| UniProt ID | CP131_HUMAN | |
|---|---|---|
| UniProt AC | Q9UPN4 | |
| Protein Name | Centrosomal protein of 131 kDa | |
| Gene Name | CEP131 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1083 | |
| Subcellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Cytoplasm, cytoskeleton, cilium basal body. Cytoplasmic vesicle, secretory vesicle, acrosome . | |
| Protein Description | Component of centriolar satellites contributing to the building of a complex and dynamic network required to regulate cilia/flagellum formation. [PubMed: 17954613] | |
| Protein Sequence | MKGTRAIGSVPERSPAGVDLSLTGLPPPVSRRPGSAATTKPIVRSVSVVTGSEQKRKVLEATGPGGSQAINNLRRSNSTTQVSQPRSGSPRPTEPTDFLMLFEGSPSGKKRPASLSTAPSEKGATWNVLDDQPRGFTLPSNARSSSALDSPAGPRRKECTVALAPNFTANNRSNKGAVGNCVTTMVHNRYTPSERAPPLKSSNQTAPSLNNIIKAATCEGSESSGFGKLPKNVSSATHSARNNTGGSTGLPRRKEVTEEEAERFIHQVNQATVTIQRWYRHQVQRRGAGAARLEHLLQAKREEQRQRSGEGTLLDLHQQKEAARRKAREEKARQARRAAIQELQQKRALRAQKASTAERGPPENPRETRVPGMRQPAQELSPTPGGTAHQALKANNTGGGLPAAGPGDRCLPTSDSSPEPQQPPEDRTQDVLAQDAAGDNLEMMAPSRGSAKSRGPLEELLHTLQLLEKEPDVLPRPRTHHRGRYAWASEVTTEDDASSLTADNLEKFGKLSAFPEPPEDGTLLSEAKLQSIMSFLDEMEKSGQDQLDSQQEGWVPEAGPGPLELGSEVSTSVMRLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKWISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTRKEEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEEVHRRVKTALARKEEAVSSLRTQHEAAVKRADHLEELLEQHRRPTPSTK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 9 | Phosphorylation | KGTRAIGSVPERSPA CCCCCCCCCCCCCCC | 27251275 | ||
| 14 | Phosphorylation | IGSVPERSPAGVDLS CCCCCCCCCCCCCCH | 30266825 | ||
| 21 | Phosphorylation | SPAGVDLSLTGLPPP CCCCCCCHHCCCCCC | 30266825 | ||
| 23 | Phosphorylation | AGVDLSLTGLPPPVS CCCCCHHCCCCCCCC | 27251275 | ||
| 30 | Phosphorylation | TGLPPPVSRRPGSAA CCCCCCCCCCCCCCC | 27251275 | ||
| 35 | Phosphorylation | PVSRRPGSAATTKPI CCCCCCCCCCCCCCC | 30266825 | ||
| 38 | Phosphorylation | RRPGSAATTKPIVRS CCCCCCCCCCCCEEE | 29255136 | ||
| 39 | Phosphorylation | RPGSAATTKPIVRSV CCCCCCCCCCCEEEE | 23312004 | ||
| 40 | Ubiquitination | PGSAATTKPIVRSVS CCCCCCCCCCEEEEE | - | ||
| 40 (in isoform 2) | Ubiquitination | - | - | ||
| 45 | Phosphorylation | TTKPIVRSVSVVTGS CCCCCEEEEEEECCC | 30266825 | ||
| 47 | Phosphorylation | KPIVRSVSVVTGSEQ CCCEEEEEEECCCHH | 25159151 | ||
| 50 | Phosphorylation | VRSVSVVTGSEQKRK EEEEEEECCCHHHHH | 23403867 | ||
| 52 | Phosphorylation | SVSVVTGSEQKRKVL EEEEECCCHHHHHHH | 25159151 | ||
| 57 | Ubiquitination | TGSEQKRKVLEATGP CCCHHHHHHHHHCCC | 21890473 | ||
| 57 | Ubiquitination | TGSEQKRKVLEATGP CCCHHHHHHHHHCCC | 21890473 | ||
| 57 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 57 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 62 | Phosphorylation | KRKVLEATGPGGSQA HHHHHHHCCCCHHHH | 20068231 | ||
| 67 | Phosphorylation | EATGPGGSQAINNLR HHCCCCHHHHHHHHH | 20068231 | ||
