FA50B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FA50B_HUMAN
• UniProt AC: Q9Y247
• Protein Name: Protein FAM50B
• Gene Name: FAM50B
• Organism: Homo sapiens (Human).
• Sequence Length: 325
• Protein Sequence: MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKEDLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEKNKHIFPASRWEAYDPEKKWDKYTIR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAQYKGTMR ------CCCCCHHHH	22.78	22814378
4	Phosphorylation	----MAQYKGTMREA ----CCCCCHHHHHH	11.22	-
5	Methylation	---MAQYKGTMREAG ---CCCCCHHHHHHH	35.51	-
7	Phosphorylation	-MAQYKGTMREAGRA -CCCCCHHHHHHHHH	14.65	24719451
50	Phosphorylation	SQVDKRFSAHYDAVE HHHCHHHHHHHHHHH	20.40	26356563
53	Phosphorylation	DKRFSAHYDAVEAEL CHHHHHHHHHHHHHH	12.81	25884760
62	Phosphorylation	AVEAELKSSTVGLVT HHHHHHHHCCEEEEE	43.81	20068231
63	Phosphorylation	VEAELKSSTVGLVTL HHHHHHHCCEEEEEH	26.06	25159151
64	Phosphorylation	EAELKSSTVGLVTLN HHHHHHCCEEEEEHH	26.19	20068231
69	Phosphorylation	SSTVGLVTLNDMKAR HCCEEEEEHHHHHHH	25.53	20068231
118	Phosphorylation	RERKRKISCLSFALD HHHHHHHHHHHHHHC	16.43	29507054
121	Phosphorylation	KRKISCLSFALDDLD HHHHHHHHHHHCCCC	16.89	29507054
144	Ubiquitination	RRAGNLGKNPDVDTS HHHHCCCCCCCCCCC	69.35	-
150	Phosphorylation	GKNPDVDTSFLPDRD CCCCCCCCCCCCCCC	22.64	25850435
151	Phosphorylation	KNPDVDTSFLPDRDR CCCCCCCCCCCCCCH	21.96	21815630
156	Methylation	DTSFLPDRDREEEEN CCCCCCCCCHHHHHH	42.84	-
291	Sumoylation	KDESHAGKVVLRSWY CCCCHHCHHHHHHHH	29.92	-
291	Sumoylation	KDESHAGKVVLRSWY CCCCHHCHHHHHHHH	29.92	-
291	Ubiquitination	KDESHAGKVVLRSWY CCCCHHCHHHHHHHH	29.92	-
295	Methylation	HAGKVVLRSWYEKNK HHCHHHHHHHHHHCC	17.34	-
302	Ubiquitination	RSWYEKNKHIFPASR HHHHHHCCCCCCCHH	49.50	-
308	Phosphorylation	NKHIFPASRWEAYDP CCCCCCCHHHCCCCC	37.86	24719451
313	Phosphorylation	PASRWEAYDPEKKWD CCHHHCCCCCCCCCC	22.10	24719451
322	Phosphorylation	PEKKWDKYTIR---- CCCCCCCCCCC----	12.62	-
323	Phosphorylation	EKKWDKYTIR----- CCCCCCCCCC-----	18.93	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FA50B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FA50B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FA50B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RT16_HUMAN	MRPS16	physical	22939629
HDAC2_HUMAN	HDAC2	physical	22939629
RM54_HUMAN	MRPL54	physical	22939629
SPEB_HUMAN	AGMAT	physical	22939629
LDOC1_HUMAN	LDOC1	physical	19060904
CARD9_HUMAN	CARD9	physical	25416956
CCD57_HUMAN	CCDC57	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.