PCM1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PCM1_HUMAN
• UniProt AC: Q15154
• Protein Name: Pericentriolar material 1 protein
• Gene Name: PCM1
• Organism: Homo sapiens (Human).
• Sequence Length: 2024
• Subcellular Localization: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasmic granule . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Cytoplasm, cytoskeleton, cilium basal body . Not
• Protein Description: Required for centrosome assembly and function. Essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. Required to anchor microtubules to the centrosome. Involved in the biogenesis of cilia..
• Protein Sequence: MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMSQMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALSNDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPMEEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPAVPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSASPQRSVDQRSTSAPSASVGLAPVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHENSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLDCRYNREGEQEIHVAQGEDDEEEEEEAEEEGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANKTQKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSVFEPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDEEGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSELSYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQMLNELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQNSSGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLESFSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRKNHEQLEKIIKCNRSTEISSETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEKGENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTEAESNSNMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEHMDEVCSSQLLTSVRRMVLTLTQQNDESKEFVKFFHKQLGSILQDSLAKFAGRKLKDCGEDLLVEISEVLFNELAFFKLMQDLDNNSITVKQRCKRKIEATGVIQSCAKEAKRILEDHGSPAGEIDDEDKDKDETETVKQTQTSEVYDGPKNVRSDISDQEEDEESEGCPVSINLSKAETQALTNYGSGEDENEDEEMEEFEEGPVDVQTSLQANTEATEENEHDEQVLQRDFKKTAESKNVPLEREATSKNDQNNCPVKPCYLNILEDEQPLNSAAHKESPPTVDSTQQPNPLPLRLPEMEPLVPRVKEVKSAQETPESSLAGSPDTESPVLVNDYEAESGNISQKSDEEDFVKVEDLPLKLTIYSEADLRKKMVEEEQKNHLSGEICEMQTEELAGNSETLKEPETVGAQSI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MATGGGPFE ------CCCCCCCCC	26.68	22223895
3	Phosphorylation	-----MATGGGPFED -----CCCCCCCCCC	48.49	25850435
25	Ubiquitination	PNWSNENVDDRLNNM CCCCCCCHHHHHHCC	7.07	21890473
37	Ubiquitination	NNMDWGAQQKKANRS HCCCHHHHHHHHHCC	52.25	-
39	Ubiquitination	MDWGAQQKKANRSSE CCHHHHHHHHHCCCH	41.60	-
39 (in isoform 1)	Ubiquitination	-	41.60	21890473
39 (in isoform 2)	Ubiquitination	-	41.60	21890473
39 (in isoform 3)	Ubiquitination	-	41.60	21890473
51	Ubiquitination	SSEKNKKKFGVESDK CCHHHHHHHCCCCCC	49.30	21890473
56	Phosphorylation	KKKFGVESDKRVTND HHHHCCCCCCCCCCC	46.13	21815630
58	Acetylation	KFGVESDKRVTNDIS HHCCCCCCCCCCCCC	59.03	25953088
58	Ubiquitination	KFGVESDKRVTNDIS HHCCCCCCCCCCCCC	59.03	-
61	Phosphorylation	VESDKRVTNDISPES CCCCCCCCCCCCCCC	31.07	23927012
61 (in isoform 3)	Phosphorylation	-	31.07	21406692
65	Phosphorylation	KRVTNDISPESSPGV CCCCCCCCCCCCCCC	26.02	19664994
65 (in isoform 3)	Phosphorylation	-	26.02	21406692
68	Phosphorylation	TNDISPESSPGVGRR CCCCCCCCCCCCCCC	45.26	29255136
68 (in isoform 3)	Phosphorylation	-	45.26	21406692
69	Phosphorylation	NDISPESSPGVGRRR CCCCCCCCCCCCCCC	24.82	29255136
69 (in isoform 3)	Phosphorylation	-	24.82	21406692
77	Phosphorylation	PGVGRRRTKTPHTFP CCCCCCCCCCCCCCC	37.14	29496963
78	Ubiquitination	GVGRRRTKTPHTFPH CCCCCCCCCCCCCCC	59.24	-
79	Phosphorylation	VGRRRTKTPHTFPHS CCCCCCCCCCCCCCH	21.49	25159151
82	Phosphorylation	RRTKTPHTFPHSRYM CCCCCCCCCCCHHHH	39.81	25159151
86	Phosphorylation	TPHTFPHSRYMSQMS CCCCCCCHHHHHHCC	25.91	22199227
88	Phosphorylation	HTFPHSRYMSQMSVP CCCCCHHHHHHCCCC	12.25	23927012
90	Phosphorylation	FPHSRYMSQMSVPEQ CCCHHHHHHCCCCCH	17.50	30266825
93	Phosphorylation	SRYMSQMSVPEQAEL HHHHHHCCCCCHHHH	27.21	29255136
93 (in isoform 3)	Phosphorylation	-	27.21	21406692
102	Ubiquitination	PEQAELEKLKQRINF CCHHHHHHHHHHCCC	73.87	21890473
102 (in isoform 1)	Ubiquitination	-	73.87	21890473
102 (in isoform 2)	Ubiquitination	-	73.87	21890473
102 (in isoform 3)	Ubiquitination	-	73.87	21890473
104	Ubiquitination	QAELEKLKQRINFSD HHHHHHHHHHCCCHH	48.90	21890473
110	Phosphorylation	LKQRINFSDLDQRSI HHHHCCCHHCCCCCC	32.54	19664994
116	Phosphorylation	FSDLDQRSIGSDSQG CHHCCCCCCCCCHHH	26.18	25159151
119	Phosphorylation	LDQRSIGSDSQGRAT CCCCCCCCCHHHHHH	32.21	25159151
121	Phosphorylation	QRSIGSDSQGRATAA CCCCCCCHHHHHHHH	35.91	25159151
126	Phosphorylation	SDSQGRATAANNKRQ CCHHHHHHHHHCCHH	25.58	23090842
135	Phosphorylation	ANNKRQLSENRKPFN HHCCHHCCCCCCCCC	25.20	28857561
139	Ubiquitination	RQLSENRKPFNFLPM HHCCCCCCCCCCCCC	66.59	-
139	Ubiquitination	RQLSENRKPFNFLPM HHCCCCCCCCCCCCC	66.59	21890473
139 (in isoform 3)	Ubiquitination	-	66.59	21890473
150	Phosphorylation	FLPMQINTNKSKDAS CCCCEECCCCCCCCC	45.73	26074081
152	Ubiquitination	PMQINTNKSKDASTN CCEECCCCCCCCCCC	57.77	21890473
152 (in isoform 3)	Ubiquitination	-	57.77	21890473
153	Phosphorylation	MQINTNKSKDASTNP CEECCCCCCCCCCCC	37.53	23927012
154	Ubiquitination	QINTNKSKDASTNPP EECCCCCCCCCCCCC	59.95	-
157	Phosphorylation	TNKSKDASTNPPNRE CCCCCCCCCCCCCHH	39.28	26074081
157	Phosphorylation	TNKSKDASTNPPNRE CCCCCCCCCCCCCHH	39.28	26074081
157	Phosphorylation	TNKSKDASTNPPNRE CCCCCCCCCCCCCHH	39.28	30266825
158	Phosphorylation	NKSKDASTNPPNRET CCCCCCCCCCCCHHH	47.15	18767875
158	Phosphorylation	NKSKDASTNPPNRET CCCCCCCCCCCCHHH	47.15	18767875
158	Phosphorylation	NKSKDASTNPPNRET CCCCCCCCCCCCHHH	47.15	23401153
159	Phosphorylation	KSKDASTNPPNRETI CCCCCCCCCCCHHHC	35.55	29255136
165	Phosphorylation	TNPPNRETIGSAQCK CCCCCHHHCCHHHHH	27.66	26074081
165	Phosphorylation	TNPPNRETIGSAQCK CCCCCHHHCCHHHHH	27.66	26074081
165	Phosphorylation	TNPPNRETIGSAQCK CCCCCHHHCCHHHHH	27.66	23927012
168	Phosphorylation	PNRETIGSAQCKELF CCHHHCCHHHHHHHH	16.00	26074081
168	Phosphorylation	PNRETIGSAQCKELF CCHHHCCHHHHHHHH	16.00	26074081
168	Phosphorylation	PNRETIGSAQCKELF CCHHHCCHHHHHHHH	16.00	23927012
172	Ubiquitination	TIGSAQCKELFASAL HCCHHHHHHHHHHHH	45.42	-
