IFT22_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IFT22_HUMAN
• UniProt AC: Q9H7X7
• Protein Name: Intraflagellar transport protein 22 homolog
• Gene Name: IFT22
• Organism: Homo sapiens (Human).
• Sequence Length: 185
• Subcellular Localization: Cell projection, cilium.
• Protein Description: Small GTPase-like component of the intraflagellar transport (IFT) complex B..
• Protein Sequence: MLKAKILFVGPCESGKTVLANFLTESSDITEYSPTQGVRILEFENPHVTSNNKGTGCEFELWDCGGDAKFESCWPALMKDAHGVVIVFNADIPSHRKEMEMWYSCFVQQPSLQDTQCMLIAHHKPGSGDDKGSLSLSPPLNKLKLVHSNLEDDPEEIRMEFIKYLKSIINSMSESRDREEMSIMT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
33	Phosphorylation	SSDITEYSPTQGVRI CCCCCCCCCCCCEEE		27251275
53	Ubiquitination	PHVTSNNKGTGCEFE CCCCCCCCCCCCEEE		-
72	Phosphorylation	GGDAKFESCWPALMK CCCCCHHHHHHHHHC		27251275
133	Phosphorylation	GSGDDKGSLSLSPPL CCCCCCCCCCCCCCC		29396449
135	Phosphorylation	GDDKGSLSLSPPLNK CCCCCCCCCCCCCCC		30266825
137	Phosphorylation	DKGSLSLSPPLNKLK CCCCCCCCCCCCCEE		30266825
144	Ubiquitination	SPPLNKLKLVHSNLE CCCCCCEEEHHHCCC		-
163	Ubiquitination	EIRMEFIKYLKSIIN HHHHHHHHHHHHHHH		-
164	Phosphorylation	IRMEFIKYLKSIINS HHHHHHHHHHHHHHH		29083192
166	Ubiquitination	MEFIKYLKSIINSMS HHHHHHHHHHHHHHH		-
167	Phosphorylation	EFIKYLKSIINSMSE HHHHHHHHHHHHHHC		29083192
171	Phosphorylation	YLKSIINSMSESRDR HHHHHHHHHHCCCCH		29083192
173	Phosphorylation	KSIINSMSESRDREE HHHHHHHHCCCCHHH		29083192
175	Phosphorylation	IINSMSESRDREEMS HHHHHHCCCCHHHHC		29083192
182	Phosphorylation	SRDREEMSIMT---- CCCHHHHCCCC----		-
185	Phosphorylation	REEMSIMT------- HHHHCCCC-------		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IFT22_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IFT22_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IFT22_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RBM33_HUMAN	RBM33	physical	22939629
IFT74_HUMAN	IFT74	physical	27173435
IFT52_HUMAN	IFT52	physical	27173435
IF172_HUMAN	IFT172	physical	27173435
IFT46_HUMAN	IFT46	physical	27173435
IFT57_HUMAN	IFT57	physical	27173435

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.