| UniProt ID | SYNE2_HUMAN | |
|---|---|---|
| UniProt AC | Q8WXH0 | |
| Protein Name | Nesprin-2 | |
| Gene Name | SYNE2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 6885 | |
| Subcellular Localization |
Nucleus outer membrane Single-pass type IV membrane protein Cytoplasmic side . Sarcoplasmic reticulum membrane Single-pass type IV membrane protein . Cell membrane Single-pass membrane protein . Cytoplasm, cytoskeleton. Mitochondrion. Nucleus, nuc |
|
| Protein Description | Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. May be involved in nucleus-centrosome attachment. During interkinetic nuclear migration (INM) at G2 phase and nuclear migration in neural progenitors its LINC complex association with SUN1/2 and probable association with cytoplasmic dynein-dynactin motor complexes functions to pull the nucleus toward the centrosome; SYNE1 and SYNE2 may act redundantly. During INM at G1 phase mediates respective LINC complex association with kinesin to push the nucleus away from the centrosome. Involved in nuclear migration in retinal photoreceptor progenitors. Required for centrosome migration to the apical cell surface during early ciliogenesis.. | |
| Protein Sequence | MASSPELPTEDEQGSWGIDDLHISLQAEQEDTQKKAFTCWINSQLARHTSPSVISDLFTDIKKGHVLLDLLEVLSGQQLPRDKGSNTFQCRINIEHALTFLRNRSIKLINIHVTDIIDGNPSIILGLIWTIILHFHIEKLAQTLSCNYNQPSLDDVSVVDSSPASSPPAKKCSKVQARWQMSARKALLLWAQEQCATYESVNVTDFKSSWRNGMAFLAIIHALRPDLIDMKSVKHRSNKDNLREAFRIAEQELKIPRLLEPEDVDVVDPDEKSIMTYVAQFLQYSKDAPGTGEEAQGKVKDAMGWLTLQKEKLQKLLKDSENDTYFKKYNSLLSFMESFNEEKKSFLDVLSIKRDLDELDKDHLQLREAWDGLDHQINAWKIKLNYALPPPLHQTEAWLQEVEELMDEDLSASQDHSQAVTLIQEKMTLFKSLMDRFEHHSNILLTFENKDENHLPLVPPNKLEEMKRRINNILEKKFILLLEFHYYKCLVLGLVDEVKSKLDIWNIKYGSRESVELLLEDWHKFIEEKEFLARLDTSFQKCGEIYKNLAGECQNINKQYMMVKSDVCMYRKNIYNVKSTLQKVLACWATYVENLRLLRACFEETKKEEIKEVPFETLAQWNLEHATLNEAGNFLVEVSNDVVGSSISKELRRLNKRWRKLVSKTQLEMNLPLMIKKQDQPTFDNSGNILSKEEKATVEFSTDMSVELPENYNQNIKAGEKHEKENEEFTGQLKVAKDVEKLIGQVEIWEAEAKSVLDQDDVDTSMEESLKHLIAKGSMFDELMARSEDMLQMDIQNISSQESFQHVLTTGLQAKIQEAKEKVQINVVKLIAALKNLTDVSPDLDIRLKMEESQKELESYMMRAQQLLGQRESPGELISKHKEALIISNTKSLAKYLKAVEELKNNVTEDIKMSLEEKSRDVCAKWESLHHELSLYVQQLKIDIEKGKLSDNILKLEKQINKEKKLIRRGRTKGLIKEHEACFSEEGCLYQLNHHMEVLRELCEELPSQKSQQEVKRLLKDYEQKIERLLKCASEIHMTLQPTAGGTSKNEGTITTSENRGGDPHSEAPFAKSDNQPSTEKAMEPTMKFSLASVLRPLQEESIMEKDYSASINSLLERYDTYRDILEHHLQNNKFRITSDFSSEEDRSSSCLQAKLTDLQVIKNETDARWKEFEIISLKLENHVNDIKKPFVIKERDTLKERERELQMTLNTRMESLETALRLVLPVEKASLLLCGSDLPLHKMAIQGFHLIDADRIYQHLRNIQDSIAKQIEICNRLEEPGNFVLKELHPFDLHAMQNIILKYKTQFEGMNHRVQRSEDTLKALEDFLASLRTAKLSAEPVTDLSASDTQVAQENTLTVKNKEGEIHLMKDKAKHLDKCLKMLDMSFKDAERGDDTSCENLLDAFSIKLSETHGYGVQEEFTEENKLLEACIFKNNELLKNIQDVQSQISKIGLKDPTVPAVKHRKKSLIRLDKVLDEYEEEKRHLQEMANSLPHFKDGREKTVNQQCQNTVVLWENTKALVTECLEQCGRVLELLKQYQNFKSILTTLIQKEESVISLQASYMGKENLKKRIAEIEIVKEEFNEHLEVVDKINQVCKNLQFYLNKMKTFEEPPFEKEANIIVDRWLDINEKTEDYYENLGRALALWDKLFNLKNVIDEWTEKALQKMELHQLTEEDRERLKEELQVHEQKTSEFSRRVAEIQFLLQSSEIPLELQVMESSILNKMEHVQKCLTGESNCHALSGSTAELREDLDQAKTQIGMTESLLKALSPSDSLEIFTKLEEIQQQILQQKHSMILLENQIGCLTPELSELKKQYESVSDLFNTKKSVLQDHFSKLLNDQCKNFNDWFSNIKVNLKECFESSETKKSVEQKLQKLSDFLTLEGRNSKIKQVDSVLKHVKKHLPKAHVKELISWLVGQEFELEKMESICQARAKELEDSLQQLLRLQDDHRNLRKWLTNQEEKWKGMEEPGEKTELFCQALARKREQFESVAQLNNSLKEYGFTEEEEIIMEATCLMDRYQTLLRQLSEIEEEDKLLPTEDQSFNDLAHDVIHWIKEIKESLMVLNSSEGKMPLEERIQKIKEIILLKPEGDARIETIMKQAESSEAPLVQKTLTDISNQWDNTLHLASTYLSHQEKLLLEGEKYLQSKEDLRLMLIELKKKQEAGFALQHGLQEKKAQLKIYKKFLKKAQDLTSLLKELKSQGNYLLECTKNPSFSEEPWLEIKHLHESLLQQLQDSVQNLDGHVREHDSYQVCVTDLNTTLDNFSKEFVSFSDKPVDQIAVEEKLQKLQELENRLSLQDGTLKKILALAKSVKQNTSSVGQKIIKDDIKSLQCKQKDLENRLASAKQEMECCLNSILKSKRSTEKKGKFTLPGREKQATSDVQESTQESAAVEKLEEDWEINKDSAVEMAMSKQLSLNAQESMKNTEDERKVNELQNQPLELDTMLRNEQLEEIEKLYTQLEAKKAAIKPLEQTECLNKTETGALVLHNIGYSAQHLDNLLQALITLKKNKESQYCVLRDFQEYLAAVESSMKALLTDKESLKVGPLDSVTYLDKIKKFIASIEKEKDSLGNLKIKWENLSNHVTDMDKKLLESQIKQLEHGWEQVEQQIQKKYSQQVVEYDEFTTLMNKVQDTEISLQQQQQHLQLRLKSPEERAGNQSMIALTTDLQATKHGFSVLKGQAELQMKRIWGEKEKKNLEDGINNLKKQWETLEPLHLEAENQIKKCDIRNKMKETILWAKNLLGELNPSIPLLPDDILSQIRKCKVTHDGILARQQSVESLAEEVKDKVPSLTTYEGSDLNNTLEDLRNQYQMLVLKSTQRSQQLEFKLEERSNFFAIIRKFQLMVQESETLIIPRVETAATEAELKHHHVTLEASQKELQEIDSGISTHLQELTNIYEELNVFERLFLEDQLKNLKIRTNRIQRFIQNTCNEVEHKIKFCRQFHEKTSALQEEADSIQRNELLLNQEVNKGVKEEIYNLKDRLTAIKCCILQVLKLKKVFDYIGLNWDFSQLDQLQTQVFEKEKELEEKIKQLDTFEEEHGKYQALLSKMRAIDLQIKKMTEVVLKAPDSSPESRRLNAQILSQRIEKAKCLCDEIIKKLNENKTFDDSFKEKEILQIKLNAEENDKLYKVLQNMVLELSPKELDEKNCQDKLETSLHVLNQIKSQLQQPLLINLEIKHIQNEKDNCEAFQEQVWAEMCSIKAVTAIEKQREENSSEASDVETKLREFEDLQMQLNTSIDLRTNVLNDAYENLTRYKEAVTRAVESITSLEAIIIPYRVDVGNPEESLEMPLRKQEELESTVAHIQDLTEKLGMISSPEAKLQLQYTLQELVSKNSAMKEAFKAQETEAERYLENYKCYRKMEEDIYTNLSKMETVLGQSMSSLPLSYREALERLEQSKALVSNLISTKEELMKLRQILRLLRLRCTENDGICLLKIVSALWEKWLSLLEAAKEWEMWCEELKQEWKFVSEEIEREAIILDNLQEELPEISKTKEAATTEELSELLDCLCQYGENVEKQQLLLTLLLQRIRSIQNVPESSGAVETVPAFQEITSMKERCNKLLQKVQKNKELVQTEIQERHSFTKEIIALKNFFQQTTTSFQNMAFQDHPEKSEQFEELQSILKKGKLTFENIMEKLRIKYSEMYTIVPAEIESQVEECRKALEDIDEKISNEVLKSSPSYAMRRKIEEINNGLHNVEKMLQQKSKNIEKAQEIQKKMWDELDLWHSKLNELDSEVQDIVEQDPGQAQEWMDNLMIPFQQYQQVSQRAECRTSQLNKATVKMEEYSDLLKSTEAWIENTSHLLANPADYDSLRTLSHHASTVQMALEDSEQKHNLLHSIFMDLEDLSIIFETDELTQSIQELSNQVTALQQKIMESLPQIQRMADDVVAIESEVKSMEKRVSKIKTILLSKEIFDFSPEEHLKHGEVILENIRPMKKTIAEIVSYQVELRLPQTGMKPLPVFQRTNQLLQDIKLLENVTQEQNELLKVVIKQTNEWDEEIENLKQILNNYSAQFSLEHMSPDQADKLPQLQGEIERMEKQILSLNQRKEDLLVDLKATVLNLHQHLKQEQEGVERDRLPAVTSEEGGVAERDASERKLNRRGSMSYLAAVEEEVEESSVKSDNGDEKAEPSPQSWSSLWKHDKDMEEDRASSSSGTIVQEAYGKISTSDNSMAQILTPDSLNTEQGPECSLRPNQTEEGTTPPIEADTLDSSDAQGGLEPRVEKTRPEPTEVLHACKTQVAELELWLQQANVAVEPETLNADMQQVLEQQLVGCQAMLTEIEHKVAFLLETCKDQGLGDNGATQHEAEALSLKLKTVKCNLEKVQMMLQEKHSEDQHPTILKKSSEPEHQEALQPVNLSELESIVTERPQFSRQKDFQQQQVLELKPMEQKDFIKFIEFNAKKMWPQYCQHDNDTTQESSASNQASSPENDVPDSILSPQGQNGDKWQYLHHELSSKIKLPLPQLVEPQVSTNMGILPSVTMYNFRYPTTEELKTYTTQLEDLRQEASNLQTQENMTEEAYINLDKKLFELFLTLSQCLSSVEEMLEMPRLYREDGSGQQVHYETLALELKKLYLALSDKKGDLLKAMTWPGENTNLLLECFDNLQVCLEHTQAAAVCRSKSLKAGLDYNRSYQNEIKRLYHQLIKSKTSLQQSLNEISGQSVAEQLQKADAYTVELENAESRVAKLRDEGERLHLPYALLQEVYKLEDVLDSMWGMLRARYTELSSPFVTESQQDALLQGMVELVKIGKEKLAHGHLKQTKSKVALQAQIENHKVFFQKLVADMLLIQAYSAKILPSLLQNRETFWAEQVTEVKILEEKSRQCGMKLQSLLQKWEEFDENYASLEKDLEILISTLPSVSLVEETEERLVERISFYQQIKRNIGGKHARLYQTLNEGKQLVASVSCPELEGQIAKLEEQWLSLNKKIDHELHRLQALLKHLLSYNRDSDQLTKWLESSQHTLNYWKEQSLNVSQDLDTIRSNINNFFEFSKEVDEKSSLKTAVISIGNQLLHLKETDTATLRASLAQFEQKWTMLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMNNVEHQTSDEDSVHSPSSASQVKHLLQKHKEFRMEMDYKQWIVDFVNQSLLQLSTCDVESKRYERTEFAEHLGEMNRQWHRVHGMLNRKIQHLEQLLESITESENKIQILNNWLEAQEERLKTLQKPESVISVQKLLLDCQDIENQLAIKSKALDELKQSYLTLESGAVPLLEDTASRIDELFQKRSSVLTQVNQLKTSMQSVLQEWKIYDQLYDEVNMMTIRFWYCMEHSKPVVLSLETLRCQVENLQSLQDEAESSEGSWEKLQEVIGKLKGLCPSVAEIIEEKCQNTHKRWTQVNQAIADQLQKAQSLLQLWKAYSNAHGEAAARLKQQEAKFQQLANISMSGNNLAEILPPALQDIKELQHDVQKTKEAFLQNSSVLDRLPQPAESSTHMLLPGPLHSLQRAAYLEKMLLVKANEFEFVLSQFKDFGVRLESLKGLIMHEEENLDRLHQQEKENPDSFLNHVLALTAQSPDIEHLNEVSLKLPLSDVAVKTLQNMNRQWIRATATALERCSELQGIGLNEKFLYCCEKWIQLLEKIEEALKVDVANSLPELLEQQKTYKMLEAEVSINQTIADSYVTQSLQLLDTTEIENRPEFITEFSKLTDRWQNAVQGVRQRKGDVDGLVRQWQDFTTSVENLFRFLTDTSHLLSAVKGQERFSLYQTRSLIHELKNKEIHFQRRRTTCALTLEAGEKLLLTTDLKTKESVGRRISQLQDSWKDMEPQLAEMIKQFQSTVETWDQCEKKIKELKSRLQVLKAQSEDPLPELHEDLHNEKELIKELEQSLASWTQNLKELQTMKADLTRHVLVEDVMVLKEQIEHLHRQWEDLCLRVAIRKQEIEDRLNTWVVFNEKNKELCAWLVQMENKVLQTADISIEEMIEKLQKDCMEEINLFSENKLQLKQMGDQLIKASNKSRAAEIDDKLNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSKPVVYDVCDDQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLYTSAKEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASRLKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHFSESDADDKMRQLNGFQQEITLNTNKIDQLIVFGEQLIQKSEPLDAVLIEDELEELHRYCQEVFGRVSRFHRRLTSCTPGLEDEKEASENETDMEDPREIQTDSWRKRGESEEPSSPQSLCHLVAPGHERSGCETPVSVDSIPLEWDHTGDVGGSSSHEEDEEGPYYSALSGKSISDGHSWHVPDSPSCPEHHYKQMEGDRNVPPVPPASSTPYKPPYGKLLLPPGTDGGKEGPRVLNGNPQQEDGGLAGITEQQSGAFDRWEMIQAQELHNKLKIKQNLQQLNSDISAITTWLKKTEAELEMLKMAKPPSDIQEIELRVKRLQEILKAFDTYKALVVSVNVSSKEFLQTESPESTELQSRLRQLSLLWEAAQGAVDSWRGGLRQSLMQCQDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALLECRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLKQLREQVSQDLMALQGTQNPASPLPSFDEVDSGDQPPATSVPAPRAKQFRAVRTTEGEEETESRVPGSTRPQRSFLSRVVRAALPLQLLLLLLLLLACLLPSSEEDYSCTQANNFARSFYPMLRYTNGPPPT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MASSPELPTE -----CCCCCCCCCC | 59.28 | 27251275 | |
| 3 (in isoform 2) | Phosphorylation | - | 59.28 | 27251275 | |
| 4 | Phosphorylation | ----MASSPELPTED ----CCCCCCCCCCC | 29.47 | 27251275 | |
| 9 | Phosphorylation | ASSPELPTEDEQGSW CCCCCCCCCCCCCCC | 69.56 | 27251275 | |
| 15 | Phosphorylation | PTEDEQGSWGIDDLH CCCCCCCCCCCCCEE | 23.09 | 27251275 | |
| 18 (in isoform 5) | Phosphorylation | - | 2.79 | - | |
| 22 (in isoform 5) | Phosphorylation | - | 18.00 | - | |
| 23 (in isoform 5) | Phosphorylation | - | 5.97 | - | |
| 26 (in isoform 5) | Phosphorylation | - | 35.74 | - | |
| 49 | Phosphorylation | NSQLARHTSPSVISD HHHHHHCCCHHHHHH | 36.46 | - | |
| 50 | Phosphorylation | SQLARHTSPSVISDL HHHHHCCCHHHHHHH | 14.73 | - | |
| 52 | Phosphorylation | LARHTSPSVISDLFT HHHCCCHHHHHHHHC | 31.67 | - | |
| 59 | Phosphorylation | SVISDLFTDIKKGHV HHHHHHHCCHHCCCH | 44.08 | - | |
| 62 | Acetylation | SDLFTDIKKGHVLLD HHHHCCHHCCCHHHH | 56.35 | 25953088 | |
| 85 | Phosphorylation | QLPRDKGSNTFQCRI CCCCCCCCCCEEEEE | 38.14 | 25278378 | |
| 87 | Phosphorylation | PRDKGSNTFQCRINI CCCCCCCCEEEEEEH | 19.44 | 25278378 | |
| 143 | Phosphorylation | HIEKLAQTLSCNYNQ HHHHHHHHHCCCCCC | 18.29 | 23090842 | |
| 145 | Phosphorylation | EKLAQTLSCNYNQPS HHHHHHHCCCCCCCC | 12.05 | 23090842 | |
| 148 | Phosphorylation | AQTLSCNYNQPSLDD HHHHCCCCCCCCCCC | 21.36 | 23090842 | |
| 152 | Phosphorylation | SCNYNQPSLDDVSVV CCCCCCCCCCCCEEE | 34.37 | 23090842 | |
| 157 | Phosphorylation | QPSLDDVSVVDSSPA CCCCCCCEEECCCCC | 24.34 | 23663014 | |
| 161 | Phosphorylation | DDVSVVDSSPASSPP CCCEEECCCCCCCCC | 26.98 | 23663014 | |
| 162 | Phosphorylation | DVSVVDSSPASSPPA CCEEECCCCCCCCCC | 21.74 | 23663014 | |
| 165 | Phosphorylation | VVDSSPASSPPAKKC EECCCCCCCCCCHHC | 46.92 | 23663014 | |
| 166 | Phosphorylation | VDSSPASSPPAKKCS ECCCCCCCCCCHHCC | 36.69 | 30278072 | |
| 166 (in isoform 2) | Phosphorylation | - | 36.69 | 27251275 | |
| 190 (in isoform 6) | Phosphorylation | - | 8.89 | 27174698 | |
| 197 (in isoform 6) | Phosphorylation | - | 35.13 | 27174698 | |
| 197 (in isoform 7) | Phosphorylation | - | 35.13 | 28634298 | |
| 199 (in isoform 6) | Phosphorylation | - | 43.80 | 27174698 | |
| 204 (in isoform 7) | Phosphorylation | - | 30.43 | 28634298 | |
| 206 (in isoform 7) | Phosphorylation | - | 6.37 | 28634298 | |
| 207 (in isoform 7) | Phosphorylation | - | 46.52 | 28634298 | |
| 208 (in isoform 7) | Phosphorylation | - | 34.82 | 28634298 | |
| 210 (in isoform 7) | Phosphorylation | - | 12.59 | 28634298 | |
| 219 (in isoform 7) | Phosphorylation | - | 2.29 | 26552605 | |
| 224 | Dimethylation | LAIIHALRPDLIDMK HHHHHHHCHHHCCCC | 24.38 | - | |
| 224 | Methylation | LAIIHALRPDLIDMK HHHHHHHCHHHCCCC | 24.38 | 24390291 | |
| 239 (in isoform 4) | Phosphorylation | - | 49.60 | - | |
| 254 | Ubiquitination | RIAEQELKIPRLLEP HHHHHHHCCCCCCCC | 50.33 | - | |
| 262 (in isoform 4) | Phosphorylation | - | 62.38 | - | |
| 266 (in isoform 4) | Phosphorylation | - | 5.45 | - | |
| 267 (in isoform 4) | Phosphorylation | - | 8.38 | - | |
| 270 (in isoform 4) | Phosphorylation | - | 72.06 | - | |
| 273 | Phosphorylation | VVDPDEKSIMTYVAQ CCCCCHHHHHHHHHH | 18.62 | 20068231 | |
| 276 | Phosphorylation | PDEKSIMTYVAQFLQ CCHHHHHHHHHHHHH | 17.11 | 20068231 | |
| 276 (in isoform 2) | Phosphorylation | - | 17.11 | 27251275 | |
| 277 | Phosphorylation | DEKSIMTYVAQFLQY CHHHHHHHHHHHHHH | 4.03 | 20068231 | |
| 316 (in isoform 5) | Phosphorylation | - | 4.66 | 27174698 | |
| 318 | Ubiquitination | EKLQKLLKDSENDTY HHHHHHHCCCCCCHH | 70.42 | - | |
| 323 (in isoform 5) | Phosphorylation | - | 38.44 | 27174698 | |
| 325 (in isoform 5) | Phosphorylation | - | 19.10 | 27174698 | |
| 361 | Ubiquitination | RDLDELDKDHLQLRE CCHHHHCHHHHHHHH | 60.72 | - | |
| 508 | Acetylation | KLDIWNIKYGSRESV HHCCCCCCCCCHHHH | 40.10 | 18585291 | |
| 529 | Ubiquitination | WHKFIEEKEFLARLD HHHHHHHHHHHHHHC | 40.76 | - | |
| 546 | Phosphorylation | FQKCGEIYKNLAGEC HHHHHHHHHHHHHHH | 6.90 | 22461510 | |