172 (in isoform 1)	Ubiquitination	-	45.42	21890473
172 (in isoform 2)	Ubiquitination	-	45.42	21890473
172 (in isoform 3)	Ubiquitination	-	45.42	21890473
177	Phosphorylation	QCKELFASALSNDLL HHHHHHHHHHCCHHH	23.55	26074081
180	Phosphorylation	ELFASALSNDLLQNC HHHHHHHCCHHHHHC	28.19	27251275
190	Phosphorylation	LLQNCQVSEEDGRGE HHHHCCCCCCCCCCC	14.91	29507054
202	Phosphorylation	RGEPAMESSQIVSRL CCCCCHHHHHHHHHH	17.92	26471730
203	Phosphorylation	GEPAMESSQIVSRLV CCCCHHHHHHHHHHH	15.60	26471730
215	Phosphorylation	RLVQIRDYITKASSM HHHHHHHHHHHHHHH	10.71	-
218	Ubiquitination	QIRDYITKASSMRED HHHHHHHHHHHHHHH	36.39	21890473
218 (in isoform 1)	Ubiquitination	-	36.39	21890473
218 (in isoform 2)	Ubiquitination	-	36.39	21890473
218 (in isoform 3)	Ubiquitination	-	36.39	21890473
229	Ubiquitination	MREDLVEKNERSANV HHHHHHHHCHHHHHH	57.54	-
229 (in isoform 1)	Ubiquitination	-	57.54	21890473
229 (in isoform 2)	Ubiquitination	-	57.54	21890473
229 (in isoform 3)	Ubiquitination	-	57.54	21890473
230	Ubiquitination	REDLVEKNERSANVE HHHHHHHCHHHHHHH	36.09	-
247	Ubiquitination	THLIDHLKEQEKSYM HHHHHHHHHHHHHHH	54.66	-
251	Ubiquitination	DHLKEQEKSYMKFLK HHHHHHHHHHHHHHH	46.73	-
255	Ubiquitination	EQEKSYMKFLKKILA HHHHHHHHHHHHHHC	39.03	21890473
255 (in isoform 3)	Ubiquitination	-	39.03	21890473
258	Ubiquitination	KSYMKFLKKILARDP HHHHHHHHHHHCCCC	40.68	-
259	Ubiquitination	SYMKFLKKILARDPQ HHHHHHHHHHCCCCC	45.13	-
277	Ubiquitination	MEEIENLKKQHDLLK HHHHHHHHHHHHHHH	63.07	-
277 (in isoform 1)	Ubiquitination	-	63.07	21890473
277 (in isoform 2)	Ubiquitination	-	63.07	21890473
278	Ubiquitination	EEIENLKKQHDLLKR HHHHHHHHHHHHHHH	56.91	-
284	Ubiquitination	KKQHDLLKRMLQQQE HHHHHHHHHHHHHHH	42.96	-
286	Sulfoxidation	QHDLLKRMLQQQEQL HHHHHHHHHHHHHHH	3.66	21406390
301	Ubiquitination	RALQGRQAALLALQH HHHHHHHHHHHHHHH	9.94	-
308	Ubiquitination	AALLALQHKAEQAIA HHHHHHHHHHHHHHH	31.95	-
316 (in isoform 3)	Ubiquitination	-	3.36	21890473
320	Phosphorylation	AIAVMDDSVVAETAG HHHHCCHHHHHHCCC	17.77	-
330	Phosphorylation	AETAGSLSGVSITSE HHCCCCCCCCCHHHH	38.55	24275569
336	Phosphorylation	LSGVSITSELNEELN CCCCCHHHHHHHHHH	38.12	24275569
338	Ubiquitination	GVSITSELNEELNDL CCCHHHHHHHHHHHH	11.08	-
342	Ubiquitination	TSELNEELNDLIQRF HHHHHHHHHHHHHHH	5.01	-
346	Ubiquitination	NEELNDLIQRFHNQL HHHHHHHHHHHHHHH	2.85	-
356	Phosphorylation	FHNQLRDSQPPAVPD HHHHHHHCCCCCCCC	37.85	17525332
358	Ubiquitination	NQLRDSQPPAVPDNR HHHHHCCCCCCCCCH	23.83	-
370	Phosphorylation	DNRRQAESLSLTREV CCHHHHHHHHHHHHH	26.69	30266825
372	Phosphorylation	RRQAESLSLTREVSQ HHHHHHHHHHHHHHH	36.65	30266825
374	Phosphorylation	QAESLSLTREVSQSR HHHHHHHHHHHHHCC	22.77	30266825
378	Phosphorylation	LSLTREVSQSRKPSA HHHHHHHHHCCCCCH	20.06	26074081
380	Phosphorylation	LTREVSQSRKPSASE HHHHHHHCCCCCHHH	34.46	26074081
382	Ubiquitination	REVSQSRKPSASERL HHHHHCCCCCHHHCC	48.88	-
384	Phosphorylation	VSQSRKPSASERLPD HHHCCCCCHHHCCCH	47.68	23927012
386	Phosphorylation	QSRKPSASERLPDEK HCCCCCHHHCCCHHH	27.82	23927012
393	Ubiquitination	SERLPDEKVELFSKM HHCCCHHHHHHHHHH	48.68	21890473
393 (in isoform 1)	Ubiquitination	-	48.68	21890473
393 (in isoform 2)	Ubiquitination	-	48.68	21890473
398	Phosphorylation	DEKVELFSKMRVLQE HHHHHHHHHHHHHHH	37.86	24719451
399	Acetylation	EKVELFSKMRVLQEK HHHHHHHHHHHHHHH	24.32	19608861
399	Ubiquitination	EKVELFSKMRVLQEK HHHHHHHHHHHHHHH	24.32	21890473
399 (in isoform 1)	Ubiquitination	-	24.32	21890473
399 (in isoform 2)	Ubiquitination	-	24.32	21890473
400	Ubiquitination	KVELFSKMRVLQEKK HHHHHHHHHHHHHHH	3.29	-
406	Ubiquitination	KMRVLQEKKQKMDKL HHHHHHHHHHHHHHH	47.76	-
407	Acetylation	MRVLQEKKQKMDKLL HHHHHHHHHHHHHHH	55.16	22368985
409	Ubiquitination	VLQEKKQKMDKLLGE HHHHHHHHHHHHHHH	58.93	-
409	Acetylation	VLQEKKQKMDKLLGE HHHHHHHHHHHHHHH	58.93	22368995
409	Ubiquitination	VLQEKKQKMDKLLGE HHHHHHHHHHHHHHH	58.93	21890473
412	Ubiquitination	EKKQKMDKLLGELHT HHHHHHHHHHHHHHH	41.96	-
412	Acetylation	EKKQKMDKLLGELHT HHHHHHHHHHHHHHH	41.96	25953088
412	Ubiquitination	EKKQKMDKLLGELHT HHHHHHHHHHHHHHH	41.96	21890473
412 (in isoform 1)	Ubiquitination	-	41.96	21890473
412 (in isoform 2)	Ubiquitination	-	41.96	21890473
419	Phosphorylation	KLLGELHTLRDQHLN HHHHHHHHHHHHHCC	35.79	27174698
428	Phosphorylation	RDQHLNNSSASPQRS HHHHCCCCCCCCCCC	30.44	30266825
429	Phosphorylation	DQHLNNSSASPQRSV HHHCCCCCCCCCCCC	36.64	30266825
430	Phosphorylation	QHLNNSSASPQRSVD HHCCCCCCCCCCCCC	45.95	30266825
431	Phosphorylation	HLNNSSASPQRSVDQ HCCCCCCCCCCCCCC	27.31	29255136
432 (in isoform 3)	Ubiquitination	-	35.24	21890473
435	Phosphorylation	SSASPQRSVDQRSTS CCCCCCCCCCCCCCC	25.46	30576142
438 (in isoform 3)	Ubiquitination	-	38.78	21890473
440	Phosphorylation	QRSVDQRSTSAPSAS CCCCCCCCCCCCCCC	22.53	26074081
441	Phosphorylation	RSVDQRSTSAPSASV CCCCCCCCCCCCCCC	30.97	26074081
442	Phosphorylation	SVDQRSTSAPSASVG CCCCCCCCCCCCCCC	39.15	26074081
445	Phosphorylation	QRSTSAPSASVGLAP CCCCCCCCCCCCEEC	32.65	26074081
447	Phosphorylation	STSAPSASVGLAPVV CCCCCCCCCCEECEE	22.51	26074081
448 (in isoform 3)	Ubiquitination	-	7.92	21890473
451 (in isoform 3)	Ubiquitination	-	6.74	21890473
458	Phosphorylation	APVVNGESNSLTSSV ECEECCCCCCCCCCC	32.87	28348404
460	Phosphorylation	VVNGESNSLTSSVPY EECCCCCCCCCCCCC	42.16	28348404
462	Phosphorylation	NGESNSLTSSVPYPT CCCCCCCCCCCCCCC	20.83	26074081
463	Phosphorylation	GESNSLTSSVPYPTA CCCCCCCCCCCCCCH	34.33	26074081
464	Phosphorylation	ESNSLTSSVPYPTAS CCCCCCCCCCCCCHH	23.13	26074081
467	Phosphorylation	SLTSSVPYPTASLVS CCCCCCCCCCHHHHC	15.85	26074081
468 (in isoform 3)	Phosphorylation	-	18.54	21406692
469	Phosphorylation	TSSVPYPTASLVSQN CCCCCCCCHHHHCCC	24.04	26074081
469 (in isoform 3)	Phosphorylation	-	24.04	21406692
470 (in isoform 3)	Phosphorylation	-	9.07	21406692
471	Phosphorylation	SVPYPTASLVSQNES CCCCCCHHHHCCCCC	31.61	26074081
474	Phosphorylation	YPTASLVSQNESENE CCCHHHHCCCCCCCC	32.36	26074081
478	Phosphorylation	SLVSQNESENEGHLN HHHCCCCCCCCCCCC	53.95	26074081
487	Phosphorylation	NEGHLNPSEKLQKLN CCCCCCHHHHHHHHH	46.41	26074081
489	Ubiquitination	GHLNPSEKLQKLNEV CCCCHHHHHHHHHHH	61.63	-
489	Ubiquitination	GHLNPSEKLQKLNEV CCCCHHHHHHHHHHH	61.63	-
