KIF1B_HUMAN - dbPTM
KIF1B_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KIF1B_HUMAN
UniProt AC O60333
Protein Name Kinesin-like protein KIF1B
Gene Name KIF1B
Organism Homo sapiens (Human).
Sequence Length 1816
Subcellular Localization Cytoplasmic vesicle. Cytoplasm, cytoskeleton. Mitochondrion . Colocalizes with synaptophysin at synaptic cytoplasmic transport vesicles in the neurites of hippocampal neurons..
Protein Description Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility. Isoform 2 is required for induction of neuronal apoptosis..
Protein Sequence MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVDNCTSKSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDIDPLIDDYSGSGSKYLKDFQNNKHRYLLASENQRPGHFSTASMGSLTSSPSSCSLSSQVGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEMGVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERRQDIVLSGAHIKEEHCIFRSERSNSGEVIVTLEPCERSETYVNGKRVSQPVQLRSGNRIIMGKNHVFRFNHPEQARAEREKTPSAETPSEPVDWTFAQRELLEKQGIDMKQEMEKRLQEMEILYKKEKEEADLLLEQQRLDYESKLQALQKQVETRSLAAETTEEEEEEEEVPWTQHEFELAQWAFRKWKSHQFTSLRDLLWGNAVYLKEANAISVELKKKVQFQFVLLTDTLYSPLPPELLPTEMEKTHEDRPFPRTVVAVEVQDLKNGATHYWSLEKLKQRLDLMREMYDRAGEMASSAQDESETTVTGSDPFYDRFHWFKLVGSSPIFHGCVNERLADRTPSPTFSTADSDITELADEQQDEMEDFDDEAFVDDAGSDAGTEEGSDLFSDGHDPFYDRSPWFILVGRAFVYLSNLLYPVPLIHRVAIVSEKGEVRGFLRVAVQAIAADEEAPDYGSGIRQSGTAKISFDNEYFNQSDFSSVAMTRSGLSLEELRIVEGQGQSSEVITPPEEISRINDLDLKSSTLLDGKMVMEGFSEEIGNHLKLGSAFTFRVTVLQASGILPEYADIFCQFNFLHRHDEAFSTEPLKNNGRGSPLAFYHVQNIAVEITESFVDYIKTKPIVFEVFGHYQQHPLHLQGQELNSPPQPCRRFFPPPMPLSKPVPATKLNTMSKTSLGQSMSKYDLLVWFEISELEPTGEYIPAVVDHTAGLPCQGTFLLHQGIQRRITVTIIHEKGSELHWKDVRELVVGRIRNKPEVDEAAVDAILSLNIISAKYLKSSHNSSRTFYRFEAVWDSSLHNSLLLNRVTPYGEKIYMTLSAYLELDHCIQPAVITKDVCMVFYSRDAKISPPRSLRSLFGSGYSKSPDSNRVTGIYELSLCKMSDTGSPGMQRRRRKILDTSVAYVRGEENLAGWRPRGDSLILEHQWELEKLELLHEVEKTRHFLLLRERLGDSIPKSLSDSLSPSLSSGTLSTSTSISSQISTTTFESAITPSESSGYDSGDIESLVDREKELATKCLQLLTHTFNREFSQVHGSVSDCKLSDISPIGRDPSESSFSSATLTPSSTCPSLVDSRSNSLDQKTPEANSRASSPCPEFEQFQIVPAVETPYLARAGKNEFLNLVPDIEEIRPSSVVSKKGYLHFKEPLYSNWAKHFVVVRRPYVFIYNSDKDPVERGIINLSTAQVEYSEDQQAMVKTPNTFAVCTKHRGVLLQALNDKDMNDWLYAFNPLLAGTIRSKLSRRCPSQSKY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MSGASVKVA
------CCCCCEEEE		55.1322814378
7Acetylation-MSGASVKVAVRVRP
-CCCCCEEEEEEECC		23.21129877
11MethylationASVKVAVRVRPFNSR
CCEEEEEEECCCCCC		14.69115481153
139PhosphorylationDNCNEEMSYSVEVSY
CCCCCCCCEEEEEEE		19.9624043423
140PhosphorylationNCNEEMSYSVEVSYM
CCCCCCCEEEEEEEE		18.5424043423
141PhosphorylationCNEEMSYSVEVSYME
CCCCCCEEEEEEEEE		12.4224043423
