CE350_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CE350_HUMAN
• UniProt AC: Q5VT06
• Protein Name: Centrosome-associated protein 350 {ECO:0000305}
• Gene Name: CEP350 {ECO:0000312|HGNC:HGNC:24238}
• Organism: Homo sapiens (Human).
• Sequence Length: 3117
• Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, cilium basal body . Associated
• Protein Description: Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. [PubMed: 19052644 Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network]
• Protein Sequence: MRSSKSKEVPLPNPRNSQSKDTVQADITTSWDALSQTKAALRHIENKLEVAPTSTAVCDSVMDTKKSSTSATRKISRKDGRYLDDSWVNAPISKSTKSRKEKSRSPLRATTLESNVKKNNRVEFREPLVSYREIHGAPSNFSSSHLESKHVYCVDVNEEKTESGNWMIGSREERNIRSCDFESSQSSVINDTVVRFLNDRPAIDALQNSECLIRMGASMRTEEEMPNRTKGSENNLKLSVNNMAHDTDPKALRLTDSSPSSTSTSNSQRLDILKRRQHDVKLEKLKERIRKQWEHSEETNGRGQKLGHIDHPVMVVNVDNSVTAKVRKVATAPPAPAYKGFNPSETKIRTPDGKVWQEAEFQNMSRELYRDLALHFADDISIKEKPAEKSKEKKVVKPVRKVQKVAQLSSTECRTGSSHLISTSSWRDGQKLVKKILGPAPRMEPKEQRTASSDRGGRERTAKSGGHIGRAESDPRLDVLHRHLQRNSERSRSKSRSENNIKKLASSLPDNKQEENTALNKDFLPIEIRGILDDLQLDSTAHTAKQDTVELQNQKSSAPVHAPRSHSPVKRKPDKITANEDPPVISKRRHYDTDEVRQYIVRQQEERKRKQNEEKKAQKEATEQKNKRLQELYRKQKEAFTKVKNVPPSEPSATRRLQETYSKLLLEKTLLEEPSHQHVTQETQAKPGYQPSGESDKENKVQERPPSASSSSDMSLSEPPQPLARKDLMESTWMQPERLSPQVHHSQPQPFAGTAGSLLSHLLSLEHVGILHKDFESILPTRKNHNMASRPLTFTPQPYVTSPAAYTDALLKPSASQYKSKLDRIEALKATAASLSSRIESEAKKLAGASINYGSAWNTEYDVQQAPQEDGPWTKAVTPPVKDDNEDVFSARIQKMLGSCVSHATFDDDLPGVGNLSEFKKLPEMIRPQSAISSFRVRSPGPKPEGLLAQLCKRQTDSSSSDMQACSQDKAKISLGSSIDSVSEGPLLSEGSLSEEEGDQDGQPLLKVAEILKEKEFCPGERNSYEPIKEFQKEAEKFLPLFGHIGGTQSKGPWEELAKGSPHSVINIFTKSYQLYGKGFEDKLDRGTSTSRPLNATATPLSGVSYEDDFVSSPGTGTSTEKKSTLEPHSTLSPQEDHSNRKSAYDPSSVDVTSQHSSGAQSAASSRSSTSSKGKKGKKEKTEWLDSFTGNVQNSLLDEEKAERGSHQGKKSGTSSKLSVKDFEQTLDTDSTLEDLSGHSVSVSSDKGRSQKTPTSPLSPSSQKSLQFDVAGTSSERSKSSVMPPTITGFKPNAPLTDLNPAASRTTTENMAPIPGSKRFSPAGLHHRMAAELSYLNAIEESVRQLSDVERVRGISLAQQESVSLAQIIKAQQQRHERDLALLKLKAEQEALESQRQLEETRNKAAQVHAESLQQVVQSQREVTEVLQEATCKIAAQQSETARLTTDAARQICEMAELTRTHISDAVVASGAPLAILYDHQRQHLPDFVKQLRTRTETDRKSPSVSLSQSKEGTLDSKHQKYSASYDSYSESSGYKNHDRRSSSGSSRQESPSVPSCKENEKKLNGEKIESSIDEQVQTAADDSLRSDSVPSLPDEKDSTSIATEYSLKFDESMTEDEIEEQSFRSLLPSESHRRFNMEKRRGHHDDSDEEASPEKTTLSTAKELNMPFSGGQDSFSKFTMEMVRQYMKEEEMRAAHQSSLLRLREKALKEKTKAELAWLEHQKKHLRDKGEDDKMPPLRKKQRGLLLRLQQEKAEIKRLQEANKAARKERQLILKQQEEIEKIRQTTIKLQEKLKSAGESKLDSHSDDDTKDNKATSPGPTDLETRSPSPISISSSETSSIMQKLKKMRSRMDEKFLTKREQKLMQRRQHAEELLEWKRRLDAEEAEIRQMEKQALAAWDKELIKPKTPKKELEDQRTEQKEIASEEESPVPLYSHLNSESSIPEELGSPAVEYVPSESIGQEQPGSPDHSILTEEMICSQELESSTSPSKHSLPKSCTSVSKQESSKGSHRTGGQCHLPIKSHQHCYSWSDESLSMTQSETTSDQSDIEGRIRALKDELRKRKSVVNQLKKEQKKRQKERLKAQEASLIKQLESYDEFIKKTEAELSQDLETSPTAKPQIKTLSSASEKPKIKPLTPLHRSETAKNWKSLTESERSRGSLESIAEHVDASLSGSERSVSERSLSAYAKRVNEWDSRTEDFQTPSPVLRSSRKIREESGDSLENVPALHLLKELNATSRILDMSDGKVGESSKKSEIKEIEYTKLKKSKIEDAFSKEGKSDVLLKLVLEQGDSSEILSKKDLPLDSENVQKDLVGLAIENLHKSEEMLKERQSDQDMNHSPNIQSGKDIHEQKNTKEKDLSWSEHLFAPKEIPYSEDFEVSSFKKEISAELYKDDFEVSSLLSLRKDSQSCRDKPQPMRSSTSGATSFGSNEEISECLSEKSLSIHSNVHSDRLLELKSPTELMKSKERSDVEHEQQVTESPSLASVPTADELFDFHIGDRVLIGNVQPGILRFKGETSFAKGFWAGVELDKPEGNNNGTYDGIAYFECKEKHGIFAPPQKISHIPENFDDYVDINEDEDCYSDERYQCYNQEQNDTEGPKDREKDVSEYFYEKSLPSVNDIEASVNRSRSLKIETDNVQDISGVLEAHVHQQSSVDSQISSKENKDLISDATEKVSIAAEDDTLDNTFSEELEKQQQFTEEEDNLYAEASEKLCTPLLDLLTREKNQLEAQLKSSLNEEKKSKQQLEKISLLTDSLLKVFVKDTVNQLQQIKKTRDEKIQLSNQELLGDDQKKVTPQDLSQNVEEQSPSISGCFLSSELEDEKEEISSPDMCPRPESPVFGASGQEELAKRLAELELSREFLSALGDDQDWFDEDFGLSSSHKIQKNKAEETIVPLMAEPKRVTQQPCETLLAVPHTAEEVEILVHNAAEELWKWKELGHDLHSISIPTKLLGCASKGLDIESTSKRVYKQAVFDLTKEIFEEIFAEDPNLNQPVWMKPCRINSSYFRRVKNPNNLDEIKSFIASEVLKLFSLKKEPNHKTDWQKMMKFGRKKRDRVDHILVQELHEEEAQWVNYDEDELCVKMQLADGIFETLIKDTIDVLNQISEKQGRMLLV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MRSSKSKEVPLPN --CCCCCCCCCCCCC	35.68	28258704
19	Phosphorylation	PNPRNSQSKDTVQAD CCCCCCCCCCCEEHH	32.11	28258704
38	Ubiquitination	WDALSQTKAALRHIE HHHHHHHHHHHHHHH	24.83	21906983
47	Acetylation	ALRHIENKLEVAPTS HHHHHHHHCCCCCCC	32.98	7677769
47	Ubiquitination	ALRHIENKLEVAPTS HHHHHHHHCCCCCCC	32.98	29967540
68	Phosphorylation	VMDTKKSSTSATRKI HHCCCCCCCCCCHHH	34.95	20860994
69	Phosphorylation	MDTKKSSTSATRKIS HCCCCCCCCCCHHHC	29.49	20860994
86	Phosphorylation	DGRYLDDSWVNAPIS CCCCCCCCCCCCCCC	32.37	29978859
94	Ubiquitination	WVNAPISKSTKSRKE CCCCCCCCCCCCHHH	63.96	29967540
