CE170_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CE170_HUMAN
• UniProt AC: Q5SW79
• Protein Name: Centrosomal protein of 170 kDa
• Gene Name: CEP170
• Organism: Homo sapiens (Human).
• Sequence Length: 1584
• Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, spindle . Associated with the mature mother centriole. Associated with spindle microtubules during mitosis. Localizes to the distal appendage reg
• Protein Description: Plays a role in microtubule organization. [PubMed: 15616186 Required for centriole subdistal appendage assembly]
• Protein Sequence: MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQDQAVTSSAHHRGGHGVPHGKLLKQKSEEPSVSIPFLQTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSLTSWFLV ------CCCCCEEEE	52.22	22199227
4	Phosphorylation	----MSLTSWFLVSS ----CCCCCEEEECC	32.95	28348404
5	Phosphorylation	---MSLTSWFLVSSG ---CCCCCEEEECCC	22.56	-
10	Phosphorylation	LTSWFLVSSGGTRHR CCCEEEECCCCCCCC	25.97	-
41	Ubiquitination	LQSRSVDKQHAVINY CCCCCCCCCCEEEEE	41.65	29967540
58	Ubiquitination	STDEHLVKDLGSLNG CCCHHHHHHHHHCCC	54.30	29967540
62	Phosphorylation	HLVKDLGSLNGTFVN HHHHHHHHCCCEEEC	26.42	20873877
66	Phosphorylation	DLGSLNGTFVNDVRI HHHHCCCEEECCEEC	24.28	20873877
72	Methylation	GTFVNDVRIPEQTYI CEEECCEECCCCCEE	41.42	-
77	Phosphorylation	DVRIPEQTYITLKLE CEECCCCCEEEEEEH	18.41	28796482
78	Phosphorylation	VRIPEQTYITLKLED EECCCCCEEEEEEHH	7.51	28796482
111	Ubiquitination	RVPEEALKHEKFTIQ CCCHHHHCCCCEEEE	57.68	29967540
122	Phosphorylation	FTIQLQLSQKSSESE EEEEEECCCCCCHHH	23.70	29507054
125	Phosphorylation	QLQLSQKSSESELSK EEECCCCCCHHHHHH	31.53	28348404
126	Phosphorylation	LQLSQKSSESELSKS EECCCCCCHHHHHHH	52.78	26657352
131	Phosphorylation	KSSESELSKSASAKS CCCHHHHHHHHHCHH	22.10	23312004
132	Ubiquitination	SSESELSKSASAKSI CCHHHHHHHHHCHHH	63.77	33845483
133	Phosphorylation	SESELSKSASAKSID CHHHHHHHHHCHHHH	24.87	21712546
135	O-linked_Glycosylation	SELSKSASAKSIDSK HHHHHHHHCHHHHHH	43.23	23301498
135	Phosphorylation	SELSKSASAKSIDSK HHHHHHHHCHHHHHH	43.23	30576142
137	Ubiquitination	LSKSASAKSIDSKVA HHHHHHCHHHHHHHH	45.51	-
138	O-linked_Glycosylation	SKSASAKSIDSKVAD HHHHHCHHHHHHHHH	31.20	23301498
138	Phosphorylation	SKSASAKSIDSKVAD HHHHHCHHHHHHHHH	31.20	26055452
141	Phosphorylation	ASAKSIDSKVADAAT HHCHHHHHHHHHHHH	27.62	21712546
142	Ubiquitination	SAKSIDSKVADAATE HCHHHHHHHHHHHHH	37.38	32015554
148	Phosphorylation	SKVADAATEVQHKTT HHHHHHHHHHHHHHH	38.11	23186163
153	Ubiquitination	AATEVQHKTTEALKS HHHHHHHHHHHHHHH	39.80	33845483
154	Phosphorylation	ATEVQHKTTEALKSE HHHHHHHHHHHHHHH	27.95	20068231
155	Phosphorylation	TEVQHKTTEALKSEE HHHHHHHHHHHHHHH	24.86	20068231
163	Ubiquitination	EALKSEEKAMDISAM HHHHHHHHHHCCCCC	44.98	29967540
168	Phosphorylation	EEKAMDISAMPRGTP HHHHHCCCCCCCCCC	17.79	19060867
174	Phosphorylation	ISAMPRGTPLYGQPS CCCCCCCCCCCCCCC	16.05	25159151
177	Phosphorylation	MPRGTPLYGQPSWWG CCCCCCCCCCCCCCC	18.21	28796482
181	Phosphorylation	TPLYGQPSWWGDDEV CCCCCCCCCCCCCHH	27.81	25159151
191	Ubiquitination	GDDEVDEKRAFKTNG CCCHHHHHHHHHCCC	44.56	32015554
209	Phosphorylation	EKNHEAGTSGCGIDA HCCCCCCCCCCCCCH	29.06	25262027
210	Phosphorylation	KNHEAGTSGCGIDAK CCCCCCCCCCCCCHH	31.03	28857561
223	Phosphorylation	AKQVEEQSAAANEEV HHHHHHHHHHCCCCC	24.13	27251275
239	Phosphorylation	FPFCREPSYFEIPTK ECCCCCCCCCCCCCH	37.39	28348404
240	Phosphorylation	PFCREPSYFEIPTKE CCCCCCCCCCCCCHH	18.88	28796482
245	Phosphorylation	PSYFEIPTKEFQQPS CCCCCCCCHHCCCCC	49.20	29449344
246	Ubiquitination	SYFEIPTKEFQQPSQ CCCCCCCHHCCCCCC	51.69	29967540
252	Phosphorylation	TKEFQQPSQITESTI CHHCCCCCCCCCCEE	29.85	20873877
255	Phosphorylation	FQQPSQITESTIHEI CCCCCCCCCCEEEEC	19.08	29514088
257	Phosphorylation	QPSQITESTIHEIPT CCCCCCCCEEEECCC	24.82	29743597
258	Phosphorylation	PSQITESTIHEIPTK CCCCCCCEEEECCCC	21.81	29743597
264	Phosphorylation	STIHEIPTKDTPSSH CEEEECCCCCCCCCC	47.41	29514088
293	Phosphorylation	DSTPGKVTIRDHVTK CCCCCEEEEEEHHEE	17.49	24719451
300	Methylation	TIRDHVTKFTSDQRH EEEEHHEECCCCHHH	45.62	-
300	Ubiquitination	TIRDHVTKFTSDQRH EEEEHHEECCCCHHH	45.62	33845483