145PhosphorylationMSYSVEVSYMEIYCE
CCEEEEEEEEEHHHH		12.7824043423
146PhosphorylationSYSVEVSYMEIYCER
CEEEEEEEEEHHHHH		12.1624043423
150PhosphorylationEVSYMEIYCERVRDL
EEEEEEHHHHHHHHH		3.8024043423
161UbiquitinationVRDLLNPKNKGNLRV
HHHHHCCCCCCCCCC		70.9432142685
188PhosphorylationLSKLAVTSYTDIADL
HHHHHCCCCCHHHHH		21.3130576142
243UbiquitinationLSTEKVSKISLVDLA
CCHHEEEEEEEEECC		39.0232015554
274PhosphorylationEGANINKSLTTLGKV
CCCCCCHHHHHHHHH		26.85-
276PhosphorylationANINKSLTTLGKVIS
CCCCHHHHHHHHHHH		27.37-
277PhosphorylationNINKSLTTLGKVISA
CCCHHHHHHHHHHHH		38.5129116813
292PhosphorylationLAEVDNCTSKSKKKK
HHHHCCCCCCCCCCC		45.5029116813
294UbiquitinationEVDNCTSKSKKKKKT
HHCCCCCCCCCCCCC		48.41-
301PhosphorylationKSKKKKKTDFIPYRD
CCCCCCCCCCCCCHH		45.0528555341
325PhosphorylationNLGGNSRTAMVAALS
CCCCCCCHHHEEECC		20.9427067055
332PhosphorylationTAMVAALSPADINYD
HHHEEECCHHHCCHH		17.2027067055
338PhosphorylationLSPADINYDETLSTL
CCHHHCCHHHHHHHH		18.5827067055
349UbiquitinationLSTLRYADRAKQIKC
HHHHHHHHHHHHCCC		41.9829967540
367UbiquitinationINEDPNAKLVRELKE
CCCCCCHHHHHHHHH		54.90-
389 (in isoform 2)Phosphorylation-30.7828348404
389 (in isoform 3)Phosphorylation-30.7828348404
392 (in isoform 2)Phosphorylation-4.5228348404
392 (in isoform 3)Phosphorylation-4.5228348404
394 (in isoform 2)Phosphorylation-4.0728348404
394 (in isoform 3)Phosphorylation-4.0728348404
395 (in isoform 2)Phosphorylation-28.3628348404
395 (in isoform 3)Phosphorylation-28.3628348404
396 (in isoform 2)Phosphorylation-31.3928348404
396 (in isoform 3)Phosphorylation-31.3928348404
398 (in isoform 2)Phosphorylation-4.6328348404
398 (in isoform 3)Phosphorylation-4.6328348404
399 (in isoform 2)Phosphorylation-57.3828348404
399 (in isoform 3)Phosphorylation-57.3828348404
401 (in isoform 2)Phosphorylation-15.9328348404
401 (in isoform 3)Phosphorylation-15.9328348404
465SulfoxidationTSIQERIMSTPGGEE
HHHHHHHHCCCCHHH		4.5821406390
467PhosphorylationIQERIMSTPGGEEAI
HHHHHHCCCCHHHHH		14.4730576142
481PhosphorylationIERLKESEKIIAELN
HHHHHHHHHHHHHHH		49.7420068231
483UbiquitinationRLKESEKIIAELNET
HHHHHHHHHHHHHHH		2.9532142685
494UbiquitinationLNETWEEKLRKTEAI
HHHHHHHHHHHHHHH		41.92-
506UbiquitinationEAIRMEREALLAEMG
HHHHHHHHHHHHHHC		30.2932015554
522PhosphorylationAIREDGGTLGVFSPK
EEEECCCEEEEECCC		26.3525159151
527PhosphorylationGGTLGVFSPKKTPHL
CCEEEEECCCCCCCC		33.1425159151
529UbiquitinationTLGVFSPKKTPHLVN
EEEEECCCCCCCCCC		68.9932142685
552UbiquitinationECLLYYIKDGITRVG
HHHHHHHHHCCCEEC		33.5132015554
572PhosphorylationRRQDIVLSGAHIKEE
HHHCEEEECCEECCE		24.04-
585PhosphorylationEEHCIFRSERSNSGE