| 558 | Ubiquitination | GECQNINKQYMMVKS HHHCCCCHHHHEEHH | 38.72 | - | |
| 560 | Phosphorylation | CQNINKQYMMVKSDV HCCCCHHHHEEHHCE | 6.70 | 22461510 | |
| 570 | Phosphorylation | VKSDVCMYRKNIYNV EHHCEEHHHCCCCCH | 17.20 | - | |
| 572 | Malonylation | SDVCMYRKNIYNVKS HCEEHHHCCCCCHHH | 30.15 | 26320211 | |
| 575 | Phosphorylation | CMYRKNIYNVKSTLQ EHHHCCCCCHHHHHH | 24.24 | - | |
| 578 | Ubiquitination | RKNIYNVKSTLQKVL HCCCCCHHHHHHHHH | 33.80 | - | |
| 663 | Phosphorylation | KRWRKLVSKTQLEMN HHHHHHHHHHHHHHC | 40.18 | - | |
| 665 | Phosphorylation | WRKLVSKTQLEMNLP HHHHHHHHHHHHCCC | 30.77 | - | |
| 676 | Methylation | MNLPLMIKKQDQPTF HCCCEEEECCCCCCC | 30.34 | - | |
| 676 (in isoform 2) | Ubiquitination | - | 30.34 | - | |
| 677 (in isoform 2) | Ubiquitination | - | 48.45 | - | |
| 686 | Phosphorylation | DQPTFDNSGNILSKE CCCCCCCCCCCCCHH | 34.75 | 28555341 | |
| 692 (in isoform 2) | Ubiquitination | - | 67.46 | - | |
| 705 | Phosphorylation | VEFSTDMSVELPENY EEEECCCCEECCCCC | 18.43 | - | |
| 764 | Phosphorylation | LDQDDVDTSMEESLK CCCCCCCCCHHHHHH | 29.80 | 25159151 | |
| 765 | Phosphorylation | DQDDVDTSMEESLKH CCCCCCCCHHHHHHH | 21.52 | 25159151 | |
| 769 | Phosphorylation | VDTSMEESLKHLIAK CCCCHHHHHHHHHHH | 29.43 | 22210691 | |
| 771 | Ubiquitination | TSMEESLKHLIAKGS CCHHHHHHHHHHHCC | 45.72 | - | |
| 799 | Phosphorylation | QMDIQNISSQESFQH HCHHHCCCCHHHHHH | 33.25 | 30576142 | |
| 820 (in isoform 2) | Ubiquitination | - | 58.26 | - | |
| 838 | Phosphorylation | IAALKNLTDVSPDLD HHHHCCCCCCCCCHH | 43.69 | 26657352 | |
| 841 | Phosphorylation | LKNLTDVSPDLDIRL HCCCCCCCCCHHHHH | 18.59 | 30266825 | |
| 841 (in isoform 2) | Phosphorylation | - | 18.59 | 27251275 | |
| 853 | Phosphorylation | IRLKMEESQKELESY HHHCCHHHHHHHHHH | 32.99 | 23663014 | |
| 859 | Phosphorylation | ESQKELESYMMRAQQ HHHHHHHHHHHHHHH | 30.84 | 23663014 | |
| 860 | Phosphorylation | SQKELESYMMRAQQL HHHHHHHHHHHHHHH | 5.88 | 23663014 | |
| 873 | Phosphorylation | QLLGQRESPGELISK HHHCCCCCCCCHHHH | 40.15 | 30266825 | |
| 873 (in isoform 2) | Phosphorylation | - | 40.15 | 24719451 | |
| 879 | Phosphorylation | ESPGELISKHKEALI CCCCCHHHHHHHEEE | 41.13 | 30266825 | |
| 882 | Acetylation | GELISKHKEALIISN CCHHHHHHHEEEECC | 48.71 | 7972675 | |
| 928 | Phosphorylation | DVCAKWESLHHELSL HHHHHHHHHHHHHHH | 31.71 | 20873877 | |
| 934 | Phosphorylation | ESLHHELSLYVQQLK HHHHHHHHHHHHHHC | 18.05 | 20873877 | |
| 936 | Phosphorylation | LHHELSLYVQQLKID HHHHHHHHHHHHCCH | 7.88 | 20873877 | |
| 948 | Acetylation | KIDIEKGKLSDNILK CCHHHCCCCCHHHHH | 56.75 | 25953088 | |
| 955 | Acetylation | KLSDNILKLEKQINK CCCHHHHHHHHHHHH | 51.29 | 19608861 | |
| 955 (in isoform 2) | Acetylation | - | 51.29 | - | |
| 958 (in isoform 2) | Ubiquitination | - | 67.90 | - | |
| 1008 | O-linked_Glycosylation | ELCEELPSQKSQQEV HHHHHCCCCHHHHHH | 63.97 | 30379171 | |
| 1010 | Ubiquitination | CEELPSQKSQQEVKR HHHCCCCHHHHHHHH | 55.35 | - | |
| 1090 | O-linked_Glycosylation | MEPTMKFSLASVLRP CCCCHHHHHHHHHHH | 19.94 | 30379171 | |
| 1102 | O-linked_Glycosylation | LRPLQEESIMEKDYS HHHHCHHHHHCCCCH | 26.87 | 30379171 | |
| 1111 | Phosphorylation | MEKDYSASINSLLER HCCCCHHHHHHHHHH | 19.16 | 27251275 | |
| 1111 (in isoform 2) | Phosphorylation | - | 19.16 | 27251275 | |
| 1138 | Phosphorylation | QNNKFRITSDFSSEE HCCCEEECCCCCCCC | 20.28 | - | |
| 1139 | Phosphorylation | NNKFRITSDFSSEED CCCEEECCCCCCCCC | 34.00 | - | |
| 1166 | Phosphorylation | LQVIKNETDARWKEF CHHHHCCCCCCHHEE | 44.33 | 23403867 | |
| 1177 | Phosphorylation | WKEFEIISLKLENHV HHEEEEEEEEEHHHC | 25.72 | 24719451 | |
| 1216 | Phosphorylation | TLNTRMESLETALRL HHHHHHHHHHHHHHH | 23.35 | 20068231 | |
| 1219 | Phosphorylation | TRMESLETALRLVLP HHHHHHHHHHHHHHC | 35.96 | 20068231 | |
| 1331 | Phosphorylation | ALEDFLASLRTAKLS HHHHHHHHHHHCCCC | 22.11 | 20068231 | |
| 1331 (in isoform 2) | Phosphorylation | - | 22.11 | - | |
| 1334 | Phosphorylation | DFLASLRTAKLSAEP HHHHHHHHCCCCCCC | 33.18 | - | |
| 1336 | Ubiquitination | LASLRTAKLSAEPVT HHHHHHCCCCCCCCC | 42.22 | - | |
| 1338 | Phosphorylation | SLRTAKLSAEPVTDL HHHHCCCCCCCCCCC | 29.85 | 28270605 | |
| 1343 | Phosphorylation | KLSAEPVTDLSASDT CCCCCCCCCCCCCCC | 41.77 | 28270605 | |
| 1346 | Phosphorylation | AEPVTDLSASDTQVA CCCCCCCCCCCCCCC | 28.65 | 28270605 | |
| 1348 | Phosphorylation | PVTDLSASDTQVAQE CCCCCCCCCCCCCHH | 37.50 | 28270605 | |
| 1350 | Phosphorylation | TDLSASDTQVAQENT CCCCCCCCCCCHHCE | 23.58 | 28270605 | |
| 1357 | Phosphorylation | TQVAQENTLTVKNKE CCCCHHCEEEEECCC | 24.05 | 28270605 | |
| 1359 | Phosphorylation | VAQENTLTVKNKEGE CCHHCEEEEECCCCC | 27.65 | 28270605 | |
| 1407 | Phosphorylation | ENLLDAFSIKLSETH HHHHHHHCCCCHHHC | 22.12 | 24719451 | |
| 1416 (in isoform 2) | Phosphorylation | - | 13.40 | 27642862 | |
| 1452 | Acetylation | DVQSQISKIGLKDPT HHHHHHHHCCCCCCC | 42.28 | 12430095 | |
| 1456 | Acetylation | QISKIGLKDPTVPAV HHHHCCCCCCCCCCH | 57.35 | 12430105 | |
| 1469 | Phosphorylation | AVKHRKKSLIRLDKV CHHCCHHHHHHHHHH | 31.87 | 28355574 | |
| 1469 (in isoform 2) | Phosphorylation | - | 31.87 | 24719451 | |
| 1475 | Acetylation | KSLIRLDKVLDEYEE HHHHHHHHHHHHHHH | 49.65 | 25953088 | |
| 1480 | Phosphorylation | LDKVLDEYEEEKRHL HHHHHHHHHHHHHHH | 28.45 | - | |
| 1538 | Acetylation | GRVLELLKQYQNFKS HHHHHHHHHHHCHHH | 60.63 | 25953088 | |
| 1556 | Phosphorylation | TLIQKEESVISLQAS HHHHHHHHHHHHHHH | 26.33 | 26074081 | |
| 1559 | Phosphorylation | QKEESVISLQASYMG HHHHHHHHHHHHHCC | 16.57 | 26074081 | |
| 1563 | Phosphorylation | SVISLQASYMGKENL HHHHHHHHHCCHHHH | 11.59 | 26074081 | |
| 1564 | Phosphorylation | VISLQASYMGKENLK HHHHHHHHCCHHHHH | 16.95 | 26074081 | |
| 1610 | Phosphorylation | FYLNKMKTFEEPPFE HHHHHCCCCCCCCCC | 32.55 | - | |
| 1618 | Ubiquitination | FEEPPFEKEANIIVD CCCCCCCHHHCEEEE | 63.61 | - | |
| 1634 | Phosphorylation | WLDINEKTEDYYENL EECCCHHCHHHHHHH | 28.10 | 20068231 | |
| 1637 | Phosphorylation | INEKTEDYYENLGRA CCHHCHHHHHHHHHH | 13.37 | 20068231 | |
| 1638 | Phosphorylation | NEKTEDYYENLGRAL CHHCHHHHHHHHHHH | 15.63 | 20068231 | |
| 1638 (in isoform 2) | Phosphorylation | - | 15.63 | - | |
