27.02	26051181
620	Phosphorylation	AKFYTLLSKTQIFIR HHHHHHHHHHHHHHH	3.76	24719451
628	Phosphorylation	KTQIFIRFIEECSFV HHHHHHHHHHHCCCC	5.45	32645325
632	Phosphorylation	FIRFIEECSFVSDKD HHHHHHHCCCCCCCC	28.27	-
637	Phosphorylation	EECSFVSDKDTGLAF HHCCCCCCCCCCEEC	24.62	-
645	Phosphorylation	KDTGLAFFDDCIEKL CCCCEECHHHHHHHH	5.39	32142685
651	Ubiquitination	FFDDCIEKLFPDKGT CHHHHHHHHCCCCCC	1.86	-
668	Phosphorylation	TDKVDFDSAEDTRLI CCCCCCCCCCCCEEE	25.39	27732954
669	Phosphorylation	DKVDFDSAEDTRLIE CCCCCCCCCCCEEEE	20.17	-
670	Phosphorylation	KVDFDSAEDTRLIEL CCCCCCCCCCEEEEC	41.10	32645325
672	Phosphorylation	DFDSAEDTRLIELDD CCCCCCCCEEEECCC	17.83	25627689
673	Phosphorylation	FDSAEDTRLIELDDS CCCCCCCEEEECCCC	23.16	25627689
675	Phosphorylation	SAEDTRLIELDDSQK CCCCCEEEECCCCCC	38.53	-
680	Phosphorylation	RLIELDDSQKSEHTV EEEECCCCCCCCCEE	37.73	21815630
683	Phosphorylation	ELDDSQKSEHTVFIM ECCCCCCCCCEEEEC	16.76	23312004
686	Phosphorylation	DSQKSEHTVFIMPPE CCCCCCCEEEECCCC	51.35	23312004
703	Phosphorylation	PDDGKDLSPKYSYKY CCCCCCCCCCCCCCC	16.27	21712546
706	Phosphorylation	GKDLSPKYSYKYFPR CCCCCCCCCCCCCCC	39.54	26074081
707	Phosphorylation	KDLSPKYSYKYFPRL CCCCCCCCCCCCCCC	5.13	26074081
708	Phosphorylation	DLSPKYSYKYFPRLD CCCCCCCCCCCCCCC	2.96	26074081
709	Phosphorylation	LSPKYSYKYFPRLDL CCCCCCCCCCCCCCC	45.33	-
711	Phosphorylation	PKYSYKYFPRLDLKL CCCCCCCCCCCCCEE	24.09	-
717	Ubiquitination	YFPRLDLKLFDRPQE CCCCCCCEECCCCHH	52.40	-
729	Phosphorylation	PQELKLCFSRHPTGN CHHHHHHHCCCCCCC	42.98	23663014
730	Phosphorylation	QELKLCFSRHPTGNS HHHHHHHCCCCCCCC	42.06	26074081
732	Phosphorylation	LKLCFSRHPTGNSIT HHHHHCCCCCCCCCC	33.97	17081983
734	Phosphorylation	LCFSRHPTGNSITKS HHHCCCCCCCCCCCC	61.04	23927012
737	Phosphorylation	SRHPTGNSITKSPPL CCCCCCCCCCCCCCC	44.20	23401153
739	Phosphorylation	HPTGNSITKSPPLMA CCCCCCCCCCCCCHH	65.23	23927012
740	Ubiquitination	PTGNSITKSPPLMAK CCCCCCCCCCCCHHH	53.31	-
741	Phosphorylation	TGNSITKSPPLMAKR CCCCCCCCCCCHHHC	26.79	22167270
746	Phosphorylation	TKSPPLMAKRTKQEI CCCCCCHHHCCHHHH	13.24	-
753	Phosphorylation	AKRTKQEIKTAHKLA HHCCHHHHHHHHHHH	47.73	20058876
755	Phosphorylation	RTKQEIKTAHKLAKR CCHHHHHHHHHHHHH	2.90	-
760	Phosphorylation	IKTAHKLAKRCYTNP HHHHHHHHHHHCCCC	40.72	25850435
761	Phosphorylation	KTAHKLAKRCYTNPP HHHHHHHHHHCCCCH	37.36	32142685
763	Phosphorylation	AHKLAKRCYTNPPQW HHHHHHHHCCCCHHH	31.83	23663014
764	Phosphorylation	HKLAKRCYTNPPQWA HHHHHHHCCCCHHHH	39.56	23898821
765	Phosphorylation	KLAKRCYTNPPQWAK HHHHHHCCCCHHHHH	41.88	23663014
767	Phosphorylation	AKRCYTNPPQWAKCL HHHHCCCCHHHHHHH	23.96	23663014
769	Phosphorylation	RCYTNPPQWAKCLFS HHCCCCHHHHHHHHH	23.68	23663014
774	Phosphorylation	PPQWAKCLFSHCYSL CHHHHHHHHHHHHHH	22.46	20873877
775	Phosphorylation	PQWAKCLFSHCYSLW HHHHHHHHHHHHHHH	29.65	20873877
780	Phosphorylation	CLFSHCYSLWFICLP HHHHHHHHHHHHHHH	45.71	32142685
786	Phosphorylation	YSLWFICLPAYVRVS HHHHHHHHHHHHHCC	40.64	32645325
788	Phosphorylation	LWFICLPAYVRVSHP HHHHHHHHHHHCCCH	36.46	23663014
800	Dimethylation	SHPKVRALQQAYDVL CCHHHHHHHHHHHHH	46.61	-
808	Phosphorylation	QQAYDVLIKMRKTDV HHHHHHHHHCCCCCC	16.67	23836654
810	Phosphorylation	AYDVLIKMRKTDVDP HHHHHHHCCCCCCCH	29.43	20363803
812	Phosphorylation	DVLIKMRKTDVDPLD HHHHHCCCCCCCHHH	19.53	-