CEEEEEEECCCCCCE		26.9824719451
600UbiquitinationVIVTLEPCERSETYV
EEEEEEECCCCCEEE		5.0429967540
634UbiquitinationGKNHVFRFNHPEQAR
CCCCEEECCCHHHHH		7.1824816145
647PhosphorylationARAEREKTPSAETPS
HHHHHHCCCCCCCCC		20.0925850435
649PhosphorylationAEREKTPSAETPSEP
HHHHCCCCCCCCCCC		43.9225850435
652PhosphorylationEKTPSAETPSEPVDW
HCCCCCCCCCCCCCC		31.6528857561
654PhosphorylationTPSAETPSEPVDWTF
CCCCCCCCCCCCCHH		63.0521712546
663 (in isoform 3)Phosphorylation-34.8825159151
665 (in isoform 3)Phosphorylation-45.7025159151
669 (in isoform 3)Phosphorylation-54.5220873877
670UbiquitinationQRELLEKQGIDMKQE
HHHHHHHCCCCHHHH		44.7027667366
707PhosphorylationLEQQRLDYESKLQAL
HHHHHCCHHHHHHHH		27.0521406692
709PhosphorylationQQRLDYESKLQALQK
HHHCCHHHHHHHHHH		32.2221406692
716UbiquitinationSKLQALQKQVETRSL
HHHHHHHHHHHHHHH		58.1032015554
722PhosphorylationQKQVETRSLAAETTE
HHHHHHHHHCCCCCC		29.7628102081
724 (in isoform 3)Phosphorylation-12.4224719451
727PhosphorylationTRSLAAETTEEEEEE
HHHHCCCCCCHHHHH		34.4828102081
728PhosphorylationRSLAAETTEEEEEEE
HHHCCCCCCHHHHHC		32.6728102081
728UbiquitinationRSLAAETTEEEEEEE
HHHCCCCCCHHHHHC		32.6729967540
733 (in isoform 3)Phosphorylation-74.18-
738UbiquitinationEEEEEEVPWTQHEFE
HHHHCCCCCCHHHHH		31.5122505724
740PhosphorylationEEEEVPWTQHEFELA
HHCCCCCCHHHHHHH		17.6128102081
741UbiquitinationEEEVPWTQHEFELAQ
HCCCCCCHHHHHHHH		30.1930230243
774 (in isoform 3)Phosphorylation-36.7727762562
784UbiquitinationNAISVELKKKVQFQF
CEEEEEEHHHCCEEE		36.7232015554
784 (in isoform 4)Ubiquitination-36.72-
825UbiquitinationRPFPRTVVAVEVQDL
CCCCCEEEEEEEEEC		4.9629967540
863 (in isoform 3)Phosphorylation-8.9528176443
868 (in isoform 3)Phosphorylation-62.1928176443
870PhosphorylationASSAQDESETTVTGS
HHCCCCCCCCCCCCC		48.8330576142
871 (in isoform 3)Phosphorylation-46.5828176443
875PhosphorylationDESETTVTGSDPFYD
CCCCCCCCCCCCCCC		28.9530576142
877PhosphorylationSETTVTGSDPFYDRF
CCCCCCCCCCCCCCC		32.5130576142
892PhosphorylationHWFKLVGSSPIFHGC
HHHHHCCCCCCCCCH		26.0121712546
893PhosphorylationWFKLVGSSPIFHGCV
HHHHCCCCCCCCCHH		18.9821712546
930UbiquitinationLADEQQDEMEDFDDE
HHHHHHHHHCCCCCC		39.8821890473
930 (in isoform 3)Ubiquitination-39.8821890473
939UbiquitinationEDFDDEAFVDDAGSD
CCCCCCHHHCCCCCC		6.1121890473
939 (in isoform 3)Ubiquitination-6.1121890473
953UbiquitinationDAGTEEGSDLFSDGH
CCCCCCCCCCCCCCC		34.1332142685
971 (in isoform 3)Phosphorylation-2.4224275569
973 (in isoform 3)Phosphorylation-4.1127251275
976 (in isoform 3)Phosphorylation-7.7322912867
999UbiquitinationRVAIVSEKGEVRGFL
EEEEECCCCCHHHHH		53.5232142685