309	Phosphorylation	TSDQRHKSKKSSPGT CCCHHHCCCCCCCCH	38.91	21712546
312	Phosphorylation	QRHKSKKSSPGTQDL HHHCCCCCCCCHHHH	45.56	23401153
313	Phosphorylation	RHKSKKSSPGTQDLL HHCCCCCCCCHHHHH	35.91	25159151
316	Phosphorylation	SKKSSPGTQDLLGIQ CCCCCCCHHHHHCCC	23.46	25159151
324	Phosphorylation	QDLLGIQTGMMAPEN HHHHCCCCCCCCCCH	25.73	29396449
350	Phosphorylation	PQMLWERTEEDSKSI CCHHHCCCHHHHHHH	32.01	23403867
354	Phosphorylation	WERTEEDSKSIKSDV HCCCHHHHHHHHCCC	31.42	23927012
356	Phosphorylation	RTEEDSKSIKSDVPV CCHHHHHHHHCCCCH	38.92	19664994
358	Ubiquitination	EEDSKSIKSDVPVYL HHHHHHHHCCCCHHH	47.93	33845483
359	Phosphorylation	EDSKSIKSDVPVYLK HHHHHHHCCCCHHHH	42.02	19664994
364	Phosphorylation	IKSDVPVYLKRLKGN HHCCCCHHHHHHCCC	10.63	25159151
366	Ubiquitination	SDVPVYLKRLKGNKH CCCCHHHHHHCCCCC	37.69	32015554
377	Phosphorylation	GNKHDDGTQSDSENA CCCCCCCCCCHHHCC	31.71	22167270
379	Phosphorylation	KHDDGTQSDSENAGA CCCCCCCCHHHCCCH	42.83	29255136
381	Phosphorylation	DDGTQSDSENAGAHR CCCCCCHHHCCCHHH	37.69	22167270
391	Phosphorylation	AGAHRRCSKRATLEE CCHHHHHHHHHHHHH	24.30	26074081
395	Phosphorylation	RRCSKRATLEEHLRR HHHHHHHHHHHHHHH	38.44	23312004
405	Phosphorylation	EHLRRHHSEHKKLQK HHHHHHHHHHHHHHH	34.96	24706070
409	Ubiquitination	RHHSEHKKLQKVQAT HHHHHHHHHHHHHCC	59.04	29967540
412	Ubiquitination	SEHKKLQKVQATEKH HHHHHHHHHHCCHHH	46.91	29967540
431	Methylation	VTSSAHHRGGHGVPH HHCCCCCCCCCCCCC	42.81	-
434 (in isoform 2)	Phosphorylation	-	36.58	28796482
434 (in isoform 3)	Phosphorylation	-	36.58	28796482
440	Acetylation	GHGVPHGKLLKQKSE CCCCCCHHHCCCCCC	47.84	25953088
440	Methylation	GHGVPHGKLLKQKSE CCCCCCHHHCCCCCC	47.84	-
446	Phosphorylation	GKLLKQKSEEPSVSI HHHCCCCCCCCCCCH	44.70	29255136
450	Phosphorylation	KQKSEEPSVSIPFLQ CCCCCCCCCCHHHHH	31.60	30266825
452	Phosphorylation	KSEEPSVSIPFLQTA CCCCCCCCHHHHHHH	28.96	30266825
458	Phosphorylation	VSIPFLQTALLRSSG CCHHHHHHHHHHCCC	22.78	23403867
463	Phosphorylation	LQTALLRSSGSLGHR HHHHHHHCCCCCCCC	38.73	23927012
463	Ubiquitination	LQTALLRSSGSLGHR HHHHHHHCCCCCCCC	38.73	29967540
464	Phosphorylation	QTALLRSSGSLGHRP HHHHHHCCCCCCCCC	26.43	20201521
466	Phosphorylation	ALLRSSGSLGHRPSQ HHHHCCCCCCCCCHH	32.88	23927012
472	Phosphorylation	GSLGHRPSQEMDKML CCCCCCCHHHHHHHH	38.44	23927012
484	Phosphorylation	KMLKNQATSATSEKD HHHHHHHCCCCCCCC	14.77	23927012
485	Phosphorylation	MLKNQATSATSEKDN HHHHHHCCCCCCCCC	32.34	23927012
487	Phosphorylation	KNQATSATSEKDNDD HHHHCCCCCCCCCCC	36.87	23927012
488	Phosphorylation	NQATSATSEKDNDDD HHHCCCCCCCCCCCC	42.22	25159151
497	Phosphorylation	KDNDDDQSDKGTYTI CCCCCCCCCCCEEEE	48.56	29255136
501	Phosphorylation	DDQSDKGTYTIELEN CCCCCCCEEEEEEEC	24.19	29255136
502	Phosphorylation	DQSDKGTYTIELENP CCCCCCEEEEEEECC	17.87	29255136
503	Phosphorylation	QSDKGTYTIELENPN CCCCCEEEEEEECCC	14.07	29255136
511	Phosphorylation	IELENPNSEEVEARK EEEECCCHHHHHHHH	36.07	23403867
522	Ubiquitination	EARKMIDKVFGVDDN HHHHHHHHHHCCCCC	28.65	29967540
532	Phosphorylation	GVDDNQDYNRPVINE CCCCCCCCCCCCCCH	11.87	28796482
538	Phosphorylation	DYNRPVINEKHKDLI CCCCCCCCHHHHHHH	53.12	33259812
546	Phosphorylation	EKHKDLIKDWALSSA HHHHHHHHHHHHHHH	55.29	32142685
561	Ubiquitination	AAVMEERKPLTTSGF HHHHHHCCCCCCCCC	47.89	29967540
564	Phosphorylation	MEERKPLTTSGFHHS HHHCCCCCCCCCCCC	27.69	20873877
565	Phosphorylation	EERKPLTTSGFHHSE HHCCCCCCCCCCCCC	34.24	20068231
566	Phosphorylation	ERKPLTTSGFHHSEE HCCCCCCCCCCCCCC	33.94	23927012
571	Phosphorylation	TTSGFHHSEEGTSSS CCCCCCCCCCCCCCC	28.86	23927012
575	Phosphorylation	FHHSEEGTSSSGSKR CCCCCCCCCCCCCHH	28.81	23927012
576	Phosphorylation	HHSEEGTSSSGSKRW CCCCCCCCCCCCHHH	33.10	20201521
577	Phosphorylation	HSEEGTSSSGSKRWV CCCCCCCCCCCHHHH	38.26	30576142
578	Phosphorylation	SEEGTSSSGSKRWVS CCCCCCCCCCHHHHH	47.02	30576142
580	Phosphorylation	EGTSSSGSKRWVSQW CCCCCCCCHHHHHHH	22.46	20201521
607	Phosphorylation	EERIMEFSAPLPLEN HHHHHHHCCCCCCCC	18.70	27251275
616	Phosphorylation	PLPLENETEISESGM CCCCCCCCEECCCCC	50.64	28450419
619	Phosphorylation	LENETEISESGMTVR CCCCCEECCCCCEEE	21.34	28450419