489 (in isoform 2)	Ubiquitination	-	61.63	-
492	Ubiquitination	NPSEKLQKLNEVRKR CHHHHHHHHHHHHHH	64.81	-
492	Acetylation	NPSEKLQKLNEVRKR CHHHHHHHHHHHHHH	64.81	25953088
492	Ubiquitination	NPSEKLQKLNEVRKR CHHHHHHHHHHHHHH	64.81	21890473
492 (in isoform 1)	Ubiquitination	-	64.81	21890473
492 (in isoform 2)	Ubiquitination	-	64.81	21890473
509	Phosphorylation	ELRELVHYYEQTSDM HHHHHHHHHHHHHHH	10.96	23917254
510	Phosphorylation	LRELVHYYEQTSDMM HHHHHHHHHHHHHHH	6.15	29449344
513	Phosphorylation	LVHYYEQTSDMMTDA HHHHHHHHHHHHHHH	18.11	29449344
514	Phosphorylation	VHYYEQTSDMMTDAV HHHHHHHHHHHHHHH	24.17	29449344
518	Phosphorylation	EQTSDMMTDAVNENR HHHHHHHHHHHHHCC	17.73	27690223
530	Phosphorylation	ENRKDEETEESEYDS HCCCCCCCHHCCCCC	42.90	23927012
531 (in isoform 3)	Ubiquitination	-	63.91	21890473
533	Phosphorylation	KDEETEESEYDSEHE CCCCCHHCCCCCCCC	34.91	23927012
535	Phosphorylation	EETEESEYDSEHENS CCCHHCCCCCCCCCC	33.76	23927012
537	Phosphorylation	TEESEYDSEHENSEP CHHCCCCCCCCCCCC	39.69	23927012
542	Phosphorylation	YDSEHENSEPVTNIR CCCCCCCCCCCCCCC	40.05	23927012
546	Phosphorylation	HENSEPVTNIRNPQV CCCCCCCCCCCCHHH	35.33	23927012
549	Ubiquitination	SEPVTNIRNPQVAST CCCCCCCCCHHHHHC	51.34	-
555	Phosphorylation	IRNPQVASTWNEVNS CCCHHHHHCHHHCCC	34.79	23663014
556	Phosphorylation	RNPQVASTWNEVNSH CCHHHHHCHHHCCCC	23.67	23663014
562	Phosphorylation	STWNEVNSHSNAQCV HCHHHCCCCCCCCCC	33.21	23663014
564	Phosphorylation	WNEVNSHSNAQCVSN HHHCCCCCCCCCCCC	33.41	23663014
569	Ubiquitination	SHSNAQCVSNNRDGR CCCCCCCCCCCCCCC	4.57	-
570	Phosphorylation	HSNAQCVSNNRDGRT CCCCCCCCCCCCCCE	35.69	23663014
577	Phosphorylation	SNNRDGRTVNSNCEI CCCCCCCEECCCCEE	29.57	27251275
580	Phosphorylation	RDGRTVNSNCEINNR CCCCEECCCCEECCC	38.22	30576142
588	Phosphorylation	NCEINNRSAANIRAL CCEECCCCHHCHHHC	33.58	30576142
600	Phosphorylation	RALNMPPSLDCRYNR HHCCCCCCCCCCCCC	30.85	23917254
634	Phosphorylation	EAEEEGVSGASLSSH HHHHHCCCCHHHHHH	39.23	26471730
637	Phosphorylation	EEGVSGASLSSHRSS HHCCCCHHHHHHHHC	32.10	24275569
639	Phosphorylation	GVSGASLSSHRSSLV CCCCHHHHHHHHCCC	22.92	26471730
640	Phosphorylation	VSGASLSSHRSSLVD CCCHHHHHHHHCCCC	28.36	26471730
643	Phosphorylation	ASLSSHRSSLVDEHP HHHHHHHHCCCCCCC	23.70	23401153
644	Phosphorylation	SLSSHRSSLVDEHPE HHHHHHHCCCCCCCC	32.16	25849741
658	Ubiquitination	EDAEFEQKINRLMAA CHHHHHHHHHHHHHH	34.45	21890473
658	Ubiquitination	EDAEFEQKINRLMAA CHHHHHHHHHHHHHH	34.45	-
658	Ubiquitination	EDAEFEQKINRLMAA CHHHHHHHHHHHHHH	34.45	21890473
658 (in isoform 1)	Ubiquitination	-	34.45	21890473
658 (in isoform 2)	Ubiquitination	-	34.45	21890473
666	Ubiquitination	INRLMAAKQKLRQLQ HHHHHHHHHHHHHHH	38.13	-
668	Ubiquitination	RLMAAKQKLRQLQDL HHHHHHHHHHHHHHH	44.95	-
690	Phosphorylation	DAAQGVISASASNLD HHHHHHHHHCCCCCH	17.48	27251275
692	Phosphorylation	AQGVISASASNLDDF HHHHHHHCCCCCHHC	25.99	29802988
694	Phosphorylation	GVISASASNLDDFYP HHHHHCCCCCHHCCC	35.12	29802988
700	Phosphorylation	ASNLDDFYPAEEDTK CCCCHHCCCCHHHCC	14.45	-
707	Ubiquitination	YPAEEDTKQNSNNTR CCCHHHCCCCCCCCC	60.86	-
707	Ubiquitination	YPAEEDTKQNSNNTR CCCHHHCCCCCCCCC	60.86	-
707 (in isoform 1)	Ubiquitination	-	60.86	21890473
707 (in isoform 2)	Ubiquitination	-	60.86	21890473
720	Phosphorylation	TRGNANKTQKDTGVN CCCCCCHHHCCCCCC	40.43	20068231
722	Ubiquitination	GNANKTQKDTGVNEK CCCCHHHCCCCCCHH	63.59	-
722	Ubiquitination	GNANKTQKDTGVNEK CCCCHHHCCCCCCHH	63.59	-
722 (in isoform 1)	Ubiquitination	-	63.59	21890473
722 (in isoform 2)	Ubiquitination	-	63.59	21890473
724	Phosphorylation	ANKTQKDTGVNEKAR CCHHHCCCCCCHHHH	50.49	20068231
729	Ubiquitination	KDTGVNEKAREKFYE CCCCCCHHHHHHHHH	47.76	-
729	Ubiquitination	KDTGVNEKAREKFYE CCCCCCHHHHHHHHH	47.76	-
729 (in isoform 1)	Ubiquitination	-	47.76	21890473
729 (in isoform 2)	Ubiquitination	-	47.76	21890473
733	Ubiquitination	VNEKAREKFYEAKLQ CCHHHHHHHHHHHHH	47.93	21890473
733	Ubiquitination	VNEKAREKFYEAKLQ CCHHHHHHHHHHHHH	47.93	-
733	Ubiquitination	VNEKAREKFYEAKLQ CCHHHHHHHHHHHHH	47.93	21890473
733 (in isoform 1)	Ubiquitination	-	47.93	21890473
733 (in isoform 2)	Ubiquitination	-	47.93	21890473
735	Phosphorylation	EKAREKFYEAKLQQQ HHHHHHHHHHHHHHH	26.50	28152594
738	Ubiquitination	REKFYEAKLQQQQRE HHHHHHHHHHHHHHH	34.58	21890473
738	Ubiquitination	REKFYEAKLQQQQRE HHHHHHHHHHHHHHH	34.58	-
738	Acetylation	REKFYEAKLQQQQRE HHHHHHHHHHHHHHH	34.58	25953088
738	Ubiquitination	REKFYEAKLQQQQRE HHHHHHHHHHHHHHH	34.58	21890473
738 (in isoform 1)	Ubiquitination	-	34.58	21890473
738 (in isoform 2)	Ubiquitination	-	34.58	21890473
746 (in isoform 3)	Ubiquitination	-	4.70	21890473
747	Ubiquitination	QQQQRELKQLQEERK HHHHHHHHHHHHHHH	44.18	-
747	Ubiquitination	QQQQRELKQLQEERK HHHHHHHHHHHHHHH	44.18	-
754	Ubiquitination	KQLQEERKKLIDIQE HHHHHHHHHHHHHHH	56.03	-
754	Ubiquitination	KQLQEERKKLIDIQE HHHHHHHHHHHHHHH	56.03	-
755	Ubiquitination	QLQEERKKLIDIQEK HHHHHHHHHHHHHHH	57.82	-
755	Ubiquitination	QLQEERKKLIDIQEK HHHHHHHHHHHHHHH	57.82	-
761 (in isoform 3)	Ubiquitination	-	53.08	21890473
762	Ubiquitination	KLIDIQEKIQALQTA HHHHHHHHHHHHHHH	24.60	-
762	Ubiquitination	KLIDIQEKIQALQTA HHHHHHHHHHHHHHH	24.60	-
768	Phosphorylation	EKIQALQTACPDLQL HHHHHHHHHCCCCCC	30.95	30576142
768 (in isoform 3)	Ubiquitination	-	30.95	21890473
776	Phosphorylation	ACPDLQLSAASVGNC HCCCCCCCHHHCCCC	14.61	25159151
777 (in isoform 3)	Ubiquitination	-	16.61	21890473
779	Phosphorylation	DLQLSAASVGNCPTK CCCCCHHHCCCCCCC	30.21	25159151
785	Phosphorylation	ASVGNCPTKKYMPAV HHCCCCCCCCCCCCC	42.22	21712546
786	Ubiquitination	SVGNCPTKKYMPAVT HCCCCCCCCCCCCCC	27.35	-
786	Acetylation	SVGNCPTKKYMPAVT HCCCCCCCCCCCCCC	27.35	25953088
786	Ubiquitination	SVGNCPTKKYMPAVT HCCCCCCCCCCCCCC	27.35	-
787	Ubiquitination	VGNCPTKKYMPAVTS CCCCCCCCCCCCCCC	49.62	21890473
787	Ubiquitination	VGNCPTKKYMPAVTS CCCCCCCCCCCCCCC	49.62	-
787	Ubiquitination	VGNCPTKKYMPAVTS CCCCCCCCCCCCCCC	49.62	21890473
787 (in isoform 1)	Ubiquitination	-	49.62	21890473
787 (in isoform 2)	Ubiquitination	-	49.62	21890473
788	Phosphorylation	GNCPTKKYMPAVTST CCCCCCCCCCCCCCC	15.19	29396449
793	Phosphorylation	KKYMPAVTSTPTVNQ CCCCCCCCCCCCCCC	29.05	28450419
794	Phosphorylation	KYMPAVTSTPTVNQH CCCCCCCCCCCCCCC	26.28	25159151