103	Phosphorylation	TKSRKEKSRSPLRAT CCCHHHHCCCCCCHH	38.80	25159151
105	Phosphorylation	SRKEKSRSPLRATTL CHHHHCCCCCCHHHH	35.06	30576142
110	Phosphorylation	SRSPLRATTLESNVK CCCCCCHHHHHHHCC	26.02	26074081
111	Phosphorylation	RSPLRATTLESNVKK CCCCCHHHHHHHCCC	27.78	26074081
114	Phosphorylation	LRATTLESNVKKNNR CCHHHHHHHCCCCCC	50.46	23312004
117	Ubiquitination	TTLESNVKKNNRVEF HHHHHHCCCCCCEEE	54.77	29967540
130	Phosphorylation	EFREPLVSYREIHGA EECCCCCCHHHHCCC	26.59	28555341
139	Phosphorylation	REIHGAPSNFSSSHL HHHCCCCCCCCCHHC	50.39	23917254
142	Phosphorylation	HGAPSNFSSSHLESK CCCCCCCCCHHCCCC	34.87	23917254
143	Phosphorylation	GAPSNFSSSHLESKH CCCCCCCCHHCCCCE	20.03	23186163
144	Phosphorylation	APSNFSSSHLESKHV CCCCCCCHHCCCCEE	30.78	23186163
148	Phosphorylation	FSSSHLESKHVYCVD CCCHHCCCCEEEEEE	34.13	23312004
152	Phosphorylation	HLESKHVYCVDVNEE HCCCCEEEEEECCCC	6.10	25159151
163	Phosphorylation	VNEEKTESGNWMIGS CCCCCCCCCCEECCC	42.53	28555341
178	Phosphorylation	REERNIRSCDFESSQ CCCCCCCCCCCCCCC	17.78	27732954
183	Phosphorylation	IRSCDFESSQSSVIN CCCCCCCCCCCHHCC	33.40	27732954
184	Phosphorylation	RSCDFESSQSSVIND CCCCCCCCCCHHCCH	27.21	27732954
186	Phosphorylation	CDFESSQSSVINDTV CCCCCCCCHHCCHHH	28.64	27732954
187	Phosphorylation	DFESSQSSVINDTVV CCCCCCCHHCCHHHH	21.27	27732954
209	Phosphorylation	AIDALQNSECLIRMG HHHHHCCCHHHHHCC	19.41	24719451
218	Phosphorylation	CLIRMGASMRTEEEM HHHHCCCCCCCHHHC	11.76	29083192
221	Phosphorylation	RMGASMRTEEEMPNR HCCCCCCCHHHCCCC	38.82	23186163
229	Ubiquitination	EEEMPNRTKGSENNL HHHCCCCCCCCCCCC	46.53	27667366
230	Ubiquitination	EEMPNRTKGSENNLK HHCCCCCCCCCCCCE	58.14	27667366
237	Ubiquitination	KGSENNLKLSVNNMA CCCCCCCEEEECCCC	40.62	29967540
239	Phosphorylation	SENNLKLSVNNMAHD CCCCCEEEECCCCCC	22.63	22210691
249	Ubiquitination	NMAHDTDPKALRLTD CCCCCCCCCHHHCCC	26.38	21890473
250	Ubiquitination	MAHDTDPKALRLTDS CCCCCCCCHHHCCCC	63.96	21906983
255	Phosphorylation	DPKALRLTDSSPSST CCCHHHCCCCCCCCC	27.66	20860994
257	Phosphorylation	KALRLTDSSPSSTST CHHHCCCCCCCCCCC	38.62	25627689
258	Phosphorylation	ALRLTDSSPSSTSTS HHHCCCCCCCCCCCC	31.45	25159151
260	Phosphorylation	RLTDSSPSSTSTSNS HCCCCCCCCCCCCHH	48.47	21815630
261	Phosphorylation	LTDSSPSSTSTSNSQ CCCCCCCCCCCCHHH	29.75	28450419
262	Phosphorylation	TDSSPSSTSTSNSQR CCCCCCCCCCCHHHH	40.12	29052541
263	Phosphorylation	DSSPSSTSTSNSQRL CCCCCCCCCCHHHHH	31.61	29052541
264	Phosphorylation	SSPSSTSTSNSQRLD CCCCCCCCCHHHHHH	31.83	29052541
265	Phosphorylation	SPSSTSTSNSQRLDI CCCCCCCCHHHHHHH	33.96	29052541
267	Phosphorylation	SSTSTSNSQRLDILK CCCCCCHHHHHHHHH	19.22	28450419
274	Ubiquitination	SQRLDILKRRQHDVK HHHHHHHHHHHHHHH	45.96	-
291	Ubiquitination	KLKERIRKQWEHSEE HHHHHHHHHHHCCHH	58.34	-
302	Methylation	HSEETNGRGQKLGHI CCHHHCCCCCCCCCC	46.57	-
305	Ubiquitination	ETNGRGQKLGHIDHP HHCCCCCCCCCCCCC	60.30	-
325	Ubiquitination	VDNSVTAKVRKVATA ECCCCEEEEEEEECC	32.95	-
328	Ubiquitination	SVTAKVRKVATAPPA CCEEEEEEEECCCCC	38.93	29967540
331	Phosphorylation	AKVRKVATAPPAPAY EEEEEEECCCCCCCC	42.56	-
338	Phosphorylation	TAPPAPAYKGFNPSE CCCCCCCCCCCCCCC	15.58	25884760
339	Methylation	APPAPAYKGFNPSET CCCCCCCCCCCCCCC	60.16	-
339	Ubiquitination	APPAPAYKGFNPSET CCCCCCCCCCCCCCC	60.16	29967540
347	Ubiquitination	GFNPSETKIRTPDGK CCCCCCCEEECCCCC	26.58	29967540
350	Phosphorylation	PSETKIRTPDGKVWQ CCCCEEECCCCCHHC	29.25	20860994
353	Ubiquitination	TKIRTPDGKVWQEAE CEEECCCCCHHCHHH	27.85	22817900
354	Ubiquitination	KIRTPDGKVWQEAEF EEECCCCCHHCHHHH	47.91	22817900
365	Phosphorylation	EAEFQNMSRELYRDL HHHHHHHHHHHHHHH	30.10	25850435
381	Phosphorylation	LHFADDISIKEKPAE HHHHHCCCCCCCCCC	34.30	27251275
404	Ubiquitination	KPVRKVQKVAQLSST CCHHHHHHHHHCCCC	42.39	29967540
415	Phosphorylation	LSSTECRTGSSHLIS CCCCCCCCCCCCCCC	53.74	28348404
417	Phosphorylation	STECRTGSSHLISTS CCCCCCCCCCCCCCC	17.61	28348404
418	Phosphorylation	TECRTGSSHLISTSS CCCCCCCCCCCCCCC	24.53	28348404
422	Phosphorylation	TGSSHLISTSSWRDG CCCCCCCCCCCCCCH	28.70	27251275
423	Phosphorylation	GSSHLISTSSWRDGQ CCCCCCCCCCCCCHH	21.56	27251275
424	Phosphorylation	SSHLISTSSWRDGQK CCCCCCCCCCCCHHH	22.55	27251275
425	Phosphorylation	SHLISTSSWRDGQKL CCCCCCCCCCCHHHH	26.64	27251275
435	Ubiquitination	DGQKLVKKILGPAPR CHHHHHHHHHCCCCC	35.37	29967540
473	Phosphorylation	GHIGRAESDPRLDVL CCCCCCCCCHHHHHH	52.51	23401153
488	Phosphorylation	HRHLQRNSERSRSKS HHHHHHHHHHHHHHC	36.25	29116813
