STA13_HUMAN - dbPTM
STA13_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID STA13_HUMAN
UniProt AC Q9Y3M8
Protein Name StAR-related lipid transfer protein 13
Gene Name STARD13
Organism Homo sapiens (Human).
Sequence Length 1113
Subcellular Localization Cytoplasm. Membrane
Peripheral membrane protein
Cytoplasmic side. Mitochondrion membrane
Peripheral membrane protein
Cytoplasmic side. Lipid droplet.
Protein Description GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells..
Protein Sequence MFSQVPRTPASGCYYLNSMTPEGQEMYLRFDQTTRRSPYRMSRILARHQLVTKIQQEIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVKNDHDFLEKDLVEPLCRRLNTLNKCASMKLDVNFQRKKGDDSDEEDLCISNKWTFQRTSRRWSRVDDLYTLLPRGDRNGSPGGTGMRNTTSSESVLTDLSEPEVCSIHSESSGGSDSRSQPGQCCTDNPVMLDAPLVSSSLPQPPRDVLNHPFHPKNEKPTRARAKSFLKRMETLRGKGAHGRHKGSGRTGGLVISGPMLQQEPESFKAMQCIQIPNGDLQNSPPPACRKGLPCSGKSSGESSPSEHSSSGVSTPCLKERKCHEANKRGGMYLEDLDVLAGTALPDAGDQSRMHEFHSQENLVVHIPKDHKPGTFPKALSIESLSPTDSSNGVNWRTGSISLGREQVPGAREPRLMASCHRASRVSIYDNVPGSHLYASTGDLLDLEKDDLFPHLDDILQHVNGLQEVVDDWSKDVLPELQTHDTLVGEPGLSTFPSPNQITLDFEGNSVSEGRTTPSDVERDVTSLNESEPPGVRDRRDSGVGASLTRPNRRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFHTYLNHLIQGLQKEAKEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERHLWDEDFVQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVEHEEAQLLGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVARIRNSFQPLIAEGPETKI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
1Acetylation-------MFSQVPRT
-------CCCCCCCC		34.0022814378
3Phosphorylation-----MFSQVPRTPA
-----CCCCCCCCCC		41.9724719451
8PhosphorylationMFSQVPRTPASGCYY
CCCCCCCCCCCCCEE		19.6924719451
11PhosphorylationQVPRTPASGCYYLNS
CCCCCCCCCCEEECC		30.5124719451
15 (in isoform 3)Phosphorylation-11.9525849741
18PhosphorylationSGCYYLNSMTPEGQE
CCCEEECCCCCCCCE		22.8022199227
20PhosphorylationCYYLNSMTPEGQEMY
CEEECCCCCCCCEEE		20.2922199227
37PhosphorylationFDQTTRRSPYRMSRI
CCCCCCCCHHHHHHH		24.0029214152
39PhosphorylationQTTRRSPYRMSRILA
CCCCCCHHHHHHHHH		21.86-
42PhosphorylationRRSPYRMSRILARHQ
CCCHHHHHHHHHHHH		13.73-
75PhosphorylationRAAGFPQYAQLYEDS
HHCCCCHHHHHHCCC		9.1427642862
79PhosphorylationFPQYAQLYEDSQFPI
CCHHHHHHCCCCCCE		12.9527642862
100UbiquitinationNDHDFLEKDLVEPLC
CCCHHHHHHCHHHHH		59.51-
118PhosphorylationNTLNKCASMKLDVNF
HHHHHHHCCCCCCCE		26.39-
133PhosphorylationQRKKGDDSDEEDLCI
ECCCCCCCCHHHCCC		52.2229255136
141PhosphorylationDEEDLCISNKWTFQR
CHHHCCCCCCCHHHC		31.2123403867
154PhosphorylationQRTSRRWSRVDDLYT
HCCCCCCCCHHHHHH		22.1822199227
160PhosphorylationWSRVDDLYTLLPRGD
CCCHHHHHHHCCCCC		11.4425106551
161PhosphorylationSRVDDLYTLLPRGDR
CCHHHHHHHCCCCCC		29.1729978859
171PhosphorylationPRGDRNGSPGGTGMR
CCCCCCCCCCCCCCC		24.7429255136
175PhosphorylationRNGSPGGTGMRNTTS
CCCCCCCCCCCCCCC		33.4528102081
180PhosphorylationGGTGMRNTTSSESVL
CCCCCCCCCCCCCHH		20.0728348404
181PhosphorylationGTGMRNTTSSESVLT
