CCD14_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCD14_HUMAN
• UniProt AC: Q49A88
• Protein Name: Coiled-coil domain-containing protein 14
• Gene Name: CCDC14
• Organism: Homo sapiens (Human).
• Sequence Length: 953
• Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Colocalizes with PCM1 at centriolar satellites throughout the cell cycle.
• Protein Description: Negatively regulates centriole duplication. Negatively regulates CEP63 and CDK2 centrosomal localization..
• Protein Sequence: MKRGIRRDPFRKRKLGGRAKKVREPTAVNSFYREASLPSVWASLRRREMVRSGARPGQVLSSGRHTGPAKLTNGKKATYLRKIPRFNADSGYSIHSDSESQAETVHGLDGCASLLRDILRNEDSGSETAYLENRSNSRPLESKRYGSKKKRHEKHTIPLVVQKETSSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQMSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNTSPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIREATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPLRSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKDQTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNLTKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQDSDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSRASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDANIARLQKSLRTGLLEK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
52	Phosphorylation	RRREMVRSGARPGQV HHHHHHHCCCCCCCC	25.95	-
73	Ubiquitination	TGPAKLTNGKKATYL CCCCCCCCCCCCEEE	71.38	23503661
73 (in isoform 2)	Ubiquitination	-	71.38	-
76	Phosphorylation	AKLTNGKKATYLRKI CCCCCCCCCEEEEEC	47.57	33259812
90	Phosphorylation	IPRFNADSGYSIHSD CCCCCCCCCCCCCCC	36.90	30576142
91	Ubiquitination	PRFNADSGYSIHSDS CCCCCCCCCCCCCCC	22.28	29967540
92	Phosphorylation	RFNADSGYSIHSDSE CCCCCCCCCCCCCCH	14.38	29978859
93	Phosphorylation	FNADSGYSIHSDSES CCCCCCCCCCCCCHH	19.83	29978859
96	Phosphorylation	DSGYSIHSDSESQAE CCCCCCCCCCHHHHH	40.96	30576142
98	Phosphorylation	GYSIHSDSESQAETV CCCCCCCCHHHHHHH	42.01	29978859
100	Phosphorylation	SIHSDSESQAETVHG CCCCCCHHHHHHHHC	38.35	29978859
104	Phosphorylation	DSESQAETVHGLDGC CCHHHHHHHHCHHHH	22.33	29978859
112	Ubiquitination	VHGLDGCASLLRDIL HHCHHHHHHHHHHHH	14.56	23503661
113	Ubiquitination	HGLDGCASLLRDILR HCHHHHHHHHHHHHH	31.82	23503661
117	Ubiquitination	GCASLLRDILRNEDS HHHHHHHHHHHCCCC	44.22	29967540
124	Phosphorylation	DILRNEDSGSETAYL HHHHCCCCCCCCEEC	37.73	22167270
126	Phosphorylation	LRNEDSGSETAYLEN HHCCCCCCCCEECCC	35.41	22167270
128	Phosphorylation	NEDSGSETAYLENRS CCCCCCCCEECCCCC	23.46	22167270
130	Phosphorylation	DSGSETAYLENRSNS CCCCCCEECCCCCCC	23.20	22167270
143	Ubiquitination	NSRPLESKRYGSKKK CCCCCCCCCCCCCCH	40.02	22817900
143 (in isoform 4)	Ubiquitination	-	40.02	21906983
146	Phosphorylation	PLESKRYGSKKKRHE CCCCCCCCCCCHHCC	36.70	-
153	Phosphorylation	GSKKKRHEKHTIPLV CCCCHHCCCCCCCEE	51.03	27251275
163	Ubiquitination	TIPLVVQKETSSSDN CCCEEEEECCCCCCC	51.88	29967540
165	Phosphorylation	PLVVQKETSSSDNKK CEEEEECCCCCCCCC	40.73	30206219
166	Phosphorylation	LVVQKETSSSDNKKQ EEEEECCCCCCCCCC	29.01	30206219
167	Phosphorylation	VVQKETSSSDNKKQI EEEECCCCCCCCCCC	49.48	30206219
168	Phosphorylation	VQKETSSSDNKKQIP EEECCCCCCCCCCCC	44.99	30206219
171	Ubiquitination	ETSSSDNKKQIPNEA CCCCCCCCCCCCCHH	51.55	-
172	Ubiquitination	TSSSDNKKQIPNEAS CCCCCCCCCCCCHHH	60.77	-