795	Phosphorylation	YMPAVTSTPTVNQHE CCCCCCCCCCCCCCC	17.39	25159151
797	Phosphorylation	PAVTSTPTVNQHETS CCCCCCCCCCCCCCC	31.98	21712546
803	Phosphorylation	PTVNQHETSTSKSVF CCCCCCCCCCCCCCC	34.87	25159151
804	Phosphorylation	TVNQHETSTSKSVFE CCCCCCCCCCCCCCC	27.91	25159151
805	Phosphorylation	VNQHETSTSKSVFEP CCCCCCCCCCCCCCC	47.82	25159151
806	Phosphorylation	NQHETSTSKSVFEPE CCCCCCCCCCCCCCC	23.77	25159151
807	Ubiquitination	QHETSTSKSVFEPED CCCCCCCCCCCCCCC	51.21	-
807	Ubiquitination	QHETSTSKSVFEPED CCCCCCCCCCCCCCC	51.21	-
807 (in isoform 1)	Ubiquitination	-	51.21	21890473
807 (in isoform 2)	Ubiquitination	-	51.21	21890473
808	Phosphorylation	HETSTSKSVFEPEDS CCCCCCCCCCCCCCC	31.63	20873877
815	Phosphorylation	SVFEPEDSSIVDNEL CCCCCCCCCCCCHHH	21.94	30108239
816	Phosphorylation	VFEPEDSSIVDNELW CCCCCCCCCCCHHHH	38.66	28122231
824	Phosphorylation	IVDNELWSEMRRHEM CCCHHHHHHHHHHHH	33.85	25159151
826 (in isoform 3)	Ubiquitination	-	3.68	21890473
841	Ubiquitination	EELRQRRKQLEALMA HHHHHHHHHHHHHHH	62.52	21890473
841	Ubiquitination	EELRQRRKQLEALMA HHHHHHHHHHHHHHH	62.52	-
841	Ubiquitination	EELRQRRKQLEALMA HHHHHHHHHHHHHHH	62.52	21890473
841 (in isoform 1)	Ubiquitination	-	62.52	21890473
841 (in isoform 2)	Ubiquitination	-	62.52	21890473
846 (in isoform 3)	Ubiquitination	-	2.14	21890473
859	Phosphorylation	RRQGLAETASPVAVS HHHCHHHCCCCEEEE	27.16	30266825
861	Phosphorylation	QGLAETASPVAVSLR HCHHHCCCCEEEEEC	27.59	19664994
866	Phosphorylation	TASPVAVSLRSDGSE CCCCEEEEECCCCCC	14.34	30266825
869	Phosphorylation	PVAVSLRSDGSENLC CEEEEECCCCCCCCC	52.17	29255136
872	Phosphorylation	VSLRSDGSENLCTPQ EEECCCCCCCCCCCC	28.44	29255136
877	Phosphorylation	DGSENLCTPQQSRTE CCCCCCCCCCCCCCC	27.57	29255136
880 (in isoform 3)	Ubiquitination	-	35.76	21890473
881	Phosphorylation	NLCTPQQSRTEKTMA CCCCCCCCCCCCCCC	35.60	29255136
883	Phosphorylation	CTPQQSRTEKTMATW CCCCCCCCCCCCCCC	47.26	26074081
894	Phosphorylation	MATWGGSTQCALDEE CCCCCCCCCEECCCC	30.83	28348404
909	Phosphorylation	GDEDGYLSEGIVRTD CCCCCCCCCCEECCC	25.87	26471730
950	Ubiquitination	SYNGKETKNRWKNNC CCCCCCCCCCCCCCC	45.68	-
954	Ubiquitination	KETKNRWKNNCPFSA CCCCCCCCCCCCCCC	34.74	21890473
954	Ubiquitination	KETKNRWKNNCPFSA CCCCCCCCCCCCCCC	34.74	-
954	Ubiquitination	KETKNRWKNNCPFSA CCCCCCCCCCCCCCC	34.74	21890473
954 (in isoform 1)	Ubiquitination	-	34.74	21890473
954 (in isoform 2)	Ubiquitination	-	34.74	21890473
960	Phosphorylation	WKNNCPFSADENYRP CCCCCCCCCCCCCHH	21.69	25159151
965	Phosphorylation	PFSADENYRPLAKTR CCCCCCCCHHCHHHH	16.15	25159151
970	Ubiquitination	ENYRPLAKTRQQNIS CCCHHCHHHHHHHHC	52.50	21890473
970	Ubiquitination	ENYRPLAKTRQQNIS CCCHHCHHHHHHHHC	52.50	-
970	Acetylation	ENYRPLAKTRQQNIS CCCHHCHHHHHHHHC	52.50	25953088
970	Ubiquitination	ENYRPLAKTRQQNIS CCCHHCHHHHHHHHC	52.50	21890473
970 (in isoform 1)	Ubiquitination	-	52.50	21890473
970 (in isoform 2)	Ubiquitination	-	52.50	21890473
971	Phosphorylation	NYRPLAKTRQQNISM CCHHCHHHHHHHHCH	28.27	29083192
977	Phosphorylation	KTRQQNISMQRQENL HHHHHHHCHHHHHHH	19.20	25159151
988	Phosphorylation	QENLRWVSELSYVEE HHHHHHHHHHHHHHH	26.34	30266825
991	Phosphorylation	LRWVSELSYVEEKEQ HHHHHHHHHHHHHHH	24.07	19664994
992	Phosphorylation	RWVSELSYVEEKEQW HHHHHHHHHHHHHHH	25.22	23663014
996	Ubiquitination	ELSYVEEKEQWQEQI HHHHHHHHHHHHHHH	41.52	-
996	Ubiquitination	ELSYVEEKEQWQEQI HHHHHHHHHHHHHHH	41.52	-
996 (in isoform 1)	Ubiquitination	-	41.52	21890473
996 (in isoform 2)	Ubiquitination	-	41.52	21890473
997	Ubiquitination	LSYVEEKEQWQEQIN HHHHHHHHHHHHHHH	61.40	21906983
1007	Ubiquitination	QEQINQLKKQLDFSV HHHHHHHHHHHHHHH	28.80	-
1007	Ubiquitination	QEQINQLKKQLDFSV HHHHHHHHHHHHHHH	28.80	21890473
1007 (in isoform 1)	Ubiquitination	-	28.80	21890473
1007 (in isoform 2)	Ubiquitination	-	28.80	21890473
1008	Ubiquitination	EQINQLKKQLDFSVS HHHHHHHHHHHHHHH	65.76	21906983
1035 (in isoform 3)	Ubiquitination	-	6.21	21890473
1046 (in isoform 3)	Ubiquitination	-	7.00	21890473
1076	Ubiquitination	QNNVQRLKQMLNELM HHHHHHHHHHHHHHH	35.53	21890473
1076	Ubiquitination	QNNVQRLKQMLNELM HHHHHHHHHHHHHHH	35.53	-
1076	Ubiquitination	QNNVQRLKQMLNELM HHHHHHHHHHHHHHH	35.53	21890473
1076 (in isoform 1)	Ubiquitination	-	35.53	21890473
1076 (in isoform 2)	Ubiquitination	-	35.53	21890473
1092	Ubiquitination	QQNQHPEKPGGKERG HHHCCCCCCCCCCCC	54.11	-
1092	Ubiquitination	QQNQHPEKPGGKERG HHHCCCCCCCCCCCC	54.11	-
1092 (in isoform 1)	Ubiquitination	-	54.11	21890473
1092 (in isoform 2)	Ubiquitination	-	54.11	21890473
1096	Ubiquitination	HPEKPGGKERGSSAS CCCCCCCCCCCCCCC	50.59	-
1096	Ubiquitination	HPEKPGGKERGSSAS CCCCCCCCCCCCCCC	50.59	-
1096 (in isoform 1)	Ubiquitination	-	50.59	21890473
1096 (in isoform 2)	Ubiquitination	-	50.59	21890473
1107	Phosphorylation	SSASHPPSPSLFCPF CCCCCCCCCCCCCCC	31.41	21552520
1115 (in isoform 3)	Ubiquitination	-	18.56	21890473
1131 (in isoform 3)	Ubiquitination	-	32.32	21890473
1135 (in isoform 3)	Ubiquitination	-	10.35	21890473
1157	Phosphorylation	GDFSQNISTPSEQQQ CCCCCCCCCCHHHHC	41.64	26074081
1158	Phosphorylation	DFSQNISTPSEQQQP CCCCCCCCCHHHHCC	27.34	26074081
1160	Phosphorylation	SQNISTPSEQQQPLA CCCCCCCHHHHCCCC	48.39	26074081
1174	Phosphorylation	AQNSSGKTEYMAFPK CCCCCCCCEEEECCC	35.55	27273156
1176	Phosphorylation	NSSGKTEYMAFPKPF CCCCCCEEEECCCCC	10.04	27273156
1181	Ubiquitination	TEYMAFPKPFESSSS CEEEECCCCCCCCCC	56.75	21890473
1181	Ubiquitination	TEYMAFPKPFESSSS CEEEECCCCCCCCCC	56.75	-
1181	Ubiquitination	TEYMAFPKPFESSSS CEEEECCCCCCCCCC	56.75	21890473
1181 (in isoform 1)	Ubiquitination	-	56.75	21890473
1181 (in isoform 2)	Ubiquitination	-	56.75	21890473
1185	Phosphorylation	AFPKPFESSSSIGAE ECCCCCCCCCCCCCC	35.58	23401153
1186	Phosphorylation	FPKPFESSSSIGAEK CCCCCCCCCCCCCCC	22.40	23401153
1187	Phosphorylation	PKPFESSSSIGAEKP CCCCCCCCCCCCCCC	34.94	29255136
1188	Phosphorylation	KPFESSSSIGAEKPR CCCCCCCCCCCCCCC	27.30	29255136
1193	Ubiquitination	SSSIGAEKPRNKKLP CCCCCCCCCCCCCCC	49.06	-
1193	Ubiquitination	SSSIGAEKPRNKKLP CCCCCCCCCCCCCCC	49.06	21139048
1193 (in isoform 1)	Ubiquitination	-	49.06	21890473
1193 (in isoform 2)	Ubiquitination	-	49.06	21890473
1197	Ubiquitination	GAEKPRNKKLPEEEV CCCCCCCCCCCHHHH	57.90	-