| 1664 | Ubiquitination | VIDEWTEKALQKMEL HHHHHHHHHHHHHHH | 47.20 | - | |
| 1722 | Phosphorylation | ELQVMESSILNKMEH HHHHHHHHHHHHHHH | 20.14 | 24719451 | |
| 1738 | Phosphorylation | QKCLTGESNCHALSG HHHHHCCCHHHHHCC | 46.21 | 23312004 | |
| 1744 | Phosphorylation | ESNCHALSGSTAELR CCHHHHHCCCHHHHH | 31.33 | 23312004 | |
| 1744 (in isoform 2) | Phosphorylation | - | 31.33 | 27251275 | |
| 1746 | Phosphorylation | NCHALSGSTAELRED HHHHHCCCHHHHHHH | 22.52 | 23312004 | |
| 1747 | Phosphorylation | CHALSGSTAELREDL HHHHCCCHHHHHHHH | 27.90 | 23312004 | |
| 1758 | Acetylation | REDLDQAKTQIGMTE HHHHHHHHHHHCCCH | 35.02 | 20167786 | |
| 1766 | Phosphorylation | TQIGMTESLLKALSP HHHCCCHHHHHHCCC | 29.81 | 24719451 | |
| 1772 | Phosphorylation | ESLLKALSPSDSLEI HHHHHHCCCHHHHHH | 27.50 | 21815630 | |
| 1772 (in isoform 2) | Phosphorylation | - | 27.50 | 24719451 | |
| 1774 | Phosphorylation | LLKALSPSDSLEIFT HHHHCCCHHHHHHHH | 36.13 | 27732954 | |
| 1776 | Phosphorylation | KALSPSDSLEIFTKL HHCCCHHHHHHHHHH | 32.04 | 27732954 | |
| 1816 | Ubiquitination | PELSELKKQYESVSD HHHHHHHHHHHCHHH | 71.40 | - | |
| 1820 | Phosphorylation | ELKKQYESVSDLFNT HHHHHHHCHHHHHHC | 23.22 | 27251275 | |
| 1822 | Phosphorylation | KKQYESVSDLFNTKK HHHHHCHHHHHHCCH | 37.56 | 27251275 | |
| 1822 (in isoform 2) | Phosphorylation | - | 37.56 | 27251275 | |
| 1827 | Phosphorylation | SVSDLFNTKKSVLQD CHHHHHHCCHHHHHH | 32.30 | 24247654 | |
| 1829 | Ubiquitination | SDLFNTKKSVLQDHF HHHHHCCHHHHHHHH | 43.70 | - | |
| 1859 | Ubiquitination | SNIKVNLKECFESSE HHCEEHHHHHHHCCC | 47.43 | - | |
| 1877 | Ubiquitination | SVEQKLQKLSDFLTL HHHHHHHHHHHHHHH | 61.47 | - | |
| 1892 | Ubiquitination | EGRNSKIKQVDSVLK CCCCHHHHHHHHHHH | 48.26 | - | |
| 1896 | Phosphorylation | SKIKQVDSVLKHVKK HHHHHHHHHHHHHHH | 30.41 | 28857561 | |
| 1936 | Ubiquitination | SICQARAKELEDSLQ HHHHHHHHHHHHHHH | 58.22 | - | |
| 1957 | Ubiquitination | DDHRNLRKWLTNQEE HHHHHHHHHHHCHHH | 50.12 | - | |
| 1976 | Phosphorylation | MEEPGEKTELFCQAL CCCCCHHHHHHHHHH | 33.35 | 20068231 | |
| 1976 (in isoform 2) | Phosphorylation | - | 33.35 | - | |
| 1986 | Ubiquitination | FCQALARKREQFESV HHHHHHHCHHHHHHH | 55.47 | - | |
| 2030 | Phosphorylation | QTLLRQLSEIEEEDK HHHHHHHHHHHHHHC | 28.34 | 28348404 | |
| 2041 | Phosphorylation | EEDKLLPTEDQSFND HHHCCCCCCCCCHHH | 52.76 | 22199227 | |
| 2045 | Phosphorylation | LLPTEDQSFNDLAHD CCCCCCCCHHHHHHH | 38.04 | 22199227 | |
| 2063 | Phosphorylation | WIKEIKESLMVLNSS HHHHHHHHHCCCCCC | 19.43 | 22210691 | |
| 2069 | Phosphorylation | ESLMVLNSSEGKMPL HHHCCCCCCCCCCCH | 26.13 | 22210691 | |
| 2070 | Phosphorylation | SLMVLNSSEGKMPLE HHCCCCCCCCCCCHH | 49.66 | 22210691 | |
| 2090 | Ubiquitination | IKEIILLKPEGDARI HHHHEEECCCCCHHH | 37.26 | - | |
| 2114 | Ubiquitination | SEAPLVQKTLTDISN CCCCCCHHHHHHHHH | 37.71 | - | |
| 2115 | Phosphorylation | EAPLVQKTLTDISNQ CCCCCHHHHHHHHHH | 20.14 | - | |
| 2117 | Phosphorylation | PLVQKTLTDISNQWD CCCHHHHHHHHHHHH | 36.20 | - | |
| 2164 | Ubiquitination | MLIELKKKQEAGFAL HHHHHHHHHHHHHHH | 52.35 | - | |
| 2178 | Ubiquitination | LQHGLQEKKAQLKIY HHHCCHHHHHHHHHH | 40.21 | - | |
| 2191 | Ubiquitination | IYKKFLKKAQDLTSL HHHHHHHHHHHHHHH | 54.12 | - | |
| 2197 | Phosphorylation | KKAQDLTSLLKELKS HHHHHHHHHHHHHHH | 38.71 | 24719451 | |
| 2200 | Ubiquitination | QDLTSLLKELKSQGN HHHHHHHHHHHHCCC | 67.31 | - | |
| 2204 | Phosphorylation | SLLKELKSQGNYLLE HHHHHHHHCCCEEEE | 56.81 | 20860994 | |
| 2213 | Phosphorylation | GNYLLECTKNPSFSE CCEEEEECCCCCCCC | 25.20 | 20860994 | |
| 2214 | Ubiquitination | NYLLECTKNPSFSEE CEEEEECCCCCCCCC | 77.76 | - | |
| 2291 | Ubiquitination | AVEEKLQKLQELENR HHHHHHHHHHHHHHC | 63.67 | - | |
| 2300 | Phosphorylation | QELENRLSLQDGTLK HHHHHCCCCCHHHHH | 22.28 | - | |
| 2305 | Phosphorylation | RLSLQDGTLKKILAL CCCCCHHHHHHHHHH | 43.63 | 19664995 | |
| 2305 (in isoform 2) | Phosphorylation | - | 43.63 | 24719451 | |
| 2314 | Acetylation | KKILALAKSVKQNTS HHHHHHHHHHHHCCC | 57.54 | 25953088 | |
| 2314 | Ubiquitination | KKILALAKSVKQNTS HHHHHHHHHHHHCCC | 57.54 | - | |
| 2317 | Acetylation | LALAKSVKQNTSSVG HHHHHHHHHCCCCHH | 44.94 | 25953088 | |
| 2317 | Ubiquitination | LALAKSVKQNTSSVG HHHHHHHHHCCCCHH | 44.94 | - | |
| 2320 | Phosphorylation | AKSVKQNTSSVGQKI HHHHHHCCCCHHCHH | 21.64 | 25690035 | |
| 2321 | Phosphorylation | KSVKQNTSSVGQKII HHHHHCCCCHHCHHH | 30.49 | 25690035 | |
| 2322 | Phosphorylation | SVKQNTSSVGQKIIK HHHHCCCCHHCHHHH | 28.38 | 25690035 | |
| 2326 | Ubiquitination | NTSSVGQKIIKDDIK CCCCHHCHHHHHHHH | 40.23 | - | |
| 2329 | Malonylation | SVGQKIIKDDIKSLQ CHHCHHHHHHHHHCC | 53.47 | 26320211 | |
| 2333 | Ubiquitination | KIIKDDIKSLQCKQK HHHHHHHHHCCHHHH | 52.70 | - | |
| 2345 | Methylation | KQKDLENRLASAKQE HHHHHHHHHHHHHHH | 23.43 | 115918073 | |
| 2359 | Phosphorylation | EMECCLNSILKSKRS HHHHHHHHHHHHCCC | 19.15 | 24719451 | |
| 2374 | Phosphorylation | TEKKGKFTLPGREKQ CCCCCCCCCCCCCCC | 35.21 | - | |
| 2416 | Phosphorylation | SAVEMAMSKQLSLNA HHHHHHHHHHHCHHH | 14.01 | 29083192 | |
| 2420 | Phosphorylation | MAMSKQLSLNAQESM HHHHHHHCHHHHHHH | 19.65 | 30108239 | |
| 2420 (in isoform 2) | Phosphorylation | - | 19.65 | 27251275 | |
| 2435 | Ubiquitination | KNTEDERKVNELQNQ CCCHHHHHHHHHHCC | 47.57 | - | |
| 2460 | Ubiquitination | EQLEEIEKLYTQLEA HHHHHHHHHHHHHHH | 53.08 | - | |
| 2462 (in isoform 2) | Phosphorylation | - | 11.96 | 27642862 | |
| 2468 | Ubiquitination | LYTQLEAKKAAIKPL HHHHHHHHHHCCCCH | 33.30 | - | |
| 2469 | Ubiquitination | YTQLEAKKAAIKPLE HHHHHHHHHCCCCHH | 50.53 | - | |
| 2469 (in isoform 2) | Ubiquitination | - | 50.53 | - | |
| 2473 | Ubiquitination | EAKKAAIKPLEQTEC HHHHHCCCCHHHCCC | 38.53 | - | |
| 2478 | Phosphorylation | AIKPLEQTECLNKTE CCCCHHHCCCCCCCC | 21.20 | - | |
| 2515 | Ubiquitination | LITLKKNKESQYCVL HHHHHCCCCCCEEEE | 68.56 | - | |
| 2543 | Ubiquitination | MKALLTDKESLKVGP HHHHHCCHHHCCCCC | 43.92 | - | |
| 2547 | Ubiquitination | LTDKESLKVGPLDSV HCCHHHCCCCCCCCC | 55.19 | - | |
| 2559 | Ubiquitination | DSVTYLDKIKKFIAS CCCHHHHHHHHHHHH | 54.55 | - | |
| 2562 | Ubiquitination | TYLDKIKKFIASIEK HHHHHHHHHHHHHHH | 45.54 | - | |