621	Phosphorylation	NETEISESGMTVRST CCCEECCCCCEEEEC	27.37	28450419
624	Phosphorylation	EISESGMTVRSTGSA EECCCCCEEEECCCC	19.12	28450419
627	Phosphorylation	ESGMTVRSTGSATSL CCCCEEEECCCCHHH	32.55	29255136
628	O-linked_Glycosylation	SGMTVRSTGSATSLA CCCEEEECCCCHHHH	25.29	23301498
628	Phosphorylation	SGMTVRSTGSATSLA CCCEEEECCCCHHHH	25.29	29255136
630	Phosphorylation	MTVRSTGSATSLASQ CEEEECCCCHHHHHH	28.58	29255136
632	Phosphorylation	VRSTGSATSLASQGE EEECCCCHHHHHHHH	26.43	23927012
633	Phosphorylation	RSTGSATSLASQGER EECCCCHHHHHHHHH	22.96	17525332
636	Phosphorylation	GSATSLASQGERRRR CCCHHHHHHHHHHHC	43.97	25159151
644	Phosphorylation	QGERRRRTLPQLPNE HHHHHHCCCCCCCCH	40.76	29255136
644	Ubiquitination	QGERRRRTLPQLPNE HHHHHHCCCCCCCCH	40.76	32142685
649	Ubiquitination	RRTLPQLPNEEKSLE HCCCCCCCCHHHHHH	40.72	29967540
654	Phosphorylation	QLPNEEKSLESHRAK CCCCHHHHHHHHHHH	40.42	24719451
664	Phosphorylation	SHRAKVVTQRSEIGE HHHHHHHHHHHHHCC	22.66	23401153
665	Ubiquitination	HRAKVVTQRSEIGEK HHHHHHHHHHHHCCC	34.98	32142685
667	Phosphorylation	AKVVTQRSEIGEKQD HHHHHHHHHHCCCCC	24.61	23401153
675	Phosphorylation	EIGEKQDTELQEKET HHCCCCCCHHHCCCC	35.78	23403867
682	Phosphorylation	TELQEKETPTQVYQK CHHHCCCCCCCHHHH	42.58	19691289
684	Phosphorylation	LQEKETPTQVYQKDK HHCCCCCCCHHHHCH	37.78	19691289
712	Phosphorylation	VNGETLKTGGDNKTL HCCCEECCCCCCCEE	49.89	-
718	Phosphorylation	KTGGDNKTLLHLGSS CCCCCCCEEEECCCC	40.58	23186163
724	Phosphorylation	KTLLHLGSSAPGKEK CEEEECCCCCCCCCC	29.68	25159151
725	Phosphorylation	TLLHLGSSAPGKEKS EEEECCCCCCCCCCC	36.36	29507054
729	Acetylation	LGSSAPGKEKSETDK CCCCCCCCCCCCCHH	61.99	23236377
732	Phosphorylation	SAPGKEKSETDKETS CCCCCCCCCCHHHHH	46.98	29214152
734	Phosphorylation	PGKEKSETDKETSLV CCCCCCCCHHHHHHH	60.50	20860994
736	Acetylation	KEKSETDKETSLVKQ CCCCCCHHHHHHHHH	71.02	25953088
738	Phosphorylation	KSETDKETSLVKQTL CCCCHHHHHHHHHHH	32.85	19691289
739	Phosphorylation	SETDKETSLVKQTLA CCCHHHHHHHHHHHH	32.05	19691289
742	Ubiquitination	DKETSLVKQTLAKLQ HHHHHHHHHHHHHHH	42.74	32142685
747	Ubiquitination	LVKQTLAKLQQQEQR HHHHHHHHHHHHHHH	50.36	29967540
760	Phosphorylation	QREEAQWTPTKLSSK HHHHHCCCCCCHHHC	14.70	25159151
762	Phosphorylation	EEAQWTPTKLSSKNV HHHCCCCCCHHHCCC	36.92	28450419
763	Ubiquitination	EAQWTPTKLSSKNVS HHCCCCCCHHHCCCC	47.80	32142685
765	Phosphorylation	QWTPTKLSSKNVSGQ CCCCCCHHHCCCCCC	40.60	26074081
766	Phosphorylation	WTPTKLSSKNVSGQT CCCCCHHHCCCCCCC	38.39	26074081
783	Phosphorylation	CREETFKQESQPPEK HHHHHHHCCCCCCCC	51.92	32142685
785	Phosphorylation	EETFKQESQPPEKNS HHHHHCCCCCCCCCC	45.56	22985185
818	Phosphorylation	KAEEILKSQTPKGGD HHHHHHHHCCCCCCC	35.52	29214152
820	Phosphorylation	EEILKSQTPKGGDKK HHHHHHCCCCCCCCH	33.78	21712546
829	Phosphorylation	KGGDKKESSKSLVRQ CCCCCHHHCHHHHHC	52.53	26074081
830	Phosphorylation	GGDKKESSKSLVRQG CCCCHHHCHHHHHCC	27.62	26074081
832	Phosphorylation	DKKESSKSLVRQGSF CCHHHCHHHHHCCCE	33.76	22199227
835	Phosphorylation	ESSKSLVRQGSFTIE HHCHHHHHCCCEEEC	40.20	32142685
838	Phosphorylation	KSLVRQGSFTIEKPS HHHHHCCCEEECCCC	15.75	29255136
840	Phosphorylation	LVRQGSFTIEKPSPN HHHCCCEEECCCCCC	29.89	29255136
845	Phosphorylation	SFTIEKPSPNIPIEL CEEECCCCCCCCCCC	41.46	22167270
860	Phosphorylation	IPHINKQTSSTPSSL CCCCCCCCCCCHHHH	26.67	19691289
861	Phosphorylation	PHINKQTSSTPSSLA CCCCCCCCCCHHHHH	29.71	19691289
862	Phosphorylation	HINKQTSSTPSSLAL CCCCCCCCCHHHHHH	47.96	19691289
863	Phosphorylation	INKQTSSTPSSLALT CCCCCCCCHHHHHHH	27.27	25159151
865	Phosphorylation	KQTSSTPSSLALTSA CCCCCCHHHHHHHHH	37.76	19691289
866	Phosphorylation	QTSSTPSSLALTSAS CCCCCHHHHHHHHHH	20.90	19691289
870	O-linked_Glycosylation	TPSSLALTSASRIRE CHHHHHHHHHHHHHH	19.35	23301498
870	Phosphorylation	TPSSLALTSASRIRE CHHHHHHHHHHHHHH	19.35	25627689
871	Phosphorylation	PSSLALTSASRIRER HHHHHHHHHHHHHHH	25.71	25159151
873	Phosphorylation	SLALTSASRIRERSE HHHHHHHHHHHHHHH	28.18	17081983
879	Phosphorylation	ASRIRERSESLDPDS HHHHHHHHHCCCCCC	27.12	29255136
881	Phosphorylation	RIRERSESLDPDSSM HHHHHHHCCCCCCCC	39.04	29255136