1011PhosphorylationGFLRVAVQAIAADEE
HHHHHHHHHHHCCCC		19.8119664994
1022PhosphorylationADEEAPDYGSGIRQS
CCCCCCCCCCCCCCC		16.4828176443
1024PhosphorylationEEAPDYGSGIRQSGT
CCCCCCCCCCCCCCE		25.4728176443
1027 (in isoform 3)Phosphorylation-28.3028348404
1029PhosphorylationYGSGIRQSGTAKISF
CCCCCCCCCEEEEEE		28.4128176443
1031PhosphorylationSGIRQSGTAKISFDN
CCCCCCCEEEEEECC		29.9928176443
1035PhosphorylationQSGTAKISFDNEYFN
CCCEEEEEECCCCCC		26.3229978859
1040PhosphorylationKISFDNEYFNQSDFS
EEEECCCCCCCCCCC		17.6829978859
1043UbiquitinationFDNEYFNQSDFSSVA
ECCCCCCCCCCCHHC		34.1827667366
1043 (in isoform 2)Ubiquitination-34.1821906983
1051 (in isoform 3)Phosphorylation-2.7622496350
1053 (in isoform 3)Phosphorylation-18.6825159151
1054PhosphorylationSSVAMTRSGLSLEEL
CHHCCCCCCCCHHHE		34.6125159151
1057PhosphorylationAMTRSGLSLEELRIV
CCCCCCCCHHHEEEE		36.9419664994
1069 (in isoform 3)Phosphorylation-35.5827050516
1070PhosphorylationIVEGQGQSSEVITPP
EEECCCCCCEECCCH		34.9828450419
1071PhosphorylationVEGQGQSSEVITPPE
EECCCCCCEECCCHH		28.1728450419
1075PhosphorylationGQSSEVITPPEEISR
CCCCEECCCHHHHHC		37.6625159151
1077 (in isoform 3)Phosphorylation-43.1124719451
1081PhosphorylationITPPEEISRINDLDL
CCCHHHHHCCCCCCC		30.3228450419
1089UbiquitinationRINDLDLKSSTLLDG
CCCCCCCCCCCCCCC		41.8632015554
1089 (in isoform 1)Ubiquitination-41.8621906983
1089 (in isoform 4)Ubiquitination-41.8621906983
1092PhosphorylationDLDLKSSTLLDGKMV
CCCCCCCCCCCCEEE		38.1328555341
1099 (in isoform 3)Phosphorylation-3.4424719451
1100 (in isoform 3)Phosphorylation-3.59-
1121 (in isoform 3)Phosphorylation-3.66-
1132 (in isoform 3)Phosphorylation-50.3230266825
1141 (in isoform 3)Phosphorylation-16.8230266825
1156UbiquitinationAFSTEPLKNNGRGSP
CCCCCCCCCCCCCCC		60.11-
1162PhosphorylationLKNNGRGSPLAFYHV
CCCCCCCCCCEEEEE		18.5128060719
1211PhosphorylationLQGQELNSPPQPCRR
CCCCCCCCCCCCCHH		51.0529496963
1228UbiquitinationPPPMPLSKPVPATKL
CCCCCCCCCCCCHHH		58.69-
1237PhosphorylationVPATKLNTMSKTSLG
CCCHHHCCCCCCCCC		33.0024719451
1239PhosphorylationATKLNTMSKTSLGQS
CHHHCCCCCCCCCCC		30.6429083192
1241PhosphorylationKLNTMSKTSLGQSMS
HHCCCCCCCCCCCCC		23.1329083192
1242PhosphorylationLNTMSKTSLGQSMSK
HCCCCCCCCCCCCCH		33.9529083192
1246PhosphorylationSKTSLGQSMSKYDLL
CCCCCCCCCCHHCEE		24.1929083192
1248PhosphorylationTSLGQSMSKYDLLVW
CCCCCCCCHHCEEEE		33.0529083192
1304O-linked_GlycosylationTIIHEKGSELHWKDV
EEEECCCCCCCHHHH		48.3130379171
1370PhosphorylationSSLHNSLLLNRVTPY
CCCCCHHHHCCCCCC		3.9020068231
1383PhosphorylationPYGEKIYMTLSAYLE
CCCCCEEEEHHHHHC		3.2820068231
