dbPTM

KI20A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KI20A_HUMAN
UniProt AC	O95235
Protein Name	Kinesin-like protein KIF20A
Gene Name	KIF20A
Organism	Homo sapiens (Human).
Sequence Length	890
Subcellular Localization	Golgi apparatus. Cytoplasm, cytoskeleton, spindle .
Protein Description	Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility..
Protein Sequence	MSQGILSPPAGLLSDDDVVVSPMFESTAADLGSVVRKNLLSDCSVVSTSLEDKQQVPSEDSMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTSLKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLPVPANIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALTTCDDILIKQDQTLAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQENQQPNQQPPGKKPFLRNLLPRTPTCQSSTDCSPYARILRSRRSPLLKSGPFGKKY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSQGILSPP ------CCCCCCCCC	36.79	20068231
2	Phosphorylation	------MSQGILSPP ------CCCCCCCCC	36.79	23663014
7	Phosphorylation	-MSQGILSPPAGLLS -CCCCCCCCCCCCCC	27.24	22199227
14	Phosphorylation	SPPAGLLSDDDVVVS CCCCCCCCCCCEEEC	44.00	20068231
21	Phosphorylation	SDDDVVVSPMFESTA CCCCEEECCCCCCCH	10.07	22199227
26	Phosphorylation	VVSPMFESTAADLGS EECCCCCCCHHHHHH	16.45	22199227
27	Phosphorylation	VSPMFESTAADLGSV ECCCCCCCHHHHHHH	20.76	22199227
33	Phosphorylation	STAADLGSVVRKNLL CCHHHHHHHHHHHHH	25.41	20068231
37	Ubiquitination	DLGSVVRKNLLSDCS HHHHHHHHHHHCCCE	40.10	29967540
41	Phosphorylation	VVRKNLLSDCSVVST HHHHHHHCCCEEEEC	39.47	24732914
44	Phosphorylation	KNLLSDCSVVSTSLE HHHHCCCEEEECCCC	30.46	24732914
47	Phosphorylation	LSDCSVVSTSLEDKQ HCCCEEEECCCCCCC	15.32	23663014
48	Phosphorylation	SDCSVVSTSLEDKQQ CCCEEEECCCCCCCC	26.22	23663014
49	Phosphorylation	DCSVVSTSLEDKQQV CCEEEECCCCCCCCC	23.43	25159151
58	Phosphorylation	EDKQQVPSEDSMEKV CCCCCCCCHHHHHHH	56.00	19691289
61	Phosphorylation	QQVPSEDSMEKVKVY CCCCCHHHHHHHHHH	25.45	19691289
84	Ubiquitination	SELERQEDQGCVRIE HHHHHCCCCCCEEEE	41.66	-
90	Ubiquitination	EDQGCVRIENVETLV CCCCCEEEECCEEEE	1.94	-
102	Ubiquitination	TLVLQAPKDSFALKS EEEEECCCCCEEECC	69.85	23503661
104	Phosphorylation	VLQAPKDSFALKSNE EEECCCCCEEECCCC	20.67	28555341
108	Ubiquitination	PKDSFALKSNERGIG CCCCEEECCCCCCCC	48.05	21906983
109	Phosphorylation	KDSFALKSNERGIGQ CCCEEECCCCCCCCH	44.78	20860994
132	Ubiquitination	QIFGPEVGQASFFNL HHHCCCCCCHHHEEC	18.70	-
146	Ubiquitination	LTVKEMVKDVLKGQN CCHHHHHHHHHCCCC	40.59	22817900
150	Ubiquitination	EMVKDVLKGQNWLIY HHHHHHHCCCCEEEE	59.30	21890473
150	Ubiquitination	EMVKDVLKGQNWLIY HHHHHHHCCCCEEEE	59.30	21890473
157	Ubiquitination	KGQNWLIYTYGVTNS CCCCEEEEEEEECCC	7.55	-
175	Ubiquitination	HTIQGTIKDGGILPR EEEEEEEECCCCCCH	50.59	21890473
175	Ubiquitination	HTIQGTIKDGGILPR EEEEEEEECCCCCCH	50.59	23000965
197	Ubiquitination	SLQGQLHPTPDLKPL HHCCCCCCCCCCHHH	54.97	-
