dbPTM

UN45A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	UN45A_HUMAN
UniProt AC	Q9H3U1
Protein Name	Protein unc-45 homolog A
Gene Name	UNC45A
Organism	Homo sapiens (Human).
Sequence Length	944
Subcellular Localization	Cytoplasm . Cytoplasm, perinuclear region . Nucleus . Predominant in the perinuclear region. Little protein in the nucleus.
Protein Description	Acts as co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen (By similarity)..
Protein Sequence	MTVSGPGTPEPRPATPGASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDMGETDLMLAALRTLVGICSEHQSRTVATLSILGTRRVVSILGVESQAVSLAACHLLQVMFDALKEGVKKGFRGKEGAIIVDPARELKVLISNLLDLLTEVGVSGQGRDNALTLLIKAVPRKSLKDPNNSLTLWVIDQGLKKILEVGGSLQDPPGELAVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKCSEKDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWLCNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDAAALKALFQLSRLEERSVLFAVASALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMVCMVKTESPVLTSSCRELLSRVFLALVEEVEDRGTVVAQGGGRALIPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLNCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFEAQGNDRLKLLVLYSGEDDELLQRAAAGGLAMLTSMRPTLCSRIPQVTTHWLEILQALLLSSNQELQHRGAVVVLNMVEASREIASTLMESEMMEILSVLAKGDHSPVTRAAAACLDKAVEYGLIQPNQDGE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTVSGPGTP ------CCCCCCCCC	24.31	27273156
2 (in isoform 2)	Phosphorylation	-	24.31	21406692
4	Phosphorylation	----MTVSGPGTPEP ----CCCCCCCCCCC	30.06	27273156
4 (in isoform 2)	Phosphorylation	-	30.06	21406692
5 (in isoform 2)	Phosphorylation	-	21.96	25159151
8	Phosphorylation	MTVSGPGTPEPRPAT CCCCCCCCCCCCCCC	27.84	23401153
15	O-linked_Glycosylation	TPEPRPATPGASSVE CCCCCCCCCCCCCHH	25.57	30379171
15	Phosphorylation	TPEPRPATPGASSVE CCCCCCCCCCCCCHH	25.57	19664994
18	Ubiquitination	PRPATPGASSVEQLR CCCCCCCCCCHHHHH	10.39	29967540
19	Phosphorylation	RPATPGASSVEQLRK CCCCCCCCCHHHHHH	40.61	30266825
20	Phosphorylation	PATPGASSVEQLRKE CCCCCCCCHHHHHHH	29.19	27273156
21	Ubiquitination	ATPGASSVEQLRKEG CCCCCCCHHHHHHHC	5.14	29967540
26	Ubiquitination	SSVEQLRKEGNELFK CCHHHHHHHCCCCEE	77.79	-
28	Ubiquitination	VEQLRKEGNELFKCG HHHHHHHCCCCEECC	35.63	27667366
33	Acetylation	KEGNELFKCGDYGGA HHCCCCEECCCHHHH	50.35	26051181
33	Ubiquitination	KEGNELFKCGDYGGA HHCCCCEECCCHHHH	50.35	29967540
45	Ubiquitination	GGALAAYTQALGLDA HHHHHHHHHHHCCCC	11.57	21890473
53	Phosphorylation	QALGLDATPQDQAVL HHHCCCCCHHHHHHH	22.58	25159151