179	Phosphorylation	KQIPNEASARSERDT CCCCCHHHHCCCCCC	20.31	-
182	Ubiquitination	PNEASARSERDTSDL CCHHHHCCCCCCCHH	36.38	22817900
183	Ubiquitination	NEASARSERDTSDLE CHHHHCCCCCCCHHH	49.36	22817900
186	Phosphorylation	SARSERDTSDLEQNW HHCCCCCCCHHHHHC	30.29	27251275
187	Phosphorylation	ARSERDTSDLEQNWS HCCCCCCCHHHHHCC	44.48	26471730
189	Ubiquitination	SERDTSDLEQNWSLQ CCCCCCHHHHHCCHH	7.95	23000965
189 (in isoform 4)	Ubiquitination	-	7.95	21906983
192	Ubiquitination	DTSDLEQNWSLQDHY CCCHHHHHCCHHHHH	22.41	21963094
194	Phosphorylation	SDLEQNWSLQDHYRM CHHHHHCCHHHHHHH	24.57	27251275
198	Ubiquitination	QNWSLQDHYRMYSPI HHCCHHHHHHHHHHH	10.11	23503661
203	Ubiquitination	QDHYRMYSPIIYQAL HHHHHHHHHHHHHHH	10.57	29967540
204	Ubiquitination	DHYRMYSPIIYQALC HHHHHHHHHHHHHHH	10.25	27667366
215	Ubiquitination	QALCEHVQTQMSLMN HHHHHHHHHHHHHHH	28.11	22817900
216	Ubiquitination	ALCEHVQTQMSLMND HHHHHHHHHHHHHHH	25.75	27667366
217	Ubiquitination	LCEHVQTQMSLMNDL HHHHHHHHHHHHHHH	11.45	22817900
228	Ubiquitination	MNDLTSKNIPNGIPA HHHHHHCCCCCCCCC	55.50	23000965
229	Ubiquitination	NDLTSKNIPNGIPAV HHHHHCCCCCCCCCC	3.01	23000965
232	Ubiquitination	TSKNIPNGIPAVPCH HHCCCCCCCCCCCCC	23.15	23503661
242	Ubiquitination	AVPCHAPSHSESQAT CCCCCCCCCCCCCCC	40.19	22817900
242 (in isoform 4)	Ubiquitination	-	40.19	21906983
247	Ubiquitination	APSHSESQATPHSSY CCCCCCCCCCCCCCC	45.24	22817900
250	Ubiquitination	HSESQATPHSSYGLC CCCCCCCCCCCCCCC	28.51	-
252	Ubiquitination	ESQATPHSSYGLCTS CCCCCCCCCCCCCCC	26.85	22817900
255	Ubiquitination	ATPHSSYGLCTSTPV CCCCCCCCCCCCCCC	19.07	27667366
256	Ubiquitination	TPHSSYGLCTSTPVW CCCCCCCCCCCCCCC	1.87	27667366
258	Ubiquitination	HSSYGLCTSTPVWSL CCCCCCCCCCCCCCC	40.45	22817900
263	Phosphorylation	LCTSTPVWSLQRPPC CCCCCCCCCCCCCCC	8.43	24719451
267	Phosphorylation	TPVWSLQRPPCPPKV CCCCCCCCCCCCCCC	42.28	-
273	Ubiquitination	QRPPCPPKVHSEVQT CCCCCCCCCCCEEEC	37.41	23503661
276	Ubiquitination	PCPPKVHSEVQTDGN CCCCCCCCEEECCCC	42.31	-
281	Ubiquitination	VHSEVQTDGNSQFAS CCCEEECCCCCCHHH	36.87	22817900
282	Ubiquitination	HSEVQTDGNSQFASQ CCEEECCCCCCHHHC	38.79	22817900
288	Phosphorylation	DGNSQFASQGKTVSA CCCCCHHHCCCEEEE	40.53	28555341
290	Ubiquitination	NSQFASQGKTVSATC CCCHHHCCCEEEEHH	25.71	21963094
291	Ubiquitination	SQFASQGKTVSATCT CCHHHCCCEEEEHHH	37.81	-
295 (in isoform 1)	Ubiquitination	-	11.45	21906983
295 (in isoform 2)	Ubiquitination	-	11.45	21906983
296	Phosphorylation	QGKTVSATCTDVLRN CCCEEEEHHHHHHHH	14.39	27251275
298	Phosphorylation	KTVSATCTDVLRNSF CEEEEHHHHHHHHCC	25.45	27251275
302	Ubiquitination	ATCTDVLRNSFNTSP EHHHHHHHHCCCCCC	36.27	22817900
302 (in isoform 3)	Ubiquitination	-	36.27	21906983
304	Phosphorylation	CTDVLRNSFNTSPGV HHHHHHHCCCCCCCC	17.28	27251275
307	Phosphorylation	VLRNSFNTSPGVPCS HHHHCCCCCCCCCCC	34.00	25627689
308	Phosphorylation	LRNSFNTSPGVPCSL HHHCCCCCCCCCCCC	22.29	25159151
308	Ubiquitination	LRNSFNTSPGVPCSL HHHCCCCCCCCCCCC	22.29	-
317	Ubiquitination	GVPCSLPKTDISAIP CCCCCCCCCCCCCCC	65.21	-
322	Ubiquitination	LPKTDISAIPTLQQL CCCCCCCCCCHHHHH	16.47	-
333	Phosphorylation	LQQLGLVNGILPQQG HHHHCCCCCCCCCCC	36.51	24719451
341	Ubiquitination	GILPQQGIHKETDLL CCCCCCCCCCHHHHH	3.49	33845483
341 (in isoform 1)	Ubiquitination	-	3.49	21906983
341 (in isoform 2)	Ubiquitination	-	3.49	21906983