886	Phosphorylation	SESLDPDSSMDTTLI HHCCCCCCCCCCEEE	32.71	30266825
887	Phosphorylation	ESLDPDSSMDTTLIL HCCCCCCCCCCEEEE	28.23	30266825
890	Phosphorylation	DPDSSMDTTLILKDT CCCCCCCCEEEECCH	18.17	28176443
891	Phosphorylation	PDSSMDTTLILKDTE CCCCCCCEEEECCHH	13.92	28176443
914	Phosphorylation	KLREDNKTDEGPDTP HHHHCCCCCCCCCCC	45.60	27273156
920	Phosphorylation	KTDEGPDTPSYNRDN CCCCCCCCCCCCCCC	19.78	27273156
921	Phosphorylation	TDEGPDTPSYNRDNS CCCCCCCCCCCCCCC	42.04	32142685
922	Phosphorylation	DEGPDTPSYNRDNSI CCCCCCCCCCCCCCC	36.81	19691289
923	Phosphorylation	EGPDTPSYNRDNSIS CCCCCCCCCCCCCCC	18.54	29396449
928	Phosphorylation	PSYNRDNSISPESDV CCCCCCCCCCCCCCC	28.82	30266825
930	Phosphorylation	YNRDNSISPESDVDT CCCCCCCCCCCCCCC	23.57	30266825
933	Phosphorylation	DNSISPESDVDTAST CCCCCCCCCCCCHHH	46.44	30266825
937	Phosphorylation	SPESDVDTASTISLV CCCCCCCCHHHHHHH	23.50	30266825
939	Phosphorylation	ESDVDTASTISLVTG CCCCCCHHHHHHHCC	28.50	30266825
939	Ubiquitination	ESDVDTASTISLVTG CCCCCCHHHHHHHCC	28.50	24816145
940	Phosphorylation	SDVDTASTISLVTGE CCCCCHHHHHHHCCC	16.48	30266825
942	Phosphorylation	VDTASTISLVTGETE CCCHHHHHHHCCCCC	19.51	30266825
945	Phosphorylation	ASTISLVTGETERKS HHHHHHHCCCCCCCC	34.29	23403867
948	Phosphorylation	ISLVTGETERKSTQK HHHHCCCCCCCCCHH	42.29	23403867
958	Phosphorylation	KSTQKRKSFTSLYKD CCCHHCHHHHHHHHC	37.48	22167270
960	Phosphorylation	TQKRKSFTSLYKDRC CHHCHHHHHHHHCCC	25.55	22167270
961	Phosphorylation	QKRKSFTSLYKDRCS HHCHHHHHHHHCCCC	27.91	23401153
963	Phosphorylation	RKSFTSLYKDRCSTG CHHHHHHHHCCCCCC	15.60	23403867
964	Malonylation	KSFTSLYKDRCSTGS HHHHHHHHCCCCCCC	43.95	26320211
968	Phosphorylation	SLYKDRCSTGSPSKD HHHHCCCCCCCCCCC	36.38	20873877
969	Phosphorylation	LYKDRCSTGSPSKDV HHHCCCCCCCCCCCC	45.35	26657352
971	Phosphorylation	KDRCSTGSPSKDVTK HCCCCCCCCCCCCHH	26.53	23401153
973	Phosphorylation	RCSTGSPSKDVTKSS CCCCCCCCCCCHHCC	43.09	28450419
977	Phosphorylation	GSPSKDVTKSSSSGA CCCCCCCHHCCCCHH	35.03	20873877
980	Phosphorylation	SKDVTKSSSSGAREK CCCCHHCCCCHHHHH	30.03	30576142
981	Phosphorylation	KDVTKSSSSGAREKM CCCHHCCCCHHHHHH	39.62	30576142
982	Phosphorylation	DVTKSSSSGAREKME CCHHCCCCHHHHHHH	38.12	30576142
1011	Phosphorylation	DGRKFVQSSGRIRQP CCHHHHHCCCCCCCC	29.47	26261332
1012	Phosphorylation	GRKFVQSSGRIRQPS CHHHHHCCCCCCCCC	18.26	26261332
1016	Phosphorylation	VQSSGRIRQPSVDLT HHCCCCCCCCCCCCC	40.78	32142685
1019	Phosphorylation	SGRIRQPSVDLTDDD CCCCCCCCCCCCCCC	21.67	27273156
1023	Phosphorylation	RQPSVDLTDDDQTSS CCCCCCCCCCCCCCC	32.68	27273156
1028	Phosphorylation	DLTDDDQTSSVPHSA CCCCCCCCCCCCHHH	29.93	22617229
1029	Phosphorylation	LTDDDQTSSVPHSAI CCCCCCCCCCCHHHH	24.57	24043423
1030	Phosphorylation	TDDDQTSSVPHSAIS CCCCCCCCCCHHHHH	42.95	30576142
1034	Phosphorylation	QTSSVPHSAISDIMS CCCCCCHHHHHHHHH	22.64	30576142
1037	Phosphorylation	SVPHSAISDIMSSDQ CCCHHHHHHHHHCCC	22.32	30576142
1037	Ubiquitination	SVPHSAISDIMSSDQ CCCHHHHHHHHHCCC	22.32	24816145
1041	Phosphorylation	SAISDIMSSDQETYS HHHHHHHHCCCCEEC	30.97	24043423
1042	Phosphorylation	AISDIMSSDQETYSC HHHHHHHCCCCEECC	26.40	24043423
1046	Phosphorylation	IMSSDQETYSCKPHG HHHCCCCEECCCCCC	18.33	20873877
1047	Phosphorylation	MSSDQETYSCKPHGR HHCCCCEECCCCCCC	16.00	20873877
1048	Phosphorylation	SSDQETYSCKPHGRT HCCCCEECCCCCCCC	24.08	20873877
1055	Phosphorylation	SCKPHGRTPLTSADE CCCCCCCCCCCCCCH	27.52	29255136
1058	Phosphorylation	PHGRTPLTSADEHVH CCCCCCCCCCCHHHH	24.07	30266825
1059	Phosphorylation	HGRTPLTSADEHVHS CCCCCCCCCCHHHHH	41.21	23401153
1066	Phosphorylation	SADEHVHSKLEGSKV CCCHHHHHHHCCCCC	37.54	23403867
1067	Phosphorylation	ADEHVHSKLEGSKVT CCHHHHHHHCCCCCC	35.36	32142685
1071	Phosphorylation	VHSKLEGSKVTKSKT HHHHHCCCCCCCCCC	17.99	23403867
1074	Phosphorylation	KLEGSKVTKSKTSPV HHCCCCCCCCCCCCC	33.08	26657352
1076	Phosphorylation	EGSKVTKSKTSPVVS CCCCCCCCCCCCCCC	31.62	26657352
1078	Phosphorylation	SKVTKSKTSPVVSGS CCCCCCCCCCCCCCC	45.41	25159151
1079	Phosphorylation	KVTKSKTSPVVSGSS CCCCCCCCCCCCCCC	21.31	25159151
1083	Phosphorylation	SKTSPVVSGSSSKST CCCCCCCCCCCCCCC	32.94	23403867