| 76 | Phosphorylation | AINNLRRSNSTTQVS HHHHHHHCCCCCCCC | 25159151 | ||
| 78 | Phosphorylation | NNLRRSNSTTQVSQP HHHHHCCCCCCCCCC | 25159151 | ||
| 79 | Phosphorylation | NLRRSNSTTQVSQPR HHHHCCCCCCCCCCC | 21955146 | ||
| 80 | Phosphorylation | LRRSNSTTQVSQPRS HHHCCCCCCCCCCCC | 26329039 | ||
| 83 | Phosphorylation | SNSTTQVSQPRSGSP CCCCCCCCCCCCCCC | 22210691 | ||
| 87 | Phosphorylation | TQVSQPRSGSPRPTE CCCCCCCCCCCCCCC | 22167270 | ||
| 89 | Phosphorylation | VSQPRSGSPRPTEPT CCCCCCCCCCCCCCC | 22167270 | ||
| 93 | Phosphorylation | RSGSPRPTEPTDFLM CCCCCCCCCCCCEEE | 22167270 | ||
| 96 | Phosphorylation | SPRPTEPTDFLMLFE CCCCCCCCCEEEEEE | 22167270 | ||
| 105 | Phosphorylation | FLMLFEGSPSGKKRP EEEEEECCCCCCCCC | 25159151 | ||
| 107 | Phosphorylation | MLFEGSPSGKKRPAS EEEECCCCCCCCCCC | 30278072 | ||
| 110 | Ubiquitination | EGSPSGKKRPASLST ECCCCCCCCCCCCCC | - | ||
| 110 (in isoform 2) | Ubiquitination | - | - | ||
| 114 | Phosphorylation | SGKKRPASLSTAPSE CCCCCCCCCCCCCCC | 30266825 | ||
| 116 | Phosphorylation | KKRPASLSTAPSEKG CCCCCCCCCCCCCCC | 30266825 | ||
| 117 | Phosphorylation | KRPASLSTAPSEKGA CCCCCCCCCCCCCCC | 30266825 | ||
| 120 | Phosphorylation | ASLSTAPSEKGATWN CCCCCCCCCCCCCCC | 30266825 | ||
| 122 | Ubiquitination | LSTAPSEKGATWNVL CCCCCCCCCCCCCCC | 21890473 | ||
| 122 | Ubiquitination | LSTAPSEKGATWNVL CCCCCCCCCCCCCCC | 21890473 | ||
| 122 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 122 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 125 | Phosphorylation | APSEKGATWNVLDDQ CCCCCCCCCCCCCCC | 23312004 | ||
| 137 | Phosphorylation | DDQPRGFTLPSNARS CCCCCCCCCCCCCCC | 23917254 | ||
| 140 | Phosphorylation | PRGFTLPSNARSSSA CCCCCCCCCCCCCCC | 28555341 | ||
| 144 | Phosphorylation | TLPSNARSSSALDSP CCCCCCCCCCCCCCC | 30266825 | ||
| 145 | Phosphorylation | LPSNARSSSALDSPA CCCCCCCCCCCCCCC | 30266825 | ||
| 146 | Phosphorylation | PSNARSSSALDSPAG CCCCCCCCCCCCCCC | 30266825 | ||
| 150 | Phosphorylation | RSSSALDSPAGPRRK CCCCCCCCCCCCCCC | 19664994 | ||
| 157 | Ubiquitination | SPAGPRRKECTVALA CCCCCCCCCCEEEEC | 21890473 | ||
| 157 | Acetylation | SPAGPRRKECTVALA CCCCCCCCCCEEEEC | 18586887 | ||
| 157 | Ubiquitination | SPAGPRRKECTVALA CCCCCCCCCCEEEEC | 21890473 | ||
| 157 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 157 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 175 | Ubiquitination | TANNRSNKGAVGNCV CCCCCCCCCCCCCHH | 21890473 | ||
| 175 | Ubiquitination | TANNRSNKGAVGNCV CCCCCCCCCCCCCHH | 21890473 | ||
| 175 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 175 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 190 | Phosphorylation | TTMVHNRYTPSERAP HHHHHCCCCCCCCCC | 28555341 | ||
| 191 | Phosphorylation | TMVHNRYTPSERAPP HHHHCCCCCCCCCCC | 28555341 | ||
| 200 | Ubiquitination | SERAPPLKSSNQTAP CCCCCCCCCCCCCCC | 21890473 | ||