343	Ubiquitination	LPQQGIHKETDLLKC CCCCCCCCHHHHHHH	61.46	22817900
344 (in isoform 5)	Ubiquitination	-	33.13	21906983
348	Ubiquitination	IHKETDLLKCIQTYL CCCHHHHHHHHHHHH	4.78	23000965
348 (in isoform 3)	Ubiquitination	-	4.78	21906983
349	Ubiquitination	HKETDLLKCIQTYLS CCHHHHHHHHHHHHH	36.27	-
351	Ubiquitination	ETDLLKCIQTYLSLF HHHHHHHHHHHHHHH	3.07	27667366
351 (in isoform 2)	Ubiquitination	-	3.07	-
351 (in isoform 4)	Ubiquitination	-	3.07	21906983
356	Phosphorylation	KCIQTYLSLFRSHGK HHHHHHHHHHHHCCC	18.30	24719451
357	Ubiquitination	CIQTYLSLFRSHGKE HHHHHHHHHHHCCCC	3.69	23503661
362	Ubiquitination	LSLFRSHGKETHLDS HHHHHHCCCCCCCCC	30.64	-
363	Ubiquitination	SLFRSHGKETHLDSQ HHHHHCCCCCCCCCC	54.75	22817900
367 (in isoform 5)	Ubiquitination	-	9.89	21906983
369	Phosphorylation	GKETHLDSQTHRSPT CCCCCCCCCCCCCCC	43.25	25159151
371	Phosphorylation	ETHLDSQTHRSPTQS CCCCCCCCCCCCCCC	24.17	30576142
374	Phosphorylation	LDSQTHRSPTQSQPA CCCCCCCCCCCCCCC	25.37	30266825
374	Ubiquitination	LDSQTHRSPTQSQPA CCCCCCCCCCCCCCC	25.37	22817900
374 (in isoform 4)	Ubiquitination	-	25.37	21906983
375	Sumoylation	DSQTHRSPTQSQPAF CCCCCCCCCCCCCCE	34.12	-
375	Ubiquitination	DSQTHRSPTQSQPAF CCCCCCCCCCCCCCE	34.12	27667366
376	Phosphorylation	SQTHRSPTQSQPAFL CCCCCCCCCCCCCEE	41.94	30266825
376	Ubiquitination	SQTHRSPTQSQPAFL CCCCCCCCCCCCCEE	41.94	22817900
378	Phosphorylation	THRSPTQSQPAFLAT CCCCCCCCCCCEECC	40.38	23663014
389	Ubiquitination	FLATNEEKCAREQIR EECCCHHHHHHHHHH	27.32	23000965
390	Ubiquitination	LATNEEKCAREQIRE ECCCHHHHHHHHHHH	4.96	21963094
391	Ubiquitination	ATNEEKCAREQIREA CCCHHHHHHHHHHHH	29.16	21963094
392	Ubiquitination	TNEEKCAREQIREAT CCHHHHHHHHHHHHH	45.91	21963094
394	Ubiquitination	EEKCAREQIREATSE HHHHHHHHHHHHHHH	34.19	-
394 (in isoform 1)	Ubiquitination	-	34.19	21906983
394 (in isoform 2)	Ubiquitination	-	34.19	21906983
396	Ubiquitination	KCAREQIREATSERK HHHHHHHHHHHHHCC	27.47	23503661
397	Ubiquitination	CAREQIREATSERKD HHHHHHHHHHHHCCC	58.91	23503661
398	Ubiquitination	AREQIREATSERKDL HHHHHHHHHHHCCCC	13.43	23503661
399 (in isoform 5)	Ubiquitination	-	26.77	21906983
401	Ubiquitination	QIREATSERKDLNIH HHHHHHHHCCCCCEE	60.44	22817900
401 (in isoform 3)	Ubiquitination	-	60.44	21906983
402	Ubiquitination	IREATSERKDLNIHV HHHHHHHCCCCCEEC	37.24	27667366
403	Ubiquitination	REATSERKDLNIHVR HHHHHHCCCCCEECC	63.62	27667366
404	Ubiquitination	EATSERKDLNIHVRD HHHHHCCCCCEECCC	51.69	27667366
406	Ubiquitination	TSERKDLNIHVRDTK HHHCCCCCEECCCCC	32.24	32015554
406 (in isoform 2)	Ubiquitination	-	32.24	-
406 (in isoform 4)	Ubiquitination	-	32.24	21906983
410 (in isoform 5)	Ubiquitination	-	31.55	21906983
411	Ubiquitination	DLNIHVRDTKTVKDV CCCEECCCCCHHHHH	52.01	22817900
413	Ubiquitination	NIHVRDTKTVKDVQK CEECCCCCHHHHHHH	56.46	22817900
414	Ubiquitination	IHVRDTKTVKDVQKA EECCCCCHHHHHHHH	34.58	22817900
415	Ubiquitination	HVRDTKTVKDVQKAK ECCCCCHHHHHHHHH	5.48	22817900
416	Sumoylation	VRDTKTVKDVQKAKN CCCCCHHHHHHHHHC	58.37	-
416	Ubiquitination	VRDTKTVKDVQKAKN CCCCCHHHHHHHHHC	58.37	22817900
417	Ubiquitination	RDTKTVKDVQKAKNV CCCCHHHHHHHHHCC	43.68	22817900
417 (in isoform 4)	Ubiquitination	-	43.68	21906983
435	Ubiquitination	AEKVRIIKYLLGELK HHHHHHHHHHHHHHH	27.72	-
436	Phosphorylation	EKVRIIKYLLGELKA HHHHHHHHHHHHHHH	9.21	-