1085	Phosphorylation	TSPVVSGSSSKSTTL CCCCCCCCCCCCCCC	24.75	23403867
1086	Phosphorylation	SPVVSGSSSKSTTLP CCCCCCCCCCCCCCC	45.36	23403867
1087	Phosphorylation	PVVSGSSSKSTTLPR CCCCCCCCCCCCCCC	32.11	23403867
1089	Phosphorylation	VSGSSSKSTTLPRPR CCCCCCCCCCCCCCC	28.68	27732954
1090	Phosphorylation	SGSSSKSTTLPRPRP CCCCCCCCCCCCCCC	35.77	27732954
1091	Phosphorylation	GSSSKSTTLPRPRPT CCCCCCCCCCCCCCC	41.68	23403867
1098	Phosphorylation	TLPRPRPTRTSLLRR CCCCCCCCCHHHHHH	48.10	29449344
1098	Ubiquitination	TLPRPRPTRTSLLRR CCCCCCCCCHHHHHH	48.10	24816145
1099	Ubiquitination	LPRPRPTRTSLLRRA CCCCCCCCHHHHHHH	25.63	24816145
1100	Phosphorylation	PRPRPTRTSLLRRAR CCCCCCCHHHHHHHH	26.63	32142685
1101	Phosphorylation	RPRPTRTSLLRRARL CCCCCCHHHHHHHHH	23.32	24719451
1112	Phosphorylation	RARLGEASDSELADA HHHHCCCCHHHHCHH	37.05	29255136
1114	Phosphorylation	RLGEASDSELADADK HHCCCCHHHHCHHHH	31.82	30266825
1118 (in isoform 2)	Phosphorylation	-	68.85	20068231
1120 (in isoform 2)	Phosphorylation	-	47.83	20068231
1121 (in isoform 2)	Phosphorylation	-	44.26	25627689
1123	Phosphorylation	LADADKASVASEVST HCHHHHHHHCCCCCC	24.77	20068231
1125 (in isoform 2)	Phosphorylation	-	9.47	-
1126	Phosphorylation	ADKASVASEVSTTSS HHHHHHCCCCCCCCC	36.05	23927012
1127 (in isoform 2)	Phosphorylation	-	30.65	25627689
1129	Phosphorylation	ASVASEVSTTSSTSK HHHCCCCCCCCCCCC	23.16	23927012
1130	Phosphorylation	SVASEVSTTSSTSKP HHCCCCCCCCCCCCC	35.55	23927012
1131	Phosphorylation	VASEVSTTSSTSKPP HCCCCCCCCCCCCCC	17.11	23927012
1132	Phosphorylation	ASEVSTTSSTSKPPT CCCCCCCCCCCCCCC	31.54	23927012
1133	Phosphorylation	SEVSTTSSTSKPPTG CCCCCCCCCCCCCCC	34.31	23927012
1134	Phosphorylation	EVSTTSSTSKPPTGR CCCCCCCCCCCCCCC	40.30	23663014
1135	Phosphorylation	VSTTSSTSKPPTGRR CCCCCCCCCCCCCCC	45.15	20068231
1136 (in isoform 2)	Phosphorylation	-	55.92	25627689
1139	Phosphorylation	SSTSKPPTGRRNISR CCCCCCCCCCCCCCH	52.42	20873877
1142	Phosphorylation	SKPPTGRRNISRIDL CCCCCCCCCCCHHHH	46.29	32645325
1143	Phosphorylation	KPPTGRRNISRIDLL CCCCCCCCCCHHHHH	34.92	32142685
1145	Phosphorylation	PTGRRNISRIDLLAQ CCCCCCCCHHHHHCC	27.08	22617229
1156	Phosphorylation	LLAQPRRTRLGSLSA HHCCCCCCCCCCCCC	31.37	23312004
1160	Phosphorylation	PRRTRLGSLSARSDS CCCCCCCCCCCCCCC	24.60	29255136
1162	Phosphorylation	RTRLGSLSARSDSEA CCCCCCCCCCCCCCC	24.27	29255136
1165	O-linked_Glycosylation	LGSLSARSDSEATIS CCCCCCCCCCCCEEC	45.25	23301498
1165	Phosphorylation	LGSLSARSDSEATIS CCCCCCCCCCCCEEC	45.25	29255136
1167	Phosphorylation	SLSARSDSEATISRS CCCCCCCCCCEECCC	30.31	29255136
1170	Phosphorylation	ARSDSEATISRSSAS CCCCCCCEECCCCCC	18.55	30266825
1172	Phosphorylation	SDSEATISRSSASSR CCCCCEECCCCCCHH	23.04	30266825
1178	Phosphorylation	ISRSSASSRTAEAII ECCCCCCHHHHHHHH	33.11	28555341
1180	Phosphorylation	RSSASSRTAEAIIRS CCCCCHHHHHHHHHC	30.69	29255136
1194	Phosphorylation	SGARLVPSDKFSPRI CCCEECCCCCCCHHH	46.05	29255136
1196	Ubiquitination	ARLVPSDKFSPRIRA CEECCCCCCCHHHCC	52.67	24816145
1198	Phosphorylation	LVPSDKFSPRIRANS ECCCCCCCHHHCCCH	21.00	29255136
1205	Phosphorylation	SPRIRANSISRLSDS CHHHCCCHHHHCCHH	22.43	27273156
1207	Phosphorylation	RIRANSISRLSDSKV HHCCCHHHHCCHHHC	27.30	26846344
1209 (in isoform 2)	Phosphorylation	-	5.50	25159151
1210	Phosphorylation	ANSISRLSDSKVKSM CCHHHHCCHHHCCCC	38.43	25159151
1212	Phosphorylation	SISRLSDSKVKSMTS HHHHCCHHHCCCCCC	35.65	23403867
1215	Methylation	RLSDSKVKSMTSAHG HCCHHHCCCCCCCCC	37.94	-
1216	Phosphorylation	LSDSKVKSMTSAHGS CCHHHCCCCCCCCCC	30.22	25159151
1218	Phosphorylation	DSKVKSMTSAHGSAS HHHCCCCCCCCCCHH	29.83	23312004
1219	Phosphorylation	SKVKSMTSAHGSASV HHCCCCCCCCCCHHH	15.04	25159151
1223	Phosphorylation	SMTSAHGSASVNSRW CCCCCCCCHHHHHCH	13.91	25159151
1225	Phosphorylation	TSAHGSASVNSRWRR CCCCCCHHHHHCHHC	24.43	25159151
1228	Phosphorylation	HGSASVNSRWRRFPT CCCHHHHHCHHCCCC	30.94	25159151
1235	Phosphorylation	SRWRRFPTDYASTSE HCHHCCCCCCCCCCC	38.64	23927012
1237	Phosphorylation	WRRFPTDYASTSEDE HHCCCCCCCCCCCCC	12.63	29255136
1238 (in isoform 2)	Phosphorylation	-	14.78	25159151