1197	Ubiquitination	GAEKPRNKKLPEEEV CCCCCCCCCCCHHHH	57.90	-
1197 (in isoform 1)	Ubiquitination	-	57.90	21890473
1197 (in isoform 2)	Ubiquitination	-	57.90	21890473
1198	Ubiquitination	AEKPRNKKLPEEEVE CCCCCCCCCCHHHHH	73.20	-
1198	Ubiquitination	AEKPRNKKLPEEEVE CCCCCCCCCCHHHHH	73.20	-
1198 (in isoform 1)	Ubiquitination	-	73.20	21890473
1198 (in isoform 2)	Ubiquitination	-	73.20	21890473
1206	Phosphorylation	LPEEEVESSRTPWLY CCHHHHHHCCCCCCE	30.23	29255136
1207	Phosphorylation	PEEEVESSRTPWLYE CHHHHHHCCCCCCEE	27.03	29255136
1209	Phosphorylation	EEVESSRTPWLYEQE HHHHHCCCCCCEEEC	22.29	28348404
1213	Phosphorylation	SSRTPWLYEQEGEVE HCCCCCCEEECCEEE	16.23	28796482
1220 (in isoform 3)	Ubiquitination	-	51.19	21890473
1221	Ubiquitination	EQEGEVEKPFIKTGF EECCEEECCEEECCE	50.86	21890473
1221	Ubiquitination	EQEGEVEKPFIKTGF EECCEEECCEEECCE	50.86	-
1221	Ubiquitination	EQEGEVEKPFIKTGF EECCEEECCEEECCE	50.86	21890473
1221 (in isoform 1)	Ubiquitination	-	50.86	21890473
1221 (in isoform 2)	Ubiquitination	-	50.86	21890473
1225	Ubiquitination	EVEKPFIKTGFSVSV EEECCEEECCEEEEE	42.87	-
1225	Ubiquitination	EVEKPFIKTGFSVSV EEECCEEECCEEEEE	42.87	-
1225 (in isoform 2)	Ubiquitination	-	42.87	-
1226	Phosphorylation	VEKPFIKTGFSVSVE EECCEEECCEEEEEE	38.35	30266825
1229	Phosphorylation	PFIKTGFSVSVEKST CEEECCEEEEEEECC	18.15	30266825
1231	Phosphorylation	IKTGFSVSVEKSTSS EECCEEEEEEECCCC	24.30	30266825
1232 (in isoform 3)	Ubiquitination	-	11.42	21890473
1234	Ubiquitination	GFSVSVEKSTSSNRK CEEEEEEECCCCCCC	57.80	-
1234	Ubiquitination	GFSVSVEKSTSSNRK CEEEEEEECCCCCCC	57.80	-
1236	Phosphorylation	SVSVEKSTSSNRKNQ EEEEEECCCCCCCCC	47.44	24719451
1236 (in isoform 3)	Ubiquitination	-	47.44	21890473
1237 (in isoform 3)	Ubiquitination	-	32.48	21890473
1241	Ubiquitination	KSTSSNRKNQLDTNG ECCCCCCCCCCCCCC	53.98	-
1246	Phosphorylation	NRKNQLDTNGRRRQF CCCCCCCCCCCCCCC	48.44	24719451
1256	Phosphorylation	RRRQFDEESLESFSS CCCCCCHHHHHHHHC	63.57	17081983
1257	Phosphorylation	RRQFDEESLESFSSM CCCCCHHHHHHHHCC	35.08	23927012
1259	Phosphorylation	QFDEESLESFSSMPD CCCHHHHHHHHCCCC	60.04	17081983
1260	Phosphorylation	FDEESLESFSSMPDP CCHHHHHHHHCCCCC	35.40	23927012
1260 (in isoform 3)	Ubiquitination	-	35.40	21890473
1262	Phosphorylation	EESLESFSSMPDPVD HHHHHHHHCCCCCCC	34.70	23927012
1263	Phosphorylation	ESLESFSSMPDPVDP HHHHHHHCCCCCCCC	32.12	23927012
1271	Phosphorylation	MPDPVDPTTVTKTFK CCCCCCCCCCCCCHH	29.45	23927012
1272	Phosphorylation	PDPVDPTTVTKTFKT CCCCCCCCCCCCHHC	31.40	23927012
1274	Phosphorylation	PVDPTTVTKTFKTRK CCCCCCCCCCHHCCH	23.44	30108239
1275	Ubiquitination	VDPTTVTKTFKTRKA CCCCCCCCCHHCCHH	47.86	-
1275	Ubiquitination	VDPTTVTKTFKTRKA CCCCCCCCCHHCCHH	47.86	-
1275 (in isoform 1)	Ubiquitination	-	47.86	21890473
1275 (in isoform 2)	Ubiquitination	-	47.86	21890473
1281	Ubiquitination	TKTFKTRKASAQASL CCCHHCCHHHHHHHH	52.50	-
1283	Phosphorylation	TFKTRKASAQASLAS CHHCCHHHHHHHHHC	24.77	25159151
1287	Phosphorylation	RKASAQASLASKDKT CHHHHHHHHHCCCCC	16.64	23927012
1290	Phosphorylation	SAQASLASKDKTPKS HHHHHHHCCCCCCCC	46.83	25159151
1291	Ubiquitination	AQASLASKDKTPKSK HHHHHHCCCCCCCCH	58.60	-
1291	Ubiquitination	AQASLASKDKTPKSK HHHHHHCCCCCCCCH	58.60	-
1291 (in isoform 1)	Ubiquitination	-	58.60	21890473
1291 (in isoform 2)	Ubiquitination	-	58.60	21890473
1294	Phosphorylation	SLASKDKTPKSKSKK HHHCCCCCCCCHHCC	46.19	27422710
1296	Ubiquitination	ASKDKTPKSKSKKRN HCCCCCCCCHHCCCC	75.61	-
1296	Ubiquitination	ASKDKTPKSKSKKRN HCCCCCCCCHHCCCC	75.61	-
1297	Phosphorylation	SKDKTPKSKSKKRNS CCCCCCCCHHCCCCH	43.28	26074081
1299	Phosphorylation	DKTPKSKSKKRNSTQ CCCCCCHHCCCCHHH	50.96	26074081
1304	Phosphorylation	SKSKKRNSTQLKSRV CHHCCCCHHHHHHHH	22.89	26699800
1305	Phosphorylation	KSKKRNSTQLKSRVK HHCCCCHHHHHHHHH	41.28	30576142
1308	Ubiquitination	KRNSTQLKSRVKNIR CCCHHHHHHHHHHHH	26.80	-
1309	Phosphorylation	RNSTQLKSRVKNIRY CCHHHHHHHHHHHHH	51.39	26074081
1314 (in isoform 3)	Ubiquitination	-	4.04	21890473
1316	Phosphorylation	SRVKNIRYESASMSS HHHHHHHHHHCCCCC	15.50	28450419
1316 (in isoform 2)	Phosphorylation	-	15.50	22210691
1317	Phosphorylation	RVKNIRYESASMSST HHHHHHHHHCCCCCC	29.94	22210691
1318	Phosphorylation	VKNIRYESASMSSTC HHHHHHHHCCCCCCC	19.40	28450419
1318 (in isoform 2)	Phosphorylation	-	19.40	20873877
1319	Phosphorylation	KNIRYESASMSSTCE HHHHHHHCCCCCCCC	9.41	20873877
1319	Phosphorylation	KNIRYESASMSSTCE HHHHHHHCCCCCCCC	9.41	20873877
1320	Phosphorylation	NIRYESASMSSTCEP HHHHHHCCCCCCCCC	28.60	21815630
1321 (in isoform 2)	Phosphorylation	-	3.52	28111955
1322	Phosphorylation	RYESASMSSTCEPCK HHHHCCCCCCCCCCC	21.72	28111955
1322	Phosphorylation	RYESASMSSTCEPCK HHHHCCCCCCCCCCC	21.72	28450419
1323	Phosphorylation	YESASMSSTCEPCKS HHHCCCCCCCCCCCC	28.56	30576142
1324	Phosphorylation	ESASMSSTCEPCKSR HHCCCCCCCCCCCCC	17.37	28450419
1329	Ubiquitination	SSTCEPCKSRNRHSA CCCCCCCCCCCCCCC	64.27	-
1329	Ubiquitination	SSTCEPCKSRNRHSA CCCCCCCCCCCCCCC	64.27	-
1330 (in isoform 3)	Ubiquitination	-	41.32	21890473
1335	Phosphorylation	CKSRNRHSAQTEEPV CCCCCCCCCCCCCCH	20.87	23401153
1338	Phosphorylation	RNRHSAQTEEPVQAK CCCCCCCCCCCHHHH	41.87	29116813
1345	Ubiquitination	TEEPVQAKVFSRKNH CCCCHHHHHHCCCCH	27.07	21890473
1345	Ubiquitination	TEEPVQAKVFSRKNH CCCCHHHHHHCCCCH	27.07	21890473
1345 (in isoform 1)	Ubiquitination	-	27.07	21890473
1348	Phosphorylation	PVQAKVFSRKNHEQL CHHHHHHCCCCHHHH	45.38	-
1350	Ubiquitination	QAKVFSRKNHEQLEK HHHHHCCCCHHHHHH	62.55	-
1357	Ubiquitination	KNHEQLEKIIKCNRS CCHHHHHHHHHCCCC	59.32	-
1364	Phosphorylation	KIIKCNRSTEISSET HHHHCCCCCCCCCCC	19.19	27732954
1365	Phosphorylation	IIKCNRSTEISSETG HHHCCCCCCCCCCCC	33.82	27732954
1368	Phosphorylation	CNRSTEISSETGSDF CCCCCCCCCCCCCCC	18.85	30108239
1369	Phosphorylation	NRSTEISSETGSDFS CCCCCCCCCCCCCCH	44.85	30108239
1371	Phosphorylation	STEISSETGSDFSMF CCCCCCCCCCCCHHH	43.89	30108239
1373	Phosphorylation	EISSETGSDFSMFEA CCCCCCCCCCHHHHH	42.79	22617229
1376	Phosphorylation	SETGSDFSMFEALRD CCCCCCCHHHHHHHH	27.79	25850435
1384 (in isoform 3)	Ubiquitination	-	18.51	21890473
1385 (in isoform 2)	Ubiquitination	-	4.11	21890473
1398	Phosphorylation	TLISQNESRPHFLIE HHHHCCCCCCCHHHH	59.67	23828894