| 200 | Methylation | SERAPPLKSSNQTAP CCCCCCCCCCCCCCC | - | ||
| 200 | Ubiquitination | SERAPPLKSSNQTAP CCCCCCCCCCCCCCC | 21890473 | ||
| 200 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 200 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 205 | Phosphorylation | PLKSSNQTAPSLNNI CCCCCCCCCCCHHHH | - | ||
| 208 | Phosphorylation | SSNQTAPSLNNIIKA CCCCCCCCHHHHHHH | 25159151 | ||
| 214 | Ubiquitination | PSLNNIIKAATCEGS CCHHHHHHHHCCCCC | 21890473 | ||
| 214 | Methylation | PSLNNIIKAATCEGS CCHHHHHHHHCCCCC | - | ||
| 214 | Ubiquitination | PSLNNIIKAATCEGS CCHHHHHHHHCCCCC | 21890473 | ||
| 214 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 214 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 217 | Phosphorylation | NNIIKAATCEGSESS HHHHHHHCCCCCCCC | 30266825 | ||
| 221 | Phosphorylation | KAATCEGSESSGFGK HHHCCCCCCCCCCCC | 30266825 | ||
| 223 | Phosphorylation | ATCEGSESSGFGKLP HCCCCCCCCCCCCCC | 30266825 | ||
| 224 | Phosphorylation | TCEGSESSGFGKLPK CCCCCCCCCCCCCCC | 30266825 | ||
| 228 | Ubiquitination | SESSGFGKLPKNVSS CCCCCCCCCCCCCHH | 21890473 | ||
| 228 | Acetylation | SESSGFGKLPKNVSS CCCCCCCCCCCCCHH | 26051181 | ||
| 228 | Ubiquitination | SESSGFGKLPKNVSS CCCCCCCCCCCCCHH | 21890473 | ||
| 228 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 228 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 231 | Ubiquitination | SGFGKLPKNVSSATH CCCCCCCCCCHHHCC | - | ||
| 231 (in isoform 2) | Ubiquitination | - | - | ||
| 234 | Phosphorylation | GKLPKNVSSATHSAR CCCCCCCHHHCCCCC | 30576142 | ||
| 244 | Phosphorylation | THSARNNTGGSTGLP CCCCCCCCCCCCCCC | 22167270 | ||
| 247 | Phosphorylation | ARNNTGGSTGLPRRK CCCCCCCCCCCCCCC | 22167270 | ||
| 248 | Phosphorylation | RNNTGGSTGLPRRKE CCCCCCCCCCCCCCC | 22167270 | ||
| 254 | Ubiquitination | STGLPRRKEVTEEEA CCCCCCCCCCCHHHH | 21906983 | ||
| 254 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 254 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 257 | Phosphorylation | LPRRKEVTEEEAERF CCCCCCCCHHHHHHH | 20363803 | ||
| 300 | 2-Hydroxyisobutyrylation | LEHLLQAKREEQRQR HHHHHHHHHHHHHHH | - | ||
| 300 | Ubiquitination | LEHLLQAKREEQRQR HHHHHHHHHHHHHHH | - | ||
| 300 (in isoform 2) | Ubiquitination | - | - | ||
| 308 | Phosphorylation | REEQRQRSGEGTLLD HHHHHHHCCCCCHHH | 30266825 | ||
| 312 | Phosphorylation | RQRSGEGTLLDLHQQ HHHCCCCCHHHHHHH | 30266825 | ||
| 320 | Ubiquitination | LLDLHQQKEAARRKA HHHHHHHHHHHHHHH | 21890473 | ||
| 320 | Ubiquitination | LLDLHQQKEAARRKA HHHHHHHHHHHHHHH | 21890473 | ||
| 320 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 320 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 346 | Ubiquitination | AIQELQQKRALRAQK HHHHHHHHHHHHHHH | - | ||
| 346 (in isoform 2) | Ubiquitination | - | - | ||
| 353 | Ubiquitination | KRALRAQKASTAERG HHHHHHHHHHHHHCC | - | ||