442	Ubiquitination	KYLLGELKALVAEQE HHHHHHHHHHHHCCC	35.06	22817900
445	Ubiquitination	LGELKALVAEQEDSE HHHHHHHHHCCCCHH	7.05	22817900
446	Ubiquitination	GELKALVAEQEDSEI HHHHHHHHCCCCHHH	17.38	22817900
447	Ubiquitination	ELKALVAEQEDSEIQ HHHHHHHCCCCHHHH	47.20	22817900
449	Ubiquitination	KALVAEQEDSEIQRL HHHHHCCCCHHHHHH	55.82	21963094
449 (in isoform 2)	Ubiquitination	-	55.82	-
450	Ubiquitination	ALVAEQEDSEIQRLI HHHHCCCCHHHHHHH	51.79	22817900
451	Ubiquitination	LVAEQEDSEIQRLIT HHHCCCCHHHHHHHH	35.53	22817900
452	Ubiquitination	VAEQEDSEIQRLITE HHCCCCHHHHHHHHH	56.30	22817900
456	Ubiquitination	EDSEIQRLITEMEAC CCHHHHHHHHHHHHH	3.05	22817900
457	Ubiquitination	DSEIQRLITEMEACI CHHHHHHHHHHHHHH	3.14	22817900
458	Ubiquitination	SEIQRLITEMEACIS HHHHHHHHHHHHHHH	33.59	22817900
462	Ubiquitination	RLITEMEACISVLPT HHHHHHHHHHHHCCC	8.47	22817900
465	Ubiquitination	TEMEACISVLPTVSG HHHHHHHHHCCCCCC	19.93	22817900
469	Ubiquitination	ACISVLPTVSGNTDI HHHHHCCCCCCCCCH	24.12	29967540
477	Ubiquitination	VSGNTDIQVEIALAM CCCCCCHHHHHHHHH	29.60	21963094
478	Ubiquitination	SGNTDIQVEIALAMQ CCCCCHHHHHHHHHC	6.16	22817900
481	Ubiquitination	TDIQVEIALAMQPLR CCHHHHHHHHHCCCC	3.93	22817900
485	Ubiquitination	VEIALAMQPLRSENA HHHHHHHCCCCCCCH	28.41	22817900
488	Ubiquitination	ALAMQPLRSENAQLR HHHHCCCCCCCHHHH	48.91	21963094
489	Ubiquitination	LAMQPLRSENAQLRR HHHCCCCCCCHHHHH	42.77	21963094
490	Ubiquitination	AMQPLRSENAQLRRQ HHCCCCCCCHHHHHH	50.59	21963094
493	Ubiquitination	PLRSENAQLRRQLRI CCCCCCHHHHHHHHH	47.27	21963094
499	Ubiquitination	AQLRRQLRILNQQLR HHHHHHHHHHHHHHH	24.02	27667366
501	Ubiquitination	LRRQLRILNQQLREQ HHHHHHHHHHHHHHH	3.70	22817900
502	Ubiquitination	RRQLRILNQQLREQQ HHHHHHHHHHHHHHH	25.77	27667366
503 (in isoform 1)	Ubiquitination	-	39.99	21906983
503 (in isoform 2)	Ubiquitination	-	39.99	21906983
507	Ubiquitination	ILNQQLREQQKTQKP HHHHHHHHHHCCCCC	66.99	27667366
509	Ubiquitination	NQQLREQQKTQKPSG HHHHHHHHCCCCCCC	46.11	22817900
510	Ubiquitination	QQLREQQKTQKPSGA HHHHHHHCCCCCCCC	53.25	21963094
510 (in isoform 3)	Ubiquitination	-	53.25	21906983
513	Ubiquitination	REQQKTQKPSGAVDC HHHHCCCCCCCCCCC	46.51	21963094
515	Ubiquitination	QQKTQKPSGAVDCNL HHCCCCCCCCCCCCE	46.55	27667366
515 (in isoform 5)	Ubiquitination	-	46.55	21906983
516	Ubiquitination	QKTQKPSGAVDCNLE HCCCCCCCCCCCCEE	37.84	23503661
518	Ubiquitination	TQKPSGAVDCNLELF CCCCCCCCCCCEEEE	11.13	27667366
519	Ubiquitination	QKPSGAVDCNLELFS CCCCCCCCCCEEEEE	18.30	22817900
522	Ubiquitination	SGAVDCNLELFSLQS CCCCCCCEEEEEHHH	8.33	22817900
523	Ubiquitination	GAVDCNLELFSLQSL CCCCCCEEEEEHHHH	33.50	27667366
526 (in isoform 1)	Ubiquitination	-	37.82	21906983
526 (in isoform 2)	Ubiquitination	-	37.82	21906983
528	Ubiquitination	NLELFSLQSLNMSLQ CEEEEEHHHHCHHHH	44.68	32142685
529	Ubiquitination	LELFSLQSLNMSLQN EEEEEHHHHCHHHHH	27.31	21963094
533	Ubiquitination	SLQSLNMSLQNQLEE EHHHHCHHHHHHHHH	26.23	22817900
533 (in isoform 3)	Ubiquitination	-	26.23	21906983
534	Ubiquitination	LQSLNMSLQNQLEES HHHHCHHHHHHHHHH	3.74	21963094
535	Ubiquitination	QSLNMSLQNQLEESL HHHCHHHHHHHHHHH	28.46	22817900
541	Phosphorylation	LQNQLEESLKSQELL HHHHHHHHHHHHHHH	31.55	-
542	Ubiquitination	QNQLEESLKSQELLQ HHHHHHHHHHHHHHH	7.57	22817900
543	Ubiquitination	NQLEESLKSQELLQS HHHHHHHHHHHHHHH	60.41	-