493	Phosphorylation	RNSERSRSKSRSENN HHHHHHHHHCCCHHH	35.91	29116813
506	Phosphorylation	NNIKKLASSLPDNKQ HHHHHHHHCCCCCHH	42.73	28450419
507	Phosphorylation	NIKKLASSLPDNKQE HHHHHHHCCCCCHHH	38.01	28450419
511	Ubiquitination	LASSLPDNKQEENTA HHHCCCCCHHHHCCC	46.07	22817900
512	Ubiquitination	ASSLPDNKQEENTAL HHCCCCCHHHHCCCC	67.48	21906983
517	Phosphorylation	DNKQEENTALNKDFL CCHHHHCCCCCCCCC	35.48	-
521	Ubiquitination	EENTALNKDFLPIEI HHCCCCCCCCCCEEH	51.19	29967540
545	Ubiquitination	DSTAHTAKQDTVELQ CCCCCCCCHHHHHHH	50.27	29967540
555	Ubiquitination	TVELQNQKSSAPVHA HHHHHHCCCCCCCCC	54.66	29967540
556	Phosphorylation	VELQNQKSSAPVHAP HHHHHCCCCCCCCCC	23.20	-
557	Phosphorylation	ELQNQKSSAPVHAPR HHHHCCCCCCCCCCC	43.56	-
565	Phosphorylation	APVHAPRSHSPVKRK CCCCCCCCCCCCCCC	27.53	20068231
567	Phosphorylation	VHAPRSHSPVKRKPD CCCCCCCCCCCCCCC	32.41	20068231
587	Ubiquitination	EDPPVISKRRHYDTD CCCCCCCCCCCCCHH	42.18	32015554
591	Phosphorylation	VISKRRHYDTDEVRQ CCCCCCCCCHHHHHH	20.80	29496907
593	Phosphorylation	SKRRHYDTDEVRQYI CCCCCCCHHHHHHHH	27.22	-
622	O-linked_Glycosylation	KKAQKEATEQKNKRL HHHHHHHHHHHHHHH	39.79	23301498
633	Phosphorylation	NKRLQELYRKQKEAF HHHHHHHHHHHHHHH	18.27	23403867
652	O-linked_Glycosylation	NVPPSEPSATRRLQE CCCCCCCCHHHHHHH	37.92	23301498
661	Phosphorylation	TRRLQETYSKLLLEK HHHHHHHHHHHHHHH	11.76	-
663	Ubiquitination	RLQETYSKLLLEKTL HHHHHHHHHHHHHHH	32.51	32015554
668	Ubiquitination	YSKLLLEKTLLEEPS HHHHHHHHHHCCCCC	44.43	33845483
669	Phosphorylation	SKLLLEKTLLEEPSH HHHHHHHHHCCCCCH	27.48	27050516
675	Phosphorylation	KTLLEEPSHQHVTQE HHHCCCCCHHCCCCC	38.77	23186163
680	Phosphorylation	EPSHQHVTQETQAKP CCCHHCCCCCCCCCC	20.68	23186163
683	Phosphorylation	HQHVTQETQAKPGYQ HHCCCCCCCCCCCCC	24.82	23186163
685	Ubiquitination	HVTQETQAKPGYQPS CCCCCCCCCCCCCCC	27.68	21890473
686	Ubiquitination	VTQETQAKPGYQPSG CCCCCCCCCCCCCCC	29.20	22817900
689	Phosphorylation	ETQAKPGYQPSGESD CCCCCCCCCCCCCCC	26.27	21406692
692	Phosphorylation	AKPGYQPSGESDKEN CCCCCCCCCCCCCCC	39.40	23663014
695	Phosphorylation	GYQPSGESDKENKVQ CCCCCCCCCCCCCCC	58.47	29255136
707	Phosphorylation	KVQERPPSASSSSDM CCCCCCCCCCCCCCC	43.39	29255136
709	Phosphorylation	QERPPSASSSSDMSL CCCCCCCCCCCCCCC	34.78	29255136
710	Phosphorylation	ERPPSASSSSDMSLS CCCCCCCCCCCCCCC	33.31	29255136
711	Phosphorylation	RPPSASSSSDMSLSE CCCCCCCCCCCCCCC	28.06	29255136
712	Phosphorylation	PPSASSSSDMSLSEP CCCCCCCCCCCCCCC	39.00	29255136
715	Phosphorylation	ASSSSDMSLSEPPQP CCCCCCCCCCCCCCC	33.46	29255136
717	Phosphorylation	SSSDMSLSEPPQPLA CCCCCCCCCCCCCCC	40.53	29255136
726	Ubiquitination	PPQPLARKDLMESTW CCCCCCCHHHHHHCC	50.00	-
731	Phosphorylation	ARKDLMESTWMQPER CCHHHHHHCCCCHHH	17.26	22210691
732	Phosphorylation	RKDLMESTWMQPERL CHHHHHHCCCCHHHC	16.20	22210691
783	Ubiquitination	ESILPTRKNHNMASR HHHCCCCCCCCCCCC	66.10	29967540
802	Phosphorylation	TPQPYVTSPAAYTDA CCCCCCCCHHHHCCH	11.51	21857030
812	Ubiquitination	AYTDALLKPSASQYK HHCCHHHCCCHHHHH	37.46	29967540
819	Ubiquitination	KPSASQYKSKLDRIE CCCHHHHHHHHHHHH	33.21	29967540
821	Ubiquitination	SASQYKSKLDRIEAL CHHHHHHHHHHHHHH	50.70	29967540
828	Ubiquitination	KLDRIEALKATAASL HHHHHHHHHHHHHHH	2.22	21890473
829	Ubiquitination	LDRIEALKATAASLS HHHHHHHHHHHHHHH	51.22	21963094
831	Phosphorylation	RIEALKATAASLSSR HHHHHHHHHHHHHHH	22.59	20068231
834	Phosphorylation	ALKATAASLSSRIES HHHHHHHHHHHHHHH	26.73	28509920
836	Phosphorylation	KATAASLSSRIESEA HHHHHHHHHHHHHHH	18.31	20068231
837	Phosphorylation	ATAASLSSRIESEAK HHHHHHHHHHHHHHH	42.44	28509920
859	Phosphorylation	NYGSAWNTEYDVQQA CCCCCCCCCCCCCCC	25.81	-
878	Phosphorylation	GPWTKAVTPPVKDDN CCCCCCCCCCCCCCC	27.08	30266825
882	Ubiquitination	KAVTPPVKDDNEDVF CCCCCCCCCCCCCHH	66.20	29967540
890	Phosphorylation	DDNEDVFSARIQKML CCCCCHHHHHHHHHH	19.24	30266825
895	Ubiquitination	VFSARIQKMLGSCVS HHHHHHHHHHCHHHH	33.45	29967540
905	Phosphorylation	GSCVSHATFDDDLPG CHHHHCCCCCCCCCC	23.36	28348404
920	Ubiquitination	VGNLSEFKKLPEMIR CCCHHHHHCCHHHHC	49.72	29967540
921	Ubiquitination	GNLSEFKKLPEMIRP CCHHHHHCCHHHHCC	74.68	-
930	Phosphorylation	PEMIRPQSAISSFRV HHHHCCCCHHHHEEE	30.19	23403867
933	Phosphorylation	IRPQSAISSFRVRSP HCCCCHHHHEEECCC	24.12	26074081
934	Phosphorylation	RPQSAISSFRVRSPG CCCCHHHHEEECCCC	15.80	26074081
939	Phosphorylation	ISSFRVRSPGPKPEG HHHEEECCCCCCCCC	31.21	23401153