| 2578 | Ubiquitination | KDSLGNLKIKWENLS HCCCCCCEEEEHHHH | 46.36 | - | |
| 2578 (in isoform 2) | Ubiquitination | - | 46.36 | - | |
| 2585 | Phosphorylation | KIKWENLSNHVTDMD EEEEHHHHHHCCHHH | 36.15 | 29083192 | |
| 2589 | Phosphorylation | ENLSNHVTDMDKKLL HHHHHHCCHHHHHHH | 20.32 | 29083192 | |
| 2601 | Ubiquitination | KLLESQIKQLEHGWE HHHHHHHHHHHHHHH | 40.99 | - | |
| 2616 | Ubiquitination | QVEQQIQKKYSQQVV HHHHHHHHHHHHHHH | 56.14 | - | |
| 2617 | Ubiquitination | VEQQIQKKYSQQVVE HHHHHHHHHHHHHHC | 33.49 | - | |
| 2655 | Phosphorylation | HLQLRLKSPEERAGN HHHHHCCCHHHHHCC | 41.98 | 24719451 | |
| 2655 (in isoform 2) | Phosphorylation | - | 41.98 | 24719451 | |
| 2664 | Phosphorylation | EERAGNQSMIALTTD HHHHCCCCEEEEECC | 19.02 | 22496350 | |
| 2669 | Phosphorylation | NQSMIALTTDLQATK CCCEEEEECCHHHHH | 14.83 | 20860994 | |
| 2670 | Phosphorylation | QSMIALTTDLQATKH CCEEEEECCHHHHHH | 35.25 | 24300666 | |
| 2675 | Phosphorylation | LTTDLQATKHGFSVL EECCHHHHHHCCCHH | 15.60 | 20860994 | |
| 2676 | Ubiquitination | TTDLQATKHGFSVLK ECCHHHHHHCCCHHH | 44.75 | - | |
| 2680 | Phosphorylation | QATKHGFSVLKGQAE HHHHHCCCHHHCCHH | 31.00 | 20860994 | |
| 2691 | Ubiquitination | GQAELQMKRIWGEKE CCHHHHHHHHHCHHH | 27.98 | - | |
| 2697 | Ubiquitination | MKRIWGEKEKKNLED HHHHHCHHHHHCHHH | 71.54 | - | |
| 2700 | Ubiquitination | IWGEKEKKNLEDGIN HHCHHHHHCHHHHHH | 68.78 | - | |
| 2710 | Ubiquitination | EDGINNLKKQWETLE HHHHHHHHHHHHHCC | 45.07 | - | |
| 2711 | Ubiquitination | DGINNLKKQWETLEP HHHHHHHHHHHHCCC | 64.90 | - | |
| 2728 | Ubiquitination | LEAENQIKKCDIRNK HHHHHCHHCCCHHHH | 37.27 | - | |
| 2739 | Phosphorylation | IRNKMKETILWAKNL HHHHHHHHHHHHHHH | 18.82 | 20860994 | |
| 2769 | Ubiquitination | LSQIRKCKVTHDGIL HHHHHCCCCCCCHHH | 53.88 | - | |
| 2781 | Phosphorylation | GILARQQSVESLAEE HHHHCHHHHHHHHHH | 21.36 | 23401153 | |
| 2781 (in isoform 2) | Phosphorylation | - | 21.36 | 24719451 | |
| 2784 | Phosphorylation | ARQQSVESLAEEVKD HCHHHHHHHHHHHHH | 30.62 | 30266825 | |
| 2821 | Ubiquitination | QYQMLVLKSTQRSQQ HHHHHHHHHCCHHHC | 43.93 | - | |
| 2934 | Phosphorylation | IQRFIQNTCNEVEHK HHHHHHHHHHHHHHH | 10.59 | 20068231 | |
| 2934 (in isoform 2) | Phosphorylation | - | 10.59 | - | |
| 2951 | Acetylation | FCRQFHEKTSALQEE HHHHHHHHHHHHHHH | 38.93 | 23954790 | |
| 2951 | Ubiquitination | FCRQFHEKTSALQEE HHHHHHHHHHHHHHH | 38.93 | - | |
| 2975 | Ubiquitination | LLNQEVNKGVKEEIY HHHHHHHHHHHHHHH | 70.97 | - | |
| 2978 | Ubiquitination | QEVNKGVKEEIYNLK HHHHHHHHHHHHCHH | 59.29 | - | |
| 2985 | Ubiquitination | KEEIYNLKDRLTAIK HHHHHCHHHHHHHHH | 36.84 | - | |
| 3036 | Ubiquitination | KELEEKIKQLDTFEE HHHHHHHHCHHCHHH | 56.74 | - | |
| 3040 | Phosphorylation | EKIKQLDTFEEEHGK HHHHCHHCHHHHHHH | 41.35 | 20068231 | |
| 3040 (in isoform 2) | Phosphorylation | - | 41.35 | - | |
| 3047 | Ubiquitination | TFEEEHGKYQALLSK CHHHHHHHHHHHHHH | 35.78 | - | |
| 3054 | Ubiquitination | KYQALLSKMRAIDLQ HHHHHHHHHHHHHHH | 32.16 | - | |
| 3066 | Phosphorylation | DLQIKKMTEVVLKAP HHHHHHCEEHHHHCC | 34.21 | - | |
| 3071 | Acetylation | KMTEVVLKAPDSSPE HCEEHHHHCCCCCHH | 46.38 | 7934609 | |
| 3071 | Ubiquitination | KMTEVVLKAPDSSPE HCEEHHHHCCCCCHH | 46.38 | - | |
| 3075 | Phosphorylation | VVLKAPDSSPESRRL HHHHCCCCCHHHHHH | 46.89 | 24719451 | |
| 3075 (in isoform 2) | Phosphorylation | - | 46.89 | 24719451 | |
| 3076 | Phosphorylation | VLKAPDSSPESRRLN HHHCCCCCHHHHHHH | 39.81 | - | |
| 3088 | Phosphorylation | RLNAQILSQRIEKAK HHHHHHHHHHHHHHH | 21.02 | 24719451 | |
| 3116 | Ubiquitination | KTFDDSFKEKEILQI CCCCCCCCHHHHEEE | 72.35 | - | |
| 3145 | Phosphorylation | QNMVLELSPKELDEK HHHHHHCCHHHHCCC | 25.26 | 29255136 | |
| 3145 (in isoform 2) | Phosphorylation | - | 25.26 | 24719451 | |
| 3157 | Ubiquitination | DEKNCQDKLETSLHV CCCCCHHHHHHHHHH | 23.50 | - | |
| 3183 | Ubiquitination | LLINLEIKHIQNEKD EEHHHHHHHCCCCCC | 25.86 | - | |
| 3220 | Phosphorylation | EKQREENSSEASDVE HHHHHHCCCCCCHHH | 32.60 | 25278378 | |
| 3221 | Phosphorylation | KQREENSSEASDVET HHHHHCCCCCCHHHH | 49.08 | 25278378 | |
| 3224 | Phosphorylation | EENSSEASDVETKLR HHCCCCCCHHHHHHH | 37.83 | 25278378 | |
| 3228 | Phosphorylation | SEASDVETKLREFED CCCCHHHHHHHHHHH | 34.92 | 25278378 | |
| 3229 | Ubiquitination | EASDVETKLREFEDL CCCHHHHHHHHHHHH | 31.85 | - | |
| 3255 | Phosphorylation | TNVLNDAYENLTRYK HHHHHHHHHHHHHHH | 14.28 | - | |
| 3299 (in isoform 2) | Ubiquitination | - | 70.51 | - | |
| 3321 | Phosphorylation | TEKLGMISSPEAKLQ HHHHCCCCCHHHHHH | 30.83 | - | |
| 3322 | Phosphorylation | EKLGMISSPEAKLQL HHHCCCCCHHHHHHH | 18.81 | - | |
| 3339 | Ubiquitination | TLQELVSKNSAMKEA HHHHHHHCCHHHHHH | 47.65 | - | |
| 3344 | Ubiquitination | VSKNSAMKEAFKAQE HHCCHHHHHHHHHHH | 45.68 | - | |
| 3362 | Ubiquitination | ERYLENYKCYRKMEE HHHHHHCHHHHHCHH | 36.05 | - | |
| 3364 | Phosphorylation | YLENYKCYRKMEEDI HHHHCHHHHHCHHHH | 14.76 | - | |
| 3372 | Phosphorylation | RKMEEDIYTNLSKME HHCHHHHHHCHHHHH | 11.25 | - | |
| 3380 | Phosphorylation | TNLSKMETVLGQSMS HCHHHHHHHHCCCCC | 19.96 | 20068231 | |
| 3408 | Phosphorylation | EQSKALVSNLISTKE HHHHHHHHHHCCCHH | 27.11 | 20068231 | |
| 3412 | Phosphorylation | ALVSNLISTKEELMK HHHHHHCCCHHHHHH | 36.27 | 24719451 | |
| 3414 (in isoform 2) | Ubiquitination | - | 42.26 | - | |
| 3497 | Ubiquitination | EELPEISKTKEAATT HHCCHHHCCCCCCCH | 70.09 | - | |
| 3537 | Phosphorylation | LLLQRIRSIQNVPES HHHHHHHHHCCCCCC | 26.59 | 22210691 | |
| 3550 | Phosphorylation | ESSGAVETVPAFQEI CCCCCCCCCHHHHHH | 25.78 | 22210691 | |
| 3558 | Phosphorylation | VPAFQEITSMKERCN CHHHHHHHHHHHHHH | 23.24 | 28787133 | |
| 3559 | Phosphorylation | PAFQEITSMKERCNK HHHHHHHHHHHHHHH | 33.25 | 22210691 | |
| 3575 | Acetylation | LQKVQKNKELVQTEI HHHHHHCHHHHHHHH | 60.50 | 26051181 | |
| 3587 | Phosphorylation | TEIQERHSFTKEIIA HHHHHHHCCHHHHHH | 40.61 | 24719451 | |
| 3626 | Phosphorylation | EQFEELQSILKKGKL HHHHHHHHHHHCCCC | 42.38 | 24719451 | |
| 3659 | Phosphorylation | IVPAEIESQVEECRK EECHHHHHHHHHHHH | 45.23 | - | |
| 3681 | Ubiquitination | KISNEVLKSSPSYAM HHHHHHHHCCCCHHH | 54.80 | - | |
| 3682 | Phosphorylation | ISNEVLKSSPSYAMR HHHHHHHCCCCHHHH | 43.23 | 24719451 | |