1384PhosphorylationYGEKIYMTLSAYLEL
CCCCEEEEHHHHHCC		10.6920068231
1385UbiquitinationGEKIYMTLSAYLELD
CCCEEEEHHHHHCCC		1.2527667366
1386PhosphorylationEKIYMTLSAYLELDH
CCEEEEHHHHHCCCC		13.0020068231
1389PhosphorylationYMTLSAYLELDHCIQ
EEEHHHHHCCCCCCC		5.4320068231
1408PhosphorylationTKDVCMVFYSRDAKI
CCCEEEEEECCCCCC		1.5019664994
1416PhosphorylationYSRDAKISPPRSLRS
ECCCCCCCCCHHHHH		28.3021712546
1420PhosphorylationAKISPPRSLRSLFGS
CCCCCCHHHHHHHCC		33.6326074081
1423PhosphorylationSPPRSLRSLFGSGYS
CCCHHHHHHHCCCCC		33.0926074081
1427PhosphorylationSLRSLFGSGYSKSPD
HHHHHHCCCCCCCCC		27.5020068231
1429PhosphorylationRSLFGSGYSKSPDSN
HHHHCCCCCCCCCCC		18.0229116813
1430PhosphorylationSLFGSGYSKSPDSNR
HHHCCCCCCCCCCCC		30.1320068231
1432O-linked_GlycosylationFGSGYSKSPDSNRVT
HCCCCCCCCCCCCCC		28.1830379171
1432PhosphorylationFGSGYSKSPDSNRVT
HCCCCCCCCCCCCCC		28.1820068231
1435PhosphorylationGYSKSPDSNRVTGIY
CCCCCCCCCCCCEEE		29.8920068231
1441PhosphorylationDSNRVTGIYELSLCK
CCCCCCEEEEEEEEE		1.4420068231
1450PhosphorylationELSLCKMSDTGSPGM
EEEEEECCCCCCCHH		19.9523403867
1452PhosphorylationSLCKMSDTGSPGMQR
EEEECCCCCCCHHHH		32.0523927012
1454PhosphorylationCKMSDTGSPGMQRRR
EECCCCCCCHHHHHH		22.0019664994
1461UbiquitinationSPGMQRRRRKILDTS
CCHHHHHHHHHHHCC		46.5729967540
1467PhosphorylationRRRKILDTSVAYVRG
HHHHHHHCCCHHHCC		22.9622210691
1468PhosphorylationRRKILDTSVAYVRGE
HHHHHHCCCHHHCCC		12.3828555341
1487PhosphorylationGWRPRGDSLILEHQW
CCCCCCCEEEEEEEH		21.8222167270
1559PhosphorylationTTFESAITPSESSGY
CEECCCCCCCCCCCC		22.0722210691
1564PhosphorylationAITPSESSGYDSGDI
CCCCCCCCCCCCCCH		37.0020068231
1567PhosphorylationPSESSGYDSGDIESL
CCCCCCCCCCCHHHH		50.0619664994
1573PhosphorylationYDSGDIESLVDREKE
CCCCCHHHHHHHHHH		33.7424275569
1592PhosphorylationCLQLLTHTFNREFSQ
HHHHHHHHHCHHHHH		19.85-
1598PhosphorylationHTFNREFSQVHGSVS
HHHCHHHHHHCCCHH		26.9227050516
1603PhosphorylationEFSQVHGSVSDCKLS
HHHHHCCCHHHCCHH		11.9926657352
1605PhosphorylationSQVHGSVSDCKLSDI
HHHCCCHHHCCHHHC		38.7024972180
1610PhosphorylationSVSDCKLSDISPIGR
CHHHCCHHHCCCCCC		20.5620068231
1612PhosphorylationSDCKLSDISPIGRDP
HHCCHHHCCCCCCCC		4.7918669648
1613PhosphorylationDCKLSDISPIGRDPS
HCCHHHCCCCCCCCC		18.5619664994
1620PhosphorylationSPIGRDPSESSFSSA
CCCCCCCCCCCCCCC		55.1721815630
1622PhosphorylationIGRDPSESSFSSATL
CCCCCCCCCCCCCEE		40.8128102081
1623PhosphorylationGRDPSESSFSSATLT
CCCCCCCCCCCCEEC		25.7027251275
1626PhosphorylationPSESSFSSATLTPSS
CCCCCCCCCEECCCC		24.2228348404
1628PhosphorylationESSFSSATLTPSSTC
CCCCCCCEECCCCCC		32.8628348404
1629PhosphorylationSSFSSATLTPSSTCP