956	Phosphorylation	AQLCKRQTDSSSSDM HHHHHHCCCCCCHHH	41.71	-
958	Phosphorylation	LCKRQTDSSSSDMQA HHHHCCCCCCHHHHH	35.19	-
959	Phosphorylation	CKRQTDSSSSDMQAC HHHCCCCCCHHHHHH	36.35	-
967	Phosphorylation	SSDMQACSQDKAKIS CHHHHHHHCCCCHHC	44.42	28985074
970	Ubiquitination	MQACSQDKAKISLGS HHHHHCCCCHHCCCC	43.90	29967540
974	Phosphorylation	SQDKAKISLGSSIDS HCCCCHHCCCCCCCC	26.43	27251275
977	Phosphorylation	KAKISLGSSIDSVSE CCHHCCCCCCCCCCC	29.43	27251275
978	Phosphorylation	AKISLGSSIDSVSEG CHHCCCCCCCCCCCC	28.72	27251275
981	Phosphorylation	SLGSSIDSVSEGPLL CCCCCCCCCCCCCCC	26.35	27251275
983	Phosphorylation	GSSIDSVSEGPLLSE CCCCCCCCCCCCCCC	40.56	28102081
989	Phosphorylation	VSEGPLLSEGSLSEE CCCCCCCCCCCCCCC	47.82	28102081
992	Phosphorylation	GPLLSEGSLSEEEGD CCCCCCCCCCCCCCC	25.35	28102081
994	Phosphorylation	LLSEGSLSEEEGDQD CCCCCCCCCCCCCCC	44.66	30278072
1013	Ubiquitination	LKVAEILKEKEFCPG HHHHHHHHHCCCCCC	72.84	29967540
1015	Ubiquitination	VAEILKEKEFCPGER HHHHHHHCCCCCCCC	55.28	-
1024	Phosphorylation	FCPGERNSYEPIKEF CCCCCCCCCHHHHHH	36.77	28796482
1025	Phosphorylation	CPGERNSYEPIKEFQ CCCCCCCCHHHHHHH	29.31	28796482
1028	Ubiquitination	ERNSYEPIKEFQKEA CCCCCHHHHHHHHHH	4.45	21890473
1029	Ubiquitination	RNSYEPIKEFQKEAE CCCCHHHHHHHHHHH	64.29	27667366
1032	Ubiquitination	YEPIKEFQKEAEKFL CHHHHHHHHHHHHHH	43.71	22817900
1033	Ubiquitination	EPIKEFQKEAEKFLP HHHHHHHHHHHHHHH	65.30	22817900
1037	Ubiquitination	EFQKEAEKFLPLFGH HHHHHHHHHHHHCCC	60.28	29967540
1051	Ubiquitination	HIGGTQSKGPWEELA CCCCCCCCCHHHHHH	60.21	-
1059	Ubiquitination	GPWEELAKGSPHSVI CHHHHHHCCCCCHHH	72.97	29967540
1061	Phosphorylation	WEELAKGSPHSVINI HHHHHCCCCCHHHHH	20.80	25159151
1064	Phosphorylation	LAKGSPHSVINIFTK HHCCCCCHHHHHCCC	28.24	28450419
1072	Phosphorylation	VINIFTKSYQLYGKG HHHHCCCHHHHHCCC	18.30	-
1078	Ubiquitination	KSYQLYGKGFEDKLD CHHHHHCCCHHHCCC	47.04	29967540
1083	Ubiquitination	YGKGFEDKLDRGTST HCCCHHHCCCCCCCC	45.12	29967540
1088	Phosphorylation	EDKLDRGTSTSRPLN HHCCCCCCCCCCCCC	29.71	23312004
1089	Phosphorylation	DKLDRGTSTSRPLNA HCCCCCCCCCCCCCC	27.49	23312004
1090	Phosphorylation	KLDRGTSTSRPLNAT CCCCCCCCCCCCCCC	28.70	23312004
1091	Phosphorylation	LDRGTSTSRPLNATA CCCCCCCCCCCCCCC	31.50	23312004
1097	Phosphorylation	TSRPLNATATPLSGV CCCCCCCCCCCCCCC	29.95	23312004
1099	Phosphorylation	RPLNATATPLSGVSY CCCCCCCCCCCCCCC	22.02	23312004
1102	Phosphorylation	NATATPLSGVSYEDD CCCCCCCCCCCCCCC	38.05	23312004
1105	Phosphorylation	ATPLSGVSYEDDFVS CCCCCCCCCCCCCCC	26.74	23312004
1106	Phosphorylation	TPLSGVSYEDDFVSS CCCCCCCCCCCCCCC	22.44	23312004
1112	Phosphorylation	SYEDDFVSSPGTGTS CCCCCCCCCCCCCCC	30.70	28348404
1113	Phosphorylation	YEDDFVSSPGTGTST CCCCCCCCCCCCCCC	23.27	25159151
1116	Phosphorylation	DFVSSPGTGTSTEKK CCCCCCCCCCCCCCC	40.44	23312004
1118	Phosphorylation	VSSPGTGTSTEKKST CCCCCCCCCCCCCCC	32.11	23312004
1119	Phosphorylation	SSPGTGTSTEKKSTL CCCCCCCCCCCCCCC	35.59	23312004
1120	Phosphorylation	SPGTGTSTEKKSTLE CCCCCCCCCCCCCCC	52.22	23312004
1122	Ubiquitination	GTGTSTEKKSTLEPH CCCCCCCCCCCCCCC	52.71	-
1123	Ubiquitination	TGTSTEKKSTLEPHS CCCCCCCCCCCCCCC	42.30	29967540
1124	Phosphorylation	GTSTEKKSTLEPHST CCCCCCCCCCCCCCC	49.66	29449344
1125	Phosphorylation	TSTEKKSTLEPHSTL CCCCCCCCCCCCCCC	43.98	29449344
1130	Phosphorylation	KSTLEPHSTLSPQED CCCCCCCCCCCCCCC	41.58	23917254
1131	Phosphorylation	STLEPHSTLSPQEDH CCCCCCCCCCCCCCC	28.37	25159151
1133	Phosphorylation	LEPHSTLSPQEDHSN CCCCCCCCCCCCCCC	25.32	28985074
1139	Phosphorylation	LSPQEDHSNRKSAYD CCCCCCCCCCCCCCC	51.13	23312004
1142	Ubiquitination	QEDHSNRKSAYDPSS CCCCCCCCCCCCCCC	43.62	29967540
1162	Phosphorylation	QHSSGAQSAASSRSS CCCCCCCCCCCCCCC	25.85	30576142
1171	Phosphorylation	ASSRSSTSSKGKKGK CCCCCCCCCCCCCCC	31.81	30576142
1175	Acetylation	SSTSSKGKKGKKEKT CCCCCCCCCCCHHHC	63.19	7704325
1176	Acetylation	STSSKGKKGKKEKTE CCCCCCCCCCHHHCH	82.00	7704337
1187	Phosphorylation	EKTEWLDSFTGNVQN HHCHHHHHHCHHHHH	23.65	-
1195	Phosphorylation	FTGNVQNSLLDEEKA HCHHHHHHHCCHHHH	17.14	-
1201	Ubiquitination	NSLLDEEKAERGSHQ HHHCCHHHHHCCCCC	54.20	29967540
1219	Phosphorylation	SGTSSKLSVKDFEQT CCCCCCCCHHHHHHH	30.75	25159151
1221	Acetylation	TSSKLSVKDFEQTLD CCCCCCHHHHHHHCC	54.01	30587617
1221	Ubiquitination	TSSKLSVKDFEQTLD CCCCCCHHHHHHHCC	54.01	29967540
1229	Phosphorylation	DFEQTLDTDSTLEDL HHHHHCCCCCCHHHH	34.66	26471730