198	Phosphorylation	LQGQLHPTPDLKPLL HCCCCCCCCCCHHHH	20.77	-
215	Ubiquitination	EVIWLDSKQIRQEEM CEEEECHHHHCHHHH	49.78	21890473
215	Ubiquitination	EVIWLDSKQIRQEEM CEEEECHHHHCHHHH	49.78	22817900
224	Ubiquitination	IRQEEMKKLSLLNGG HCHHHHHHHHHHCCC	41.83	-
224	Ubiquitination	IRQEEMKKLSLLNGG HCHHHHHHHHHHCCC	41.83	29967540
226	Phosphorylation	QEEMKKLSLLNGGLQ HHHHHHHHHHCCCCC	39.42	24719451
238	Phosphorylation	GLQEEELSTSLKRSV CCCHHHHCHHHCHHE	21.16	22199227
239	Phosphorylation	LQEEELSTSLKRSVY CCHHHHCHHHCHHEE	51.18	22199227
240	Phosphorylation	QEEELSTSLKRSVYI CHHHHCHHHCHHEEE	28.63	22199227
242	Ubiquitination	EELSTSLKRSVYIES HHHCHHHCHHEEEEC	42.25	21906983
244	Phosphorylation	LSTSLKRSVYIESRI HCHHHCHHEEEECCC	20.06	19691289
246	Phosphorylation	TSLKRSVYIESRIGT HHHCHHEEEECCCCC	10.54	19691289
249	Phosphorylation	KRSVYIESRIGTSTS CHHEEEECCCCCCCC	21.46	19691289
253	Phosphorylation	YIESRIGTSTSFDSG EEECCCCCCCCCCCC	26.85	24732914
254	Phosphorylation	IESRIGTSTSFDSGI EECCCCCCCCCCCCC	19.48	24732914
255	Phosphorylation	ESRIGTSTSFDSGIA ECCCCCCCCCCCCCC	33.00	24732914
256	Phosphorylation	SRIGTSTSFDSGIAG CCCCCCCCCCCCCCC	27.16	21712546
259	Phosphorylation	GTSTSFDSGIAGLSS CCCCCCCCCCCCCCC	30.04	24732914
265	Phosphorylation	DSGIAGLSSISQCTS CCCCCCCCCHHHCCC	25.38	23663014
266	Phosphorylation	SGIAGLSSISQCTSS CCCCCCCCHHHCCCC	31.16	23663014
268	Phosphorylation	IAGLSSISQCTSSSQ CCCCCCHHHCCCCHH	22.58	23663014
271	Phosphorylation	LSSISQCTSSSQLDE CCCHHHCCCCHHCCC	24.81	23663014
272	Phosphorylation	SSISQCTSSSQLDET CCHHHCCCCHHCCCC	35.30	23663014
273	Phosphorylation	SISQCTSSSQLDETS CHHHCCCCHHCCCCC	12.16	23663014
274	Phosphorylation	ISQCTSSSQLDETSH HHHCCCCHHCCCCCC	34.23	23663014
279	Phosphorylation	SSSQLDETSHRWAQP CCHHCCCCCCCCCCC	29.51	23663014
280	Phosphorylation	SSQLDETSHRWAQPD CHHCCCCCCCCCCCC	14.70	23663014
324	Ubiquitination	LEPPSQQRKRQTLRL HCCCCHHHHHHHHHH	28.61	-
328	Phosphorylation	SQQRKRQTLRLCEDQ CHHHHHHHHHHHCCC	20.20	25056879
342	Acetylation	QNGNPYVKDLNWIHV CCCCCCCCCCCEEEE	51.13	26051181
342	Ubiquitination	QNGNPYVKDLNWIHV CCCCCCCCCCCEEEE	51.13	21963094
346	Ubiquitination	PYVKDLNWIHVQDAE CCCCCCCEEEEECHH	6.86	-
357	Ubiquitination	QDAEEAWKLLKVGRK ECHHHHHHHHHHCCC	51.49	29967540
364	Ubiquitination	KLLKVGRKNQSFAST HHHHHCCCCCCCHHH	54.10	-
367	Phosphorylation	KVGRKNQSFASTHLN HHCCCCCCCHHHCCC	31.97	20873877
377	Phosphorylation	STHLNQNSSRSHSIF HHCCCCCCCCCCEEE	19.84	20860994
378	Phosphorylation	THLNQNSSRSHSIFS HCCCCCCCCCCEEEE	45.40	20860994
380	Phosphorylation	LNQNSSRSHSIFSIR CCCCCCCCCEEEEEE	24.43	24114839
382	Phosphorylation	QNSSRSHSIFSIRIL CCCCCCCEEEEEEEE	26.95	28348404
385	Phosphorylation	SRSHSIFSIRILHLQ CCCCEEEEEEEEEEC	14.86	22210691
402	Phosphorylation	GDIVPKISELSLCDL CCCCCCCCHHCHHHH	38.31	22210691
405	Phosphorylation	VPKISELSLCDLAGS CCCCCHHCHHHHCCC	23.93	22817900