55	Acetylation	LGLDATPQDQAVLHR HCCCCCHHHHHHHHH	51.60	19608861
55	Ubiquitination	LGLDATPQDQAVLHR HCCCCCHHHHHHHHH	51.60	29967540
55 (in isoform 2)	Malonylation	-	51.60	26320211
70	Acetylation	NRAACHLKLEDYDKA CCEEHHCCCCHHHHH	26.60	19608861
70	Malonylation	NRAACHLKLEDYDKA CCEEHHCCCCHHHHH	26.60	26320211
70	Ubiquitination	NRAACHLKLEDYDKA CCEEHHCCCCHHHHH	26.60	19608861
74	Phosphorylation	CHLKLEDYDKAETEA HHCCCCHHHHHHHHH	15.23	27642862
76	Acetylation	LKLEDYDKAETEASK CCCCHHHHHHHHHHH	41.72	26051181
78	Ubiquitination	LEDYDKAETEASKAI CCHHHHHHHHHHHHH	53.58	32015554
78 (in isoform 2)	Malonylation	-	53.58	26320211
83	Acetylation	KAETEASKAIEKDGG HHHHHHHHHHHHCCC	61.50	27452117
87	Acetylation	EASKAIEKDGGDVKA HHHHHHHHCCCCHHH	56.40	23749302
89	Ubiquitination	SKAIEKDGGDVKALY HHHHHHCCCCHHHHH	45.31	29967540
93	Malonylation	EKDGGDVKALYRRSQ HHCCCCHHHHHHHHH	37.10	26320211
93	Ubiquitination	EKDGGDVKALYRRSQ HHCCCCHHHHHHHHH	37.10	32015554
104	Ubiquitination	RRSQALEKLGRLDQA HHHHHHHHHCCHHHH	58.03	29967540
109	Ubiquitination	LEKLGRLDQAVLDLQ HHHHCCHHHHHHHHH	32.79	23000965
111	Ubiquitination	KLGRLDQAVLDLQRC HHCCHHHHHHHHHHH	11.96	23000965
111 (in isoform 2)	Malonylation	-	11.96	26320211
120	Phosphorylation	LDLQRCVSLEPKNKV HHHHHHHCCCCCCHH	30.55	28060719
124	Ubiquitination	RCVSLEPKNKVFQEA HHHCCCCCCHHHHHH	61.09	23000965
126	Malonylation	VSLEPKNKVFQEALR HCCCCCCHHHHHHHH	51.02	26320211
126	Ubiquitination	VSLEPKNKVFQEALR HCCCCCCHHHHHHHH	51.02	23000965
127	Ubiquitination	SLEPKNKVFQEALRN CCCCCCHHHHHHHHH	9.29	32015554
133	Methylation	KVFQEALRNIGGQIQ HHHHHHHHHCCHHHH	39.50	115919537
134	Ubiquitination	VFQEALRNIGGQIQE HHHHHHHHCCHHHHH	37.80	32015554
142	2-Hydroxyisobutyrylation	IGGQIQEKVRYMSST CCHHHHHHHHHHCCC	18.68	-
142	Ubiquitination	IGGQIQEKVRYMSST CCHHHHHHHHHHCCC	18.68	32015554
145	Phosphorylation	QIQEKVRYMSSTDAK HHHHHHHHHCCCCHH	12.34	27259358
147	Phosphorylation	QEKVRYMSSTDAKVE HHHHHHHCCCCHHHH	22.58	27259358
148	Phosphorylation	EKVRYMSSTDAKVEQ HHHHHHCCCCHHHHH	17.49	27259358
149	Phosphorylation	KVRYMSSTDAKVEQM HHHHHCCCCHHHHHH	32.44	27259358
151	Ubiquitination	RYMSSTDAKVEQMFQ HHHCCCCHHHHHHHH	20.20	29967540
158	Ubiquitination	AKVEQMFQILLDPEE HHHHHHHHHHHCHHH	21.78	27667366
166	Ubiquitination	ILLDPEEKGTEKKQK HHHCHHHCCCHHHHH	70.26	29967540
170	Ubiquitination	PEEKGTEKKQKASQN HHHCCCHHHHHHHCC	61.41	-
171	Ubiquitination	EEKGTEKKQKASQNL HHCCCHHHHHHHCCE	51.29	-
173	Acetylation	KGTEKKQKASQNLVV CCCHHHHHHHCCEEE	59.91	7408287
173	Ubiquitination	KGTEKKQKASQNLVV CCCHHHHHHHCCEEE	59.91	27667366