1424	Phosphorylation	YLRQRALYALQDIVS HHHHHHHHHHHHHHH	12.32	25839225
1435	Phosphorylation	DIVSRHISESHEKGE HHHHHHCHHHHHCCC	27.24	26657352
1437	Phosphorylation	VSRHISESHEKGENV HHHHCHHHHHCCCCC	30.10	29116813
1440	Ubiquitination	HISESHEKGENVKSV HCHHHHHCCCCCCCC	67.13	-
1440 (in isoform 1)	Ubiquitination	-	67.13	21890473
1449	Phosphorylation	ENVKSVNSGTWIASN CCCCCCCCCCEEECC	35.13	27690223
1451	Phosphorylation	VKSVNSGTWIASNSE CCCCCCCCEEECCCC	17.33	27251275
1455	Phosphorylation	NSGTWIASNSELTPS CCCCEEECCCCCCCC	31.58	27251275
1457	Phosphorylation	GTWIASNSELTPSES CCEEECCCCCCCCHH	31.33	25159151
1460	Phosphorylation	IASNSELTPSESLAT EECCCCCCCCHHCCC	22.25	25159151
1462	Phosphorylation	SNSELTPSESLATTD CCCCCCCCHHCCCCC	34.28	27251275
1464	Phosphorylation	SELTPSESLATTDDE CCCCCCHHCCCCCHH	27.86	27251275
1467	Phosphorylation	TPSESLATTDDETFE CCCHHCCCCCHHHHH	35.73	25159151
1468	Phosphorylation	PSESLATTDDETFEK CCHHCCCCCHHHHHH	35.53	25159151
1472	Phosphorylation	LATTDDETFEKNFER CCCCCHHHHHHHHHH	44.05	27251275
1476 (in isoform 2)	Ubiquitination	-	36.49	21890473
1479 (in isoform 3)	Ubiquitination	-	50.40	21890473
1481	Phosphorylation	EKNFERETHKISEQN HHHHHHHHHCCCCCC	34.39	26074081
1485	Phosphorylation	ERETHKISEQNDADN HHHHHCCCCCCCCCC	37.62	21082442
1493	Phosphorylation	EQNDADNASVLSVSS CCCCCCCCCEEEEEC	11.10	17081983
1494	Phosphorylation	QNDADNASVLSVSSN CCCCCCCCEEEEECC	29.82	21082442
1496	Phosphorylation	DADNASVLSVSSNFE CCCCCCEEEEECCCC	3.76	17081983
1497	Phosphorylation	ADNASVLSVSSNFEP CCCCCEEEEECCCCC	20.14	25159151
1498	Phosphorylation	DNASVLSVSSNFEPF CCCCEEEEECCCCCC	6.77	17081983
1499	Phosphorylation	NASVLSVSSNFEPFA CCCEEEEECCCCCCC	19.05	25159151
1500	Phosphorylation	ASVLSVSSNFEPFAT CCEEEEECCCCCCCC	43.30	25159151
1507	Phosphorylation	SNFEPFATDDLGNTV CCCCCCCCCCCCCCE	30.35	28464451
1513	Phosphorylation	ATDDLGNTVIHLDQA CCCCCCCCEEHHHHH	21.02	20873877
1527	Phosphorylation	ALARMREYERMKTEA HHHHHHHHHHHHHHH	9.85	-
1531	Ubiquitination	MREYERMKTEAESNS HHHHHHHHHHHHHCC	49.81	-
1531 (in isoform 1)	Ubiquitination	-	49.81	21890473
1532	Phosphorylation	REYERMKTEAESNSN HHHHHHHHHHHHCCC	30.96	-
1543	Phosphorylation	SNSNMRCTCRIIEDG HCCCCCEEEEEEECC	8.41	-
1547 (in isoform 2)	Ubiquitination	-	1.72	21890473
1557	Phosphorylation	GDGAGAGTTVNNLEE CCCCCCCCCCCCCCC	27.34	28355574
1557	Phosphorylation	GDGAGAGTTVNNLEE CCCCCCCCCCCCCCC	27.34	25627689
1558	Phosphorylation	DGAGAGTTVNNLEET CCCCCCCCCCCCCCC	21.96	28348404
1565	Phosphorylation	TVNNLEETPVIENRS CCCCCCCCCCCCCCC	17.30	28985074
1570	Phosphorylation	EETPVIENRSSQQPV CCCCCCCCCCCCCCC	37.70	25627689
1570	Phosphorylation	EETPVIENRSSQQPV CCCCCCCCCCCCCCC	37.70	25627689
1570 (in isoform 3)	Ubiquitination	-	37.70	21890473
1572	Phosphorylation	TPVIENRSSQQPVSE CCCCCCCCCCCCCCC	44.04	29083192
1573	Phosphorylation	PVIENRSSQQPVSEV CCCCCCCCCCCCCCC	29.60	28555341
1578	Phosphorylation	RSSQQPVSEVSTIPC CCCCCCCCCCCCCCC	38.68	25159151
1581	Phosphorylation	QQPVSEVSTIPCPRI CCCCCCCCCCCCCCC	19.30	28555341
1582	Phosphorylation	QPVSEVSTIPCPRID CCCCCCCCCCCCCCC	33.83	24043423
1584 (in isoform 2)	Ubiquitination	-	23.34	21890473
1590	Phosphorylation	IPCPRIDTQQLDRQI CCCCCCCHHHHHHHH	18.82	-
1592 (in isoform 2)	Ubiquitination	-	47.63	21890473
1595	Methylation	IDTQQLDRQIKAIMK CCHHHHHHHHHHHHH	49.03	115486647
1602	Ubiquitination	RQIKAIMKEVIPFLK HHHHHHHHHHHHHHH	42.59	21890473
1602 (in isoform 1)	Ubiquitination	-	42.59	21890473
1604 (in isoform 2)	Ubiquitination	-	5.86	21890473
1609	Ubiquitination	KEVIPFLKEHMDEVC HHHHHHHHHHHHHHH	46.05	-
1639	Ubiquitination	TQQNDESKEFVKFFH HHCCHHHHHHHHHHH	53.80	-
1639 (in isoform 1)	Ubiquitination	-	53.80	21890473
1641 (in isoform 3)	Ubiquitination	-	9.23	21890473
1643	Ubiquitination	DESKEFVKFFHKQLG HHHHHHHHHHHHHHH	47.86	-
1646 (in isoform 2)	Ubiquitination	-	21.78	21890473
1647	Ubiquitination	EFVKFFHKQLGSILQ HHHHHHHHHHHHHHH	41.90	21890473
1647	Ubiquitination	EFVKFFHKQLGSILQ HHHHHHHHHHHHHHH	41.90	21890473
1647 (in isoform 1)	Ubiquitination	-	41.90	21890473
1651	Phosphorylation	FFHKQLGSILQDSLA HHHHHHHHHHHHHHH	28.81	21406692
1656	Phosphorylation	LGSILQDSLAKFAGR HHHHHHHHHHHHCCH	19.77	21406692
1659	Ubiquitination	ILQDSLAKFAGRKLK HHHHHHHHHCCHHHH	40.83	21890473
1659	Ubiquitination	ILQDSLAKFAGRKLK HHHHHHHHHCCHHHH	40.83	21890473
1659 (in isoform 1)	Ubiquitination	-	40.83	21890473
1678 (in isoform 3)	Ubiquitination	-	49.23	21890473
1697	Phosphorylation	MQDLDNNSITVKQRC HHHCCCCCCCHHHHH	26.37	25159151
1698 (in isoform 3)	Ubiquitination	-	5.81	21890473
1699	Phosphorylation	DLDNNSITVKQRCKR HCCCCCCCHHHHHHH	22.82	20068231
1701	Ubiquitination	DNNSITVKQRCKRKI CCCCCCHHHHHHHHH	24.31	21890473
1701	Ubiquitination	DNNSITVKQRCKRKI CCCCCCHHHHHHHHH	24.31	21890473
1701 (in isoform 1)	Ubiquitination	-	24.31	21890473
1707	Ubiquitination	VKQRCKRKIEATGVI HHHHHHHHHHHHHHH	30.32	-
1716	Phosphorylation	EATGVIQSCAKEAKR HHHHHHHHHHHHHHH	12.62	25159151
1719	Acetylation	GVIQSCAKEAKRILE HHHHHHHHHHHHHHH	63.63	25953088
1719	Ubiquitination	GVIQSCAKEAKRILE HHHHHHHHHHHHHHH	63.63	-
1722	Ubiquitination	QSCAKEAKRILEDHG HHHHHHHHHHHHHCC	40.85	-
1729	Phosphorylation	KRILEDHGSPAGEID HHHHHHCCCCCCCCC	47.88	17081983
1730	Phosphorylation	RILEDHGSPAGEIDD HHHHHCCCCCCCCCC	14.25	29255136
1740 (in isoform 3)	Ubiquitination	-	65.71	21890473
1745	Phosphorylation	EDKDKDETETVKQTQ CCCCCCCCCCCHHCC	47.27	20873877
1747	Phosphorylation	KDKDETETVKQTQTS CCCCCCCCCHHCCCC	40.18	20873877
1749	Ubiquitination	KDETETVKQTQTSEV CCCCCCCHHCCCCCC	55.86	-
1751	Phosphorylation	ETETVKQTQTSEVYD CCCCCHHCCCCCCCC	28.26	23312004
1753	Phosphorylation	ETVKQTQTSEVYDGP CCCHHCCCCCCCCCC	30.18	29978859
1754	Phosphorylation	TVKQTQTSEVYDGPK CCHHCCCCCCCCCCC	18.43	28985074
1757	Phosphorylation	QTQTSEVYDGPKNVR HCCCCCCCCCCCCCC	15.90	28796482
1761	Ubiquitination	SEVYDGPKNVRSDIS CCCCCCCCCCCCCCC	73.86	-
1764	Phosphorylation	YDGPKNVRSDISDQE CCCCCCCCCCCCCCC	37.70	17081983
1765	Phosphorylation	DGPKNVRSDISDQEE CCCCCCCCCCCCCCC	34.71	23927012
1767	Phosphorylation	PKNVRSDISDQEEDE CCCCCCCCCCCCCCH	5.29	17081983
1768	Phosphorylation	KNVRSDISDQEEDEE CCCCCCCCCCCCCHH	37.93	23927012
1776	Phosphorylation	DQEEDEESEGCPVSI CCCCCHHHCCCCEEE	36.92	25159151
