| UniProt ID | HYI_HUMAN | |
|---|---|---|
| UniProt AC | Q5T013 | |
| Protein Name | Putative hydroxypyruvate isomerase | |
| Gene Name | HYI | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 277 | |
| Subcellular Localization | ||
| Protein Description | Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).. | |
| Protein Sequence | MAPLRFSANLSWLFPELSGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLINTPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEDEGYKGFVGCEYQPRGDTVEGLSWLRSYWDRRGHPEAGQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 71 | Ubiquitination | TPPGDQEKGEMGLGA CCCCCHHCCCCCCCC | 55.31 | 2190698 | |
| 71 (in isoform 1) | Ubiquitination | - | 55.31 | 21906983 | |
| 71 (in isoform 3) | Ubiquitination | - | 55.31 | 21906983 | |
| 96 | Phosphorylation | GLEQAVRYAKALGCP HHHHHHHHHHHHCCC | 13.07 | 27251275 | |
| 223 | Phosphorylation | VPGRGEPSSPGELNF CCCCCCCCCCCCCCH | 44.88 | 26657352 | |
| 232 | Phosphorylation | PGELNFPYLFQLLED CCCCCHHHHHHHHHC | 18.93 | 26657352 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HYI_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HYI_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HYI_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ACY1_HUMAN | ACY1 | physical | 26344197 | |
| GRP75_HUMAN | HSPA9 | physical | 26344197 | |
| PDXK_HUMAN | PDXK | physical | 26344197 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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