1231	Phosphorylation	EQTLDTDSTLEDLSG HHHCCCCCCHHHHCC	36.66	26471730
1232	Phosphorylation	QTLDTDSTLEDLSGH HHCCCCCCHHHHCCC	36.66	26471730
1237	Phosphorylation	DSTLEDLSGHSVSVS CCCHHHHCCCCEEEC	46.94	26471730
1240	Phosphorylation	LEDLSGHSVSVSSDK HHHHCCCCEEECCCC	21.44	26471730
1242	Phosphorylation	DLSGHSVSVSSDKGR HHCCCCEEECCCCCC	21.21	26471730
1244	Phosphorylation	SGHSVSVSSDKGRSQ CCCCEEECCCCCCCC	25.88	26471730
1245	Phosphorylation	GHSVSVSSDKGRSQK CCCEEECCCCCCCCC	40.98	26471730
1247	Ubiquitination	SVSVSSDKGRSQKTP CEEECCCCCCCCCCC	59.16	29967540
1250	Phosphorylation	VSSDKGRSQKTPTSP ECCCCCCCCCCCCCC	44.70	28450419
1253	Phosphorylation	DKGRSQKTPTSPLSP CCCCCCCCCCCCCCH	24.94	25159151
1255	Phosphorylation	GRSQKTPTSPLSPSS CCCCCCCCCCCCHHH	48.48	25159151
1256	Phosphorylation	RSQKTPTSPLSPSSQ CCCCCCCCCCCHHHH	25.66	25159151
1259	Phosphorylation	KTPTSPLSPSSQKSL CCCCCCCCHHHHCEE	26.56	25159151
1261	Phosphorylation	PTSPLSPSSQKSLQF CCCCCCHHHHCEEEE	41.86	25159151
1262	Phosphorylation	TSPLSPSSQKSLQFD CCCCCHHHHCEEEEE	45.04	22115753
1264	Acetylation	PLSPSSQKSLQFDVA CCCHHHHCEEEEEEC	55.89	7710357
1265	Phosphorylation	LSPSSQKSLQFDVAG CCHHHHCEEEEEECC	21.55	30266825
1273	Phosphorylation	LQFDVAGTSSERSKS EEEEECCCCCCCCCC	21.24	29214152
1274	Phosphorylation	QFDVAGTSSERSKSS EEEECCCCCCCCCCC	29.32	25159151
1275	Phosphorylation	FDVAGTSSERSKSSV EEECCCCCCCCCCCC	36.55	25627689
1317	Ubiquitination	NMAPIPGSKRFSPAG CCCCCCCCCCCCCCC	18.46	22817900
1318	Ubiquitination	MAPIPGSKRFSPAGL CCCCCCCCCCCCCCH	64.48	21906983
1321	Phosphorylation	IPGSKRFSPAGLHHR CCCCCCCCCCCHHHH	20.20	29214152
1334	Phosphorylation	HRMAAELSYLNAIEE HHHHHHHHHHHHHHH	21.05	27251275
1335	Phosphorylation	RMAAELSYLNAIEES HHHHHHHHHHHHHHH	19.32	27251275
1370	Ubiquitination	VSLAQIIKAQQQRHE CHHHHHHHHHHHHHH	41.60	-
1383	Ubiquitination	HERDLALLKLKAEQE HHHHHHHHHHHHHHH	5.20	22817900
1384	Ubiquitination	ERDLALLKLKAEQEA HHHHHHHHHHHHHHH	49.11	22817900
1385	Ubiquitination	RDLALLKLKAEQEAL HHHHHHHHHHHHHHH	6.83	22817900
1386	Ubiquitination	DLALLKLKAEQEALE HHHHHHHHHHHHHHH	48.57	21906983
1404	Ubiquitination	QLEETRNKAAQVHAE HHHHHHHHHHHHHHH	41.63	29967540
1412	Phosphorylation	AAQVHAESLQQVVQS HHHHHHHHHHHHHHH	32.06	28555341
1433	Ubiquitination	VLQEATCKIAAQQSE HHHHHHHHHHHHCCH	30.90	29967540
1478	Phosphorylation	GAPLAILYDHQRQHL CCCEEEHHHHHHHHH	12.79	29978859
1490	Ubiquitination	QHLPDFVKQLRTRTE HHHHHHHHHHHHCCC	43.54	29967540
1494	O-linked_Glycosylation	DFVKQLRTRTETDRK HHHHHHHHCCCCCCC	51.00	23301498
1494	Phosphorylation	DFVKQLRTRTETDRK HHHHHHHHCCCCCCC	51.00	23312004
1496	Phosphorylation	VKQLRTRTETDRKSP HHHHHHCCCCCCCCC	42.49	23312004
1498	Phosphorylation	QLRTRTETDRKSPSV HHHHCCCCCCCCCCC	40.26	23312004
1502	Phosphorylation	RTETDRKSPSVSLSQ CCCCCCCCCCCCHHH	24.25	25159151
1504	Phosphorylation	ETDRKSPSVSLSQSK CCCCCCCCCCHHHCC	31.28	25850435
1506	Phosphorylation	DRKSPSVSLSQSKEG CCCCCCCCHHHCCCC	27.00	27732954
1508	Phosphorylation	KSPSVSLSQSKEGTL CCCCCCHHHCCCCCC	25.54	23312004
1510	Phosphorylation	PSVSLSQSKEGTLDS CCCCHHHCCCCCCCC	29.33	25627689
1511	Ubiquitination	SVSLSQSKEGTLDSK CCCHHHCCCCCCCCC	53.15	29967540
1528	Phosphorylation	KYSASYDSYSESSGY HCCCCCCCCCCCCCC	23.48	24247654
1529	Phosphorylation	YSASYDSYSESSGYK CCCCCCCCCCCCCCC	17.35	27251275
1530	Phosphorylation	SASYDSYSESSGYKN CCCCCCCCCCCCCCC	34.65	24247654
1536	Ubiquitination	YSESSGYKNHDRRSS CCCCCCCCCCCCCCC	51.86	29967540
1542	Phosphorylation	YKNHDRRSSSGSSRQ CCCCCCCCCCCCCCC	29.74	23882029
1543	Phosphorylation	KNHDRRSSSGSSRQE CCCCCCCCCCCCCCC	36.59	23882029
1544	Phosphorylation	NHDRRSSSGSSRQES CCCCCCCCCCCCCCC	43.89	23882029
1546	Phosphorylation	DRRSSSGSSRQESPS CCCCCCCCCCCCCCC	25.05	23882029
1547	Phosphorylation	RRSSSGSSRQESPSV CCCCCCCCCCCCCCC	41.32	23882029
1551	Phosphorylation	SGSSRQESPSVPSCK CCCCCCCCCCCCCHH	17.71	28985074
1592	Phosphorylation	LRSDSVPSLPDEKDS CCCCCCCCCCCCCCC	50.83	28348404
1607	Phosphorylation	TSIATEYSLKFDESM CCCHHHHEEECCCCC	20.89	24719451
1613	Phosphorylation	YSLKFDESMTEDEIE HEEECCCCCCHHHHH	32.61	25159151
1615	Phosphorylation	LKFDESMTEDEIEEQ EECCCCCCHHHHHHH	49.95	26074081
1630	Phosphorylation	SFRSLLPSESHRRFN HHHHHCCCHHHHHCC	52.26	23312004
1632	Phosphorylation	RSLLPSESHRRFNME HHHCCCHHHHHCCCC	26.99	23312004
1648	Phosphorylation	RRGHHDDSDEEASPE HCCCCCCCCCCCCCC	53.64	29255136
1653	Phosphorylation	DDSDEEASPEKTTLS CCCCCCCCCCCCCHH	36.55	23927012