1239	Phosphorylation	RFPTDYASTSEDEFG CCCCCCCCCCCCCCC	26.66	18388127
1240	Phosphorylation	FPTDYASTSEDEFGS CCCCCCCCCCCCCCC	28.15	18388127
1241	Phosphorylation	PTDYASTSEDEFGSN CCCCCCCCCCCCCCC	40.32	18388127
1247	Phosphorylation	TSEDEFGSNRNSPKH CCCCCCCCCCCCCCC	37.63	29255136
1251	Phosphorylation	EFGSNRNSPKHTRLR CCCCCCCCCCCCCCC	31.89	29255136
1252	Phosphorylation	FGSNRNSPKHTRLRT CCCCCCCCCCCCCCC	35.68	32142685
1255	Phosphorylation	NRNSPKHTRLRTSPA CCCCCCCCCCCCCCC	37.21	29514088
1258	Ubiquitination	SPKHTRLRTSPALKT CCCCCCCCCCCCHHH	29.84	24816145
1259	Phosphorylation	PKHTRLRTSPALKTT CCCCCCCCCCCHHHH	43.59	30266825
1260	Phosphorylation	KHTRLRTSPALKTTR CCCCCCCCCCHHHHC	11.18	30266825
1264	Acetylation	LRTSPALKTTRLQSA CCCCCCHHHHCCCCC	50.37	25953088
1265	Phosphorylation	RTSPALKTTRLQSAG CCCCCHHHHCCCCCC	20.28	20068231
1266	Phosphorylation	TSPALKTTRLQSAGS CCCCHHHHCCCCCCC	28.00	20068231
1269	Ubiquitination	ALKTTRLQSAGSAMP CHHHHCCCCCCCCCC	28.13	29967540
1270	Phosphorylation	LKTTRLQSAGSAMPT HHHHCCCCCCCCCCC	38.91	25159151
1273	Phosphorylation	TRLQSAGSAMPTSSS HCCCCCCCCCCCCHH	22.55	28555341
1275	Sulfoxidation	LQSAGSAMPTSSSFK CCCCCCCCCCCHHHH	3.89	21406390
1277	Phosphorylation	SAGSAMPTSSSFKHR CCCCCCCCCHHHHHH	28.31	23401153
1278	Phosphorylation	AGSAMPTSSSFKHRI CCCCCCCCHHHHHHH	20.36	25159151
1279	Phosphorylation	GSAMPTSSSFKHRIK CCCCCCCHHHHHHHH	42.12	23401153
1280	Phosphorylation	SAMPTSSSFKHRIKE CCCCCCHHHHHHHHH	37.77	23401153
1282	Methylation	MPTSSSFKHRIKEQE CCCCHHHHHHHHHHH	33.64	-
1283	Phosphorylation	PTSSSFKHRIKEQED CCCHHHHHHHHHHHH	34.39	32142685
1291	Phosphorylation	RIKEQEDYIRDWTAH HHHHHHHHHHHHHHC	9.34	26552605
1296	Phosphorylation	EDYIRDWTAHREEIA HHHHHHHHHCHHHHH	19.51	28509920
1306	Phosphorylation	REEIARISQDLALIA HHHHHHHHHHHHHHH	16.46	29255136
1309	Phosphorylation	IARISQDLALIAREI HHHHHHHHHHHHHHH	3.03	32142685
1331	Phosphorylation	DSVTSSGTAPSTTVS CCCCCCCCCCCCEEE	37.03	27690223
1332	Ubiquitination	SVTSSGTAPSTTVST CCCCCCCCCCCEEEC	10.28	29967540
1334	Phosphorylation	TSSGTAPSTTVSTAA CCCCCCCCCEEECCC	33.96	27690223
1335	Phosphorylation	SSGTAPSTTVSTAAT CCCCCCCCEEECCCC	30.11	27690223
1336	Phosphorylation	SGTAPSTTVSTAATT CCCCCCCEEECCCCC	19.45	27690223
1338	Phosphorylation	TAPSTTVSTAATTPG CCCCCEEECCCCCCC	15.38	29978859
1339	Phosphorylation	APSTTVSTAATTPGS CCCCEEECCCCCCCC	18.90	29978859
1342	Phosphorylation	TTVSTAATTPGSAID CEEECCCCCCCCCCC	30.93	29978859
1343	Phosphorylation	TVSTAATTPGSAIDT EEECCCCCCCCCCCC	22.41	25159151
1346	Phosphorylation	TAATTPGSAIDTREE CCCCCCCCCCCCHHH	24.21	29978859
1350	Phosphorylation	TPGSAIDTREELVDR CCCCCCCCHHHHHHH	33.59	27690223
1358	Ubiquitination	REELVDRVFDESLNF HHHHHHHHHHHCCCC	6.49	29967540
1362	Phosphorylation	VDRVFDESLNFRKIP HHHHHHHCCCCCCCC	30.38	29255136
1367	Ubiquitination	DESLNFRKIPPLVHS HHCCCCCCCCCCCCC	56.26	29967540
1374	Phosphorylation	KIPPLVHSKTPEGNN CCCCCCCCCCCCCCC	30.64	22199227
1376	Phosphorylation	PPLVHSKTPEGNNGR CCCCCCCCCCCCCCC	29.59	21712546
1384	Phosphorylation	PEGNNGRSGDPRPQA CCCCCCCCCCCCCCC	49.28	25159151
1397	Phosphorylation	QAAEPPDHLTITRRR CCCCCCCCEEEEECC	30.55	32142685
1399	Phosphorylation	AEPPDHLTITRRRTW CCCCCCEEEEECCCC	19.51	28555341
1405	Phosphorylation	LTITRRRTWSRDEVM EEEEECCCCCCCHHH	26.44	27273156
1407	Phosphorylation	ITRRRTWSRDEVMGD EEECCCCCCCHHHCC	29.28	27273156
1419	Phosphorylation	MGDNLLLSSVFQFSK HCCCHHHHHHHHHHH	25.15	28122231
1420	Phosphorylation	GDNLLLSSVFQFSKK CCCHHHHHHHHHHHH	27.24	28122231
1423	Phosphorylation	LLLSSVFQFSKKIRQ HHHHHHHHHHHHHHH	39.28	32142685
1431	Phosphorylation	FSKKIRQSIDKTAGK HHHHHHHHHHHHCCE	23.94	18669648
1435	Phosphorylation	IRQSIDKTAGKIRIL HHHHHHHHCCEEEEE	36.57	18669648
1456	Ubiquitination	NWDDIESKLRAESEV CHHHHHHHHHHHCCC	29.24	29967540
1461	Phosphorylation	ESKLRAESEVPIVKT HHHHHHHCCCCEEEC	42.80	20873877
1468	Phosphorylation	SEVPIVKTSSMEISS CCCCEEECCCHHHHH	18.36	23403867
1469	Phosphorylation	EVPIVKTSSMEISSI CCCEEECCCHHHHHH	23.21	28348404
1470	Phosphorylation	VPIVKTSSMEISSIL CCEEECCCHHHHHHH	26.18	23403867
1474	Phosphorylation	KTSSMEISSILQELK ECCCHHHHHHHHHHH	9.68	23403867