CCCCCCCCCCCCHHC		33.5325850435
182PhosphorylationTGMRNTTSSESVLTD
CCCCCCCCCCCHHCC		30.0325850435
183PhosphorylationGMRNTTSSESVLTDL
CCCCCCCCCCHHCCC		31.6228348404
185PhosphorylationRNTTSSESVLTDLSE
CCCCCCCCHHCCCCC		25.1128348404
188PhosphorylationTSSESVLTDLSEPEV
CCCCCHHCCCCCCCE		32.5123312004
191PhosphorylationESVLTDLSEPEVCSI
CCHHCCCCCCCEEEE		54.6523312004
197PhosphorylationLSEPEVCSIHSESSG
CCCCCEEEEECCCCC		28.6323312004
200PhosphorylationPEVCSIHSESSGGSD
CCEEEEECCCCCCCC		37.1923312004
202PhosphorylationVCSIHSESSGGSDSR
EEEEECCCCCCCCCC		36.9823312004
203PhosphorylationCSIHSESSGGSDSRS
EEEECCCCCCCCCCC		43.0223312004
206PhosphorylationHSESSGGSDSRSQPG
ECCCCCCCCCCCCCC		35.6223312004
208PhosphorylationESSGGSDSRSQPGQC
CCCCCCCCCCCCCCC		35.2123312004
247UbiquitinationLNHPFHPKNEKPTRA
HCCCCCCCCCCCCHH		69.99-
258PhosphorylationPTRARAKSFLKRMET
CCHHHHHHHHHHHHH		34.5224719451
265PhosphorylationSFLKRMETLRGKGAH
HHHHHHHHHCCCCCC		16.6529514088
267MethylationLKRMETLRGKGAHGR
HHHHHHHCCCCCCCC		52.8083108439
314PhosphorylationPNGDLQNSPPPACRK
CCCCCCCCCCCHHHC		26.3129255136
326PhosphorylationCRKGLPCSGKSSGES
HHCCCCCCCCCCCCC		47.5223663014
329PhosphorylationGLPCSGKSSGESSPS
CCCCCCCCCCCCCCC		47.2923663014
330PhosphorylationLPCSGKSSGESSPSE
CCCCCCCCCCCCCCC		50.4923663014
333PhosphorylationSGKSSGESSPSEHSS
CCCCCCCCCCCCCCC		51.5823663014
334PhosphorylationGKSSGESSPSEHSSS
CCCCCCCCCCCCCCC		28.3026657352
336PhosphorylationSSGESSPSEHSSSGV
CCCCCCCCCCCCCCC		50.3023663014
339PhosphorylationESSPSEHSSSGVSTP
CCCCCCCCCCCCCCH		23.3423090842
340PhosphorylationSSPSEHSSSGVSTPC
CCCCCCCCCCCCCHH		32.7823090842
341PhosphorylationSPSEHSSSGVSTPCL
CCCCCCCCCCCCHHH		46.3523090842
344PhosphorylationEHSSSGVSTPCLKER
CCCCCCCCCHHHHHH		30.1123090842
345PhosphorylationHSSSGVSTPCLKERK
CCCCCCCCHHHHHHH		18.6723090842
389PhosphorylationSRMHEFHSQENLVVH
CHHCEECCCCCEEEE		44.5029255136
411PhosphorylationGTFPKALSIESLSPT
CCCCCCEEEEECCCC		29.2130266825
414PhosphorylationPKALSIESLSPTDSS
CCCEEEEECCCCCCC		32.2630266825
416PhosphorylationALSIESLSPTDSSNG
CEEEEECCCCCCCCC		34.7223927012
418PhosphorylationSIESLSPTDSSNGVN
EEEECCCCCCCCCCC		45.1723403867
420PhosphorylationESLSPTDSSNGVNWR
EECCCCCCCCCCCCC		28.3423403867
421PhosphorylationSLSPTDSSNGVNWRT
ECCCCCCCCCCCCCC		40.1723403867
428PhosphorylationSNGVNWRTGSISLGR
CCCCCCCCCEEEECC		27.2226699800
430PhosphorylationGVNWRTGSISLGREQ
CCCCCCCEEEECCCC		14.3723911959
432PhosphorylationNWRTGSISLGREQVP
CCCCCEEEECCCCCC		26.8624275569
449PhosphorylationREPRLMASCHRASRV
CCCHHHHHCCCCCCC		9.1127251275
454PhosphorylationMASCHRASRVSIYDN
HHHCCCCCCCEEECC		32.9223090842
457PhosphorylationCHRASRVSIYDNVPG
CCCCCCCEEECCCCC		17.8323090842
459PhosphorylationRASRVSIYDNVPGSH
CCCCCEEECCCCCCC		8.2423090842
465PhosphorylationIYDNVPGSHLYASTG
EECCCCCCCEEEECC		12.3028450419
468PhosphorylationNVPGSHLYASTGDLL
CCCCCCEEEECCCCC		7.9629507054
470PhosphorylationPGSHLYASTGDLLDL