175	Ubiquitination	TEKKQKASQNLVVLA CHHHHHHHCCEEEEE	27.00	21890473
175	Ubiquitination	TEKKQKASQNLVVLA CHHHHHHHCCEEEEE	27.00	21890473
175 (in isoform 2)	Ubiquitination	-	27.00	21890473
176	Ubiquitination	EKKQKASQNLVVLAR HHHHHHHCCEEEEEE	52.73	33845483
181	Ubiquitination	ASQNLVVLAREDAGA HHCCEEEEEECCCCH	2.64	23503661
184	Ubiquitination	NLVVLAREDAGAEKI CEEEEEECCCCHHHH	46.75	21890473
190	Ubiquitination	REDAGAEKIFRSNGV ECCCCHHHHHHCCHH	46.76	27667366
190 (in isoform 1)	Ubiquitination	-	46.76	21890473
194	Phosphorylation	GAEKIFRSNGVQLLQ CHHHHHHCCHHHHHH	27.47	20068231
218	Phosphorylation	LMLAALRTLVGICSE HHHHHHHHHHHHHCH	27.01	-
224	Phosphorylation	RTLVGICSEHQSRTV HHHHHHHCHHCCCCE	35.87	-
232	Ubiquitination	EHQSRTVATLSILGT HHCCCCEEEHHHCCC	11.38	33845483
233	Phosphorylation	HQSRTVATLSILGTR HCCCCEEEHHHCCCC	19.39	22985185
235	Phosphorylation	SRTVATLSILGTRRV CCCEEEHHHCCCCHH	16.06	22985185
238	Ubiquitination	VATLSILGTRRVVSI EEEHHHCCCCHHHEC	18.59	29967540
239	Phosphorylation	ATLSILGTRRVVSIL EEHHHCCCCHHHECC	16.32	22985185
264	Ubiquitination	ACHLLQVMFDALKEG HHHHHHHHHHHHHHH	1.30	32015554
264 (in isoform 2)	Malonylation	-	1.30	26320211
266	Ubiquitination	HLLQVMFDALKEGVK HHHHHHHHHHHHHHH	32.66	21890473
269	Ubiquitination	QVMFDALKEGVKKGF HHHHHHHHHHHHHCC	54.89	21890473
274	Ubiquitination	ALKEGVKKGFRGKEG HHHHHHHHCCCCCCC	61.96	-
279	Malonylation	VKKGFRGKEGAIIVD HHHCCCCCCCEEEEC	49.03	26320211
279	Ubiquitination	VKKGFRGKEGAIIVD HHHCCCCCCCEEEEC	49.03	33845483
306	Ubiquitination	LDLLTEVGVSGQGRD HHHHHHHCCCCCCHH	11.14	33845483
306 (in isoform 2)	Ubiquitination	-	11.14	21890473
311	Ubiquitination	EVGVSGQGRDNALTL HHCCCCCCHHHHHHH	42.29	23503661
314	Ubiquitination	VSGQGRDNALTLLIK CCCCCHHHHHHHHHH	35.17	21890473
314	Ubiquitination	VSGQGRDNALTLLIK CCCCCHHHHHHHHHH	35.17	21890473
314 (in isoform 2)	Ubiquitination	-	35.17	21890473
317	Phosphorylation	QGRDNALTLLIKAVP CCHHHHHHHHHHHCC	19.67	20873877
321	Acetylation	NALTLLIKAVPRKSL HHHHHHHHHCCHHHC	43.21	23236377
321	Ubiquitination	NALTLLIKAVPRKSL HHHHHHHHHCCHHHC	43.21	21906983
321 (in isoform 1)	Ubiquitination	-	43.21	21890473
326	Ubiquitination	LIKAVPRKSLKDPNN HHHHCCHHHCCCCCC	54.81	23503661
327	Phosphorylation	IKAVPRKSLKDPNNS HHHCCHHHCCCCCCC	41.76	20873877
329	Ubiquitination	AVPRKSLKDPNNSLT HCCHHHCCCCCCCEE	77.54	21890473
329 (in isoform 1)	Ubiquitination	-	77.54	21890473
334	Phosphorylation	SLKDPNNSLTLWVID HCCCCCCCEEEEEEC	29.39	20873877
