CC172_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC172_HUMAN
• UniProt AC: P0C7W6
• Protein Name: Coiled-coil domain-containing protein 172
• Gene Name: CCDC172
• Organism: Homo sapiens (Human).
• Sequence Length: 258
• Subcellular Localization: Cytoplasm . Cell projection, cilium . In spermatozoa, localized in the middle piece, predominantly concentrated at the mitochondrial sheath of the flagella and to a lesser extent with outer dense fibers (ODF) (By similarity). Colocalized with TEKT2 a
• Protein Sequence: MSLESLFQHIIFTEHQAEESRRLMREVRSEITRCREKIKKATEELNEEKIKLESKVQQFFEKSFFLQLLKAHENALEKQYSEITNHRNMLLQTFEAIKKQMIEEEDKFIKEITDFNNDYEITKKRELLMKENVKIEISDLENQANMLKSEMKSMEHDSSQLNELQKQKSELIQELFTLQRKLKVFEDEENESICTTKYLEAEKIKISEKPQNDTECLRLKKELELYKEDDMESVYEALQTEIEFLELTLAQKDLQESK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
42	Phosphorylation	REKIKKATEELNEEK HHHHHHHHHHHHHHH	38.58	19664994
81	Phosphorylation	NALEKQYSEITNHRN HHHHHHHHHHHHHHH	21.74	-
93	Phosphorylation	HRNMLLQTFEAIKKQ HHHHHHHHHHHHHHH	24.34	-
149	Phosphorylation	NQANMLKSEMKSMEH HHHHHHHHHHHHCCC	38.67	25954137

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC172_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC172_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC172_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KDM1A_HUMAN	KDM1A	physical	23455924
MESH1_HUMAN	HDDC3	physical	25416956
PKHF2_HUMAN	PLEKHF2	physical	21516116
CC122_HUMAN	CCDC122	physical	28514442
NINL_HUMAN	NINL	physical	28514442
MIPO1_HUMAN	MIPOL1	physical	28514442
PCM1_HUMAN	PCM1	physical	28514442
BBS4_HUMAN	BBS4	physical	28514442
EPS15_HUMAN	EPS15	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.