| 3682 (in isoform 2) | Phosphorylation | - | 43.23 | 24719451 | |
| 3683 | Phosphorylation | SNEVLKSSPSYAMRR HHHHHHCCCCHHHHH | 19.11 | 28122231 | |
| 3683 (in isoform 2) | Phosphorylation | - | 19.11 | 27251275 | |
| 3685 | Phosphorylation | EVLKSSPSYAMRRKI HHHHCCCCHHHHHHH | 27.72 | 28122231 | |
| 3691 | Ubiquitination | PSYAMRRKIEEINNG CCHHHHHHHHHHHHH | 44.07 | - | |
| 3710 | Phosphorylation | EKMLQQKSKNIEKAQ HHHHHHHCCCHHHHH | 26.96 | 29083192 | |
| 3732 | Phosphorylation | DELDLWHSKLNELDS HHHHHHHHHHHHHHH | 27.53 | 20068231 | |
| 3782 | Ubiquitination | CRTSQLNKATVKMEE HHHHHHHHHCCCHHH | 54.77 | - | |
| 3784 | Phosphorylation | TSQLNKATVKMEEYS HHHHHHHCCCHHHHH | 23.44 | 22964224 | |
| 3790 | Phosphorylation | ATVKMEEYSDLLKST HCCCHHHHHHHHHHH | 8.32 | 20068231 | |
| 3790 (in isoform 2) | Phosphorylation | - | 8.32 | 27642862 | |
| 3791 | Phosphorylation | TVKMEEYSDLLKSTE CCCHHHHHHHHHHHH | 25.68 | 20068231 | |
| 3796 | Phosphorylation | EYSDLLKSTEAWIEN HHHHHHHHHHHHHHC | 31.30 | - | |
| 3814 (in isoform 2) | Phosphorylation | - | 14.99 | 27642862 | |
| 3816 | Phosphorylation | ANPADYDSLRTLSHH CCCCCHHHHHHHHHH | 17.33 | - | |
| 3819 | Phosphorylation | ADYDSLRTLSHHAST CCHHHHHHHHHHHHH | 37.59 | 23312004 | |
| 3821 | Phosphorylation | YDSLRTLSHHASTVQ HHHHHHHHHHHHHHH | 16.77 | 23312004 | |
| 3825 | Phosphorylation | RTLSHHASTVQMALE HHHHHHHHHHHHHHC | 25.42 | 23312004 | |
| 3826 | Phosphorylation | TLSHHASTVQMALED HHHHHHHHHHHHHCC | 18.62 | 23312004 | |
| 3843 | Phosphorylation | QKHNLLHSIFMDLED HHHHHHHHHHCCHHH | 19.93 | - | |
| 3881 | Phosphorylation | LQQKIMESLPQIQRM HHHHHHHCCHHHHHH | 28.15 | - | |
| 3911 | Phosphorylation | KRVSKIKTILLSKEI HHHHHHHHHHHCCCH | 21.96 | - | |
| 3943 | Phosphorylation | NIRPMKKTIAEIVSY CCCCCCHHHHHHHCC | 21.65 | 28450419 | |
| 3949 | Phosphorylation | KTIAEIVSYQVELRL HHHHHHHCCCEEEEC | 18.60 | 28450419 | |
| 3949 (in isoform 2) | Phosphorylation | - | 18.60 | - | |
| 3950 | Phosphorylation | TIAEIVSYQVELRLP HHHHHHCCCEEEECC | 12.99 | 28450419 | |
| 3978 | Ubiquitination | NQLLQDIKLLENVTQ HHHHHHHHHHHCCCH | 56.14 | - | |
| 3984 | Phosphorylation | IKLLENVTQEQNELL HHHHHCCCHHHHHHH | 37.66 | - | |
| 3992 | Ubiquitination | QEQNELLKVVIKQTN HHHHHHHHHHHHHCC | 47.26 | - | |
| 3998 | Phosphorylation | LKVVIKQTNEWDEEI HHHHHHHCCCHHHHH | 30.06 | 29978859 | |
| 4025 | Phosphorylation | QFSLEHMSPDQADKL HHHHHCCCHHHHHCC | 27.51 | 25627689 | |
| 4053 | Ubiquitination | ILSLNQRKEDLLVDL HHHHHHCHHHHHHHH | 45.90 | - | |
| 4072 | Ubiquitination | LNLHQHLKQEQEGVE HHHHHHHHHHHCCCC | 50.06 | - | |
| 4099 | Phosphorylation | GVAERDASERKLNRR CCCCCCCCCHHCCCC | 42.07 | 28555341 | |
| 4108 | Phosphorylation | RKLNRRGSMSYLAAV HHCCCCCCHHHHHHH | 11.62 | 25159151 | |
| 4108 (in isoform 2) | Phosphorylation | - | 11.62 | 27251275 | |
| 4110 | Phosphorylation | LNRRGSMSYLAAVEE CCCCCCHHHHHHHHH | 20.77 | 30266825 | |
| 4110 (in isoform 2) | Phosphorylation | - | 20.77 | - | |
| 4111 | Phosphorylation | NRRGSMSYLAAVEEE CCCCCHHHHHHHHHH | 7.54 | 30278072 | |
| 4111 (in isoform 2) | Phosphorylation | - | 7.54 | - | |
| 4122 | Phosphorylation | VEEEVEESSVKSDNG HHHHHHHCCCCCCCC | 27.25 | 28176443 | |
| 4122 (in isoform 2) | Phosphorylation | - | 27.25 | 27251275 | |
| 4123 | Phosphorylation | EEEVEESSVKSDNGD HHHHHHCCCCCCCCC | 36.52 | 23663014 | |
| 4123 (in isoform 2) | Phosphorylation | - | 36.52 | 27251275 | |
| 4126 | Phosphorylation | VEESSVKSDNGDEKA HHHCCCCCCCCCCCC | 33.87 | 23663014 | |
| 4126 (in isoform 2) | Phosphorylation | - | 33.87 | 27251275 | |
| 4136 | Phosphorylation | GDEKAEPSPQSWSSL CCCCCCCCCCCHHHH | 27.38 | 30266825 | |
| 4136 (in isoform 2) | Phosphorylation | - | 27.38 | 24719451 | |
| 4139 | Phosphorylation | KAEPSPQSWSSLWKH CCCCCCCCHHHHHHC | 32.10 | 30266825 | |
| 4139 (in isoform 2) | Phosphorylation | - | 32.10 | 27251275 | |
| 4141 | Phosphorylation | EPSPQSWSSLWKHDK CCCCCCHHHHHHCCC | 22.32 | 30266825 | |
| 4142 | Phosphorylation | PSPQSWSSLWKHDKD CCCCCHHHHHHCCCC | 31.80 | 30266825 | |
| 4156 | Phosphorylation | DMEEDRASSSSGTIV CCHHHHHCCCCCCHH | 31.48 | 30278072 | |
| 4156 (in isoform 2) | Phosphorylation | - | 31.48 | 24719451 | |
| 4157 | Phosphorylation | MEEDRASSSSGTIVQ CHHHHHCCCCCCHHH | 27.78 | 30278072 | |
| 4158 | Phosphorylation | EEDRASSSSGTIVQE HHHHHCCCCCCHHHH | 30.23 | 21955146 | |
| 4158 (in isoform 2) | Phosphorylation | - | 30.23 | 27251275 | |
| 4159 | Phosphorylation | EDRASSSSGTIVQEA HHHHCCCCCCHHHHH | 41.73 | 30278072 | |
| 4159 (in isoform 2) | Phosphorylation | - | 41.73 | 24719451 | |
| 4161 | Phosphorylation | RASSSSGTIVQEAYG HHCCCCCCHHHHHHC | 21.66 | 30278072 | |
| 4161 (in isoform 2) | Phosphorylation | - | 21.66 | 27251275 | |
| 4167 | Phosphorylation | GTIVQEAYGKISTSD CCHHHHHHCEECCCC | 20.42 | 20873877 | |
| 4182 | Phosphorylation | NSMAQILTPDSLNTE CCCCCCCCCCCCCCC | 27.03 | - | |
| 4201 | Phosphorylation | CSLRPNQTEEGTTPP CCCCCCCCCCCCCCC | 42.52 | 28111955 | |
| 4205 | Phosphorylation | PNQTEEGTTPPIEAD CCCCCCCCCCCCCCC | 39.13 | 28111955 | |
| 4206 | Phosphorylation | NQTEEGTTPPIEADT CCCCCCCCCCCCCCC | 37.61 | 28111955 | |
| 4213 | Phosphorylation | TPPIEADTLDSSDAQ CCCCCCCCCCCCCCC | 39.24 | 28111955 | |
| 4216 | Phosphorylation | IEADTLDSSDAQGGL CCCCCCCCCCCCCCC | 32.98 | 28111955 | |
| 4217 | Phosphorylation | EADTLDSSDAQGGLE CCCCCCCCCCCCCCC | 36.31 | 28111955 | |
| 4230 | Phosphorylation | LEPRVEKTRPEPTEV CCCCCEECCCCCHHH | 37.64 | 20068231 | |
| 4235 | Phosphorylation | EKTRPEPTEVLHACK EECCCCCHHHHHHHH | 36.74 | 20068231 | |
| 4284 | Phosphorylation | VGCQAMLTEIEHKVA HHHHHHHHHHHHHHH | 23.10 | - | |
| 4316 | Phosphorylation | QHEAEALSLKLKTVK HHHHHHHHCHHHHCC | 30.42 | 24719451 | |
| 4328 | Acetylation | TVKCNLEKVQMMLQE HCCCCHHHHHHHHHH | 40.72 | 25953088 | |
| 4338 | Phosphorylation | MMLQEKHSEDQHPTI HHHHHHCCCCCCCCC | 54.67 | 29083192 | |
| 4344 | Phosphorylation | HSEDQHPTILKKSSE CCCCCCCCCCCCCCC | 36.50 | 29083192 | |
| 4348 | Ubiquitination | QHPTILKKSSEPEHQ CCCCCCCCCCCHHHH | 56.63 | - | |
| 4349 | Phosphorylation | HPTILKKSSEPEHQE CCCCCCCCCCHHHHH | 38.04 | 30108239 | |