1475	Phosphorylation	TSSMEISSILQELKR CCCHHHHHHHHHHHH	32.74	23403867
1481	Ubiquitination	SSILQELKRVEKQLQ HHHHHHHHHHHHHHH	54.36	-
1499	Phosphorylation	AMIDPDGTLEALNNM HHCCCCCHHHHHHHC	28.89	25850435
1510	Phosphorylation	LNNMGFPSAMLPSPP HHHCCCCHHHCCCCC	24.85	26657352
1515	Phosphorylation	FPSAMLPSPPKQKSS CCHHHCCCCCCCCCC	50.28	25159151
1521	Phosphorylation	PSPPKQKSSPVNNHH CCCCCCCCCCCCCCC	37.06	23927012
1522	Phosphorylation	SPPKQKSSPVNNHHS CCCCCCCCCCCCCCC	39.64	23927012
1529	Phosphorylation	SPVNNHHSPGQTPTL CCCCCCCCCCCCCCC	24.15	23927012
1533	Phosphorylation	NHHSPGQTPTLGQPE CCCCCCCCCCCCCCC	24.93	23927012
1535	Phosphorylation	HSPGQTPTLGQPEAR CCCCCCCCCCCCCHH	47.08	23927012
1550	Phosphorylation	ALHPAAVSAAAEFEN HHCHHHHHHHHHHCC	13.89	28060719
1560	Phosphorylation	AEFENAESEADFSIH HHHCCCCCCCCEEEE	35.36	29255136
1565	Phosphorylation	AESEADFSIHFNRFN CCCCCCEEEEEECCC	18.72	28060719
1581	Phosphorylation	DGEEEDVTVQE---- CCCCCCCCCCC----	28.88	28555341

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CE170_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CE170_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CE170_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PCY1A_HUMAN	PCYT1A	physical	26186194
SYNE2_HUMAN	SYNE2	physical	26186194
AKAP9_HUMAN	AKAP9	physical	26186194
KIFC3_HUMAN	KIFC3	physical	26186194
PSPC1_HUMAN	PSPC1	physical	26186194
PKD2_HUMAN	PKD2	physical	26186194
ASB7_HUMAN	ASB7	physical	26186194
NIN_HUMAN	NIN	physical	26186194
RUFY2_HUMAN	RUFY2	physical	26186194
C170B_HUMAN	CEP170B	physical	26186194
DUSTY_HUMAN	DSTYK	physical	26186194
DAPK3_HUMAN	DAPK3	physical	26186194
CP250_HUMAN	CEP250	physical	26186194
SPAG5_HUMAN	SPAG5	physical	26186194
MYOME_HUMAN	PDE4DIP	physical	26186194
SKAP_HUMAN	KNSTRN	physical	26186194
STX8_HUMAN	STX8	physical	26186194
COR1B_HUMAN	CORO1B	physical	26186194
BEGIN_HUMAN	BEGAIN	physical	26186194
RFWD3_HUMAN	RFWD3	physical	26186194
CCDC6_HUMAN	CCDC6	physical	26186194
TNKS1_HUMAN	TNKS	physical	26186194
MS18A_HUMAN	MIS18A	physical	26186194
VTI1B_HUMAN	VTI1B	physical	26186194
SNAPN_HUMAN	SNAPIN	physical	26186194
VAMP8_HUMAN	VAMP8	physical	26186194
AGFG1_HUMAN	AGFG1	physical	26638075
ARHG2_HUMAN	ARHGEF2	physical	26638075
ASCC3_HUMAN	ASCC3	physical	26638075
CP131_HUMAN	CEP131	physical	26638075
CAMP1_HUMAN	CAMSAP1	physical	26638075
CBL_HUMAN	CBL	physical	26638075
C2D1A_HUMAN	CC2D1A	physical	26638075
CCNB1_HUMAN	CCNB1	physical	26638075
CKAP2_HUMAN	CKAP2	physical	26638075
CRKL_HUMAN	CRKL	physical	26638075
KC1A_HUMAN	CSNK1A1	physical	26638075
DCLK1_HUMAN	DCLK1	physical	26638075
DCTN1_HUMAN	DCTN1	physical	26638075
FA83D_HUMAN	FAM83D	physical	26638075
HAUS3_HUMAN	HAUS3	physical	26638075
HAUS8_HUMAN	HAUS8	physical	26638075
IFT74_HUMAN	IFT74	physical	26638075
C170B_HUMAN	CEP170B	physical	26638075
KIF2A_HUMAN	KIF2A	physical	26638075
KIF2C_HUMAN	KIF2C	physical	26638075
KLHL9_HUMAN	KLHL9	physical	26638075
NCK1_HUMAN	NCK1	physical	26638075
PCM1_HUMAN	PCM1	physical	26638075
SHC1_HUMAN	SHC1	physical	26638075
TRIP6_HUMAN	TRIP6	physical	26638075
TTK_HUMAN	TTK	physical	26638075
UN45A_HUMAN	UNC45A	physical	26638075
WDR62_HUMAN	WDR62	physical	26638075
1433F_HUMAN	YWHAH	physical	26638075
ARP2_HUMAN	ACTR2	physical	26638075
ARRB2_HUMAN	ARRB2	physical	26638075
KCC2D_HUMAN	CAMK2D	physical	26638075
CC138_HUMAN	CCDC138	physical	26638075
CCD77_HUMAN	CCDC77	physical	26638075
CSK22_HUMAN	CSNK2A2	physical	26638075
DRG2_HUMAN	DRG2	physical	26638075
GOPC_HUMAN	GOPC	physical	26638075
GPX4_HUMAN	GPX4	physical	26638075
GRB2_HUMAN	GRB2	physical	26638075
GTSE1_HUMAN	GTSE1	physical	26638075
HAUS6_HUMAN	HAUS6	physical	26638075
HMMR_HUMAN	HMMR	physical	26638075
H1BP3_HUMAN	HS1BP3	physical	26638075
LASP1_HUMAN	LASP1	physical	26638075
LIMD1_HUMAN	LIMD1	physical	26638075
LUZP1_HUMAN	LUZP1	physical	26638075
MA7D1_HUMAN	MAP7D1	physical	26638075
MA7D3_HUMAN	MAP7D3	physical	26638075
MARE1_HUMAN	MAPRE1	physical	26638075
M21D2_HUMAN	MB21D2	physical	26638075
MS18A_HUMAN	MIS18A	physical	26638075
MTAP_HUMAN	MTAP	physical	26638075