407	Ubiquitination	KISELSLCDLAGSER CCCHHCHHHHCCCHH	3.46	-
412	Phosphorylation	SLCDLAGSERCKDQK CHHHHCCCHHHCCCC	19.09	22210691
419	Ubiquitination	SERCKDQKSGERLKE CHHHCCCCCCHHHHH	71.24	23503661
425	Ubiquitination	QKSGERLKEAGNINT CCCCHHHHHHCCCCH	52.30	21890473
425	Ubiquitination	QKSGERLKEAGNINT CCCCHHHHHHCCCCH	52.30	21906983
432	Phosphorylation	KEAGNINTSLHTLGR HHHCCCCHHHHHHHH	28.94	29214152
433	Phosphorylation	EAGNINTSLHTLGRC HHCCCCHHHHHHHHH	17.42	24719451
435	Ubiquitination	GNINTSLHTLGRCIA CCCCHHHHHHHHHHH	20.86	-
453	Ubiquitination	QNQQNRSKQNLVPFR HHHHCCCCCCCCCCC	39.71	29967540
478	Phosphorylation	FFTGRGRSCMIVNVN CCCCCCCCEEEEEEE	15.74	20068231
489	Phosphorylation	VNVNPCASTYDETLH EEEECCCCCCCCHHH	33.93	20068231
490	Phosphorylation	NVNPCASTYDETLHV EEECCCCCCCCHHHH	19.23	20068231
491	Phosphorylation	VNPCASTYDETLHVA EECCCCCCCCHHHHH	14.86	20068231
494	Phosphorylation	CASTYDETLHVAKFS CCCCCCCHHHHHHHH	21.18	20068231
519	Ubiquitination	PMQLGFPSLHSFIKE CHHCCCCCHHHHHHH	36.13	-
519	Phosphorylation	PMQLGFPSLHSFIKE CHHCCCCCHHHHHHH	36.13	22199227
522	Phosphorylation	LGFPSLHSFIKEHSL CCCCCHHHHHHHCCC	33.68	22199227
528	Phosphorylation	HSFIKEHSLQVSPSL HHHHHHCCCEECCCH	22.91	23927012
532	Phosphorylation	KEHSLQVSPSLEKGA HHCCCEECCCHHHCC	8.87	29255136
534	Phosphorylation	HSLQVSPSLEKGAKA CCCEECCCHHHCCCC	41.47	30266825
537	Ubiquitination	QVSPSLEKGAKADTG EECCCHHHCCCCCCC	70.26	33845483
540	Ubiquitination	PSLEKGAKADTGLDD CCHHHCCCCCCCCCH	56.30	-
543	Phosphorylation	EKGAKADTGLDDDIE HHCCCCCCCCCHHHC	44.49	21712546
556	Phosphorylation	IENEADISMYGKEEL HCCCHHHHHHCHHHH	13.39	25159151
558	Phosphorylation	NEADISMYGKEELLQ CCHHHHHHCHHHHHH	20.46	19691289
572	Phosphorylation	QVVEAMKTLLLKERQ HHHHHHHHHHHHHHH	15.00	19664994
576	Ubiquitination	AMKTLLLKERQEKLQ HHHHHHHHHHHHHHH	51.31	27667366
581	Ubiquitination	LLKERQEKLQLEMHL HHHHHHHHHHHHHHH	32.94	29967540
608	Phosphorylation	QQREQWCSEHLDTQK HHHHHHHHHHHHHHH	25.70	28555341
612	Ubiquitination	QWCSEHLDTQKELLE HHHHHHHHHHHHHHH	49.34	-
625	Ubiquitination	LEEMYEEKLNILKES HHHHHHHHHHHHHHH	34.59	22817900
629	Ubiquitination	YEEKLNILKESLTSF HHHHHHHHHHHHHHH	4.98	-
630	Ubiquitination	EEKLNILKESLTSFY HHHHHHHHHHHHHHH	41.27	21906983
632	Phosphorylation	KLNILKESLTSFYQE HHHHHHHHHHHHHHH	35.05	20068231
634	Phosphorylation	NILKESLTSFYQEEI HHHHHHHHHHHHHHH	26.52	20068231
635	Phosphorylation	ILKESLTSFYQEEIQ HHHHHHHHHHHHHHH	27.53	20068231
637	Phosphorylation	KESLTSFYQEEIQER HHHHHHHHHHHHHHH	18.12	20068231
647	Ubiquitination	EIQERDEKIEELEAL HHHHHHHHHHHHHHH	60.76	21890473
662	Phosphorylation	LQEARQQSVAHQQSG HHHHHHHHHHHHHCH	16.97	21082442
668	Phosphorylation	QSVAHQQSGSELALR HHHHHHHCHHHHHHH	37.40	25159151
670	Phosphorylation	VAHQQSGSELALRRS HHHHHCHHHHHHHHH	34.38	25159151