336	Phosphorylation	KDPNNSLTLWVIDQG CCCCCCEEEEEECHH	20.56	20873877
338	Ubiquitination	PNNSLTLWVIDQGLK CCCCEEEEEECHHHH	4.64	21890473
345	Acetylation	WVIDQGLKKILEVGG EEECHHHHHHHHCCC	44.59	24471315
362	Ubiquitination	QDPPGELAVTANSRM CCCCCCEEEECCCHH	7.72	33845483
368	Ubiquitination	LAVTANSRMSASILL EEEECCCHHHHHHHH	23.92	29967540
370	Phosphorylation	VTANSRMSASILLSK EECCCHHHHHHHHHH	20.11	21406692
371	Ubiquitination	TANSRMSASILLSKL ECCCHHHHHHHHHHH	7.40	32015554
372	Phosphorylation	ANSRMSASILLSKLF CCCHHHHHHHHHHHH	13.38	21406692
376	Phosphorylation	MSASILLSKLFDDLK HHHHHHHHHHHHHHC	24.70	21406692
377	Ubiquitination	SASILLSKLFDDLKC HHHHHHHHHHHHHCC	53.82	33845483
380	Ubiquitination	ILLSKLFDDLKCDAE HHHHHHHHHHCCHHH	71.42	32015554
383	Acetylation	SKLFDDLKCDAEREN HHHHHHHCCHHHHHH	36.74	25953088
383	Ubiquitination	SKLFDDLKCDAEREN HHHHHHHCCHHHHHH	36.74	29967540
396	Ubiquitination	ENFHRLCENYIKSWF HHHHHHHHHHHHHHH	58.63	21890473
396	Ubiquitination	ENFHRLCENYIKSWF HHHHHHHHHHHHHHH	58.63	21890473
396 (in isoform 2)	Ubiquitination	-	58.63	21890473
401	Phosphorylation	LCENYIKSWFEGQGL HHHHHHHHHHCCCCH	27.69	-
411	2-Hydroxyisobutyrylation	EGQGLAGKLRAIQTV CCCCHHHHHHHHHHH	29.23	-
411	Ubiquitination	EGQGLAGKLRAIQTV CCCCHHHHHHHHHHH	29.23	21890473
411 (in isoform 1)	Ubiquitination	-	29.23	21890473
468	Ubiquitination	LIHAAGKAKRASFIT HHHHHHHHHHHHEEE	12.97	21890473
468	Acetylation	LIHAAGKAKRASFIT HHHHHHHHHHHHEEE	12.97	19608861
468	Ubiquitination	LIHAAGKAKRASFIT HHHHHHHHHHHHEEE	12.97	21890473
468 (in isoform 2)	Ubiquitination	-	12.97	21890473
469	Ubiquitination	IHAAGKAKRASFITA HHHHHHHHHHHEEEE	52.57	29967540
472	Phosphorylation	AGKAKRASFITANGV HHHHHHHHEEEECHH	22.63	23403867
472	Ubiquitination	AGKAKRASFITANGV HHHHHHHHEEEECHH	22.63	29967540
475	Phosphorylation	AKRASFITANGVSLL HHHHHEEEECHHHHH	16.44	23403867
480	Phosphorylation	FITANGVSLLKDLYK EEEECHHHHHHHHHH	29.40	23403867
481	Ubiquitination	ITANGVSLLKDLYKC EEECHHHHHHHHHHC	6.82	29967540
483	Acetylation	ANGVSLLKDLYKCSE ECHHHHHHHHHHCCH	51.48	19608861
483	Ubiquitination	ANGVSLLKDLYKCSE ECHHHHHHHHHHCCH	51.48	21890473
483 (in isoform 1)	Ubiquitination	-	51.48	21890473
486	Phosphorylation	VSLLKDLYKCSEKDS HHHHHHHHHCCHHHH	21.78	20860994
487	Acetylation	SLLKDLYKCSEKDSI HHHHHHHHCCHHHHH	38.28	25953088
487	Ubiquitination	SLLKDLYKCSEKDSI HHHHHHHHCCHHHHH	38.28	-
492	Ubiquitination	LYKCSEKDSIRIRAL HHHCCHHHHHHHHHH	45.29	24816145
493	Phosphorylation	YKCSEKDSIRIRALV HHCCHHHHHHHHHHH	25.49	29142712