| 353 (in isoform 2) | Ubiquitination | - | - | ||
| 355 | Phosphorylation | ALRAQKASTAERGPP HHHHHHHHHHHCCCC | 28555341 | ||
| 381 | Phosphorylation | RQPAQELSPTPGGTA CCCHHHCCCCCCCHH | 29255136 | ||
| 383 | Phosphorylation | PAQELSPTPGGTAHQ CHHHCCCCCCCHHHH | 30266825 | ||
| 387 | Phosphorylation | LSPTPGGTAHQALKA CCCCCCCHHHHHHHC | 28176443 | ||
| 393 | Ubiquitination | GTAHQALKANNTGGG CHHHHHHHCCCCCCC | 21906983 | ||
| 393 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 393 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 413 | Phosphorylation | PGDRCLPTSDSSPEP CCCCCCCCCCCCCCC | 25159151 | ||
| 414 | Phosphorylation | GDRCLPTSDSSPEPQ CCCCCCCCCCCCCCC | 25159151 | ||
| 416 | Phosphorylation | RCLPTSDSSPEPQQP CCCCCCCCCCCCCCC | 25159151 | ||
| 417 | Phosphorylation | CLPTSDSSPEPQQPP CCCCCCCCCCCCCCC | 25159151 | ||
| 428 | Phosphorylation | QQPPEDRTQDVLAQD CCCCCCCCHHHHHHH | 26074081 | ||
| 447 | Phosphorylation | NLEMMAPSRGSAKSR CCCCCCCCCCCCCCC | 28102081 | ||
| 450 | Phosphorylation | MMAPSRGSAKSRGPL CCCCCCCCCCCCCCH | 28102081 | ||
| 453 | Phosphorylation | PSRGSAKSRGPLEEL CCCCCCCCCCCHHHH | 28450419 | ||
| 485 (in isoform 2) | Phosphorylation | - | 28450419 | ||
| 485 (in isoform 3) | Phosphorylation | - | 28450419 | ||
| 489 | Phosphorylation | RGRYAWASEVTTEDD CCCEEEEEECCCCCC | 30576142 | ||
| 489 (in isoform 2) | Phosphorylation | - | 22617229 | ||
| 489 (in isoform 3) | Phosphorylation | - | 22617229 | ||
| 495 (in isoform 2) | Phosphorylation | - | 22617229 | ||
| 495 (in isoform 3) | Phosphorylation | - | 22617229 | ||
| 496 (in isoform 2) | Phosphorylation | - | 30175587 | ||
| 496 (in isoform 3) | Phosphorylation | - | 30175587 | ||
| 498 | Phosphorylation | VTTEDDASSLTADNL CCCCCCHHHCCHHHH | 29978859 | ||
| 498 (in isoform 2) | Phosphorylation | - | 28450419 | ||
| 498 (in isoform 3) | Phosphorylation | - | 28450419 | ||
| 499 | Phosphorylation | TTEDDASSLTADNLE CCCCCHHHCCHHHHH | 30576142 | ||
| 501 | Phosphorylation | EDDASSLTADNLEKF CCCHHHCCHHHHHHH | 29978859 | ||
| 504 | Ubiquitination | ASSLTADNLEKFGKL HHHCCHHHHHHHCCC | 21890473 | ||
| 504 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 507 | Ubiquitination | LTADNLEKFGKLSAF CCHHHHHHHCCCCCC | 21890473 | ||
| 507 | Ubiquitination | LTADNLEKFGKLSAF CCHHHHHHHCCCCCC | - | ||
| 507 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 510 | Ubiquitination | DNLEKFGKLSAFPEP HHHHHHCCCCCCCCC | 21139048 | ||
| 510 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 519 | Phosphorylation | SAFPEPPEDGTLLSE CCCCCCCCCCCCCCH | - | ||
| 522 | Phosphorylation | PEPPEDGTLLSEAKL CCCCCCCCCCCHHHH | 25850435 | ||
| 525 | Phosphorylation | PEDGTLLSEAKLQSI CCCCCCCCHHHHHHH | 25159151 | ||
| 528 | Phosphorylation | GTLLSEAKLQSIMSF CCCCCHHHHHHHHHH | - | ||