677	Phosphorylation	SELALRRSQRLAASA HHHHHHHHHHHHHCC	17.14	-
683	Phosphorylation	RSQRLAASASTQQLQ HHHHHHHCCCHHHHH	19.69	30266825
685	Phosphorylation	QRLAASASTQQLQEV HHHHHCCCHHHHHHH	25.01	30266825
686	Phosphorylation	RLAASASTQQLQEVK HHHHCCCHHHHHHHH	21.76	30266825
693	Ubiquitination	TQQLQEVKAKLQQCK HHHHHHHHHHHHHHH	38.77	29967540
705	Phosphorylation	QCKAELNSTTEELHK HHHHHHCCCHHHHHH	49.70	21712546
706	Phosphorylation	CKAELNSTTEELHKY HHHHHCCCHHHHHHH	36.83	21712546
712	Ubiquitination	STTEELHKYQKMLEP CCHHHHHHHHHHHCC	63.10	29967540
722	Phosphorylation	KMLEPPPSAKPFTID HHHCCCCCCCCCEEE	55.49	28674419
727	Phosphorylation	PPSAKPFTIDVDKKL CCCCCCCEEECHHHH	25.46	29396449
739	Ubiquitination	KKLEEGQKNIRLLRT HHHHHHHHHHHHHHH	66.26	29967540
750	Ubiquitination	LLRTELQKLGESLQS HHHHHHHHHHHHHHH	71.70	29967540
754	Phosphorylation	ELQKLGESLQSAERA HHHHHHHHHHHHHHH	29.88	28555341
757	Phosphorylation	KLGESLQSAERACCH HHHHHHHHHHHHHHH	37.07	21815630
770	Acetylation	CHSTGAGKLRQALTT HHCCCCHHHHHHHHH	39.71	25953088
816	Phosphorylation	CIAEQYHTVLKLQGQ HHHHHHHHHHHHHCC	23.69	28555341
819	Ubiquitination	EQYHTVLKLQGQVSA HHHHHHHHHHCCCHH	34.13	33845483
825	Phosphorylation	LKLQGQVSAKKRLGT HHHHCCCHHHHCCCC	26.87	30266825
827	Acetylation	LQGQVSAKKRLGTNQ HHCCCHHHHCCCCCC	30.81	25953088
827	Ubiquitination	LQGQVSAKKRLGTNQ HHCCCHHHHCCCCCC	30.81	29967540
832	Phosphorylation	SAKKRLGTNQENQQP HHHHCCCCCCCCCCC	38.02	21712546
846	Acetylation	PNQQPPGKKPFLRNL CCCCCCCCCCCHHHC	64.15	26051181
846	Ubiquitination	PNQQPPGKKPFLRNL CCCCCCCCCCCHHHC	64.15	33845483
857	Phosphorylation	LRNLLPRTPTCQSST HHHCCCCCCCCCCCC	22.47	27273156
859	Phosphorylation	NLLPRTPTCQSSTDC HCCCCCCCCCCCCCC	23.67	26055452
862	Phosphorylation	PRTPTCQSSTDCSPY CCCCCCCCCCCCCHH	37.03	19691289
863	Phosphorylation	RTPTCQSSTDCSPYA CCCCCCCCCCCCHHH	11.46	21712546
864	Phosphorylation	TPTCQSSTDCSPYAR CCCCCCCCCCCHHHH	46.39	27273156
867	Phosphorylation	CQSSTDCSPYARILR CCCCCCCCHHHHHHH	24.61	16964243
869	Phosphorylation	SSTDCSPYARILRSR CCCCCCHHHHHHHHC	7.69	22617229
875	Phosphorylation	PYARILRSRRSPLLK HHHHHHHHCCCCCHH	28.71	30576142
878	Phosphorylation	RILRSRRSPLLKSGP HHHHHCCCCCHHCCC	20.84	26055452
883	Phosphorylation	RRSPLLKSGPFGKKY CCCCCHHCCCCCCCC	52.23	12939256

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
7	S	Phosphorylation	Kinase	CDK1	P06493	PSP
21	S	Phosphorylation	Kinase	CDK1	P06493	PSP
198	T	Phosphorylation	Kinase	CDK1	P06493	PSP
240	S	Phosphorylation	Kinase	NEK6	Q9HC98	PSP
244	S	Phosphorylation	Kinase	NEK6	Q9HC98	PSP
528	S	Phosphorylation	Kinase	PLK1	P53350	Uniprot
532	S	Phosphorylation	Kinase	CDK1	P06493	PSP
683	S	Phosphorylation	Kinase	NEK6	Q9HC98	PSP
754	S	Phosphorylation	Kinase	NEK6	Q9HC98	PSP
857	T	Phosphorylation	Kinase	CDK1	P06493	PSP
867	S	Phosphorylation	Kinase	CDK1	P06493	PSP