501	Ubiquitination	IRIRALVGLCKLGSA HHHHHHHHHHHHCCC	26.63	32015554
507	Phosphorylation	VGLCKLGSAGGTDFS HHHHHHCCCCCCCCC	33.89	25159151
510	Ubiquitination	CKLGSAGGTDFSMKQ HHHCCCCCCCCCHHH	23.10	32015554
514	Phosphorylation	SAGGTDFSMKQFAEG CCCCCCCCHHHHHCC	28.07	24719451
515	Sulfoxidation	AGGTDFSMKQFAEGS CCCCCCCHHHHHCCH	3.90	21406390
516	Ubiquitination	GGTDFSMKQFAEGST CCCCCCHHHHHCCHH	40.86	32015554
517 (in isoform 2)	Malonylation	-	33.85	26320211
523	Phosphorylation	KQFAEGSTLKLAKQC HHHHCCHHHHHHHHH	38.48	29496963
525	Acetylation	FAEGSTLKLAKQCRK HHCCHHHHHHHHHHH	46.62	25953088
525	Ubiquitination	FAEGSTLKLAKQCRK HHCCHHHHHHHHHHH	46.62	32015554
532	Malonylation	KLAKQCRKWLCNDQI HHHHHHHHHHHCCCC	52.74	26320211
553	Phosphorylation	WAVEGLAYLTFDADV HHEEEEEEEEECCCC	16.00	21949786
555	Phosphorylation	VEGLAYLTFDADVKE EEEEEEEEECCCCCH	13.54	21949786
562	Ubiquitination	TFDADVKEEFVEDAA EECCCCCHHHHHHHH	57.42	33845483
599	Ubiquitination	ALVNCTNSYDYEEPD HHHCCCCCCCCCCCC	10.96	29967540
602	Ubiquitination	NCTNSYDYEEPDPKM CCCCCCCCCCCCHHH	17.60	29967540
611	Ubiquitination	EPDPKMVELAKYAKQ CCCHHHHHHHHHHHH	39.24	29967540
613	Ubiquitination	DPKMVELAKYAKQHV CHHHHHHHHHHHHHC	6.84	29967540
614	Ubiquitination	PKMVELAKYAKQHVP HHHHHHHHHHHHHCC	59.36	29967540
617	Ubiquitination	VELAKYAKQHVPEQH HHHHHHHHHHCCCCC	37.54	29967540
626	Ubiquitination	HVPEQHPKDKPSFVR HCCCCCCCCCCHHHH	76.02	29967540
628	Ubiquitination	PEQHPKDKPSFVRAR CCCCCCCCCHHHHHH	49.00	29967540
668	Phosphorylation	SSCRELLSRVFLALV HHHHHHHHHHHHHHH	38.74	24719451
692	Ubiquitination	VAQGGGRALIPLALE EEECCCCEEEEEEEC	17.08	21890473
692	Ubiquitination	VAQGGGRALIPLALE EEECCCCEEEEEEEC	17.08	33845483
692 (in isoform 2)	Ubiquitination	-	17.08	21890473
701	Phosphorylation	IPLALEGTDVGQTKA EEEEECCCCCCHHHH	20.38	20068231
706	Phosphorylation	EGTDVGQTKAAQALA CCCCCCHHHHHHHHH	19.40	20068231
707	Ubiquitination	GTDVGQTKAAQALAK CCCCCHHHHHHHHHH	33.56	33845483
707 (in isoform 1)	Ubiquitination	-	33.56	21890473
714	Ubiquitination	KAAQALAKLTITSNP HHHHHHHHCCCCCCC	47.19	-
718	Phosphorylation	ALAKLTITSNPEMTF HHHHCCCCCCCCCCC	19.74	-
723	Sulfoxidation	TITSNPEMTFPGERI CCCCCCCCCCCCHHH	5.02	21406390
724	Phosphorylation	ITSNPEMTFPGERIY CCCCCCCCCCCHHHH	25.64	22210691
731	Phosphorylation	TFPGERIYEVVRPLV CCCCHHHHHHHHHHH	14.64	27273156
783	Phosphorylation	AVPMIEGYMFEEHEM CCCCCCCCCHHHHHH	5.95	-
785	Ubiquitination	PMIEGYMFEEHEMIR CCCCCCCHHHHHHHH	8.20	24816145
806	Ubiquitination	MCNLAMSKEVQDLFE HHHHHHCHHHHHHHH	49.14	-
