ZN564_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN564_HUMAN
• UniProt AC: Q8TBZ8
• Protein Name: Zinc finger protein 564
• Gene Name: ZNF564
• Organism: Homo sapiens (Human).
• Sequence Length: 553
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MDSVASEDVAVNFTLEEWALLDPSQKKLYRDVMRETFRNLACVGKKWEDQSIEDWYKNQGRILRNHMEEGLSESKEYDQCGEAFSQILNLNLNKKIPTIVRPCECSLCGKVFMHHSSLSRHIRSHLGHKPYDYQEYGEKPYKCKQCGKAFSSCQSFRRHERTHTGEKPYACPECGKAFISLPSVRRHMIKHTGDGPYKCQECGKAFDRPSLFQIHERTHTGEKPYECQECAKAFISLPSFQRHMIRHTGDGPYKCQECGKAFDRPSLFRIHERTHTGEKPHECKQCGKAFISFTNFQSHMIRHTGDGPYKCKVCGRAFIFPSYVRKHERTHTGEKPYECNKCGKTFSSSSNVRTHERTHTGEKPYECKECGKAFISLPSVRRHMIKHTGDGPYKCQVCGRAFDCPSSFQIHERTHTGEKPYECQVCGKAFISLKRIRKHMILHTGDGPYKCQVCGKAFDCPSSVRTHERTHTGEKPYECKECGKAFNYASSIRIHERTHTGEKPYECKQCGKTFSYSSSFQRHERAHNGDKPYVKNVGKLSFITQPSNTCENE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
46	Sumoylation	NLACVGKKWEDQSIE HHHHCCCCCCCCCHH	50.30	-
46	Sumoylation	NLACVGKKWEDQSIE HHHHCCCCCCCCCHH	50.30	-
162	Phosphorylation	SFRRHERTHTGEKPY HHHHHCCCCCCCCCC	22.32	-
164	Phosphorylation	RRHERTHTGEKPYAC HHHCCCCCCCCCCCC	46.56	-
180	Phosphorylation	ECGKAFISLPSVRRH CCCCEEECCHHHHHH	27.98	27080861
183	Phosphorylation	KAFISLPSVRRHMIK CEEECCHHHHHHCCH	33.28	28450419
192	Phosphorylation	RRHMIKHTGDGPYKC HHHCCHHCCCCCCCC	31.78	28348404
218	Phosphorylation	LFQIHERTHTGEKPY CEEEECCCCCCCCCC	22.32	-
220	Phosphorylation	QIHERTHTGEKPYEC EEECCCCCCCCCCCH	46.56	-
248	Phosphorylation	QRHMIRHTGDGPYKC HHHHCHHCCCCCCCC	27.41	28348404
274	Phosphorylation	LFRIHERTHTGEKPH HEEEECCCCCCCCCC	22.32	-
276	Phosphorylation	RIHERTHTGEKPHEC EEECCCCCCCCCCCC	46.56	-
323	Phosphorylation	RAFIFPSYVRKHERT CEEECHHHHHHCCCC	12.43	-
330	Phosphorylation	YVRKHERTHTGEKPY HHHHCCCCCCCCCCE	22.32	-
332	Phosphorylation	RKHERTHTGEKPYEC HHCCCCCCCCCCEEC	46.56	-
349	Phosphorylation	CGKTFSSSSNVRTHE CCCCCCCCCCCEEEC	25.41	30576142
350	Phosphorylation	GKTFSSSSNVRTHER CCCCCCCCCCEEECC	41.09	30576142
354	Phosphorylation	SSSSNVRTHERTHTG CCCCCCEEECCCCCC	24.65	30576142
358	Phosphorylation	NVRTHERTHTGEKPY CCEEECCCCCCCCCE	22.32	29396449
360	Phosphorylation	RTHERTHTGEKPYEC EEECCCCCCCCCEEC	46.56	29496963
363	Ubiquitination	ERTHTGEKPYECKEC CCCCCCCCCEECCCC	55.00	-
368	Ubiquitination	GEKPYECKECGKAFI CCCCEECCCCCCEEE	44.06	-
368	Sumoylation	GEKPYECKECGKAFI CCCCEECCCCCCEEE	44.06	-
368	Sumoylation	GEKPYECKECGKAFI CCCCEECCCCCCEEE	44.06	-
376	Phosphorylation	ECGKAFISLPSVRRH CCCCEEECCHHHHHH	27.98	27080861
379	Phosphorylation	KAFISLPSVRRHMIK CEEECCHHHHHHHHH	33.28	28450419
388	Phosphorylation	RRHMIKHTGDGPYKC HHHHHHHCCCCCCEE	31.78	-
414	Phosphorylation	SFQIHERTHTGEKPY CEEEEECCCCCCCCE	22.32	-
416	Phosphorylation	QIHERTHTGEKPYEC EEEECCCCCCCCEEC	46.56	-
438	Sumoylation	ISLKRIRKHMILHTG EEHHHHHHCEEEECC	34.84	-
438	Sumoylation	ISLKRIRKHMILHTG EEHHHHHHCEEEECC	34.84	28112733
444	Phosphorylation	RKHMILHTGDGPYKC HHCEEEECCCCCEEE	33.26	21857030
470	Phosphorylation	SVRTHERTHTGEKPY CCCCCCCCCCCCCCE	22.32	29396449
472	Phosphorylation	RTHERTHTGEKPYEC CCCCCCCCCCCCEEC	46.56	29496963
475	Ubiquitination	ERTHTGEKPYECKEC CCCCCCCCCEECCHH	55.00	-
480	Ubiquitination	GEKPYECKECGKAFN CCCCEECCHHHCCCC	44.06	-
480	Sumoylation	GEKPYECKECGKAFN CCCCEECCHHHCCCC	44.06	-
480	Sumoylation	GEKPYECKECGKAFN CCCCEECCHHHCCCC	44.06	-
498	Phosphorylation	SIRIHERTHTGEKPY CEEEEECCCCCCCCE	22.32	29396449
500	Phosphorylation	RIHERTHTGEKPYEC EEEECCCCCCCCEEC	46.56	29496963
503	Ubiquitination	ERTHTGEKPYECKQC ECCCCCCCCEECCCC	55.00	-
508	Sumoylation	GEKPYECKQCGKTFS CCCCEECCCCCCEEE	36.36	-
508	Sumoylation	GEKPYECKQCGKTFS CCCCEECCCCCCEEE	36.36	-
539	Sumoylation	PYVKNVGKLSFITQP CCCCEECEEEEEECC	36.35	-
539	Sumoylation	PYVKNVGKLSFITQP CCCCEECEEEEEECC	36.35	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN564_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN564_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN564_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SPERT_HUMAN	SPERT	physical	25416956
KR107_HUMAN	KRTAP10-7	physical	25416956
KR109_HUMAN	KRTAP10-9	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.