813	Phosphorylation	VLIKMRKTDVDPLDE HHHHCCCCCCCHHHH	37.27	-
815	Phosphorylation	IKMRKTDVDPLDEVC HHCCCCCCCHHHHHH	29.40	32142685
824	Phosphorylation	PLDEVCYRVVMQLCG HHHHHHHHHHHHHHC	34.25	23090842
825	Phosphorylation	LDEVCYRVVMQLCGL HHHHHHHHHHHHHCH	45.11	25627689
828	Phosphorylation	VCYRVVMQLCGLWGH HHHHHHHHHHCHHCC	43.86	23090842
830	Phosphorylation	YRVVMQLCGLWGHPV HHHHHHHHCHHCCHH	31.46	25627689
831	Phosphorylation	RVVMQLCGLWGHPVL HHHHHHHCHHCCHHH	35.32	24702127
845	Phosphorylation	LAVRVLFEMKTARIK HHHHHHHHHCCCCCC	17.23	23403867
847	Ubiquitination	VRVLFEMKTARIKPN HHHHHHHCCCCCCCC	9.73	33845483
849	Phosphorylation	VLFEMKTARIKPNAI HHHHHCCCCCCCCCE	23.26	23403867
854	Phosphorylation	KTARIKPNAITYGYY CCCCCCCCCEEEEEE	34.75	24719451
861	Phosphorylation	NAITYGYYNKVVLES CCEEEEEECEEEEEC	16.92	21406692
863	Phosphorylation	ITYGYYNKVVLESPW EEEEEECEEEEECCC	33.37	23911959
868	Phosphorylation	YNKVVLESPWPSSTR ECEEEEECCCCCCCC	13.85	28555341
872	Phosphorylation	VLESPWPSSTRSGIF EEECCCCCCCCCCEE	17.54	25072903
873	Phosphorylation	LESPWPSSTRSGIFL EECCCCCCCCCCEEH	58.05	25072903
874	Phosphorylation	ESPWPSSTRSGIFLW ECCCCCCCCCCEEHH	27.78	25072903
876	Phosphorylation	PWPSSTRSGIFLWTK CCCCCCCCCEEHHHH	19.26	23898821
879	Phosphorylation	SSTRSGIFLWTKVRN CCCCCCEEHHHHHHH	30.46	-
882	Phosphorylation	RSGIFLWTKVRNVVR CCCEEHHHHHHHHHH	25.80	24719451
889	Phosphorylation	TKVRNVVRGLAQFRQ HHHHHHHHHHHHHHC	40.68	19690332
890	Phosphorylation	KVRNVVRGLAQFRQP HHHHHHHHHHHHHCH	29.85	19690332
899	Phosphorylation	AQFRQPLKKTVQRSQ HHHHCHHHHHHHHHH	21.41	24667141
905	Phosphorylation	LKKTVQRSQVSSISG HHHHHHHHHCCCCCC	31.25	21712546
908	Phosphorylation	TVQRSQVSSISGGQS HHHHHHCCCCCCCCC	51.96	25159151
909	Phosphorylation	VQRSQVSSISGGQSD HHHHHCCCCCCCCCC	47.19	25159151
910	Ubiquitination	QRSQVSSISGGQSDQ HHHHCCCCCCCCCCC	4.54	33845483
911	Phosphorylation	RSQVSSISGGQSDQG HHHCCCCCCCCCCCC	34.96	21712546
913	Phosphorylation	QVSSISGGQSDQGYG HCCCCCCCCCCCCCC	18.65	32142685
917 (in isoform 7)	Phosphorylation	-	4.86	30177828
920	Phosphorylation	GQSDQGYGSKDELIK CCCCCCCCCHHHHHC	10.08	-
920 (in isoform 7)	Phosphorylation	-	10.08	30177828
922	Phosphorylation	SDQGYGSKDELIKDD CCCCCCCHHHHHCCC	24.97	-
924	Phosphorylation	QGYGSKDELIKDDAE CCCCCHHHHHCCCCC	8.12	-
924 (in isoform 7)	Phosphorylation	-	8.12	18669648
924	Phosphorylation	QGYGSKDELIKDDAE CCCCCHHHHHCCCCC	8.12	-
926 (in isoform 7)	Phosphorylation	-	52.38	30177828
927	Phosphorylation	GSKDELIKDDAEIHV CCHHHHHCCCCCCCC	38.49	25627689
928	Phosphorylation	SKDELIKDDAEIHVP CHHHHHCCCCCCCCC	50.39	32142685
929	Phosphorylation	KDELIKDDAEIHVPE HHHHHCCCCCCCCCH	39.95	-
929 (in isoform 7)	Phosphorylation	-	39.95	30177828
929	Phosphorylation	KDELIKDDAEIHVPE HHHHHCCCCCCCCCH	39.95	-
932	Phosphorylation	LIKDDAEIHVPEEQA HHCCCCCCCCCHHHH	31.82	-
932 (in isoform 7)	Phosphorylation	-	31.82	18669648
932	Phosphorylation	LIKDDAEIHVPEEQA HHCCCCCCCCCHHHH	31.82	-
933 (in isoform 7)	Phosphorylation	-	43.44	30177828
938	Phosphorylation	EIHVPEEQAARELIT CCCCCHHHHHHHHHH	6.82	32645325
942 (in isoform 7)	Phosphorylation	-	8.16	30177828
945	Phosphorylation	QAARELITKTKMQTE HHHHHHHHHHHCCHH	47.42	-
947	Phosphorylation	ARELITKTKMQTEEV HHHHHHHHHCCHHHH	26.72	24719451