1663	Ubiquitination	KTTLSTAKELNMPFS CCCHHHHHHHCCCCC	63.92	29967540
1670	Phosphorylation	KELNMPFSGGQDSFS HHHCCCCCCCCCHHH	35.82	20860994
1675	Phosphorylation	PFSGGQDSFSKFTME CCCCCCCHHHHHHHH	24.43	26471730
1677	Phosphorylation	SGGQDSFSKFTMEMV CCCCCHHHHHHHHHH	30.71	27251275
1700	Phosphorylation	MRAAHQSSLLRLREK HHHHHHHHHHHHHHH	25.50	24719451
1735	Methylation	RDKGEDDKMPPLRKK HHCCCCCCCCCHHHH	66.67	-
1797	Phosphorylation	KLQEKLKSAGESKLD HHHHHHHHCCCCCCC	52.52	25072903
1801	Phosphorylation	KLKSAGESKLDSHSD HHHHCCCCCCCCCCC	37.29	30576142
1805	Phosphorylation	AGESKLDSHSDDDTK CCCCCCCCCCCCCCC	35.01	28176443
1807	Phosphorylation	ESKLDSHSDDDTKDN CCCCCCCCCCCCCCC	46.84	28176443
1811	Phosphorylation	DSHSDDDTKDNKATS CCCCCCCCCCCCCCC	47.49	30576142
1817	Phosphorylation	DTKDNKATSPGPTDL CCCCCCCCCCCCCCC	36.74	23401153
1818	Phosphorylation	TKDNKATSPGPTDLE CCCCCCCCCCCCCCC	32.49	29255136
1822	Phosphorylation	KATSPGPTDLETRSP CCCCCCCCCCCCCCC	60.16	23090842
1826	Phosphorylation	PGPTDLETRSPSPIS CCCCCCCCCCCCCCC	43.68	29255136
1828	Phosphorylation	PTDLETRSPSPISIS CCCCCCCCCCCCCCC	36.83	22617229
1830	Phosphorylation	DLETRSPSPISISSS CCCCCCCCCCCCCCH	35.79	25159151
1833	Phosphorylation	TRSPSPISISSSETS CCCCCCCCCCCHHHH	21.57	30108239
1835	Phosphorylation	SPSPISISSSETSSI CCCCCCCCCHHHHHH	22.48	23090842
1836	Phosphorylation	PSPISISSSETSSIM CCCCCCCCHHHHHHH	30.44	23090842
1837	Phosphorylation	SPISISSSETSSIMQ CCCCCCCHHHHHHHH	37.80	23090842
1839	Phosphorylation	ISISSSETSSIMQKL CCCCCHHHHHHHHHH	29.71	23090842
1840	Phosphorylation	SISSSETSSIMQKLK CCCCHHHHHHHHHHH	17.51	23090842
1841	Phosphorylation	ISSSETSSIMQKLKK CCCHHHHHHHHHHHH	29.51	23090842
1906	Ubiquitination	AWDKELIKPKTPKKE HHHHHHHCCCCCHHH	53.76	32015554
1909	O-linked_Glycosylation	KELIKPKTPKKELED HHHHCCCCCHHHHHH	49.20	23301498
1909	Phosphorylation	KELIKPKTPKKELED HHHHCCCCCHHHHHH	49.20	28122231
1926	Phosphorylation	TEQKEIASEEESPVP HHHHHHCCCCCCCCC	51.72	26074081
1936	Phosphorylation	ESPVPLYSHLNSESS CCCCCCHHHCCCCCC	29.22	-
1955	Phosphorylation	LGSPAVEYVPSESIG HCCCCEEECCHHHCC	15.86	26074081
1958	Phosphorylation	PAVEYVPSESIGQEQ CCEEECCHHHCCCCC	33.65	26074081
1960	Phosphorylation	VEYVPSESIGQEQPG EEECCHHHCCCCCCC	36.03	26074081
1968	Phosphorylation	IGQEQPGSPDHSILT CCCCCCCCCCCCHHC	33.56	26074081
1972	Phosphorylation	QPGSPDHSILTEEMI CCCCCCCCHHCHHHH	27.03	26074081
1975	Phosphorylation	SPDHSILTEEMICSQ CCCCCHHCHHHHHCH	28.38	26074081
1986	Phosphorylation	ICSQELESSTSPSKH HHCHHHHCCCCCCCC	52.09	26074081
1987	Phosphorylation	CSQELESSTSPSKHS HCHHHHCCCCCCCCC	24.43	26074081
1988	Phosphorylation	SQELESSTSPSKHSL CHHHHCCCCCCCCCC	54.67	26074081
1989	Phosphorylation	QELESSTSPSKHSLP HHHHCCCCCCCCCCC	29.17	26074081
1991	Phosphorylation	LESSTSPSKHSLPKS HHCCCCCCCCCCCCC	42.65	26074081
1994	Phosphorylation	STSPSKHSLPKSCTS CCCCCCCCCCCCCCC	50.53	26074081
1998	Phosphorylation	SKHSLPKSCTSVSKQ CCCCCCCCCCCCCCC	22.23	-
2000	Phosphorylation	HSLPKSCTSVSKQES CCCCCCCCCCCCCCC	38.97	-
2003	Phosphorylation	PKSCTSVSKQESSKG CCCCCCCCCCCCCCC	28.52	-
2058	Ubiquitination	EGRIRALKDELRKRK HHHHHHHHHHHHHHH	48.44	29967540
2065	Ubiquitination	KDELRKRKSVVNQLK HHHHHHHHHHHHHHH	51.11	29967540
2076	Methylation	NQLKKEQKKRQKERL HHHHHHHHHHHHHHH	51.52	-
2089	Phosphorylation	RLKAQEASLIKQLES HHHHHHHHHHHHHHC	29.85	24719451
2092	Ubiquitination	AQEASLIKQLESYDE HHHHHHHHHHHCHHH	54.87	29967540
2104	Phosphorylation	YDEFIKKTEAELSQD HHHHHHHHHHHHHHC	35.11	20860994
2109	Phosphorylation	KKTEAELSQDLETSP HHHHHHHHHCCCCCC	17.10	30108239
2114	Phosphorylation	ELSQDLETSPTAKPQ HHHHCCCCCCCCCHH	47.50	25159151
2115	Phosphorylation	LSQDLETSPTAKPQI HHHCCCCCCCCCHHH	15.75	23401153
2117	Phosphorylation	QDLETSPTAKPQIKT HCCCCCCCCCHHHHC	47.26	25159151
2126	Phosphorylation	KPQIKTLSSASEKPK CHHHHCCCCCCCCCC	29.14	-
2127	Phosphorylation	PQIKTLSSASEKPKI HHHHCCCCCCCCCCC	38.64	-
2129	Phosphorylation	IKTLSSASEKPKIKP HHCCCCCCCCCCCCC	48.37	-
2138	Phosphorylation	KPKIKPLTPLHRSET CCCCCCCCCCCCCCC	32.12	23312004
2151	Phosphorylation	ETAKNWKSLTESERS CCCCCHHHCCHHHHH	31.94	-
2158	Phosphorylation	SLTESERSRGSLESI HCCHHHHHCCCHHHH	36.62	21712546
2161	Phosphorylation	ESERSRGSLESIAEH HHHHHCCCHHHHHHH	28.05	21712546
2164	Phosphorylation	RSRGSLESIAEHVDA HHCCCHHHHHHHHHH	32.18	28348404
2172	Phosphorylation	IAEHVDASLSGSERS HHHHHHHHCCCCCCC	20.71	21712546
2174	Phosphorylation	EHVDASLSGSERSVS HHHHHHCCCCCCCCC	37.47	25159151