544	Phosphorylation	QLEESLKSQELLQSK HHHHHHHHHHHHHHC	33.89	-
550	Phosphorylation	KSQELLQSKNEELLK HHHHHHHHCCHHHHH	37.10	-
550	Ubiquitination	KSQELLQSKNEELLK HHHHHHHHCCHHHHH	37.10	22817900
551	Ubiquitination	SQELLQSKNEELLKV HHHHHHHCCHHHHHH	56.25	21906983
556	Ubiquitination	QSKNEELLKVIENQK HHCCHHHHHHHHCCC	4.75	27667366
557	Ubiquitination	SKNEELLKVIENQKD HCCHHHHHHHHCCCC	54.51	23503661
558	Ubiquitination	KNEELLKVIENQKDE CCHHHHHHHHCCCCC	7.19	32015554
558 (in isoform 1)	Ubiquitination	-	7.19	21906983
558 (in isoform 2)	Ubiquitination	-	7.19	21906983
559	Ubiquitination	NEELLKVIENQKDEN CHHHHHHHHCCCCCC	3.83	27667366
561	Ubiquitination	ELLKVIENQKDENKK HHHHHHHCCCCCCCC	42.98	22817900
562	Ubiquitination	LLKVIENQKDENKKF HHHHHHCCCCCCCCH	41.61	22817900
563	Ubiquitination	LKVIENQKDENKKFS HHHHHCCCCCCCCHH	77.81	22817900
564	Ubiquitination	KVIENQKDENKKFSS HHHHCCCCCCCCHHH	55.74	27667366
565	Ubiquitination	VIENQKDENKKFSSI HHHCCCCCCCCHHHH	77.36	22817900
565 (in isoform 3)	Ubiquitination	-	77.36	21906983
569 (in isoform 1)	Ubiquitination	-	8.06	21906983
569 (in isoform 2)	Ubiquitination	-	8.06	21906983
570	Ubiquitination	KDENKKFSSIFKDKD CCCCCCHHHHHCCCC	31.25	21963094
571	Phosphorylation	DENKKFSSIFKDKDQ CCCCCHHHHHCCCCC	34.87	24719451
574	Ubiquitination	KKFSSIFKDKDQTIL CCHHHHHCCCCCHHH	63.30	22817900
576	Ubiquitination	FSSIFKDKDQTILEN HHHHHCCCCCHHHHC	52.94	22817900
576 (in isoform 3)	Ubiquitination	-	52.94	21906983
584	Ubiquitination	DQTILENKQQYDIEI CCHHHHCHHCCCEEE	29.42	-
585	Ubiquitination	QTILENKQQYDIEIT CHHHHCHHCCCEEEE	59.66	27667366
601	Ubiquitination	IKIELEEALVNVKSS EEEEHHHHHHHHCHH	13.87	27667366
606	Ubiquitination	EEALVNVKSSQFKLE HHHHHHHCHHCCEEE	38.90	21906983
608	Ubiquitination	ALVNVKSSQFKLETA HHHHHCHHCCEEEEH	33.64	21963094
611	Ubiquitination	NVKSSQFKLETAEKE HHCHHCCEEEEHHHH	37.46	22817900
614	Phosphorylation	SSQFKLETAEKENQI HHCCEEEEHHHHHCE	51.02	24719451
614 (in isoform 5)	Ubiquitination	-	51.02	21906983
617	Phosphorylation	FKLETAEKENQILGI CEEEEHHHHHCEEEE	60.55	-
617	Ubiquitination	FKLETAEKENQILGI CEEEEHHHHHCEEEE	60.55	22817900
621	Ubiquitination	TAEKENQILGITLRQ EHHHHHCEEEEEEHH	6.00	22817900
624	Ubiquitination	KENQILGITLRQRDA HHHCEEEEEEHHHHH	2.69	22817900
628	Ubiquitination	ILGITLRQRDAEVTR EEEEEEHHHHHHHHH	51.20	-
629	Phosphorylation	LGITLRQRDAEVTRL EEEEEHHHHHHHHHH	38.38	24719451
636	Ubiquitination	RDAEVTRLRELTRTL HHHHHHHHHHHHHHH	3.49	21963094
637 (in isoform 5)	Ubiquitination	-	33.32	21906983
642	Ubiquitination	RLRELTRTLQTSMAK HHHHHHHHHHHHHHH	20.27	27667366
644	Ubiquitination	RELTRTLQTSMAKLL HHHHHHHHHHHHHHH	30.80	22817900
645 (in isoform 5)	Ubiquitination	-	24.47	21906983
649	Ubiquitination	TLQTSMAKLLSDLSV HHHHHHHHHHHCCCC	41.12	21963094
652	Ubiquitination	TSMAKLLSDLSVDSA HHHHHHHHCCCCCCC	47.11	22817900
655	Phosphorylation	AKLLSDLSVDSARCK HHHHHCCCCCCCCCC	28.95	24719451
658	Phosphorylation	LSDLSVDSARCKPGN HHCCCCCCCCCCCCC	18.56	23186163
658	Ubiquitination	LSDLSVDSARCKPGN HHCCCCCCCCCCCCC	18.56	27667366
659	Ubiquitination	SDLSVDSARCKPGNN HCCCCCCCCCCCCCC	19.20	29967540
660	Ubiquitination	DLSVDSARCKPGNNL CCCCCCCCCCCCCCH	32.70	22817900
661	Ubiquitination	LSVDSARCKPGNNLT CCCCCCCCCCCCCHH	6.62	22817900
662	Ubiquitination	SVDSARCKPGNNLTK CCCCCCCCCCCCHHH	50.86	22817900