948	Phosphorylation	RELITKTKMQTEEVC HHHHHHHHCCHHHHH	29.64	23911959
950	Phosphorylation	LITKTKMQTEEVCDA HHHHHHCCHHHHHCH	14.40	20068231
953	Phosphorylation	KTKMQTEEVCDASAI HHHCCHHHHHCHHHH	8.33	23663014
953 (in isoform 7)	Phosphorylation	-	8.33	23927012
953	Phosphorylation	KTKMQTEEVCDASAI HHHCCHHHHHCHHHH	8.33	23663014
958	Phosphorylation	TEEVCDASAIVAKHS HHHHHCHHHHHHCCC	30.39	25627689
958 (in isoform 7)	Phosphorylation	-	30.39	25627689
958	Phosphorylation	TEEVCDASAIVAKHS HHHHHCHHHHHHCCC	30.39	25627689
959 (in isoform 7)	Phosphorylation	-	49.68	22496350
960 (in isoform 7)	Phosphorylation	-	45.82	23927012
964 (in isoform 7)	Phosphorylation	-	17.99	23927012
965	Phosphorylation	SAIVAKHSQPSPEPH HHHHHCCCCCCCCCC	8.83	22167270
968	Phosphorylation	VAKHSQPSPEPHSPT HHCCCCCCCCCCCCC	5.86	22167270
968 (in isoform 7)	Phosphorylation	-	5.86	23927012
970	Phosphorylation	KHSQPSPEPHSPTEP CCCCCCCCCCCCCCC	5.06	23898821
970 (in isoform 7)	Phosphorylation	-	5.06	23898821
970	Phosphorylation	KHSQPSPEPHSPTEP CCCCCCCCCCCCCCC	5.06	23898821
973	Phosphorylation	QPSPEPHSPTEPPAW CCCCCCCCCCCCCCC	31.40	22167270
975	Phosphorylation	SPEPHSPTEPPAWGS CCCCCCCCCCCCCCC	3.58	22167270
976	Phosphorylation	PEPHSPTEPPAWGSS CCCCCCCCCCCCCCC	42.61	25849741
980	Phosphorylation	SPTEPPAWGSSIVKV CCCCCCCCCCCCEEC	35.29	23403867
982	Phosphorylation	TEPPAWGSSIVKVPS CCCCCCCCCCEECCC	70.64	23927012
983	Phosphorylation	EPPAWGSSIVKVPSG CCCCCCCCCEECCCC	49.23	23927012
989	Phosphorylation	SSIVKVPSGIFDVNS CCCEECCCCCEECCC	28.79	19664994
991	Phosphorylation	IVKVPSGIFDVNSRK CEECCCCCEECCCCC	5.32	32142685
996	Phosphorylation	SGIFDVNSRKSSTGS CCCEECCCCCCCCCC	5.46	30266825
997	Phosphorylation	GIFDVNSRKSSTGSI CCEECCCCCCCCCCC	18.88	32142685
999	Phosphorylation	FDVNSRKSSTGSISN EECCCCCCCCCCCCE	42.94	30278072
1000	Phosphorylation	DVNSRKSSTGSISNV ECCCCCCCCCCCCEE	4.36	30278072
1001	Phosphorylation	VNSRKSSTGSISNVL CCCCCCCCCCCCEEE	33.50	30278072
1002	Phosphorylation	NSRKSSTGSISNVLF CCCCCCCCCCCEEEE	35.03	23090842
1003	Phosphorylation	SRKSSTGSISNVLFS CCCCCCCCCCEEEEC	4.17	30278072
1005	Phosphorylation	KSSTGSISNVLFSTQ CCCCCCCCEEEECCC	35.76	30278072
1007	Methylation	STGSISNVLFSTQDP CCCCCCEEEECCCCH	45.05	-
1008	Phosphorylation	TGSISNVLFSTQDPV CCCCCEEEECCCCHH	28.64	25849741
1010	Phosphorylation	SISNVLFSTQDPVED CCCEEEECCCCHHHH	18.26	30278072
1011	Phosphorylation	ISNVLFSTQDPVEDA CCEEEECCCCHHHHC	36.09	30278072
1012	Phosphorylation	SNVLFSTQDPVEDAV CEEEECCCCHHHHCH	36.73	18669648
1014	Phosphorylation	VLFSTQDPVEDAVFG EEECCCCHHHHCHHH	29.37	24719451
1016	Phosphorylation	FSTQDPVEDAVFGEA ECCCCHHHHCHHHCC	24.30	25849741
1018	Ubiquitination	TQDPVEDAVFGEATN CCCHHHHCHHHCCCC	43.29	33845483
1022	Phosphorylation	VEDAVFGEATNLKKN HHHCHHHCCCCCHHC	49.21	32645325
1024	Phosphorylation	DAVFGEATNLKKNGD HCHHHCCCCCHHCCC	48.55	23663014
1027	Phosphorylation	FGEATNLKKNGDRGE HHCCCCCHHCCCCCH	30.54	24719451
1041	Phosphorylation	EKRQKHFPERSCSFS HHHHHHCCCCCCCCC	42.31	23663014
1042	Phosphorylation	KRQKHFPERSCSFSS HHHHHCCCCCCCCCC	31.99	23911959
1044	Phosphorylation	QKHFPERSCSFSSES HHHCCCCCCCCCCHH	37.38	21815630
1046	Phosphorylation	HFPERSCSFSSESRA HCCCCCCCCCCHHHH	42.01	23401153
1048	Phosphorylation	PERSCSFSSESRAGM CCCCCCCCCHHHHHH	34.68	25106551