| 531 | Phosphorylation | LSEAKLQSIMSFLDE CCHHHHHHHHHHHHH | 20873877 | ||
| 534 | Phosphorylation | AKLQSIMSFLDEMEK HHHHHHHHHHHHHHH | 22199227 | ||
| 539 | Phosphorylation | IMSFLDEMEKSGQDQ HHHHHHHHHHHCHHH | - | ||
| 542 | Phosphorylation | FLDEMEKSGQDQLDS HHHHHHHHCHHHHHH | 22199227 | ||
| 549 | Phosphorylation | SGQDQLDSQQEGWVP HCHHHHHHCCCCCCC | 22199227 | ||
| 574 | Ubiquitination | SEVSTSVMRLKLEVE CCCCHHHHHHCCCHH | - | ||
| 574 (in isoform 2) | Ubiquitination | - | - | ||
| 598 | Phosphorylation | QRALAQQRDLTARRV HHHHHHCCCHHHHHH | - | ||
| 601 | Phosphorylation | LAQQRDLTARRVKET HHHCCCHHHHHHHHH | 22817900 | ||
| 610 | Phosphorylation | RRVKETEKALSRQLQ HHHHHHHHHHHHHHH | - | ||
| 613 | Phosphorylation | KETEKALSRQLQRQR HHHHHHHHHHHHHHH | 24719451 | ||
| 639 (in isoform 2) | Ubiquitination | - | - | ||
| 644 | Ubiquitination | LIEDKKVLSEKCEAV HHCCHHHHHHHHHHH | - | ||
| 644 (in isoform 2) | Ubiquitination | - | - | ||
| 647 | Ubiquitination | DKKVLSEKCEAVVAE CHHHHHHHHHHHHHH | - | ||
| 653 | Ubiquitination | EKCEAVVAELKQEDQ HHHHHHHHHHHHHHH | - | ||
| 653 (in isoform 2) | Ubiquitination | - | - | ||
| 656 | Ubiquitination | EAVVAELKQEDQRCT HHHHHHHHHHHHHHH | - | ||
| 675 | Ubiquitination | QAQAQHELEIKKLKE HHHHHHHHHHHHHHH | - | ||
| 675 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 676 (in isoform 2) | Ubiquitination | - | - | ||
| 678 | Ubiquitination | AQHELEIKKLKELMS HHHHHHHHHHHHHHH | 21906983 | ||
| 678 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 678 (in isoform 2) | Ubiquitination | - | - | ||
| 681 | Acetylation | ELEIKKLKELMSATE HHHHHHHHHHHHHHH | 26051181 | ||
| 686 | Ubiquitination | KLKELMSATEKARRE HHHHHHHHHHHHHHH | - | ||
| 686 (in isoform 2) | Ubiquitination | - | - | ||
| 689 | Acetylation | ELMSATEKARREKWI HHHHHHHHHHHHHHH | 26051181 | ||
| 696 | Ubiquitination | KARREKWISEKTKKI HHHHHHHHCHHHHHH | - | ||
| 697 | Phosphorylation | ARREKWISEKTKKIK HHHHHHHCHHHHHHH | - | ||
| 701 | Ubiquitination | KWISEKTKKIKEVTV HHHCHHHHHHHEEEH | - | ||
| 701 (in isoform 2) | Ubiquitination | - | - | ||
| 704 | Ubiquitination | SEKTKKIKEVTVRGL CHHHHHHHEEEHHCC | - | ||
| 707 | Phosphorylation | TKKIKEVTVRGLEPE HHHHHEEEHHCCCHH | 24825855 | ||
| 714 | Ubiquitination | TVRGLEPEIQKLIAR EHHCCCHHHHHHHHH | 21890473 | ||
| 714 | Ubiquitination | TVRGLEPEIQKLIAR EHHCCCHHHHHHHHH | - | ||
| 714 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 717 | Ubiquitination | GLEPEIQKLIARHKQ CCCHHHHHHHHHHHH | 21890473 | ||
| 717 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 727 | Methylation | ARHKQEVRRLKSLHE HHHHHHHHHHHHHHH | - | ||
| 727 | Ubiquitination | ARHKQEVRRLKSLHE HHHHHHHHHHHHHHH | - | ||
| 728 | Phosphorylation | RHKQEVRRLKSLHEA HHHHHHHHHHHHHHH | 19413330 | ||
| 730 | Methylation | KQEVRRLKSLHEAEL HHHHHHHHHHHHHHH | - | ||
| 731 | Phosphorylation | QEVRRLKSLHEAELL HHHHHHHHHHHHHHH | 25159151 | ||