663	Ubiquitination	VDSARCKPGNNLTKS CCCCCCCCCCCHHHH	55.13	22817900
664	Ubiquitination	DSARCKPGNNLTKSL CCCCCCCCCCHHHHH	22.58	22817900
665	Ubiquitination	SARCKPGNNLTKSLL CCCCCCCCCHHHHHH	49.19	22817900
666	Ubiquitination	ARCKPGNNLTKSLLN CCCCCCCCHHHHHHH	55.81	27667366
669	Phosphorylation	KPGNNLTKSLLNIHD CCCCCHHHHHHHHCH	42.12	-
669	Ubiquitination	KPGNNLTKSLLNIHD CCCCCHHHHHHHHCH	42.12	-
670	Phosphorylation	PGNNLTKSLLNIHDK CCCCHHHHHHHHCHH	32.62	30266825
672	Ubiquitination	NNLTKSLLNIHDKQL CCHHHHHHHHCHHHC	7.95	21963094
674 (in isoform 1)	Ubiquitination	-	4.48	21906983
674 (in isoform 2)	Ubiquitination	-	4.48	21906983
675	Ubiquitination	TKSLLNIHDKQLQHD HHHHHHHCHHHCCCC	34.83	21963094
676	Ubiquitination	KSLLNIHDKQLQHDP HHHHHHCHHHCCCCC	36.28	21963094
677	Ubiquitination	SLLNIHDKQLQHDPA HHHHHCHHHCCCCCC	38.45	21963094
678	Ubiquitination	LLNIHDKQLQHDPAP HHHHCHHHCCCCCCC	53.03	22817900
681	Ubiquitination	IHDKQLQHDPAPAHT HCHHHCCCCCCCCHH	52.17	22817900
681 (in isoform 3)	Ubiquitination	-	52.17	21906983
683	Phosphorylation	DKQLQHDPAPAHTSI HHHCCCCCCCCHHHH	37.71	-
683	Ubiquitination	DKQLQHDPAPAHTSI HHHCCCCCCCCHHHH	37.71	22817900
684	Ubiquitination	KQLQHDPAPAHTSIM HHCCCCCCCCHHHHH	21.70	22817900
685	Ubiquitination	QLQHDPAPAHTSIMS HCCCCCCCCHHHHHH	29.93	22817900
691	Ubiquitination	APAHTSIMSYLNKLE CCCHHHHHHHHHHHC	1.84	22817900
692	Ubiquitination	PAHTSIMSYLNKLET CCHHHHHHHHHHHCC	25.46	22817900
693	Ubiquitination	AHTSIMSYLNKLETN CHHHHHHHHHHHCCC	9.27	21963094
697	Ubiquitination	IMSYLNKLETNYSFT HHHHHHHHCCCCCCC	10.77	27667366
698	Ubiquitination	MSYLNKLETNYSFTH HHHHHHHCCCCCCCC	36.29	27667366
699	Ubiquitination	SYLNKLETNYSFTHS HHHHHHCCCCCCCCC	50.31	27667366
700	Ubiquitination	YLNKLETNYSFTHSE HHHHHCCCCCCCCCC	22.52	27667366
701	Phosphorylation	LNKLETNYSFTHSEP HHHHCCCCCCCCCCC	16.75	25159151
701	Ubiquitination	LNKLETNYSFTHSEP HHHHCCCCCCCCCCC	16.75	22817900
702	Phosphorylation	NKLETNYSFTHSEPL HHHCCCCCCCCCCCC	26.24	25159151
702	Ubiquitination	NKLETNYSFTHSEPL HHHCCCCCCCCCCCC	26.24	27667366
705	Ubiquitination	ETNYSFTHSEPLSTI CCCCCCCCCCCCCCC	28.31	27667366
706	Ubiquitination	TNYSFTHSEPLSTIK CCCCCCCCCCCCCCC	37.54	27667366
707	Ubiquitination	NYSFTHSEPLSTIKN CCCCCCCCCCCCCCC	42.53	27667366
709	Ubiquitination	SFTHSEPLSTIKNEE CCCCCCCCCCCCCCC	6.56	22817900
710	Phosphorylation	FTHSEPLSTIKNEET CCCCCCCCCCCCCCC	38.51	24275569
711	Phosphorylation	THSEPLSTIKNEETI CCCCCCCCCCCCCCC	43.59	24275569
711	Ubiquitination	THSEPLSTIKNEETI CCCCCCCCCCCCCCC	43.59	21963094
712	Ubiquitination	HSEPLSTIKNEETIE CCCCCCCCCCCCCCC	3.97	21963094
713	Phosphorylation	SEPLSTIKNEETIEP CCCCCCCCCCCCCCC	59.40	27251275
713	Ubiquitination	SEPLSTIKNEETIEP CCCCCCCCCCCCCCC	59.40	21963094
715	Ubiquitination	PLSTIKNEETIEPDK CCCCCCCCCCCCCCC	52.06	27667366
717	Phosphorylation	STIKNEETIEPDKTY CCCCCCCCCCCCCCH	25.18	-
718	Ubiquitination	TIKNEETIEPDKTYE CCCCCCCCCCCCCHH	9.05	27667366
721	Phosphorylation	NEETIEPDKTYENVL CCCCCCCCCCHHHHH	43.04	-
722	Ubiquitination	EETIEPDKTYENVLS CCCCCCCCCHHHHHH	64.82	22817900
723	Phosphorylation	ETIEPDKTYENVLSS CCCCCCCCHHHHHHC	43.37	29978859
723	Ubiquitination	ETIEPDKTYENVLSS CCCCCCCCHHHHHHC	43.37	27667366
724	Phosphorylation	TIEPDKTYENVLSSR CCCCCCCHHHHHHCC	15.96	28796482
729	Phosphorylation	KTYENVLSSRGPQNS CCHHHHHHCCCCCCC	17.44	29978859