1049	Phosphorylation	ERSCSFSSESRAGML CCCCCCCCHHHHHHH	17.40	21712546
1051	Phosphorylation	SCSFSSESRAGMLLK CCCCCCHHHHHHHEH	30.89	30242111
1057	Phosphorylation	ESRAGMLLKKSSLDS HHHHHHHEHHHHCCC	52.13	20363803
1060	Phosphorylation	AGMLLKKSSLDSNSS HHHHEHHHHCCCCCH	37.19	25159151
1060	Ubiquitination	AGMLLKKSSLDSNSS HHHHEHHHHCCCCCH	37.19	33845483
1061	Phosphorylation	GMLLKKSSLDSNSSE HHHEHHHHCCCCCHH	28.13	25159151
1064	Phosphorylation	LKKSSLDSNSSEMAI EHHHHCCCCCHHHHH	5.77	21712546
1065	Phosphorylation	KKSSLDSNSSEMAIM HHHHCCCCCHHHHHH	32.70	23090842
1066	Phosphorylation	KSSLDSNSSEMAIMM HHHCCCCCHHHHHHH	35.26	25159151
1067	Phosphorylation	SSLDSNSSEMAIMMG HHCCCCCHHHHHHHC	28.65	21712546
1069	Phosphorylation	LDSNSSEMAIMMGAD CCCCCHHHHHHHCCC	27.89	24719451
1075	Acetylation	EMAIMMGADAKILTA HHHHHHCCCHHHHHH	39.89	-
1078	Phosphorylation	IMMGADAKILTAALT HHHCCCHHHHHHHHH	22.27	24719451
1081	Phosphorylation	GADAKILTAALTCPK CCCHHHHHHHHHCCC	41.89	20860994
1085	Phosphorylation	KILTAALTCPKTSLL HHHHHHHHCCCCHHH	44.23	23403867
1087	Phosphorylation	LTAALTCPKTSLLHI HHHHHHCCCCHHHHH	24.36	24961811
1088	Phosphorylation	TAALTCPKTSLLHIA HHHHHCCCCHHHHHH	39.65	24719451
1089	Phosphorylation	AALTCPKTSLLHIAR HHHHCCCCHHHHHHC	22.90	19664994
1090	Phosphorylation	ALTCPKTSLLHIART HHHCCCCHHHHHHCC	3.34	29802988
1091	Phosphorylation	LTCPKTSLLHIARTH HHCCCCHHHHHHCCC	21.23	14729942
1096	Phosphorylation	TSLLHIARTHSFENV CHHHHHHCCCCCCCE	40.52	20068231
1097	Phosphorylation	SLLHIARTHSFENVS HHHHHHCCCCCCCEE	15.45	23927012
1099	Phosphorylation	LHIARTHSFENVSCH HHHHCCCCCCCEEEE	40.18	25159151
1101	Phosphorylation	IARTHSFENVSCHLP HHCCCCCCCEEEECC	26.90	18669648
1104	Phosphorylation	THSFENVSCHLPDSR CCCCCCEEEECCCCC	28.34	23927012
1108	Phosphorylation	ENVSCHLPDSRTCMS CCEEEECCCCCCCCC	16.59	23898821
1110	Phosphorylation	VSCHLPDSRTCMSES EEEECCCCCCCCCCC	41.73	23927012
1112	Phosphorylation	CHLPDSRTCMSESTW EECCCCCCCCCCCCC	4.47	23312004
1115	Phosphorylation	PDSRTCMSESTWNPE CCCCCCCCCCCCCHH	38.24	25106551
1117	Phosphorylation	SRTCMSESTWNPEHR CCCCCCCCCCCHHHC	3.02	28348404
1118	Phosphorylation	RTCMSESTWNPEHRS CCCCCCCCCCHHHCC	6.41	24719451
1119	Phosphorylation	TCMSESTWNPEHRSS CCCCCCCCCHHHCCC	49.61	25627689
1125	Phosphorylation	TWNPEHRSSPVPEML CCCHHHCCCCCHHHH	9.15	22167270
1126	Phosphorylation	WNPEHRSSPVPEMLE CCHHHCCCCCHHHHH	3.03	22167270
1128	Phosphorylation	PEHRSSPVPEMLEES HHHCCCCCHHHHHHH	39.70	24719451
1135	Phosphorylation	VPEMLEESQELLEPV CHHHHHHHHHHHHHH	21.44	22167270
1138	Phosphorylation	MLEESQELLEPVVDD HHHHHHHHHHHHCCC	20.78	-
1149	Phosphorylation	VVDDVPKTTATVDTY HCCCCCCCCEEHHHH	20.20	29978859
1150	Phosphorylation	VDDVPKTTATVDTYE CCCCCCCCEEHHHHH	11.93	29978859
1151	Phosphorylation	DDVPKTTATVDTYES CCCCCCCEEHHHHHH	32.42	-
1152	Phosphorylation	DVPKTTATVDTYESL CCCCCCEEHHHHHHH	60.14	29978859
1155	Phosphorylation	KTTATVDTYESLLSD CCCEEHHHHHHHHCC	76.69	29978859
1156	Phosphorylation	TTATVDTYESLLSDS CCEEHHHHHHHHCCC	49.70	28796482
1158	Phosphorylation	ATVDTYESLLSDSNS EEHHHHHHHHCCCCC	37.80	29978859
1161	Phosphorylation	DTYESLLSDSNSNQS HHHHHHHCCCCCCCC	14.69	29978859
1163	Phosphorylation	YESLLSDSNSNQSRD HHHHHCCCCCCCCCC	3.80	25159151
1165	Phosphorylation	SLLSDSNSNQSRDLK HHHCCCCCCCCCCHH	32.94	21712546
1176	Ubiquitination	RDLKTVSKDLRNKRS CCHHHHCHHHHHHHH	6.70	33845483
