dbPTM

ZN821_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ZN821_HUMAN
UniProt AC	O75541
Protein Name	Zinc finger protein 821
Gene Name	ZNF821
Organism	Homo sapiens (Human).
Sequence Length	412
Subcellular Localization	Nucleus .
Protein Description	May be involved in transcriptional regulation..
Protein Sequence	MSRRKQTNPNKVHWDQVFAGLEEQARQAMMKTDFPGDLGSQRQAIQQLRDQDSSSSDSEGDEEETTQDEVSSHTSEEDGGVVKVEKELENTEQPVGGNEVVEHEVTGNLNSDPLLELCQCPLCQLDCGSREQLIAHVYQHTAAVVSAKSYMCPVCGRALSSPGSLGRHLLIHSEDQRSNCAVCGARFTSHATFNSEKLPEVLNMESLPTVHNEGPSSAEGKDIAFSPPVYPAGILLVCNNCAAYRKLLEAQTPSVRKWALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQARLIREREAKRLKRRLEKMDMMLRAQFGQDPSAMAALAAEMNFFQLPVSGVELDSQLLGKMAFEEQNSSSLH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
150	Phosphorylation	AVVSAKSYMCPVCGR HHHCCCCCCCCCCCC	11.30	22461510
160	Phosphorylation	PVCGRALSSPGSLGR CCCCCCCCCCCCHHC	33.24	24719451
164	Phosphorylation	RALSSPGSLGRHLLI CCCCCCCCHHCCEEE	30.91	22461510
188	Phosphorylation	AVCGARFTSHATFNS EECCCEEEECCCCCC	17.66	29052541
189	Phosphorylation	VCGARFTSHATFNSE ECCCEEEECCCCCCC	14.38	29052541
192	Phosphorylation	ARFTSHATFNSEKLP CEEEECCCCCCCCCC	20.23	29052541
195	Phosphorylation	TSHATFNSEKLPEVL EECCCCCCCCCCHHH	31.73	29052541
279	Phosphorylation	QRLERERTAKKSRRD HHHHHHHHHHHHHCC	37.77	27251275
330	Methylation	DREAMRLKRANETPE HHHHHHHHHCCCCHH	38.82	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ZN821_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ZN821_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ZN821_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
LURA1_HUMAN	LURAP1	physical	16189514

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ZN821_HUMAN

Related Literatures of Post-Translational Modification