729	Ubiquitination	KTYENVLSSRGPQNS CCHHHHHHCCCCCCC	17.44	21963094
730	Phosphorylation	TYENVLSSRGPQNSN CHHHHHHCCCCCCCC	36.78	24719451
744	Phosphorylation	NTRGMEEASAPGIIS CCCCCHHHCCCCHHH	9.55	24719451
744	Ubiquitination	NTRGMEEASAPGIIS CCCCCHHHCCCCHHH	9.55	27667366
745	Phosphorylation	TRGMEEASAPGIISA CCCCHHHCCCCHHHH	37.97	25850435
750	Phosphorylation	EASAPGIISALSKQD HHCCCCHHHHHHHCC	2.15	24719451
751	Phosphorylation	ASAPGIISALSKQDS HCCCCHHHHHHHCCC	22.64	29255136
754	Phosphorylation	PGIISALSKQDSDEG CCHHHHHHHCCCCCC	28.17	29255136
757	Phosphorylation	ISALSKQDSDEGSET HHHHHHCCCCCCCCC	62.89	24719451
758	Phosphorylation	SALSKQDSDEGSETM HHHHHCCCCCCCCCE	34.76	22496350
762	Phosphorylation	KQDSDEGSETMALIE HCCCCCCCCCEEEEE	28.04	22496350
764	Phosphorylation	DSDEGSETMALIEDE CCCCCCCCEEEEECH	14.94	28102081
773 (in isoform 1)	Ubiquitination	-	47.22	21906983
773 (in isoform 2)	Ubiquitination	-	47.22	21906983
778	Phosphorylation	EHNLDNTIYIPFARS HHCCCCEEEEECCCC	3.53	-
779	Phosphorylation	HNLDNTIYIPFARST HCCCCEEEEECCCCC	10.66	-
780	Ubiquitination	NLDNTIYIPFARSTP CCCCEEEEECCCCCC	1.68	22817900
780 (in isoform 3)	Ubiquitination	-	1.68	21906983
783	Ubiquitination	NTIYIPFARSTPEKK CEEEEECCCCCCCCC	10.12	22817900
784	Ubiquitination	TIYIPFARSTPEKKS EEEEECCCCCCCCCC	41.25	27667366
785	Phosphorylation	IYIPFARSTPEKKSP EEEECCCCCCCCCCC	44.90	24719451
785	Ubiquitination	IYIPFARSTPEKKSP EEEECCCCCCCCCCC	44.90	27667366
786	Phosphorylation	YIPFARSTPEKKSPL EEECCCCCCCCCCCC	29.88	30576142
791	Phosphorylation	RSTPEKKSPLSKRLS CCCCCCCCCCHHCCC	41.98	30576142
794	Phosphorylation	PEKKSPLSKRLSPQP CCCCCCCHHCCCCCH	21.08	26270265
795	Ubiquitination	EKKSPLSKRLSPQPQ CCCCCCHHCCCCCHH	66.11	21963094
796 (in isoform 1)	Ubiquitination	-	36.70	21906983
796 (in isoform 2)	Ubiquitination	-	36.70	21906983
798	Phosphorylation	SPLSKRLSPQPQIRA CCCHHCCCCCHHHHH	26.06	23401153
801	Ubiquitination	SKRLSPQPQIRAATT HHCCCCCHHHHHHHH	34.64	27667366
803	Ubiquitination	RLSPQPQIRAATTQL CCCCCHHHHHHHHHH	4.05	22817900
803 (in isoform 3)	Ubiquitination	-	4.05	21906983
804 (in isoform 1)	Ubiquitination	-	16.96	21906983
804 (in isoform 2)	Ubiquitination	-	16.96	21906983
807	Phosphorylation	QPQIRAATTQLVSNS CHHHHHHHHHHHHCC	17.68	22210691
808	Phosphorylation	PQIRAATTQLVSNSG HHHHHHHHHHHHCCC	18.38	29514088
811	Ubiquitination	RAATTQLVSNSGLAV HHHHHHHHHCCCCCC	3.51	22817900
811 (in isoform 3)	Ubiquitination	-	3.51	21906983
812	Phosphorylation	AATTQLVSNSGLAVS HHHHHHHHCCCCCCC	33.59	29514088
813	Phosphorylation	ATTQLVSNSGLAVSG HHHHHHHCCCCCCCC	32.39	24719451
814	Phosphorylation	TTQLVSNSGLAVSGK HHHHHHCCCCCCCCC	27.90	29514088
817	Ubiquitination	LVSNSGLAVSGKENK HHHCCCCCCCCCCCC	9.28	27667366
818	Ubiquitination	VSNSGLAVSGKENKL HHCCCCCCCCCCCCC	10.49	-
819	Phosphorylation	SNSGLAVSGKENKLC HCCCCCCCCCCCCCC	38.24	-
820	Ubiquitination	NSGLAVSGKENKLCT CCCCCCCCCCCCCCC	34.40	27667366
821	Ubiquitination	SGLAVSGKENKLCTP CCCCCCCCCCCCCCE	51.08	22817900
824	Ubiquitination	AVSGKENKLCTPVIC CCCCCCCCCCCEEEE	46.13	22817900
825	Ubiquitination	VSGKENKLCTPVICS CCCCCCCCCCEEEEC	6.24	27667366
831	Ubiquitination	KLCTPVICSSSTKEA CCCCEEEECCCCCCH	3.08	21963094
832	Phosphorylation	LCTPVICSSSTKEAE CCCEEEECCCCCCHH	19.05	24719451