826	Phosphorylation	RLKLLVLYSGEDDEL CEEEEEEECCCCHHH	13.72	25348772
827	Phosphorylation	LKLLVLYSGEDDELL EEEEEEECCCCHHHH	31.39	25348772
846	Phosphorylation	AGGLAMLTSMRPTLC HCHHHHHHHCCCCHH	13.85	28270605
847	Phosphorylation	GGLAMLTSMRPTLCS CHHHHHHHCCCCHHH	14.61	28270605
851	Phosphorylation	MLTSMRPTLCSRIPQ HHHHCCCCHHHCCCH	29.99	28270605
854	Phosphorylation	SMRPTLCSRIPQVTT HCCCCHHHCCCHHHH	36.04	28270605
893	Phosphorylation	VLNMVEASREIASTL EECHHHHHHHHHHHH	19.55	20068231
898	Phosphorylation	EASREIASTLMESEM HHHHHHHHHHHHHHH	27.95	26356563
899	Phosphorylation	ASREIASTLMESEMM HHHHHHHHHHHHHHH	22.54	26356563
903	Phosphorylation	IASTLMESEMMEILS HHHHHHHHHHHHHHH	19.48	26356563
915	Ubiquitination	ILSVLAKGDHSPVTR HHHHHHCCCCCHHHH	32.05	24816145
918	Phosphorylation	VLAKGDHSPVTRAAA HHHCCCCCHHHHHHH	26.30	26091039
930	Acetylation	AAAACLDKAVEYGLI HHHHHHHHHHHHCCC	41.19	26051181
930	Ubiquitination	AAAACLDKAVEYGLI HHHHHHHHHHHHCCC	41.19	24816145
934	Phosphorylation	CLDKAVEYGLIQPNQ HHHHHHHHCCCCCCC	15.61	28152594

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of UN45A_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of UN45A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of UN45A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
XPO2_HUMAN	CSE1L	physical	22939629
WDR5_HUMAN	WDR5	physical	22939629
UGGG1_HUMAN	UGGT1	physical	22863883
FA83H_HUMAN	FAM83H	physical	25036637
MARHA_HUMAN	MARCH10	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956
VATA_HUMAN	ATP6V1A	physical	26344197
SNAA_HUMAN	NAPA	physical	26344197
PPME1_HUMAN	PPME1	physical	26344197
GDS1_HUMAN	RAP1GDS1	physical	26344197
BRE1A_HUMAN	RNF20	physical	26344197
HS90A_HUMAN	HSP90AA1	physical	18285346
HS90B_HUMAN	HSP90AB1	physical	18285346
MYO5_YEAST	MYO5	physical	27888470
FA83H_HUMAN	FAM83H	physical	28514442
CDK17_HUMAN	CDK17	physical	28514442
MYH14_HUMAN	MYH14	physical	28514442
S27A2_HUMAN	SLC27A2	physical	28514442
MYO1E_HUMAN	MYO1E	physical	28514442
MYO1C_HUMAN	MYO1C	physical	28514442

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of UN45A_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-70 AND LYS-483, AND MASSSPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4; THR-8 AND THR-15, ANDMASS SPECTROMETRY.	19413330 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-15, AND MASSSPECTROMETRY.	18691976 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-15, AND MASSSPECTROMETRY.	17081983 [Abstract]