2176	Phosphorylation	VDASLSGSERSVSER HHHHCCCCCCCCCHH	26.85	21712546
2186	Phosphorylation	SVSERSLSAYAKRVN CCCHHHHHHHHHHHH	22.08	28555341
2188	Phosphorylation	SERSLSAYAKRVNEW CHHHHHHHHHHHHHH	14.85	-
2199	Phosphorylation	VNEWDSRTEDFQTPS HHHHHHCCCCCCCCC	43.81	28270605
2204	Phosphorylation	SRTEDFQTPSPVLRS HCCCCCCCCCHHHHC	26.23	29255136
2206	Phosphorylation	TEDFQTPSPVLRSSR CCCCCCCCHHHHCCH	30.91	29255136
2211	Phosphorylation	TPSPVLRSSRKIREE CCCHHHHCCHHHHHH	30.27	28270605
2212	Phosphorylation	PSPVLRSSRKIREES CCHHHHCCHHHHHHH	31.03	28270605
2222	Phosphorylation	IREESGDSLENVPAL HHHHHCCCCCCCCHH	40.90	25159151
2233	Ubiquitination	VPALHLLKELNATSR CCHHHHHHHHCCCCC	67.52	29967540
2238	Phosphorylation	LLKELNATSRILDMS HHHHHCCCCCEEECC	19.91	20068231
2239	Phosphorylation	LKELNATSRILDMSD HHHHCCCCCEEECCC	18.21	20068231
2245	Phosphorylation	TSRILDMSDGKVGES CCCEEECCCCCCCCC	42.76	21815630
2252	Phosphorylation	SDGKVGESSKKSEIK CCCCCCCCCCHHHCC	41.34	24850871
2253	Phosphorylation	DGKVGESSKKSEIKE CCCCCCCCCHHHCCE	39.54	24850871
2263	Phosphorylation	SEIKEIEYTKLKKSK HHCCEEEHHHCCHHH	18.16	26074081
2264	Phosphorylation	EIKEIEYTKLKKSKI HCCEEEHHHCCHHHH	19.67	26074081
2276	O-linked_Glycosylation	SKIEDAFSKEGKSDV HHHHHHHCCCCCHHH	31.36	23301498
2312	Ubiquitination	LDSENVQKDLVGLAI CCCHHHHHHHHHHHH	49.07	29967540
2341	Phosphorylation	SDQDMNHSPNIQSGK CCCCCCCCCCCCCCH	18.03	25849741
2362	Phosphorylation	NTKEKDLSWSEHLFA CCCCCCCCHHHHCCC	38.39	25159151
2364	Phosphorylation	KEKDLSWSEHLFAPK CCCCCCHHHHCCCCC	16.26	22115753
2383	Phosphorylation	SEDFEVSSFKKEISA CCCCCHHHCHHHHCH	46.38	30576142
2385	Ubiquitination	DFEVSSFKKEISAEL CCCHHHCHHHHCHHH	51.98	29967540
2393	Phosphorylation	KEISAELYKDDFEVS HHHCHHHHCCCCHHH	12.13	25159151
2409	Phosphorylation	LLSLRKDSQSCRDKP HHHHHCCCHHHCCCC	27.33	-
2421	Phosphorylation	DKPQPMRSSTSGATS CCCCCCCCCCCCCCC	31.54	27732954
2422	Phosphorylation	KPQPMRSSTSGATSF CCCCCCCCCCCCCCC	19.07	27732954
2423	Phosphorylation	PQPMRSSTSGATSFG CCCCCCCCCCCCCCC	32.21	27732954
2424	Phosphorylation	QPMRSSTSGATSFGS CCCCCCCCCCCCCCC	28.51	27732954
2427	Phosphorylation	RSSTSGATSFGSNEE CCCCCCCCCCCCHHH	28.28	27732954
2428	Phosphorylation	SSTSGATSFGSNEEI CCCCCCCCCCCHHHH	27.38	28450419
2431	Phosphorylation	SGATSFGSNEEISEC CCCCCCCCHHHHHHH	38.77	28450419
2436	Phosphorylation	FGSNEEISECLSEKS CCCHHHHHHHHHCCC	26.07	27732954
2440	Phosphorylation	EEISECLSEKSLSIH HHHHHHHHCCCCCEE	55.42	27732954
2443	Phosphorylation	SECLSEKSLSIHSNV HHHHHCCCCCEECCC	24.25	23898821
2445	Phosphorylation	CLSEKSLSIHSNVHS HHHCCCCCEECCCCH	25.91	25159151
2448	Phosphorylation	EKSLSIHSNVHSDRL CCCCCEECCCCHHHH	38.59	-
2452	Phosphorylation	SIHSNVHSDRLLELK CEECCCCHHHHHHCC	21.83	-
2460	Phosphorylation	DRLLELKSPTELMKS HHHHHCCCHHHHHHC	50.07	29255136
2462	Phosphorylation	LLELKSPTELMKSKE HHHCCCHHHHHHCCC	49.17	30266825
2467	Phosphorylation	SPTELMKSKERSDVE CHHHHHHCCCCCCCC	26.28	20068231
2480	Phosphorylation	VEHEQQVTESPSLAS CCHHHHHCCCCCCCC	26.80	26471730
2482	Phosphorylation	HEQQVTESPSLASVP HHHHHCCCCCCCCCC	15.49	25627689
2484	Phosphorylation	QQVTESPSLASVPTA HHHCCCCCCCCCCCH	45.94	25627689
2487	Phosphorylation	TESPSLASVPTADEL CCCCCCCCCCCHHHH	33.64	25627689
2516	Ubiquitination	QPGILRFKGETSFAK CCCEEEECCCCCCCC	49.78	29967540
2519	O-linked_Glycosylation	ILRFKGETSFAKGFW EEEECCCCCCCCCEE	37.50	23301498
2520	Phosphorylation	LRFKGETSFAKGFWA EEECCCCCCCCCEEE	20.92	24719451
2573	Phosphorylation	IPENFDDYVDINEDE CCCCCCCCCCCCCCC	11.23	22817900
2583	Phosphorylation	INEDEDCYSDERYQC CCCCCCCCCCHHHHC	31.32	27732954
2584	Phosphorylation	NEDEDCYSDERYQCY CCCCCCCCCHHHHCC	39.05	27732954
2588	Phosphorylation	DCYSDERYQCYNQEQ CCCCCHHHHCCCCCC	10.82	-
2591	Phosphorylation	SDERYQCYNQEQNDT CCHHHHCCCCCCCCC	12.35	-
2609	Phosphorylation	KDREKDVSEYFYEKS CCHHCHHHHHHHHHC	36.39	29978859
2611	Phosphorylation	REKDVSEYFYEKSLP HHCHHHHHHHHHCCC	12.17	28796482
2613	Phosphorylation	KDVSEYFYEKSLPSV CHHHHHHHHHCCCCH	22.88	28796482
2616	Phosphorylation	SEYFYEKSLPSVNDI HHHHHHHCCCCHHHH	33.31	27732954
2619	Phosphorylation	FYEKSLPSVNDIEAS HHHHCCCCHHHHHHH	38.55	27732954
2626	Phosphorylation	SVNDIEASVNRSRSL CHHHHHHHCHHCCCC	13.72	30576142
2630	Phosphorylation	IEASVNRSRSLKIET HHHHCHHCCCCEEEE	22.48	30576142
2671	Phosphorylation	KENKDLISDATEKVS HHHHHHCCCCHHHHH	28.61	25159151
2678	Phosphorylation	SDATEKVSIAAEDDT CCCHHHHHHHCCCCC	19.99	23186163