| 4350 | Phosphorylation | PTILKKSSEPEHQEA CCCCCCCCCHHHHHH | 67.08 | 30108239 | |
| 4368 | Phosphorylation | VNLSELESIVTERPQ CCHHHHHHHHCCCCC | 34.68 | 24173317 | |
| 4407 | Acetylation | KFIEFNAKKMWPQYC HHHHHHHHHHCCCCC | 44.24 | 25953088 | |
| 4492 | Phosphorylation | VTMYNFRYPTTEELK CEEEECCCCCHHHHH | 10.78 | 21406692 | |
| 4494 | Phosphorylation | MYNFRYPTTEELKTY EEECCCCCHHHHHHH | 37.59 | 22210691 | |
| 4494 (in isoform 2) | Phosphorylation | - | 37.59 | 21406692 | |
| 4495 | Phosphorylation | YNFRYPTTEELKTYT EECCCCCHHHHHHHH | 23.98 | 20068231 | |
| 4495 (in isoform 2) | Phosphorylation | - | 23.98 | - | |
| 4545 | Phosphorylation | LTLSQCLSSVEEMLE HHHHHHHHHHHHHHH | 39.71 | 22210691 | |
| 4546 | Phosphorylation | TLSQCLSSVEEMLEM HHHHHHHHHHHHHHC | 22.16 | 22210691 | |
| 4557 | Phosphorylation | MLEMPRLYREDGSGQ HHHCCCHHCCCCCCC | 17.15 | 22210691 | |
| 4629 | Ubiquitination | VCRSKSLKAGLDYNR HHHCCCHHHCCCCCH | 47.72 | - | |
| 4651 | Acetylation | RLYHQLIKSKTSLQQ HHHHHHHHCCCHHHH | 55.26 | 25953088 | |
| 4718 | Phosphorylation | KLEDVLDSMWGMLRA CHHHHHHHHHHHHHH | 16.57 | 26425664 | |
| 4732 | Phosphorylation | ARYTELSSPFVTESQ HHCHHCCCCCCCHHH | 34.67 | - | |
| 4780 | Ubiquitination | QAQIENHKVFFQKLV HHHHHCCHHHHHHHH | 52.93 | - | |
| 4796 | Phosphorylation | DMLLIQAYSAKILPS HHHHHHHHHHCHHHH | 7.87 | - | |
| 4797 | Phosphorylation | MLLIQAYSAKILPSL HHHHHHHHHCHHHHH | 26.54 | - | |
| 4803 | Phosphorylation | YSAKILPSLLQNRET HHHCHHHHHHHCCCC | 37.96 | 21406692 | |
| 4803 (in isoform 2) | Phosphorylation | - | 37.96 | 21406692 | |
| 4832 | Acetylation | KSRQCGMKLQSLLQK HHHHHCCHHHHHHHH | 28.76 | 25953088 | |
| 4839 | Ubiquitination | KLQSLLQKWEEFDEN HHHHHHHHHHHHHHH | 57.45 | - | |
| 4847 | Phosphorylation | WEEFDENYASLEKDL HHHHHHHHHCHHHHH | 8.77 | - | |
| 4849 | Phosphorylation | EFDENYASLEKDLEI HHHHHHHCHHHHHHH | 27.05 | 20068231 | |
| 4881 | Phosphorylation | LVERISFYQQIKRNI HHHHHHHHHHHHHHC | 7.85 | 20068231 | |
| 4891 | Acetylation | IKRNIGGKHARLYQT HHHHCCCHHHHHHHH | 28.95 | 12422283 | |
| 4930 | Ubiquitination | EQWLSLNKKIDHELH HHHHHHHHHHHHHHH | 57.30 | - | |
| 5027 | Methylation | ETDTATLRASLAQFE CCCHHHHHHHHHHHH | 20.13 | 24388077 | |
| 5038 | Phosphorylation | AQFEQKWTMLITQLP HHHHHHHHHHHHHCH | 14.77 | 20068231 | |
| 5038 (in isoform 2) | Phosphorylation | - | 14.77 | - | |
| 5042 | Phosphorylation | QKWTMLITQLPDIQE HHHHHHHHHCHHHHH | 21.79 | 20068231 | |
| 5042 (in isoform 2) | Phosphorylation | - | 21.79 | - | |
| 5066 | Phosphorylation | LPSRKAITEMISWMN CCCHHHHHHHHHHHH | 25.10 | 26307563 | |
| 5070 | Phosphorylation | KAITEMISWMNNVEH HHHHHHHHHHHCCCC | 20.97 | 26307563 | |
| 5079 | Phosphorylation | MNNVEHQTSDEDSVH HHCCCCCCCCCCCCC | 39.80 | 26307563 | |
| 5080 | Phosphorylation | NNVEHQTSDEDSVHS HCCCCCCCCCCCCCC | 32.22 | 26307563 | |
| 5084 | Phosphorylation | HQTSDEDSVHSPSSA CCCCCCCCCCCCCCH | 21.49 | 26307563 | |
| 5087 | Phosphorylation | SDEDSVHSPSSASQV CCCCCCCCCCCHHHH | 25.07 | 26471730 | |
| 5087 (in isoform 2) | Phosphorylation | - | 25.07 | 24719451 | |
| 5089 | Phosphorylation | EDSVHSPSSASQVKH CCCCCCCCCHHHHHH | 41.36 | 26307563 | |
| 5090 | Phosphorylation | DSVHSPSSASQVKHL CCCCCCCCHHHHHHH | 35.01 | 26307563 | |
| 5092 | Phosphorylation | VHSPSSASQVKHLLQ CCCCCCHHHHHHHHH | 37.14 | 26307563 | |
| 5100 | Ubiquitination | QVKHLLQKHKEFRME HHHHHHHHCHHHHHH | 57.52 | - | |
| 5171 | Phosphorylation | HLEQLLESITESENK HHHHHHHHHCCCCHH | 34.48 | 21406692 | |
| 5171 (in isoform 2) | Phosphorylation | - | 34.48 | 21406692 | |
| 5173 | Phosphorylation | EQLLESITESENKIQ HHHHHHHCCCCHHHH | 42.62 | 21406692 | |
| 5175 | Phosphorylation | LLESITESENKIQIL HHHHHCCCCHHHHHH | 37.51 | 21406692 | |
| 5222 | Ubiquitination | IENQLAIKSKALDEL HHHHHHHHHHHHHHH | 40.05 | - | |
| 5230 (in isoform 2) | Ubiquitination | - | 34.84 | - | |
| 5257 | Ubiquitination | RIDELFQKRSSVLTQ HHHHHHHHHHHHHHH | 47.08 | - | |
| 5259 | Phosphorylation | DELFQKRSSVLTQVN HHHHHHHHHHHHHHH | 31.66 | - | |
| 5282 | Phosphorylation | VLQEWKIYDQLYDEV HHHHHHHHHHHHHHH | 8.23 | 20068231 | |
| 5282 (in isoform 2) | Phosphorylation | - | 8.23 | - | |
| 5286 | Phosphorylation | WKIYDQLYDEVNMMT HHHHHHHHHHHHHHH | 12.39 | 20068231 | |
| 5293 | Phosphorylation | YDEVNMMTIRFWYCM HHHHHHHHHHHHHHH | 9.76 | 20068231 | |
| 5293 (in isoform 2) | Phosphorylation | - | 9.76 | - | |
| 5364 | Ubiquitination | EKCQNTHKRWTQVNQ HHHHHHHHHHHHHHH | 47.82 | - | |
| 5566 | Acetylation | PLSDVAVKTLQNMNR CHHHHHHHHHHHHCH | 33.51 | 26051181 | |
| 5587 | Phosphorylation | ATALERCSELQGIGL HHHHHHHHHCCCCCC | 47.79 | 20068231 | |
| 5632 | Ubiquitination | PELLEQQKTYKMLEA HHHHHHHHHHHHHHH | 54.22 | - | |
| 5719 | Phosphorylation | LFRFLTDTSHLLSAV HHHHHHCHHHHHHHH | 16.89 | 15302935 | |
| 5735 | Phosphorylation | GQERFSLYQTRSLIH CCCCCCHHHHHHHHH | 13.46 | - | |
| 5739 | Phosphorylation | FSLYQTRSLIHELKN CCHHHHHHHHHHHHC | 34.75 | 20873877 | |
| 5756 | Phosphorylation | IHFQRRRTTCALTLE CCHHHCCCCEEEEEC | 25.15 | 23312004 | |
| 5757 | Phosphorylation | HFQRRRTTCALTLEA CHHHCCCCEEEEECC | 8.25 | 23312004 | |
| 5761 | Phosphorylation | RRTTCALTLEAGEKL CCCCEEEEECCCCEE | 12.20 | 23312004 | |
| 5785 | Phosphorylation | ESVGRRISQLQDSWK HHHHHHHHHHHHHHH | 24.03 | 28348404 | |
| 5984 | Phosphorylation | GDQLIKASNKSRAAE HHHHHHHCCHHCHHH | 39.53 | 23403867 | |
| 5995 | 2-Hydroxyisobutyrylation | RAAEIDDKLNKINDR CHHHHHHHHHHHHHH | 50.65 | - | |
| 5998 | Acetylation | EIDDKLNKINDRWQH HHHHHHHHHHHHHHH | 54.01 | 25953088 | |
| 6029 | Ubiquitination | AFIQQLDKNMSNLRT HHHHHHCHHHHHHHH | 64.24 | - | |
| 6043 | Phosphorylation | TWLARIESELSKPVV HHHHHHHHHHCCCEE | 41.27 | 21406692 | |
| 6043 (in isoform 2) | Phosphorylation | - | 41.27 | 21406692 | |
| 6173 | Ubiquitination | EVLYTSAKEELKRFE HHEECCHHHHHHHHH | 52.03 | - | |
| 6209 | Phosphorylation | RLARENRTDTASRLK HHHHHCCCCHHHHHH | 49.65 | 20068231 | |
| 6211 | Phosphorylation | ARENRTDTASRLKQM HHHCCCCHHHHHHHH | 26.39 | 25599653 | |
| 6213 | Phosphorylation | ENRTDTASRLKQMVH HCCCCHHHHHHHHHH | 39.99 | 20068231 | |
| 6234 | O-linked_Glycosylation | DNLQRRVTAVLRRLR HHHHHHHHHHHHHHH | 14.83 | 30379171 | |
| 6314 | Phosphorylation | GEQLIQKSEPLDAVL HHHHHHCCCCCCEEE | 28.24 | 24719451 | |