1183	Phosphorylation	KDLRNKRSSLYGIAK HHHHHHHHHHHHHHH	26.33	23401153
1184	Phosphorylation	DLRNKRSSLYGIAKV HHHHHHHHHHHHHHH	29.08	22167270
1186	Phosphorylation	RNKRSSLYGIAKVVQ HHHHHHHHHHHHHHC	5.82	30266825
1199	Phosphorylation	VQREDVETGLDPLSL HCHHHHCCCCCHHHH	32.13	27080861
1202	Phosphorylation	EDVETGLDPLSLLAT HHHCCCCCHHHHHHE	40.04	26074081
1205	Phosphorylation	ETGLDPLSLLATECT CCCCCHHHHHHEECC	48.20	28450419
1209	Phosphorylation	DPLSLLATECTGGKT CHHHHHHEECCCCCC	3.73	28387310
1211	Phosphorylation	LSLLATECTGGKTPD HHHHHEECCCCCCCC	16.96	25627689
1212	Phosphorylation	SLLATECTGGKTPDS HHHHEECCCCCCCCC	24.15	25849741
1215	Ubiquitination	ATECTGGKTPDSEDK HEECCCCCCCCCHHH	49.88	-
1216	Phosphorylation	TECTGGKTPDSEDKL EECCCCCCCCCHHHC	6.65	25159151
1219	Phosphorylation	TGGKTPDSEDKLFSP CCCCCCCCHHHCCHH	26.33	21712546
1225	Phosphorylation	DSEDKLFSPVIARNL CCHHHCCHHHHHHHH	46.86	19664994
1230	Phosphorylation	LFSPVIARNLADEIE CCHHHHHHHHHHHHH	27.87	-
1238	Phosphorylation	NLADEIESYMNLKSP HHHHHHHHHCCCCCC	20.40	27794612
1239	Phosphorylation	LADEIESYMNLKSPL HHHHHHHHCCCCCCC	24.98	27794612
1243	Methylation	IESYMNLKSPLGSKS HHHHCCCCCCCCCCC	3.00	-
1244	Phosphorylation	ESYMNLKSPLGSKSS HHHCCCCCCCCCCCC	8.81	22617229
1248	Phosphorylation	NLKSPLGSKSSSMEL CCCCCCCCCCCCCHH	12.53	22617229
1249	Ubiquitination	LKSPLGSKSSSMELH CCCCCCCCCCCCHHC	3.89	-
1250	Phosphorylation	KSPLGSKSSSMELHR CCCCCCCCCCCHHCH	17.61	23403867
1251	Phosphorylation	SPLGSKSSSMELHRE CCCCCCCCCCHHCHH	3.31	23403867
1252	Phosphorylation	PLGSKSSSMELHREE CCCCCCCCCHHCHHH	1.43	23401153
1254	Phosphorylation	GSKSSSMELHREENR CCCCCCCHHCHHHHH	24.83	-
1263	Phosphorylation	HREENRESGMTTAFI CHHHHHHHCHHHHHH	22.44	30624053
1266	Phosphorylation	ENRESGMTTAFIHAL HHHHHCHHHHHHHHH	5.85	30624053
1267	Phosphorylation	NRESGMTTAFIHALE HHHHCHHHHHHHHHH	20.63	30624053
1277	Phosphorylation	IHALERRSSLPLDHG HHHHHHHCCCCCCCC	16.47	29255136
1278	Phosphorylation	HALERRSSLPLDHGS HHHHHHCCCCCCCCC	53.12	29255136
1285	Phosphorylation	SLPLDHGSPAQENPE CCCCCCCCCCCCCCC	9.64	29255136
1293	Phosphorylation	PAQENPESEKSSPAV CCCCCCCCCCCCCCC	10.83	23401153
1295	Ubiquitination	QENPESEKSSPAVSR CCCCCCCCCCCCCCC	30.57	-
1296	Phosphorylation	ENPESEKSSPAVSRS CCCCCCCCCCCCCCC	6.60	23401153
1297	Phosphorylation	NPESEKSSPAVSRSK CCCCCCCCCCCCCCC	5.99	22167270
1301	Phosphorylation	EKSSPAVSRSKTFTG CCCCCCCCCCCCCCC	7.08	22167270
1303	Phosphorylation	SSPAVSRSKTFTGRF CCCCCCCCCCCCCCC	47.09	26699800
1304	Ubiquitination	SPAVSRSKTFTGRFK CCCCCCCCCCCCCCC	7.42	-
1305	Phosphorylation	PAVSRSKTFTGRFKQ CCCCCCCCCCCCCCC	47.34	26657352
1311	Acetylation	KTFTGRFKQQTPSRT CCCCCCCCCCCCCCC	8.75	19822955
1314	Phosphorylation	TGRFKQQTPSRTHKE CCCCCCCCCCCCHHH	45.01	24719451
1315	Phosphorylation	GRFKQQTPSRTHKER CCCCCCCCCCCHHHH	33.35	20068231
1316	Phosphorylation	RFKQQTPSRTHKERS CCCCCCCCCCHHHHC	45.30	20068231
1317	Phosphorylation	FKQQTPSRTHKERST CCCCCCCCCHHHHCC	44.96	20068231
1318	Phosphorylation	KQQTPSRTHKERSTS CCCCCCCCHHHHCCC	28.72	30576142
1320	Phosphorylation	QTPSRTHKERSTSLS CCCCCCHHHHCCCHH	31.65	26074081
1323	Phosphorylation	SRTHKERSTSLSALV CCCHHHHCCCHHHHH	39.54	30266825
1324	Phosphorylation	RTHKERSTSLSALVR CCHHHHCCCHHHHHH	19.34	30266825
1325	Phosphorylation	THKERSTSLSALVRS CHHHHCCCHHHHHHC	26.70	19664994