CCCCCCEECCCCCCC		7.1118669648
1630PhosphorylationSFSSATLTPSSTCPS
CCCCCEECCCCCCCH		19.4427050516
1632PhosphorylationSSATLTPSSTCPSLV
CCCEECCCCCCCHHH		32.8028102081
1633PhosphorylationSATLTPSSTCPSLVD
CCEECCCCCCCHHHC		34.9228102081
1634PhosphorylationATLTPSSTCPSLVDS
CEECCCCCCCHHHCC		32.5428102081
1637PhosphorylationTPSSTCPSLVDSRSN
CCCCCCCHHHCCCCC		43.0828102081
1641PhosphorylationTCPSLVDSRSNSLDQ
CCCHHHCCCCCCCCC		30.0828102081
1643PhosphorylationPSLVDSRSNSLDQKT
CHHHCCCCCCCCCCC		34.4228450419
1645PhosphorylationLVDSRSNSLDQKTPE
HHCCCCCCCCCCCHH		34.2726055452
1650PhosphorylationSNSLDQKTPEANSRA
CCCCCCCCHHHHHCC		22.2625159151
1655PhosphorylationQKTPEANSRASSPCP
CCCHHHHHCCCCCCC		35.9527422710
1658PhosphorylationPEANSRASSPCPEFE
HHHHHCCCCCCCHHH		33.4323401153
1659PhosphorylationEANSRASSPCPEFEQ
HHHHCCCCCCCHHHC		29.5429255136
1661GlutathionylationNSRASSPCPEFEQFQ
HHCCCCCCCHHHCCC		5.6522555962
1675PhosphorylationQIVPAVETPYLARAG
CEECCCCCCCHHCCC		15.6118669648
1677PhosphorylationVPAVETPYLARAGKN
ECCCCCCCHHCCCCC		22.0326074081
1720AcetylationPLYSNWAKHFVVVRR
CCCCCCCCEEEEECC		29.2330589719
1764PhosphorylationDQQAMVKTPNTFAVC
HHHHHHCCCCCEEEE		15.4521815630
1772PhosphorylationPNTFAVCTKHRGVLL
CCCEEEEECCCCEEE		24.2424667141
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KIF1B_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KIF1B_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KIF1B_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EF1A1_HUMANEEF1A1physical
16169070
CR025_HUMANC18orf25physical
22863883
SC24A_HUMANSEC24Aphysical
22863883
KIF1A_HUMANKIF1Aphysical
28514442
BIN2_HUMANBIN2physical
28514442
VP33B_HUMANVPS33Bphysical
28514442
SPE39_HUMANVIPAS39physical
28514442
PLOD1_HUMANPLOD1physical
28514442
DEFM_HUMANPDFphysical
28514442
PP4R1_HUMANPPP4R1physical
28514442
CING_HUMANCGNphysical
27173435
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
118210Charcot-Marie-Tooth disease 2A1 (CMT2A1)
256700Neuroblastoma 1 (NBLST1)
171300Pheochromocytoma (PCC)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KIF1B_HUMAN

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1075 AND SER-1487, ANDMASS SPECTROMETRY.
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1057, AND MASSSPECTROMETRY.
"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1057 AND SER-1487, ANDMASS SPECTROMETRY.
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1487, AND MASSSPECTROMETRY.
"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1057 AND SER-1454, ANDMASS SPECTROMETRY.

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