1782	Phosphorylation	ESEGCPVSINLSKAE HHCCCCEEEECCHHH	7.30	23927012
1786	Phosphorylation	CPVSINLSKAETQAL CCEEEECCHHHHHHH	25.90	25159151
1794	Phosphorylation	KAETQALTNYGSGED HHHHHHHHCCCCCCC	29.43	-
1795 (in isoform 2)	Ubiquitination	-	39.76	21890473
1796	Phosphorylation	ETQALTNYGSGEDEN HHHHHHCCCCCCCCC	13.87	-
1798	Phosphorylation	QALTNYGSGEDENED HHHHCCCCCCCCCCH	28.75	-
1845	Ubiquitination	VLQRDFKKTAESKNV HHHHHHHHHHHHCCC	53.62	-
1850	Ubiquitination	FKKTAESKNVPLERE HHHHHHHCCCCCCHH	54.17	-
1850 (in isoform 1)	Ubiquitination	-	54.17	21890473
1859	Phosphorylation	VPLEREATSKNDQNN CCCCHHCCCCCCCCC	35.17	-
1860	Phosphorylation	PLEREATSKNDQNNC CCCHHCCCCCCCCCC	36.19	-
1861	Ubiquitination	LEREATSKNDQNNCP CCHHCCCCCCCCCCC	61.25	-
1870	Ubiquitination	DQNNCPVKPCYLNIL CCCCCCCCCCEEEHH	17.95	-
1873	Phosphorylation	NCPVKPCYLNILEDE CCCCCCCEEEHHCCC	16.00	28796482
1885	Phosphorylation	EDEQPLNSAAHKESP CCCCCCCCCCCCCCC	34.22	26657352
1889 (in isoform 3)	Ubiquitination	-	55.98	21890473
1891	Phosphorylation	NSAAHKESPPTVDST CCCCCCCCCCCCCCC	40.77	25849741
1894	Phosphorylation	AHKESPPTVDSTQQP CCCCCCCCCCCCCCC	40.09	21815630
1897	Phosphorylation	ESPPTVDSTQQPNPL CCCCCCCCCCCCCCC	24.63	25159151
1898	Phosphorylation	SPPTVDSTQQPNPLP CCCCCCCCCCCCCCC	27.10	25159151
1923	Phosphorylation	PRVKEVKSAQETPES CCHHHHHCHHCCCCH	40.12	26471730
1927	Phosphorylation	EVKSAQETPESSLAG HHHCHHCCCCHHCCC	21.92	25921289
1930	Phosphorylation	SAQETPESSLAGSPD CHHCCCCHHCCCCCC	31.68	29496963
1931	Phosphorylation	AQETPESSLAGSPDT HHCCCCHHCCCCCCC	22.15	29496963
1935	Phosphorylation	PESSLAGSPDTESPV CCHHCCCCCCCCCCE	17.62	25921289
1938	Phosphorylation	SLAGSPDTESPVLVN HCCCCCCCCCCEEEC	41.57	26657352
1940	Phosphorylation	AGSPDTESPVLVNDY CCCCCCCCCEEECEE	23.54	26657352
1947	Phosphorylation	SPVLVNDYEAESGNI CCEEECEEECCCCCC	16.31	28796482
1951	Phosphorylation	VNDYEAESGNISQKS ECEEECCCCCCCCCC	44.16	28796482
1955	Phosphorylation	EAESGNISQKSDEED ECCCCCCCCCCCHHH	35.24	30576142
1958	Phosphorylation	SGNISQKSDEEDFVK CCCCCCCCCHHHCEE	42.49	30266825
1965	Ubiquitination	SDEEDFVKVEDLPLK CCHHHCEEHHHCCEE	39.64	-
1974	Phosphorylation	EDLPLKLTIYSEADL HHCCEEEEEEEHHHH	19.11	23186163
1976	Phosphorylation	LPLKLTIYSEADLRK CCEEEEEEEHHHHHH	8.67	28796482
1977	Phosphorylation	PLKLTIYSEADLRKK CEEEEEEEHHHHHHH	23.58	25693802
2010	Phosphorylation	TEELAGNSETLKEPE HHHHCCCCCCCCCCC	30.92	30108239
2012	Phosphorylation	ELAGNSETLKEPETV HHCCCCCCCCCCCCC	42.84	30108239
2018	Phosphorylation	ETLKEPETVGAQSI- CCCCCCCCCCCCCC-	34.65	27251275
2023	Phosphorylation	PETVGAQSI------ CCCCCCCCC------	29.72	25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
372	S	Phosphorylation	Kinase	PLK4	O00444	PSP
-	K	Ubiquitination	E3 ubiquitin ligase	MIB1	Q86YT6	PMID:24121310

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
159	S	Phosphorylation	Variant Ser-159 is phosphorylated.	8120099
372	S	Phosphorylation	Phosphorylation at Ser-372 mediated by PLK4 is required to maintain the integrity of centriolar satellites.	23186163

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PCM1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ING5_HUMAN	ING5	physical	16189514
ECM29_HUMAN	KIAA0368	physical	16189514
WASC3_HUMAN	CCDC53	physical	16189514
ABI2_HUMAN	ABI2	physical	16189514
EXOC8_HUMAN	EXOC8	physical	16189514
CEP72_HUMAN	CEP72	physical	16189514
PCNT_HUMAN	PCNT	physical	11171385
EWS_HUMAN	EWSR1	physical	21956701
HNRL1_HUMAN	HNRNPUL1	physical	21956701
CLH1_HUMAN	CLTC	physical	21956701
MIB1_HUMAN	MIB1	physical	21956701
FUS_HUMAN	FUS	physical	21956701
CP131_HUMAN	CEP131	physical	21956701
PPIB_HUMAN	PPIB	physical	21956701
CEP72_HUMAN	CEP72	physical	19447967
WASC3_HUMAN	CCDC53	physical	25416956
MIB1_HUMAN	MIB1	physical	25795303
CE162_HUMAN	CEP162	physical	26638075
FTM_HUMAN	RPGRIP1L	physical	26638075
CP131_HUMAN	CEP131	physical	26638075
CC138_HUMAN	CCDC138	physical	26638075
CE170_HUMAN	CEP170	physical	26638075
HERC2_HUMAN	HERC2	physical	26638075
MED4_HUMAN	MED4	physical	26638075
MIB1_HUMAN	MIB1	physical	26638075
OFD1_HUMAN	OFD1	physical	26638075
PCNT_HUMAN	PCNT	physical	26638075
PIBF1_HUMAN	PIBF1	physical	26638075
ADIP_HUMAN	SSX2IP	physical	26638075
WRP73_HUMAN	WRAP73	physical	26638075
CSPP1_HUMAN	CSPP1	physical	26638075
HAUS1_HUMAN	HAUS1	physical	26638075
HAUS4_HUMAN	HAUS4	physical	26638075
MOONR_HUMAN	KIAA0753	physical	26638075
CEP72_HUMAN	CEP72	physical	26638075
CCD77_HUMAN	CCDC77	physical	26638075
CCNB2_HUMAN	CCNB2	physical	26638075
CE350_HUMAN	CEP350	physical	26638075
CEP95_HUMAN	CEP95	physical	26638075
KC1A_HUMAN	CSNK1A1	physical	26638075
DESP_HUMAN	DSP	physical	26638075
KI20A_HUMAN	KIF20A	physical	26638075
LUZP1_HUMAN	LUZP1	physical	26638075
MCM10_HUMAN	MCM10	physical	26638075
MCRS1_HUMAN	MCRS1	physical	26638075
MPRIP_HUMAN	MPRIP	physical	26638075
NDC80_HUMAN	NDC80	physical	26638075
SMRD2_HUMAN	SMARCD2	physical	26638075
TPGS1_HUMAN	TPGS1	physical	26638075
SPT5H_HUMAN	SUPT5H	physical	26638075
SSBP_HUMAN	SSBP1	physical	26638075
KIF7_HUMAN	KIF7	physical	26638075
SKA1_HUMAN	SKA1	physical	26638075
TSYL1_HUMAN	TSPYL1	physical	26638075
SR1IP_HUMAN	SREK1IP1	physical	26638075
KC1D_HUMAN	CSNK1D	physical	26638075
IF172_HUMAN	IFT172	physical	26638075
CEP55_HUMAN	CEP55	physical	26638075
IFT20_HUMAN	IFT20	physical	26638075
IFT81_HUMAN	IFT81	physical	26638075
CCD14_HUMAN	CCDC14	physical	26638075
HMMR_HUMAN	HMMR	physical	26638075
CFA97_HUMAN	CFAP97	physical	26638075
IPO5_HUMAN	IPO5	physical	26638075
KCD12_HUMAN	KCTD12	physical	26638075
RUXE_HUMAN	SNRPE	physical	26638075
ABCD3_HUMAN	ABCD3	physical	26638075
ACOT9_HUMAN	ACOT9	physical	26638075
ATP5L_HUMAN	ATP5L	physical	26638075
CAMP1_HUMAN	CAMSAP1	physical	26638075
C2D1A_HUMAN	CC2D1A	physical	26638075
CCD66_HUMAN	CCDC66	physical	26638075
CE120_HUMAN	CEP120	physical	26638075
CKAP2_HUMAN	CKAP2	physical	26638075
FR1OP_HUMAN	FGFR1OP	physical	26638075
HAUS2_HUMAN	HAUS2	physical	26638075
HAUS3_HUMAN	HAUS3	physical	26638075
HAUS5_HUMAN	HAUS5	physical	26638075
HAUS6_HUMAN	HAUS6	physical	26638075
HAUS7_HUMAN	HAUS7	physical	26638075
HAUS8_HUMAN	HAUS8	physical	26638075
IDH3B_HUMAN	IDH3B	physical	26638075