1327	Phosphorylation	KERSTSLSALVRSSP HHHCCCHHHHHHCCC	27.41	30266825
1328	Ubiquitination	ERSTSLSALVRSSPH HHCCCHHHHHHCCCC	8.34	33845483
1332	Phosphorylation	SLSALVRSSPHGSLG CHHHHHHCCCCCCHH	38.57	25159151
1333	Phosphorylation	LSALVRSSPHGSLGS HHHHHHCCCCCCHHH	6.97	25159151
1337	Phosphorylation	VRSSPHGSLGSVVNS HHCCCCCCHHHHHHH	32.88	25159151
1340	Phosphorylation	SPHGSLGSVVNSLSG CCCCCHHHHHHHCCC	31.65	25159151
1343	Ubiquitination	GSLGSVVNSLSGLKL CCHHHHHHHCCCCCC	44.64	33845483
1344	Phosphorylation	SLGSVVNSLSGLKLD CHHHHHHHCCCCCCC	35.78	21712546
1346	Phosphorylation	GSVVNSLSGLKLDNI HHHHHHCCCCCCCHH	5.16	25159151
1349	Ubiquitination	VNSLSGLKLDNILSG HHHCCCCCCCHHCCC	3.84	-
1355	Phosphorylation	LKLDNILSGPKIDVL CCCCHHCCCCCHHHH	31.50	25159151
1358	Ubiquitination	DNILSGPKIDVLKSG CHHCCCCCHHHHHHH	5.23	-
1363	Phosphorylation	GPKIDVLKSGMKQAA CCCHHHHHHHHHHHH	30.15	-
1363	Ubiquitination	GPKIDVLKSGMKQAA CCCHHHHHHHHHHHH	30.15	33845483
1364	Phosphorylation	PKIDVLKSGMKQAAT CCHHHHHHHHHHHHH	19.52	29214152
1365	Phosphorylation	KIDVLKSGMKQAATV CHHHHHHHHHHHHHH	36.24	23911959
1367	Ubiquitination	DVLKSGMKQAATVAS HHHHHHHHHHHHHHH	13.73	-
1371	Phosphorylation	SGMKQAATVASKMWV HHHHHHHHHHHHHHH	72.81	-
1374	Phosphorylation	KQAATVASKMWVAVA HHHHHHHHHHHHHHH	39.60	-
1377	Phosphorylation	ATVASKMWVAVASAY HHHHHHHHHHHHHHC	39.29	25849741
1382	Phosphorylation	KMWVAVASAYSYSDD HHHHHHHHHCCCCCC	21.93	28060719
1384	Phosphorylation	WVAVASAYSYSDDEE HHHHHHHCCCCCCCH	42.71	28060719
1385	Phosphorylation	VAVASAYSYSDDEEE HHHHHHCCCCCCCHH	2.29	28060719
1386	Phosphorylation	AVASAYSYSDDEEET HHHHHCCCCCCCHHC	21.55	28060719
1387	Phosphorylation	VASAYSYSDDEEETN HHHHCCCCCCCHHCC	45.10	27362937
1391	Phosphorylation	YSYSDDEEETNRDYS CCCCCCCHHCCCCCC	28.13	18669648
1393	Phosphorylation	YSDDEEETNRDYSFP CCCCCHHCCCCCCCC	29.41	20068231
1398	Phosphorylation	EETNRDYSFPAGLED HHCCCCCCCCCCCCC	27.80	24719451
1402	Phosphorylation	RDYSFPAGLEDHILG CCCCCCCCCCCHHCC	18.19	18669648
1404	Phosphorylation	YSFPAGLEDHILGEN CCCCCCCCCHHCCCC	24.57	18669648
1406	Ubiquitination	FPAGLEDHILGENIS CCCCCCCHHCCCCCC	34.71	33845483
1412	Ubiquitination	DHILGENISPNTSIS CHHCCCCCCCCCCCC	2.73	33845483
1415	Phosphorylation	LGENISPNTSISGLV CCCCCCCCCCCCCCC	21.66	-
1423	Phosphorylation	TSISGLVPSELTQSN CCCCCCCCCHHCCCC	27.61	25627689
1424	Phosphorylation	SISGLVPSELTQSNT CCCCCCCCHHCCCCC	16.52	25627689
1426	Phosphorylation	SGLVPSELTQSNTSL CCCCCCHHCCCCCCC	37.89	25850435
1430	Phosphorylation	PSELTQSNTSLGSSS CCHHCCCCCCCCCCC	29.50	23898821
1435	Phosphorylation	QSNTSLGSSSSSGDV CCCCCCCCCCCCCCC	6.54	26074081
1436	Phosphorylation	SNTSLGSSSSSGDVG CCCCCCCCCCCCCCC	37.57	26074081
1437	Phosphorylation	NTSLGSSSSSGDVGK CCCCCCCCCCCCCCC	31.25	26074081
1438	Phosphorylation	TSLGSSSSSGDVGKL CCCCCCCCCCCCCCC	12.51	26074081
1439	Phosphorylation	SLGSSSSSGDVGKLH CCCCCCCCCCCCCCC	29.34	26074081
1447	Phosphorylation	GDVGKLHYPTGEVPF CCCCCCCCCCCCCCC	12.73	25627689
1449	Phosphorylation	VGKLHYPTGEVPFPR CCCCCCCCCCCCCCC	3.53	28555341
1466	Phosphorylation	KGQDFEKSDHGSSQN CCCCCCCCCCCCCCC	59.54	-
1490	Phosphorylation	CAMEVLMSSCSQCRA HHHHHHHHHHHHCCC	3.35	-
1527	Phosphorylation	TACPFCKSNFLPLLN CCCHHHHHCCEEEEC	21.91	-
1543	Phosphorylation	EFKDLRGSASFFLKP EEECCCCCEEEEECC	66.60	28270605