MTMR6_HUMAN	MTMR6	physical	26638075
MTPN_HUMAN	MTPN	physical	26638075
SYNC_HUMAN	NARS	physical	26638075
NCK2_HUMAN	NCK2	physical	26638075
NEBL_HUMAN	NEBL	physical	26638075
NECP2_HUMAN	NECAP2	physical	26638075
NEDD1_HUMAN	NEDD1	physical	26638075
NDK7_HUMAN	NME7	physical	26638075
OCRL_HUMAN	OCRL	physical	26638075
PEA15_HUMAN	PEA15	physical	26638075
PPR21_HUMAN	PPP1R21	physical	26638075
RIR2_HUMAN	RRM2	physical	26638075
SDCB1_HUMAN	SDCBP	physical	26638075
SETD7_HUMAN	SETD7	physical	26638075
SKA1_HUMAN	SKA1	physical	26638075
SKA3_HUMAN	SKA3	physical	26638075
SLAI2_HUMAN	SLAIN2	physical	26638075
SMAP2_HUMAN	SMAP2	physical	26638075
SNX17_HUMAN	SNX17	physical	26638075
SPAG5_HUMAN	SPAG5	physical	26638075
SGT1_HUMAN	SUGT1	physical	26638075
TCHP_HUMAN	TCHP	physical	26638075
TYB10_HUMAN	TMSB10	physical	26638075
TXND9_HUMAN	TXNDC9	physical	26638075
RENT1_HUMAN	UPF1	physical	26638075
WRP73_HUMAN	WRAP73	physical	26638075
XIAP_HUMAN	XIAP	physical	26638075
ZC21A_HUMAN	ZC2HC1A	physical	26638075
FAP20_HUMAN	C1orf86	physical	26638075
DAPK3_HUMAN	DAPK3	physical	28514442
NIN_HUMAN	NIN	physical	28514442
SYNE2_HUMAN	SYNE2	physical	28514442
ASB7_HUMAN	ASB7	physical	28514442
PCY1A_HUMAN	PCYT1A	physical	28514442
RUFY2_HUMAN	RUFY2	physical	28514442
RFWD3_HUMAN	RFWD3	physical	28514442
C170B_HUMAN	CEP170B	physical	28514442
BEGIN_HUMAN	BEGAIN	physical	28514442
KIFC3_HUMAN	KIFC3	physical	28514442
SNAPN_HUMAN	SNAPIN	physical	28514442
MS18A_HUMAN	MIS18A	physical	28514442
AKAP9_HUMAN	AKAP9	physical	28514442
VAMP8_HUMAN	VAMP8	physical	28514442
MYOME_HUMAN	PDE4DIP	physical	28514442
VTI1B_HUMAN	VTI1B	physical	28514442
STX8_HUMAN	STX8	physical	28514442
CP250_HUMAN	CEP250	physical	28514442
SPAG5_HUMAN	SPAG5	physical	28514442
PKD2_HUMAN	PKD2	physical	28514442
DUSTY_HUMAN	DSTYK	physical	28514442
TNKS1_HUMAN	TNKS	physical	28514442
VPS53_HUMAN	VPS53	physical	28514442
COR1B_HUMAN	CORO1B	physical	28514442
CSK21_HUMAN	CSNK2A1	physical	27173435

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1112; SER-1160; SER-1165AND SER-1270, AND MASS SPECTROMETRY.
PubMed: 19690332

"Large-scale proteomics analysis of the human kinome.";
Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.;
Mol. Cell. Proteomics 8:1751-1764(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1112 AND SER-1165, ANDMASS SPECTROMETRY.
PubMed: 19369195

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-628; SER-630; SER-636AND SER-1112, AND MASS SPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-354; SER-356; SER-359;THR-501; TYR-502; THR-628; SER-633; SER-636; SER-838; SER-930;THR-937; SER-958; SER-1112; SER-1160; SER-1165; SER-1251; SER-1521;SER-1522; SER-1529 AND THR-1533, AND MASS SPECTROMETRY.
PubMed: 18669648

"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis.";
Wang B., Malik R., Nigg E.A., Korner R.;
Anal. Chem. 80:9526-9533(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-168; SER-636; SER-1079AND SER-1112, AND MASS SPECTROMETRY.
PubMed: 19007248

"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage.";
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.;
Science 316:1160-1166(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-630; SER-633 ANDSER-636, AND MASS SPECTROMETRY.
PubMed: 17525332

"Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry.";
Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.;
Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-566; SER-580; SER-667;SER-1160 AND SER-1165, AND MASS SPECTROMETRY.
PubMed: 17287340

"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1079, AND MASSSPECTROMETRY.
PubMed: 17924679

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-356; SER-359; THR-377;SER-838; SER-879; SER-1112 AND SER-1260, AND MASS SPECTROMETRY.
PubMed: 17081983

"Global phosphoproteome of HT-29 human colon adenocarcinoma cells.";
Kim J.-E., Tannenbaum S.R., White F.M.;
J. Proteome Res. 4:1339-1346(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1160, AND MASSSPECTROMETRY.
PubMed: 16083285