2685	Phosphorylation	SIAAEDDTLDNTFSE HHHCCCCCCCCCCHH	48.62	21712546
2689	Phosphorylation	EDDTLDNTFSEELEK CCCCCCCCCHHHHHH	28.36	25159151
2691	Phosphorylation	DTLDNTFSEELEKQQ CCCCCCCHHHHHHHH	28.29	25159151
2701	Phosphorylation	LEKQQQFTEEEDNLY HHHHHCCCHHHHHHH	37.84	27642862
2708	Phosphorylation	TEEEDNLYAEASEKL CHHHHHHHHHHHHHH	14.51	28796482
2712	Phosphorylation	DNLYAEASEKLCTPL HHHHHHHHHHHHHHH	27.11	28796482
2717	Phosphorylation	EASEKLCTPLLDLLT HHHHHHHHHHHHHHH	27.66	21815630
2736	O-linked_Glycosylation	QLEAQLKSSLNEEKK HHHHHHHHHCCHHHH	48.96	23301498
2737	O-linked_Glycosylation	LEAQLKSSLNEEKKS HHHHHHHHCCHHHHH	33.36	23301498
2757	Phosphorylation	KISLLTDSLLKVFVK HHHHHHHHHHHHHHH	30.30	24719451
2780	Ubiquitination	IKKTRDEKIQLSNQE HHHHHHHHCCCCHHH	39.79	29967540
2829	Phosphorylation	EDEKEEISSPDMCPR HHHHHHCCCCCCCCC	38.81	25159151
2830	Phosphorylation	DEKEEISSPDMCPRP HHHHHCCCCCCCCCC	30.49	25159151
2839	Phosphorylation	DMCPRPESPVFGASG CCCCCCCCCCCCCCC	29.10	29255136
2845	Phosphorylation	ESPVFGASGQEELAK CCCCCCCCCHHHHHH	41.19	26074081
2860	Phosphorylation	RLAELELSREFLSAL HHHHHHHHHHHHHHH	22.01	21815630
2894	Phosphorylation	QKNKAEETIVPLMAE CCCCCCCCCHHHHCC	20.84	23532336
2904	Methylation	PLMAEPKRVTQQPCE HHHCCCCCCCCCCCC	47.64	-
2938	Ubiquitination	AEELWKWKELGHDLH HHHHHHHHHHCCCHH	39.06	29967540
2946	Phosphorylation	ELGHDLHSISIPTKL HHCCCHHHCCCCHHH	25.90	26074081
2948	Phosphorylation	GHDLHSISIPTKLLG CCCHHHCCCCHHHHH	26.06	26074081
2951	Phosphorylation	LHSISIPTKLLGCAS HHHCCCCHHHHHHHH	32.43	26074081
2952	Ubiquitination	HSISIPTKLLGCASK HHCCCCHHHHHHHHC	36.04	29967540
2958	Phosphorylation	TKLLGCASKGLDIES HHHHHHHHCCCCCHH	31.19	20068231
2959	Ubiquitination	KLLGCASKGLDIEST HHHHHHHCCCCCHHC	44.99	29967540
2965	Phosphorylation	SKGLDIESTSKRVYK HCCCCCHHCCHHHHH	38.01	20068231
2966	Phosphorylation	KGLDIESTSKRVYKQ CCCCCHHCCHHHHHH	26.02	20068231
2967	Phosphorylation	GLDIESTSKRVYKQA CCCCHHCCHHHHHHH	27.95	20068231
2968	Ubiquitination	LDIESTSKRVYKQAV CCCHHCCHHHHHHHH	46.07	29967540
3013	Ubiquitination	SSYFRRVKNPNNLDE HHHHHCCCCCCCHHH	65.95	29967540
3022	Ubiquitination	PNNLDEIKSFIASEV CCCHHHHHHHHHHHH	36.95	29967540
3034	Phosphorylation	SEVLKLFSLKKEPNH HHHHHHHCCCCCCCC	50.11	24719451
3036	Ubiquitination	VLKLFSLKKEPNHKT HHHHHCCCCCCCCCC	54.62	27667366
3037	Ubiquitination	LKLFSLKKEPNHKTD HHHHCCCCCCCCCCH	81.39	29967540
3043	Phosphorylation	KKEPNHKTDWQKMMK CCCCCCCCHHHHHHH	34.61	24719451
3055	Acetylation	MMKFGRKKRDRVDHI HHHHCCHHHHCCCEE	59.16	7705975
3067	Ubiquitination	DHILVQELHEEEAQW CEEEEHHHCHHHCCC	3.26	27667366
3076	Ubiquitination	EEEAQWVNYDEDELC HHHCCCCCCCHHHHH	35.26	27667366
3085	Ubiquitination	DEDELCVKMQLADGI CHHHHHHHHHHHCCH	21.67	27667366
3086	Ubiquitination	EDELCVKMQLADGIF HHHHHHHHHHHCCHH	1.65	27667366
3108	Ubiquitination	IDVLNQISEKQGRML HHHHHHHHHHCCCCC	29.04	27667366
3110	Acetylation	VLNQISEKQGRMLLV HHHHHHHHCCCCCCC	51.79	28643663
3110	Ubiquitination	VLNQISEKQGRMLLV HHHHHHHHCCCCCCC	51.79	29967540

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CE350_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CE350_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CE350_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CYLD_HUMAN	CYLD	physical	25134987
PPARA_HUMAN	PPARA	physical	15615782
PPARG_HUMAN	PPARG	physical	15615782
PPARD_HUMAN	PPARD	physical	15615782
NR1H3_HUMAN	NR1H3	physical	15615782

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-86, AND MASSSPECTROMETRY.
PubMed: 19690332

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1256; SER-1259; SER-2115AND THR-2462, AND MASS SPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-878; THR-1253; SER-1256;SER-1259; THR-2204; SER-2206 AND SER-2460, AND MASS SPECTROMETRY.
PubMed: 18669648

"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis.";
Wang B., Malik R., Nigg E.A., Korner R.;
Anal. Chem. 80:9526-9533(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-258; SER-1502; THR-1817AND SER-1818, AND MASS SPECTROMETRY.
PubMed: 19007248

"Phosphoproteome analysis of the human mitotic spindle.";
Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.;
Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1818, SUBCELLULARLOCATION, AND MASS SPECTROMETRY.
PubMed: 16565220

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2460, AND MASSSPECTROMETRY.
PubMed: 17081983