1545	Phosphorylation	KDLRGSASFFLKPST ECCCCCEEEEECCCC	39.09	28270605
1550	Phosphorylation	SASFFLKPSTSGDSL CEEEEECCCCCCCCC	11.80	-
1551	Phosphorylation	ASFFLKPSTSGDSLQ EEEEECCCCCCCCCC	6.11	20068231
1552	Phosphorylation	SFFLKPSTSGDSLQS EEEECCCCCCCCCCC	13.53	20068231
1553	Phosphorylation	FFLKPSTSGDSLQSG EEECCCCCCCCCCCC	6.81	20068231
1556	Phosphorylation	KPSTSGDSLQSGSIP CCCCCCCCCCCCCCC	8.81	29507054
1559	Phosphorylation	TSGDSLQSGSIPLAN CCCCCCCCCCCCCCC	66.66	29496963
1561	Phosphorylation	GDSLQSGSIPLANES CCCCCCCCCCCCCCC	41.02	28464451
1562	Phosphorylation	DSLQSGSIPLANESL CCCCCCCCCCCCCCC	36.97	20166139
1563	Phosphorylation	SLQSGSIPLANESLE CCCCCCCCCCCCCCC	42.06	24275569
1566	Phosphorylation	SGSIPLANESLEHKP CCCCCCCCCCCCCCC	44.36	-
1568	Phosphorylation	SIPLANESLEHKPVS CCCCCCCCCCCCCCC	54.94	28464451
1572	Phosphorylation	ANESLEHKPVSSLAE CCCCCCCCCCCCCCC	23.75	-
1575	Phosphorylation	SLEHKPVSSLAEPDL CCCCCCCCCCCCCCC	3.08	27251275
1576	Phosphorylation	LEHKPVSSLAEPDLI CCCCCCCCCCCCCCC	6.54	27251275
1578	Phosphorylation	HKPVSSLAEPDLINF CCCCCCCCCCCCCCC	17.61	22798277
1596	Phosphorylation	PKHNQIITEETGSAV CCCCCEECCCCCCCC	22.87	22798277
1599	Phosphorylation	NQIITEETGSAVEPS CCEECCCCCCCCCCC	4.36	27732954
1601	Phosphorylation	IITEETGSAVEPSDE EECCCCCCCCCCCHH	42.65	26657352
1606	Phosphorylation	TGSAVEPSDEIKRAS CCCCCCCCHHHHHCC	33.52	30624053
1610	Ubiquitination	VEPSDEIKRASGDVQ CCCCHHHHHCCCCCE	13.88	-
1613	Phosphorylation	SDEIKRASGDVQTMK CHHHHHCCCCCEEEE	2.14	23927012
1618	Phosphorylation	RASGDVQTMKISSVP HCCCCCEEEEEECCC	3.10	29978859
1622	Phosphorylation	DVQTMKISSVPNSLS CCEEEEEECCCCCHH	27.61	30266825
1623	Phosphorylation	VQTMKISSVPNSLSK CEEEEEECCCCCHHC	38.80	30266825
1627	Phosphorylation	KISSVPNSLSKRNVS EEECCCCCHHCCCCC	44.23	30266825
1629	Phosphorylation	SSVPNSLSKRNVSLT ECCCCCHHCCCCCCC	39.26	25159151
1630	Ubiquitination	SVPNSLSKRNVSLTR CCCCCHHCCCCCCCC	19.89	-
1634	Phosphorylation	SLSKRNVSLTRSHSV CHHCCCCCCCCCCCC	47.16	29496963
1636	Phosphorylation	SKRNVSLTRSHSVGG HCCCCCCCCCCCCCC	7.59	28102081
1638	Phosphorylation	RNVSLTRSHSVGGPL CCCCCCCCCCCCCCC	7.97	23401153
1640	Phosphorylation	VSLTRSHSVGGPLQN CCCCCCCCCCCCCCC	27.70	23401153
1651	Phosphorylation	PLQNIDFTQRPFHGI CCCCCCCCCCCCCCC	47.05	26657352
1659	Phosphorylation	QRPFHGISTVSLPNS CCCCCCCEEECCCCH	24.30	25159151
1660	Phosphorylation	RPFHGISTVSLPNSL CCCCCCEEECCCCHH	25.55	25159151
1662	Phosphorylation	FHGISTVSLPNSLQE CCCCEEECCCCHHHH	38.06	25159151
1666	Phosphorylation	STVSLPNSLQEVVDP EEECCCCHHHHHHCC	30.68	26657352
1757	Phosphorylation	EGVQLPLSSLSQDSK CCCCCCHHHCCCCCC		24275569
1763	Phosphorylation	LSSLSQDSKLVYIQL HHHCCCCCCEEEEEH		-
1786	Phosphorylation	QEPREPLYVSWRNFN CCCCCCCCCEECCCC		28796482
1788	Phosphorylation	PREPLYVSWRNFNSE CCCCCCCEECCCCHH		29978859
1794	Phosphorylation	VSWRNFNSEKKSSLL CEECCCCHHHHHHCC		27050516
1797	Ubiquitination	RNFNSEKKSSLLSEE CCCCHHHHHHCCCHH		-
1798	Phosphorylation	NFNSEKKSSLLSEEQ CCCHHHHHHCCCHHH		21712546
1799	Phosphorylation	FNSEKKSSLLSEEQQ CCHHHHHHCCCHHHH		21712546
1802	Phosphorylation	EKKSSLLSEEQQETS HHHHHCCCHHHHHHH		21712546
1808	Phosphorylation	LSEEQQETSTLVETI CCHHHHHHHHHHHHH		28450419
1809	Phosphorylation	SEEQQETSTLVETIR CHHHHHHHHHHHHHH		28450419