878	S	Phosphorylation	Kinase	AURKB	Q96GD4	GPS
878	S	Phosphorylation	Kinase	CDK1	P06493	PSP
883	S	Phosphorylation	Kinase	NEK6	Q9HC98	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
528	S	Phosphorylation		12939256
Phosphorylated by PLK1 at Ser-528 during mitosis, creating a docking site for PLK1 and recruiting PLK1 at central spindle.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KI20A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZRAB2_HUMAN	ZRANB2	physical	21988832
F214B_HUMAN	FAM214B	physical	25416956
F214B_HUMAN	FAM214B	physical	21516116
CENPB_HUMAN	CENPB	physical	26496610
I5P2_HUMAN	INPP5B	physical	26496610
MBD1_HUMAN	MBD1	physical	26496610
NUMA1_HUMAN	NUMA1	physical	26496610
TSYL1_HUMAN	TSPYL1	physical	26496610
TERA_HUMAN	VCP	physical	26496610
TNKS1_HUMAN	TNKS	physical	26496610
HERC2_HUMAN	HERC2	physical	26496610
MBD4_HUMAN	MBD4	physical	26496610
SSA27_HUMAN	SSSCA1	physical	26496610
PTN23_HUMAN	PTPN23	physical	26496610
SERA_HUMAN	PHGDH	physical	26496610
CAR10_HUMAN	CARD10	physical	26496610
PKN3_HUMAN	PKN3	physical	26496610
BOREA_HUMAN	CDCA8	physical	26496610
SP130_HUMAN	SAP130	physical	26496610
NEUL4_HUMAN	NEURL4	physical	26496610
H6ST2_HUMAN	HS6ST2	physical	26496610

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KI20A_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-867, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-256; SER-528; SER-532;THR-857; THR-859 AND SER-867, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-532 AND SER-662, ANDMASS SPECTROMETRY.	18691976 [Abstract]
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis."; Wang B., Malik R., Nigg E.A., Korner R.; Anal. Chem. 80:9526-9533(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21; SER-238; SER-244;TYR-246; SER-249; SER-528; SER-532; SER-556; SER-670; SER-683; SER-825AND SER-867, AND MASS SPECTROMETRY.	19007248 [Abstract]
"Phosphoproteome analysis of the human mitotic spindle."; Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.; Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-49; SER-244; SER-528;SER-532; SER-556 AND SER-867, AND MASS SPECTROMETRY.	16565220 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-532, AND MASSSPECTROMETRY.	17081983 [Abstract]
"Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase1 is required for cytokinesis."; Neef R., Preisinger C., Sutcliffe J., Kopajtich R., Nigg E.A.,Mayer T.U., Barr F.A.; J. Cell Biol. 162:863-875(2003). Cited for: SUBCELLULAR LOCATION, INTERACTION WITH PLK1, PHOSPHORYLATION ATSER-528 AND SER-662, MUTAGENESIS OF SER-528, AND FUNCTION.	12939256 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-857 AND THR-859, ANDMASS SPECTROMETRY.	18220336 [Abstract]

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