FA13C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FA13C_HUMAN
• UniProt AC: Q8NE31
• Protein Name: Protein FAM13C
• Gene Name: FAM13C
• Organism: Homo sapiens (Human).
• Sequence Length: 585
• Protein Sequence: MFSCFCFSLQDNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRPSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
94	Phosphorylation	FKSRKPKSIFKAESG CCCCCCCCEEECCCC	41.61	24719451
126	Phosphorylation	ECQVRAGTPAHESPQ EEEEECCCCCCCCCC	19.13	30266825
131	Phosphorylation	AGTPAHESPQNNAFK CCCCCCCCCCCCCCC	23.17	30266825
153	Phosphorylation	QPRIDQRTAISPKDA CCCCCCCCCCCHHHH	23.78	24719451
156	Phosphorylation	IDQRTAISPKDAFET CCCCCCCCHHHHHHH	24.35	30257219
158	Acetylation	QRTAISPKDAFETRQ CCCCCCHHHHHHHCC	55.70	11925369
185	Phosphorylation	VKDPAPASTQSVLAD CCCCCCCCCCCHHCC	26.39	27732954
186	Phosphorylation	KDPAPASTQSVLADG CCCCCCCCCCHHCCC	27.28	27732954
188	Phosphorylation	PAPASTQSVLADGTD CCCCCCCCHHCCCCC	21.13	27732954
194	Phosphorylation	QSVLADGTDSADPSP CCHHCCCCCCCCCCC	27.59	27732954
196	Phosphorylation	VLADGTDSADPSPVH HHCCCCCCCCCCCCC	34.12	27732954
200	Phosphorylation	GTDSADPSPVHKDGQ CCCCCCCCCCCCCCC	39.85	27732954
212	Phosphorylation	DGQNEADSAPEDLHS CCCCCCCCCCHHHHH	53.42	27732954
219	Phosphorylation	SAPEDLHSVGTSRLL CCCHHHHHCCCCEEE	29.55	27732954
222	Phosphorylation	EDLHSVGTSRLLYHI HHHHHCCCCEEEEEE	14.44	27732954
223	Phosphorylation	DLHSVGTSRLLYHIT HHHHCCCCEEEEEEC	18.27	27732954
238	Phosphorylation	DGDNPLLSPRCSIFS CCCCCCCCCCCEECC	20.27	24719451
385	Phosphorylation	AAGPEPSSSGEETPD CCCCCCCCCCCCCCH	53.75	-
386	Phosphorylation	AGPEPSSSGEETPDA CCCCCCCCCCCCCHH	55.34	-
577	Phosphorylation	RLLEVLISKQDVAKT HHHHHHHHHHHHHHC	21.80	22964224

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FA13C_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FA13C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FA13C_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FA13C_HUMAN	FAM13C	physical	25416956
CC172_HUMAN	CCDC172	physical	25416956
TBA3C_HUMAN	TUBA3C	physical	26186194
SAHH3_HUMAN	AHCYL2	physical	26186194
SAHH2_HUMAN	AHCYL1	physical	26186194
PZRN3_HUMAN	PDZRN3	physical	26186194
PZRN3_HUMAN	PDZRN3	physical	28514442
SAHH3_HUMAN	AHCYL2	physical	28514442
TBA3C_HUMAN	TUBA3C	physical	28514442
SAHH2_HUMAN	AHCYL1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.