1810	Phosphorylation	EEQQETSTLVETIRQ HHHHHHHHHHHHHHH		28060719
1814	Phosphorylation	ETSTLVETIRQSIQH HHHHHHHHHHHHHHC		22798277
1826	Ubiquitination	IQHNNVLKPINLLSQ HHCCCCCHHHHHHHH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DEN4C_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DEN4C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DEN4C_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KCTD3_HUMAN	KCTD3	physical	27173435
KI13B_HUMAN	KIF13B	physical	27173435
ZBT21_HUMAN	ZBTB21	physical	27173435
GGYF1_HUMAN	GIGYF1	physical	27173435
CING_HUMAN	CGN	physical	27173435
LRFN1_HUMAN	LRFN1	physical	27173435
DEN1A_HUMAN	DENND1A	physical	27173435
RTKN_HUMAN	RTKN	physical	27173435
MAST3_HUMAN	MAST3	physical	27173435
SRGP2_HUMAN	SRGAP2	physical	27173435
SI1L1_HUMAN	SIPA1L1	physical	27173435
PPM1H_HUMAN	PPM1H	physical	27173435
LPIN3_HUMAN	LPIN3	physical	27173435
LIMA1_HUMAN	LIMA1	physical	27173435
MAGI1_HUMAN	MAGI1	physical	27173435
TESK2_HUMAN	TESK2	physical	27173435
DCLK1_HUMAN	DCLK1	physical	27173435
ZN638_HUMAN	ZNF638	physical	27173435
SIN1_HUMAN	MAPKAP1	physical	27173435
NF1_HUMAN	NF1	physical	27173435
HDAC4_HUMAN	HDAC4	physical	27173435
CBY1_HUMAN	CBY1	physical	27173435
SRS12_HUMAN	SRSF12	physical	27173435
MPIP3_HUMAN	CDC25C	physical	27173435
SYDE1_HUMAN	SYDE1	physical	27173435
AGAP1_HUMAN	AGAP1	physical	27173435
NADK_HUMAN	NADK	physical	27173435
GGYF2_HUMAN	GIGYF2	physical	27173435
MPIP2_HUMAN	CDC25B	physical	27173435
CDK16_HUMAN	CDK16	physical	27173435
TANC2_HUMAN	TANC2	physical	27173435
PTN13_HUMAN	PTPN13	physical	27173435
CAMP2_HUMAN	CAMSAP2	physical	27173435
RGPS2_HUMAN	RALGPS2	physical	27173435
F110B_HUMAN	FAM110B	physical	27173435
UBP21_HUMAN	USP21	physical	27173435
M3K21_HUMAN	KIAA1804	physical	27173435
NGAP_HUMAN	RASAL2	physical	27173435
TIAM1_HUMAN	TIAM1	physical	27173435
FA53C_HUMAN	FAM53C	physical	27173435
AN34A_HUMAN	ANKRD34A	physical	27173435
OSBL6_HUMAN	OSBPL6	physical	27173435
RPTOR_HUMAN	RPTOR	physical	27173435
PKHA7_HUMAN	PLEKHA7	physical	27173435
KIF1C_HUMAN	KIF1C	physical	27173435
KC1A_HUMAN	CSNK1A1	physical	27173435
MELK_HUMAN	MELK	physical	27173435
NAV1_HUMAN	NAV1	physical	27173435
F110A_HUMAN	FAM110A	physical	27173435
GAB2_HUMAN	GAB2	physical	27173435
STA13_HUMAN	STARD13	physical	27173435
PTN14_HUMAN	PTPN14	physical	27173435
WEE1_HUMAN	WEE1	physical	27173435
INP5E_HUMAN	INPP5E	physical	27173435

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-737; SER-753; SER-1042;SER-1089 AND SER-1110, AND MASS SPECTROMETRY.
PubMed: 19690332

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-753; SER-989; SER-1089;SER-1317 AND SER-1320, AND MASS SPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-505; SER-729; SER-732;SER-737; SER-753; THR-765; SER-767; SER-810; SER-863; SER-890;SER-989; SER-1008; SER-1089; SER-1387 AND SER-1391, AND MASSSPECTROMETRY.
PubMed: 18669648

"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization.";
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
Nat. Biotechnol. 24:1285-1292(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1089, AND MASSSPECTROMETRY.
PubMed: 16964243

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-863, AND MASSSPECTROMETRY.
PubMed: 17081983