| 740 | Phosphorylation | HEAELLQSDERASQR HHHHHHCCHHHHHHH | 28348404 | ||
| 742 | Phosphorylation | AELLQSDERASQRCL HHHHCCHHHHHHHHH | 17525332 | ||
| 745 | Phosphorylation | LQSDERASQRCLRQA HCCHHHHHHHHHHHH | 17525332 | ||
| 795 | Phosphorylation | ALQQQRQRLYSEVAE HHHHHHHHHHHHHHH | - | ||
| 797 | Phosphorylation | QQQRQRLYSEVAEER HHHHHHHHHHHHHHH | 27251275 | ||
| 798 | Phosphorylation | QQRQRLYSEVAEERE HHHHHHHHHHHHHHH | 23401153 | ||
| 856 | Ubiquitination | RRHQMELNTLKQQLE HHHHHHHHHHHHHHH | - | ||
| 857 | Phosphorylation | RHQMELNTLKQQLEL HHHHHHHHHHHHHHH | - | ||
| 873 | Ubiquitination | RQAWEAGRTRKEEAW HHHHHHCCCHHHHHH | - | ||
| 873 (in isoform 2) | Ubiquitination | - | - | ||
| 911 | Sulfoxidation | IHRLEADMALAKEES HHHHHHHHHHHHHHH | 21406390 | ||
| 929 | Ubiquitination | AESRIKRLRDKYEAE HHHHHHHHHHHHHHH | - | ||
| 933 | Phosphorylation | IKRLRDKYEAELSEL HHHHHHHHHHHHHHH | 28509920 | ||
| 938 | Phosphorylation | DKYEAELSELEQSER HHHHHHHHHHHHHHH | 26552605 | ||
| 943 | Phosphorylation | ELSELEQSERKLQER HHHHHHHHHHHHHHH | 28509920 | ||
| 952 | Ubiquitination | RKLQERCSELKGQLG HHHHHHHHHHHHHHC | - | ||
| 952 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 955 | Ubiquitination | QERCSELKGQLGEAE HHHHHHHHHHHCCHH | 2190698 | ||
| 955 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 990 | Phosphorylation | QAVNEQLSSERSNLA HHHHHHHHHHHHHHH | - | ||
| 991 | Phosphorylation | AVNEQLSSERSNLAQ HHHHHHHHHHHHHHH | - | ||
| 994 | Phosphorylation | EQLSSERSNLAQVIR HHHHHHHHHHHHHHH | - | ||
| 1004 | Methylation | AQVIRQEFEDRLAAS HHHHHHHHHHHHHCC | - | ||
| 1007 | Methylation | IRQEFEDRLAASEEE HHHHHHHHHHCCHHH | - | ||
| 1016 | Ubiquitination | AASEEETRQAKAELA HCCHHHHHHHHHHHH | - | ||
| 1024 | Phosphorylation | QAKAELATLQARQQL HHHHHHHHHHHHHHH | - | ||
| 1052 | Phosphorylation | ARKEEAVSSLRTQHE HHHHHHHHHHHHHHH | 24719451 | ||
| 1053 | Phosphorylation | RKEEAVSSLRTQHEA HHHHHHHHHHHHHHH | 24719451 | ||
| 1076 | Phosphorylation | EELLEQHRRPTPSTK HHHHHHCCCCCCCCC | - | ||
| 1079 | Phosphorylation | LEQHRRPTPSTK--- HHHCCCCCCCCC--- | 24719451 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
| 35 | S | Phosphorylation | Kinase | CDKL5 | O76039 | PSP |
| 47 | S | Phosphorylation | Kinase | MAPKAPK2 | P49137 | Uniprot |
| 78 | S | Phosphorylation | Kinase | MAPKAPK2 | P49137 | Uniprot |
| 78 | S | Phosphorylation | Kinase | PLK4 | O00444 | PSP |
| - | K | Ubiquitination | E3 ubiquitin ligase | MIB1 | Q86YT6 | PMID:24121310 |
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CP131_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MIB1_HUMAN | MIB1 | physical | 24121310 | |
| PCM1_HUMAN | PCM1 | physical | 24121310 | |
| PIBF1_HUMAN | PIBF1 | physical | 27173435 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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