| 6314 (in isoform 2) | Phosphorylation | - | 28.24 | 24719451 | |
| 6348 | Phosphorylation | SRFHRRLTSCTPGLE HHHHHHHHCCCCCCC | 21.68 | 23927012 | |
| 6349 | Phosphorylation | RFHRRLTSCTPGLED HHHHHHHCCCCCCCC | 22.15 | 23927012 | |
| 6349 (in isoform 2) | Phosphorylation | - | 22.15 | 27251275 | |
| 6351 | Phosphorylation | HRRLTSCTPGLEDEK HHHHHCCCCCCCCHH | 21.84 | 23927012 | |
| 6351 (in isoform 2) | Phosphorylation | - | 21.84 | 27251275 | |
| 6361 | Phosphorylation | LEDEKEASENETDME CCCHHHHCCCCCCCC | 41.88 | 29255136 | |
| 6361 (in isoform 2) | Phosphorylation | - | 41.88 | 21406692 | |
| 6365 | Phosphorylation | KEASENETDMEDPRE HHHCCCCCCCCCHHH | 52.83 | 30266825 | |
| 6375 | Phosphorylation | EDPREIQTDSWRKRG CCHHHHHCCHHHHCC | 37.35 | 23403867 | |
| 6377 | Phosphorylation | PREIQTDSWRKRGES HHHHHCCHHHHCCCC | 31.97 | 21815630 | |
| 6384 | Phosphorylation | SWRKRGESEEPSSPQ HHHHCCCCCCCCCCC | 50.51 | 23927012 | |
| 6384 (in isoform 2) | Phosphorylation | - | 50.51 | - | |
| 6388 | Phosphorylation | RGESEEPSSPQSLCH CCCCCCCCCCCHHHH | 58.91 | 23927012 | |
| 6388 (in isoform 2) | Phosphorylation | - | 58.91 | 24719451 | |
| 6389 | Phosphorylation | GESEEPSSPQSLCHL CCCCCCCCCCHHHHH | 37.36 | 23927012 | |
| 6389 (in isoform 2) | Phosphorylation | - | 37.36 | 27251275 | |
| 6392 | Phosphorylation | EEPSSPQSLCHLVAP CCCCCCCHHHHHHCC | 36.03 | 23927012 | |
| 6392 (in isoform 2) | Phosphorylation | - | 36.03 | - | |
| 6404 | Phosphorylation | VAPGHERSGCETPVS HCCCCCCCCCCCCCC | 44.82 | 24144214 | |
| 6408 | Phosphorylation | HERSGCETPVSVDSI CCCCCCCCCCCCCCC | 32.82 | 24144214 | |
| 6411 | Phosphorylation | SGCETPVSVDSIPLE CCCCCCCCCCCCCCC | 22.78 | 24144214 | |
| 6414 | Phosphorylation | ETPVSVDSIPLEWDH CCCCCCCCCCCCCCC | 24.77 | 30576142 | |
| 6422 | Phosphorylation | IPLEWDHTGDVGGSS CCCCCCCCCCCCCCC | 32.38 | 23927012 | |
| 6428 | Phosphorylation | HTGDVGGSSSHEEDE CCCCCCCCCCCCCCC | 23.80 | 30576142 | |
| 6429 | Phosphorylation | TGDVGGSSSHEEDEE CCCCCCCCCCCCCCC | 38.70 | 23927012 | |
| 6430 | Phosphorylation | GDVGGSSSHEEDEEG CCCCCCCCCCCCCCC | 36.29 | 23927012 | |
| 6439 | Phosphorylation | EEDEEGPYYSALSGK CCCCCCCCEECCCCC | 22.40 | 23927012 | |
| 6440 | Phosphorylation | EDEEGPYYSALSGKS CCCCCCCEECCCCCC | 7.21 | 27174698 | |
| 6441 | Phosphorylation | DEEGPYYSALSGKSI CCCCCCEECCCCCCC | 19.52 | 27174698 | |
| 6444 | Phosphorylation | GPYYSALSGKSISDG CCCEECCCCCCCCCC | 43.84 | 27174698 | |
| 6447 | Phosphorylation | YSALSGKSISDGHSW EECCCCCCCCCCCCC | 30.74 | 23663014 | |
| 6449 | Phosphorylation | ALSGKSISDGHSWHV CCCCCCCCCCCCCCC | 44.63 | 23663014 | |
| 6453 | Phosphorylation | KSISDGHSWHVPDSP CCCCCCCCCCCCCCC | 25.14 | 23663014 | |
| 6459 | Phosphorylation | HSWHVPDSPSCPEHH CCCCCCCCCCCCHHH | 16.79 | 23927012 | |
| 6461 | Phosphorylation | WHVPDSPSCPEHHYK CCCCCCCCCCHHHHH | 46.38 | 23663014 | |
| 6467 | Phosphorylation | PSCPEHHYKQMEGDR CCCCHHHHHHCCCCC | 12.57 | 23663014 | |
| 6470 (in isoform 2) | Phosphorylation | - | 5.63 | 27251275 | |
| 6476 (in isoform 2) | Phosphorylation | - | 6.21 | 24719451 | |
| 6482 (in isoform 2) | Phosphorylation | - | 15.28 | 24719451 | |
| 6484 | O-linked_Glycosylation | PPVPPASSTPYKPPY CCCCCCCCCCCCCCC | 35.19 | 30379171 | |
| 6485 | O-linked_Glycosylation | PVPPASSTPYKPPYG CCCCCCCCCCCCCCC | 28.30 | 30379171 | |
| 6500 | Phosphorylation | KLLLPPGTDGGKEGP CCCCCCCCCCCCCCC | 36.93 | 21815630 | |
| 6546 | Ubiquitination | QAQELHNKLKIKQNL HHHHHHHHHHHHHHH | 40.17 | - | |
| 6558 | Phosphorylation | QNLQQLNSDISAITT HHHHHHCCCHHHHHH | 44.93 | 30622161 | |
| 6561 | Phosphorylation | QQLNSDISAITTWLK HHHCCCHHHHHHHHH | 20.71 | 30622161 | |
| 6564 | Phosphorylation | NSDISAITTWLKKTE CCCHHHHHHHHHHHH | 16.19 | 30622161 | |
| 6565 | Phosphorylation | SDISAITTWLKKTEA CCHHHHHHHHHHHHH | 23.76 | 30622161 | |
| 6616 | Phosphorylation | LVVSVNVSSKEFLQT EEEEEECCCHHHHCC | 30.41 | 20886841 | |
| 6623 | Phosphorylation | SSKEFLQTESPESTE CCHHHHCCCCCCHHH | 40.35 | 22199227 | |
| 6625 | Phosphorylation | KEFLQTESPESTELQ HHHHCCCCCCHHHHH | 37.04 | 21815630 | |
| 6628 | Phosphorylation | LQTESPESTELQSRL HCCCCCCHHHHHHHH | 30.48 | 22199227 | |
| 6693 | Ubiquitination | KAHVTDPKADPRALL HCCCCCCCCCHHHHH | 69.13 | - | |
| 6751 | Acetylation | EKVHVIEKKLKQLRE HHHHHHHHHHHHHHH | 52.89 | 25953088 | |
| 6775 | Phosphorylation | QGTQNPASPLPSFDE CCCCCCCCCCCCCCC | 28.38 | 26074081 | |
| 6779 | Phosphorylation | NPASPLPSFDEVDSG CCCCCCCCCCCCCCC | 53.68 | 26074081 | |
| 6807 | Phosphorylation | KQFRAVRTTEGEEET HHCEEEECCCCCCCC | 23.70 | 26437602 | |
| 6808 | Phosphorylation | QFRAVRTTEGEEETE HCEEEECCCCCCCCC | 31.28 | 29083192 | |
| 6814 | Phosphorylation | TTEGEEETESRVPGS CCCCCCCCCCCCCCC | 42.41 | 29083192 | |
| 6816 | Phosphorylation | EGEEETESRVPGSTR CCCCCCCCCCCCCCC | 46.10 | 29083192 | |
| 6830 | Phosphorylation | RPQRSFLSRVVRAAL CCCHHHHHHHHHHHH | 22.48 | 24719451 | |
| 6852 (in isoform 2) | Phosphorylation | - | 7.01 | 24719451 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SYNE2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SYNE2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SYNE2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SUN1_HUMAN | SUN1 | physical | 22632968 | |
| SUN2_HUMAN | SUN2 | physical | 22632968 | |
| MK01_HUMAN | MAPK1 | physical | 19861416 | |
| MK03_HUMAN | MAPK3 | physical | 19861416 | |
| PML_HUMAN | PML | physical | 19861416 | |
| BIN1_HUMAN | BIN1 | physical | 26506308 | |
| MKS3_HUMAN | TMEM67 | physical | 19596800 | |
| MKS1_HUMAN | MKS1 | physical | 19596800 |
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| Acetylation | |
| Reference | PubMed |
| "Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-955, AND MASS SPECTROMETRY. | |
| Phosphorylation | |
| Reference | PubMed |
| "Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-841; SER-4108; SER-4110AND TYR-4111, AND MASS SPECTROMETRY. | |
| "A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4108, AND MASSSPECTROMETRY. | |
| "Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2655 AND SER-6361, ANDMASS SPECTROMETRY. | |