CCCCEEEECCCCCCC		21.2629743597
471PhosphorylationGSHLYASTGDLLDLE
CCCEEEECCCCCCCC		26.9229507054
524PhosphorylationLVGEPGLSTFPSPNQ
CCCCCCCCCCCCCCE		33.6429523821
525PhosphorylationVGEPGLSTFPSPNQI
CCCCCCCCCCCCCEE		44.6129523821
528PhosphorylationPGLSTFPSPNQITLD
CCCCCCCCCCEEEEE		32.0929523821
533PhosphorylationFPSPNQITLDFEGNS
CCCCCEEEEECCCCC		15.5429523821
546PhosphorylationNSVSEGRTTPSDVER
CCCCCCCCCHHHHHH		54.6524114839
547PhosphorylationSVSEGRTTPSDVERD
CCCCCCCCHHHHHHC		21.3121815630
549PhosphorylationSEGRTTPSDVERDVT
CCCCCCHHHHHHCHH		52.8024114839
556PhosphorylationSDVERDVTSLNESEP
HHHHHCHHCCCCCCC		31.6121888424
557PhosphorylationDVERDVTSLNESEPP
HHHHCHHCCCCCCCC		29.1028674419
572PhosphorylationGVRDRRDSGVGASLT
CCCCCCCCCCCCCCC		33.3030266825
577PhosphorylationRDSGVGASLTRPNRR
CCCCCCCCCCCCCCC		25.0929255136
579PhosphorylationSGVGASLTRPNRRLR
CCCCCCCCCCCCCCC		41.4029255136
589PhosphorylationNRRLRWNSFQLSHQP
CCCCCCCCEECCCCC		13.8630266825
640PhosphorylationMSNKHGWTWSVPKFM
CCCCCCCCCCHHHHH		16.6823403867
642PhosphorylationNKHGWTWSVPKFMKR
CCCCCCCCHHHHHHH		22.5923403867
828PhosphorylationLNLLKKESSPRVIQK
HHHHCCCCCCHHHHH		55.30-
829PhosphorylationNLLKKESSPRVIQKK
HHHCCCCCCHHHHHH		20.16-
930PhosphorylationEKFKGWVTCSSTDNT
HHHCCCEEECCCCCC		10.52-
942UbiquitinationDNTDLAFKKVGDGNP
CCCCEEEEECCCCCC		40.73-
1031PhosphorylationKGMCTLVSLSVEHEE
CCCEEEEEEEECHHH		20.3122210691
1033PhosphorylationMCTLVSLSVEHEEAQ
CEEEEEEEECHHHHH		20.2522210691
1054PhosphorylationAVVMDSQYLIEPCGS
EEEECCCEEEEECCC		17.3828509920
1067O-linked_GlycosylationGSGKSRLTHICRIDL
CCCCCCEEEEEEEEC		14.2130379171
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of STA13_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of STA13_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of STA13_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TBA1A_HUMANTUBA1Aphysical
14697242
KIF1B_HUMANKIF1Bphysical
14697242
HMDH_HUMANHMGCRphysical
14697242
E41L1_HUMANEPB41L1physical
14697242
SMRD3_HUMANSMARCD3physical
14697242
TAXB1_HUMANTAX1BP1physical
14697242
HS90A_HUMANHSP90AA1physical
14697242
ITPR1_HUMANITPR1physical
14697242
AGRB2_HUMANBAI2physical
14697242
S10A7_HUMANS100A7physical
28514442
SPB4_HUMANSERPINB4physical
28514442
KI13B_HUMANKIF13Bphysical
27173435
ZBT21_HUMANZBTB21physical
27173435
GGYF1_HUMANGIGYF1physical
27173435
CING_HUMANCGNphysical
27173435
LRFN1_HUMANLRFN1physical
27173435
SI1L1_HUMANSIPA1L1physical
27173435
LIMA1_HUMANLIMA1physical
27173435
MAGI1_HUMANMAGI1physical
27173435
TESK2_HUMANTESK2physical
27173435
DCLK1_HUMANDCLK1physical
27173435
HDAC4_HUMANHDAC4physical
27173435
CBY1_HUMANCBY1physical
27173435
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of STA13_HUMAN

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Related Literatures of Post-Translational Modification

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