IFT57_HUMAN	IFT57	physical	26638075
IFT74_HUMAN	IFT74	physical	26638075
NCK5L_HUMAN	NCKAP5L	physical	26638075
RAE1L_HUMAN	RAE1	physical	26638075
STAU1_HUMAN	STAU1	physical	26638075
ASPP2_HUMAN	TP53BP2	physical	26638075
TTK_HUMAN	TTK	physical	26638075
TXLNA_HUMAN	TXLNA	physical	26638075
TXLNG_HUMAN	TXLNG	physical	26638075
TBC31_HUMAN	TBC1D31	physical	26638075
WDR83_HUMAN	WDR83	physical	26638075
XRN1_HUMAN	XRN1	physical	26638075
Z280C_HUMAN	ZNF280C	physical	26638075
ARP2_HUMAN	ACTR2	physical	26638075
ANR26_HUMAN	ANKRD26	physical	26638075
BAIP2_HUMAN	BAIAP2	physical	26638075
BICD1_HUMAN	BICD1	physical	26638075
BICD2_HUMAN	BICD2	physical	26638075
BTF3_HUMAN	BTF3	physical	26638075
CK049_HUMAN	C11orf49	physical	26638075
SKAP_HUMAN	KNSTRN	physical	26638075
C2CD3_HUMAN	C2CD3	physical	26638075
CAMP2_HUMAN	CAMSAP2	physical	26638075
CC112_HUMAN	CCDC112	physical	26638075
CCD18_HUMAN	CCDC18	physical	26638075
CCD22_HUMAN	CCDC22	physical	26638075
CC85C_HUMAN	CCDC85C	physical	26638075
CCD92_HUMAN	CCDC92	physical	26638075
CCNB1_HUMAN	CCNB1	physical	26638075
CP110_HUMAN	CCP110	physical	26638075
CD123_HUMAN	CDC123	physical	26638075
CE164_HUMAN	CEP164	physical	26638075
CE57L_HUMAN	CEP57L1	physical	26638075
CEP63_HUMAN	CEP63	physical	26638075
CEP85_HUMAN	CEP85	physical	26638075
CEP89_HUMAN	CEP89	physical	26638075
CEP97_HUMAN	CEP97	physical	26638075
CKP2L_HUMAN	CKAP2L	physical	26638075
CNO10_HUMAN	CNOT10	physical	26638075
COMD2_HUMAN	COMMD2	physical	26638075
COMD4_HUMAN	COMMD4	physical	26638075
KC1E_HUMAN	CSNK1E	physical	26638075
DAPK3_HUMAN	DAPK3	physical	26638075
DIAP3_HUMAN	DIAPH3	physical	26638075
RB6I2_HUMAN	ERC1	physical	26638075
EXOC4_HUMAN	EXOC4	physical	26638075
FOPNL_HUMAN	FOPNL	physical	26638075
GNAO_HUMAN	GNAO1	physical	26638075
GPTC1_HUMAN	GPATCH1	physical	26638075
IBTK_HUMAN	IBTK	physical	26638075
IQCB1_HUMAN	IQCB1	physical	26638075
K1328_HUMAN	KIAA1328	physical	26638075
KIF14_HUMAN	KIF14	physical	26638075
LCA5_HUMAN	LCA5	physical	26638075
LRC49_HUMAN	LRRC49	physical	26638075
LRCC1_HUMAN	LRRCC1	physical	26638075
MAGD1_HUMAN	MAGED1	physical	26638075
MA7D3_HUMAN	MAP7D3	physical	26638075
MED29_HUMAN	MED29	physical	26638075
MS18A_HUMAN	MIS18A	physical	26638075
M18BP_HUMAN	MIS18BP1	physical	26638075
PHOCN_HUMAN	MOB4	physical	26638075
MPP9_HUMAN	MPHOSPH9	physical	26638075
MYO9A_HUMAN	MYO9A	physical	26638075
NAV1_HUMAN	NAV1	physical	26638075
NEDD1_HUMAN	NEDD1	physical	26638075
NDK7_HUMAN	NME7	physical	26638075
NOL11_HUMAN	NOL11	physical	26638075
NUF2_HUMAN	NUF2	physical	26638075
ODF2L_HUMAN	ODF2L	physical	26638075
ODFP2_HUMAN	ODF2	physical	26638075
PCBP3_HUMAN	PCBP3	physical	26638075
PKN2_HUMAN	PKN2	physical	26638075
PLK1_HUMAN	PLK1	physical	26638075
KIZ_HUMAN	KIZ	physical	26638075
NEB2_HUMAN	PPP1R9B	physical	26638075
IFT22_HUMAN	IFT22	physical	26638075
RIR2_HUMAN	RRM2	physical	26638075
SCLT1_HUMAN	SCLT1	physical	26638075
SDCG3_HUMAN	SDCCAG3	physical	26638075
SEBP2_HUMAN	SECISBP2	physical	26638075
SMG5_HUMAN	SMG5	physical	26638075
SMG7_HUMAN	SMG7	physical	26638075
SPA24_HUMAN	SPATA24	physical	26638075
SPAS2_HUMAN	SPATS2	physical	26638075
SPC24_HUMAN	SPC24	physical	26638075
SPICE_HUMAN	SPICE1	physical	26638075
SRGP2_HUMAN	SRGAP2	physical	26638075
STRN4_HUMAN	STRN4	physical	26638075
TANC1_HUMAN	TANC1	physical	26638075
TCHP_HUMAN	TCHP	physical	26638075
TEX9_HUMAN	TEX9	physical	26638075
TNIP1_HUMAN	TNIP1	physical	26638075
MIPT3_HUMAN	TRAF3IP1	physical	26638075
TTC12_HUMAN	TTC12	physical	26638075
TTF2_HUMAN	TTF2	physical	26638075
TTLL4_HUMAN	TTLL4	physical	26638075
TTLL5_HUMAN	TTLL5	physical	26638075
CENPJ_HUMAN	CENPJ	physical	26638075

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 188550: Thyroid papillary carcinoma (TPC)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Lysine acetylation targets protein complexes and co-regulates majorcellular functions.";
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.;
Science 325:834-840(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-399, AND MASS SPECTROMETRY.
PubMed: 19608861

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-65; SER-68; SER-69;SER-93; SER-110; SER-116; SER-119; SER-1185; SER-1257; SER-1373;SER-1697; SER-1765; SER-1768; SER-1776 AND SER-1977, AND MASSSPECTROMETRY.
PubMed: 19690332

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-61; SER-65; SER-68;SER-69; SER-110; SER-159; SER-861; SER-872; SER-1185; SER-1187;SER-1188; SER-1765; SER-1768; SER-1776 AND SER-2023, AND MASSSPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-65; SER-68; SER-69;SER-93; SER-110; SER-960; SER-1231; SER-1257; SER-1260; SER-1262;SER-1730; SER-1765; SER-1768 AND SER-1776, AND MASS SPECTROMETRY.
PubMed: 18669648

"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-65, AND MASSSPECTROMETRY.
PubMed: 18187866

"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis.";
Wang B., Malik R., Nigg E.A., Korner R.;
Anal. Chem. 80:9526-9533(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-372, AND MASSSPECTROMETRY.
PubMed: 19007248

"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage.";
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.;
Science 316:1160-1166(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-356, AND MASSSPECTROMETRY.
PubMed: 17525332

"Phosphoproteome analysis of the human mitotic spindle.";
Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.;
Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-65; SER-69 AND SER-991,AND MASS SPECTROMETRY.
PubMed: 16565220

"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization.";
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
Nat. Biotechnol. 24:1285-1292(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-65; SER-68; SER-69 ANDTHR-877, AND MASS SPECTROMETRY.
PubMed: 16964243

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-65; SER-68; SER-69;SER-110; SER-431; SER-861; SER-866; SER-869; SER-872; SER-1730;SER-1765; SER-1768 AND SER-1776, AND MASS SPECTROMETRY.
PubMed: 17081983

"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-65, AND MASSSPECTROMETRY.
PubMed: 15302935