836	Ubiquitination	VICSSSTKEAEDAPE EEECCCCCCHHHCHH	57.80	21963094
844	Ubiquitination	EAEDAPEKLSRASDM CHHHCHHHHHHHHHC	51.18	22817900
849	Phosphorylation	PEKLSRASDMKDTQL HHHHHHHHHCCHHHH	36.81	-
852	Ubiquitination	LSRASDMKDTQLLKK HHHHHHCCHHHHHHH	63.72	22817900
854	Phosphorylation	RASDMKDTQLLKKIK HHHHCCHHHHHHHHH	18.65	24719451
858	Ubiquitination	MKDTQLLKKIKEAIG CCHHHHHHHHHHHHC	62.13	27667366
859	Ubiquitination	KDTQLLKKIKEAIGK CHHHHHHHHHHHHCC	60.00	-
861	Acetylation	TQLLKKIKEAIGKIP HHHHHHHHHHHCCCC	50.39	19821557
861	Ubiquitination	TQLLKKIKEAIGKIP HHHHHHHHHHHCCCC	50.39	27667366
866	Ubiquitination	KIKEAIGKIPAATKE HHHHHHCCCCCCCCC	39.13	27667366
872	Ubiquitination	GKIPAATKEPEEQTA CCCCCCCCCHHHCCC	67.55	21963094
890	Phosphorylation	PSGCLSNSLQVKGNT CCCCCCCCEEECCCE	19.46	-
903	Ubiquitination	NTVCDGSVFTSDLMS CEEECCCCCCHHCCC	8.09	27667366
904	Phosphorylation	TVCDGSVFTSDLMSD EEECCCCCCHHCCCC	6.07	24719451
944	Ubiquitination	ANIARLQKSLRTGLL HHHHHHHHHHHHCCC	56.92	27667366
945	Phosphorylation	NIARLQKSLRTGLLE HHHHHHHHHHHCCCC	15.32	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCD14_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCD14_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCD14_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
PLAC9_HUMAN	PLAC9	physical	21988832
KDM1A_HUMAN	KDM1A	physical	23455924
STIP1_HUMAN	STIP1	physical	24613305
CEP55_HUMAN	CEP55	physical	24613305
CDK1_HUMAN	CDK1	physical	24613305
ZWINT_HUMAN	ZWINT	physical	24613305
SDCG3_HUMAN	SDCCAG3	physical	24613305
COMD8_HUMAN	COMMD8	physical	24613305
CEP85_HUMAN	CEP85	physical	24613305
SKA3_HUMAN	SKA3	physical	24613305
THOC7_HUMAN	THOC7	physical	24613305
OFD1_HUMAN	OFD1	physical	24613305
FR1OP_HUMAN	FGFR1OP	physical	24613305
HAUS2_HUMAN	HAUS2	physical	24613305
SPAG5_HUMAN	SPAG5	physical	24613305
HAUS8_HUMAN	HAUS8	physical	24613305
CEP72_HUMAN	CEP72	physical	24613305
MAGD1_HUMAN	MAGED1	physical	24613305
CNTRB_HUMAN	CNTROB	physical	24613305
CC138_HUMAN	CCDC138	physical	24613305
MPP9_HUMAN	MPHOSPH9	physical	24613305
CCNB2_HUMAN	CCNB2	physical	24613305
TRI37_HUMAN	TRIM37	physical	24613305
PIBF1_HUMAN	PIBF1	physical	24613305
CEP63_HUMAN	CEP63	physical	24613305
ATP5I_HUMAN	ATP5I	physical	26496610
KIFC3_HUMAN	KIFC3	physical	26496610
MAGA1_HUMAN	MAGEA1	physical	26496610
PCM1_HUMAN	PCM1	physical	26496610
OFD1_HUMAN	OFD1	physical	26496610
CP110_HUMAN	CCP110	physical	26496610
MOONR_HUMAN	KIAA0753	physical	26496610
KIF14_HUMAN	KIF14	physical	26496610
PIBF1_HUMAN	PIBF1	physical	26496610
FR1OP_HUMAN	FGFR1OP	physical	26496610
CP131_HUMAN	CEP131	physical	26496610
TTLL5_HUMAN	TTLL5	physical	26496610
MCM10_HUMAN	MCM10	physical	26496610
CEP72_HUMAN	CEP72	physical	26496610
MIB1_HUMAN	MIB1	physical	26496610
K1328_HUMAN	KIAA1328	physical	26496610
CSPP1_HUMAN	CSPP1	physical	26496610
CE290_HUMAN	CEP290	physical	26496610
HYI_HUMAN	HYI	physical	26496610
CCD77_HUMAN	CCDC77	physical	26496610
CE295_HUMAN	CEP295	physical	26496610
TBC31_HUMAN	TBC1D31	physical	26496610
ADIP_HUMAN	SSX2IP	physical	26496610
FOPNL_HUMAN	FOPNL	physical	26496610
SCLT1_HUMAN	SCLT1	physical	26496610
WDR90_HUMAN	WDR90	physical	26496610
CCD18_HUMAN	CCDC18	physical	26496610
CCD61_HUMAN	CCDC61	physical	26496610

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.